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Pamela Blaikie

Research Profile

Chemicals & Drugs

Living Beings

Physiology

Anatomy

Disorders

Neovascularization, Pathologic

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Publications

TOP 3
Sotiris N Nikolopoulos; Pamela Blaikie; Toshiaki Yoshioka; Wenjun Guo; Claudia Puri; Carlo Tacchetti; Filippo G Giancotti
Targeted deletion of the integrin beta4 signaling domain suppresses laminin-5-dependent nuclear entry of mitogen-activated protein kinases and NF-kappaB, causing defects in epidermal growth and migration.
Sotiris N Nikolopoulos; Pamela Blaikie; Toshiaki Yoshioka; Wenjun Guo; Filippo G Giancotti
Integrin beta4 signaling promotes tumor angiogenesis.
Sharon Klein; Antonin R de Fougerolles; Pamela Blaikie; Leila Khan; Angela Pepe; Cynthia D Green; Victor E Koteliansky; Filippo G Giancotti
Alpha 5 beta 1 integrin activates an NF-kappa B-dependent program of gene expression important for angiogenesis and inflammation.

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All Publications

2005: Sotiris N Nikolopoulos; Pamela Blaikie; Toshiaki Yoshioka; Wenjun Guo; Claudia Puri; Carlo Tacchetti; Filippo G Giancotti
Targeted deletion of the integrin beta4 signaling domain suppresses laminin-5-dependent nuclear entry of mitogen-activated protein kinases and NF-kappaB, causing defects in epidermal growth and migration.
Molecular and cellular biology 2005;25(14):6090-102.
2004: Sotiris N Nikolopoulos; Pamela Blaikie; Toshiaki Yoshioka; Wenjun Guo; Filippo G Giancotti
Integrin beta4 signaling promotes tumor angiogenesis.
Cancer cell 2004;6(5):471-83.
2002: Sharon Klein; Antonin R de Fougerolles; Pamela Blaikie; Leila Khan; Angela Pepe; Cynthia D Green; Victor E Koteliansky; Filippo G Giancotti
Alpha 5 beta 1 integrin activates an NF-kappa B-dependent program of gene expression important for angiogenesis and inflammation.
Molecular and cellular biology 2002;22(16):5912-22.
2001: David Lyden; K Hattori; Sergio Dias; C Costa; Pamela Blaikie; Linda J Butros; Amy Chadburn; Beate Heissig; W Marks; Larry Witte; Y Wu; Daniel J Hicklin; Z Zhu; Neil R Hackett; Helen-Ann Brown Epstein; Malcolm A S Moore; K A Hajjar; Katia Manova-Todorova; Robert Benezra; Shahin Rafii
Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth.
Nature medicine 2001;7(11):1194-201.
2001: Michael Dans; Laurent Gagnoux-Palacios; Pamela Blaikie; Sharon Klein; Agnese Mariotti; Filippo G Giancotti
Tyrosine phosphorylation of the beta 4 integrin cytoplasmic domain mediates Shc signaling to extracellular signal-regulated kinase and antagonizes formation of hemidesmosomes.
The Journal of biological chemistry 2001;276(2):1494-502.
1998: Chiara Murgia; Pamela Blaikie; N Kim; Michael Dans; Howard T Petrie; Filippo G Giancotti
Cell cycle and adhesion defects in mice carrying a targeted deletion of the integrin beta4 cytoplasmic domain.
The EMBO journal 1998;17(14):3940-51.