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Achim Schlapbach

Research Profile

Chemicals & Drugs

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Mouse

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Drug Design

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Cell Line

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Publications

TOP 3
Laszlo Revesz; Achim Schlapbach; Reiner Aichholz; Roland Feifel; Stuart Hawtin; Richard Heng; Peter Hiestand; Wolfgang Jahnke; Guido Koch; Markus Kroemer; Henrik Möbitz; Clemens Scheufler; Juraj Velcicky; Christine Huppertz
In vivo and in vitro SAR of tetracyclic MAPKAP-K2 (MK2) inhibitors. Part I.
Laszlo Revesz; Achim Schlapbach; Reiner Aichholz; Janet Dawson; Roland Feifel; Stuart Hawtin; Amanda Littlewood-Evans; Guido Koch; Markus Kroemer; Henrik Möbitz; Clemens Scheufler; Juraj Velcicky; Christine Huppertz
In vivo and in vitro SAR of tetracyclic MAPKAP-K2 (MK2) inhibitors. Part II.
Juraj Velcicky; Roland Feifel; Stuart Hawtin; Richard Heng; Christine Huppertz; Guido Koch; Markus Kroemer; Henrik Moebitz; Laszlo Revesz; Clemens Scheufler; Achim Schlapbach
Novel 3-aminopyrazole inhibitors of MK-2 discovered by scaffold hopping strategy.

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All Publications

2010: Laszlo Revesz; Achim Schlapbach; Reiner Aichholz; Roland Feifel; Stuart Hawtin; Richard Heng; Peter Hiestand; Wolfgang Jahnke; Guido Koch; Markus Kroemer; Henrik Möbitz; Clemens Scheufler; Juraj Velcicky; Christine Huppertz
In vivo and in vitro SAR of tetracyclic MAPKAP-K2 (MK2) inhibitors. Part I.
Bioorganic & medicinal chemistry letters 2010;20(15):4715-8.
2010: Laszlo Revesz; Achim Schlapbach; Reiner Aichholz; Janet Dawson; Roland Feifel; Stuart Hawtin; Amanda Littlewood-Evans; Guido Koch; Markus Kroemer; Henrik Möbitz; Clemens Scheufler; Juraj Velcicky; Christine Huppertz
In vivo and in vitro SAR of tetracyclic MAPKAP-K2 (MK2) inhibitors. Part II.
Bioorganic & medicinal chemistry letters 2010;20(15):4719-23.
2010: Juraj Velcicky; Roland Feifel; Stuart Hawtin; Richard Heng; Christine Huppertz; Guido Koch; Markus Kroemer; Henrik Moebitz; Laszlo Revesz; Clemens Scheufler; Achim Schlapbach
Novel 3-aminopyrazole inhibitors of MK-2 discovered by scaffold hopping strategy.
Bioorganic & medicinal chemistry letters 2010;20(3):1293-7.
2009: Achim Schlapbach; Christine Huppertz
Low-molecular-weight MK2 inhibitors: a tough nut to crack!
Future medicinal chemistry 2009;1(7):1243-57.
2008: Achim Schlapbach; Roland Feifel; Stuart Hawtin; Richard Heng; Guido Koch; Henrik Moebitz; Laszlo Revesz; Clemens Scheufler; Juraj Velcicky; Rudolf Waelchli; Christine Huppertz
Pyrrolo-pyrimidones: a novel class of MK2 inhibitors with potent cellular activity.
Bioorganic & medicinal chemistry letters 2008;18(23):6142-6.
2007: Volha Ninichuk; Andrej Khandoga; Stephan Segerer; Pius Loetscher; Achim Schlapbach; Laszlo Revesz; Roland Feifel; Andrej Khandoga; Fritz Krombach; Peter J Nelson; Detlef Schlöndorff; Hans-Joachim Anders
The role of interstitial macrophages in nephropathy of type 2 diabetic db/db mice.
The American journal of pathology 2007;170(4):1267-76.
2006: Rudolf Waelchli; Birgit Bollbuck; Christian Bruns; Thomas Buhl; Jörg Eder; Roland Feifel; Rene Hersperger; Philipp Janser; Laszlo Revesz; Hans-Günter Zerwes; Achim Schlapbach
Design and preparation of 2-benzamido-pyrimidines as inhibitors of IKK.
Bioorganic & medicinal chemistry letters 2006;16(1):108-12.
2005: Laszlo Revesz; Birgit Bollbuck; Thomas Buhl; Jörg Eder; Ronald Esser; Roland Feifel; Richard Heng; Peter Hiestand; Benedicte Jachez-Demange; Pius Loetscher; Helmut Sparrer; Achim Schlapbach; Rudolf Waelchli
Novel CCR1 antagonists with oral activity in the mouse collagen induced arthritis.
Bioorganic & medicinal chemistry letters 2005;15(23):5160-4.
2004: Achim Schlapbach; Richard Heng; Franco E Di Padova
A novel Pd-catalyzed cyclization reaction of ureas for the synthesis of dihydroquinazolinone p38 kinase inhibitors.
Bioorganic & medicinal chemistry letters 2004;14(2):357-60.