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Jürg Schifferli

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Chemicals & Drugs

Anatomy

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Physiology

Complement Activation

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Publications

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Ceylan Eken; Perrine J Martin; Salima Sadallah; Susan Treves; Jürg A Schifferli
Ectosomes of polymorphonuclear neutrophils activate multiple signaling pathways in macrophages.
C Lochmatter; K Ingram; J Keiser; C L Schneider; Jürg A Schifferli
Schistosoma mansoni tetraspanning orphan receptor (SmTOR): a new vaccine candidate against schistosomiasis.
Patricia Hirt-Minkowski; Andreas Fischer; Isabel Gröschl; Ingmar Heijnen; Marten Trendelenburg; Jürg A Schifferli
A trial of complement inhibition in a patient with cryoglobulin-induced glomerulonephritis.

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All Publications

2013: Ceylan Eken; Perrine J Martin; Salima Sadallah; Susan Treves; Jürg A Schifferli
Ectosomes of polymorphonuclear neutrophils activate multiple signaling pathways in macrophages.
Immunobiology 2013;218(3):382-92.
2012: C Lochmatter; K Ingram; J Keiser; C L Schneider; Jürg A Schifferli
Schistosoma mansoni tetraspanning orphan receptor (SmTOR): a new vaccine candidate against schistosomiasis.
Clinical and experimental immunology 2012;170(3):342-57.
2012: Patricia Hirt-Minkowski; Andreas Fischer; Isabel Gröschl; Ingmar Heijnen; Marten Trendelenburg; Jürg A Schifferli
A trial of complement inhibition in a patient with cryoglobulin-induced glomerulonephritis.
Case reports in nephrology and urology 2012;2(1):38-45.
2011: Jürg A Schifferli
Microvesicles are messengers.
Seminars in immunopathology 2011;33(5):393-4.
2011: Salima Sadallah; Ceylan Eken; Jürg A Schifferli
Ectosomes as immunomodulators.
Seminars in immunopathology 2011;33(5):487-95.
2011: Salima Sadallah; Ceylan Eken; Perrine J Martin; Jürg A Schifferli
Microparticles (ectosomes) shed by stored human platelets downregulate macrophages and modify the development of dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(11):6543-52.
2011: Salima Sadallah; C Eken; Jürg A Schifferli
Ectosomes as modulators of inflammation and immunity.
Clinical and experimental immunology 2011;163(1):26-32.
2010: Ceylan Eken; Perrine J Martin; Salima Sadallah; Susan Treves; Monica Schaller; Jürg A Schifferli
Ectosomes released by polymorphonuclear neutrophils induce a MerTK-dependent anti-inflammatory pathway in macrophages.
The Journal of biological chemistry 2010;285(51):39914-21.
2010: Nina Kononowa; Jürg A Schifferli
[Fever of unknown origin (FUO)].
Therapeutische Umschau. Revue thérapeutique 2010;67(12):645-7.
2010: Salima Sadallah; Shlemen Hanno; Jürg A Schifferli
Reticulocytes have a higher resistance to complement lysis than erythrocytes.
Acta haematologica 2010;123(3):153-7.
2010: Patricia Hirt-Minkowski; Michael Dickenmann; Jürg A Schifferli
Atypical hemolytic uremic syndrome: update on the complement system and what is new.
Nephron. Clinical practice 2010;114(4):c219-35.
2009: Patricia Hirt-Minkowski; Stefan Schaub; Michael Mayr; Jürg A Schifferli; Michael Dickenmann; Véronique Frémeaux-Bacchi; Jürg Steiger
Haemolytic uraemic syndrome caused by factor H mutation: is single kidney transplantation under intensive plasmatherapy an option?
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2009;24(11):3548-51.
2009: C Lochmatter; Jürg A Schifferli; P J Martin
Schistosoma mansoni TOR is a tetraspanning orphan receptor on the parasite surface.
Parasitology 2009;136(5):487-98.
2008: Salima Sadallah; Ceylan Eken; Jürg A Schifferli
Erythrocyte-derived ectosomes have immunosuppressive properties.
Journal of leukocyte biology 2008;84(5):1316-25.
2008: Pierre Lescuyer; Agnès Pernin; Alexandre Hainard; Caty Bigeire; Jennifer A Burgess; Catherine Zimmermann-Ivol; Jean-Charles Sanchez; Jürg A Schifferli; Denis F Hochstrasser; Solange Moll
Proteomic analysis of a podocyte vesicle-enriched fraction from human normal and pathological urine samples.
Proteomics. Clinical applications 2008;2(7-8):1008-18.
2008: Tilman Drescher; Theresia Klima; Jürg A Schifferli
Seizures, hyponatraemia, and "poison".
Lancet 2008;371(9630):2144.
2008: Ceylan Eken; Olivier Gasser; Gabriela Zenhaeusern; Ineke Oehri; Christoph Hess; Jürg A Schifferli
Polymorphonuclear neutrophil-derived ectosomes interfere with the maturation of monocyte-derived dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(2):817-24.
2007: Marten Trendelenburg; Jürg A Schifferli
Rituximab in a patient with Hyper-IgE syndrome.
Archives of dermatology 2007;143(6):807-8.
2007: Jürg A Schifferli
Case 40-2006: anemia and low HDL cholesterol.
The New England journal of medicine 2007;356(18):1893-5; author reply 1893-5.
2007: Marie-Anne Rameix-Welti; Catherine H Régnier; Frank Bienaimé; Jacques Blouin; Jürg A Schifferli; Wolf H Fridman; Catherine Sautès-Fridman; Véronique Frémeaux-Bacchi
Hereditary complement C7 deficiency in nine families: subtotal C7 deficiency revisited.
European journal of immunology 2007;37(5):1377-85.
2006: Marten Trendelenburg; Margarita Lopez-Trascasa; Eliska Potlukova; Solange Moll; Stephan Regenass; Véronique Frémeaux-Bacchi; Jorge Martinez-Ara; Eva Jancova; Mari Luz Picazo; Eva Honsova; Vladimír Tesar; Salima Sadallah; Jürg A Schifferli
High prevalence of anti-C1q antibodies in biopsy-proven active lupus nephritis.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2006;21(11):3115-21.
2006: Rebecca Schirinzi; Jean Pierre Lantin; Véronique Frémeaux-Bacchi; Jürg A Schifferli; Marten Trendelenburg
[Combined-heterozygous deficiency of complement C7 in a patient with recurrent meningitis].
Medizinische Klinik (Munich, Germany : 1983) 2006;101(8):655-8.
2006: David Saadoun; Salima Sadallah; Marten Trendelenburg; Nicolas Limal; Damien Sene; Jean-Charles Piette; Jürg A Schifferli; Patrice Cacoub
Anti-C1q antibodies in hepatitis C virus infection.
Clinical and experimental immunology 2006;145(2):308-12.
2006: Daniel Robert; Stefano Barelli; David Crettaz; Pierre-Alexandre Bart; Jürg A Schifferli; Daniel C Betticher; Jean-Daniel Tissot
Clinical proteomics: study of a cryogel.
Proteomics 2006;6(13):3958-60.
2006: S Moll; S Lange; M J Mihatsch; Z Dragic; Jürg A Schifferli; Jameel M Inal
CRIT is expressed on podocytes in normal human kidney and upregulated in membranous nephropathy.
Kidney international 2006;69(11):1961-8.
2006: Kwok-Min Hui; Bergljot Magnadottir; Jürg A Schifferli; Jameel M Inal
CRIT peptide interacts with factor B and interferes with alternative pathway activation.
Biochemical and biophysical research communications 2006;344(1):308-14.
2006: Ina Kozyro; Iryna Perahud; Salima Sadallah; Alexander Sukalo; Leonid Titov; Jürg A Schifferli; Marten Trendelenburg
Clinical value of autoantibodies against C1q in children with glomerulonephritis.
Pediatrics 2006;117(5):1663-8.
2005: Jürg A Schifferli
Complement: a member of the innate immune system.
Springer seminars in immunopathology 2005;27(3):273-5.
2005: David Pilzer; Olivier Gasser; Oren Moskovich; Jürg A Schifferli; Zvi Fishelson
Emission of membrane vesicles: roles in complement resistance, immunity and cancer.
Springer seminars in immunopathology 2005;27(3):375-87.
2005: Jameel M Inal; Sylvie Miot; Jürg A Schifferli
The complement inhibitor, CRIT, undergoes clathrin-dependent endocytosis.
Experimental cell research 2005;310(1):54-65.
2005: Jürg A Schifferli
[Shared decision making: a new challenge for the physicians?].
Praxis 2005;94(39):1505-7.
2005: Kwok-Min Hui; George L Orriss; Tilman Schirmer; Bergljot Magnadottir; Jürg A Schifferli; Jameel M Inal
Expression of functional recombinant von Willebrand factor-A domain from human complement C2: a potential binding site for C4 and CRIT.
The Biochemical journal 2005;389(Pt 3):863-8.
2005: Olivier Gasser; Jürg A Schifferli
Microparticles released by human neutrophils adhere to erythrocytes in the presence of complement.
Experimental cell research 2005;307(2):381-7.
2005: Marten Trendelenburg; Jürg A Schifferli
[Rheumatoid arthritis (RA) and systemic lupus erythematosus(SLE)].
Therapeutische Umschau. Revue thérapeutique 2005;62(5):263.
2005: Salima Sadallah; Markus Heim; Christoph Hess; Thomas Klimkait; Manuel Battegay; Jürg A Schifferli
Contrary to HIV, hepatitis C virus is not associated with erythrocytes in vivo.
Journal of hepatology 2005;42(1):150-2.
2005: Jameel M Inal; Kwok-Min Hui; Sylvie Miot; Sigrun Lange; Marcel Ivan Ramirez; Brigitte Schneider; Gerhard Krueger; Jürg A Schifferli
Complement C2 receptor inhibitor trispanning: a novel human complement inhibitory receptor.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(1):356-66.
2004: M A E Buylaert; Jürg A Schifferli
[Acute renal failure--"a well meant present from a friend"].
Therapeutische Umschau. Revue thérapeutique 2004;61(12):725-7.
2004: Olivier Gasser; Jürg A Schifferli
Activated polymorphonuclear neutrophils disseminate anti-inflammatory microparticles by ectocytosis.
Blood 2004;104(8):2543-8.
2004: Eliska Horakova; Olivier Gasser; Salima Sadallah; Jameel M Inal; Guillaume Bourgeois; Ingrid Ziekau; Thomas Klimkait; Jürg A Schifferli
Complement mediates the binding of HIV to erythrocytes.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(6):4236-41.
2003: Marten Trendelenburg; Jürg A Schifferli
Cryoglobulins in chronic hepatitis C virus infection.
Clinical and experimental immunology 2003;133(2):153-5.
2003: Christoph Hess; Jürg A Schifferli
Immune adherence revisited: novel players in an old game.
News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society 2003;18():104-8.
2003: Olivier Gasser; Christoph Hess; Sylvie Miot; Catherine Deon; jean-charles sanchez; Jürg A Schifferli
Characterisation and properties of ectosomes released by human polymorphonuclear neutrophils.
Experimental cell research 2003;285(2):243-57.
2003: Jameel M Inal; Brigitte Schneider; Marta Armanini; Jürg A Schifferli
A peptide derived from the parasite receptor, complement C2 receptor inhibitor trispanning, suppresses immune complex-mediated inflammation in mice.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(8):4310-7.
2003: Stefan Franz; Mirabel A Buylaert; Solange Moll; Jürg A Schifferli
A well-meant present from a friend.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2003;18(3):613-4.
2003: Jameel M Inal; Manuel Pascual; Philippe Lesavre; Jürg A Schifferli
Complement inhibition in renal diseases.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2003;18(2):237-40.
2003: Marten Trendelenburg; H U Lutz; Jean-Daniel Tissot; Solange Moll; T Hoffmann; Jürg A Schifferli
Cryoglobulin/albumin complexes in a patient with severe autoimmune syndrome.
Scandinavian journal of rheumatology 2003;32(6):367-73.
2003: Salima Sadallah; Christoph Hess; Marten Trendelenburg; Christian A Vedeler; Margarita Lopez-Trascasa; Jürg A Schifferli
Autoantibodies against complement receptor 1 (CD35) in SLE, liver cirrhosis and HIV-infected patients.
Clinical and experimental immunology 2003;131(1):174-81.
2002: Véronique Frémeaux-Bacchi; Laure-Hélène Noël; Jürg A Schifferli
No lupus nephritis in the absence of antiC1q autoantibodies?
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2002;17(12):2041-3.
2002: Sylvie Miot; Jutta Marfurt; Estelle Lach-Trifilieff; Carolina González-Rubio; Margarita López-Trascasa; Salima Sadallah; Jürg A Schifferli
The mechanism of loss of CR1 during maturation of erythrocytes is different between factor I deficient patients and healthy donors.
Blood cells, molecules & diseases 2002;29(2):200-12.
2002: Christoph Hess; Thomas Klimkait; Luregn Schlapbach; Veronika Del Zenero; Salima Sadallah; Eliska Horakova; Gianmarco Balestra; Verena Werder; Christoph Schaefer; Manuel Battegay; Jürg A Schifferli
Association of a pool of HIV-1 with erythrocytes in vivo: a cohort study.
Lancet 2002;359(9325):2230-4.
2002: Jameel M Inal; Jürg A Schifferli
Complement C2 receptor inhibitor trispanning and the beta-chain of C4 share a binding site for complement C2.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(10):5213-21.
2002: Jean-Daniel Tissot; jean-charles sanchez; Françoise Vuadens; Alexander Scherl; Jürg A Schifferli; Denis F Hochstrasser; Philippe Schneider; Michel A Duchosal
IgM are associated to Sp alpha (CD5 antigen-like).
Electrophoresis 2002;23(7-8):1203-6.
2002: Sylvie Miot; Sophie Crespo; Jürg A Schifferli
Distinct forms of DAF in urine and blood.
Journal of immunological methods 2002;260(1-2):43-53.
2001: Emiliana Jelezarova; M Schlumberger; Salima Sadallah; Peter J Späth; Jürg A Schifferli; Hans U Lutz
A C3 convertase assay for nephritic factor functional activity.
Journal of immunological methods 2001;251(1-2):45-52.
2001: Gabriella Moroni; Marten Trendelenburg; Nicoletta Del Papa; Silvana Quaglini; Elena Raschi; Paola Panzeri; Cinzia Testoni; Angela Tincani; Giovanni Banfi; Genesio Balestrieri; Jürg A Schifferli; Pier Luigi Meroni; Claudio Ponticelli
Anti-C1q antibodies may help in diagnosing a renal flare in lupus nephritis.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2001;37(3):490-8.
2001: Solange Moll; Sylvie Miot; Salima Sadallah; Fred Gudat; M J Mihatsch; Jürg A Schifferli
No complement receptor 1 stumps on podocytes in human glomerulopathies.
Kidney international 2001;59(1):160-8.
2000: Marten Trendelenburg; Jürg A Schifferli
[New physiopathological findings in paraproteinemias].
Schweizerische medizinische Wochenschrift 2000;130(44):1639-42.
2000: Christoph Hess; Salima Sadallah; Jürg A Schifferli
Induction of neutrophil responsiveness to myeloperoxidase antibodies by their exposure to supernatant of degranulated autologous neutrophils.
Blood 2000;96(8):2822-7.
2000: Marten Trendelenburg; Jürg A Schifferli
[Apoptosis and C1q: possible explanations for the pathogenesis of systemic lupus erythematosus].
Zeitschrift für Rheumatologie 2000;59(3):172-5.
2000: M Kondo-Oestreicher; C Chizzolini; Jean-Daniel Tissot; C Girardet; E Schiffer; J M Reymond; Jürg A Schifferli
Hypocomplementemic panniculitis with paraprotein.
The Journal of rheumatology 2000;27(4):1091-5.
2000: Kjell-Morten Myhr; Salima Sadallah; T E Mollnes; Seppo Meri; Harald Nyland; Jürg A Schifferli; Christian A Vedeler
Interferon-alpha2a effects on complement activation and regulation in MS patients.
Acta neurologica Scandinavica 2000;101(1):30-5.
1999: Marten Trendelenburg; Christoph Hess; M Kondo-Oestreicher; Jean-Daniel Tissot; Peter J Späth; Jürg A Schifferli
Monomeric complement-activating IgG paraproteins.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(12):6924-32.
1999: Salima Sadallah; Christoph Hess; Sylvie Miot; Olivier Spertini; Hans U Lutz; Jürg A Schifferli
Elastase and metalloproteinase activities regulate soluble complement receptor 1 release.
European journal of immunology 1999;29(11):3754-61.
1999: Christoph Hess; Salima Sadallah; A Hefti; R Landmann; Jürg A Schifferli
Ectosomes released by human neutrophils are specialized functional units.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(8):4564-73.
1999: Marten Trendelenburg; S Courvoisier; Peter J Späth; Solange Moll; M Mihatsch; P Itin; Jürg A Schifferli
Hypocomplementemic urticarial vasculitis or systemic lupus erythematosus?
American journal of kidney diseases : the official journal of the National Kidney Foundation 1999;34(4):745-51.
1999: E Lach-Trifilieff; Jutta Marfurt; S Schwarz; Salima Sadallah; Jürg A Schifferli
Complement receptor 1 (CD35) on human reticulocytes: normal expression in systemic lupus erythematosus and HIV-infected patients.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(12):7549-54.
1999: Salima Sadallah; Fred Gudat; Jean Laissue; P J Spath; Jürg A Schifferli
Glomerulonephritis in a patient with complement factor I deficiency.
American journal of kidney diseases : the official journal of the National Kidney Foundation 1999;33(6):1153-7.
1999: Marten Trendelenburg; Jutta Marfurt; I Gerber; Alan Tyndall; Jürg A Schifferli
Lack of occurrence of severe lupus nephritis among anti-C1q autoantibody-negative patients.
Arthritis and rheumatism 1999;42(1):187-8.
1999: Salima Sadallah; E Lach; S Schwarz; A Gratwohl; Olivier Spertini; Jürg A Schifferli
Soluble complement receptor 1 is increased in patients with leukemia and after administration of granulocyte colony-stimulating factor.
Journal of leukocyte biology 1999;65(1):94-101.
1998: Marten Trendelenburg; Jürg A Schifferli
[Is autoantibody determination in patients with systemic lupus erythematosus useful? Anti-C1q-autoantibody as an example].
Praxis 1998;87(51-52):1811-3.
1998: Joann M Moulds; M Brai; J Cohen; AG Cortelazzo; Mariaclara Cuccia; M Lin; Salima Sadallah; Jürg A Schifferli; V Bala Subramanian; L Truedsson; G W Wu; F Zhang; John P Atkinson
Reference typing report for complement receptor 1 (CR1).
Experimental and clinical immunogenetics 1998;15(4):291-4.
1998: Jürg Hamacher; Salima Sadallah; Jürg A Schifferli; J Villard; Laurent Nicod
Soluble complement receptor type 1 (CD35) in bronchoalveolar lavage of inflammatory lung diseases.
The European respiratory journal 1998;11(1):112-9.
1998: Marten Trendelenburg; Jürg A Schifferli
Cryoglobulins are not essential.
Annals of the rheumatic diseases 1998;57(1):3-5.
1997: Salima Sadallah; E Lach; Hans U Lutz; S Schwarz; P A Guerne; Jürg A Schifferli
CR1, CD35 in synovial fluid from patients with inflammatory joint diseases.
Arthritis and rheumatism 1997;40(3):520-6.