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Kurt Schmidt

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Gerald Wölkart; M V Wenzl; Heike Stessel; Matteo Beretta; N Maeda; Bernd Mayer; Kurt Schmidt; Astrid Schrammel
Tolerance to nitroglycerin through proteasomal down-regulation of aldehyde dehydrogenase-2 in a genetic mouse model of ascorbate deficiency.
Kurt Schmidt; Johannes-Peter Stasch; Ernst R Werner; Antonius C F Gorren; Bernd Kolesnik; Andrea Neubauer; Bernd Mayer
Tetrahydrobiopterin protects soluble guanylate cyclase against oxidative inactivation.
Matteo Beretta; Martina Griesberger; Frank R Heinzel; Sepp D Kohlwein; Regina Neubauer; Michael Sacherer; Michaela Schernthaner; Kurt Schmidt; Gerald Wölkart; Bernd Mayer
Vascular bioactivation of nitroglycerin is catalyzed by cytosolic aldehyde dehydrogenase-2.

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2013: Gerald Wölkart; M V Wenzl; Heike Stessel; Matteo Beretta; N Maeda; Bernd Mayer; Kurt Schmidt; Astrid Schrammel
Tolerance to nitroglycerin through proteasomal down-regulation of aldehyde dehydrogenase-2 in a genetic mouse model of ascorbate deficiency.
British journal of pharmacology 2013;168(8):1868-77.
2012: Kurt Schmidt; Johannes-Peter Stasch; Ernst R Werner; Antonius C F Gorren; Bernd Kolesnik; Andrea Neubauer; Bernd Mayer
Tetrahydrobiopterin protects soluble guanylate cyclase against oxidative inactivation.
Molecular pharmacology 2012;82(3):420-7.
2012: Matteo Beretta; Martina Griesberger; Frank R Heinzel; Sepp D Kohlwein; Regina Neubauer; Michael Sacherer; Michaela Schernthaner; Kurt Schmidt; Gerald Wölkart; Bernd Mayer
Vascular bioactivation of nitroglycerin is catalyzed by cytosolic aldehyde dehydrogenase-2.
Circulation research 2012;110(3):385-93.
2011: Martina Griesberger; Alexander Kollau; Gerald Wölkart; M Verena Wenzl; Matteo Beretta; Michael Russwurm; Doris Koesling; Kurt Schmidt; Antonius C F Gorren; Bernd Mayer
Bioactivation of pentaerythrityl tetranitrate by mitochondrial aldehyde dehydrogenase.
Molecular pharmacology 2011;79(3):541-8.
2010: Kurt Schmidt; Jens Martens-Lobenhoffer; Andreas Meinitzer; Wolfgang F Graier; Christina M Torres; Richard C Venema; Bernd Mayer
Activation of endothelial nitric oxide synthase by the pro-apoptotic drug embelin: Striking discrepancy between nitric oxide-mediated cyclic GMP accumulation and L-citrulline formation.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2010;22(4):281-9.
2010: Matteo Beretta; Antonius C F Gorren; M Verena Wenzl; Robert Weis; Michael Russwurm; Doris Koesling; Kurt Schmidt; Bernd Mayer
Characterization of the East Asian variant of aldehyde dehydrogenase-2: bioactivation of nitroglycerin and effects of Alda-1.
The Journal of biological chemistry 2010;285(2):943-52.
2010: Claudia Meda; Christian Plank; Olga Mykhaylyk; Kurt Schmidt; Bernd Mayer
Effects of statins on nitric oxide/cGMP signaling in human umbilical vein endothelial cells.
Pharmacological reports : PR 2010;62(1):100-12.
2010: Kurt Schmidt; Margit Rehn; Heike Stessel; Gerald Wölkart; Bernd Mayer
Evidence against tetrahydrobiopterin depletion of vascular tissue exposed to nitric oxide/superoxide or nitroglycerin.
Free radical biology & medicine 2010;48(1):145-52.
2009: Andreas Zeller; M Verena Wenzl; Matteo Beretta; Heike Stessel; Michael Russwurm; Doris Koesling; Kurt Schmidt; Bernd Mayer
Mechanisms underlying activation of soluble guanylate cyclase by the nitroxyl donor Angeli's salt.
Molecular pharmacology 2009;76(5):1115-22.
2009: M V Wenzl; Gerald Wölkart; Heike Stessel; Matteo Beretta; Kurt Schmidt; Bernd Mayer
Different effects of ascorbate deprivation and classical vascular nitrate tolerance on aldehyde dehydrogenase-catalysed bioactivation of nitroglycerin.
British journal of pharmacology 2009;156(8):1248-55.
2009: Bernd Mayer; Andrei L Kleschyov; Heike Stessel; Michael Russwurm; Thomas Münzel; Doris Koesling; Kurt Schmidt
Inactivation of soluble guanylate cyclase by stoichiometric S-nitrosation.
Molecular pharmacology 2009;75(4):886-91.
2009: Alexander Kollau; Matteo Beretta; Michael Russwurm; Doris Koesling; Wing Ming Keung; Kurt Schmidt; Bernd Mayer
Mitochondrial nitrite reduction coupled to soluble guanylate cyclase activation: lack of evidence for a role in the bioactivation of nitroglycerin.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2009;20(1):53-60.
2008: Matteo Beretta; Astrid Sottler; Kurt Schmidt; Bernd Mayer; Antonius C F Gorren
Partially irreversible inactivation of mitochondrial aldehyde dehydrogenase by nitroglycerin.
The Journal of biological chemistry 2008;283(45):30735-44.
2008: Gerald Wölkart; M Verena Wenzl; Matteo Beretta; Heike Stessel; Kurt Schmidt; Bernd Mayer
Vascular tolerance to nitroglycerin in ascorbate deficiency.
Cardiovascular research 2008;79(2):304-12.
2008: Matteo Beretta; Karl Gruber; Alexander Kollau; Michael Russwurm; Doris Koesling; Walter Goessler; Wing Ming Keung; Kurt Schmidt; Bernd Mayer
Bioactivation of nitroglycerin by purified mitochondrial and cytosolic aldehyde dehydrogenases.
The Journal of biological chemistry 2008;283(26):17873-80.
2007: Alexander Kollau; Matteo Beretta; Antonius C F Gorren; Michael Russwurm; Doris Koesling; Kurt Schmidt; Bernd Mayer
Bioactivation of nitroglycerin by ascorbate.
Molecular pharmacology 2007;72(1):191-6.
2006: Marc Pignitter; Antonius C F Gorren; Saviana Nedeianu; Kurt Schmidt; Bernd Mayer
Inefficient spin trapping of superoxide in the presence of nitric-oxide: implications for studies on nitric-oxide synthase uncoupling.
Free radical biology & medicine 2006;41(3):455-63.
2005: Antonius C F Gorren; Michael Russwurm; Alexander Kollau; Doris Koesling; Kurt Schmidt; Bernd Mayer
Effects of nitroglycerin/L-cysteine on soluble guanylate cyclase: evidence for an activation/inactivation equilibrium controlled by nitric oxide binding and haem oxidation.
The Biochemical journal 2005;390(Pt 2):625-31.
2005: Alexander Kollau; Alexandra Hofer; Michael Russwurm; Doris Koesling; Wing Ming Keung; Kurt Schmidt; Friedrich Brunner; Bernd Mayer
Contribution of aldehyde dehydrogenase to mitochondrial bioactivation of nitroglycerin: evidence for the activation of purified soluble guanylate cyclase through direct formation of nitric oxide.
The Biochemical journal 2005;385(Pt 3):769-77.
2004: Kurt Schmidt; Bernd Mayer
Consumption of nitric oxide by endothelial cells: evidence for the involvement of a NAD(P)H-, flavin- and heme-dependent dioxygenase reaction.
FEBS letters 2004;577(1-2):199-204.
2004: Rüdiger Wippel; Margit Rehn; Antonius C F Gorren; Kurt Schmidt; Bernd Mayer
Interference of the polyphenol epicatechin with the biological chemistry of nitric oxide- and peroxynitrite-mediated reactions.
Biochemical pharmacology 2004;67(7):1285-95.
2003: Astrid Schrammel; Antonius C F Gorren; Kurt Schmidt; Silvia Pfeiffer; Bernd Mayer
S-nitrosation of glutathione by nitric oxide, peroxynitrite, and (*)NO/O(2)(*-).
Free radical biology & medicine 2003;34(8):1078-88.
2003: Hans-Jörg Habisch; Antonius C F Gorren; Haiying Liang; Richard C Venema; John Parkinson; Kurt Schmidt; Bernd Mayer
Pharmacological interference with dimerization of human neuronal nitric-oxide synthase expressed in adenovirus-infected DLD-1 cells.
Molecular pharmacology 2003;63(3):682-9.
2003: Regina Golser; Antonius C F Gorren; Bernd Mayer; Kurt Schmidt
Functional characterization of Glu298Asp mutant human endothelial nitric oxide synthase purified from a yeast expression system.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2003;8(1):7-14.
2002: Baskaran Thyagarajan; Roland Malli; Kurt Schmidt; Wolfgang F. Graier; Klaus Groschner
Nitric oxide inhibits capacitative Ca2+ entry by suppression of mitochondrial Ca2+ handling.
British journal of pharmacology 2002;137(6):821-30.
2002: Antonius C F Gorren; Kurt Schmidt; Bernd Mayer
Binding of L-arginine and imidazole suggests heterogeneity of rat brain neuronal nitric oxide synthase.
Biochemistry 2002;41(24):7819-29.
2002: Sabine Wagner; Klaus Groschner; Bernd Mayer; Kurt Schmidt
Desensitization of endothelial nitric oxide synthase by receptor agonists.
The Biochemical journal 2002;364(Pt 3):863-8.
2002: Kurt Schmidt; Hanan D Gibraeil; Bernd Mayer
Lack of involvement of extracellular signal-regulated kinase (ERK) in the agonist-induced endothelial nitric oxide synthesis.
Biochemical pharmacology 2002;63(6):1137-42.
2001: Silvia Pfeiffer; Achim Lass; Kurt Schmidt; Bernd Mayer
Protein tyrosine nitration in mouse peritoneal macrophages activated in vitro and in vivo: evidence against an essential role of peroxynitrite.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(13):2355-64.
2001: Kurt Schmidt; Penelope Andrew; Astrid Schrammel; Klaus Groschner; V Schmitz; Georg Kojda; Bernd Mayer
Comparison of neuronal and endothelial isoforms of nitric oxide synthase in stably transfected HEK 293 cells.
American journal of physiology. Heart and circulatory physiology 2001;281(5):H2053-61.
2001: Silvia Pfeiffer; Achim Lass; Kurt Schmidt; Bernd Mayer
Protein tyrosine nitration in cytokine-activated murine macrophages. Involvement of a peroxidase/nitrite pathway rather than peroxynitrite.
The Journal of biological chemistry 2001;276(36):34051-8.
2001: Antonius C F Gorren; Andreas J Kungl; Kurt Schmidt; Ernst R Werner; Bernd Mayer
Electrochemistry of pterin cofactors and inhibitors of nitric oxide synthase.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2001;5(2):176-86.
2001: Kurt Schmidt; Astrid Schrammel; Doris Koesling; Bernd Mayer
Molecular mechanisms involved in the synergistic activation of soluble guanylyl cyclase by YC-1 and nitric oxide in endothelial cells.
Molecular pharmacology 2001;59(2):220-4.
2000: B Hemmens; Walter Goessler; Kurt Schmidt; Bernd Mayer
Role of bound zinc in dimer stabilization but not enzyme activity of neuronal nitric-oxide synthase.
The Journal of biological chemistry 2000;275(46):35786-91.
2000: Astrid Schrammel; Doris Koesling; Kurt Schmidt; Bernd Mayer
Inhibition of purified soluble guanylyl cyclase by L-ascorbic acid.
Cardiovascular research 2000;47(3):602-8.
2000: Ernst R Werner; Hans-Jörg Habisch; Antonius C F Gorren; Kurt Schmidt; L Canevari; Gabriele Werner-Felmayer; Bernd Mayer
Contrasting effects of N5-substituted tetrahydrobiopterin derivatives on phenylalanine hydroxylase, dihydropteridine reductase and nitric oxide synthase.
The Biochemical journal 2000;348 Pt 3():579-83.
2000: Antonius C F Gorren; Astrid Schrammel; C Riethmüller; Kurt Schmidt; Doris Koesling; Ernst R Werner; Bernd Mayer
Nitric oxide-induced autoinhibition of neuronal nitric oxide synthase in the presence of the autoxidation-resistant pteridine 5-methyltetrahydrobiopterin.
The Biochemical journal 2000;347(Pt 2):475-84.
2000: Silvia Pfeiffer; Kurt Schmidt; Bernd Mayer
Dityrosine formation outcompetes tyrosine nitration at low steady-state concentrations of peroxynitrite. Implications for tyrosine modification by nitric oxide/superoxide in vivo.
The Journal of biological chemistry 2000;275(9):6346-52.
2000: Regina Golser; Antonius C F Gorren; A Leber; Penelope Andrew; Hans-Jörg Habisch; Ernst R Werner; Kurt Schmidt; Richard C Venema; Bernd Mayer
Interaction of endothelial and neuronal nitric-oxide synthases with the bradykinin B2 receptor. Binding of an inhibitory peptide to the oxygenase domain blocks uncoupled NADPH oxidation.
The Journal of biological chemistry 2000;275(8):5291-6.
1999: A Leber; B Hemmens; B Klösch; Walter Goessler; G Raber; Bernd Mayer; Kurt Schmidt
Characterization of recombinant human endothelial nitric-oxide synthase purified from the yeast Pichia pastoris.
The Journal of biological chemistry 1999;274(53):37658-64.
1999: M Teubl; Klaus Groschner; Sepp D Kohlwein; Bernd Mayer; Kurt Schmidt
Na(+)/Ca(2+) exchange facilitates Ca(2+)-dependent activation of endothelial nitric-oxide synthase.
The Journal of biological chemistry 1999;274(41):29529-35.
1999: C Riethmüller; Antonius C F Gorren; Eva Pitters; B Hemmens; Hans-Jörg Habisch; S J Heales; Kurt Schmidt; Ernst R Werner; Bernd Mayer
Activation of neuronal nitric-oxide synthase by the 5-methyl analog of tetrahydrobiopterin. Functional evidence against reductive oxygen activation by the pterin cofactor.
The Journal of biological chemistry 1999;274(23):16047-51.
1999: K Posch; Kurt Schmidt; Wolfgang F. Graier
Selective stimulation of L-arginine uptake contributes to shear stress-induced formation of nitric oxide.
Life sciences 1999;64(8):663-70.
1999: Kurt Schmidt; Gabriele Werner-Felmayer; Bernd Mayer; Ernst R Werner
Preferential inhibition of inducible nitric oxide synthase in intact cells by the 4-amino analogue of tetrahydrobiopterin.
European journal of biochemistry / FEBS 1999;259(1-2):25-31.
1998: Astrid Schrammel; Antonius C F Gorren; D J Stuehr; Kurt Schmidt; Bernd Mayer
Isoform-specific effects of salts on nitric oxide synthase activity.
Biochimica et biophysica acta 1998;1387(1-2):257-63.
1998: B Hemmens; S Woschitz; Eva Pitters; B Klösch; C Völker; Kurt Schmidt; Bernd Mayer
The protein inhibitor of neuronal nitric oxide synthase (PIN): characterization of its action on pure nitric oxide synthases.
FEBS letters 1998;430(3):397-400.
1998: Astrid Schrammel; Silvia Pfeiffer; Kurt Schmidt; Doris Koesling; Bernd Mayer
Activation of soluble guanylyl cyclase by the nitrovasodilator 3-morpholinosydnonimine involves formation of S-nitrosoglutathione.
Molecular pharmacology 1998;54(1):207-12.
1998: B Hemmens; Antonius C F Gorren; Kurt Schmidt; Ernst R Werner; Bernd Mayer
Haem insertion, dimerization and reactivation of haem-free rat neuronal nitric oxide synthase.
The Biochemical journal 1998;332 ( Pt 2)():337-42.
1998: Antonius C F Gorren; Astrid Schrammel; Kurt Schmidt; Bernd Mayer
Effects of pH on the structure and function of neuronal nitric oxide synthase.
The Biochemical journal 1998;331 ( Pt 3)():801-7.
1998: Silvia Pfeiffer; Astrid Schrammel; Kurt Schmidt; Bernd Mayer
Electrochemical determination of S-nitrosothiols with a Clark-type nitric oxide electrode.
Analytical biochemistry 1998;258(1):68-73.
1998: Silvia Pfeiffer; Astrid Schrammel; Doris Koesling; Kurt Schmidt; Bernd Mayer
Molecular actions of a Mn(III)Porphyrin superoxide dismutase mimetic and peroxynitrite scavenger: reaction with nitric oxide and direct inhibition of NO synthase and soluble guanylyl cyclase.
Molecular pharmacology 1998;53(4):795-800.
1998: Kurt Schmidt; Silvia Pfeiffer; Bernd Mayer
Reaction of peroxynitrite with HEPES or MOPS results in the formation of nitric oxide donors.
Free radical biology & medicine 1998;24(5):859-62.
1998: Bernd Mayer; Silvia Pfeiffer; Astrid Schrammel; Doris Koesling; Kurt Schmidt; Friedrich Brunner
A new pathway of nitric oxide/cyclic GMP signaling involving S-nitrosoglutathione.
The Journal of biological chemistry 1998;273(6):3264-70.
1998: Kurt Schmidt; W Desch; P Klatt; WR Kukovetz; Bernd Mayer
Release of NO from donor compounds: a mathematical model for calculation of NO concentrations in the presence of oxygen.
Methods in molecular biology (Clifton, N.J.) 1998;100():281-9.
1998: Kurt Schmidt; Bernd Mayer
Determination of NO with a Clark-type electrode.
Methods in molecular biology (Clifton, N.J.) 1998;100():101-9.
1997: S Pfeiffer; Antonius C F Gorren; Eva Pitters; Kurt Schmidt; Ernst R Werner; Bernd Mayer
Allosteric modulation of rat brain nitric oxide synthase by the pterin-site enzyme inhibitor 4-aminotetrahydrobiopterin.
The Biochemical journal 1997;328 ( Pt 2)():349-52.
1997: Bernd Mayer; C Wu; Antonius C F Gorren; S Pfeiffer; Kurt Schmidt; P Clark; D J Stuehr; Ernst R Werner
Tetrahydrobiopterin binding to macrophage inducible nitric oxide synthase: heme spin shift and dimer stabilization by the potent pterin antagonist 4-amino-tetrahydrobiopterin.
Biochemistry 1997;36(27):8422-7.
1997: Antonius C F Gorren; Astrid Schrammel; Kurt Schmidt; Bernd Mayer
Thiols and neuronal nitric oxide synthase: complex formation, competitive inhibition, and enzyme stabilization.
Biochemistry 1997;36(14):4360-6.
1997: B M List; B Klösch; C Völker; Antonius C F Gorren; W C Sessa; Ernst R Werner; WR Kukovetz; Kurt Schmidt; Bernd Mayer
Characterization of bovine endothelial nitric oxide synthase as a homodimer with down-regulated uncoupled NADPH oxidase activity: tetrahydrobiopterin binding kinetics and role of haem in dimerization.
The Biochemical journal 1997;323 ( Pt 1)():159-65.
1997: Kurt Schmidt; W Desch; P Klatt; WR Kukovetz; Bernd Mayer
Release of nitric oxide from donors with known half-life: a mathematical model for calculating nitric oxide concentrations in aerobic solutions.
Naunyn-Schmiedeberg's archives of pharmacology 1997;355(4):457-62.
1997: Silvia Pfeiffer; Antonius C F Gorren; Kurt Schmidt; Ernst R Werner; B Hansert; D Scott Bohle; Bernd Mayer
Metabolic fate of peroxynitrite in aqueous solution. Reaction with nitric oxide and pH-dependent decomposition to nitrite and oxygen in a 2:1 stoichiometry.
The Journal of biological chemistry 1997;272(6):3465-70.
1997: Bernd Mayer; Eva Pitters; S Pfeiffer; WR Kukovetz; Kurt Schmidt
A synthetic peptide corresponding to the putative dihydrofolate reductase domain of nitric oxide synthase inhibits uncoupled NADPH oxidation.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 1997;1(1):50-5.
1997: Silvia Pfeiffer; E Leopold; B Hemmens; Kurt Schmidt; Ernst R Werner; Bernd Mayer
Interference of carboxy-PTIO with nitric oxide- and peroxynitrite-mediated reactions.
Free radical biology & medicine 1997;22(5):787-94.
1996: Antonius C F Gorren; B M List; Astrid Schrammel; Eva Pitters; B Hemmens; Ernst R Werner; Kurt Schmidt; Bernd Mayer
Tetrahydrobiopterin-free neuronal nitric oxide synthase: evidence for two identical highly anticooperative pteridine binding sites.
Biochemistry 1996;35(51):16735-45.
1996: Astrid Schrammel; Doris Koesling; Antonius C F Gorren; M Chevion; Kurt Schmidt; Bernd Mayer
Inhibition of purified soluble guanylyl cyclase by copper ions.
Biochemical pharmacology 1996;52(7):1041-5.
1996: S Pfeiffer; E Leopold; Kurt Schmidt; Friedrich Brunner; Bernd Mayer
Inhibition of nitric oxide synthesis by NG-nitro-L-arginine methyl ester (L-NAME): requirement for bioactivation to the free acid, NG-nitro-L-arginine.
British journal of pharmacology 1996;118(6):1433-40.
1996: Astrid Schrammel; S Behrends; Kurt Schmidt; Doris Koesling; Bernd Mayer
Characterization of 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one as a heme-site inhibitor of nitric oxide-sensitive guanylyl cyclase.
Molecular pharmacology 1996;50(1):1-5.
1996: Antonius C F Gorren; Kurt Schmidt; Bernd Mayer
Decomposition of S-nitrosoglutathione in the presence of copper ions and glutathione.
Archives of biochemistry and biophysics 1996;330(2):219-28.
1996: Bernd Mayer; S Pfeiffer; E Leopold; J Müller; U Weser; Kurt Schmidt
Structural and functional analogs of CuZn superoxide dismutase inhibit rat brain nitric oxide synthase by interference with the reductase (diaphorase) domain.
Neuroscience letters 1996;209(3):169-72.
1996: B M List; P Klatt; Ernst R Werner; Kurt Schmidt; Bernd Mayer
Overexpression of neuronal nitric oxide synthase in insect cells reveals requirement of haem for tetrahydrobiopterin binding.
The Biochemical journal 1996;315 ( Pt 1)():57-63.
1996: P Klatt; S Pfeiffer; B M List; D Lehner; Otto Glatter; Hans Peter Bächinger; Ernst R Werner; Kurt Schmidt; Bernd Mayer
Characterization of heme-deficient neuronal nitric-oxide synthase reveals a role for heme in subunit dimerization and binding of the amino acid substrate and tetrahydrobiopterin.
The Journal of biological chemistry 1996;271(13):7336-42.
1996: Bernd Mayer; P Klatt; B M List; Christian Harteneck; Kurt Schmidt
Large-scale purification of rat brain nitric oxide synthase from baculovirus overexpression system.
Methods in enzymology 1996;268():420-7.
1996: P Klatt; Kurt Schmidt; Ernst R Werner; Bernd Mayer
Determination of nitric oxide synthase cofactors: heme, FAD, FMN, and tetrahydrobiopterin.
Methods in enzymology 1996;268():358-65.
1995: P Klatt; Kurt Schmidt; D Lehner; Otto Glatter; Hans Peter Bächinger; Bernd Mayer
Structural analysis of porcine brain nitric oxide synthase reveals a role for tetrahydrobiopterin and L-arginine in the formation of an SDS-resistant dimer.
The EMBO journal 1995;14(15):3687-95.
1995: Bernd Mayer; Astrid Schrammel; P Klatt; Doris Koesling; Kurt Schmidt
Peroxynitrite-induced accumulation of cyclic GMP in endothelial cells and stimulation of purified soluble guanylyl cyclase. Dependence on glutathione and possible role of S-nitrosation.
The Journal of biological chemistry 1995;270(29):17355-60.
1995: Kurt Schmidt; B M List; P Klatt; Bernd Mayer
Characterization of neuronal amino acid transporters: uptake of nitric oxide synthase inhibitors and implication for their biological effects.
Journal of neurochemistry 1995;64(4):1469-75.
1995: Bernd Mayer; P Klatt; Ernst R Werner; Kurt Schmidt
Kinetics and mechanism of tetrahydrobiopterin-induced oxidation of nitric oxide.
The Journal of biological chemistry 1995;270(2):655-9.
1994: Bernd Mayer; P Klatt; Ernst R Werner; Kurt Schmidt
Molecular mechanisms of inhibition of porcine brain nitric oxide synthase by the antinociceptive drug 7-nitro-indazole.
Neuropharmacology 1994;33(11):1253-9.
1994: Bernd Mayer; P Klatt; Ernst R Werner; Kurt Schmidt
Identification of imidazole as L-arginine-competitive inhibitor of porcine brain nitric oxide synthase.
FEBS letters 1994;350(2-3):199-202.
1994: Kurt Schmidt; P Klatt; Bernd Mayer
Reaction of peroxynitrite with oxyhaemoglobin: interference with photometrical determination of nitric oxide.
The Biochemical journal 1994;301 ( Pt 3)():645-7.
1994: Kurt Schmidt; P Klatt; Bernd Mayer
Uptake of nitric oxide synthase inhibitors by macrophage RAW 264.7 cells.
The Biochemical journal 1994;301 ( Pt 2)():313-6.
1994: P Klatt; M Schmid; E Leopold; Kurt Schmidt; Ernst R Werner; Bernd Mayer
The pteridine binding site of brain nitric oxide synthase. Tetrahydrobiopterin binding kinetics, specificity, and allosteric interaction with the substrate domain.
The Journal of biological chemistry 1994;269(19):13861-6.
1994: P Klatt; Kurt Schmidt; Friedrich Brunner; Bernd Mayer
Inhibitors of brain nitric oxide synthase. Binding kinetics, metabolism, and enzyme inactivation.
The Journal of biological chemistry 1994;269(3):1674-80.
1993: Bernd Mayer; Friedrich Brunner; Kurt Schmidt
Novel actions of methylene blue.
European heart journal 1993;14 Suppl I():22-6.
1993: Bernd Mayer; M Schmid; P Klatt; Kurt Schmidt
Reversible inactivation of endothelial nitric oxide synthase by NG-nitro-L-arginine.
FEBS letters 1993;333(1-2):203-6.
1993: P Klatt; Kurt Schmidt; G Uray; Bernd Mayer
Multiple catalytic functions of brain nitric oxide synthase. Biochemical characterization, cofactor-requirement, and the role of N omega-hydroxy-L-arginine as an intermediate.
The Journal of biological chemistry 1993;268(20):14781-7.
1993: Bernd Mayer; Friedrich Brunner; Kurt Schmidt
Inhibition of nitric oxide synthesis by methylene blue.
Biochemical pharmacology 1993;45(2):367-74.
1992: Bernd Mayer; P Klatt; E Böhme; Kurt Schmidt
Regulation of neuronal nitric oxide and cyclic GMP formation by Ca2+.
Journal of neurochemistry 1992;59(6):2024-9.
1992: P Klatt; Kurt Schmidt; Bernd Mayer
Brain nitric oxide synthase is a haemoprotein.
The Biochemical journal 1992;288 ( Pt 1)():15-7.
1992: Wolfgang F. Graier; Klaus Groschner; Kurt Schmidt; WR Kukovetz
SK&F 96365 inhibits histamine-induced formation of endothelium-derived relaxing factor in human endothelial cells.
Biochemical and biophysical research communications 1992;186(3):1539-45.
1992: Kurt Schmidt; P Klatt; Wolfgang F. Graier; Gerhard Kostner; WR Kukovetz
High-density lipoprotein antagonizes the inhibitory effects of oxidized low-density lipoprotein and lysolecithin on soluble guanylyl cyclase.
Biochemical and biophysical research communications 1992;182(1):302-8.
1992: Kurt Schmidt; E R Werner; Bernd Mayer; H Wachter; WR Kukovetz
Tetrahydrobiopterin-dependent formation of endothelium-derived relaxing factor (nitric oxide) in aortic endothelial cells.
The Biochemical journal 1992;281 ( Pt 2)():297-300.
1992: Wolfgang F. Graier; Kurt Schmidt; WR Kukovetz
Is the bradykinin-induced Ca2+ influx and the formation of endothelium-derived relaxing factor mediated by a G protein?
European journal of pharmacology 1992;225(1):43-9.
1992: Bernd Mayer; B Heinzel; P Klatt; M John; Kurt Schmidt; E Böhme
Nitric oxide synthase-catalyzed activation of oxygen and reduction of cytochromes: reaction mechanisms and possible physiological implications.
Journal of cardiovascular pharmacology 1992;20 Suppl 12():S54-6.
1991: WR Kukovetz; S Holzmann; Kurt Schmidt
Cellular mechanisms of action of therapeutic nitric oxide donors.
European heart journal 1991;12 Suppl E():16-24.
1991: Kurt Schmidt; Wolfgang F. Graier; Gerhard Kostner; Bernd Mayer; E Böhme; WR Kukovetz
Oxidized low-density lipoprotein antagonizes the activation of purified soluble guanylate cyclase by endothelium-derived relaxing factor but does not interfere with its biosynthesis.
Cellular signalling 1991;3(4):361-7.
1990: Kurt Schmidt; Wolfgang F. Graier; Gerhard Kostner; Bernd Mayer; WR Kukovetz
Activation of soluble guanylate cyclase by nitrovasodilators is inhibited by oxidized low-density lipoprotein.
Biochemical and biophysical research communications 1990;172(2):614-9.
1990: Wolfgang F. Graier; Kurt Schmidt; WR Kukovetz
Effect of sodium fluoride on cytosolic free Ca2(+)-concentrations and cGMP-levels in endothelial cells.
Cellular signalling 1990;2(4):369-75.
1990: Kurt Schmidt; Wolfgang F. Graier; WR Kukovetz
EDRF-formation increases cGMP-levels in cultured endothelial cells.
Advances in second messenger and phosphoprotein research 1990;24():455-60.
1989: Kurt Schmidt; Bernd Mayer; WR Kukovetz
Effect of calcium on endothelium-derived relaxing factor formation and cGMP levels in endothelial cells.
European journal of pharmacology 1989;170(3):157-66.
1989: Kurt Schmidt; WR Kukovetz
Mediation of the cardiac effects of forskolin by specific binding sites.
Journal of cardiovascular pharmacology 1989;13(3):353-60.