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Pascal Schneider

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Maria Pellegrini; M Perroud; Pascal Schneider; Kathy Strauch; Laure Willen; Hernan Cuervo; Eric S Day; Dennis Krushinskie; Timothy S Zheng
Structure of the extracellular domains of human and Xenopus Fn14: implications in the evolution of TWEAK and Fn14 interactions.
Benjamin Joachim Schmiedel; Pascal Schneider; Julia Steinbacher; Constantin Maximilian Wende; Miyuki Azuma; Ludger Grosse-Hovest; Alexandra Malinovska; Tina Nuebling; Helmut R Salih
Receptor activator for NF-κB ligand in acute myeloid leukemia: expression, function, and modulation of NK cell immunosurveillance.
Benjamin Joachim Schmiedel; Pascal Schneider; Stefan Wirths; Carolin Andrea Scheible; Miyuki Azuma; Ludger Grosse-Hovest; Gundram Jung; Hans-Georg Kopp; Tina Nuebling; Helmut R Salih
RANKL expression, function, and therapeutic targeting in multiple myeloma and chronic lymphocytic leukemia.

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2013: Maria Pellegrini; M Perroud; Pascal Schneider; Kathy Strauch; Laure Willen; Hernan Cuervo; Eric S Day; Dennis Krushinskie; Timothy S Zheng
Structure of the extracellular domains of human and Xenopus Fn14: implications in the evolution of TWEAK and Fn14 interactions.
The FEBS journal 2013;280(8):1818-29.
2013: Benjamin Joachim Schmiedel; Pascal Schneider; Julia Steinbacher; Constantin Maximilian Wende; Miyuki Azuma; Ludger Grosse-Hovest; Alexandra Malinovska; Tina Nuebling; Helmut R Salih
Receptor activator for NF-κB ligand in acute myeloid leukemia: expression, function, and modulation of NK cell immunosurveillance.
Journal of immunology (Baltimore, Md. : 1950) 2013;190(2):821-31.
2013: Benjamin Joachim Schmiedel; Pascal Schneider; Stefan Wirths; Carolin Andrea Scheible; Miyuki Azuma; Ludger Grosse-Hovest; Gundram Jung; Hans-Georg Kopp; Tina Nuebling; Helmut R Salih
RANKL expression, function, and therapeutic targeting in multiple myeloma and chronic lymphocytic leukemia.
Cancer research 2013;73(2):683-94.
2013: Josquin Nys; Cristian R Smulski; Aubry Tardivel; Laure Willen; Olivier Donzé; Henry Hess; Bertrand Huard; Christine Kowalczyk; Pascal Schneider
No Evidence That Soluble TACI Induces Signalling via Membrane-Expressed BAFF and APRIL in Myeloid Cells.
PloS one 2013;8(4):e61350.
2012: Stefan K Drexler; Olaf Gross; Heiko Hermeking; Rene Jackstadt; Mark Masin; Pascal Schneider; Aubry Tardivel; Jurg Tschopp; Luca Bonsignore; Amir S Yazdi
Tissue-specific opposing functions of the inflammasome adaptor ASC in the regulation of epithelial skin carcinogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(45):18384-9.
2012: L X Heinz; Manfredo Quadroni; M Rebsamen; D C Rossi; Pascal Schneider; Kate Schroder; F Staehli; O Gross; Jürg Tschopp
The death domain-containing protein Unc5CL is a novel MyD88-independent activator of the pro-inflammatory IRAK signaling cascade.
Cell death and differentiation 2012;19(4):722-31.
2011: Christine Kowalczyk; Elizabeth A Mauldin; Aubry Tardivel; Laure Willen; Giovanna Badic; Margret L Casal; Stéphane Demotz; Nathalie Dunkel; Anne-Lise Etter; Manuel Favre; Olivier Gaide; Denis J Headon; Douglas M Jefferson; Pascal Schneider
Molecular and therapeutic characterization of anti-ectodysplasin A receptor (EDAR) agonist monoclonal antibodies.
The Journal of biological chemistry 2011;286(35):30769-79.
2011: Claudia Bossen; Aubry Tardivel; Laure Willen; Carrie A Fletcher; M Perroud; Friedrich Beermann; Antonius G Rolink; Martin L Scott; Fabienne Mackay; Pascal Schneider
Mutation of the BAFF furin cleavage site impairs B-cell homeostasis and antibody responses.
European journal of immunology 2011;41(3):787-97.
2011: Silvia A Fuertes Marraco; Annette Ives; Elisa S Jansen; Slavica Masina; Lorraine A O'Reilly; Pascal Schneider; Clare L Scott; Ken Shortman; Andreas Strasser; David Vremec; Philippe Bouillet; Nicolas Fasel; Hans Acha-Orbea
Type I interferon drives dendritic cell apoptosis via multiple BH3-only proteins following activation by PolyIC in vivo.
PloS one 2011;6(6):e20189.
2009: Jonathan Back; Emilio L Malchiodi; Sangwoo Cho; Léonardo Scarpellino; Pascal Schneider; Melissa C Kerzic; Roy A Mariuzza; Werner Held
Distinct conformations of Ly49 natural killer cell receptors mediate MHC class I recognition in trans and cis.
Immunity 2009;31(4):598-608.
2009: Lee Kim Swee; Karine Ingold-Salamin; Aubry Tardivel; Laure Willen; Olivier Gaide; Manuel Favre; Stéphane Demotz; Marja Mikkola; Pascal Schneider
Biological activity of ectodysplasin A is conditioned by its collagen and heparan sulfate proteoglycan-binding domains.
The Journal of biological chemistry 2009;284(40):27567-76.
2009: Elizabeth A Mauldin; Olivier Gaide; Pascal Schneider; Margret L Casal
Neonatal treatment with recombinant ectodysplasin prevents respiratory disease in dogs with X-linked ectodermal dysplasia.
American journal of medical genetics. Part A 2009;149A(9):2045-9.
2009: Greta Guarda; Catherine Dostert; Francesco Staehli; Katrin Cabalzar; Rosa Castillo; Aubry Tardivel; Pascal Schneider; Jürg Tschopp
T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes.
Nature 2009;460(7252):269-73.
2008: Bertrand Huard; Thomas McKee; Carine Bosshard; Stéphane Durual; Thomas Matthes; Samir Myit; Olivier Donze; Christophe P Frossard; Carlo Chizzolini; Christiane Favre; Rudolf H Zubler; Jean Philippe Guyot; Pascal Schneider; Eddy Roosnek
APRIL secreted by neutrophils binds to heparan sulfate proteoglycans to create plasma cell niches in human mucosa.
The Journal of clinical investigation 2008;118(8):2887-95.
2008: Elodie Belnoue; Maria Pihlgren; Tracy L McGaha; Chantal Tougne; Anne-Françoise Rochat; Claudia Bossen; Pascal Schneider; Bertrand Huard; Paul-Henri Lambert; Claire-Anne Siegrist
APRIL is critical for plasmablast survival in the bone marrow and poorly expressed by early-life bone marrow stromal cells.
Blood 2008;111(5):2755-64.
2008: Claudia Bossen; Teresa G Cachero; Aubry Tardivel; Karine Ingold; Laure Willen; Max Dobles; Martin L Scott; Aris Maquelin; Elodie Belnoue; Claire-Anne Siegrist; Stéphane Chevrier; Hans Acha-Orbea; Helen Leung; Fabienne Mackay; Jürg Tschopp; Pascal Schneider
TACI, unlike BAFF-R, is solely activated by oligomeric BAFF and APRIL to support survival of activated B cells and plasmablasts.
Blood 2008;111(3):1004-12.
2007: Margret L Casal; John R Lewis; Elizabeth A Mauldin; Aubry Tardivel; Karine Ingold; Manuel Favre; Fabrice Paradies; Stephane Demotz; Olivier Gaide; Pascal Schneider
Significant correction of disease after postnatal administration of recombinant ectodysplasin A in canine X-linked ectodermal dysplasia.
American journal of human genetics 2007;81(5):1050-6.
2007: J Alain Kummer; Olivier Micheau; Pascal Schneider; N Bovenschen; Roel Broekhuizen; R Quadir; Merel C M Strik; C Erik Hack; Jürg Tschopp
Ectopic expression of the serine protease inhibitor PI9 modulates death receptor-mediated apoptosis.
Cell death and differentiation 2007;14(8):1486-96.
2007: Sonja Kothlow; Iris Morgenroth; Yvonne Graef; Kirsten Schneider; Ingrid Riehl; Peter Staeheli; Pascal Schneider; Bernd Kaspers
Unique and conserved functions of B cell-activating factor of the TNF family (BAFF) in the chicken.
International immunology 2007;19(2):203-15.
2006: Mahasweta Girgenrath; Shawn Weng; Christine A Kostek; Beth Browning; Monica Wang; Sharron A N Brown; Jeffrey A Winkles; Jennifer S Michaelson; Normand E Allaire; Pascal Schneider; Martin L Scott; Yen-Ming Hsu; Hideo Yagita; Richard A Flavell; Jeffrey Boone Miller; Linda C Burkly; Timothy S Zheng
TWEAK, via its receptor Fn14, is a novel regulator of mesenchymal progenitor cells and skeletal muscle regeneration.
The EMBO journal 2006;25(24):5826-39.
2006: Claudia Bossen; Pascal Schneider
BAFF, APRIL and their receptors: structure, function and signaling.
Seminars in immunology 2006;18(5):263-75.
2006: Chunyan Mou; Ben Jackson; Pascal Schneider; Paul A Overbeek; Denis J Headon
Generation of the primary hair follicle pattern.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(24):9075-80.
2006: Claudia Bossen; Karine Ingold; Aubry Tardivel; Jean-Luc Bodmer; Olivier Gaide; Sylvie Hertig; Christine Ambrose; Jürg Tschopp; Pascal Schneider
Interactions of tumor necrosis factor (TNF) and TNF receptor family members in the mouse and human.
The Journal of biological chemistry 2006;281(20):13964-71.
2006: Teresa G Cachero; Ian M Schwartz; Fang Qian; Eric S Day; Claudia Bossen; Karine Ingold; Aubry Tardivel; Dennis Krushinskie; John Eldredge; Laura Silvian; Alexey A Lugovskoy; Graham K Farrington; Kathy Strauch; Pascal Schneider; Adrian Whitty
Formation of virus-like clusters is an intrinsic property of the tumor necrosis factor family member BAFF (B cell activating factor).
Biochemistry 2006;45(7):2006-13.
2005: Krisztian Kvell; Tuan Huy Nguyen; Patrick Salmon; Frédéric Glauser; Christiane Werner-Favre; Marc Barnet; Pascal Schneider; Didier Trono; Rudolf H Zubler
Transduction of CpG DNA-stimulated primary human B cells with bicistronic lentivectors.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;12(5):892-9.
2005: Marek Cebecauer; Philippe Guillaume; Pavel Hozak; Silke Mark; Helen Everett; Pascal Schneider; Immanuel F Luescher
Soluble MHC-peptide complexes induce rapid death of CD8+ CTL.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(11):6809-19.
2005: Pascal Schneider
The role of APRIL and BAFF in lymphocyte activation.
Current opinion in immunology 2005;17(3):282-9.
2005: Karine Ingold; Adrian Zumsteg; Aubry Tardivel; Bertrand Huard; Quynh-Giao Steiner; Teresa G Cachero; Fang Qiang; Leonid Gorelik; Susan L Kalled; Hans Acha-Orbea; Paul D Rennert; Jürg Tschopp; Pascal Schneider
Identification of proteoglycans as the APRIL-specific binding partners.
The Journal of experimental medicine 2005;201(9):1375-83.
2004: Aubry Tardivel; Antoine Tinel; Susanne M A Lens; Quynh-Giao Steiner; Estelle Sauberli; Anne Wilson; Fabienne Mackay; Antonius G Rolink; Friedrich Beermann; Jürg Tschopp; Pascal Schneider
The anti-apoptotic factor Bcl-2 can functionally substitute for the B cell survival but not for the marginal zone B cell differentiation activity of BAFF.
European journal of immunology 2004;34(2):509-18.
2004: Marcel Batten; Carrie Fletcher; Lai Guan Ng; Joanna Groom; Julie Wheway; Yacine LAABI; Xiaoguan Xin; Pascal Schneider; Jürg Tschopp; Charles R Mackay; Fabienne Mackay
TNF deficiency fails to protect BAFF transgenic mice against autoimmunity and reveals a predisposition to B cell lymphoma.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(2):812-22.
2004: Kirsten Schneider; Sonja Kothlow; Pascal Schneider; Aubry Tardivel; Thomas W Göbel; Bernd Kaspers; Peter Staeheli
Chicken BAFF--a highly conserved cytokine that mediates B cell survival.
International immunology 2004;16(1):139-48.
2003: Pascal Schneider; Jürg Tschopp
BAFF and the regulation of B cell survival.
Immunology letters 2003;88(1):57-62.
2003: Olivier Gaide; Pascal Schneider
Permanent correction of an inherited ectodermal dysplasia with recombinant EDA.
Nature medicine 2003;9(5):614-8.
2003: Craig R Brunetti; Mini Paulose-Murphy; Rajkumari Singh; Jing Qin; John W Barrett; Aubry Tardivel; Pascal Schneider; Karim Essani; Grant McFadden
A secreted high-affinity inhibitor of human TNF from Tanapox virus.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(8):4831-6.
2003: Pascal Schneider; Dian Olson; Aubry Tardivel; Beth Browning; Alexey A Lugovskoy; DaHai Gong; Max Dobles; Sylvie Hertig; Kay Hofmann; Herman van Vlijmen; Yen-Ming Hsu; Linda C Burkly; Jürg Tschopp; Timothy S Zheng
Identification of a new murine tumor necrosis factor receptor locus that contains two novel murine receptors for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL).
The Journal of biological chemistry 2003;278(7):5444-54.
2003: Nils Holler; Aubry Tardivel; Magdalena Kovacsovics-Bankowski; Sylvie Hertig; Olivier Gaide; Fabio Martinon; Antoine Tinel; David Deperthes; Silvio Calderara; Therese Schulthess; Jürgen Engel; Pascal Schneider; Jürg Tschopp
Two adjacent trimeric Fas ligands are required for Fas signaling and formation of a death-inducing signaling complex.
Molecular and cellular biology 2003;23(4):1428-40.
2002: Olivier Micheau; Margot Thome; Pascal Schneider; Nils Holler; Jürg Tschopp; Donald W Nicholson; Christophe Briand; Markus G Grütter
The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex.
The Journal of biological chemistry 2002;277(47):45162-71.
2002: Merel C M Strik; Bellinda A Bladergroen; Dorine Wouters; Walter Kisiel; Jan Hendrik Hooijberg; Angelique R Verlaan; Peter L Hordijk; Pascal Schneider; C Erik Hack; J Alain Kummer
Distribution of the human intracellular serpin protease inhibitor 8 in human tissues.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2002;50(11):1443-54.
2002: Bente Lowin-Kropf; Béatrice Kunz; Pascal Schneider; Werner Held
A role for the src family kinase Fyn in NK cell activation and the formation of the repertoire of Ly49 receptors.
European journal of immunology 2002;32(3):773-82.
2002: Jean-Luc Bodmer; Pascal Schneider; Jürg Tschopp
The molecular architecture of the TNF superfamily.
Trends in biochemical sciences 2002;27(1):19-26.
2002: Joanna Groom; Susan L Kalled; Anne H Cutler; Carl Olson; Stephen A Woodcock; Pascal Schneider; Jürg Tschopp; Teresa G Cachero; Marcel Batten; Julie Wheway; Davide Mauri; Dana Cavill; Tom P Gordon; Charles R Mackay; Fabienne Mackay
Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjögren's syndrome.
The Journal of clinical investigation 2002;109(1):59-68.
2001: Pascal Schneider; H Takatsuka; Anne Wilson; Fabienne Mackay; Aubry Tardivel; Susanne M A Lens; Teresa G Cachero; Daniela Finke; Friedrich Beermann; Jürg Tschopp
Maturation of marginal zone and follicular B cells requires B cell activating factor of the tumor necrosis factor family and is independent of B cell maturation antigen.
The Journal of experimental medicine 2001;194(11):1691-7.
2001: Jeffrey S Thompson; Sarah A Bixler; Fang Qian; Kalpit A Vora; Martin L Scott; Teresa G Cachero; Cathy Hession; Pascal Schneider; Irene Sizing; Colleen Mullen; Kathy Strauch; Mohammad Zafari; Christopher D Benjamin; Jürg Tschopp; Jeffrey L Browning; Christine Ambrose
BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF.
Science (New York, N.Y.) 2001;293(5537):2108-11.
2001: Pascal Schneider; S L Street; Olivier Gaide; Sylvie Hertig; Aubry Tardivel; Jürg Tschopp; L Runkel; K Alevizopoulos; Betsy M Ferguson; Jonathan (Jon) Zonana
Mutations leading to X-linked hypohidrotic ectodermal dysplasia affect three major functional domains in the tumor necrosis factor family member ectodysplasin-A.
The Journal of biological chemistry 2001;276(22):18819-27.
2001: Christiane Werner-Favre; Fabrice Bovia; Pascal Schneider; Nils Holler; Marc Barnet; Vincent Kindler; Jürg Tschopp; Rudolf H Zubler
IgG subclass switch capacity is low in switched and in IgM-only, but high in IgD+IgM+, post-germinal center (CD27+) human B cells.
European journal of immunology 2001;31(1):243-9.
2000: Paul D Rennert; Pascal Schneider; Teresa G Cachero; J Thompson; L Trabach; Sylvie Hertig; Nils Holler; Fang Qian; Colleen Mullen; Kathy Strauch; Jeffrey L Browning; Christine Ambrose; Jürg Tschopp
A soluble form of B cell maturation antigen, a receptor for the tumor necrosis factor family member APRIL, inhibits tumor cell growth.
The Journal of experimental medicine 2000;192(11):1677-84.
2000: Nils Holler; Rossana Zaru; Olivier Micheau; Margot Thome; Antoine Attinger; Salvatore Valitutti; Jean-Luc Bodmer; Pascal Schneider; B Seed; Jürg Tschopp
Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule.
Nature immunology 2000;1(6):489-95.
2000: Marcel Batten; Joanna Groom; Teresa G Cachero; Fang Qian; Pascal Schneider; Jürg Tschopp; Jeffrey L Browning; Fabienne Mackay
BAFF mediates survival of peripheral immature B lymphocytes.
The Journal of experimental medicine 2000;192(10):1453-66.
2000: Abigail S Tucker; Denis J Headon; Pascal Schneider; Betsy M Ferguson; Paul A Overbeek; Jürg Tschopp; Paul T Sharpe
Edar/Eda interactions regulate enamel knot formation in tooth morphogenesis.
Development (Cambridge, England) 2000;127(21):4691-700.
2000: V Rochat-Steiner; K Becker; Olivier Micheau; Pascal Schneider; Kimberly Burns; Jürg Tschopp
FIST/HIPK3: a Fas/FADD-interacting serine/threonine kinase that induces FADD phosphorylation and inhibits fas-mediated Jun NH(2)-terminal kinase activation.
The Journal of experimental medicine 2000;192(8):1165-74.
2000: F Mühlenbeck; Pascal Schneider; J L Bodmer; Ralph Schwenzer; A Hauser; G Schubert; Peter Scheurich; Dieter Moosmayer; Jürg Tschopp; Harald Wajant
The tumor necrosis factor-related apoptosis-inducing ligand receptors TRAIL-R1 and TRAIL-R2 have distinct cross-linking requirements for initiation of apoptosis and are non-redundant in JNK activation.
The Journal of biological chemistry 2000;275(41):32208-13.
2000: Jean-Luc Bodmer; P Meier; Jürg Tschopp; Pascal Schneider
Cysteine 230 is essential for the structure and activity of the cytotoxic ligand TRAIL.
The Journal of biological chemistry 2000;275(27):20632-7.
2000: Jeffrey S Thompson; Pascal Schneider; Susan L Kalled; L Wang; Eric A Lefevre; Teresa G Cachero; Fabienne Mackay; Sarah A Bixler; Mohammad Zafari; Z Y Liu; Stephen A Woodcock; Fang Qian; Marcel Batten; Christine Madry; Yolande Richard; Christopher D Benjamin; Jeffrey L Browning; Andréas Tsapis; Jürg Tschopp; Christine Ambrose
BAFF binds to the tumor necrosis factor receptor-like molecule B cell maturation antigen and is important for maintaining the peripheral B cell population.
The Journal of experimental medicine 2000;192(1):129-35.
2000: Nils Holler; Takao Kataoka; Jean-Luc Bodmer; Pedro Romero; J Romero; David Deperthes; J Engel; Jürg Tschopp; Pascal Schneider
Development of improved soluble inhibitors of FasL and CD40L based on oligomerized receptors.
Journal of immunological methods 2000;237(1-2):159-73.
2000: Jean-Luc Bodmer; Nils Holler; S Reynard; Patrizia Vinciguerra; Pascal Schneider; Peter Juo; John Blenis; Jürg Tschopp
TRAIL receptor-2 signals apoptosis through FADD and caspase-8.
Nature cell biology 2000;2(4):241-3.
2000: Pascal Schneider; Jürg Tschopp
Modulation of death receptor signalling.
Symposia of the Society for Experimental Biology 2000;52():31-42.
2000: Pascal Schneider
Production of recombinant TRAIL and TRAIL receptor: Fc chimeric proteins.
Methods in enzymology 2000;322():325-45.
1999: Fabienne Mackay; Stephen A Woodcock; P Lawton; Christine Ambrose; Manfred Baetscher; Pascal Schneider; Jürg Tschopp; Jeffrey L Browning
Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations.
The Journal of experimental medicine 1999;190(11):1697-710.
1999: Sally Corradin; Adriana Ransijn; Giampietro Corradin; Mario Roggero; A A Schmitz; Pascal Schneider; Jacques Mauël; Guy Vergères
MARCKS-related protein (MRP) is a substrate for the Leishmania major surface protease leishmanolysin (gp63).
The Journal of biological chemistry 1999;274(36):25411-8.
1999: Pascal Schneider; Fabienne Mackay; V Steiner; Kay Hofmann; Jean-Luc Bodmer; Nils Holler; Christine Ambrose; P Lawton; Sarah A Bixler; Hans Acha-Orbea; Danila Valmori; Pedro Romero; Christiane Werner-Favre; Rudolf H Zubler; Jeffrey L Browning; Jürg Tschopp
BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth.
The Journal of experimental medicine 1999;189(11):1747-56.
1999: Pascal Schneider; Ralph Schwenzer; E Haas; F Mühlenbeck; G Schubert; Peter Scheurich; Jürg Tschopp; Harald Wajant
TWEAK can induce cell death via endogenous TNF and TNF receptor 1.
European journal of immunology 1999;29(6):1785-92.
1999: Margot Thome; Fabio Martinon; Kay Hofmann; V Rubio; V Steiner; Pascal Schneider; C Mattmann; Jürg Tschopp
Equine herpesvirus-2 E10 gene product, but not its cellular homologue, activates NF-kappaB transcription factor and c-Jun N-terminal kinase.
The Journal of biological chemistry 1999;274(15):9962-8.
1998: Takao Kataoka; M Schröter; Michael Hahne; Pascal Schneider; M Irmler; Margot Thome; Christopher J Froelich; Jürg Tschopp
FLIP prevents apoptosis induced by death receptors but not by perforin/granzyme B, chemotherapeutic drugs, and gamma irradiation.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(8):3936-42.
1998: Michael Hahne; Takao Kataoka; M Schröter; Kay Hofmann; M Irmler; Jean-Luc Bodmer; Pascal Schneider; T Bornand; Nils Holler; Lars E French; Bernard Sordat; Donata Rimoldi; Jürg Tschopp
APRIL, a new ligand of the tumor necrosis factor family, stimulates tumor cell growth.
The Journal of experimental medicine 1998;188(6):1185-90.
1998: Kimberly Burns; Fabio Martinon; Christoph Esslinger; H Pahl; Pascal Schneider; Jean-Luc Bodmer; F Di Marco; L French; Jürg Tschopp
MyD88, an adapter protein involved in interleukin-1 signaling.
The Journal of biological chemistry 1998;273(20):12203-9.
1998: Pascal Schneider; Nils Holler; Jean-Luc Bodmer; Michael Hahne; Karl Frei; A Fontana; Jürg Tschopp
Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity.
The Journal of experimental medicine 1998;187(8):1205-13.
1997: Pascal Schneider; Margot Thome; Kimberly Burns; Jean-Luc Bodmer; Kay Hofmann; Takao Kataoka; Nils Holler; Jürg Tschopp
TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappaB.
Immunity 1997;7(6):831-6.
1997: Pascal Schneider; Jean-Luc Bodmer; Margot Thome; Kay Hofmann; Nils Holler; Jürg Tschopp
Characterization of two receptors for TRAIL.
FEBS letters 1997;416(3):329-34.
1997: Pascal Schneider; Jean-Luc Bodmer; Nils Holler; C Mattmann; P Scuderi; Alexey V Terskikh; Manuel Peitsch; Jürg Tschopp
Characterization of Fas (Apo-1, CD95)-Fas ligand interaction.
The Journal of biological chemistry 1997;272(30):18827-33.
1997: K Becker; Pascal Schneider; Kay Hofmann; C Mattmann; Jürg Tschopp
Interaction of Fas(Apo-1/CD95) with proteins implicated in the ubiquitination pathway.
FEBS letters 1997;412(1):102-6.
1997: M Irmler; Margot Thome; Michael Hahne; Pascal Schneider; Kay Hofmann; V Steiner; Jean-Luc Bodmer; M Schröter; Kimberly Burns; C Mattmann; Donata Rimoldi; Lars E French; Jürg Tschopp
Inhibition of death receptor signals by cellular FLIP.
Nature 1997;388(6638):190-5.
1997: Margot Thome; Pascal Schneider; Kay Hofmann; Helmut Fickenscher; Edgar Meinl; Frank Neipel; C Mattmann; Kimberly Burns; Jean-Luc Bodmer; M Schröter; C Scaffidi; Peter H Krammer; Marcus E Peter; Jürg Tschopp
Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors.
Nature 1997;386(6624):517-21.
1997: Jean-Luc Bodmer; Kimberly Burns; Pascal Schneider; Kay Hofmann; V Steiner; Margot Thome; T Bornand; Michael Hahne; M Schröter; K Becker; Anne Wilson; Lars E French; Jeffrey L Browning; H Robson MacDonald; Jürg Tschopp
TRAMP, a novel apoptosis-mediating receptor with sequence homology to tumor necrosis factor receptor 1 and Fas(Apo-1/CD95).
Immunity 1997;6(1):79-88.
1996: Michael Hahne; Donata Rimoldi; M Schröter; Pedro Romero; M Schreier; Lars E French; Pascal Schneider; T Bornand; A Fontana; D Lienard; Jean-Charles Cerottini; Jürg Tschopp
Melanoma cell expression of Fas(Apo-1/CD95) ligand: implications for tumor immune escape.
Science (New York, N.Y.) 1996;274(5291):1363-6.
1995: Y Buchmüller-Rouiller; S B Corrandin; J Smith; Pascal Schneider; Adriana Ransijn; Victor Jongeneel; Jacques Mauël
Role of glutathione in macrophage activation: effect of cellular glutathione depletion on nitrite production and leishmanicidal activity.
Cellular immunology 1995;164(1):73-80.
1995: J Bouvier; Pascal Schneider; R Etges
Leishmanolysin: surface metalloproteinase of Leishmania.
Methods in enzymology 1995;248():614-33.
1995: Pascal Schneider; Michael A J Ferguson
Microscale analysis of glycosylphosphatidylinositol structures.
Methods in enzymology 1995;250():614-30.
1993: Pascal Schneider; T A Glaser
Characterisation of two soluble metalloexopeptidases in the protozoan parasite Leishmania major.
Molecular and biochemical parasitology 1993;62(2):223-31.
1993: Pascal Schneider; T A Glaser
Characterization of a surface metalloprotease from Herpetomonas samuelpessoai and comparison with Leishmania major promastigote surface protease.
Molecular and biochemical parasitology 1993;58(2):277-82.
1992: Pascal Schneider; J P Rosat; J Bouvier; Jacques Louis; C Bordier
Leishmania major: differential regulation of the surface metalloprotease in amastigote and promastigote stages.
Experimental parasitology 1992;75(2):196-206.
1992: Y Buchmüller-Rouiller; Pascal Schneider; S Betz-Corradin; J Smith; Jacques Mauël
3-amino-1,2,4-triazole inhibits macrophage NO synthase.
Biochemical and biophysical research communications 1992;183(1):150-5.
1992: Pascal Schneider; C Bordier; R Etges
Membrane proteins and enzymes of Leishmania.
Sub-cellular biochemistry 1992;18():39-72.
1990: J Bouvier; Pascal Schneider; R Etges; C Bordier
Peptide substrate specificity of the membrane-bound metalloprotease of Leishmania.
Biochemistry 1990;29(43):10113-9.
1990: Pascal Schneider; Michael A J Ferguson; Malcolm J McConville; Angela Mehlert; Steve W Homans; C Bordier
Structure of the glycosyl-phosphatidylinositol membrane anchor of the Leishmania major promastigote surface protease.
The Journal of biological chemistry 1990;265(28):16955-64.