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Gudrun Schiedner

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Chemicals & Drugs

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Yvonne Genzel; Stefan Kochanek; Claudia Kueppers; Erdmann Rapp; Jana Rödig; Gudrun Schiedner; Ilona Behrendt; Udo Reichl
CAP, a new human suspension cell line for influenza virus production.
Simon Fischer; Nadine Charara; Andrea Gerber; Gudrun Schiedner; Bernd Voedisch; Jens Wölfel; Sabine Geisse
Transient recombinant protein expression in a human amniocyte cell line: the CAP-T® cell system.
Nancy Larochelle; Rolf Stucka; Norman Rieger; Lothar Schermelleh; Gudrun Schiedner; Stefan Kochanek; Eckhard Wolf; Hanns Lochmüller
Genomic integration of adenoviral gene transfer vectors following transduction of fertilized mouse oocytes.

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All Publications

2013: Yvonne Genzel; Stefan Kochanek; Claudia Kueppers; Erdmann Rapp; Jana Rödig; Gudrun Schiedner; Ilona Behrendt; Udo Reichl
CAP, a new human suspension cell line for influenza virus production.
Applied microbiology and biotechnology 2013;97(1):111-22.
2012: Simon Fischer; Nadine Charara; Andrea Gerber; Gudrun Schiedner; Bernd Voedisch; Jens Wölfel; Sabine Geisse
Transient recombinant protein expression in a human amniocyte cell line: the CAP-T® cell system.
Biotechnology and bioengineering 2012;109(9):2250-61.
2011: Nancy Larochelle; Rolf Stucka; Norman Rieger; Lothar Schermelleh; Gudrun Schiedner; Stefan Kochanek; Eckhard Wolf; Hanns Lochmüller
Genomic integration of adenoviral gene transfer vectors following transduction of fertilized mouse oocytes.
Transgenic research 2011;20(1):123-35.
2008: Gudrun Schiedner; Sabine Hertel; Corinna Bialek; Helmut Kewes; Gero Waschütza; Christoph Volpers
Efficient and reproducible generation of high-expressing, stable human cell lines without need for antibiotic selection.
BMC biotechnology 2008;8():13.
2004: Zhilong Jiang; Gudrun Schiedner; Nico van Rooijen; Chau-Ching Liu; Stefan Kochanek; Paula R Clemens
Sustained muscle expression of dystrophin from a high-capacity adenoviral vector with systemic gene transfer of T cell costimulatory blockade.
Molecular therapy : the journal of the American Society of Gene Therapy 2004;10(4):688-96.
2004: Zhilong Jiang; Gudrun Schiedner; S C Gilchrist; Stefan Kochanek; Paula R Clemens
CTLA4Ig delivered by high-capacity adenoviral vector induces stable expression of dystrophin in mdx mouse muscle.
Gene therapy 2004;11(19):1453-61.
2003: Gudrun Schiedner; Wilhelm Bloch; Sabine Hertel; Marion Johnston; Andrei Molojavyi; Volker Dries; Georg Varga; Nico van Rooijen; Stefan Kochanek
A hemodynamic response to intravenous adenovirus vector particles is caused by systemic Kupffer cell-mediated activation of endothelial cells.
Human gene therapy 2003;14(17):1631-41.
2003: Marinee K L Chuah; Gudrun Schiedner; Lieven Thorrez; Brian Brown; Marion Johnston; Veerle Gillijns; Sabine Hertel; Nico van Rooijen; David Lillicrap; Désiré Collen; Thierry VandenDriessche; Stefan Kochanek
Therapeutic factor VIII levels and negligible toxicity in mouse and dog models of hemophilia A following gene therapy with high-capacity adenoviral vectors.
Blood 2003;101(5):1734-43.
2003: Gudrun Schiedner; Sabine Hertel; Marion Johnston; Volker Dries; Nico van Rooijen; Stefan Kochanek
Selective depletion or blockade of Kupffer cells leads to enhanced and prolonged hepatic transgene expression using high-capacity adenoviral vectors.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;7(1):35-43.
2002: Florian Kreppel; Volker Biermann; Stefan Kochanek; Gudrun Schiedner
A DNA-based method to assay total and infectious particle contents and helper virus contamination in high-capacity adenoviral vector preparations.
Human gene therapy 2002;13(10):1151-6.
2002: Michael Badorf; Frank Edenhofer; Volker Dries; Stefan Kochanek; Gudrun Schiedner
Efficient in vitro and in vivo excision of floxed sequences with a high-capacity adenoviral vector expressing Cre recombinase.
Genesis (New York, N.Y. : 2000) 2002;33(3):119-24.
2002: Gudrun Schiedner; Sabine Hertel; Marion Johnston; Volker Biermann; Volker Dries; Stefan Kochanek
Variables affecting in vivo performance of high-capacity adenovirus vectors.
Journal of virology 2002;76(4):1600-9.
2001: Stefan Kochanek; Gudrun Schiedner; Christoph Volpers
High-capacity 'gutless' adenoviral vectors.
Current opinion in molecular therapeutics 2001;3(5):454-63.
2001: Volker Biermann; Christoph Volpers; S Hussmann; A Stock; H Kewes; Gudrun Schiedner; A Herrmann; Stefan Kochanek
Targeting of high-capacity adenoviral vectors.
Human gene therapy 2001;12(14):1757-69.
2001: Clare E Thomas; Gudrun Schiedner; Stefan Kochanek; Maria G Castro; Pedro R Lowenstein
Preexisting antiadenoviral immunity is not a barrier to efficient and stable transduction of the brain, mediated by novel high-capacity adenovirus vectors.
Human gene therapy 2001;12(7):839-46.
2000: Gudrun Schiedner; Sabine Hertel; Stefan Kochanek
Efficient transformation of primary human amniocytes by E1 functions of Ad5: generation of new cell lines for adenoviral vector production.
Human gene therapy 2000;11(15):2105-16.
2000: Clare E Thomas; Gudrun Schiedner; Stefan Kochanek; Maria G Castro; Pedro R Löwenstein
Peripheral infection with adenovirus causes unexpected long-term brain inflammation in animals injected intracranially with first-generation, but not with high-capacity, adenovirus vectors: toward realistic long-term neurological gene therapy for chronic diseases.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(13):7482-7.
1999: Mark M Burcin; Gudrun Schiedner; Stefan Kochanek; Sophia Y Tsai; Bert W O'Malley
Adenovirus-mediated regulable target gene expression in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(2):355-60.
1998: Núria Morral; RJ Parks; Heshan Zhou; Claire Langston; Gudrun Schiedner; J Quinones; FL Graham; Stefan Kochanek; Arthur L Beaudet
High doses of a helper-dependent adenoviral vector yield supraphysiological levels of alpha1-antitrypsin with negligible toxicity.
Human gene therapy 1998;9(18):2709-16.
1998: Gudrun Schiedner; Núria Morral; RJ Parks; Ying Wu; S C Koopmans; Claire Langston; FL Graham; Arthur L Beaudet; Stefan Kochanek
Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity.
Nature genetics 1998;18(2):180-3.
1996: Gudrun Schiedner; Walter Doerfler
Insufficient levels of NFIII and its low affinity for the origin of adenovirus type 12 (Ad12) DNA replication contribute to the abortive infection of BHK21 hamster cells by Ad12.
Journal of virology 1996;70(11):8003-9.
1996: Stefan Kochanek; K Hosokawa; Gudrun Schiedner; D Renz; Walter Doerfler
DNA methylation in the promoter of ribosomal RNA genes in human cells as determined by genomic sequencing.
FEBS letters 1996;388(2-3):192-4.
1994: Gudrun Schiedner; Birgit Schmitz; Walter Doerfler
Late transcripts of adenovirus type 12 DNA are not translated in hamster cells expressing the E1 region of adenovirus type 5.
Journal of virology 1994;68(9):5476-82.