FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Laura Schmidt

Research Profile

Disorders

Chemicals & Drugs

Physiology

Concepts & Ideas

Living Beings

Mouse

Procedures

DNA Mutational Analysis

Co-author Network

Publications

TOP 3
Christopher J Ricketts; Laura S Schmidt; Brian Shuch; Ramaprasad Srinivasan; Catherine Stolle; Cathy D Vocke; Ming-Hui Wei; Youfeng Yang; Berton Zbar; Maria J Merino; Adam R Metwalli; Lindsay Middelton; Karel Pacak; Stephen E Pautler; James Peterson; Peter A Pinto; Gennady Bratslavsky; W Marston Linehan
Succinate dehydrogenase kidney cancer: an aggressive example of the Warburg effect in cancer.
Hisashi Hasumi; Yukiko Hasumi; Ying Huang; Robert M Hughes; Mara E Klein; Kunio Nagashima; Hyoungbin Oh; Laura S Schmidt; Shoichi Takikita; Masaya Baba; W Marston Linehan
Regulation of mitochondrial oxidative metabolism by tumor suppressor FLCN.
Masaya Baba; Paul Bible; Carme Gallego Gonzalez; Hisashi Hasumi; Yukiko Hasumi; Robert M Hughes; Jonathan Keller; Kyong-Rim Kieffer-Kwon; Mara E Klein; Stefan Kuchen; W Marston Linehan; Hyoungbin F Oh; Wolfgang Resch; Laura S Schmidt; Eileen Southon; Hyung Chan Suh; Hong-Wei Sun; Lino Tessarollo; Rafael Casellas
The folliculin-FNIP1 pathway deleted in human Birt-Hogg-Dubé syndrome is required for murine B-cell development.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Laura Schmidt (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: Christopher J Ricketts; Laura S Schmidt; Brian Shuch; Ramaprasad Srinivasan; Catherine Stolle; Cathy D Vocke; Ming-Hui Wei; Youfeng Yang; Berton Zbar; Maria J Merino; Adam R Metwalli; Lindsay Middelton; Karel Pacak; Stephen E Pautler; James Peterson; Peter A Pinto; Gennady Bratslavsky; W Marston Linehan
Succinate dehydrogenase kidney cancer: an aggressive example of the Warburg effect in cancer.
The Journal of urology 2012;188(6):2063-71.
2012: Hisashi Hasumi; Yukiko Hasumi; Ying Huang; Robert M Hughes; Mara E Klein; Kunio Nagashima; Hyoungbin Oh; Laura S Schmidt; Shoichi Takikita; Masaya Baba; W Marston Linehan
Regulation of mitochondrial oxidative metabolism by tumor suppressor FLCN.
Journal of the National Cancer Institute 2012;104(22):1750-64.
2012: Masaya Baba; Paul Bible; Carme Gallego Gonzalez; Hisashi Hasumi; Yukiko Hasumi; Robert M Hughes; Jonathan Keller; Kyong-Rim Kieffer-Kwon; Mara E Klein; Stefan Kuchen; W Marston Linehan; Hyoungbin F Oh; Wolfgang Resch; Laura S Schmidt; Eileen Southon; Hyung Chan Suh; Hong-Wei Sun; Lino Tessarollo; Rafael Casellas
The folliculin-FNIP1 pathway deleted in human Birt-Hogg-Dubé syndrome is required for murine B-cell development.
Blood 2012;120(6):1254-61.
2011: Lee E Moore; Marie Navratilova; Michael L Nickerson; Jessica Rinsky; Laura S Schmidt; Neonilia Szeszenia-Dabrowska; Jorge R Toro; Frederic M Waldman; David Zaridze; Vladimir Bencko; Paolo Boffetta; Paul Brennan; STEPHEN CHANOCK; Wong-Ho Chow; Summer S Han; Erich Jaeger; vladimir janout; Sara Karami; Helena Kollarova; Petra Lenz; W Marston Linehan; Dana Mates; Vsevolod Matveev; Maria Merino; Nathaniel Rothman
Von Hippel-Lindau (VHL) inactivation in sporadic clear cell renal cancer: associations with germline VHL polymorphisms and etiologic risk factors.
PLoS genetics 2011;7(10):e1002312.
2011: Jihane N Benhammou; Cathy D Vocke; Avni Santani; Laura S Schmidt; Masaya Baba; Kuniaki Seyama; Xiaolin Wu; Susana Korolevich; Katherine L Nathanson; Catherine A Stolle; W Marston Linehan
Identification of intragenic deletions and duplication in the FLCN gene in Birt-Hogg-Dubé syndrome.
Genes, chromosomes & cancer 2011;50(6):466-77.
2010: W Marston Linehan; Ramaprasad Srinivasan; Laura S Schmidt
The genetic basis of kidney cancer: a metabolic disease.
Nature reviews. Urology 2010;7(5):277-85.
2010: Seung-Beom Hong; HyoungBin Oh; Vladimir A Valera; Masaya Baba; Laura S Schmidt; W Marston Linehan
Inactivation of the FLCN tumor suppressor gene induces TFE3 transcriptional activity by increasing its nuclear localization.
PloS one 2010;5(12):e15793.
2010: Seung-Beom Hong; HyoungBin Oh; Vladimir A Valera; Jaime Stull; Duy-Tan Ngo; Masaya Baba; Maria J Merino; W Marston Linehan; Laura S Schmidt
Tumor suppressor FLCN inhibits tumorigenesis of a FLCN-null renal cancer cell line and regulates expression of key molecules in TGF-beta signaling.
Molecular cancer 2010;9():160.
2010: W Marston Linehan; Gennady Bratslavsky; Peter A Pinto; Laura S Schmidt; Len Neckers; Donald Bottaro; Ramaprasad Srinivasan
Molecular diagnosis and therapy of kidney cancer.
Annual review of medicine 2010;61():329-43.
2009: Yukiko Hasumi; Masaya Baba; Rieko Ajima; Hisashi Hasumi; Vladimir A Valera; Mara E Klein; Diana C Haines; Maria J Merino; Seung-Beom Hong; Terry P Yamaguchi; Laura S Schmidt; W Marston Linehan
Homozygous loss of BHD causes early embryonic lethality and kidney tumor development with activation of mTORC1 and mTORC2.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(44):18722-7.
2009: W Marston Linehan; Peter A Pinto; Gennady Bratslavsky; Elizabeth Pfaffenroth; Maria Merino; Cathy D Vocke; Jorge R Toro; Donald Bottaro; Len Neckers; Laura S Schmidt; Ramaprasad Srinivasan
Hereditary kidney cancer: unique opportunity for disease-based therapy.
Cancer 2009;115(10 Suppl):2252-61.
2009: H-C Jennifer Shen; Asha Adem; Kris Ylaya; Arianne Wilson; Mei He; Dominique Lorang; Stephen M Hewitt; Klaus Pechhold; David M Harlan; Irina A Lubensky; Laura S Schmidt; W Marston Linehan; Steven Libutti
Deciphering von Hippel-Lindau (VHL/Vhl)-associated pancreatic manifestations by inactivating Vhl in specific pancreatic cell populations.
PloS one 2009;4(4):e4897.
2008: Jorge R Toro; Ming-Hui Wei; Gladys Glenn; Michael Weinreich; Ousmane Toure; C Vocke; M Turner; Peter Choyke; Maria J Merino; P A Pinto; Seth M Steinberg; Laura S Schmidt; W Marston Linehan
BHD mutations, clinical and molecular genetic investigations of Birt-Hogg-Dubé syndrome: a new series of 50 families and a review of published reports.
Journal of medical genetics 2008;45(6):321-31.
2008: Hisashi Hasumi; Masaya Baba; Seung-Beom Hong; Yukiko Hasumi; Ying Huang; Masahiro Yao; Vladimir A Valera; W Marston Linehan; Laura S Schmidt
Identification and characterization of a novel folliculin-interacting protein FNIP2.
Gene 2008;415(1-2):60-7.
2008: Masaya Baba; Mutsuo Furihata; Seung-Beom Hong; Lino Tessarollo; Diana C Haines; Eileen Southon; Vishal Patel; Peter Igarashi; W Gregory Alvord; Robert Leighty; Masahiro Yao; Marcelino Bernardo; Lilia Ileva; Peter Choyke; Michelle B Warren; Berton Zbar; W Marston Linehan; Laura S Schmidt
Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys.
Journal of the National Cancer Institute 2008;100(2):140-54.
2007: Jorge R Toro; Stephen E Pautler; LAVETA STEWART; Gladys Glenn; Michael Weinreich; Ousmane Toure; Ming-Hui Wei; Laura S Schmidt; Lewis Davis; Berton Zbar; Peter Choyke; Seth M Steinberg; Dao Nguyen; W Marston Linehan
Lung cysts, spontaneous pneumothorax, and genetic associations in 89 families with Birt-Hogg-Dubé syndrome.
American journal of respiratory and critical care medicine 2007;175(10):1044-53.
2007: Berton Zbar; Gladys Glenn; Maria Merino; Lindsay Middelton; James Peterson; Jorge Toro; Jonathan Coleman; Peter Pinto; Laura S Schmidt; Peter Choyke; W Marston Linehan
Familial renal carcinoma: clinical evaluation, clinical subtypes and risk of renal carcinoma development.
The Journal of urology 2007;177(2):461-5; discussion 465.
2007: W Marston Linehan; Peter A Pinto; Ramaprasad Srinivasan; Maria Merino; Peter Choyke; Lynda Choyke; Jonathan Coleman; Jorge Toro; Gladys Glenn; Cathy D Vocke; Berton Zbar; Laura S Schmidt; Donald Bottaro; Len Neckers
Identification of the genes for kidney cancer: opportunity for disease-specific targeted therapeutics.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(2 Pt 2):671s-679s.
2006: Masaya Baba; Seung-Beom Hong; Nirmala Sharma; Michelle B Warren; Michael L Nickerson; Akihiro Iwamatsu; Dominic Esposito; William K Gillette; Ralph F Hopkins; James L Hartley; Mutsuo Furihata; Shinya Oishi; Wei Zhen; Terrence R Burke; W Marston Linehan; Laura S Schmidt; Berton Zbar
Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(42):15552-7.
2006: Shree R Singh; W Zhen; Zhiyu Zheng; Hong Wang; Su-Wan Oh; W Liu; Berton Zbar; Laura S Schmidt; Steven X Hou
The Drosophila homolog of the human tumor suppressor gene BHD interacts with the JAK-STAT and Dpp signaling pathways in regulating male germline stem cell maintenance.
Oncogene 2006;25(44):5933-41.
2006: Seung-Beom Hong; Mutsuo Furihata; Masaya Baba; Berton Zbar; Laura S Schmidt
Vascular defects and liver damage by the acute inactivation of the VHL gene during mouse embryogenesis.
Laboratory investigation; a journal of technical methods and pathology 2006;86(7):664-75.
2005: Cathy D Vocke; Youfeng Yang; Christian P Pavlovich; Laura S Schmidt; Michael L Nickerson; Carlos Torres-Cabala; Maria J Merino; McClellan Walther; Berton Zbar; W Marston Linehan
High frequency of somatic frameshift BHD gene mutations in Birt-Hogg-Dubé-associated renal tumors.
Journal of the National Cancer Institute 2005;97(12):931-5.
2005: Laura S Schmidt; Michael L Nickerson; Michelle B Warren; Gladys Glenn; Jorge R Toro; Maria J Merino; Maria L Turner; Peter L Choyke; Nirmala Sharma; James Peterson; Patrick Morrison; Eamonn R Maher; McClellan Walther; Berton Zbar; W Marston Linehan
Germline BHD-mutation spectrum and phenotype analysis of a large cohort of families with Birt-Hogg-Dubé syndrome.
American journal of human genetics 2005;76(6):1023-33.
2005: Kirsten K Youngren; Douglas Coveney; Xiaoning Peng; Chitralekha Bhattacharya; Laura S Schmidt; Michael L Nickerson; Bruce Lamb; Jian Min Deng; Richard R Behringer; Blanche Capel; Edward M Rubin; Joseph H Nadeau; Angabin Matin
The Ter mutation in the dead end gene causes germ cell loss and testicular germ cell tumours.
Nature 2005;435(7040):360-4.
2005: Christian P Pavlovich; Robert L Grubb; Kathleen Hurley; Gladys Glenn; Jorge Toro; Laura S Schmidt; Carlos Torres-Cabala; Maria J Merino; Berton Zbar; Peter Choyke; McClellan Walther; W Marston Linehan
Evaluation and management of renal tumors in the Birt-Hogg-Dubé syndrome.
The Journal of urology 2005;173(5):1482-6.
2004: Laura S Schmidt; Michael L Nickerson; Debora Angeloni; Gladys Glenn; McClellan Walther; Paul S Albert; Michelle B Warren; Peter L Choyke; Carlos Torres-Cabala; Maria J Merino; Joan Brunet; Victòria Bérez; Joan Borràs; Giovanni Sesia; Lindsay Middelton; John L Phillips; Catherine Stolle; Berton Zbar; Stephen E Pautler; W Marston Linehan
Early onset hereditary papillary renal carcinoma: germline missense mutations in the tyrosine kinase domain of the met proto-oncogene.
The Journal of urology 2004;172(4 Pt 1):1256-61.
2004: Michelle B Warren; Carlos Torres-Cabala; Maria L Turner; Maria J Merino; Vera Y Matrosova; Michael L Nickerson; Wenbin Ma; W Marston Linehan; Berton Zbar; Laura S Schmidt
Expression of Birt-Hogg-Dubé gene mRNA in normal and neoplastic human tissues.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2004;17(8):998-1011.
2004: Christian P Pavlovich; Laura S Schmidt
Searching for the hereditary causes of renal-cell carcinoma.
Nature reviews. Cancer 2004;4(5):381-93.
2004: Kazuo Okimoto; Junko Sakurai; Toshiyuki Kobayashi; Hiroaki Mitani; Youko Hirayama; Michael L Nickerson; Michelle B Warren; Berton Zbar; Laura S Schmidt; Okio Hino
A germ-line insertion in the Birt-Hogg-Dubé (BHD) gene gives rise to the Nihon rat model of inherited renal cancer.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(7):2023-7.
2003: Frode Lingaas; Kenine Comstock; Ewen F Kirkness; Anita Sørensen; Tone Aarskaug; Christophe Hitte; Michael L Nickerson; Lars Moe; Laura S Schmidt; Rachael Thomas; Matthew Breen; Francis Galibert; Berton Zbar; Elaine A Ostrander
A mutation in the canine BHD gene is associated with hereditary multifocal renal cystadenocarcinoma and nodular dermatofibrosis in the German Shepherd dog.
Human molecular genetics 2003;12(23):3043-53.
2003: Wenbin Ma; Lino Tessarollo; Seung-Beom Hong; Masaya Baba; Eileen Southon; Timothy C Back; Sally Spence; Corrinne G Lobe; Nirmala Sharma; Gregory W Maher; Svetlana Pack; Alexander O Vortmeyer; Chuanfa Guo; Berton Zbar; Laura S Schmidt
Hepatic vascular tumors, angiectasis in multiple organs, and impaired spermatogenesis in mice with conditional inactivation of the VHL gene.
Cancer research 2003;63(17):5320-8.
2003: Christian P Pavlovich; Laura S Schmidt; John L Phillips
The genetic basis of renal cell carcinoma.
The Urologic clinics of North America 2003;30(3):437-54, vii.
2003: Jorge R Toro; Michael L Nickerson; Ming-Hui Wei; Michelle B Warren; Gladys Glenn; Maria L Turner; LAVETA STEWART; Paul H Duray; Ousman Tourre; Nirmala Sharma; Peter Choyke; Pamela Stratton; Maria Merino; McClellan Walther; W Marston Linehan; Laura S Schmidt; Berton Zbar
Mutations in the fumarate hydratase gene cause hereditary leiomyomatosis and renal cell cancer in families in North America.
American journal of human genetics 2003;73(1):95-106.
2002: Michael L Nickerson; Michelle B Warren; Jorge R Toro; Vera Y Matrosova; Gladys Glenn; Maria L Turner; Paul H Duray; Maria Merino; Peter Choyke; Christian P Pavlovich; Nirmala Sharma; McClellan Walther; David Munroe; Rob Hill; Eamonn Maher; Cheryl Greenberg; Michael I Lerman; W Marston Linehan; Berton Zbar; Laura S Schmidt
Mutations in a novel gene lead to kidney tumors, lung wall defects, and benign tumors of the hair follicle in patients with the Birt-Hogg-Dubé syndrome.
Cancer cell 2002;2(2):157-64.
2001: Laura S Schmidt; Michelle B Warren; Michael L Nickerson; Gregor Weirich; Vera Y Matrosova; Jorge R Toro; Maria L Turner; Paul H Duray; Maria Merino; S Hewitt; Christian P Pavlovich; Gladys Glenn; C R Greenberg; W Marston Linehan; Berton Zbar
Birt-Hogg-Dubé syndrome, a genodermatosis associated with spontaneous pneumothorax and kidney neoplasia, maps to chromosome 17p11.2.
American journal of human genetics 2001;69(4):876-82.
2001: Michael L Nickerson; Michelle B Warren; Berton Zbar; Laura S Schmidt
Random mutagenesis-PCR to introduce alterations into defined DNA sequences for validation of SNP and mutation detection methods.
Human mutation 2001;17(3):210-9.
2000: Michael L Nickerson; Gregor Weirich; Berton Zbar; Laura S Schmidt
Signature-based analysis of MET proto-oncogene mutations using DHPLC.
Human mutation 2000;16(1):68-76.