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Ian Blair

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Rats

Physiology

Lipid Peroxidation

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Co-Publications
Name
29
Lee, Seon Hwa
19
Oe, Tomoyuki
12
Penning, Trevor
9
Felix, Carolyn
8
Chaudhary, AK
7
Williams, Michelle
6
Whitehead, Alexander
6
Belas, FJ
6
Harvey, Ronald
6
Jian, Wenying
6
Marnett, Lawrence
5
Arora, Jasbir
5
Christman, Brian
5
Yocum, Anastasia
5
Roberts, Jackson

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Publications

TOP 3
Rangiah Kannan; Tippornwong Montri; Sangar Vineet; Austin David; Tétreault Marie-Pier; Rustgi Anil K; Blair Ian A; Yu Kenneth H
Differential secreted proteome approach in murine model for candidate biomarker discovery in colon cancer.
Zhu Peijuan; Jian Wenying; Blair Ian A
A 4-oxo-2(E)-nonenal-derived glutathione adduct from 15-lipoxygenase-1-mediated oxidation of cytosolic and esterified arachidonic acid.
Wei Cong; Zhu Peijuan; Shah Sumit J; Blair Ian A
15-oxo-Eicosatetraenoic acid, a metabolite of macrophage 15-hydroxyprostaglandin dehydrogenase that inhibits endothelial cell proliferation.

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All Publications

2009: Rangiah Kannan; Tippornwong Montri; Sangar Vineet; Austin David; Tétreault Marie-Pier; Rustgi Anil K; Blair Ian A; Yu Kenneth H
Differential secreted proteome approach in murine model for candidate biomarker discovery in colon cancer.
Journal of proteome research 2009;8(11):5153-64.
2009: Zhu Peijuan; Jian Wenying; Blair Ian A
A 4-oxo-2(E)-nonenal-derived glutathione adduct from 15-lipoxygenase-1-mediated oxidation of cytosolic and esterified arachidonic acid.
Free radical biology & medicine 2009;47(7):953-61.
2009: Wei Cong; Zhu Peijuan; Shah Sumit J; Blair Ian A
15-oxo-Eicosatetraenoic acid, a metabolite of macrophage 15-hydroxyprostaglandin dehydrogenase that inhibits endothelial cell proliferation.
Molecular pharmacology 2009;76(3):516-25.
2009: Mesaros Clementina; Lee Seon Hwa; Blair Ian A
Targeted quantitative analysis of eicosanoid lipids in biological samples using liquid chromatography-tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2009;877(26):2736-45.
2009: Mitchell Laura E; Morales Megan; Khartulyari Stefanie; Huang Yuehua; Murphy Kristen; Mei Minghua; Von Feldt Joan M; Blair Ian A; Whitehead Alexander S
Folate and homocysteine phenotypes: Comparative findings using research and clinical laboratory data.
Clinical biochemistry 2009;42(12):1275-81.
2009: Lu Zhi-Yong; Jensen Liselotte E; Huang Yuehua; Kealey Carmel; Blair Ian A; Whitehead Alexander S
The up-regulation of monocyte chemoattractant protein-1 (MCP-1) in Ea.hy 926 endothelial cells under long-term low folate stress is mediated by the p38 MAPK pathway.
Atherosclerosis 2009;205(1):48-54.
2009: Jian Wenying; Lee Seon Hwa; Williams Michelle V; Blair Ian A
5-Lipoxygenase-mediated endogenous DNA damage.
The Journal of biological chemistry 2009;284(25):16799-807.
2009: Weibel Ginny L; Joshi Michelle R; Alexander Eric T; Zhu Peijuan; Blair Ian A; Rothblat George H
Overexpression of human 15(S)-lipoxygenase-1 in RAW macrophages leads to increased cholesterol mobilization and reverse cholesterol transport.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(6):837-42.
2009: Ciccimaro Eugene; Hanks Steven K; Yu Kenneth H; Blair Ian A
Absolute quantification of phosphorylation on the kinase activation loop of cellular focal adhesion kinase by stable isotope dilution liquid chromatography/mass spectrometry.
Analytical chemistry 2009;81(9):3304-13.
2009: Mangal Dipti; Vudathala Daljit; Park Jong-Heum; Lee Seon Hwa; Penning Trevor M; Blair Ian A
Analysis of 7,8-dihydro-8-oxo-2'-deoxyguanosine in cellular DNA during oxidative stress.
Chemical research in toxicology 2009;22(5):788-97.
2009: Shah Sumit J; Yu Kenneth H; Sangar Vineet; Parry Samuel I; Blair Ian A
Identification and quantification of preterm birth biomarkers in human cervicovaginal fluid by liquid chromatography/tandem mass spectrometry.
Journal of proteome research 2009;8(5):2407-17.
2009: Jin Yi; Duan Ling; Lee Seon Hwa; Kloosterboer Helenius J; Blair Ian A; Penning Trevor M
Human cytosolic hydroxysteroid dehydrogenases of the aldo-ketoreductase superfamily catalyze reduction of conjugated steroids: implications for phase I and phase II steroid hormone metabolism.
The Journal of biological chemistry 2009;284(15):10013-22.
2009: Yu Kenneth H; Barry Colin G; Austin David; Busch Christine M; Sangar Vineet; Rustgi Anil K; Blair Ian A
Stable isotope dilution multidimensional liquid chromatography-tandem mass spectrometry for pancreatic cancer serum biomarker discovery.
Journal of proteome research 2009;8(3):1565-76.
2009: Ciccimaro Eugene; Hanks Steven K; Blair Ian A
Quantification of focal adhesion kinase activation loop phosphorylation as a biomarker of Src activity.
Molecular pharmacology 2009;75(3):658-66.
2009: Yang In-Young; Hashimoto Keiji; de Wind Niels; Blair Ian A; Moriya Masaaki
Two distinct translesion synthesis pathways across a lipid peroxidation-derived DNA adduct in mammalian cells.
The Journal of biological chemistry 2009;284(1):191-8.
2009: Hahn Chang-Gyu; Banerjee Anamika; Macdonald Matthew L; Cho Dan-Sung; Kamins Joshua; Nie Zhiping; Borgmann-Winter Karin E; Grosser Tilo; Pizarro Angel; Ciccimaro Eugene; Arnold Steven E; Wang Hoau-Yan; Blair Ian A
The post-synaptic density of human postmortem brain tissues: an experimental study paradigm for neuropsychiatric illnesses.
PloS one 2009;4(4):e5251.
2008: Lu Zhi-Yong; Morales Megan; Khartulyari Stephanie; Mei Minghua; Murphy Kristen M; Stanislawska-Sachadyn Anna; Summers Carolyn M; Huang Yuehua; Von Feldt Joan M; Blair Ian A; Mitchell Laura E; Whitehead Alexander S
Genetic and biochemical determinants of serum concentrations of monocyte chemoattractant protein-1, a potential neural tube defect risk factor.
Birth defects research. Part A, Clinical and molecular teratology 2008;82(10):736-41.
2008: Huang Yuehua; Khartulyari Stefanie; Morales Megan E; Stanislawska-Sachadyn Anna; Von Feldt Joan M; Whitehead Alexander S; Blair Ian A
Quantification of key red blood cell folates from subjects with defined MTHFR 677C>T genotypes using stable isotope dilution liquid chromatography/mass spectrometry.
Rapid communications in mass spectrometry : RCM 2008;22(16):2403-12.
2008: Blair Ian A
DNA adducts with lipid peroxidation products.
The Journal of biological chemistry 2008;283(23):15545-9.
2008: Park Jong-Heum; Gelhaus Stacy; Vedantam Srilakshmi; Oliva Andrea L; Batra Abhita; Blair Ian A; Troxel Andrea B; Field Jeffrey; Penning Trevor M
The pattern of p53 mutations caused by PAH o-quinones is driven by 8-oxo-dGuo formation while the spectrum of mutations is determined by biological selection for dominance.
Chemical research in toxicology 2008;21(5):1039-49.
2008: Park Jong-Heum; Mangal Dipti; Tacka Kirk A; Quinn Amy M; Harvey Ronald G; Blair Ian A; Penning Trevor M
Evidence for the aldo-keto reductase pathway of polycyclic aromatic trans-dihydrodiol activation in human lung A549 cells.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(19):6846-51.
2008: Lucitt Margaret B; Price Thomas S; Pizarro Angel; Wu Weichen; Yocum Anastasia K; Seiler Christoph; Pack Michael A; Blair Ian A; Fitzgerald Garret A; Grosser Tilo
Analysis of the zebrafish proteome during embryonic development.
Molecular & cellular proteomics : MCP 2008;7(5):981-94.
2008: Shultz Carol A; Palackal Nisha T; Mangal Dipti; Harvey Ronald G; Blair Ian A; Penning Trevor M
Fjord-region benzo[g]chrysene-11,12-dihydrodiol and benzo[c]phenanthrene-3,4-dihydrodiol as substrates for rat liver dihydrodiol dehydrogenase (AKR1C9): structural basis for stereochemical preference.
Chemical research in toxicology 2008;21(3):668-77.
2008: Zhu Peijuan; Oe Tomoyuki; Blair Ian A
Determination of cellular redox status by stable isotope dilution liquid chromatography/mass spectrometry analysis of glutathione and glutathione disulfide.
Rapid communications in mass spectrometry : RCM 2008;22(4):432-40.
2007: Lee Seon Hwa; Rangiah Kannan; Williams Michelle V; Wehr Angela Y; DuBois Raymond N; Blair Ian A
Cyclooxygenase-2-mediated metabolism of arachidonic acid to 15-oxo-eicosatetraenoic acid by rat intestinal epithelial cells.
Chemical research in toxicology 2007;20(11):1665-75.
2007: Jiang Hao; Gelhaus Stacy L; Mangal Dipti; Harvey Ronald G; Blair Ian A; Penning Trevor M
Metabolism of benzo[a]pyrene in human bronchoalveolar H358 cells using liquid chromatography-mass spectrometry.
Chemical research in toxicology 2007;20(9):1331-41.
2007: Jian Wenying; Lee Seon Hwa; Mesaros Clementina; Oe Tomoyuki; Elipe Maria V Silva; Blair Ian A
A novel 4-oxo-2(E)-nonenal-derived endogenous thiadiazabicyclo glutathione adduct formed during cellular oxidative stress.
Chemical research in toxicology 2007;20(7):1008-18.
2007: Pettinella Caterina; Lee Seon Hwa; Cipollone Francesco; Blair Ian A
Targeted quantitative analysis of fatty acids in atherosclerotic plaques by high sensitivity liquid chromatography/tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2007;850(1-2):168-76.
2007: Ruan Qian; Gelhaus Stacy L; Penning Trevor M; Harvey Ronald G; Blair Ian A
Aldo-keto reductase- and cytochrome P450-dependent formation of benzo[a]pyrene-derived DNA adducts in human bronchoalveolar cells.
Chemical research in toxicology 2007;20(3):424-31.
2007: Price Thomas S; Lucitt Margaret B; Wu Weichen; Austin David J; Pizarro Angel; Yocum Anastasia K; Blair Ian A; FitzGerald Garret A; Grosser Tilo
EBP, a program for protein identification using multiple tandem mass spectrometry datasets.
Molecular & cellular proteomics : MCP 2007;6(3):527-36.
2007: Huang Yuehua; Lu Zhi-Yong; Brown Karen S; Whitehead Alexander S; Blair Ian A
Quantification of intracellular homocysteine by stable isotope dilution liquid chromatography/tandem mass spectrometry.
Biomedical chromatography : BMC 2007;21(1):107-12.
2007: Lee Seon Hwa; Blair Ian A
Targeted chiral lipidomics analysis by liquid chromatography electron capture atmospheric pressure chemical ionization mass spectrometry (LC-ECAPCI/MS).
Methods in enzymology 2007;433():159-74.
2006: Lee Seon Hwa; Pettinella Caterina; Blair Ian A
LC/ESI/MS analysis of saturated and unsaturated fatty acids in rat intestinal epithelial cells.
Current drug metabolism 2006;7(8):929-37.
2006: Zheng Naiyu; Pang Shaokun; Oe Tomoyuki; Felix Carolyn A; Wehrli Suzanne; Blair Ian A
Characterization of an etoposide-glutathione conjugate derived from metabolic activation by human cytochrome p450.
Current drug metabolism 2006;7(8):897-911.
2006: Blair Ian A
Endogenous glutathione adducts.
Current drug metabolism 2006;7(8):853-72.
2006: Brown Karen S; Huang Yuehua; Lu Zhi-Yong; Jian Wenying; Blair Ian A; Whitehead Alexander S
Mild folate deficiency induces a proatherosclerotic phenotype in endothelial cells.
Atherosclerosis 2006;189(1):133-41.
2006: Yocum Anastasia K; Busch Christine M; Felix Carolyn A; Blair Ian A
Proteomics-based strategy to identify biomarkers and pharmacological targets in leukemias with t(4;11) translocations.
Journal of proteome research 2006;5(10):2743-53.
2006: Pollack Michael; Yang In-Young; Kim Hye-Young H; Blair Ian A; Moriya Masaaki
Translesion DNA Synthesis across the heptanone--etheno-2'-deoxycytidine adduct in cells.
Chemical research in toxicology 2006;19(8):1074-9.
2006: Zhu Peijuan; Lee Seon Hwa; Wehrli Suzanne; Blair Ian A
Characterization of a lipid hydroperoxide-derived RNA adduct in rat intestinal epithelial cells.
Chemical research in toxicology 2006;19(6):809-17.
2006: Williams Michelle V; Lee Seon Hwa; Pollack Michael; Blair Ian A
Endogenous lipid hydroperoxide-mediated DNA-adduct formation in min mice.
The Journal of biological chemistry 2006;281(15):10127-33.
2006: Jiang Hao; Vudathala Daljit K; Blair Ian A; Penning Trevor M
Competing roles of aldo-keto reductase 1A1 and cytochrome P4501B1 in benzo[a]pyrene-7,8-diol activation in human bronchoalveolar H358 cells: role of AKRs in P4501B1 induction.
Chemical research in toxicology 2006;19(1):68-78.
2006: Oe Tomoyuki; Ackermann Bradley L; Inoue Koichi; Berna Michael J; Garner Carlos O; Gelfanova Valentina; Dean Robert A; Siemers Eric R; Holtzman David M; Farlow Martin R; Blair Ian A
Quantitative analysis of amyloid beta peptides in cerebrospinal fluid of Alzheimer's disease patients by immunoaffinity purification and stable isotope dilution liquid chromatography/negative electrospray ionization tandem mass spectrometry.
Rapid communications in mass spectrometry : RCM 2006;20(24):3723-35.
2006: Ciccimaro Eugene; Hevko John; Blair Ian A
Analysis of phosphorylation sites on focal adhesion kinase using nanospray liquid chromatography/multiple reaction monitoring mass spectrometry.
Rapid communications in mass spectrometry : RCM 2006;20(24):3681-92.
2006: Ruan Qian; Kim Hye-Young H; Jiang Hao; Penning Trevor M; Harvey Ronald G; Blair Ian A
Quantification of benzo[a]pyrene diol epoxide DNA-adducts by stable isotope dilution liquid chromatography/tandem mass spectrometry.
Rapid communications in mass spectrometry : RCM 2006;20(8):1369-80.
2006: Inoue Koichi; Garner Carlos; Ackermann Bradley L; Oe Tomoyuki; Blair Ian A
Liquid chromatography/tandem mass spectrometry characterization of oxidized amyloid beta peptides as potential biomarkers of Alzheimer's disease.
Rapid communications in mass spectrometry : RCM 2006;20(5):911-8.
2005: Yan Yuan; Weaver Valerie M; Blair Ian A
Analysis of protein expression during oxidative stress in breast epithelial cells using a stable isotope labeled proteome internal standard.
Journal of proteome research 2005;4(6):2007-14.
2005: Jian Wenying; Arora Jasbir S; Oe Tomoyuki; Shuvaev Vladimir V; Blair Ian A
Induction of endothelial cell apoptosis by lipid hydroperoxide-derived bifunctional electrophiles.
Free radical biology & medicine 2005;39(9):1162-76.
2005: Yu Kenneth H; Rustgi Anil K; Blair Ian A
Characterization of proteins in human pancreatic cancer serum using differential gel electrophoresis and tandem mass spectrometry.
Journal of proteome research 2005;4(5):1742-51.
2005: Yocum Anastasia K; Yu Kenneth; Oe Tomoyuki; Blair Ian A
Effect of immunoaffinity depletion of human serum during proteomic investigations.
Journal of proteome research 2005;4(5):1722-31.
2005: Lee Seon Hwa; Williams Michelle V; Blair Ian A
Targeted chiral lipidomics analysis.
Prostaglandins & other lipid mediators 2005;77(1-4):141-57.
2005: Lee Seon Hwa; Williams Michelle V; Dubois Raymond N; Blair Ian A
Cyclooxygenase-2-mediated DNA damage.
The Journal of biological chemistry 2005;280(31):28337-46.
2005: Yocum Anastasia K; Oe Tomoyuki; Yergey Alfred L; Blair Ian A
Novel lipid hydroperoxide-derived hemoglobin histidine adducts as biomarkers of oxidative stress.
Journal of mass spectrometry : JMS 2005;40(6):754-64.
2005: Lee Seon Hwa; Oe Tomoyuki; Arora Jasbir S; Blair Ian A
Analysis of FeII-mediated decomposition of a linoleic acid-derived lipid hydroperoxide by liquid chromatography/mass spectrometry.
Journal of mass spectrometry : JMS 2005;40(5):661-8.
2005: Lee Seon Hwa; Arora Jasbir A; Oe Tomoyuki; Blair Ian A
4-Hydroperoxy-2-nonenal-induced formation of 1,N2-etheno-2'-deoxyguanosine adducts.
Chemical research in toxicology 2005;18(4):780-6.
2005: Mistry Anita R; Felix Carolyn A; Whitmarsh Ryan J; Mason Annabel; Reiter Andreas; Cassinat Bruno; Parry Anne; Walz Christoph; Wiemels Joseph L; Segal Mark R; Adès Lionel; Blair Ian A; Osheroff Neil; Peniket Andrew J; Lafage-Pochitaloff Marina; Cross Nicholas C P; Chomienne Christine; Solomon Ellen; Fenaux Pierre; Grimwade David
DNA topoisomerase II in therapy-related acute promyelocytic leukemia.
The New England journal of medicine 2005;352(15):1529-38.
2005: Jian Wenying; Lee Seon Hwa; Arora Jasbir S; Silva Elipe Maria V; Blair Ian A
Unexpected formation of etheno-2'-deoxyguanosine adducts from 5(S)-hydroperoxyeicosatetraenoic acid: evidence for a bis-hydroperoxide intermediate.
Chemical research in toxicology 2005;18(3):599-610.
2005: Lee Seon Hwa; Silva Elipe Maria V; Arora Jasbir S; Blair Ian A
Dioxododecenoic acid: a lipid hydroperoxide-derived bifunctional electrophile responsible for etheno DNA adduct formation.
Chemical research in toxicology 2005;18(3):566-78.
2005: Szewczuk Lawrence M; Lee Seon Hwa; Blair Ian A; Penning Trevor M
Viniferin formation by COX-1: evidence for radical intermediates during co-oxidation of resveratrol.
Journal of natural products 2005;68(1):36-42.
2005: Williams Michelle V; Lee Seon Hwa; Blair Ian A
Liquid chromatography/mass spectrometry analysis of bifunctional electrophiles and DNA adducts from vitamin C mediated decomposition of 15-hydroperoxyeicosatetraenoic acid.
Rapid communications in mass spectrometry : RCM 2005;19(6):849-58.
2004: Zhuo Xiaoliang; Zheng Naiyu; Felix Carolyn A; Blair Ian A
Kinetics and regulation of cytochrome P450-mediated etoposide metabolism.
Drug metabolism and disposition: the biological fate of chemicals 2004;32(9):993-1000.
2004: Zheng Naiyu; Felix Carolyn A; Pang Shaokun; Boston Ray; Moate Peter; Scavuzzo Jennifer; Blair Ian A
Plasma etoposide catechol increases in pediatric patients undergoing multiple-day chemotherapy with etoposide.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(9):2977-85.
2003: Oe Tomoyuki; Lee Seon Hwa; Silva Elipe Maria V; Arison Byron H; Blair Ian A
A novel lipid hydroperoxide-derived modification to arginine.
Chemical research in toxicology 2003;16(12):1598-605.
2003: Whitmarsh Ryan J; Saginario Charles; Zhuo Ya; Hilgenfeld Eva; Rappaport Eric F; Megonigal Maureen D; Carroll Martin; Liu Mingli; Osheroff Neil; Cheung Nai-Kong V; Slater Diana J; Ried Thomas; Knutsen Turid; Blair Ian A; Felix Carolyn A
Reciprocal DNA topoisomerase II cleavage events at 5'-TATTA-3' sequences in MLL and AF-9 create homologous single-stranded overhangs that anneal to form der(11) and der(9) genomic breakpoint junctions in treatment-related AML without further processing.
Oncogene 2003;22(52):8448-59.
2003: Oe Tomoyuki; Arora Jasbir S; Lee Seon Hwa; Blair Ian A
A novel lipid hydroperoxide-derived cyclic covalent modification to histone H4.
The Journal of biological chemistry 2003;278(43):42098-105.
2003: Pollack Michael; Oe Tomoyuki; Lee Seon Hwa; Silva Elipe Maria Victoria; Arison Byron H; Blair Ian A
Characterization of 2'-deoxycytidine adducts derived from 4-oxo-2-nonenal, a novel lipid peroxidation product.
Chemical research in toxicology 2003;16(7):893-900.
2003: Oe Tomoyuki; Tian Ye; O'Dwyer Peter J; Roberts David W; Bailey Christopher J; Blair Ian A
Determination of the platinum drug cis-amminedichloro(2-methylpyridine)platinum(II) in human urine by liquid chromatography-tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2003;792(2):217-27.
2003: Bauer Todd W; Gutierrez Marcos; Dudrick Daniel J; Li Jiarong; Blair Ian A; Menon Chandrakala; Fraker Douglas L
A human melanoma xenograft in a nude rat responds to isolated limb perfusion with TNF plus melphalan.
Surgery 2003;133(4):420-8.
2003: Lee Seon Hwa; Williams Michelle V; DuBois Raymond N; Blair Ian A
Targeted lipidomics using electron capture atmospheric pressure chemical ionization mass spectrometry.
Rapid communications in mass spectrometry : RCM 2003;17(19):2168-76.
2002: Blair Ian A; Tilve Anita
Analysis of anticancer drugs and their metabolites by mass spectrometry.
Current drug metabolism 2002;3(5):463-80.
2002: Palackal Nisha T; Lee Seon Hwa; Harvey Ronald G; Blair Ian A; Penning Trevor M
Activation of polycyclic aromatic hydrocarbon trans-dihydrodiol proximate carcinogens by human aldo-keto reductase (AKR1C) enzymes and their functional overexpression in human lung carcinoma (A549) cells.
The Journal of biological chemistry 2002;277(27):24799-808.
2002: Lee Seon Hwa; Oe Tomoyuki; Blair Ian A
4,5-Epoxy-2(E)-decenal-induced formation of 1,N(6)-etheno-2'-deoxyadenosine and 1,N(2)-etheno-2'-deoxyguanosine adducts.
Chemical research in toxicology 2002;15(3):300-4.
2002: Oe Tomoyuki; Tian Ye; O'Dwyer Peter J; Roberts David W; Malone Michael D; Bailey Christopher J; Blair Ian A
A validated liquid chromatography/tandem mass spectrometry assay for cis-amminedichloro(2-methylpyridine)platinum(II) in human plasma ultrafiltrate.
Analytical chemistry 2002;74(3):591-9.
2001: Blair I A
Lipid hydroperoxide-mediated DNA damage.
Experimental gerontology 2001;36(9):1473-81.
2001: Lovett B D; Lo Nigro L; Rappaport E F; Blair I A; Osheroff N; Zheng N; Megonigal M D; Williams W R; Nowell P C; Felix C A
Near-precise interchromosomal recombination and functional DNA topoisomerase II cleavage sites at MLL and AF-4 genomic breakpoints in treatment-related acute lymphoblastic leukemia with t(4;11) translocation.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(17):9802-7.
2001: Pang S; Zheng N; Felix C A; Scavuzzo J; Boston R; Blair I A
Simultaneous determination of etoposide and its catechol metabolite in the plasma of pediatric patients by liquid chromatography/tandem mass spectrometry.
Journal of mass spectrometry : JMS 2001;36(7):771-81.
2001: Lee S H; Oe T; Blair I A
Vitamin C-induced decomposition of lipid hydroperoxides to endogenous genotoxins.
Science (New York, N.Y.) 2001;292(5524):2083-6.
2001: Lee S H; Blair I A
Oxidative DNA damage and cardiovascular disease.
Trends in cardiovascular medicine 2001;11(3-4):148-55.
2001: Lovett B D; Strumberg D; Blair I A; Pang S; Burden D A; Megonigal M D; Rappaport E F; Rebbeck T R; Osheroff N; Pommier Y G; Felix C A
Etoposide metabolites enhance DNA topoisomerase II cleavage near leukemia-associated MLL translocation breakpoints.
Biochemistry 2001;40(5):1159-70.
2000: Rindgen D; Lee S H; Nakajima M; Blair I A
Formation of a substituted 1,N(6)-etheno-2'-deoxyadenosine adduct by lipid hydroperoxide-mediated generation of 4-oxo-2-nonenal.
Chemical research in toxicology 2000;13(9):846-52.
2000: Ning C; Fenn P T; Blair I A; Berry G T; Segal S
Apparent galactose appearance rate in human galactosemia based on plasma [(13)C]galactose isotopic enrichment.
Molecular genetics and metabolism 2000;70(4):261-71.
2000: Lee S H; Blair I A
Characterization of 4-oxo-2-nonenal as a novel product of lipid peroxidation.
Chemical research in toxicology 2000;13(8):698-702.
2000: Singh G; Gutierrez A; Xu K; Blair I A
Liquid chromatography/electron capture atmospheric pressure chemical ionization/mass spectrometry: analysis of pentafluorobenzyl derivatives of biomolecules and drugs in the attomole range.
Analytical chemistry 2000;72(14):3007-13.
2000: Lee S H; Rindgen D; Bible R H; Hajdu E; Blair I A
Characterization of 2'-deoxyadenosine adducts derived from 4-oxo-2-nonenal, a novel product of lipid peroxidation.
Chemical research in toxicology 2000;13(7):565-74.
2000: Xu K; Lanuti M; Lambright E S; Force S D; Albelda S M; Blair I A
A rapid and sensitive method for the quantification of ganciclovir in plasma using liquid chromatography/selected reaction monitoring/mass spectrometry.
Biomedical chromatography : BMC 2000;14(2):93-8.
2000: Blair I A; Oe T; Kambouris S; Chaudhary A K
1,3-butadiene: cancer, mutations, and adducts. Part IV: Molecular dosimetry of 1,3-butadiene.
Research report (Health Effects Institute) 2000;(92):151-90; discussion 211-9.
2000: Zhang J Y; Fast D M; Schoenhard G L; Arora V K; Belas F J; Blair I A
Quantitative determination of SC-68328 in dog plasma using flow injection and tandem mass spectrometry.
Journal of mass spectrometry : JMS 2000;35(3):354-60.
2000: Fenn P T; Ning C; Segal S; Blair I A
Determination of [(13)C]galactose enrichment in human plasma by gas chromatography/positive chemical ionization tandem mass spectrometry.
Journal of mass spectrometry : JMS 2000;35(2):218-23.
1999: Rindgen D; Nakajima M; Wehrli S; Xu K; Blair I A
Covalent modifications to 2'-deoxyguanosine by 4-oxo-2-nonenal, a novel product of lipid peroxidation.
Chemical research in toxicology 1999;12(12):1195-204.
1999: Xu K; Arora V K; Chaudhary A K; Cotton R B; Blair I A
Quantitative analysis of cimetidine in human plasma using LC/APCI/SRM/MS.
Biomedical chromatography : BMC 1999;13(7):455-61.
1999: Singh G; Arora V; Fenn P T; Mets B; Blair I A
A validated stable isotope dilution liquid chromatography tandem mass spectrometry assay for the trace analysis of cocaine and its major metabolites in plasma.
Analytical chemistry 1999;71(10):2021-7.
1999: Oe T; Kambouris S J; Walker V E; Meng Q; Recio L; Wherli S; Chaudhary A K; Blair I A
Persistence of N7-(2,3,4-trihydroxybutyl)guanine adducts in the livers of mice and rats exposed to 1,3-butadiene.
Chemical research in toxicology 1999;12(3):247-57.
1999: McCoull K D; Rindgen D; Blair I A; Penning T M
Synthesis and characterization of polycyclic aromatic hydrocarbon o-quinone depurinating N7-guanine adducts.
Chemical research in toxicology 1999;12(3):237-46.
1998: Felix C A; Walker A H; Lange B J; Williams T M; Winick N J; Cheung N K; Lovett B D; Nowell P C; Blair I A; Rebbeck T R
Association of CYP3A4 genotype with treatment-related leukemia.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(22):13176-81.
1997: Lang C C; Stein C M; Nelson R A; He H B; Belas F J; Blair I A; Wood M; Wood A J
Sympathoinhibitory response to clonidine is blunted in patients with heart failure.
Hypertension 1997;30(3 Pt 1):392-7.
1997: Lang C C; Stein C M; He H B; Belas F J; Blair I A; Wood M; Wood A J
Blunted blood pressure response to central sympathoinhibition in normotensive blacks: increased importance of nonsympathetic factors in blood pressure maintenance in blacks.
Hypertension 1997;30(2 Pt 1):157-62.
1997: Müller M; Belas F J; Blair I A; Guengerich F P
Analysis of 1,N2-ethenoguanine and 5,6,7,9-tetrahydro-7-hydroxy-9-oxoimidazo[1,2-a]purine in DNA treated with 2-chlorooxirane by high performance liquid chromatography/electrospray mass spectrometry and comparison of amounts to other DNA adducts.
Chemical research in toxicology 1997;10(2):242-7.
1997: Rouzer C A; Chaudhary A K; Nokubo M; Ferguson D M; Reddy G R; Blair I A; Marnett L J
Analysis of the malondialdehyde-2'-deoxyguanosine adduct pyrimidopurinone in human leukocyte DNA by gas chromatography/electron capture/negative chemical ionization/mass spectrometry.
Chemical research in toxicology 1997;10(2):181-8.
1996: Kambouris S J; Chaudhary A K; Blair I A
Liquid chromatography/electrospray ionization tandem mass spectroscopy (LC/ESI MS/MS) analysis of 1,2-epoxybutene adducts of purine deoxynucleosides.
Toxicology 1996;113(1-3):331-5.
1996: Goldthwaite C A; Hsieh F Y; Womble S W; Nobes B J; Blair I A; Klunk L J; Mayol R F
Liquid chromatography/chemical reaction interface mass spectrometry as an alternative to radioisotopes for quantitative drug metabolism studies.
Analytical chemistry 1996;68(17):2996-3001.
1996: Chaudhary A K; Reddy G R; Blair I A; Marnett L J
Characterization of an N6-oxopropenyl-2'-deoxyadenosine adduct in malondialdehyde-modified DNA using liquid chromatography/electrospray ionization tandem mass spectrometry.
Carcinogenesis 1996;17(5):1167-70.
1996: Srinivas N R; Barr W H; Shyu W C; Mohandoss E; Chow S; Staggers J; Balan G; Belas F J; Blair I A; Barbhaiya R H
Bioequivalence of two tablet formulations of nadolol using single and multiple dose data: assessment using stereospecific and nonstereospecific assays.
Journal of pharmaceutical sciences 1996;85(3):299-303.
1995: Brash A R; Boeglin W E; Capdevila J H; Yeola S; Blair I A
7-HETE, 10-HETE, and 13-HETE are major products of NADPH-dependent arachidonic acid metabolism in rat liver microsomes: analysis of their stereochemistry, and the stereochemistry of their acid-catalyzed rearrangement.
Archives of biochemistry and biophysics 1995;321(2):485-92.
1995: Belas F J; Phillips M A; Srinivas N R; Barbhaiya R H; Blair I A
Simultaneous determination of nadolol enantiomers in human plasma by high-performance liquid chromatography using fluorescence detection.
Biomedical chromatography : BMC 1995;9(3):140-5.
1994: Beckman J K; Bagheri F; Ji C; Blair I A; Marnett L J
Phospholipid peroxidation in tumor promoter-exposed mouse skin.
Carcinogenesis 1994;15(12):2937-44.
1994: Blair I A; Dougherty R M; Iacono J M
Dietary stearic acid and thromboxane-prostacyclin biosynthesis in normal human subjects.
The American journal of clinical nutrition 1994;60(6 Suppl):1054S-1058S.
1994: Chaudhary A K; Nokubo M; Reddy G R; Yeola S N; Morrow J D; Blair I A; Marnett L J
Detection of endogenous malondialdehyde-deoxyguanosine adducts in human liver.
Science (New York, N.Y.) 1994;265(5178):1580-2.
1994: Prakash C; Nelson G J; Wu M M; Schmidt P C; Phillips M A; Blair I A
Decreased systemic thromboxane A2 biosynthesis in normal human subjects fed a salmon-rich diet.
The American journal of clinical nutrition 1994;60(3):369-73.
1994: Chaudhary A K; Nokubo M; Marnett L J; Blair I A
Analysis of the malondialdehyde-2'-deoxyguanosine adduct in rat liver DNA by gas chromatography/electron capture negative chemical ionization mass spectrometry.
Biological mass spectrometry 1994;23(8):457-64.
1994: Zhang J Y; Nobes B J; Wang J; Blair I A
Characterization of hydroxyeicosatetraenoic acids and hydroxyeicosatetraenoic acid phosphatidylcholines by liquid secondary ion tandem mass spectrometry.
Biological mass spectrometry 1994;23(7):399-405.
1994: Zhang J Y; Blair I A
Direct resolution of epoxyeicosatrienoic acid enantiomers by chiral-phase high-performance liquid chromatography.
Journal of chromatography. B, Biomedical applications 1994;657(1):23-9.
1994: Tamura M; Harris T M; Phillips D; Blair I A; Wang Y F; Hellerqvist C G; Lam S K; Inagami T
Identification of two cardiac glycosides as Na(+)-pump inhibitors in rat urine and diet.
The Journal of biological chemistry 1994;269(16):11972-9.
1994: Morrow J D; Minton T A; Mukundan C R; Campbell M D; Zackert W E; Daniel V C; Badr K F; Blair I A; Roberts L J
Free radical-induced generation of isoprostanes in vivo. Evidence for the formation of D-ring and E-ring isoprostanes.
The Journal of biological chemistry 1994;269(6):4317-26.
1994: Adedoyin A; Prakash C; O'Shea D; Blair I A; Wilkinson G R
Stereoselective disposition of hexobarbital and its metabolites: relationship to the S-mephenytoin polymorphism in Caucasian and Chinese subjects.
Pharmacogenetics 1994;4(1):27-38.
1993: Blair I A
Applications of mass spectrometry to toxicology.
Chemical research in toxicology 1993;6(6):741-7.
1993: Christman B W; Christman J W; Dworski R; Blair I A; Prakash C
Prostaglandin E2 limits arachidonic acid availability and inhibits leukotriene B4 synthesis in rat alveolar macrophages by a nonphospholipase A2 mechanism.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(4):2096-104.
1993: Homma T; Zhang J Y; Shimizu T; Prakash C; Blair I A; Harris R C
Cyclooxygenase-derived metabolites of 8,9-epoxyeicosatrienoic acid are potent mitogens for cultured rat glomerular mesangial cells.
Biochemical and biophysical research communications 1993;191(1):282-8.
1993: Blair I A; Prakash C; Phillips M A; Dougherty R M; Iacono J M
Dietary modification of omega 6 fatty acid intake and its effect on urinary eicosanoid excretion.
The American journal of clinical nutrition 1993;57(2):154-60.
1992: Jajoo H K; Burcham P C; Goda Y; Blair I A; Marnett L J
A thermospray liquid chromatography/mass spectrometry method for analysis of human urine for the major malondialdehyde-guanine adduct.
Chemical research in toxicology 1992;5(6):870-5.
1992: Morrow J D; Awad J A; Boss H J; Blair I A; Roberts L J
Non-cyclooxygenase-derived prostanoids (F2-isoprostanes) are formed in situ on phospholipids.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(22):10721-5.
1992: Wilson A L; Womble S W; Prakash C; Cragoe E J; Blair I A; Limbird L E
Novel amiloride analog allosterically modulates the alpha 2-adrenergic receptor but does not inhibit Na+/H+ exchange.
Molecular pharmacology 1992;42(2):175-9.
1992: Prakash C; Zhang J Y; Falck J R; Chauhan K; Blair I A
20-Hydroxyeicosatetraenoic acid is excreted as a glucuronide conjugate in human urine.
Biochemical and biophysical research communications 1992;185(2):728-33.
1992: Edeki T; Robin D W; Prakash C; Blair I A; Wood A J
Sensitive assay for triazolam in plasma following low oral doses.
Journal of chromatography 1992;577(1):190-4.
1992: Zhang J Y; Prakash C; Yamashita K; Blair I A
Regiospecific and enantioselective metabolism of 8,9-epoxyeicosatrienoic acid by cyclooxygenase.
Biochemical and biophysical research communications 1992;183(1):138-43.
1992: Jajoo H K; Capdevila J H; Falck J R; Bhatt R K; Blair I A
Metabolism of 12(R)-hydroxyeicosatetraenoic acid by rat liver microsomes.
Biochimica et biophysica acta 1992;1123(1):110-6.
1991: Prakash C; Adedoyin A; Wilkinson G R; Blair I A
Enantiospecific quantification of hexobarbital and its metabolites in biological fluids by gas chromatography/electron capture negative ion chemical ionization mass spectrometry.
Biological mass spectrometry 1991;20(9):559-64.
1991: Christman B W; Gay J C; Christman J W; Prakash C; Blair I A
Analysis of effector cell-derived lyso platelet activating factor by electron capture negative ion mass spectrometry.
Biological mass spectrometry 1991;20(9):545-52.
1991: Turgeon J; Funck-Brentano C; Gray H T; Pavlou H N; Prakash C; Blair I A; Roden D M
Genetically determined stereoselective excretion of encainide in humans and electrophysiologic effects of its enantiomers in canine cardiac Purkinje fibers.
Clinical pharmacology and therapeutics 1991;49(5):488-96.
1991: Ghabrial H; Prakash C; Tacke U G; Blair I A; Wilkinson G R
Geometric isomerization of doxepin during its N-demethylation in humans.
Drug metabolism and disposition: the biological fate of chemicals 1991;19(3):596-9.
1991: Legrand A B; Lawson J A; Meyrick B O; Blair I A; Oates J A
Substitution of 15-hydroxyeicosatetraenoic acid in the phosphoinositide signaling pathway.
The Journal of biological chemistry 1991;266(12):7570-7.
1991: Mayol R F; Jajoo H K; Klunk L J; Blair I A
Metabolism of the antipsychotic drug tiospirone in humans.
Drug metabolism and disposition: the biological fate of chemicals 1991;19(2):394-9.
1991: Morrow J D; Prakash C; Awad J A; Duckworth T A; Zackert W E; Blair I A; Oates J A; Roberts L J
Quantification of the major urinary metabolite of prostaglandin D2 by a stable isotope dilution mass spectrometric assay.
Analytical biochemistry 1991;193(1):142-8.
1991: Morrow J D; Prakash C; Duckworth T A; Zackert W E; Blair I A; Oates J A; Roberts L J
A stable isotope dilution mass spectrometric assay for the major urinary metabolite of PGD2.
Advances in prostaglandin, thromboxane, and leukotriene research 1991;21A():315-8.
1990: Christman B W; Lefferts P L; Blair I A; Snapper J R
Effect of platelet-activating factor receptor antagonism on endotoxin-induced lung dysfunction in awake sheep.
The American review of respiratory disease 1990;142(6 Pt 1):1272-8.
1990: Jajoo H K; Blair I A; Klunk L J; Mayol R F
In vitro metabolism of the antianxiety drug buspirone as a predictor of its metabolism in vivo.
Xenobiotica; the fate of foreign compounds in biological systems 1990;20(8):779-86.
1990: Jajoo H K; Prakash C; Mayol R F; Blair I A
Enantioselective metabolism of encainide by rat liver microsomes.
Biochemical pharmacology 1990;40(4):893-5.
1990: Jajoo H K; Blair I A; Klunk L J; Mayol R F
Characterization of in vitro metabolites of the antipsychotic drug tiospirone by mass spectrometry.
Biomedical & environmental mass spectrometry 1990;19(5):281-5.
1990: Turgeon J; Kroemer H K; Prakash C; Blair I A; Roden D M
Stereoselective determination of flecainide in human plasma by high-performance liquid chromatography with fluorescence detection.
Journal of pharmaceutical sciences 1990;79(2):91-5.
1990: Jajoo H K; Mayol R F; LaBudde J A; Blair I A
Structural characterization of urinary metabolites of the antiarrhythmic drug encainide in human subjects.
Drug metabolism and disposition: the biological fate of chemicals 1990;18(1):28-35.
1989: Hammonds T D; Blair I A; Falck J R; Capdevila J H
Resolution of epoxyeicosatrienoate enantiomers by chiral phase chromatography.
Analytical biochemistry 1989;182(2):300-3.
1989: Jajoo H K; Mayol R F; LaBudde J A; Blair I A
Metabolism of the antianxiety drug buspirone in human subjects.
Drug metabolism and disposition: the biological fate of chemicals 1989;17(6):634-40.
1989: Jajoo H K; Mayol R F; LaBudde J A; Blair I A
Metabolism of the antianxiety drug buspirone in the rat.
Drug metabolism and disposition: the biological fate of chemicals 1989;17(6):625-33.
1989: Prakash C; Saleh S; Taber D F; Blair I A
Synthesis of trideuterated O-alkyl platelet activating factor and lyso derivatives.
Lipids 1989;24(9):786-92.
1989: Prakash C; Koshakji R P; Wood A J; Blair I A
Simultaneous determination of propranolol enantiomers in plasma by high-performance liquid chromatography with fluorescence detection.
Journal of pharmaceutical sciences 1989;78(9):771-5.
1989: Prakash C; Jajoo H K; Blair I A; Mayol R F
Resolution of enantiomers of the antiarrhythmic drug encainide and its major metabolites by chiral derivatization and high-performance liquid chromatography.
Journal of chromatography 1989;493(2):325-35.
1989: Christman B W; Blair I A
Analysis of platelet activating factor in human saliva by gas chromatography/mass spectrometry.
Biomedical & environmental mass spectrometry 1989;18(4):258-64.
1989: Schaefer W H; Kakkad B; Crow J A; Blair I A; Ong D E
Purification, primary structure characterization, and cellular distribution of two forms of cellular retinol-binding protein, type II from adult rat small intestine.
The Journal of biological chemistry 1989;264(7):4212-21.
1989: Prakash C; Sweetman B J; Sivakumar R; Taffer I M; Zipkin R E; Blair I A
Preparation of omega trideuterated sulfidopeptide leukotrienes: analysis by FAB/MS.
Prostaglandins 1989;37(2):251-8.
1988: Sweetman B J; Blair I A
3-Nitrobenzyl alcohol has wide applicability as a matrix for FAB-MS.
Biomedical & environmental mass spectrometry 1988;17(4):337-40.
1988: Coggeshall J W; Christman B W; Lefferts P L; Serafin W E; Blair I A; Butterfield M J; Snapper J R
Effect of inhibition of 5-lipoxygenase metabolism of arachidonic acid on response to endotoxemia in sheep.
Journal of applied physiology (Bethesda, Md. : 1985) 1988;65(3):1351-9.
1988: Thompson K A; Murray J J; Blair I A; Woosley R L; Roden D M
Plasma concentrations of quinidine, its major metabolites, and dihydroquinidine in patients with torsades de pointes.
Clinical pharmacology and therapeutics 1988;43(6):636-42.
1987: Sweatt J D; Schwartzberg M S; Frazer M; Cragoe E J; Blair I A; Reed P W; Limbird L E
Evidence for a role for Na+-H+ exchange in activation of human platelets by PAF.
Circulation research 1987;61(5 Pt 2):II6-11.
1987: Prakash C; Roberts L J; Saleh S; Taber D F; Blair I A
Synthesis of putative prostaglandin D2 metabolites.
Advances in prostaglandin, thromboxane, and leukotriene research 1987;17B():781-7.

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