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Michael Schindler

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Publications

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Sebastian Bolduan; Oliver T Fackler; Joëlle V Fritz; Kristin Höhne; Philipp Hubel; Frank Kirchhoff; Veronika Lodermeyer; Tatjana Reif; Daniel Sauter; Michael Schindler; Ulrich Schubert
HIV-1 Vpu affects the anterograde transport and the glycosylation pattern of NTB-A.
Raphaël Gaudin; François-Xavier Gobert; Mabel Jouve; Emmanuel Le Bouder; Michael Schindler; Aditi Varthaman; Bruna Cunha de Alencar; Stefano Bèrre; Philippe Benaroch
Critical role for the kinesin KIF3A in the HIV life cycle in primary human macrophages.
Sebastian Bolduan; Timo Greiner; Herwig Koppensteiner; Veronika Lodermeyer; Michael Schindler; Gerhard Thiel; Jörg Votteler; Ulrich Schubert
Ion channel activity of HIV-1 Vpu is dispensable for counteraction of CD317.

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All Publications

2013: Sebastian Bolduan; Oliver T Fackler; Joëlle V Fritz; Kristin Höhne; Philipp Hubel; Frank Kirchhoff; Veronika Lodermeyer; Tatjana Reif; Daniel Sauter; Michael Schindler; Ulrich Schubert
HIV-1 Vpu affects the anterograde transport and the glycosylation pattern of NTB-A.
Virology 2013;440(2):190-203.
2012: Raphaël Gaudin; François-Xavier Gobert; Mabel Jouve; Emmanuel Le Bouder; Michael Schindler; Aditi Varthaman; Bruna Cunha de Alencar; Stefano Bèrre; Philippe Benaroch
Critical role for the kinesin KIF3A in the HIV life cycle in primary human macrophages.
The Journal of cell biology 2012;199(3):467-79.
2011: Sebastian Bolduan; Timo Greiner; Herwig Koppensteiner; Veronika Lodermeyer; Michael Schindler; Gerhard Thiel; Jörg Votteler; Ulrich Schubert
Ion channel activity of HIV-1 Vpu is dispensable for counteraction of CD317.
Virology 2011;416(1-2):75-85.
2010: Philippe Benaroch; Elisabeth Billard; Raphaël Gaudin; Michael Schindler; Mabel Jouve
HIV-1 assembly in macrophages.
Retrovirology 2010;7():29.
2009: Gabriela Turk; Swantje Gundlach; Mauricio Carobene; Michael Schindler; Horacio Salomon; Philippe Benaroch
Single Nef proteins from HIV type 1 subtypes C and F fail to upregulate invariant chain cell surface expression but are active for other functions.
AIDS research and human retroviruses 2009;25(3):285-96.
2009: Jan Schmökel; Hui Li; Elizabeth Bailes; Michael Schindler; Guido Silvestri; Beatrice H Hahn; Cristian Apetrei; Frank Kirchhoff
Conservation of Nef function across highly diverse lineages of SIVsmm.
Retrovirology 2009;6():36.
2008: Hélène Toussaint; François-Xavier Gobert; Michael Schindler; Carina Banning; Patrycja Kozik; Mabel Jouve; Frank Kirchhoff; Philippe Benaroch
Human immunodeficiency virus type 1 nef expression prevents AP-2-mediated internalization of the major histocompatibility complex class II-associated invariant chain.
Journal of virology 2008;82(17):8373-82.
2008: Frank Kirchhoff; Michael Schindler; Anke Specht; N Arhel; Jan Münch
Role of Nef in primate lentiviral immunopathogenesis.
Cellular and molecular life sciences : CMLS 2008;65(17):2621-36.
2008: Michael Schindler; Jan Schmökel; Anke Specht; Hui Li; Jan Münch; Mohammad Khalid; Donald L Sodora; Beatrice H Hahn; Guido Silvestri; Frank Kirchhoff
Inefficient Nef-mediated downmodulation of CD3 and MHC-I correlates with loss of CD4+T cells in natural SIV infection.
PLoS pathogens 2008;4(7):e1000107.
2008: Anke Specht; M Quinn DeGottardi; Michael Schindler; Beatrice Hahn; David T Evans; Frank Kirchhoff
Selective downmodulation of HLA-A and -B by Nef alleles from different groups of primate lentiviruses.
Virology 2008;373(1):229-37.
2007: Jan Münch; Elke Rücker; Ludger Ständker; Knut Adermann; Christine Goffinet; Michael Schindler; Steffen Wildum; Raghavan Chinnadurai; Devi Rajan; Anke Specht; Guillermo Giménez-Gallego; Pedro Cuevas Sánchez; Fowler Douglas; Atanas Koulov; Jeffery W Kelly; Walther Mothes; Jean-Charles Grivel; Leonid Margolis; Oliver T Keppler; Wolf-Georg Forssmann; Frank Kirchhoff
Semen-derived amyloid fibrils drastically enhance HIV infection.
Cell 2007;131(6):1059-71.
2007: Jan Münch; Devi Rajan; Michael Schindler; Anke Specht; Elke Rücker; Francis J Novembre; Eric Nerrienet; Michaela C Müller-Trutwin; Martine Peeters; Beatrice H Hahn; Frank Kirchhoff
Nef-mediated enhancement of virion infectivity and stimulation of viral replication are fundamental properties of primate lentiviruses.
Journal of virology 2007;81(24):13852-64.
2007: Michael Schindler; Devi Rajan; Anke Specht; Carolin Ritter; Kati Pulkkinen; Kalle Saksela; Frank Kirchhoff
Association of Nef with p21-activated kinase 2 is dispensable for efficient human immunodeficiency virus type 1 replication and cytopathicity in ex vivo-infected human lymphoid tissue.
Journal of virology 2007;81(23):13005-14.
2007: Michael Schindler; Steffen Wildum; Nicoletta Casartelli; Margherita Doria; Frank Kirchhoff
Nef alleles from children with non-progressive HIV-1 infection modulate MHC-II expression more efficiently than those from rapid progressors.
AIDS (London, England) 2007;21(9):1103-7.
2007: Elena Priceputu; Zaher Hanna; Chunyan Hu; Marie-Chantal Simard; Patrick Vincent; Steffen Wildum; Michael Schindler; Frank Kirchhoff; Paul Jolicoeur
Primary human immunodeficiency virus type 1 nef alleles show major differences in pathogenicity in transgenic mice.
Journal of virology 2007;81(9):4677-93.
2007: Jan Münch; Ludger Ständker; Knut Adermann; Axel Schulz; Michael Schindler; Raghavan Chinnadurai; Stefan Pöhlmann; Chawaree Chaipan; Thorsten Biet; Thomas Peters; Bernd Meyer; Dennis Wilhelm; Hong Lu; Weiguo Jing; Shibo Jiang; Wolf-Georg Forssmann; Frank Kirchhoff
Discovery and optimization of a natural HIV-1 entry inhibitor targeting the gp41 fusion peptide.
Cell 2007;129(2):263-75.
2006: Steffen Wildum; Michael Schindler; Jan Münch; Frank Kirchhoff
Contribution of Vpu, Env, and Nef to CD4 down-modulation and resistance of human immunodeficiency virus type 1-infected T cells to superinfection.
Journal of virology 2006;80(16):8047-59.
2006: Michael Schindler; Jan Münch; Olaf Kutsch; Hui Li; Mario L Santiago; Frederic Bibollet-Ruche; Michaela C Müller-Trutwin; Francis J Novembre; Martine Peeters; Valerie Courgnaud; Elizabeth Bailes; Pierre Roques; Donald L Sodora; Guido Silvestri; Paul M Sharp; Beatrice H Hahn; Frank Kirchhoff
Nef-mediated suppression of T cell activation was lost in a lentiviral lineage that gave rise to HIV-1.
Cell 2006;125(6):1055-67.
2006: Matthias Brenner; Jan Münch; Michael Schindler; Steffen Wildum; Nicole Stolte; Christiane Stahl-Hennig; Dietmar Fuchs; Kerstin Mätz-Rensing; Monika Franz; Jonathan Luke Heeney; Peter Ten Haaft; Tomek Swigut; Kasia Hrecka; Jacek Skowronski; Frank Kirchhoff
Importance of the N-distal AP-2 binding element in Nef for simian immunodeficiency virus replication and pathogenicity in rhesus macaques.
Journal of virology 2006;80(9):4469-81.
2006: Devi Rajan; Steffen Wildum; Elke Rücker; Michael Schindler; Frank Kirchhoff
Effect of R77Q, R77A and R80A changes in Vpr on HIV-1 replication and CD4 T cell depletion in human lymphoid tissue ex vivo.
AIDS (London, England) 2006;20(6):831-6.
2005: Kasia Hrecka; Tomek Swigut; Michael Schindler; Frank Kirchhoff; Jacek Skowronski
Nef proteins from diverse groups of primate lentiviruses downmodulate CXCR4 to inhibit migration to the chemokine stromal derived factor 1.
Journal of virology 2005;79(16):10650-9.
2005: Jan Münch; Michael Schindler; Steffen Wildum; Elke Rücker; Nicola Bailer; Volker Knoop; Francis J Novembre; Frank Kirchhoff
Primary sooty mangabey simian immunodeficiency virus and human immunodeficiency virus type 2 nef alleles modulate cell surface expression of various human receptors and enhance viral infectivity and replication.
Journal of virology 2005;79(16):10547-60.
2005: Michael Schindler; Jan Münch; Frank Kirchhoff
Human immunodeficiency virus type 1 inhibits DNA damage-triggered apoptosis by a Nef-independent mechanism.
Journal of virology 2005;79(9):5489-98.
2004: Michael Schindler; Jan Münch; Matthias Brenner; Christiane Stahl-Hennig; Jacek Skowronski; Frank Kirchhoff
Comprehensive analysis of nef functions selected in simian immunodeficiency virus-infected macaques.
Journal of virology 2004;78(19):10588-97.
2004: Frank Kirchhoff; Michael Schindler; Nicola Bailer; G Herma Renkema; Kalle Saksela; Volker Knoop; Michaela C Müller-Trutwin; Mario L Santiago; Frederic Bibollet-Ruche; Matthias T Dittmar; Jonathan Luke Heeney; Beatrice H Hahn; Jan Münch
Nef proteins from simian immunodeficiency virus-infected chimpanzees interact with p21-activated kinase 2 and modulate cell surface expression of various human receptors.
Journal of virology 2004;78(13):6864-74.
2003: Kirsten Hiebenthal-Millow; Thomas C Greenough; Doreen B Bretttler; Michael Schindler; Steffen Wildum; John L Sullivan; Frank Kirchhoff
Alterations in HIV-1 LTR promoter activity during AIDS progression.
Virology 2003;317(1):109-18.
2003: Michael Schindler; Stephanie Würfl; Philippe Benaroch; Thomas C Greenough; Rod Daniels; Philippa Easterbrook; Matthias Brenner; Jan Münch; Frank Kirchhoff
Down-modulation of mature major histocompatibility complex class II and up-regulation of invariant chain cell surface expression are well-conserved functions of human and simian immunodeficiency virus nef alleles.
Journal of virology 2003;77(19):10548-56.