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Mario Schiffer

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Astrid Behnert; Frank Bollig; Marvin J Fritzler; Hermann Haller; Michael Mahler; Andrej Skoberne; Beina Teng; Meifeng Zhang; Mario Schiffer
An anti-phospholipase A2 receptor quantitative immunoassay and epitope analysis in membranous nephropathy reveals different antigenic domains of the receptor.
Karin Weissenborn; Hans Worthmann; Eva Bültmann; Reinhard Dengler; Xiaoqi Q Ding; Frank Donnerstag; Carsten Hafer; Hermann Haller; Hans Hartmann; Hartmut Hecker; Meike Heeren; Jan T Kielstein; Heinrich Lanfermann; Jan Menne; Thomas Pasedag; Peter Raab; Mario Schiffer; Bernhard M W Schmidt; Roland Schmitt; Ramona Schuppner; Anita B Tryc; Anja M Giesemann
Neurologic manifestations of E coli infection-induced hemolytic-uremic syndrome in adults.
Janina Mueller-Deile; Joon-Keun Park; Johannes Achenbach; Hermann Haller; Philipp Kümpers; Michael Mengel; Mario Schiffer
Podocalyxin-positive glomerular epithelial cells in urine correlate with a positive outcome in FSGS.

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All Publications

2013: Astrid Behnert; Frank Bollig; Marvin J Fritzler; Hermann Haller; Michael Mahler; Andrej Skoberne; Beina Teng; Meifeng Zhang; Mario Schiffer
An anti-phospholipase A2 receptor quantitative immunoassay and epitope analysis in membranous nephropathy reveals different antigenic domains of the receptor.
PloS one 2013;8(4):e61669.
2012: Karin Weissenborn; Hans Worthmann; Eva Bültmann; Reinhard Dengler; Xiaoqi Q Ding; Frank Donnerstag; Carsten Hafer; Hermann Haller; Hans Hartmann; Hartmut Hecker; Meike Heeren; Jan T Kielstein; Heinrich Lanfermann; Jan Menne; Thomas Pasedag; Peter Raab; Mario Schiffer; Bernhard M W Schmidt; Roland Schmitt; Ramona Schuppner; Anita B Tryc; Anja M Giesemann
Neurologic manifestations of E coli infection-induced hemolytic-uremic syndrome in adults.
Neurology 2012;79(14):1466-73.
2012: Janina Mueller-Deile; Joon-Keun Park; Johannes Achenbach; Hermann Haller; Philipp Kümpers; Michael Mengel; Mario Schiffer
Podocalyxin-positive glomerular epithelial cells in urine correlate with a positive outcome in FSGS.
Journal of nephrology 2012;25(5):802-9.
2012: Birgit Weinhold; Kirstin Worthmann; Brigitte Philippens; Wiebke Schaper; Mario Schiffer; Melanie Sellmeier; Ulrike Bernard; Linda Blume; Sebastian P Galuska; Rita Gerardy-Schahn; Hildegard Geyer; Rudolf Geyer; Stephanie Groos; Elina Kats; Anja K Münster-Kühnel
Deficits in sialylation impair podocyte maturation.
Journal of the American Society of Nephrology : JASN 2012;23(8):1319-28.
2012: Nicole Stieger; Beina Teng; Kirstin Worthmann; Anibh M Das; Stefan Engeli; Hermann Haller; Mario Schiffer
Impact of high glucose and transforming growth factor-β on bioenergetic profiles in podocytes.
Metabolism: clinical and experimental 2012;61(8):1073-86.
2012: Irini Tossidou; Mario Schiffer
TGF-β/BMP pathways and the podocyte.
Seminars in nephrology 2012;32(4):368-76.
2012: C Clajus; Jens Drube; Jens Gottlieb; Faikah Gueler; Hermann Haller; N Hanke; Jan T Kielstein; Frank Lehner; Anke Schwarz; M Stadler; Christian P Strassburg; T J Weismüller; Christoph Bara; Verena Bröcker; Mario Schiffer
Renal comorbidity after solid organ and stem cell transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2012;12(7):1691-9.
2012: L Schiffer; Mario Schiffer; C Schmitt; N Wilsdorf; Hermann Haller; Cornelia Henke-Gendo; Kais Hussein; C Klein; Hans Kreipe; Lars Pape; B Maecker-Kolhoff
CXCL13 as a novel marker for diagnosis and disease monitoring in pediatric PTLD.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2012;12(6):1610-7.
2012: Irini Tossidou; Kirstin Worthmann; Beina Teng; Hermann Haller; Benjamin L King; Malte Klaus; Rainer Niedenthal; Kevin J Peterson; Mario Schiffer
CD2AP regulates SUMOylation of CIN85 in podocytes.
Molecular and cellular biology 2012;32(6):1068-79.
2012: Jessica K Kaufeld; Irina Scheffner; Wilfried Gwinner; Hermann G Haller; Mario Schiffer
Urinary NGAL Ratio Is Not a Sensitive Biomarker for Monitoring Acute Tubular Injury in Kidney Transplant Patients: NGAL and ATI in Renal Transplant Patients.
Journal of transplantation 2012;2012():563404.
2012: Lena Schiffer; Mario Schiffer; Christoph Schroeder; Anke Schwarz; Jana Träder; Alexander A Zoerner; Jan U Becker; Frank Biertz; Verena Bröcker; Maximilian E Dämmrich; Anika Grosshennig; Hermann Haller; Christopher Jürgens; Armin Koch; Michael Mengel; Saskia Merkel; Kerstin Püllmann; Wilfried Gwinner
Rationale and design of the RIACT-study: a multi-center placebo controlled double blind study to test the efficacy of RItuximab in Acute Cellular tubulointerstitial rejection with B-cell infiltrates in renal Transplant patients: study protocol for a randomized controlled trial.
Trials 2012;13():199.
2011: Christos Chatzikyrkou; Wilfried Gwinner; Hermann Haller; Frank Lehner; Jan Menne; Bernhard M W Schmidt; Anke Schwarz; Cornelia Blume; Mario Schiffer
Pathogenesis and management of hypertension after kidney transplantation.
Journal of hypertension 2011;29(12):2283-94.
2011: Mario Schiffer; Jan T Kielstein
ABO-incompatible renal transplantation: From saline flushes to antigen-specific immunoadsorption-Tools to overcome the barrier.
The Korean journal of hematology 2011;46(3):164-8.
2011: Svjetlana Lovric; Mario Schiffer; Urte Sommerwerck; Martin Strüber; Tobias Welte; Hermann Haller; Marcus Hiss; Daniel Kayser; Jan T Kielstein; Jan U Becker; Verena Bröcker; Jens Gottlieb
Combination of everolimus with calcineurin inhibitor medication resulted in post-transplant haemolytic uraemic syndrome in lung transplant recipients--a case series.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2011;26(9):3032-8.
2011: Putri A Agustian; Clemens L Bockmeyer; Verena Bröcker; Anika Grosshennig; Wilfried Gwinner; Hans H Kreipe; Ulrich Lehmann; Friedrich Modde; Irini Schäfer; Mario Schiffer; Katharina Theophile; Jana Traeder; Jan U Becker
Diminished met signaling in podocytes contributes to the development of podocytopenia in transplant glomerulopathy.
The American journal of pathology 2011;178(5):2007-19.
2011: Nicole Stieger; Kirstin Worthmann; Mario Schiffer
The role of metabolic and haemodynamic factors in podocyte injury in diabetes.
Diabetes/metabolism research and reviews 2011;27(3):207-15.
2011: Catherine Meyer-Schwesinger; Claudia Lange; Verena Bröcker; Putri Andina Agustian; Ulrich Lehmann; Annette Raabe; Martina Brinkmeyer; Eiji Kobayashi; Mario Schiffer; Guntram Büsche; Hans H Kreipe; Friedrich Thaiss; Putri Andina Agustian; Jan U Becker
Bone marrow-derived progenitor cells do not contribute to podocyte turnover in the puromycin aminoglycoside and renal ablation models in rats.
The American journal of pathology 2011;178(2):494-9.
2011: Janina Müller-Deile; Mario Schiffer
Renal involvement in preeclampsia: similarities to VEGF ablation therapy.
Journal of pregnancy 2011;2011():176973.
2010: Anke Schwarz; Hermann Haller; R Schmitt; Mario Schiffer; Christian Koenecke; Christian P Strassburg; Frank Lehner; Jens Gottlieb; Christoph Bara; J U Becker; V Broecker
Biopsy-diagnosed renal disease in patients after transplantation of other organs and tissues.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2010;10(9):2017-25.
2010: Jan T Kielstein; Mario Schiffer; Carsten Hafer
Back to the future: extended dialysis for treatment of acute kidney injury in the intensive care unit.
Journal of nephrology 2010;23(5):494-501.
2010: Irini Tossidou; Beina Teng; Lyudmyla Drobot; Catherine Meyer-Schwesinger; Kirstin Worthmann; Hermann Haller; Mario Schiffer
CIN85/RukL is a novel binding partner of nephrin and podocin and mediates slit diaphragm turnover in podocytes.
The Journal of biological chemistry 2010;285(33):25285-95.
2010: Kirstin Worthmann; Imke Peters; Philipp Kümpers; Moin Saleem; Jan U Becker; Putri A Agustian; Johannes Achenbach; Hermann Haller; Mario Schiffer
Urinary excretion of IGFBP-1 and -3 correlates with disease activity and differentiates focal segmental glomerulosclerosis and minimal change disease.
Growth factors (Chur, Switzerland) 2010;28(2):129-38.
2010: Sharon Ashworth; Beina Teng; Jessica Kaufeld; Emily Miller; Irini Tossidou; Christoph Englert; Frank Bollig; Lynne Staggs; Ian S D Roberts; Joon-Keun Park; Hermann Haller; Mario Schiffer
Cofilin-1 inactivation leads to proteinuria--studies in zebrafish, mice and humans.
PloS one 2010;5(9):e12626.
2010: Irini Tossidou; Beina Teng; Jan Menne; Nelli Shushakova; Joon-Keun Park; Jan U Becker; Friedrich Modde; Michael Leitges; Hermann Haller; Mario Schiffer
Podocytic PKC-alpha is regulated in murine and human diabetes and mediates nephrin endocytosis.
PloS one 2010;5(4):e10185.
2009: Janina Müller-Deile; Kirstin Worthmann; Moin Saleem; Irini Tossidou; Hermann Haller; Mario Schiffer
The balance of autocrine VEGF-A and VEGF-C determines podocyte survival.
American journal of physiology. Renal physiology 2009;297(6):F1656-67.
2009: Lena Schiffer; Philipp Kümpers; Ana M Davalos-Misslitz; Marion Haubitz; Hermann Haller; Hans-Joachim Anders; Torsten Witte; Mario Schiffer
B-cell-attracting chemokine CXCL13 as a marker of disease activity and renal involvement in systemic lupus erythematosus (SLE).
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2009;24(12):3708-12.
2009: Sandhya Xavier; Thiruvur Niranjan; Stefanie Krick; Taoran Zhang; Wenjun Ju; Andrey S Shaw; Mario Schiffer; Erwin P Böttinger
TbetaRI independently activates Smad- and CD2AP-dependent pathways in podocytes.
Journal of the American Society of Nephrology : JASN 2009;20(10):2127-37.
2009: Philipp Kümpers; S David; Marion Haubitz; J Hellpap; R Horn; V Bröcker; Mario Schiffer; H Haller; T Witte
The Tie2 receptor antagonist angiopoietin 2 facilitates vascular inflammation in systemic lupus erythematosus.
Annals of the rheumatic diseases 2009;68(10):1638-43.
2009: Andrej Skoberne; Andrzej Konieczny; Mario Schiffer
Glomerular epithelial cells in the urine: what has to be done to make them worthwhile?
American journal of physiology. Renal physiology 2009;296(2):F230-41.
2009: Irini Tossidou; Gabriele Starker; Janna Kruger; Matthias Meier; Michael Leitges; Hermann Haller; Mario Schiffer
PKC-alpha modulates TGF-beta signaling and impairs podocyte survival.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2009;24(5-6):627-34.
2008: Irini Tossidou; Marc Dangers; Alexandra Koch; Dominique T Brandt; Mario Schiffer; Christian Kardinal
Tyrosine phosphatase SHP-2 is a regulator of p27(Kip1) tyrosine phosphorylation.
Cell cycle (Georgetown, Tex.) 2008;7(24):3858-68.
2008: Johannes Achenbach; Michael Mengel; Irini Tossidou; Imke Peters; Joon-Keun Park; Marion Haubitz; Jochen H H Ehrich; Hermann Haller; Mario Schiffer
Parietal epithelia cells in the urine as a marker of disease activity in glomerular diseases.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2008;23(10):3138-45.
2008: Philipp Kümpers; R Horn; G Brabant; Alexander Woywodt; Mario Schiffer; Hermann Haller; Marion Haubitz
Serum leptin and ghrelin correlate with disease activity in ANCA-associated vasculitis.
Rheumatology (Oxford, England) 2008;47(4):484-7.
2008: Lena Schiffer; Ramalingam Bethunaickan; Meera Ramanujam; Weiqing Huang; Mario Schiffer; Haiou Tao; Michael P. Madaio; Michael M Madaio; Erwin P Bottinger; Anne Davidson
Activated renal macrophages are markers of disease onset and disease remission in lupus nephritis.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(3):1938-47.
2008: Mario Schiffer; Joon-Keun Park; Irini Tossidou; Janina Bartels; Nelli Shushakova; Jan Menne; Danilo Fliser
Erythropoietin prevents diabetes-induced podocyte damage.
Kidney & blood pressure research 2008;31(6):411-5.
2008: Jochen H H Ehrich; Lars Pape; Mario Schiffer
Corticosteroid-resistant nephrotic syndrome with focal and segmental glomerulosclerosis : an update of treatment options for children.
Paediatric drugs 2008;10(1):9-22.
2007: Philipp Kümpers; Faikah Gueler; Song Rong; Michael Mengel; Irini Tossidou; Imke Peters; Hermann Haller; Mario Schiffer
Leptin is a coactivator of TGF-beta in unilateral ureteral obstructive kidney disease.
American journal of physiology. Renal physiology 2007;293(4):F1355-62.
2007: Vesna D Garovic; Steven J Wagner; Stephen T Turner; David Rosenthal; William J Watson; Brian C Brost; Carl H Rose; Larisa Gavrilova; Paula Craigo; kent bailey; Johannes Achenbach; Mario Schiffer; Joseph P Grande
Urinary podocyte excretion as a marker for preeclampsia.
American journal of obstetrics and gynecology 2007;196(4):320.e1-7.
2007: Matthias Meier; Jan Menne; Joon-Keun Park; Marcel Holtz; Faikah Gueler; Torsten Kirsch; Mario Schiffer; Michael Mengel; Carsten Lindschau; Michael Leitges; Hermann Haller
Deletion of protein kinase C-epsilon signaling pathway induces glomerulosclerosis and tubulointerstitial fibrosis in vivo.
Journal of the American Society of Nephrology : JASN 2007;18(4):1190-8.
2007: Irini Tossidou; Christian Kardinal; Imke Peters; Wilhelm Kriz; Andrey Shaw; Ivan Dikic; Sergey Tkachuk; Inna Dumler; Hermann Haller; Mario Schiffer
CD2AP/CIN85 balance determines receptor tyrosine kinase signaling response in podocytes.
The Journal of biological chemistry 2007;282(10):7457-64.
2006: Mario Schiffer; Hermann Haller
[Focal segmental glomerulosclerosis (FSGS). Molecular defects and clinical relevance].
Deutsche medizinische Wochenschrift (1946) 2006;131(27):1541-5.
2006: Imke Peters; Irini Tossidou; Johannes Achenbach; Robert P Woroniecki; Michael Mengel; Joon-Keun Park; Melanie Paschy; Kirsten De Groot; Hermann Haller; Mario Schiffer
IGF-binding protein-3 modulates TGF-beta/BMP-signaling in glomerular podocytes.
Journal of the American Society of Nephrology : JASN 2006;17(6):1644-56.
2006: Katalin Susztak; Amanda Raff; Mario Schiffer; Erwin P Böttinger
Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy.
Diabetes 2006;55(1):225-33.
2005: Mario Schiffer; Katalin Susztak; Mollie Ranalletta; Amanda Raff; Erwin P Böttinger; Maureen J Charron
Localization of the GLUT8 glucose transporter in murine kidney and regulation in vivo in nondiabetic and diabetic conditions.
American journal of physiology. Renal physiology 2005;289(1):F186-93.
2004: Mario Schiffer; Peter Mundel; Andrey S Shaw; Erwin P Böttinger
A novel role for the adaptor molecule CD2-associated protein in transforming growth factor-beta-induced apoptosis.
The Journal of biological chemistry 2004;279(35):37004-12.
2003: Katalin Susztak; Kumar Sharma; Mario Schiffer; Peter McCue; Emilio Ciccone; Erwin P Böttinger
Genomic strategies for diabetic nephropathy.
Journal of the American Society of Nephrology : JASN 2003;14(8 Suppl 3):S271-8.
2003: Lena Schiffer; Jayashree Sinha; Xiao Bo Wang; Weiqing Huang; Gero von Gersdorff; Mario Schiffer; Michael P. Madaio; Anne Davidson; Gero Von Gonsdorff
Short term administration of costimulatory blockade and cyclophosphamide induces remission of systemic lupus erythematosus nephritis in NZB/W F1 mice by a mechanism downstream of renal immune complex deposition.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(1):489-97.
2002: Mario Schiffer; Lena Schiffer; Arti Gupta; Andrey S Shaw; Ian S D Roberts; Peter Mundel; Erwin P Böttinger
Inhibitory smads and tgf-Beta signaling in glomerular cells.
Journal of the American Society of Nephrology : JASN 2002;13(11):2657-66.
2001: Mario Schiffer; Markus Bitzer; Ian S D Roberts; Jeffrey Kopp; Peter ten Dijke; Peter Mundel; Erwin P Böttinger
Apoptosis in podocytes induced by TGF-beta and Smad7.
The Journal of clinical investigation 2001;108(6):807-16.
2000: Mario Schiffer; Gero von Gersdorff; Markus Bitzer; Katalin Susztak; Erwin P Böttinger
Smad proteins and transforming growth factor-beta signaling.
Kidney international. Supplement 2000;77():S45-52.
1998: Erwin P Böttinger; J Miao; Mario Schiffer; Markus Bitzer; Ian S D Roberts
Transforming growth factor beta signal transduction in the kidney.
Kidney & blood pressure research 1998;21(2-4):259-61.