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Wolf-Dieter Schleuning

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Philip Daniel; Wolfram Lux; Andre L Samson; Wolf-Dieter Schleuning; Be'eri Niego; Thomas Weiss; Anna Tjärnlund-Wolf; Robert L Medcalf
Two conserved regions within the tissue-type plasminogen activator gene promoter mediate regulation by brain-derived neurotrophic factor.
Mandana Rad; Michael Hümpel; Olaf Schaefer; Rik C Schoemaker; Wolf-Dieter Schleuning; Adam Cohen; Jacobus Burggraaf
Pharmacokinetics and systemic endocrine effects of the phyto-oestrogen 8-prenylnaringenin after single oral doses to postmenopausal women.
Michael Hümpel; Päivi Isaksson; Olaf Schaefer; Ulrike Kaufmann; Paolo Ciana; Stefano Di Giovine; Wolf-Dieter Schleuning
Tissue specificity of 8-prenylnaringenin: protection from ovariectomy induced bone loss with minimal trophic effects on the uterus.

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2007: Philip Daniel; Wolfram Lux; Andre L Samson; Wolf-Dieter Schleuning; Be'eri Niego; Thomas Weiss; Anna Tjärnlund-Wolf; Robert L Medcalf
Two conserved regions within the tissue-type plasminogen activator gene promoter mediate regulation by brain-derived neurotrophic factor.
The FEBS journal 2007;274(9):2411-23.
2006: Mandana Rad; Michael Hümpel; Olaf Schaefer; Rik C Schoemaker; Wolf-Dieter Schleuning; Adam Cohen; Jacobus Burggraaf
Pharmacokinetics and systemic endocrine effects of the phyto-oestrogen 8-prenylnaringenin after single oral doses to postmenopausal women.
British journal of clinical pharmacology 2006;62(3):288-96.
2005: Michael Hümpel; Päivi Isaksson; Olaf Schaefer; Ulrike Kaufmann; Paolo Ciana; Stefano Di Giovine; Wolf-Dieter Schleuning
Tissue specificity of 8-prenylnaringenin: protection from ovariectomy induced bone loss with minimal trophic effects on the uterus.
The Journal of steroid biochemistry and molecular biology 2005;97(3):299-305.
2005: Courtney Reddrop; Randal X Moldrich; Philip M Beart; Mark C Farso; Gabriel T Liberatore; David W Howells; Karl-Uwe Petersen; Wolf-Dieter Schleuning; Robert L Medcalf
Vampire bat salivary plasminogen activator (desmoteplase) inhibits tissue-type plasminogen activator-induced potentiation of excitotoxic injury.
Stroke; a journal of cerebral circulation 2005;36(6):1241-6.
2005: W Lux; H-G Klobeck; Philip Daniel; M Costa; Robert L Medcalf; Wolf-Dieter Schleuning
In vivo and in vitro analysis of the human tissue-type plasminogen activator gene promoter in neuroblastomal cell lines: evidence for a functional upstream kappaB element.
Journal of thrombosis and haemostasis : JTH 2005;3(5):1009-17.
2005: Olaf Schaefer; Rolf Bohlmann; Wolf-Dieter Schleuning; Kai Schulze-Forster; Michael Hümpel
Development of a radioimmunoassay for the quantitative determination of 8-prenylnaringenin in biological matrices.
Journal of agricultural and food chemistry 2005;53(8):2881-9.
2004: Egbert Kruithof; Wolf-Dieter Schleuning
A comparative study of amyloid-beta (1-42) as a cofactor for plasminogen activation by vampire bat plasminogen activator and recombinant human tissue-type plasminogen activator.
Thrombosis and haemostasis 2004;92(3):559-67.
2004: Guido Epple; Wolf-Dieter Schleuning; Gerhard Kettelgerdes; Eckart Kottgen; Reinhard Gessner; Michael Praus
Prion protein stimulates tissue-type plasminogen activator-mediated plasmin generation via a lysine-binding site on kringle 2.
Journal of thrombosis and haemostasis : JTH 2004;2(6):962-8.
2004: Michael S Pepper; Susan J Hazel; Michael Hümpel; Wolf-Dieter Schleuning
8-prenylnaringenin, a novel phytoestrogen, inhibits angiogenesis in vitro and in vivo.
Journal of cellular physiology 2004;199(1):98-107.
2004: Guido Epple; Kristina Langfeld; Michael Baier; Hermann-Georg Holzhütter; Wolf-Dieter Schleuning; Eckart Köttgen; Reinhard Gessner; Michael Praus
Both lysine-clusters of the NH2-terminal prion-protein fragment PrP23-110 are essential for t-PA mediated plasminogen activation.
Thrombosis and haemostasis 2004;91(3):465-72.
2003: Michael Praus; Gerhard Kettelgerdes; Michael Baier; Hermann-Georg Holzhütter; Peter Jungblut; Manuela Maissen; Guido Epple; Wolf-Dieter Schleuning; Eckart Köttgen; Adriano Aguzzi; Reinhard Gessner
Stimulation of plasminogen activation by recombinant cellular prion protein is conserved in the NH2-terminal fragment PrP23-110.
Thrombosis and haemostasis 2003;89(5):812-9.
2003: Olaf Schaefer; Michael Hümpel; Karl-Heinrich Fritzemeier; Rolf Bohlmann; Wolf-Dieter Schleuning
8-Prenyl naringenin is a potent ERalpha selective phytoestrogen present in hops and beer.
The Journal of steroid biochemistry and molecular biology 2003;84(2-3):359-60.
2003: Gabriel T Liberatore; Andre L Samson; Christopher Bladin; Wolf-Dieter Schleuning; Robert L Medcalf
Vampire bat salivary plasminogen activator (desmoteplase): a unique fibrinolytic enzyme that does not promote neurodegeneration.
Stroke; a journal of cerebral circulation 2003;34(2):537-43.
2002: Christoph Geserick; Bertram Weiss; Wolf-Dieter Schleuning; Bernard Haendler
OTEX, an androgen-regulated human member of the paired-like class of homeobox genes.
The Biochemical journal 2002;366(Pt 1):367-75.
2001: K Barbulescu; Christoph Geserick; I Schüttke; Wolf-Dieter Schleuning; Bernard Haendler
New androgen response elements in the murine pem promoter mediate selective transactivation.
Molecular endocrinology (Baltimore, Md.) 2001;15(10):1803-16.
2001: H Yu; Wolf-Dieter Schleuning; M Michl; Gabriel T Liberatore; S S Tan; Robert L Medcalf
Control elements between -9.5 and -3.0 kb in the human tissue-type plasminogen activator gene promoter direct spatial and inducible expression to the murine brain.
The European journal of neuroscience 2001;14(5):799-808.
2001: Bernard Haendler; I Schüttke; Wolf-Dieter Schleuning
Androgen receptor signalling: comparative analysis of androgen response elements and implication of heat-shock protein 90 and 14-3-3eta.
Molecular and cellular endocrinology 2001;173(1-2):63-73.
1999: Bernard Haendler; I Toda; david sullivan; Wolf-Dieter Schleuning
Expression of transcripts for cysteine-rich secretory proteins (CRISPs) in the murine lacrimal gland.
Journal of cellular physiology 1999;178(3):371-8.
1998: M Konakova; F Hucho; Wolf-Dieter Schleuning
Downstream targets of urokinase-type plasminogen-activator-mediated signal transduction.
European journal of biochemistry / FEBS 1998;253(2):421-9.
1997: Bernard Haendler; U F Habenicht; U Schwidetzky; I Schüttke; Wolf-Dieter Schleuning
Differential androgen regulation of the murine genes for cysteine-rich secretory proteins (CRISP).
European journal of biochemistry / FEBS 1997;250(2):440-6.
1997: M Kapelle; J Krätzschmar; M Husemann; Wolf-Dieter Schleuning
cDNA cloning of two closely related forms of human germ cell nuclear factor (GCNF).
Biochimica et biophysica acta 1997;1352(1):13-7.
1997: U Schwidetzky; Wolf-Dieter Schleuning; Bernard Haendler
Isolation and characterization of the androgen-dependent mouse cysteine-rich secretory protein-1 (CRISP-1) gene.
The Biochemical journal 1997;321 ( Pt 2)():325-32.
1996: P Pfisterer; H König; J Hess; G Lipowsky; Bernard Haendler; Wolf-Dieter Schleuning; Thomas Wirth
CRISP-3, a protein with homology to plant defense proteins, is expressed in mouse B cells under the control of Oct2.
Molecular and cellular biology 1996;16(11):6160-8.
1996: J Krätzschmar; Bernard Haendler; U Eberspaecher; D Roosterman; Peter Donner; Wolf-Dieter Schleuning
The human cysteine-rich secretory protein (CRISP) family. Primary structure and tissue distribution of CRISP-1, CRISP-2 and CRISP-3.
European journal of biochemistry / FEBS 1996;236(3):827-36.
1996: Bernard Haendler; A Becker; C Noeske-Jungblut; J Krätzschmar; Peter Donner; Wolf-Dieter Schleuning
Expression, purification and characterisation of recombinant pallidipin, a novel platelet aggregation inhibitor from the haematophageous triatomine bug Triatoma pallidipennis.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 1996;7(2):183-6.
1995: C Noeske-Jungblut; Bernard Haendler; Peter Donner; A Alagon; L Possani; Wolf-Dieter Schleuning
Triabin, a highly potent exosite inhibitor of thrombin.
The Journal of biological chemistry 1995;270(48):28629-34.
1995: P Bringmann; D Gruber; A Liese; L Toschi; J Krätzchmar; Wolf-Dieter Schleuning; Peter Donner
Structural features mediating fibrin selectivity of vampire bat plasminogen activators.
The Journal of biological chemistry 1995;270(43):25596-603.
1995: U Eberspaecher; D Roosterman; J Krätzschmar; Bernard Haendler; U F Habenicht; A Becker; C Quensel; Thomas Petri; Wolf-Dieter Schleuning; Peter Donner
Mouse androgen-dependent epididymal glycoprotein CRISP-1 (DE/AEG): isolation, biochemical characterization, and expression in recombinant form.
Molecular reproduction and development 1995;42(2):157-72.
1995: G Langer; L Toschi; J Dieckmann; Wolf-Dieter Schleuning
Low-M(r) urokinase-type plasminogen activator as a reporter protein.
Gene 1995;161(2):287-92.
1995: U Schwidetzky; Bernard Haendler; Wolf-Dieter Schleuning
Isolation and characterization of the androgen-dependent mouse cysteine-rich secretory protein-3 (CRISP-3) gene.
The Biochemical journal 1995;309 ( Pt 3)():831-6.
1995: Peter Donner; C Noeske-Jungblut; Wolf-Dieter Schleuning
[New thrombolytic and anticoagulant drugs from the saliva of blood-sucking animals].
Pharmazie in unserer Zeit 1995;24(3):125-9.
1995: Bernard Haendler; A Becker; C Noeske-Jungblut; J Krätzschmar; Peter Donner; Wolf-Dieter Schleuning
Expression of active recombinant pallidipin, a novel platelet aggregation inhibitor, in the periplasm of Escherichia coli.
The Biochemical journal 1995;307 ( Pt 2)():465-70.
1995: Thomas Petri; G Langer; P Bringmann; L Cashion; S Shallow; Wolf-Dieter Schleuning; Peter Donner
Production of vampire bat plasminogen activator DSPA alpha 1 in CHO and insect cells.
Journal of biotechnology 1995;39(1):75-83.
1995: A Schmid; K H Thierauch; Wolf-Dieter Schleuning; Harald Dinter
Splice variants of the human EP3 receptor for prostaglandin E2.
European journal of biochemistry / FEBS 1995;228(1):23-30.
1994: X Zheng; Margarethe Geiger; S Ecke; Edith Bielek; Peter Donner; U Eberspächer; Wolf-Dieter Schleuning; Bernd R Binder
Inhibition of acrosin by protein C inhibitor and localization of protein C inhibitor to spermatozoa.
The American journal of physiology 1994;267(2 Pt 1):C466-72.
1994: W Witt; B Maass; B Baldus; M Hildebrand; Peter Donner; Wolf-Dieter Schleuning
Coronary thrombolysis with Desmodus salivary plasminogen activator in dogs. Fast and persistent recanalization by intravenous bolus administration.
Circulation 1994;90(1):421-6.
1994: A Becker; Bernard Haendler; U Hechler; Wolf-Dieter Schleuning
Mutational analysis of human endothelin receptors ETA and ETB identification of regions involved in the selectivity for endothelin 3 or cyclo-(D-Trp-D-Asp-Pro-D-Val-Leu).
European journal of biochemistry / FEBS 1994;221(3):951-8.
1994: I Dumler; Thomas Petri; Wolf-Dieter Schleuning
Induction of c-fos gene expression by urokinase-type plasminogen activator in human ovarian cancer cells.
FEBS letters 1994;343(2):103-6.
1994: C Noeske-Jungblut; J Krätzschmar; Bernard Haendler; A Alagon; L Possani; P Verhallen; Peter Donner; Wolf-Dieter Schleuning
An inhibitor of collagen-induced platelet aggregation from the saliva of Triatoma pallidipennis.
The Journal of biological chemistry 1994;269(7):5050-3.
1994: A Becker; F Theuring; M Gottwald; K Kauser; Wolf-Dieter Schleuning; Peter Donner
Purification of human big endothelin 1 derived through cleavage with collagenase and dipeptidylpeptidase IV from a fusion protein expressed in Escherichia coli.
Protein expression and purification 1994;5(1):50-6.
1993: U Hechler; A Becker; Bernard Haendler; Wolf-Dieter Schleuning
Stable expression of human endothelin receptors ETA and ETB by transfected baby hamster kidney cells.
Biochemical and biophysical research communications 1993;194(3):1305-10.
1993: Bernard Haendler; J Krätzschmar; F Theuring; Wolf-Dieter Schleuning
Transcripts for cysteine-rich secretory protein-1 (CRISP-1; DE/AEG) and the novel related CRISP-3 are expressed under androgen control in the mouse salivary gland.
Endocrinology 1993;133(1):192-8.
1993: I Dumler; Thomas Petri; Wolf-Dieter Schleuning
Interaction of urokinase-type plasminogenactivator (u-PA) with its cellular receptor (u-PAR) induces phosphorylation on tyrosine of a 38 kDa protein.
FEBS letters 1993;322(1):37-40.
1993: J Krätzschmar; Bernard Haendler; S Kojima; D B Rifkin; Wolf-Dieter Schleuning
Bovine urokinase-type plasminogen activator and its receptor: cloning and induction by retinoic acid.
Gene 1993;125(2):177-83.
1993: Bernard Haendler; U Hechler; A Becker; Wolf-Dieter Schleuning
Expression of human endothelin receptor ETB by Escherichia coli transformants.
Biochemical and biophysical research communications 1993;191(2):633-8.
1993: A Becker; E B Dowdle; U Hechler; K Kauser; Peter Donner; Wolf-Dieter Schleuning
Bibrotoxin, a novel member of the endothelin/sarafotoxin peptide family, from the venom of the burrowing asp Atractaspis bibroni.
FEBS letters 1993;315(1):100-3.
1993: Bernard Haendler; U Hechler; A Becker; Wolf-Dieter Schleuning
Extracellular cysteine residues 174 and 255 are essential for active expression of human endothelin receptor ETB in Escherichia coli.
Journal of cardiovascular pharmacology 1993;22 Suppl 8():S4-6.
1993: U Hechler; A Becker; Bernard Haendler; Wolf-Dieter Schleuning
Binding characteristics of recombinant human endothelin receptors ETA and ETB expressed in baby hamster kidney cells.
Journal of cardiovascular pharmacology 1993;22 Suppl 8():S15-7.
1992: Wolf-Dieter Schleuning; A Alagon; W Boidol; P Bringmann; Thomas Petri; J Krätzschmar; Bernard Haendler; G Langer; B Baldus; W Witt
Plasminogen activators from the saliva of Desmodus rotundus (common vampire bat): unique fibrin specificity.
Annals of the New York Academy of Sciences 1992;667():395-403.
1992: J Krätzschmar; Bernard Haendler; P Bringmann; Harald Dinter; H Hess; Peter Donner; Wolf-Dieter Schleuning
High-level secretion of the four salivary plasminogen activators from the vampire bat Desmodus rotundus by stably transfected baby hamster kidney cells.
Gene 1992;116(2):281-4.
1992: W Witt; B Baldus; P Bringmann; L Cashion; Peter Donner; Wolf-Dieter Schleuning
Thrombolytic properties of Desmodus rotundus (vampire bat) salivary plasminogen activator in experimental pulmonary embolism in rats.
Blood 1992;79(5):1213-7.
1992: M Ludwig; K D Wohn; Wolf-Dieter Schleuning; K Olek
Allelic dimorphism in the human tissue-type plasminogen activator (TPA) gene as a result of an Alu insertion/deletion event.
Human genetics 1992;88(4):388-92.
1992: Bernard Haendler; U Hechler; Wolf-Dieter Schleuning
Molecular cloning of human endothelin (ET) receptors ETA and ETB.
Journal of cardiovascular pharmacology 1992;20 Suppl 12():S1-4.
1991: U Eberspaecher; J Gerwien; U F Habenicht; Wolf-Dieter Schleuning; Peter Donner
Activation and subsequent degradation of proacrosin is mediated by zona pellucida glycoproteins, negatively charged polysaccharides, and DNA.
Molecular reproduction and development 1991;30(2):164-70.
1991: J Krätzschmar; Bernard Haendler; G Langer; W Boidol; P Bringmann; A Alagon; Peter Donner; Wolf-Dieter Schleuning
The plasminogen activator family from the salivary gland of the vampire bat Desmodus rotundus: cloning and expression.
Gene 1991;105(2):229-37.
1991: M Ludwig; K D Wohn; G Langer; Wolf-Dieter Schleuning; K Olek
Detection of a TaqI polymorphism within the human TPA gene (PLAT).
Nucleic acids research 1991;19(16):4575.
1990: K D Wohn; M Ludwig; G Langer; K Olek; Wolf-Dieter Schleuning
XmnI polymorphism in the human TPA gene.
Nucleic acids research 1990;18(17):5326.
1990: Niels Behrendt; E Rønne; Michael Ploug; Thomas Petri; D Løber; L S Nielsen; Wolf-Dieter Schleuning; F Blasi; E Appella; Keld Danø
The human receptor for urokinase plasminogen activator. NH2-terminal amino acid sequence and glycosylation variants.
The Journal of biological chemistry 1990;265(11):6453-60.