Timothy Blackwell

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Connelly Linda; Barham Whitney; Pigg Rachel; Saint-Jean Leshana; Sherrill Taylor; Cheng Dong-Sheng; Chodosh Lewis A; Blackwell Timothy S; Yull Fiona E
Activation of nuclear factor kappa B in mammary epithelium promotes milk loss during mammary development and infection.
Tanjore Harikrishna; Xu Xiaochuan C; Polosukhin Vasiliy V; Degryse Amber L; Li Bo; Han Wei; Sherrill Taylor P; Plieth David; Neilson Eric G; Blackwell Timothy S; Lawson William E
Contribution of epithelial-derived fibroblasts to bleomycin-induced lung fibrosis.
Ma Lian-Li; Gao Xiudan; Liu Liping; Xiang Zhidan; Blackwell Timothy S; Williams Philip; Chari Ravi S; Yin Deng-Ping
CpG oligodeoxynucleotide triggers the liver inflammatory reaction and abrogates spontaneous tolerance.

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2010: Connelly Linda; Barham Whitney; Pigg Rachel; Saint-Jean Leshana; Sherrill Taylor; Cheng Dong-Sheng; Chodosh Lewis A; Blackwell Timothy S; Yull Fiona E
Activation of nuclear factor kappa B in mammary epithelium promotes milk loss during mammary development and infection.
Journal of cellular physiology 2010;222(1):73-81.
2009: Tanjore Harikrishna; Xu Xiaochuan C; Polosukhin Vasiliy V; Degryse Amber L; Li Bo; Han Wei; Sherrill Taylor P; Plieth David; Neilson Eric G; Blackwell Timothy S; Lawson William E
Contribution of epithelial-derived fibroblasts to bleomycin-induced lung fibrosis.
American journal of respiratory and critical care medicine 2009;180(7):657-65.
2009: Ma Lian-Li; Gao Xiudan; Liu Liping; Xiang Zhidan; Blackwell Timothy S; Williams Philip; Chari Ravi S; Yin Deng-Ping
CpG oligodeoxynucleotide triggers the liver inflammatory reaction and abrogates spontaneous tolerance.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2009;15(8):915-23.
2009: Bastarache Julie A; Blackwell Timothy S
Development of animal models for the acute respiratory distress syndrome.
Disease models & mechanisms 2009;2(5-6):218-23.
2009: Joo Myungsoo; Kwon Minjae; Cho Yong-Jig; Hu Ningning; Pedchenko Tetyana V; Sadikot Ruxana T; Blackwell Timothy S; Christman John W
Lipopolysaccharide-dependent interaction between PU.1 and c-Jun determines production of lipocalin-type prostaglandin D synthase and prostaglandin D2 in macrophages.
American journal of physiology. Lung cellular and molecular physiology 2009;296(5):L771-9.
2009: Han Wei; Joo Myungsoo; Everhart M Brett; Christman John W; Yull Fiona E; Blackwell Timothy S
Myeloid cells control termination of lung inflammation through the NF-kappaB pathway.
American journal of physiology. Lung cellular and molecular physiology 2009;296(3):L320-7.
2009: Sadagopal Shanmugalakshmi; Braunstein Miriam; Hager Cynthia C; Wei Jie; Daniel Alexandria K; Bochan Markian R; Crozier Ian; Smith Nathaniel E; Gates Hiriam O; Barnett Louise; Van Kaer Luc; Price James O; Blackwell Timothy S; Kalams Spyros A; Kernodle Douglas S
Reducing the activity and secretion of microbial antioxidants enhances the immunogenicity of BCG.
PloS one 2009;4(5):e5531.
2008: Stathopoulos Georgios T; Psallidas Ioannis; Moustaki Ardiana; Moschos Charalampos; Kollintza Androniki; Karabela Sophia; Porfyridis Ilias; Vassiliou Spyridoula; Karatza Marilena; Zhou Zongmin; Joo Myungsoo; Blackwell Timothy S; Roussos Charis; Graf Daniel; Kalomenidis Ioannis
A central role for tumor-derived monocyte chemoattractant protein-1 in malignant pleural effusion.
Journal of the National Cancer Institute 2008;100(20):1464-76.
2008: Chen S M; Cheng D-S; Williams B J; Sherrill T P; Han W; Chont M; Saint-Jean L; Christman J W; Sadikot R T; Yull F E; Blackwell T S
The nuclear factor kappa-B pathway in airway epithelium regulates neutrophil recruitment and host defence following Pseudomonas aeruginosa infection.
Clinical and experimental immunology 2008;153(3):420-8.
2008: Jin Ren Jie; Lho Yongsoo; Connelly Linda; Wang Yongqing; Yu Xiuping; Saint Jean Leshana; Case Thomas C; Ellwood-Yen Katharine; Sawyers Charles L; Bhowmick Neil A; Blackwell Timothy S; Yull Fiona E; Matusik Robert J
The nuclear factor-kappaB pathway controls the progression of prostate cancer to androgen-independent growth.
Cancer research 2008;68(16):6762-9.
2008: Musiek Erik S; Brooks Joshua D; Joo Myungsoo; Brunoldi Enrico; Porta Alessio; Zanoni Giuseppe; Vidari Giovanni; Blackwell Timothy S; Montine Thomas J; Milne Ginger L; McLaughlin BethAnn; Morrow Jason D
Electrophilic cyclopentenone neuroprostanes are anti-inflammatory mediators formed from the peroxidation of the omega-3 polyunsaturated fatty acid docosahexaenoic acid.
The Journal of biological chemistry 2008;283(29):19927-35.
2008: Joo Myungsoo; Kwon Minjae; Azim Anser C; Sadikot Ruxana T; Blackwell Timothy S; Christman John W
Genetic determination of the role of PU.1 in macrophage gene expression.
Biochemical and biophysical research communications 2008;372(1):97-102.
2008: Lawson William E; Crossno Peter F; Polosukhin Vasiliy V; Roldan Juan; Cheng Dong-Sheng; Lane Kirk B; Blackwell Thomas R; Xu Carol; Markin Cheryl; Ware Lorraine B; Miller Geraldine G; Loyd James E; Blackwell Timothy S
Endoplasmic reticulum stress in alveolar epithelial cells is prominent in IPF: association with altered surfactant protein processing and herpesvirus infection.
American journal of physiology. Lung cellular and molecular physiology 2008;294(6):L1119-26.
2008: Ma Lianli; Xiang Zhidan; Sherrill Taylor P; Wang Lei; Blackwell Timothy S; Williams Philip; Chong Anita; Chari Ravi; Yin Deng Ping
Bioluminescence imaging visualizes activation of nuclear factor-kappaB in mouse cardiac transplantation.
Transplantation 2008;85(6):903-10.
2008: Stathopoulos Georgios T; Sherrill Taylor P; Han Wei; Sadikot Ruxana T; Yull Fiona E; Blackwell Timothy S; Fingleton Barbara
Host nuclear factor-kappaB activation potentiates lung cancer metastasis.
Molecular cancer research : MCR 2008;6(3):364-71.
2008: Tager Andrew M; LaCamera Peter; Shea Barry S; Campanella Gabriele S; Selman Moisés; Zhao Zhenwen; Polosukhin Vasiliy; Wain John; Karimi-Shah Banu A; Kim Nancy D; Hart William K; Pardo Annie; Blackwell Timothy S; Xu Yan; Chun Jerold; Luster Andrew D
The lysophosphatidic acid receptor LPA1 links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak.
Nature medicine 2008;14(1):45-54.
2008: Stathopoulos Georgios T; Sherrill Taylor P; Han Wei; Sadikot Ruxana T; Polosukhin Vasiliy V; Fingleton Barbara; Yull Fiona E; Blackwell Timothy S
Use of bioluminescent imaging to investigate the role of nuclear factor-kappaBeta in experimental non-small cell lung cancer metastasis.
Clinical & experimental metastasis 2008;25(1):43-51.
2007: Stathopoulos Georgios T; Sherrill Taylor P; Cheng Dong-Sheng; Scoggins Robert M; Han Wei; Polosukhin Vasiliy V; Connelly Linda; Yull Fiona E; Fingleton Barbara; Blackwell Timothy S
Epithelial NF-kappaB activation promotes urethane-induced lung carcinogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(47):18514-9.
2007: Park G Y; Hu N; Wang X; Sadikot R T; Yull F E; Joo M; Peebles R S; Blackwell T S; Christman J W
Conditional regulation of cyclooxygenase-2 in tracheobronchial epithelial cells modulates pulmonary immunity.
Clinical and experimental immunology 2007;150(2):245-54.
2007: Stathopoulos Georgios T; Kollintza Androniki; Moschos Charalampos; Psallidas Ioannis; Sherrill Taylor P; Pitsinos Emmanuel N; Vassiliou Spyridoula; Karatza Marilena; Papiris Spyros A; Graf Daniel; Orphanidou Dora; Light Richard W; Roussos Charis; Blackwell Timothy S; Kalomenidis Ioannis
Tumor necrosis factor-alpha promotes malignant pleural effusion.
Cancer research 2007;67(20):9825-34.
2007: Zhang Huimin; Lawson William E; Polosukhin Vasiliy V; Pozzi Ambra; Blackwell Timothy S; Litingtung Ying; Chiang Chin
Inhibitor of differentiation 1 promotes endothelial survival in a bleomycin model of lung injury in mice.
The American journal of pathology 2007;171(4):1113-26.
2007: Polosukhin Vasiliy V; Lawson William E; Milstone Aaron P; Egunova Svetlana M; Kulipanov Andrey G; Tchuvakin Sergey G; Massion Pierre P; Blackwell Timothy S
Association of progressive structural changes in the bronchial epithelium with subepithelial fibrous remodeling: a potential role for hypoxia.
Virchows Archiv : an international journal of pathology 2007;451(4):793-803.
2007: Joo Myungsoo; Kwon Minjae; Sadikot Ruxana T; Kingsley Philip J; Marnett Lawrence J; Blackwell Timothy S; Peebles R Stokes; Urade Yoshihiro; Christman John W
Induction and function of lipocalin prostaglandin D synthase in host immunity.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(4):2565-75.
2007: Cheng Dong-sheng; Han Wei; Chen Sabrina M; Sherrill Taylor P; Chont Melissa; Park Gye-Young; Sheller James R; Polosukhin Vasiliy V; Christman John W; Yull Fiona E; Blackwell Timothy S
Airway epithelium controls lung inflammation and injury through the NF-kappa B pathway.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(10):6504-13.
2007: Joo Myungsoo; Wright Jeffrey G; Hu Ning Ning; Sadikot Ruxana T; Park Gye Young; Blackwell Timothy S; Christman John W
Yin Yang 1 enhances cyclooxygenase-2 gene expression in macrophages.
American journal of physiology. Lung cellular and molecular physiology 2007;292(5):L1219-26.
2007: Sadikot Ruxana T; Zeng Heng; Azim Anser C; Joo Myungsoo; Dey Sudhansu K; Breyer Richard M; Peebles R Stokes; Blackwell Timothy S; Christman John W
Bacterial clearance of Pseudomonas aeruginosa is enhanced by the inhibition of COX-2.
European journal of immunology 2007;37(4):1001-9.
2007: Connelly Linda; Robinson-Benion Cheryl; Chont Melissa; Saint-Jean Leshana; Li Haijing; Polosukhin Vasiliy V; Blackwell Timothy S; Yull Fiona E
A transgenic model reveals important roles for the NF-kappa B alternative pathway (p100/p52) in mammary development and links to tumorigenesis.
The Journal of biological chemistry 2007;282(13):10028-35.
2007: Zhou Weisong; Blackwell Timothy S; Goleniewska Kasia; O'Neal Jamye F; Fitzgerald Garret A; Lucitt Margaret; Breyer Richard M; Peebles R Stokes
Prostaglandin I2 analogs inhibit Th1 and Th2 effector cytokine production by CD4 T cells.
Journal of leukocyte biology 2007;81(3):809-17.
2007: Kalomenidis Ioannis; Stathopoulos Georgios T; Barnette Randal; Papiris Spyros; Blackwell Timothy S; Roussos Charis; Light Richard W
Vascular endothelial growth factor levels in post-CABG pleural effusions are associated with pleural inflammation and permeability.
Respiratory medicine 2007;101(2):223-9.
2007: Zhou Weisong; Hashimoto Koichi; Goleniewska Kasia; O'Neal Jamye F; Ji Shaoquan; Blackwell Timothy S; Fitzgerald Garret A; Egan Karine M; Geraci Mark W; Peebles R Stokes
Prostaglandin I2 analogs inhibit proinflammatory cytokine production and T cell stimulatory function of dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(2):702-10.
2006: Gray Keith D; Simovic Misho O; Blackwell Timothy S; Christman John W; May Addison K; Parman Kelly S; Chapman William C; Stain Steven C
Activation of nuclear factor kappa B and severe hepatic necrosis may mediate systemic inflammation in choline-deficient/ethionine-supplemented diet-induced pancreatitis.
Pancreas 2006;33(3):260-7.
2006: Maus Ulrich A; Janzen Simeon; Wall Gerhard; Srivastava Mrigank; Blackwell Timothy S; Christman John W; Seeger Werner; Welte Tobias; Lohmeyer Jürgen
Resident alveolar macrophages are replaced by recruited monocytes in response to endotoxin-induced lung inflammation.
American journal of respiratory cell and molecular biology 2006;35(2):227-35.
2006: Park Gye Young; Wang Xuerong; Hu Ningning; Pedchenko Tetyana V; Blackwell Timothy S; Christman John W
NIK is involved in nucleosomal regulation by enhancing histone H3 phosphorylation by IKKalpha.
The Journal of biological chemistry 2006;281(27):18684-90.
2006: Everhart M Brett; Han Wei; Sherrill Taylor P; Arutiunov Melissa; Polosukhin Vasiliy V; Burke James R; Sadikot Ruxana T; Christman John W; Yull Fiona E; Blackwell Timothy S
Duration and intensity of NF-kappaB activity determine the severity of endotoxin-induced acute lung injury.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(8):4995-5005.
2006: Sadikot Ruxana T; Zeng Heng; Joo Myungsoo; Everhart M Brett; Sherrill Taylor P; Li Bo; Cheng Dong-sheng; Yull Fiona E; Christman John W; Blackwell Timothy S
Targeted immunomodulation of the NF-kappaB pathway in airway epithelium impacts host defense against Pseudomonas aeruginosa.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(8):4923-30.
2006: Stafforini Diana M; Sheller James R; Blackwell Timothy S; Sapirstein Adam; Yull Fiona E; McIntyre Thomas M; Bonventre Joseph V; Prescott Stephen M; Roberts L Jackson
Release of free F2-isoprostanes from esterified phospholipids is catalyzed by intracellular and plasma platelet-activating factor acetylhydrolases.
The Journal of biological chemistry 2006;281(8):4616-23.
2006: Stathopoulos Georgios T; Zhu Zhiwen; Everhart M Brett; Kalomenidis Ioannis; Lawson William E; Bilaceroglu Semra; Peterson Todd E; Mitchell Daphne; Yull Fiona E; Light Richard W; Blackwell Timothy S
Nuclear factor-kappaB affects tumor progression in a mouse model of malignant pleural effusion.
American journal of respiratory cell and molecular biology 2006;34(2):142-50.
2005: Lawson William E; Polosukhin Vasiliy V; Stathopoulos Georgios T; Zoia Ornella; Han Wei; Lane Kirk B; Li Bo; Donnelly Edwin F; Holburn George E; Lewis Kenneth G; Collins Robert D; Hull William M; Glasser Stephan W; Whitsett Jeffrey A; Blackwell Timothy S
Increased and prolonged pulmonary fibrosis in surfactant protein C-deficient mice following intratracheal bleomycin.
The American journal of pathology 2005;167(5):1267-77.
2005: Cheng Qiufang; Zhao Yong; Lawson William E; Polosukhin Vasiliy V; Johnson Joyce E; Blackwell Timothy S; Gailani David
The effects of intrinsic pathway protease deficiencies on plasminogen-deficient mice.
Blood 2005;106(9):3055-7.
2005: Musiek Erik S; Gao Ling; Milne Ginger L; Han Wei; Everhart M Brett; Wang Dingzhi; Backlund Michael G; DuBois Raymond N; Zanoni Giuseppe; Vidari Giovanni; Blackwell Timothy S; Morrow Jason D
Cyclopentenone isoprostanes inhibit the inflammatory response in macrophages.
The Journal of biological chemistry 2005;280(42):35562-70.
2005: O'Donnell Sean M; Hansberger Mark W; Connolly Jodi L; Chappell James D; Watson Melissa J; Pierce Janene M; Wetzel J Denise; Han Wei; Barton Erik S; Forrest J Craig; Valyi-Nagy Tibor; Yull Fiona E; Blackwell Timothy S; Rottman Jeffrey N; Sherry Barbara; Dermody Terence S
Organ-specific roles for transcription factor NF-kappaB in reovirus-induced apoptosis and disease.
The Journal of clinical investigation 2005;115(9):2341-50.
2005: Pedchenko Tetyana V; Park Gye Young; Joo Myungsoo; Blackwell Timothy S; Christman John W
Inducible binding of PU.1 and interacting proteins to the Toll-like receptor 4 promoter during endotoxemia.
American journal of physiology. Lung cellular and molecular physiology 2005;289(3):L429-37.
2005: Kalomenidis Ioannis; Stathopoulos Georgios T; Barnette Randal; Guo Yubiao; Peebles R Stokes; Blackwell Timothy S; Light Richard W
Eotaxin-3 and interleukin-5 pleural fluid levels are associated with pleural fluid eosinophilia in post-coronary artery bypass grafting pleural effusions.
Chest 2005;127(6):2094-100.
2005: Joo Myungsoo; Hahn Young S; Kwon Minjae; Sadikot Ruxana T; Blackwell Timothy S; Christman John W
Hepatitis C virus core protein suppresses NF-kappaB activation and cyclooxygenase-2 expression by direct interaction with IkappaB kinase beta.
Journal of virology 2005;79(12):7648-57.
2005: Sadikot Ruxana T; Blackwell Timothy S; Christman John W; Prince Alice S
Pathogen-host interactions in Pseudomonas aeruginosa pneumonia.
American journal of respiratory and critical care medicine 2005;171(11):1209-23.
2005: Lawson William E; Polosukhin Vasiliy V; Zoia Ornella; Stathopoulos Georgios T; Han Wei; Plieth David; Loyd James E; Neilson Eric G; Blackwell Timothy S
Characterization of fibroblast-specific protein 1 in pulmonary fibrosis.
American journal of respiratory and critical care medicine 2005;171(8):899-907.
2005: Everhart M Brett; Han Wei; Parman Kelly S; Polosukhin Vasiliy V; Zeng Heng; Sadikot Ruxana T; Li Bo; Yull Fiona E; Christman John W; Blackwell Timothy S
Intratracheal administration of liposomal clodronate accelerates alveolar macrophage reconstitution following fetal liver transplantation.
Journal of leukocyte biology 2005;77(2):173-80.
2005: Maus Ulrich A; Wellmann Sandra; Hampl Christine; Kuziel William A; Srivastava Mrigank; Mack Matthias; Everhart M Brett; Blackwell Timothy S; Christman John W; Schlöndorff Detlef; Bohle Rainer M; Seeger Werner; Lohmeyer Jürgen
CCR2-positive monocytes recruited to inflamed lungs downregulate local CCL2 chemokine levels.
American journal of physiology. Lung cellular and molecular physiology 2005;288(2):L350-8.
2005: Polosukhin Vasiliy V; Stathopoulos Georgios T; Lawson William E; Blackwell Timothy S
Variability of interalveolar septal remodeling after bleomycin treatment in mice.
Ultrastructural pathology 2005;29(1):53-64.
2005: Sadikot Ruxana T; Blackwell Timothy S
Bioluminescence imaging.
Proceedings of the American Thoracic Society 2005;2(6):537-40, 511-2.
2004: Lawson W E; Grant S W; Ambrosini V; Womble K E; Dawson E P; Lane K B; Markin C; Renzoni E; Lympany P; Thomas A Q; Roldan J; Scott T A; Blackwell T S; Phillips J A; Loyd J E; du Bois R M
Genetic mutations in surfactant protein C are a rare cause of sporadic cases of IPF.
Thorax 2004;59(11):977-80.
2004: Sadikot R T; Christman J W; Blackwell T S
Molecular targets for modulating lung inflammation and injury.
Current drug targets 2004;5(6):581-8.
2004: Maus Ulrich A; Srivastava Mrigank; Paton James C; Mack Matthias; Everhart M Brett; Blackwell Timothy S; Christman John W; Schlöndorff Detlef; Seeger Werner; Lohmeyer Jürgen
Pneumolysin-induced lung injury is independent of leukocyte trafficking into the alveolar space.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(2):1307-12.
2004: Park Gye Young; Joo Myungsoo; Pedchenko Tetyana; Blackwell Timothy S; Christman John W
Regulation of macrophage cyclooxygenase-2 gene expression by modifications of histone H3.
American journal of physiology. Lung cellular and molecular physiology 2004;286(5):L956-62.
2004: Joo Myungsoo; Park Gye Young; Wright Jeffrey G; Blackwell Timothy S; Atchison Michael L; Christman John W
Transcriptional regulation of the cyclooxygenase-2 gene in macrophages by PU.1.
The Journal of biological chemistry 2004;279(8):6658-65.
2004: Sadikot Ruxana T; Zeng Heng; Yull Fiona E; Li Bo; Cheng Dong-sheng; Kernodle Douglas S; Jansen E Duco; Contag Christopher H; Segal Brahm H; Holland Steven M; Blackwell Timothy S; Christman John W
p47phox deficiency impairs NF-kappa B activation and host defense in Pseudomonas pneumonia.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(3):1801-8.
2003: Kalomenidis Ioannis; Lane Kirk; Blackwell Timothy S; Guo Yubiao; Light Richard W
Mice are resistant to the induction of a pleurodesis.
Chest 2003;124(6):2407-8.
2003: Gray Keith D; Simovic Misho O; Chapman William C; Blackwell Timothy S; Christman John W; May Addison K; Parman Kelly S; Stain Steven C
Endotoxin potentiates lung injury in cerulein-induced pancreatitis.
American journal of surgery 2003;186(5):526-30.
2003: Lee Y C G; Lane K B; Zoia O; Thompson P J; Light R W; Blackwell T S
Transforming growth factor-beta induces collagen synthesis without inducing IL-8 production in mesothelial cells.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2003;22(2):197-202.
2003: Yull Fiona E; Han Wei; Jansen E Duco; Everhart M Brett; Sadikot Ruxana T; Christman John W; Blackwell Timothy S
Bioluminescent detection of endotoxin effects on HIV-1 LTR-driven transcription in vivo.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2003;51(6):741-9.
2003: Gray Keith D; Simovic Misho O; Chapman William C; Blackwell Timothy S; Christman John W; Washington M Kay; Yull Fiona E; Jaffal Nada; Jansen E Duco; Gautman Shiva; Stain Steven C
Systemic nf-kappaB activation in a transgenic mouse model of acute pancreatitis.
The Journal of surgical research 2003;110(1):310-4.
2003: Maus Ulrich A; Waelsch Katharina; Kuziel William A; Delbeck Tim; Mack Matthias; Blackwell Timothy S; Christman John W; Schlöndorff Detlef; Seeger Werner; Lohmeyer Jürgen
Monocytes are potent facilitators of alveolar neutrophil emigration during lung inflammation: role of the CCL2-CCR2 axis.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(6):3273-8.
2003: Sadikot Ruxana T; Han Wei; Everhart M Brett; Zoia Ornella; Peebles R Stokes; Jansen E Duco; Yull Fiona E; Christman John W; Blackwell Timothy S
Selective I kappa B kinase expression in airway epithelium generates neutrophilic lung inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(2):1091-8.
2002: Koay M Audrey; Christman John W; Wudel L James; Allos Tara; Cheng Dong-Sheng; Chapman William C; Blackwell Timothy S
Modulation of endotoxin-induced NF-kappa B activation in lung and liver through TNF type 1 and IL-1 receptors.
American journal of physiology. Lung cellular and molecular physiology 2002;283(6):L1247-54.
2002: Maus Ulrich A; Koay M Audrey; Delbeck Tim; Mack Matthias; Ermert Monika; Ermert Leander; Blackwell Timothy S; Christman John W; Schlöndorff Detlef; Seeger Werner; Lohmeyer Jürgen
Role of resident alveolar macrophages in leukocyte traffic into the alveolar air space of intact mice.
American journal of physiology. Lung cellular and molecular physiology 2002;282(6):L1245-52.
2002: Koay M Audrey; Gao Xiang; Washington Mary Kay; Parman Kelly S; Sadikot Ruxana T; Blackwell Timothy S; Christman John W
Macrophages are necessary for maximal nuclear factor-kappa B activation in response to endotoxin.
American journal of respiratory cell and molecular biology 2002;26(5):572-8.
2002: Sadikot Ruxanna T; Wudel L James; Jansen Duco E; Debelak Jacob P; Yull Fiona E; Christman John W; Blackwell Timothy S; Chapman William C
Hepatic cryoablation-induced multisystem injury: bioluminescent detection of NF-kappaB activation in a transgenic mouse model.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2002;6(2):264-70.
2001: Koay M A; Christman J W; Segal B H; Venkatakrishnan A; Blackwell T R; Holland S M; Blackwell T S
Impaired pulmonary NF-kappaB activation in response to lipopolysaccharide in NADPH oxidase-deficient mice.
Infection and immunity 2001;69(10):5991-6.
2001: Sadikot R T; Jansen E D; Blackwell T R; Zoia O; Yull F; Christman J W; Blackwell T S
High-dose dexamethasone accentuates nuclear factor-kappa b activation in endotoxin-treated mice.
American journal of respiratory and critical care medicine 2001;164(5):873-8.
2001: Blackwell T S; Stecenko A A; Christman J W
Dysregulated NF-kappaB activation in cystic fibrosis: evidence for a primary inflammatory disorder.
American journal of physiology. Lung cellular and molecular physiology 2001;281(1):L69-70.
2001: Stecenko A A; King G; Torii K; Breyer R M; Dworski R; Blackwell T S; Christman J W; Brigham K L
Dysregulated cytokine production in human cystic fibrosis bronchial epithelial cells.
Inflammation 2001;25(3):145-55.
2001: Lancaster L H; Christman J W; Blackwell T R; Koay M A; Blackwell T S
Suppression of lung inflammation in rats by prevention of NF-kappaB activation in the liver.
Inflammation 2001;25(1):25-31.
2000: Sadikot R T; Christman J W; Blackwell T S
Chemokines and chemokine receptors in pulmonary diseases.
Current opinion in investigational drugs (London, England : 2000) 2000;1(3):314-20.
2000: Blackwell T S; Yull F E; Chen C L; Venkatakrishnan A; Blackwell T R; Hicks D J; Lancaster L H; Christman J W; Kerr L D
Multiorgan nuclear factor kappa B activation in a transgenic mouse model of systemic inflammation.
American journal of respiratory and critical care medicine 2000;162(3 Pt 1):1095-101.
2000: Venkatakrishnan A; Stecenko A A; King G; Blackwell T R; Brigham K L; Christman J W; Blackwell T S
Exaggerated activation of nuclear factor-kappaB and altered IkappaB-beta processing in cystic fibrosis bronchial epithelial cells.
American journal of respiratory cell and molecular biology 2000;23(3):396-403.
2000: Chapman W C; Debelak J P; Blackwell T S; Gainer K A; Christman J W; Pinson C W; Brigham K L; Parker R E
Hepatic cryoablation-induced acute lung injury: pulmonary hemodynamic and permeability effects in a sheep model.
Archives of surgery (Chicago, Ill. : 1960) 2000;135(6):667-72; discussion 672-3.
2000: Christman J W; Sadikot R T; Blackwell T S
The role of nuclear factor-kappa B in pulmonary diseases.
Chest 2000;117(5):1482-7.
2000: Chapman W C; Debelak J P; Wright Pinson C; Washington M K; Atkinson J B; Venkatakrishnan A; Blackwell T S; Christman J W
Hepatic cryoablation, but not radiofrequency ablation, results in lung inflammation.
Annals of surgery 2000;231(5):752-61.
2000: Blackwell T S; Christman J W; Hagan T; Price P; Edens T; Morris P E; Wolff S N; Goodman S A; Christman B W
Oxidative stress and NF-kappaB activation: correlation in patients following allogeneic bone marrow transplantation.
Antioxidants & redox signaling 2000;2(1):93-102.
1999: Blackwell T S; Lancaster L H; Blackwell T R; Venkatakrishnan A; Christman J W
Differential NF-kappaB activation after intratracheal endotoxin.
The American journal of physiology 1999;277(4 Pt 1):L823-30.
1999: Blackwell T S; Debelak J P; Venkatakrishnan A; Schot D J; Harley D H; Pinson C W; Williams P; Washington K; Christman J W; Chapman W C
Acute lung injury after hepatic cryoablation: correlation with NF-kappa B activation and cytokine production.
Surgery 1999;126(3):518-26.
1999: Blackwell T S; Yull F E; Chen C L; Venkatakrishnan A; Blackwell T R; Hicks D J; Lancaster L H; Christman J W; Kerr L D
Use of genetically altered mice to investigate the role of nuclear factor-kappa B activation and cytokine gene expression in sepsis-induced ARDS.
Chest 1999;116(1 Suppl):73S-74S.
1999: Blackwell T S; Lancaster L H; Blackwell T R; Venkatakrishnan A; Christman J W
Chemotactic gradients predict neutrophilic alveolitis in endotoxin-treated rats.
American journal of respiratory and critical care medicine 1999;159(5 Pt 1):1644-52.
1998: Christman J W; Lancaster L H; Blackwell T S
Nuclear factor kappa B: a pivotal role in the systemic inflammatory response syndrome and new target for therapy.
Intensive care medicine 1998;24(11):1131-8.
1997: Blackwell T S; Blackwell T R; Christman J W
Induction of endotoxin tolerance depletes nuclear factor-kappaB and suppresses its activation in rat alveolar macrophages.
Journal of leukocyte biology 1997;62(6):885-91.
1997: Blackwell T S; Blackwell T R; Christman J W
Impaired activation of nuclear factor-kappaB in endotoxin-tolerant rats is associated with down-regulation of chemokine gene expression and inhibition of neutrophilic lung inflammation.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(12):5934-40.
1996: Blackwell T S; Blackwell T R; Holden E P; Christman B W; Christman J W
In vivo antioxidant treatment suppresses nuclear factor-kappa B activation and neutrophilic lung inflammation.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(4):1630-7.
1996: Blackwell T S; Christman J W
Sepsis and cytokines: current status.
British journal of anaesthesia 1996;77(1):110-7.
1995: Christman J W; Holden E P; Blackwell T S
Strategies for blocking the systemic effects of cytokines in the sepsis syndrome.
Critical care medicine 1995;23(5):955-63.
1994: Blackwell T S; Holden E P; Blackwell T R; DeLarco J E; Christman J W
Cytokine-induced neutrophil chemoattractant mediates neutrophilic alveolitis in rats: association with nuclear factor kappa B activation.
American journal of respiratory cell and molecular biology 1994;11(4):464-72.

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