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Donald Schmechel

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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TOP 3
Züchner S; Gilbert J R; Martin E R; Leon-Guerrero C R; Xu P-T; Browning C; Bronson P G; Whitehead P; Schmechel D E; Haines J L; Pericak-Vance M A
Linkage and association study of late-onset Alzheimer disease families linked to 9p21.3.
Sullivan Patrick M; Mace Brian E; Estrada Januario C; Schmechel Donald E; Alberts Mark J
Human apolipoprotein E4 targeted replacement mice show increased prevalence of intracerebral hemorrhage associated with vascular amyloid deposition.
Carney R M; Slifer M A; Lin P I; Gaskell P C; Scott W K; Potocky C F; Hulette C M; Welsh-Bohmer K A; Schmechel D E; Vance J M; Pericak-Vance M A
Longitudinal follow-up of late-onset Alzheimer disease families.

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All Publications

2008: Züchner S; Gilbert J R; Martin E R; Leon-Guerrero C R; Xu P-T; Browning C; Bronson P G; Whitehead P; Schmechel D E; Haines J L; Pericak-Vance M A
Linkage and association study of late-onset Alzheimer disease families linked to 9p21.3.
Annals of human genetics 2008;72(Pt 6):725-31.
2008: Sullivan Patrick M; Mace Brian E; Estrada Januario C; Schmechel Donald E; Alberts Mark J
Human apolipoprotein E4 targeted replacement mice show increased prevalence of intracerebral hemorrhage associated with vascular amyloid deposition.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2008;17(5):303-11.
2008: Carney R M; Slifer M A; Lin P I; Gaskell P C; Scott W K; Potocky C F; Hulette C M; Welsh-Bohmer K A; Schmechel D E; Vance J M; Pericak-Vance M A
Longitudinal follow-up of late-onset Alzheimer disease families.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2008;147B(5):571-8.
2008: Browndyke Jeffrey N; Paskavitz James; Sweet Lawrence H; Cohen Ronald A; Tucker Karen A; Welsh-Bohmer Kathleen A; Burke James R; Schmechel Donald E
Neuroanatomical correlates of malingered memory impairment: event-related fMRI of deception on a recognition memory task.
Brain injury : [BI] 2008;22(6):481-9.
2008: Liang Winnie S; Dunckley Travis; Beach Thomas G; Grover Andrew; Mastroeni Diego; Ramsey Keri; Caselli Richard J; Kukull Walter A; McKeel Daniel; Morris John C; Hulette Christine M; Schmechel Donald; Reiman Eric M; Rogers Joseph; Stephan Dietrich A
Altered neuronal gene expression in brain regions differentially affected by Alzheimer's disease: a reference data set.
Physiological genomics 2008;33(2):240-56.
2008: Liang Winnie S; Reiman Eric M; Valla Jon; Dunckley Travis; Beach Thomas G; Grover Andrew; Niedzielko Tracey L; Schneider Lonnie E; Mastroeni Diego; Caselli Richard; Kukull Walter; Morris John C; Hulette Christine M; Schmechel Donald; Rogers Joseph; Stephan Dietrich A
Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(11):4441-6.
2008: Liang Xueying; Schnetz-Boutaud Nathalie; Bartlett Jackie; Allen Melissa J; Gwirtsman Harry; Schmechel Don E; Carney Regina M; Gilbert John R; Pericak-Vance Margaret A; Haines Jonathan L
No association between SNP rs498055 on chromosome 10 and late-onset Alzheimer disease in multiple datasets.
Annals of human genetics 2008;72(Pt 1):141-4.
2007: Xu Pu-Ting; Li Yi-Ju; Qin Xue-Jun; Kroner Charles; Green-Odlum Anya; Xu Hong; Wang Tian-Yuan; Schmechel Donald E; Hulette Christine M; Ervin John; Hauser Mike; Haines Jonathan; Pericak-Vance Margaret A; Gilbert John R
A SAGE study of apolipoprotein E3/3, E3/4 and E4/4 allele-specific gene expression in hippocampus in Alzheimer disease.
Molecular and cellular neurosciences 2007;36(3):313-31.
2007: Liang Xueying; Martin Eden R; Schnetz-Boutaud Nathalie; Bartlett Jackie; Anderson Brent; Züchner Stephan; Gwirtsman Harry; Schmechel Don; Carney Regina; Gilbert John R; Pericak-Vance Margaret A; Haines Jonathan L
Effect of heterogeneity on the chromosome 10 risk in late-onset Alzheimer disease.
Human mutation 2007;28(11):1065-73.
2007: Schmechel Donald Everett
Art, alpha-1-antitrypsin polymorphisms and intense creative energy: blessing or curse?
Neurotoxicology 2007;28(5):899-914.
2007: Sugarman Jeremy; Roter Debra; Cain Carole; Wallace Roberta; Schmechel Don; Welsh-Bohmer Kathleen A
Proxies and consent discussions for dementia research.
Journal of the American Geriatrics Society 2007;55(4):556-61.
2007: Liang Winnie S; Dunckley Travis; Beach Thomas G; Grover Andrew; Mastroeni Diego; Walker Douglas G; Caselli Richard J; Kukull Walter A; McKeel Daniel; Morris John C; Hulette Christine; Schmechel Donald; Alexander Gene E; Reiman Eric M; Rogers Joseph; Stephan Dietrich A
Gene expression profiles in anatomically and functionally distinct regions of the normal aged human brain.
Physiological genomics 2007;28(3):311-22.
2007: Liang Xueying; Schnetz-Boutaud Nathalie; Bartlett Jackie; Anderson Brent M; Gwirtsman Harry; Schmechel Don; Carney Regina; Gilbert John R; Pericak-Vance Margaret A; Haines Jonathan L
Association analysis of genetic polymorphisms in the CDC2 gene with late-onset Alzheimer disease.
Dementia and geriatric cognitive disorders 2007;23(2):126-32.
2006: Dunckley Travis; Beach Thomas G; Ramsey Keri E; Grover Andrew; Mastroeni Diego; Walker Douglas G; LaFleur Bonnie J; Coon Keith D; Brown Kevin M; Caselli Richard; Kukull Walter; Higdon Roger; McKeel Daniel; Morris John C; Hulette Christine; Schmechel Donald; Reiman Eric M; Rogers Joseph; Stephan Dietrich A
Gene expression correlates of neurofibrillary tangles in Alzheimer's disease.
Neurobiology of aging 2006;27(10):1359-71.
2006: Schmechel Donald E; Browndyke Jeffrey; Ghio Andrew
Strategies for dissecting genetic-environmental interactions in neurodegenerative disorders.
Neurotoxicology 2006;27(5):637-57.
2006: Lin P I; Martin E R; Bronson P G; Browning-Large C; Small G W; Schmechel D E; Welsh-Bohmer K A; Haines J L; Gilbert J R; Pericak-Vance M A
Exploring the association of glyceraldehyde-3-phosphate dehydrogenase gene and Alzheimer disease.
Neurology 2006;67(1):64-8.
2006: Lin Ping-I; Martin Eden R; Browning-Large Carrie A; Schmechel Donald E; Welsh-Bohmer Kathleen A; Doraiswamy P Murali; Gilbert John R; Haines Jonathan L; Pericak-Vance Margaret A
Parsing the genetic heterogeneity of chromosome 12q susceptibility genes for Alzheimer disease by family-based association analysis.
Neurogenetics 2006;7(3):157-65.
2006: Xu Pu-Ting; Li Yi-Ju; Qin Xue-Jun; Scherzer Clemens R; Xu Hong; Schmechel Donald E; Hulette Christine M; Ervin John; Gullans Steven R; Haines Jonathan; Pericak-Vance Margaret A; Gilbert John R
Differences in apolipoprotein E3/3 and E4/4 allele-specific gene expression in hippocampus in Alzheimer disease.
Neurobiology of disease 2006;21(2):256-75.
2006: Malek Goldis; Mace Brian; Saloupis Peter; Schmechel Donald; Rickman Dennis; Sullivan Patrick; Rickman Catherine Bowes
Initial observations of key features of age-related macular degeneration in APOE targeted replacement mice.
Advances in experimental medicine and biology 2006;572():109-17.
2006: Li Yi-Ju; Xu Puting; Qin Xuejun; Schmechel Donald E; Hulette Christine M; Haines Jonathan L; Pericak-Vance Margaret A; Gilbert John R
A comparative analysis of the information content in long and short SAGE libraries.
BMC bioinformatics 2006;7():504.
2005: Martin E R; Bronson P G; Li Y-J; Wall N; Chung R-H; Schmechel D E; Small G; Xu P-T; Bartlett J; Schnetz-Boutaud N; Haines J L; Gilbert J R; Pericak-Vance M A
Interaction between the alpha-T catenin gene (VR22) and APOE in Alzheimer's disease.
Journal of medical genetics 2005;42(10):787-92.
2005: Noureddine Maher A; Li Yi-Ju; van der Walt Joelle M; Walters Robert; Jewett Rita M; Xu Hong; Wang Tianyuan; Walter Jeffrey W; Scott Burton L; Hulette Christine; Schmechel Don; Stenger Judith E; Dietrich Fred; Vance Jeffery M; Hauser Michael A
Genomic convergence to identify candidate genes for Parkinson disease: SAGE analysis of the substantia nigra.
Movement disorders : official journal of the Movement Disorder Society 2005;20(10):1299-309.
2005: Malek G; Johnson L V; Mace B E; Saloupis P; Schmechel D E; Rickman D W; Toth C A; Sullivan P M; Bowes Rickman C
Apolipoprotein E allele-dependent pathogenesis: a model for age-related retinal degeneration.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(33):11900-5.
2005: Corder Elizabeth H; Ervin John F; Lockhart Evelyn; Szymanski Mari H; Schmechel Donald E; Hulette Christine M
Cardiovascular damage in Alzheimer disease: autopsy findings from the Bryan ADRC.
Journal of biomedicine & biotechnology 2005;2005(2):189-97.
2005: Hauser Michael A; Li Yi-Ju; Xu Hong; Noureddine Maher A; Shao Yujun S; Gullans Steven R; Scherzer Clemens R; Jensen Roderick V; McLaurin Adam C; Gibson Jason R; Scott Burton L; Jewett Rita M; Stenger Judith E; Schmechel Donald E; Hulette Christine M; Vance Jeffery M
Expression profiling of substantia nigra in Parkinson disease, progressive supranuclear palsy, and frontotemporal dementia with parkinsonism.
Archives of neurology 2005;62(6):917-21.
2005: Mott Ryan T; Dickson Dennis W; Trojanowski John Q; Zhukareva Vicki; Lee Virginia M; Forman Mark; Van Deerlin Vivianna; Ervin John F; Wang Deng-Shun; Schmechel Donald E; Hulette Christine M
Neuropathologic, biochemical, and molecular characterization of the frontotemporal dementias.
Journal of neuropathology and experimental neurology 2005;64(5):420-8.
2005: Wang Chunsheng; Wilson Wilkie A; Moore Scott D; Mace Brian E; Maeda Nobuyo; Schmechel Donald E; Sullivan Patrick M
Human apoE4-targeted replacement mice display synaptic deficits in the absence of neuropathology.
Neurobiology of disease 2005;18(2):390-8.
2004: Nicodemus Kristin K; Stenger Judith E; Schmechel Donald E; Welsh-Bohmer Kathleen A; Saunders Ann M; Roses Allen D; Gilbert John R; Vance Jeffery M; Haines Jonathan L; Pericak-Vance Margaret A; Martin Eden R
Comprehensive association analysis of APOE regulatory region polymorphisms in Alzheimer disease.
Neurogenetics 2004;5(4):201-8.
2004: Ervin John F; Pannell Catherine; Szymanski Mari; Welsh-Bohmer Kathleen; Schmechel Donald E; Hulette Christine M
Vascular smooth muscle actin is reduced in Alzheimer disease brain: a quantitative analysis.
Journal of neuropathology and experimental neurology 2004;63(7):735-41.
2004: van der Walt Joelle M; Dementieva Yulia A; Martin Eden R; Scott William K; Nicodemus Kristin K; Kroner Charles C; Welsh-Bohmer Kathleen A; Saunders Ann M; Roses Allen D; Small Gary W; Schmechel Donald E; Murali Doraiswamy P; Gilbert John R; Haines Jonathan L; Vance Jeffery M; Pericak-Vance Margaret A
Analysis of European mitochondrial haplogroups with Alzheimer disease risk.
Neuroscience letters 2004;365(1):28-32.
2004: Colton Carol A; Needham Leila K; Brown Candice; Cook Danielle; Rasheed Karima; Burke James R; Strittmatter Warren J; Schmechel Donald E; Vitek Michael P
APOE genotype-specific differences in human and mouse macrophage nitric oxide production.
Journal of neuroimmunology 2004;147(1-2):62-7.
2004: Sullivan P M; Mace B E; Maeda N; Schmechel D E
Marked regional differences of brain human apolipoprotein E expression in targeted replacement mice.
Neuroscience 2004;124(4):725-33.
2003: Li Yi-Ju; Oliveira Sofia A; Xu Puting; Martin Eden R; Stenger Judith E; Scherzer Clemens R; Hauser Michael A; Scott William K; Small Gary W; Nance Martha A; Watts Ray L; Hubble Jean P; Koller William C; Pahwa Rajesh; Stern Mathew B; Hiner Bradley C; Jankovic Joseph; Goetz Christopher G; Mastaglia Frank; Middleton Lefkos T; Roses Allen D; Saunders Ann M; Schmechel Donald E; Gullans Steven R; Haines Jonathan L; Gilbert John R; Vance Jeffery M; Pericak-Vance Margaret A; Hulette Christine; Welsh-Bohmer Kathleen A
Glutathione S-transferase omega-1 modifies age-at-onset of Alzheimer disease and Parkinson disease.
Human molecular genetics 2003;12(24):3259-67.
2003: Scott William K; Hauser Elizabeth R; Schmechel Donald E; Welsh-Bohmer Kathleen A; Small Gary W; Roses Allen D; Saunders Ann M; Gilbert John R; Vance Jeffery M; Haines Jonathan L; Pericak-Vance Margaret A
Ordered-subsets linkage analysis detects novel Alzheimer disease loci on chromosomes 2q34 and 15q22.
American journal of human genetics 2003;73(5):1041-51.
2003: Kulasingam Shalini L; Samsa Gregory P; Zarin Deborah A; Rutschmann Olivier T; Patwardhan Meenal B; McCrory Douglas C; Schmechel Donald E; Matchar David B
When should functional neuroimaging techniques be used in the diagnosis and management of Alzheimer's dementia? A decision analysis.
Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 2003;6(5):542-50.
2003: Oliveira Sofia A; Martin Eden R; Scott William K; Nicodemus Kristin K; Small Gary W; Schmechel Donald E; Doraiswamy P Murali; Roses Allen D; Saunders Ann M; Gilbert John R; Haines Jonathan L; Vance Jeffery M; Pericak-Vance Margaret A
The Q7R Saitohin gene polymorphism is not associated with Alzheimer disease.
Neuroscience letters 2003;347(3):143-6.
2003: Trembath Yuri; Rosenberg Carolyn; Ervin John F; Schmechel Donald E; Gaskell Perry; Pericak-Vance Margaret; Vance Jeffery; Hulette Christine M
Lewy body pathology is a frequent co-pathology in familial Alzheimer's disease.
Acta neuropathologica 2003;105(5):484-8.
2003: van der Walt Joelle M; Nicodemus Kristin K; Martin Eden R; Scott William K; Nance Martha A; Watts Ray L; Hubble Jean P; Haines Jonathan L; Koller William C; Lyons Kelly; Pahwa Rajesh; Stern Matthew B; Colcher Amy; Hiner Bradley C; Jankovic Joseph; Ondo William G; Allen Fred H; Goetz Christopher G; Small Gary W; Mastaglia Frank; Stajich Jeffrey M; McLaurin Adam C; Middleton Lefkos T; Scott Burton L; Schmechel Donald E; Pericak-Vance Margaret A; Vance Jeffery M
Mitochondrial polymorphisms significantly reduce the risk of Parkinson disease.
American journal of human genetics 2003;72(4):804-11.
2003: Hauser Michael A; Li Yi-Ju; Takeuchi Satoshi; Walters Robert; Noureddine Maher; Maready Melinda; Darden Tiffany; Hulette Christine; Martin Eden; Hauser Elizabeth; Xu Hong; Schmechel Don; Stenger Judith E; Dietrich Fred; Vance Jeffery
Genomic convergence: identifying candidate genes for Parkinson's disease by combining serial analysis of gene expression and genetic linkage.
Human molecular genetics 2003;12(6):671-7.
2002: Colton Carol A; Brown Candice M; Cook Danielle; Needham Leila K; Xu Qing; Czapiga Meggan; Saunders Ann M; Schmechel Donald E; Rasheed Karima; Vitek Michael P
APOE and the regulation of microglial nitric oxide production: a link between genetic risk and oxidative stress.
Neurobiology of aging 2002;23(5):777-85.
2002: Li Yi-Ju; Scott William K; Hedges Dale J; Zhang Fengyu; Gaskell P Craig; Nance Martha A; Watts Ray L; Hubble Jean P; Koller William C; Pahwa Rajesh; Stern Matthew B; Hiner Bradley C; Jankovic Joseph; Allen Fred A; Goetz Christopher G; Mastaglia Frank; Stajich Jeffrey M; Gibson Rachel A; Middleton Lefkos T; Saunders Ann M; Scott Burton L; Small Gary W; Nicodemus Kristin K; Reed Allison D; Schmechel Donald E; Welsh-Bohmer Kathleen A; Conneally P Michael; Roses Allen D; Gilbert John R; Vance Jeffery M; Haines Jonathan L; Pericak-Vance Margaret A
Age at onset in two common neurodegenerative diseases is genetically controlled.
American journal of human genetics 2002;70(4):985-93.
2001: Schmechel D E; Koltai D C
Potential human health effects associated with laboratory exposures to Pfiesteria piscicida.
Environmental health perspectives 2001;109 Suppl 5():775-9.
2001: Clayton C E; Carraway M S; Suliman H B; Thalmann E D; Thalmann K N; Schmechel D E; Piantadosi C A
Inhaled carbon monoxide and hyperoxic lung injury in rats.
American journal of physiology. Lung cellular and molecular physiology 2001;281(4):L949-57.
2000: Harry G J; Lefebvre d'Hellencourt C; Bruccoleri A; Schmechel D
Age-dependent cytokine responses: trimethyltin hippocampal injury in wild-type, APOE knockout, and APOE4 mice.
Brain, behavior, and immunity 2000;14(4):288-304.
2000: Martin E R; Lai E H; Gilbert J R; Rogala A R; Afshari A J; Riley J; Finch K L; Stevens J F; Livak K J; Slotterbeck B D; Slifer S H; Warren L L; Conneally P M; Schmechel D E; Purvis I; Pericak-Vance M A; Roses A D; Vance J M
SNPing away at complex diseases: analysis of single-nucleotide polymorphisms around APOE in Alzheimer disease.
American journal of human genetics 2000;67(2):383-94.
2000: Laskowitz D T; Lee D M; Schmechel D; Staats H F
Altered immune responses in apolipoprotein E-deficient mice.
Journal of lipid research 2000;41(4):613-20.
2000: Martin E R; Gilbert J R; Lai E H; Riley J; Rogala A R; Slotterbeck B D; Sipe C A; Grubber J M; Warren L L; Conneally P M; Saunders A M; Schmechel D E; Purvis I; Pericak-Vance M A; Roses A D; Vance J M
Analysis of association at single nucleotide polymorphisms in the APOE region.
Genomics 2000;63(1):7-12.
1999: Hulette C M; Pericak-Vance M A; Roses A D; Schmechel D E; Yamaoka L H; Gaskell P C; Welsh-Bohmer K A; Crowther R A; Spillantini M G
Neuropathological features of frontotemporal dementia and parkinsonism linked to chromosome 17q21-22 (FTDP-17): Duke Family 1684.
Journal of neuropathology and experimental neurology 1999;58(8):859-66.
1999: Levin E D; Simon B B; Schmechel D E; Glasgow H B; Deamer-Melia N J; Burkholder J M; Moser V C; Jensen K; Harry G J
Pfiesteria toxin and learning performance.
Neurotoxicology and teratology 1999;21(3):215-21.
1999: Rogaeva E A; Premkumar S; Grubber J; Serneels L; Scott W K; Kawarai T; Song Y; Hill D L; Abou-Donia S M; Martin E R; Vance J J; Yu G; Orlacchio A; Pei Y; Nishimura M; Supala A; Roberge B; Saunders A M; Roses A D; Schmechel D; Crane-Gatherum A; Sorbi S; Bruni A; Small G W; Conneally P M; Haines J L; Van Leuven F; St George-Hyslop P H; Farrer L A; Pericak-Vance M A
An alpha-2-macroglobulin insertion-deletion polymorphism in Alzheimer disease.
Nature genetics 1999;22(1):19-22.
1999: Xu P T; Schmechel D; Qiu H L; Herbstreith M; Rothrock-Christian T; Eyster M; Roses A D; Gilbert J R
Sialylated human apolipoprotein E (apoEs) is preferentially associated with neuron-enriched cultures from APOE transgenic mice.
Neurobiology of disease 1999;6(1):63-75.
1999: Xu P T; Gilbert J R; Qiu H L; Ervin J; Rothrock-Christian T R; Hulette C; Schmechel D E
Specific regional transcription of apolipoprotein E in human brain neurons.
The American journal of pathology 1999;154(2):601-11.
1998: Einstein G; Patel V; Bautista P; Kenna M; Melone L; Fader R; Karson K; Mann S; Saunders A M; Hulette C; Mash D; Roses A D; Schmechel D E
Intraneuronal ApoE in human visual cortical areas reflects the staging of Alzheimer disease pathology.
Journal of neuropathology and experimental neurology 1998;57(12):1190-201.
1998: Xu P T; Gilbert J R; Qiu H L; Rothrock-Christian T; Settles D L; Roses A D; Schmechel D E
Regionally specific neuronal expression of human APOE gene in transgenic mice.
Neuroscience letters 1998;246(2):65-8.
1998: Sheng H; Laskowitz D T; Bennett E; Schmechel D E; Bart R D; Saunders A M; Pearlstein R D; Roses A D; Warner D S
Apolipoprotein E isoform-specific differences in outcome from focal ischemia in transgenic mice.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1998;18(4):361-6.
1998: Laskowitz D T; Matthew W D; Bennett E R; Schmechel D; Herbstreith M H; Goel S; McMillian M K
Endogenous apolipoprotein E suppresses LPS-stimulated microglial nitric oxide production.
Neuroreport 1998;9(4):615-8.
1998: Roses A D; Gilbert J; Xu P T; Sullivan P; Popko B; Burkhart D S; Christian-Rothrock T; Saunders A M; Maeda N; Schmechel D E
Cis-acting human ApoE tissue expression element is associated with human pattern of intraneuronal ApoE in transgenic mice.
Neurobiology of aging 1998;19(1 Suppl):S53-8.
1997: Levin E D; Schmechel D E; Burkholder J B; Deamer-Melia N J; Moser V C; Harry G J
Persisting learning deficits in rats after exposure to Pfiesteria piscicida.
Environmental health perspectives 1997;105(12):1320-5.
1997: Piantadosi C A; Zhang J; Levin E D; Folz R J; Schmechel D E
Apoptosis and delayed neuronal damage after carbon monoxide poisoning in the rat.
Experimental neurology 1997;147(1):103-14.
1996: Yamaoka L H; Welsh-Bohmer K A; Hulette C M; Gaskell P C; Murray M; Rimmler J L; Helms B R; Guerra M; Roses A D; Schmechel D E; Pericak-Vance M A
Linkage of frontotemporal dementia to chromosome 17: clinical and neuropathological characterization of phenotype.
American journal of human genetics 1996;59(6):1306-12.
1996: Schmechel D E; Burkhart D S; Ange R; Izard M K
Cholinergic axonal dystrophy and mitochondrial pathology in prosimian primates.
Experimental neurology 1996;142(1):111-27.
1996: Lane S C; Jolly R D; Schmechel D E; Alroy J; Boustany R M
Apoptosis as the mechanism of neurodegeneration in Batten's disease.
Journal of neurochemistry 1996;67(2):677-83.
1996: Saunders A M; Hulette O; Welsh-Bohmer K A; Schmechel D E; Crain B; Burke J R; Alberts M J; Strittmatter W J; Breitner J C; Rosenberg C
Specificity, sensitivity, and predictive value of apolipoprotein-E genotyping for sporadic Alzheimer's disease.
Lancet 1996;348(9020):90-3.
1996: Roses A D; Einstein G; Gilbert J; Goedert M; Han S H; Huang D; Hulette C; Masliah E; Pericak-Vance M A; Saunders A M; Schmechel D E; Strittmatter W J; Weisgraber K H; Xi P T
Morphological, biochemical, and genetic support for an apolipoprotein E effect on microtubular metabolism.
Annals of the New York Academy of Sciences 1996;777():146-57.
1996: Xu P T; Schmechel D; Rothrock-Christian T; Burkhart D S; Qiu H L; Popko B; Sullivan P; Maeda N; Saunders A M; Roses A D; Gilbert J R
Human apolipoprotein E2, E3, and E4 isoform-specific transgenic mice: human-like pattern of glial and neuronal immunoreactivity in central nervous system not observed in wild-type mice.
Neurobiology of disease 1996;3(3):229-45.
1995: Graffagnino C; Herbstreith M H; Schmechel D E; Levy E; Roses A D; Alberts M J
Cystatin C mutation in an elderly man with sporadic amyloid angiopathy and intracerebral hemorrhage.
Stroke; a journal of cerebral circulation 1995;26(11):2190-3.
1995: Corder E H; Saunders A M; Strittmatter W J; Schmechel D E; Gaskell P C; Rimmler J B; Locke P A; Conneally P M; Schmader K E; Tanzi R E
Apolipoprotein E, survival in Alzheimer's disease patients, and the competing risks of death and Alzheimer's disease.
Neurology 1995;45(7):1323-8.
1995: Roses A D; Saunders A M; Corder E H; Pericak-Vance M A; Han S H; Einstein G; Hulette C; Schmechel D E; Holsti M; Huang D
Influence of the susceptibility genes apolipoprotein E-epsilon 4 and apolipoprotein E-epsilon 2 on the rate of disease expressivity of late-onset Alzheimer's disease.
Arzneimittel-Forschung 1995;45(3A):413-7.
1995: Roses A D; Saunders A M; Alberts M A; Strittmatter W J; Schmechel D; Gorder E; Pericak-Vance M A
Apolipoprotein E E4 allele and risk of dementia.
JAMA : the journal of the American Medical Association 1995;273(5):374-5; author reply 375-6.
1995: Corder E H; Saunders A M; Strittmatter W J; Schmechel D E; Gaskell P C; Roses A D; Pericak-Vance M A; Small G W; Haines J L
The apolipoprotein E E4 allele and sex-specific risk of Alzheimer's disease.
JAMA : the journal of the American Medical Association 1995;273(5):373-4.
1995: Roses A D; Saunders A M; Strittmatter W J; Schmechel D E; Pericak-Vance M A; Hyman B
Apolipoprotein E in Creutzfeldt-Jacob disease.
Lancet 1995;345(8941):69.
1994: Strittmatter W J; Saunders A M; Goedert M; Weisgraber K H; Dong L M; Jakes R; Huang D Y; Pericak-Vance M; Schmechel D; Roses A D
Isoform-specific interactions of apolipoprotein E with microtubule-associated protein tau: implications for Alzheimer disease.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(23):11183-6.
1994: Huang D Y; Goedert M; Jakes R; Weisgraber K H; Garner C C; Saunders A M; Pericak-Vance M A; Schmechel D E; Roses A D; Strittmatter W J
Isoform-specific interactions of apolipoprotein E with the microtubule-associated protein MAP2c: implications for Alzheimer's disease.
Neuroscience letters 1994;182(1):55-8.
1994: Han S H; Einstein G; Weisgraber K H; Strittmatter W J; Saunders A M; Pericak-Vance M; Roses A D; Schmechel D E
Apolipoprotein E is localized to the cytoplasm of human cortical neurons: a light and electron microscopic study.
Journal of neuropathology and experimental neurology 1994;53(5):535-44.
1994: Sanan D A; Weisgraber K H; Russell S J; Mahley R W; Huang D; Saunders A; Schmechel D; Wisniewski T; Frangione B; Roses A D
Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3.
The Journal of clinical investigation 1994;94(2):860-9.
1994: Han S H; Hulette C; Saunders A M; Einstein G; Pericak-Vance M; Strittmatter W J; Roses A D; Schmechel D E
Apolipoprotein E is present in hippocampal neurons without neurofibrillary tangles in Alzheimer's disease and in age-matched controls.
Experimental neurology 1994;128(1):13-26.
1994: Corder E H; Saunders A M; Risch N J; Strittmatter W J; Schmechel D E; Gaskell P C; Rimmler J B; Locke P A; Conneally P M; Schmader K E
Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease.
Nature genetics 1994;7(2):180-4.
1994: Roses A D; Strittmatter W J; Pericak-Vance M A; Corder E H; Saunders A M; Schmechel D E
Clinical application of apolipoprotein E genotyping to Alzheimer's disease.
Lancet 1994;343(8912):1564-5.
1994: Roses A D; Pericak-Vance M A; Saunders A M; Schmechel D; Goldgaber D; Strittmatter W
Complex genetic disease: can genetic strategies in Alzheimer's disease and new genetic mechanisms be applied to epilepsy?
Epilepsia 1994;35 Suppl 1():S20-8.
1993: Schmechel D E; Saunders A M; Strittmatter W J; Crain B J; Hulette C M; Joo S H; Pericak-Vance M A; Goldgaber D; Roses A D
Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(20):9649-53.
1993: Strittmatter W J; Weisgraber K H; Huang D Y; Dong L M; Salvesen G S; Pericak-Vance M; Schmechel D; Saunders A M; Goldgaber D; Roses A D
Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(17):8098-102.
1993: Goldgaber D; Schwarzman A I; Bhasin R; Gregori L; Schmechel D; Saunders A M; Roses A D; Strittmatter W J
Sequestration of amyloid beta-peptide.
Annals of the New York Academy of Sciences 1993;695():139-43.
1993: Saunders A M; Strittmatter W J; Schmechel D; George-Hyslop P H; Pericak-Vance M A; Joo S H; Rosi B L; Gusella J F; Crapper-MacLachlan D R; Alberts M J
Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease.
Neurology 1993;43(8):1467-72.
1993: Corder E H; Saunders A M; Strittmatter W J; Schmechel D E; Gaskell P C; Small G W; Roses A D; Haines J L; Pericak-Vance M A
Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families.
Science (New York, N.Y.) 1993;261(5123):921-3.
1993: Strittmatter W J; Saunders A M; Schmechel D; Pericak-Vance M; Enghild J; Salvesen G S; Roses A D
Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(5):1977-81.
1993: Diamond I T; Fitzpatrick D; Schmechel D
Calcium binding proteins distinguish large and small cells of the ventral posterior and lateral geniculate nuclei of the prosimian galago and the tree shrew (Tupaia belangeri).
Proceedings of the National Academy of Sciences of the United States of America 1993;90(4):1425-9.
1991: Schmechel D E
New approaches to therapy for neurodegenerative diseases.
Southern medical journal 1991;84(5 Suppl 1):S11-23.
1990: Goldgaber D; Schmechel D E
Expression of the amyloid beta-protein precursor gene.
Advances in neurology 1990;51():163-9.
1988: Schmechel D E; Goldgaber D; Burkhart D S; Gilbert J R; Gajdusek D C; Roses A D
Cellular localization of messenger RNA encoding amyloid-beta-protein in normal tissue and in Alzheimer disease.
Alzheimer disease and associated disorders 1988;2(2):96-111.
1987: Fitzpatrick D; Lund J S; Schmechel D E; Towles A C
Distribution of GABAergic neurons and axon terminals in the macaque striate cortex.
The Journal of comparative neurology 1987;264(1):73-91.
1987: Schmechel D E; Marangos P J; Martin B M; Winfield S; Burkhart D S; Roses A D; Ginns E I
Localization of neuron-specific enolase (NSE) mRNA in human brain.
Neuroscience letters 1987;76(2):233-8.
1987: Heyman A; Schmechel D; Wilkinson W; Rogers H; Krishnan R; Holloway D; Schultz K; Gwyther L; Peoples R; Utley C
Failure of long term high-dose lecithin to retard progression of early-onset Alzheimer's disease.
Journal of neural transmission. Supplementum 1987;24():279-86.
1984: Penny G R; Conley M; Schmechel D E; Diamond I T
The distribution of glutamic acid decarboxylase immunoreactivity in the diencephalon of the opossum and rabbit.
The Journal of comparative neurology 1984;228(1):38-56.
1984: Fitzpatrick D; Penny G R; Schmechel D E
Glutamic acid decarboxylase-immunoreactive neurons and terminals in the lateral geniculate nucleus of the cat.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1984;4(7):1809-29.
1983: Heyman A; Wilkinson W E; Hurwitz B J; Schmechel D; Sigmon A H; Weinberg T; Helms M J; Swift M
Alzheimer's disease: genetic aspects and associated clinical disorders.
Annals of neurology 1983;14(5):507-15.
1983: Penny G R; Fitzpatrick D; Schmechel D E; Diamond I T
Glutamic acid decarboxylase-immunoreactive neurons and horseradish peroxidase-labeled projection neurons in the ventral posterior nucleus of the cat and Galago senegalensis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1983;3(9):1868-87.

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