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Michael Schleicher

Research Profile

Chemicals & Drugs

Genes & Molecular Sequences

Amino Acid Sequences

Concepts & Ideas

Anatomy

Cytoskeleton

Physiology

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Cloning, Molecular

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Protein Binding

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TOP 3
Vivek S Peche; Gabriele Pfitzer; Michael Schleicher; Jan Schrickel; Robert Stehle; Florian Stöckigt; F Thomas Wunderlich; Klaus Nohroudi; Klaus Addicks; Bhagyashri D Burgute; Fatiha Elhamine; Julia Gallinger; Tad A Holak; Sushant P Kale; Kosmas Kosmas; Angelika A Noegel
Ablation of cyclase-associated protein 2 (CAP2) leads to cardiomyopathy.
Yulia Artemenko; Petros Batsios; Jane Borleis; Zachary Gagnon; Josephine Lee; Meino Rohlfs; Doriane Sanséau; Michael Schleicher; Stacey S Willard; Peter N Devreotes
Tumor suppressor Hippo/MST1 kinase mediates chemotaxis by regulating spreading and adhesion.
Hameeda Sultana; Rosemarie Blau-Wasser; G Neelakanta; Francisco Rivero; Michael Schleicher; Angelika A Noegel
Ectopic expression of cyclase associated protein CAP restores the streaming and aggregation defects of adenylyl cyclase a deficient Dictyostelium discoideum cells.

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All Publications

2013: Vivek S Peche; Gabriele Pfitzer; Michael Schleicher; Jan Schrickel; Robert Stehle; Florian Stöckigt; F Thomas Wunderlich; Klaus Nohroudi; Klaus Addicks; Bhagyashri D Burgute; Fatiha Elhamine; Julia Gallinger; Tad A Holak; Sushant P Kale; Kosmas Kosmas; Angelika A Noegel
Ablation of cyclase-associated protein 2 (CAP2) leads to cardiomyopathy.
Cellular and molecular life sciences : CMLS 2013;70(3):527-43.
2012: Yulia Artemenko; Petros Batsios; Jane Borleis; Zachary Gagnon; Josephine Lee; Meino Rohlfs; Doriane Sanséau; Michael Schleicher; Stacey S Willard; Peter N Devreotes
Tumor suppressor Hippo/MST1 kinase mediates chemotaxis by regulating spreading and adhesion.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(34):13632-7.
2012: Hameeda Sultana; Rosemarie Blau-Wasser; G Neelakanta; Francisco Rivero; Michael Schleicher; Angelika A Noegel
Ectopic expression of cyclase associated protein CAP restores the streaming and aggregation defects of adenylyl cyclase a deficient Dictyostelium discoideum cells.
BMC developmental biology 2012;12():3.
2011: Tomasz Sitar; Kathleen M Trybus; Michael Wohlhoefler; Andreas R Bausch; Anna M Ducka; Julia Gallinger; Robert Huber; Teemu P Ikonen; Peteranne Joel; Angelika A Noegel; Michael Schleicher; Kurt M Schmoller; Tad A Holak
Molecular architecture of the Spire-actin nucleus and its implication for actin filament assembly.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(49):19575-80.
2011: Andrew J Heidel; Nicholas R Helps; Uwe John; Hajara M Lawal; Angelika A Noegel; Matthias Platzer; Francisco Rivero; Pauline Schaap; Christina Schilde; Michael Schleicher; Budi Tunggal; Ludwig Eichinger; Marius Felder; Gernot Glöckner
Phylogeny-wide analysis of social amoeba genomes highlights ancient origins for complex intercellular communication.
Genome research 2011;21(11):1882-91.
2011: Peter M Kastner; Michael Schleicher; Annette Müller-Taubenberger
The NDR family kinase NdrA of Dictyostelium localizes to the centrosome and is required for efficient phagocytosis.
Traffic (Copenhagen, Denmark) 2011;12(3):301-12.
2011: Maria C Shina; Annette Müller-Taubenberger; Can Unal; Michael Schleicher; Michael Steinert; Ludwig Eichinger; Rolf Müller; Rosemarie Blau-Wasser; Gernot Glöckner; Angelika A Noegel
Redundant and unique roles of coronin proteins in Dictyostelium.
Cellular and molecular life sciences : CMLS 2011;68(2):303-13.
2010: Anna M Ducka; Peteranne Joel; Grzegorz M Popowicz; Kathleen M Trybus; Michael Schleicher; Angelika A Noegel; Robert Huber; Tad A Holak; Tomasz Sitar
Structures of actin-bound Wiskott-Aldrich syndrome protein homology 2 (WH2) domains of Spire and the implication for filament nucleation.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(26):11757-62.
2010: Maria C Shina; Can Unal; Ludwig Eichinger; Annette Müller-Taubenberger; Michael Schleicher; Michael Steinert; Angelika A Noegel
A Coronin7 homolog with functions in actin-driven processes.
The Journal of biological chemistry 2010;285(12):9249-61.
2010: Subhanjan Mondal; Bhagyashri Burgute; Daniela Rieger; Rolf Müller; Francisco Rivero; Jan Faix; Michael Schleicher; Angelika A Noegel
Regulation of the actin cytoskeleton by an interaction of IQGAP related protein GAPA with filamin and cortexillin I.
PloS one 2010;5(11):e15440.
2010: Maria Christina Shina; Rolf Müller; Rosemarie Blau-Wasser; Gernot Glöckner; Michael Schleicher; Ludwig Eichinger; Angelika A Noegel; Waldemar Kolanus
A cytohesin homolog in Dictyostelium amoebae.
PloS one 2010;5(2):e9378.
2009: Rosemarie Blau-Wasser; Ursula Euteneuer; Huajiang Xiong; Berthold Gassen; Michael Schleicher; Angelika A Noegel
CP250, a novel acidic coiled-coil protein of the Dictyostelium centrosome, affects growth, chemotaxis, and the nuclear envelope.
Molecular biology of the cell 2009;20(20):4348-61.
2008: Jayabalan M Joseph; Petra Fey; Nagendran Ramalingam; Xiao I Liu; Meino Rohlfs; Angelika A Noegel; Annette Müller-Taubenberger; Gernot Glöckner; Michael Schleicher
The actinome of Dictyostelium discoideum in comparison to actins and actin-related proteins from other organisms.
PloS one 2008;3(7):e2654.
2007: Meino Rohlfs; Rajesh Arasada; Petros Batsios; Julia Janzen; Michael Schleicher
The Ste20-like kinase SvkA of Dictyostelium discoideum is essential for late stages of cytokinesis.
Journal of cell science 2007;120(Pt 24):4345-54.
2007: V Peche; S Shekar; M Leichter; H Korte; Rolf Schröder; Michael Schleicher; T A Holak; Christoph S Clemen; B Ramanath-Y; Gabriele Pfitzer; Iakowos Karakesisoglou; Angelika A Noegel
CAP2, cyclase-associated protein 2, is a dual compartment protein.
Cellular and molecular life sciences : CMLS 2007;64(19-20):2702-15.
2007: Rajesh Arasada; Annika Gloss; Budi Tunggal; Jayabalan M Joseph; Daniela Rieger; Subhanjan Mondal; Jan Faix; Michael Schleicher; Angelika A Noegel
Profilin isoforms in Dictyostelium discoideum.
Biochimica et biophysica acta 2007;1773(5):631-41.
2007: Claudia Trasak; Gerhardt Zenner; Annette Vogel; Gülnihal Yüksekdag; René Rost; Ilka Haase; Markus Fischer; Lars Israel; Axel imhof; Stefan Linder; Michael Schleicher; Martin Aepfelbacher
Yersinia protein kinase YopO is activated by a novel G-actin binding process.
The Journal of biological chemistry 2007;282(4):2268-77.
2007: Nandkumar Khaire; Rolf Müller; Rosemarie Blau-Wasser; Ludwig Eichinger; Michael Schleicher; Matthias Rief; Tad A Holak; Angelika A Noegel
Filamin-regulated F-actin assembly is essential for morphogenesis and controls phototaxis in Dictyostelium.
The Journal of biological chemistry 2007;282(3):1948-55.
2006: Rajesh Arasada; Hyunju Son; Nagendran Ramalingam; Ludwig Eichinger; Michael Schleicher; Meino Rohlfs
Characterization of the Ste20-like kinase Krs1 of Dictyostelium discoideum.
European journal of cell biology 2006;85(9-10):1059-68.
2006: Axel Strehle; Michael Schleicher; Jan Faix
Trix, a novel Rac guanine-nucleotide exchange factor from Dictyostelium discoideum is an actin-binding protein and accumulates at endosomes.
European journal of cell biology 2006;85(9-10):1035-45.
2006: Marija Marko; Yogikala Prabhu; Rolf Müller; Rosemarie Blau-Wasser; Michael Schleicher; Angelika A Noegel
The annexins of Dictyostelium.
European journal of cell biology 2006;85(9-10):1011-22.
2006: Grzegorz M Popowicz; Michael Schleicher; Angelika A Noegel; Tad A Holak
Filamins: promiscuous organizers of the cytoskeleton.
Trends in biochemical sciences 2006;31(7):411-9.
2006: Antje Schirenbeck; Rajesh Arasada; Till Bretschneider; Theresia E B Stradal; Michael Schleicher; Jan Faix
The bundling activity of vasodilator-stimulated phosphoprotein is required for filopodium formation.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(20):7694-9.
2006: Patrick Farbrother; Carina Wagner; Jianbo Na; Budi Tunggal; Takahiro Morio; Hideko Urushihara; Yoshimasa Tanaka; Michael Schleicher; Michael Steinert; Ludwig Eichinger
Dictyostelium transcriptional host cell response upon infection with Legionella.
Cellular microbiology 2006;8(3):438-56.
2005: Antje Schirenbeck; Rajesh Arasada; Till Bretschneider; Michael Schleicher; Jan Faix
Formins and VASPs may co-operate in the formation of filopodia.
Biochemical Society transactions 2005;33(Pt 6):1256-9.
2005: Hameeda Sultana; Francisco Rivero; Rosemarie Blau-Wasser; Stephan Schwager; Alessandra Balbo; Salvatore Bozzaro; Michael Schleicher; Angelika A Noegel
Cyclase-associated protein is essential for the functioning of the endo-lysosomal system and provides a link to the actin cytoskeleton.
Traffic (Copenhagen, Denmark) 2005;6(10):930-46.
2005: Antje Schirenbeck; Till Bretschneider; Rajesh Arasada; Michael Schleicher; Jan Faix
The Diaphanous-related formin dDia2 is required for the formation and maintenance of filopodia.
Nature cell biology 2005;7(6):619-25.
2005: Ingo Schwaiger; Michael Schleicher; Angelika A Noegel; Matthias Rief
The folding pathway of a fast-folding immunoglobulin domain revealed by single-molecule mechanical experiments.
EMBO reports 2005;6(1):46-51.
2004: Monika Knuth; Nandkumar Khaire; Adam Kuspa; Si Jie Lu; Michael Schleicher; Angelika A Noegel
A novel partner for Dictyostelium filamin is an alpha-helical developmentally regulated protein.
Journal of cell science 2004;117(Pt 21):5013-22.
2004: Grzegorz M Popowicz; Rolf Müller; Angelika A Noegel; Michael Schleicher; Robert Huber; Tad A Holak
Molecular structure of the rod domain of dictyostelium filamin.
Journal of molecular biology 2004;342(5):1637-46.
2004: Marcela Fajardo; Michael Schleicher; Angelika A Noegel; Salvatore Bozzaro; Silke Killinger; Klaus Heuner; Jörg Hacker; Michael Steinert
Calnexin, calreticulin and cytoskeleton-associated proteins modulate uptake and growth of Legionella pneumophila in Dictyostelium discoideum.
Microbiology (Reading, England) 2004;150(Pt 9):2825-35.
2004: Chrystelle Mavoungou; Lars Israel; Till Rehm; Dorota Ksiazek; Marcin Krajewski; Grzegorz M Popowicz; Angelika A Noegel; Michael Schleicher; Tad A Holak
NMR structural characterization of the N-terminal domain of the adenylyl cyclase-associated protein (CAP) from Dictyostelium discoideum.
Journal of biomolecular NMR 2004;29(1):73-84.
2004: Angelika A Noegel; Rosemarie Blau-Wasser; Hameeda Sultana; Rolf Müller; Lars Israel; Michael Schleicher; Hitesh Patel; Cornelis J Weijer
The cyclase-associated protein CAP as regulator of cell polarity and cAMP signaling in Dictyostelium.
Molecular biology of the cell 2004;15(2):934-45.
2004: Jan Faix; Lisa Kreppel; Gad Shaulsky; Michael Schleicher; Alan R Kimmel
A rapid and efficient method to generate multiple gene disruptions in Dictyostelium discoideum using a single selectable marker and the Cre-loxP system.
Nucleic acids research 2004;32(19):e143.
2004: Ingo Schwaiger; Angelika Kardinal; Michael Schleicher; Angelika A Noegel; Matthias Rief
A mechanical unfolding intermediate in an actin-crosslinking protein.
Nature structural & molecular biology 2004;11(1):81-5.
2003: Dorota Ksiazek; Hans Brandstetter; Lars Israel; Gleb P Bourenkov; Galina Katchalova; Klaus-Peter Janssen; Hans D Bartunik; Angelika A Noegel; Michael Schleicher; Tad A Holak
Structure of the N-terminal domain of the adenylyl cyclase-associated protein (CAP) from Dictyostelium discoideum.
Structure (London, England : 1993) 2003;11(9):1171-8.
2003: Claudia Herr; Christoph S Clemen; Gisela Lehnert; Rüdiger Kutschkow; Susanne M Picker; Birgit S Gathof; Carlotta Zamparelli; Michael Schleicher; Angelika A Noegel
Function, expression and localization of annexin A7 in platelets and red blood cells: insights derived from an annexin A7 mutant mouse.
BMC biochemistry 2003;4():8.
2003: Annika Gloss; Francisco Rivero; Nandkumar Khaire; Rolf Müller; William F Loomis; Michael Schleicher; Angelika A Noegel
Villidin, a novel WD-repeat and villin-related protein from Dictyostelium, is associated with membranes and the cytoskeleton.
Molecular biology of the cell 2003;14(7):2716-27.
2002: Thomas Schreiner; Martina R Mohrs; Rosemarie Blau-Wasser; Alfred von Krempelhuber; Michael Steinert; Michael Schleicher; Angelika A Noegel
Loss of the F-actin binding and vesicle-associated protein comitin leads to a phagocytosis defect.
Eukaryotic cell 2002;1(6):906-14.
2002: Till Rehm; Chrystelle Mavoungou; Lars Israel; Michael Schleicher; Tad A Holak
Sequence-specific (1H, 15N, 13C) resonance assignment of the N-terminal domain of the cyclase-associated protein (CAP) from Dictyostelium discoideum.
Journal of biomolecular NMR 2002;23(4):337-8.
2002: Christian Renner; Michael Schleicher; Luis Moroder; Tad A Holak
Practical aspects of the 2D 15N-[1h]-NOE experiment.
Journal of biomolecular NMR 2002;23(1):23-33.
2002: Carina Skriwan; Marcela Fajardo; Sonja Hägele; Matthias Horn; Michael Wagner; Rolf Michel; Georg Krohne; Michael Schleicher; Jörg Hacker; Michael Steinert
Various bacterial pathogens and symbionts infect the amoeba Dictyostelium discoideum.
International journal of medical microbiology : IJMM 2002;291(8):615-24.
2001: KP Janssen; R Rost; Ludwig Eichinger; Michael Schleicher
Characterization of CD36/LIMPII homologues in Dictyostelium discoideum.
The Journal of biological chemistry 2001;276(42):38899-910.
2001: KP Janssen; Michael Schleicher
Dictyostelium discoideum: a genetic model system for the study of professional phagocytes. Profilin, phosphoinositides and the lmp gene family in Dictyostelium.
Biochimica et biophysica acta 2001;1525(3):228-33.
2001: Thomas P Stossel; John Condeelis; L Cooley; John H Hartwig; A Noegel; Michael Schleicher; S S Shapiro
Filamins as integrators of cell mechanics and signalling.
Nature reviews. Molecular cell biology 2001;2(2):138-45.
2000: Lesly A Temesvari; L Zhang; B Fodera; K P Janssen; Michael Schleicher; J A Cardelli
Inactivation of lmpA, encoding a LIMPII-related endosomal protein, suppresses the internalization and endosomal trafficking defects in profilin-null mutants.
Molecular biology of the cell 2000;11(6):2019-31.
2000: Yoram A Puius; Elena V Fedorov; Ludwig Eichinger; Michael Schleicher; Steven C Almo
Mapping the functional surface of domain 2 in the gelsolin superfamily.
Biochemistry 2000;39(18):5322-31.
2000: M R Mohrs; K P Janssen; T Kreis; Angelika A Noegel; Michael Schleicher
Cloning and characterization of beta-COP from Dictyostelium discoideum.
European journal of cell biology 2000;79(5):350-7.
2000: Sonja Hägele; Rolf Köhler; H Merkert; Michael Schleicher; Jörg Hacker; Michael Steinert
Dictyostelium discoideum: a new host model system for intracellular pathogens of the genus Legionella.
Cellular microbiology 2000;2(2):165-71.
2000: Angelika A Noegel; Michael Schleicher
The actin cytoskeleton of Dictyostelium: a story told by mutants.
Journal of cell science 2000;113 ( Pt 5)():759-66.
2000: S S Lee; Iakowos Karakesisoglou; Angelika A Noegel; D Rieger; Michael Schleicher
Dissection of functional domains by expression of point-mutated profilins in Dictyostelium mutants.
European journal of cell biology 2000;79(2):92-103.
1999: Ludwig Eichinger; S S Lee; Michael Schleicher
Dictyostelium as model system for studies of the actin cytoskeleton by molecular genetics.
Microscopy research and technique 1999;47(2):124-34.
1999: Angelika A Noegel; Francisco Rivero; R Albrecht; K P Janssen; J Köhler; C A Parent; Michael Schleicher
Assessing the role of the ASP56/CAP homologue of Dictyostelium discoideum and the requirements for subcellular localization.
Journal of cell science 1999;112 ( Pt 19)():3195-203.
1999: P Fucini; B Köppel; Michael Schleicher; A Lustig; Tad A Holak; R Müller; Murray Stewart; Angelika A Noegel
Molecular architecture of the rod domain of the Dictyostelium gelation factor (ABP120).
Journal of molecular biology 1999;291(5):1017-23.
1999: Stefan Steinbacher; Patrick R Hof; Ludwig Eichinger; Michael Schleicher; Jan Gettemans; Joël Vandekerckhove; Robert Huber; J Benz
The crystal structure of the Physarum polycephalum actin-fragmin kinase: an atypical protein kinase with a specialized substrate-binding domain.
The EMBO journal 1999;18(11):2923-9.
1999: Iakowos Karakesisoglou; KP Janssen; Ludwig Eichinger; Angelika A Noegel; Michael Schleicher
Identification of a suppressor of the Dictyostelium profilin-minus phenotype as a CD36/LIMP-II homologue.
The Journal of cell biology 1999;145(1):167-81.
1998: M Grummt; Günther Woehlke; U Henningsen; S Fuchs; Michael Schleicher; Manfred Schliwa
Importance of a flexible hinge near the motor domain in kinesin-driven motility.
The EMBO journal 1998;17(19):5536-42.
1998: Ludwig Eichinger; Martin Bähler; M Dietz; Christoph Eckerskorn; Michael Schleicher
Characterization and cloning of a Dictyostelium Ste20-like protein kinase that phosphorylates the actin-binding protein severin.
The Journal of biological chemistry 1998;273(21):12952-9.
1997: P Fucini; Airlie J McCoy; M Gomez-Ortiz; Michael Schleicher; Angelika A Noegel; Murray Stewart
Crystallization and preliminary X-Ray diffraction characterization of a dimerizing fragment of the rod domain of the Dictyostelium gelation factor (ABP-120).
Journal of structural biology 1997;120(2):192-5.
1996: Francisco Rivero; B Köppel; Barbara Peracino; Salvatore Bozzaro; F Siegert; Cornelis J Weijer; Michael Schleicher; Ronald Albrecht; Angelika A Noegel
The role of the cortical cytoskeleton: F-actin crosslinking proteins protect against osmotic stress, ensure cell size, cell shape and motility, and contribute to phagocytosis and development.
Journal of cell science 1996;109 ( Pt 11)():2679-91.
1996: Ludwig Eichinger; L Bomblies; J Vandekerckhove; Michael Schleicher; J Gettemans
A novel type of protein kinase phosphorylates actin in the actin-fragmin complex.
The EMBO journal 1996;15(20):5547-56.
1996: M Stoeckelhuber; Angelika A Noegel; C Eckerskorn; J Köhler; D Rieger; Michael Schleicher
Structure/function studies on the pH-dependent actin-binding protein hisactophilin in Dictyostelium mutants.
Journal of cell science 1996;109 ( Pt 7)():1825-35.
1996: E Jung; P Fucini; Murray Stewart; Angelika A Noegel; Michael Schleicher
Linking microfilaments to intracellular membranes: the actin-binding and vesicle-associated protein comitin exhibits a mannose-specific lectin activity.
The EMBO journal 1996;15(6):1238-46.
1996: B André; A A Noegel; Michael Schleicher
Dictyostelium discoideum contains a family of calmodulin-related EF-hand proteins that are developmentally regulated.
FEBS letters 1996;382(1-2):198-202.
1996: Ludwig Eichinger; B Köppel; Angelika A Noegel; Michael Schleicher; Manfred Schliwa; K Weijer; W Witke; P A Janmey
Mechanical perturbation elicits a phenotypic difference between Dictyostelium wild-type cells and cytoskeletal mutants.
Biophysical journal 1996;70(2):1054-60.
1996: U Gottwald; R Brokamp; I Karakesisoglou; Michael Schleicher; Angelika A Noegel
Identification of a cyclase-associated protein (CAP) homologue in Dictyostelium discoideum and characterization of its interaction with actin.
Molecular biology of the cell 1996;7(2):261-72.
1996: K P Janssen; Ludwig Eichinger; P A Janmey; Angelika A Noegel; Manfred Schliwa; W Witke; Michael Schleicher
Viscoelastic properties of F-actin solutions in the presence of normal and mutated actin-binding proteins.
Archives of biochemistry and biophysics 1996;325(2):183-9.
1996: I Karakesisoglou; Michael Schleicher; BC Gibbon; Christopher J Staiger
Plant profilins rescue the aberrant phenotype of profilin-deficient Dictyostelium cells.
Cell motility and the cytoskeleton 1996;34(1):36-47.
1995: U Röhrig; Günther Gerisch; L Morozova; Michael Schleicher; A Wegner
Coactosin interferes with the capping of actin filaments.
FEBS letters 1995;374(2):284-6.
1995: Michael Schleicher; B André; C Andréoli; Ludwig Eichinger; M Haugwitz; A Hofmann; J Karakesisoglou; M Stöckelhuber; Angelika A Noegel
Structure/function studies on cytoskeletal proteins in Dictyostelium amoebae as a paradigm.
FEBS letters 1995;369(1):38-42.
1995: V Döring; F Veretout; Ronald Albrecht; B Mühlbauer; C Schlatterer; Michael Schleicher; Angelika A Noegel
The in vivo role of annexin VII (synexin): characterization of an annexin VII-deficient Dictyostelium mutant indicates an involvement in Ca(2+)-regulated processes.
Journal of cell science 1995;108 ( Pt 5)():2065-76.
1995: A Schnuchel; R Wiltscheck; Ludwig Eichinger; Michael Schleicher; Tad A Holak
Structure of severin domain 2 in solution.
Journal of molecular biology 1995;247(1):21-7.
1994: M Haugwitz; Angelika A Noegel; J Karakesisoglou; Michael Schleicher
Dictyostelium amoebae that lack G-actin-sequestering profilins show defects in F-actin content, cytokinesis, and development.
Cell 1994;79(2):303-14.
1993: O H Weiner; J Murphy; G Griffiths; Michael Schleicher; Angelika A Noegel
The actin-binding protein comitin (p24) is a component of the Golgi apparatus.
The Journal of cell biology 1993;123(1):23-34.
1993: U Haus; P Trommler; Paul R Fisher; H Hartmann; Friedrich Lottspeich; Angelika A Noegel; Michael Schleicher
The heat shock cognate protein from Dictyostelium affects actin polymerization through interaction with the actin-binding protein cap32/34.
The EMBO journal 1993;12(10):3763-71.
1993: A Hofmann; Angelika A Noegel; L Bomblies; Friedrich Lottspeich; Michael Schleicher
The 100 kDa F-actin capping protein of Dictyostelium amoebae is a villin prototype ('protovillin').
FEBS letters 1993;328(1-2):71-6.
1993: W Witke; A Hofmann; B Köppel; Michael Schleicher; Angelika A Noegel
The Ca(2+)-binding domains in non-muscle type alpha-actinin: biochemical and genetic analysis.
The Journal of cell biology 1993;121(3):599-606.
1992: J Habazettl; Michael Schleicher; Jacek Otlewski; Tad A Holak
Homonuclear three-dimensional NOE-NOE nuclear magnetic resonance/spectra for structure determination of proteins in solution.
Journal of molecular biology 1992;228(1):156-69.
1992: J Habazettl; D Gondol; R Wiltscheck; Jacek Otlewski; Michael Schleicher; Tad A Holak
Structure of hisactophilin is similar to interleukin-1 beta and fibroblast growth factor.
Nature 1992;359(6398):855-8.
1992: Ludwig Eichinger; Michael Schleicher
Characterization of actin- and lipid-binding domains in severin, a Ca(2+)-dependent F-actin fragmenting protein.
Biochemistry 1992;31(20):4779-87.
1992: Michael Schleicher; Angelika A Noegel
Dynamics of the Dictyostelium cytoskeleton during chemotaxis.
The New biologist 1992;4(5):461-72.
1992: W Witke; Michael Schleicher; Angelika A Noegel
Redundancy in the microfilament system: abnormal development of Dictyostelium cells lacking two F-actin cross-linking proteins.
Cell 1992;68(1):53-62.
1992: A Hofmann; Ludwig Eichinger; E André; D Rieger; Michael Schleicher
Cap100, a novel phosphatidylinositol 4,5-bisphosphate-regulated protein that caps actin filaments but does not nucleate actin assembly.
Cell motility and the cytoskeleton 1992;23(2):133-44.
1991: U Haus; H Hartmann; P Trommler; Angelika A Noegel; Michael Schleicher
F-actin capping by cap32/34 requires heterodimeric conformation and can be inhibited with PIP2.
Biochemical and biophysical research communications 1991;181(2):833-9.
1991: M Haugwitz; Angelika A Noegel; D Rieger; Friedrich Lottspeich; Michael Schleicher
Dictyostelium discoideum contains two profilin isoforms that differ in structure and function.
Journal of cell science 1991;100 ( Pt 3)():481-9.
1991: V Döring; Michael Schleicher; Angelika A Noegel
Dictyostelium annexin VII (synexin). cDNA sequence and isolation of a gene disruption mutant.
The Journal of biological chemistry 1991;266(26):17509-15.
1991: L Wiesmüller; J Wittbrodt; Angelika A Noegel; Michael Schleicher
Purification and cDNA-derived sequence of adenylosuccinate synthetase from Dictyostelium discoideum.
The Journal of biological chemistry 1991;266(4):2480-5.
1991: Angelika A Noegel; Michael Schleicher
Phenotypes of cells with cytoskeletal mutations.
Current opinion in cell biology 1991;3(1):18-26.
1991: Ludwig Eichinger; Angelika A Noegel; Michael Schleicher
Domain structure in actin-binding proteins: expression and functional characterization of truncated severin.
The Journal of cell biology 1991;112(4):665-76.
1990: M Brink; Günther Gerisch; G Isenberg; Angelika A Noegel; Jeffrey E Segall; E Wallraff; Michael Schleicher
A Dictyostelium mutant lacking an F-actin cross-linking protein, the 120-kD gelation factor.
The Journal of cell biology 1990;111(4):1477-89.
1990: D Lück-Vielmetter; Michael Schleicher; B Grabatin; J Wippler; Günther Gerisch
Replacement of threonine residues by serine and alanine in a phosphorylatable heavy chain fragment of Dictyostelium myosin II.
FEBS letters 1990;269(1):239-43.
1990: Angelika A Noegel; Günther Gerisch; Friedrich Lottspeich; Michael Schleicher
A protein with homology to the C-terminal repeat sequence of Octopus rhodopsin and synaptophysin is a member of a multigene family in Dictyostelium discoideum.
FEBS letters 1990;266(1-2):118-22.
1990: L Wiesmüller; Angelika A Noegel; Octavian Bârzu; Günther Gerisch; Michael Schleicher
cDNA-derived sequence of UMP-CMP kinase from Dictyostelium discoideum and expression of the enzyme in Escherichia coli.
The Journal of biological chemistry 1990;265(11):6339-45.
1990: L Bomblies; E Biegelmann; V Döring; Günther Gerisch; H Krafft-Czepa; Angelika A Noegel; Michael Schleicher; B M Humbel
Membrane-enclosed crystals in Dictyostelium discoideum cells, consisting of developmentally regulated proteins with sequence similarities to known esterases.
The Journal of cell biology 1990;110(3):669-79.
1990: Michael Schleicher; Ludwig Eichinger; W Witke; Angelika A Noegel
Ca2(+)-binding proteins as components of the cytoskeleton.
Advances in experimental medicine and biology 1990;269():99-102.
1990: H Hartmann; Michael Schleicher; Angelika A Noegel
Heterodimeric capping proteins constitute a highly conserved group of actin-binding proteins.
Developmental genetics 1990;11(5-6):369-76.
1989: A A Noegel; S Rapp; F Lottspeich; Michael Schleicher; M Stewart
The Dictyostelium gelation factor shares a putative actin binding site with alpha-actinins and dystrophin and also has a rod domain containing six 100-residue motifs that appear to have a cross-beta conformation.
The Journal of cell biology 1989;109(2):607-18.
1989: H Hartmann; Angelika A Noegel; C Eckerskorn; S Rapp; Michael Schleicher
Ca2+-independent F-actin capping proteins. Cap 32/34, a capping protein from Dictyostelium discoideum, does not share sequence homologies with known actin-binding proteins.
The Journal of biological chemistry 1989;264(21):12639-47.
1989: Annette Müller-Taubenberger; Hanns-Rüdiger Graack; L Grohmann; Michael Schleicher; Günther Gerisch
An extended ubiquitin of Dictyostelium is located in the small ribosomal subunit.
The Journal of biological chemistry 1989;264(10):5319-22.
1989: E André; M Brink; Günther Gerisch; G Isenberg; Angelika A Noegel; Michael Schleicher; Jeffrey E Segall; E Wallraff
A Dictyostelium mutant deficient in severin, an F-actin fragmenting protein, shows normal motility and chemotaxis.
The Journal of cell biology 1989;108(3):985-95.
1989: J Scheel; K Ziegelbauer; T Kupke; B M Humbel; Angelika A Noegel; Günther Gerisch; Michael Schleicher
Hisactophilin, a histidine-rich actin-binding protein from Dictyostelium discoideum.
The Journal of biological chemistry 1989;264(5):2832-9.
1989: Angelika A Noegel; B Leiting; W Witke; C Gurniak; C Harloff; H Hartmann; E Wiesmüller; Michael Schleicher
Biological roles of actin-binding proteins in Dictyostelium discoideum examined using genetic techniques.
Cell motility and the cytoskeleton 1989;14(1):69-74.
1988: Michael Schleicher; Angelika A Noegel; T Schwarz; E Wallraff; M Brink; Jan Faix; Günther Gerisch; G Isenberg
A Dictyostelium mutant with severe defects in alpha-actinin: its characterization using cDNA probes and monoclonal antibodies.
Journal of cell science 1988;90 ( Pt 1)():59-71.
1988: E André; Friedrich Lottspeich; Michael Schleicher; Angelika A Noegel
Severin, gelsolin, and villin share a homologous sequence in regions presumed to contain F-actin severing domains.
The Journal of biological chemistry 1988;263(2):722-7.
1988: Michael Schleicher; E André; H Hartmann; Angelika A Noegel
Actin-binding proteins are conserved from slime molds to man.
Developmental genetics 1988;9(4-5):521-30.
1987: Angelika A Noegel; W Witke; Michael Schleicher
Calcium-sensitive non-muscle alpha-actinin contains EF-hand structures and highly conserved regions.
FEBS letters 1987;221(2):391-6.
1986: W Witke; Michael Schleicher; F Lottspeich; Angelika A Noegel
Studies on the transcription, translation, and structure of alpha-actinin in Dictyostelium discoideum.
The Journal of cell biology 1986;103(3):969-75.
1986: E Wallraff; Michael Schleicher; M Modersitzki; D Rieger; G Isenberg; Günther Gerisch
Selection of Dictyostelium mutants defective in cytoskeletal proteins: use of an antibody that binds to the ends of alpha-actinin rods.
The EMBO journal 1986;5(1):61-7.