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Günter Schneider

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Laura Conradt; Annika Henrich; Oliver H Krämer; Marina Lesina; Maximilian Reichert; Dieter Saur; Roland M Schmid; Hana Algül; Matthias Wirth; Günter Schneider
Mdm2 inhibitors synergize with topoisomerase II inhibitors to induce p53-independent pancreatic cancer cell death.
Stefan Eser; Irene Esposito; Kathleen Gottschalk; Maren Hieber; Alexander J Kind; Sabine Klein; Bo Kong; Marlena Messer; Christoph W Michalski; Lena Rad; Roland Rad; Nina Reiff; Dario R Alessi; Andreas Arbeiter; Manuela Baccarini; Melanie Dobler; Anna Melissa Schlitter; Roland M Schmid; Günter Schneider; Angelika Schnieke; Barbara Seidler; Dieter Saur
Selective requirement of PI3K/PDK1 signaling for Kras oncogene-driven pancreatic cell plasticity and cancer.
Sandra Diersch; Philipp Eser; Stefan Eser; Irene Esposito; Marlena Messer; Philipp Pagel; Mariel C Paul; Maximilian Reichert; Dieter Saur; Roland M Schmid; Barbara Seidler; Melanie Szameitat; Patrick Wenzel; Günter Schneider
Efemp1 and p27(Kip1) modulate responsiveness of pancreatic cancer cells towards a dual PI3K/mTOR inhibitor in preclinical models.

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All Publications

2013: Laura Conradt; Annika Henrich; Oliver H Krämer; Marina Lesina; Maximilian Reichert; Dieter Saur; Roland M Schmid; Hana Algül; Matthias Wirth; Günter Schneider
Mdm2 inhibitors synergize with topoisomerase II inhibitors to induce p53-independent pancreatic cancer cell death.
International journal of cancer. Journal international du cancer 2013;132(10):2248-57.
2013: Stefan Eser; Irene Esposito; Kathleen Gottschalk; Maren Hieber; Alexander J Kind; Sabine Klein; Bo Kong; Marlena Messer; Christoph W Michalski; Lena Rad; Roland Rad; Nina Reiff; Dario R Alessi; Andreas Arbeiter; Manuela Baccarini; Melanie Dobler; Anna Melissa Schlitter; Roland M Schmid; Günter Schneider; Angelika Schnieke; Barbara Seidler; Dieter Saur
Selective requirement of PI3K/PDK1 signaling for Kras oncogene-driven pancreatic cell plasticity and cancer.
Cancer cell 2013;23(3):406-20.
2013: Sandra Diersch; Philipp Eser; Stefan Eser; Irene Esposito; Marlena Messer; Philipp Pagel; Mariel C Paul; Maximilian Reichert; Dieter Saur; Roland M Schmid; Barbara Seidler; Melanie Szameitat; Patrick Wenzel; Günter Schneider
Efemp1 and p27(Kip1) modulate responsiveness of pancreatic cancer cells towards a dual PI3K/mTOR inhibitor in preclinical models.
Oncotarget 2013;4(2):277-88.
2013: Sabine Klein; Roland Rad; Michael Rohn; Hans-Dieter Allescher; Robert Feil; Franz Hofmann; Anna Kettenberger; Michael Schemann; Roland M Schmid; Günter Schneider; Barbara Seidler; Andrei Sibaev; Martin Storr; Jean-Marie Vanderwinden; Dieter Saur
Interstitial cells of Cajal integrate excitatory and inhibitory neurotransmission with intestinal slow-wave activity.
Nature communications 2013;4():1630.
2012: Tatiana Flisikowska; Barbara Kessler; Alexander Kind; Mayuko Kurome; Martina Landmann; Claudia Merkl; Nousin Rezaei; Oswald Rottmann; Dieter Saur; Roland M Schmid; Günter Schneider; Xinxin Cui; Stefan Eser; Hagen Wieland; Eckhard Wolf; Valeri Zakhartchenko; Angelika Schnieke
A porcine model of familial adenomatous polyposis.
Gastroenterology 2012;143(5):1173-5.e1-7.
2012: Alexander von Werder; Roland M Schmid; Günter Schneider; Barbara Seidler; Dieter Saur
Production of avian retroviruses and tissue-specific somatic retroviral gene transfer in vivo using the RCAS/TVA system.
Nature protocols 2012;7(6):1167-83.
2012: Wajana L Labisso; Dieter Saur; Roland M Schmid; Angelika Schnieke; Roland H Stauber; Natasa Stojanovic; Matthias Wirth; Oliver H Krämer; Günter Schneider
MYC directs transcription of MCL1 and eIF4E genes to control sensitivity of gastric cancer cells toward HDAC inhibitors.
Cell cycle (Georgetown, Tex.) 2012;11(8):1593-602.
2012: Günter Schneider; Oliver H Krämer; Dieter Saur
A ZEB1-HDAC pathway enters the epithelial to mesenchymal transition world in pancreatic cancer.
Gut 2012;61(3):329-30.
2011: Alexander von Werder; Hans-Dieter Allescher; Ralph Fritsch; Franz Hofmann; Martina Mayr; Daniela Oesterle; Michael Schemann; Jens Schlossmann; Roland M Schmid; Günter Schneider; Barbara Seidler; Dieter Saur
Truncated IRAG variants modulate cGMP-mediated inhibition of human colonic smooth muscle cell contraction.
American journal of physiology. Cell physiology 2011;301(6):C1445-57.
2011: Laura Conradt; Sandra Diersch; Stefan Eser; Klaus Godl; Jörg Kleeff; Christoph W Michalski; Dieter Saur; Christoph Schaab; Roland M Schmid; Angelika Schnieke; Andreas Tebbe; Günter Schneider
Disclosure of erlotinib as a multikinase inhibitor in pancreatic ductal adenocarcinoma.
Neoplasia (New York, N.Y.) 2011;13(11):1026-34.
2011: Stefan Eser; Irene Esposito; Alexander Meining; Marlena Messer; Philipp Pagel; Roland M Schmid; Günter Schneider; Angelika Schnieke; Barbara Seidler; Roger Vogelmann; Johannes von Burstin; Alexander von Werder; Hana Algül; Monther Bajbouj; Philipp Eser; Dieter Saur
In vivo diagnosis of murine pancreatic intraepithelial neoplasia and early-stage pancreatic cancer by molecular imaging.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(24):9945-50.
2011: Günter Schneider; Oliver H Krämer; Roland M Schmid; Dieter Saur
Acetylation as a transcriptional control mechanism-HDACs and HATs in pancreatic ductal adenocarcinoma.
Journal of gastrointestinal cancer 2011;42(2):85-92.
2011: Günter Schneider; Dieter Saur
Mesenchymal stem cells: therapeutic potential for acute pancreatitis.
Gastroenterology 2011;140(3):779-82.
2011: Susanne Schüler; Sandra Diersch; Rainer Hamacher; Roland M Schmid; Dieter Saur; Günter Schneider
SKP2 confers resistance of pancreatic cancer cells towards TRAIL-induced apoptosis.
International journal of oncology 2011;38(1):219-25.
2011: Günter Schneider; Oliver H Krämer
NFκB/p53 crosstalk-a promising new therapeutic target.
Biochimica et biophysica acta 2011;1815(1):90-103.
2011: Matthias Wirth; Petra Fritsche; Natasa Stojanovic; Martina Brandl; Stephanie Jaeckel; Roland M Schmid; Dieter Saur; Günter Schneider
A simple and cost-effective method to transfect small interfering RNAs into pancreatic cancer cell lines using polyethylenimine.
Pancreas 2011;40(1):144-50.
2010: Martina Brandl; Barbara Seidler; Ferdinand Haller; Jerzy Adamski; Roland M Schmid; Dieter Saur; Günter Schneider
IKK(α) controls canonical TGF(ß)-SMAD signaling to regulate genes expressing SNAIL and SLUG during EMT in panc1 cells.
Journal of cell science 2010;123(Pt 24):4231-9.
2010: Melanie Scheibel; Bettina Klein; Heidrun Merkle; Manon Schulz; Ralph Fritsch; Florian R Greten; Melek C Arkan; Günter Schneider; Roland M Schmid
IkappaBbeta is an essential co-activator for LPS-induced IL-1beta transcription in vivo.
The Journal of experimental medicine 2010;207(12):2621-30.
2010: Günter Schneider; Oliver H Krämer; Petra Fritsche; Susanne Schüler; Roland M Schmid; Dieter Saur
Targeting histone deacetylases in pancreatic ductal adenocarcinoma.
Journal of cellular and molecular medicine 2010;14(6A):1255-63.
2010: Sabrina Marozin; Enrico N De Toni; Antonia Rizzani; Jennifer Altomonte; Alexandra Junger; Günter Schneider; Wolfgang E Thasler; Nobuyuki Kato; Roland M Schmid; Oliver Ebert
Cell cycle progression or translation control is not essential for vesicular stomatitis virus oncolysis of hepatocellular carcinoma.
PloS one 2010;5(6):e10988.
2010: Susanne Schüler; Petra Fritsche; Sandra Diersch; Alexander Arlt; Roland M Schmid; Dieter Saur; Günter Schneider
HDAC2 attenuates TRAIL-induced apoptosis of pancreatic cancer cells.
Molecular cancer 2010;9():80.
2009: Carolin Schild; Matthias Wirth; Maximilian Reichert; Roland M Schmid; Dieter Saur; Günter Schneider
PI3K signaling maintains c-myc expression to regulate transcription of E2F1 in pancreatic cancer cells.
Molecular carcinogenesis 2009;48(12):1149-58.
2009: Florian Nagl; Katrin Schönhofer; Barbara Seidler; Jörg Mages; Hans-Dieter Allescher; Roland M Schmid; Günter Schneider; Dieter Saur
Retinoic acid-induced nNOS expression depends on a novel PI3K/Akt/DAX1 pathway in human TGW-nu-I neuroblastoma cells.
American journal of physiology. Cell physiology 2009;297(5):C1146-56.
2009: P Fritsche; Barbara Seidler; S Schüler; Angelika Schnieke; M Göttlicher; Roland M Schmid; Dieter Saur; Günter Schneider
HDAC2 mediates therapeutic resistance of pancreatic cancer cells via the BH3-only protein NOXA.
Gut 2009;58(10):1399-409.
2009: Johannes von Burstin; Stefan Eser; Mariel C Paul; Barbara Seidler; Martina Brandl; Marlena Messer; Alexander von Werder; Annegret Schmidt; Jörg Mages; Philipp Pagel; Angelika Schnieke; Roland M Schmid; Günter Schneider; Dieter Saur
E-cadherin regulates metastasis of pancreatic cancer in vivo and is suppressed by a SNAIL/HDAC1/HDAC2 repressor complex.
Gastroenterology 2009;137(1):361-71, 371.e1-5.
2009: Rainer Hamacher; Sandra Diersch; Melanie Scheibel; Florian Eckel; Martina Mayr; Roland Rad; Monther Bajbouj; Roland M Schmid; Dieter Saur; Günter Schneider
Interleukin 1 beta gene promoter SNPs are associated with risk of pancreatic cancer.
Cytokine 2009;46(2):182-6.
2008: Johannes von Burstin; Stefan Eser; Barbara Seidler; Alexander Meining; Monther Bajbouj; Jörg Mages; Roland Lang; Alexander J Kind; Angelika E Schnieke; Roland M Schmid; Günter Schneider; Dieter Saur
Highly sensitive detection of early-stage pancreatic cancer by multimodal near-infrared molecular imaging in living mice.
International journal of cancer. Journal international du cancer 2008;123(9):2138-47.
2008: Ulrich Mayr; Alexander von Werder; Barbara Seidler; Wolfgang Reindl; Monther Bajbouj; Roland M Schmid; Günter Schneider; Dieter Saur
RCAS-mediated retroviral gene delivery: a versatile tool for the study of gene function in a mouse model of pancreatic cancer.
Human gene therapy 2008;19(9):896-906.
2008: Barbara Seidler; Annegret Schmidt; Ulrich Mayr; Hassan Nakhai; Roland M Schmid; Günter Schneider; Dieter Saur
A Cre-loxP-based mouse model for conditional somatic gene expression and knockdown in vivo by using avian retroviral vectors.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(29):10137-42.
2008: Günter Schneider; Rainer Hamacher; Stefan Eser; Helmut Friess; Roland M Schmid; Dieter Saur
Molecular biology of pancreatic cancer--new aspects and targets.
Anticancer research 2008;28(3A):1541-50.
2008: Rainer Hamacher; Roland M Schmid; Dieter Saur; Günter Schneider
Apoptotic pathways in pancreatic ductal adenocarcinoma.
Molecular cancer 2008;7():64.
2007: Rainer Hamacher; Dieter Saur; Ralph Fritsch; Maximilian Reichert; Roland M Schmid; Günter Schneider
Casein kinase II inhibition induces apoptosis in pancreatic cancer cells.
Oncology reports 2007;18(3):695-701.
2007: Ralph Fritsch; Günter Schneider; Dieter Saur; Melanie Scheibel; Roland M Schmid
Translational repression of MCL-1 couples stress-induced eIF2 alpha phosphorylation to mitochondrial apoptosis initiation.
The Journal of biological chemistry 2007;282(31):22551-62.
2007: Günter Schneider; Maximilian Reichert; Dieter Saur; Rainer Hamacher; Ralph Fritsch; Roland M Schmid
HDAC3 is linked to cell cycle machinery in MiaPaCa2 cells by regulating transcription of skp2.
Cell proliferation 2007;40(4):522-31.
2007: Sebastian Kolb; Ralph Fritsch; Dieter Saur; Maximilian Reichert; Roland M Schmid; Günter Schneider
HMGA1 controls transcription of insulin receptor to regulate cyclin D1 translation in pancreatic cancer cells.
Cancer research 2007;67(10):4679-86.
2007: Maximilian Reichert; Dieter Saur; Rainer Hamacher; Roland M Schmid; Günter Schneider
Phosphoinositide-3-kinase signaling controls S-phase kinase-associated protein 2 transcription via E2F1 in pancreatic ductal adenocarcinoma cells.
Cancer research 2007;67(9):4149-56.
2006: Günter Schneider; Dieter Saur; Jens T Siveke; Ralph Fritsch; Florian R Greten; Roland M Schmid
IKKalpha controls p52/RelB at the skp2 gene promoter to regulate G1- to S-phase progression.
The EMBO journal 2006;25(16):3801-12.
2006: Günter Schneider; Andreas Weber; Ulrich Zechner; Franz Oswald; Helmut M Friess; Roland M Schmid; Susanne Liptay
GADD45alpha is highly expressed in pancreatic ductal adenocarcinoma cells and required for tumor cell viability.
International journal of cancer. Journal international du cancer 2006;118(10):2405-11.
2005: Günter Schneider; Jens T Siveke; Florian Eckel; Roland M Schmid
Pancreatic cancer: basic and clinical aspects.
Gastroenterology 2005;128(6):1606-25.