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Pascal Schneider
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44
Tschopp, Jürg
16
Bodmer, Jean-Luc
14
Tardivel, Aubry
13
Holler, Nils
10
Hofmann, Kay
9
Cachero, Teresa
9
Mackay, Fabienne
9
Thome, Margot
7
Browning, Jeffrey
7
Gaide, Olivier
6
Burns, Kimberly
6
Hahne, Michael
6
Ambrose, Christine
6
Schröter, M
5
Qian, Fang
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All Publications
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2009: Back Jonathan; Malchiodi Emilio L; Cho Sangwoo; Scarpellino Léonardo; Schneider Pascal; Kerzic Melissa C; Mariuzza Roy A; Held Werner
Distinct conformations of Ly49 natural killer cell receptors mediate MHC class I recognition in trans and cis.
Immunity 2009;31(4):598-608.
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2009: Swee Lee Kim; Ingold-Salamin Karine; Tardivel Aubry; Willen Laure; Gaide Olivier; Favre Manuel; Demotz Stéphane; Mikkola Marja; Schneider Pascal
Biological activity of ectodysplasin A is conditioned by its collagen and heparan sulfate proteoglycan-binding domains.
The Journal of biological chemistry 2009;284(40):27567-76.
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2009: Mauldin Elizabeth A; Gaide Olivier; Schneider Pascal; Casal Margret L
Neonatal treatment with recombinant ectodysplasin prevents respiratory disease in dogs with X-linked ectodermal dysplasia.
American journal of medical genetics. Part A 2009;149A(9):2045-9.
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2009: Guarda Greta; Dostert Catherine; Staehli Francesco; Cabalzar Katrin; Castillo Rosa; Tardivel Aubry; Schneider Pascal; Tschopp Jürg
T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes.
Nature 2009;460(7252):269-73.
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2008: Huard Bertrand; McKee Thomas; Bosshard Carine; Durual Stéphane; Matthes Thomas; Myit Samir; Donze Olivier; Frossard Christophe; Chizzolini Carlo; Favre Christiane; Zubler Rudolf; Guyot Jean Philippe; Schneider Pascal; Roosnek Eddy
APRIL secreted by neutrophils binds to heparan sulfate proteoglycans to create plasma cell niches in human mucosa.
The Journal of clinical investigation 2008;118(8):2887-95.
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2008: Belnoue Elodie; Pihlgren Maria; McGaha Tracy L; Tougne Chantal; Rochat Anne-Françoise; Bossen Claudia; Schneider Pascal; Huard Bertrand; Lambert Paul-Henri; Siegrist Claire-Anne
APRIL is critical for plasmablast survival in the bone marrow and poorly expressed by early-life bone marrow stromal cells.
Blood 2008;111(5):2755-64.
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2008: Bossen Claudia; Cachero Teresa G; Tardivel Aubry; Ingold Karine; Willen Laure; Dobles Max; Scott Martin L; Maquelin Aris; Belnoue Elodie; Siegrist Claire-Anne; Chevrier Stéphane; Acha-Orbea Hans; Leung Helen; Mackay Fabienne; Tschopp Jürg; Schneider Pascal
TACI, unlike BAFF-R, is solely activated by oligomeric BAFF and APRIL to support survival of activated B cells and plasmablasts.
Blood 2008;111(3):1004-12.
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2007: Casal Margret L; Lewis John R; Mauldin Elizabeth A; Tardivel Aubry; Ingold Karine; Favre Manuel; Paradies Fabrice; Demotz Stephane; Gaide Olivier; Schneider Pascal
Significant correction of disease after postnatal administration of recombinant ectodysplasin A in canine X-linked ectodermal dysplasia.
American journal of human genetics 2007;81(5):1050-6.
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2007: Kummer J A; Micheau O; Schneider P; Bovenschen N; Broekhuizen R; Quadir R; Strik M C M; Hack C E; Tschopp J
Ectopic expression of the serine protease inhibitor PI9 modulates death receptor-mediated apoptosis.
Cell death and differentiation 2007;14(8):1486-96.
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2007: Kothlow Sonja; Morgenroth Iris; Graef Yvonne; Schneider Kirsten; Riehl Ingrid; Staeheli Peter; Schneider Pascal; Kaspers Bernd
Unique and conserved functions of B cell-activating factor of the TNF family (BAFF) in the chicken.
International immunology 2007;19(2):203-15.
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2006: Girgenrath Mahasweta; Weng Shawn; Kostek Christine A; Browning Beth; Wang Monica; Brown Sharron A N; Winkles Jeffrey A; Michaelson Jennifer S; Allaire Norm; Schneider Pascal; Scott Martin L; Hsu Yen-ming; Yagita Hideo; Flavell Richard A; Miller Jeffrey Boone; Burkly Linda C; Zheng Timothy S
TWEAK, via its receptor Fn14, is a novel regulator of mesenchymal progenitor cells and skeletal muscle regeneration.
The EMBO journal 2006;25(24):5826-39.
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2006: Bossen Claudia; Schneider Pascal
BAFF, APRIL and their receptors: structure, function and signaling.
Seminars in immunology 2006;18(5):263-75.
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2006: Mou Chunyan; Jackson Ben; Schneider Pascal; Overbeek Paul A; Headon Denis J
Generation of the primary hair follicle pattern.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(24):9075-80.
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2006: Bossen Claudia; Ingold Karine; Tardivel Aubry; Bodmer Jean-Luc; Gaide Olivier; Hertig Sylvie; Ambrose Christine; Tschopp Jürg; Schneider Pascal
Interactions of tumor necrosis factor (TNF) and TNF receptor family members in the mouse and human.
The Journal of biological chemistry 2006;281(20):13964-71.
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2006: Cachero Teresa G; Schwartz Ian M; Qian Fang; Day Eric S; Bossen Claudia; Ingold Karine; Tardivel Aubry; Krushinskie Dennis; Eldredge John; Silvian Laura; Lugovskoy Alexey; Farrington Graham K; Strauch Kathy; Schneider Pascal; Whitty Adrian
Formation of virus-like clusters is an intrinsic property of the tumor necrosis factor family member BAFF (B cell activating factor).
Biochemistry 2006;45(7):2006-13.
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2005: Kvell Krisztian; Nguyen Tuan H; Salmon Patrick; Glauser Frédéric; Werner-Favre Christiane; Barnet Marc; Schneider Pascal; Trono Didier; Zubler Rudolf H
Transduction of CpG DNA-stimulated primary human B cells with bicistronic lentivectors.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;12(5):892-9.
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2005: Cebecauer Marek; Guillaume Philippe; Hozák Pavel; Mark Silke; Everett Helen; Schneider Pascal; Luescher Immanuel F
Soluble MHC-peptide complexes induce rapid death of CD8+ CTL.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(11):6809-19.
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2005: Schneider Pascal
The role of APRIL and BAFF in lymphocyte activation.
Current opinion in immunology 2005;17(3):282-9.
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2005: Ingold Karine; Zumsteg Adrian; Tardivel Aubry; Huard Bertrand; Steiner Quynh-Giao; Cachero Teresa G; Qiang Fang; Gorelik Leonid; Kalled Susan L; Acha-Orbea Hans; Rennert Paul D; Tschopp Jürg; Schneider Pascal
Identification of proteoglycans as the APRIL-specific binding partners.
The Journal of experimental medicine 2005;201(9):1375-83.
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2004: Tardivel Aubry; Tinel Antoine; Lens Susanne; Steiner Quynh-Giao; Sauberli Estelle; Wilson Anne; Mackay Fabienne; Rolink Antonius G; Beermann Friedrich; Tschopp Jürg; Schneider Pascal
The anti-apoptotic factor Bcl-2 can functionally substitute for the B cell survival but not for the marginal zone B cell differentiation activity of BAFF.
European journal of immunology 2004;34(2):509-18.
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2004: Batten Marcel; Fletcher Carrie; Ng Lai Guan; Groom Joanna; Wheway Julie; Laâbi Yacine; Xin Xiaoguan; Schneider Pascal; Tschopp Jurg; Mackay Charles R; Mackay Fabienne
TNF deficiency fails to protect BAFF transgenic mice against autoimmunity and reveals a predisposition to B cell lymphoma.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(2):812-22.
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2004: Schneider Kirsten; Kothlow Sonja; Schneider Pascal; Tardivel Aubry; Göbel Thomas; Kaspers Bernd; Staeheli Peter
Chicken BAFF--a highly conserved cytokine that mediates B cell survival.
International immunology 2004;16(1):139-48.
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2003: Schneider Pascal; Tschopp Jürg
BAFF and the regulation of B cell survival.
Immunology letters 2003;88(1):57-62.
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2003: Gaide Olivier; Schneider Pascal
Permanent correction of an inherited ectodermal dysplasia with recombinant EDA.
Nature medicine 2003;9(5):614-8.
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2003: Brunetti Craig R; Paulose-Murphy Mini; Singh Rajkumari; Qin Jing; Barrett John W; Tardivel Aubry; Schneider Pascal; Essani Karim; McFadden Grant
A secreted high-affinity inhibitor of human TNF from Tanapox virus.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(8):4831-6.
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2003: Holler Nils; Tardivel Aubry; Kovacsovics-Bankowski Magdalena; Hertig Sylvie; Gaide Olivier; Martinon Fabio; Tinel Antoine; Deperthes David; Calderara Silvio; Schulthess Therese; Engel Jürgen; Schneider Pascal; Tschopp Jürg
Two adjacent trimeric Fas ligands are required for Fas signaling and formation of a death-inducing signaling complex.
Molecular and cellular biology 2003;23(4):1428-40.
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2003: Schneider Pascal; Olson Dian; Tardivel Aubry; Browning Beth; Lugovskoy Alexey; Gong DaHai; Dobles Max; Hertig Sylvie; Hofmann Kay; Van Vlijmen Herman; Hsu Yen-Ming; Burkly Linda C; Tschopp Jurg; Zheng Timothy S
Identification of a new murine tumor necrosis factor receptor locus that contains two novel murine receptors for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL).
The Journal of biological chemistry 2003;278(7):5444-54.
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2002: Strik Merel C; Bladergroen Bellinda A; Wouters Dorine; Kisiel Walter; Hooijberg Jan Hendrik; Verlaan Angelique R; Hordijk Peter L; Schneider Pascal; Hack C Erik; Kummer J Alain
Distribution of the human intracellular serpin protease inhibitor 8 in human tissues.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2002;50(11):1443-54.
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2002: Micheau Olivier; Thome Margot; Schneider Pascal; Holler Nils; Tschopp Jürg; Nicholson Donald W; Briand Christophe; Grütter Markus G
The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex.
The Journal of biological chemistry 2002;277(47):45162-71.
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2002: Lowin-Kropf Bente; Kunz Béatrice; Schneider Pascal; Held Werner
A role for the src family kinase Fyn in NK cell activation and the formation of the repertoire of Ly49 receptors.
European journal of immunology 2002;32(3):773-82.
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2002: Bodmer Jean-Luc; Schneider Pascal; Tschopp Jürg
The molecular architecture of the TNF superfamily.
Trends in biochemical sciences 2002;27(1):19-26.
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2002: Groom Joanna; Kalled Susan L; Cutler Anne H; Olson Carl; Woodcock Stephen A; Schneider Pascal; Tschopp Jurg; Cachero Teresa G; Batten Marcel; Wheway Julie; Mauri Davide; Cavill Dana; Gordon Tom P; Mackay Charles R; Mackay Fabienne
Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjögren's syndrome.
The Journal of clinical investigation 2002;109(1):59-68.
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2001: Schneider P; Takatsuka H; Wilson A; Mackay F; Tardivel A; Lens S; Cachero T G; Finke D; Beermann F; Tschopp J
Maturation of marginal zone and follicular B cells requires B cell activating factor of the tumor necrosis factor family and is independent of B cell maturation antigen.
The Journal of experimental medicine 2001;194(11):1691-7.
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2001: Thompson J S; Bixler S A; Qian F; Vora K; Scott M L; Cachero T G; Hession C; Schneider P; Sizing I D; Mullen C; Strauch K; Zafari M; Benjamin C D; Tschopp J; Browning J L; Ambrose C
BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF.
Science (New York, N.Y.) 2001;293(5537):2108-11.
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2001: Schneider P; Street S L; Gaide O; Hertig S; Tardivel A; Tschopp J; Runkel L; Alevizopoulos K; Ferguson B M; Zonana J
Mutations leading to X-linked hypohidrotic ectodermal dysplasia affect three major functional domains in the tumor necrosis factor family member ectodysplasin-A.
The Journal of biological chemistry 2001;276(22):18819-27.
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2001: Werner-Favre C; Bovia F; Schneider P; Holler N; Barnet M; Kindler V; Tschopp J; Zubler R H
IgG subclass switch capacity is low in switched and in IgM-only, but high in IgD+IgM+, post-germinal center (CD27+) human B cells.
European journal of immunology 2001;31(1):243-9.
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2000: Rennert P; Schneider P; Cachero T G; Thompson J; Trabach L; Hertig S; Holler N; Qian F; Mullen C; Strauch K; Browning J L; Ambrose C; Tschopp J
A soluble form of B cell maturation antigen, a receptor for the tumor necrosis factor family member APRIL, inhibits tumor cell growth.
The Journal of experimental medicine 2000;192(11):1677-84.
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2000: Holler N; Zaru R; Micheau O; Thome M; Attinger A; Valitutti S; Bodmer J L; Schneider P; Seed B; Tschopp J
Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule.
Nature immunology 2000;1(6):489-95.
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2000: Batten M; Groom J; Cachero T G; Qian F; Schneider P; Tschopp J; Browning J L; Mackay F
BAFF mediates survival of peripheral immature B lymphocytes.
The Journal of experimental medicine 2000;192(10):1453-66.
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2000: Tucker A S; Headon D J; Schneider P; Ferguson B M; Overbeek P; Tschopp J; Sharpe P T
Edar/Eda interactions regulate enamel knot formation in tooth morphogenesis.
Development (Cambridge, England) 2000;127(21):4691-700.
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2000: Rochat-Steiner V; Becker K; Micheau O; Schneider P; Burns K; Tschopp J
FIST/HIPK3: a Fas/FADD-interacting serine/threonine kinase that induces FADD phosphorylation and inhibits fas-mediated Jun NH(2)-terminal kinase activation.
The Journal of experimental medicine 2000;192(8):1165-74.
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2000: Mühlenbeck F; Schneider P; Bodmer J L; Schwenzer R; Hauser A; Schubert G; Scheurich P; Moosmayer D; Tschopp J; Wajant H
The tumor necrosis factor-related apoptosis-inducing ligand receptors TRAIL-R1 and TRAIL-R2 have distinct cross-linking requirements for initiation of apoptosis and are non-redundant in JNK activation.
The Journal of biological chemistry 2000;275(41):32208-13.
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2000: Thompson J S; Schneider P; Kalled S L; Wang L; Lefevre E A; Cachero T G; MacKay F; Bixler S A; Zafari M; Liu Z Y; Woodcock S A; Qian F; Batten M; Madry C; Richard Y; Benjamin C D; Browning J L; Tsapis A; Tschopp J; Ambrose C
BAFF binds to the tumor necrosis factor receptor-like molecule B cell maturation antigen and is important for maintaining the peripheral B cell population.
The Journal of experimental medicine 2000;192(1):129-35.
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2000: Bodmer J L; Meier P; Tschopp J; Schneider P
Cysteine 230 is essential for the structure and activity of the cytotoxic ligand TRAIL.
The Journal of biological chemistry 2000;275(27):20632-7.
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2000: Bodmer J L; Holler N; Reynard S; Vinciguerra P; Schneider P; Juo P; Blenis J; Tschopp J
TRAIL receptor-2 signals apoptosis through FADD and caspase-8.
Nature cell biology 2000;2(4):241-3.
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2000: Holler N; Kataoka T; Bodmer J L; Romero P; Romero J; Deperthes D; Engel J; Tschopp J; Schneider P
Development of improved soluble inhibitors of FasL and CD40L based on oligomerized receptors.
Journal of immunological methods 2000;237(1-2):159-73.
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2000: Schneider P; Tschopp J
Modulation of death receptor signalling.
Symposia of the Society for Experimental Biology 2000;52():31-42.
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2000: Schneider P
Production of recombinant TRAIL and TRAIL receptor: Fc chimeric proteins.
Methods in enzymology 2000;322():325-45.
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1999: Mackay F; Woodcock S A; Lawton P; Ambrose C; Baetscher M; Schneider P; Tschopp J; Browning J L
Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations.
The Journal of experimental medicine 1999;190(11):1697-710.
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1999: Corradin S; Ransijn A; Corradin G; Roggero M A; Schmitz A A; Schneider P; Mauël J; Vergères G
MARCKS-related protein (MRP) is a substrate for the Leishmania major surface protease leishmanolysin (gp63).
The Journal of biological chemistry 1999;274(36):25411-8.
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1999: Schneider P; Schwenzer R; Haas E; Mühlenbeck F; Schubert G; Scheurich P; Tschopp J; Wajant H
TWEAK can induce cell death via endogenous TNF and TNF receptor 1.
European journal of immunology 1999;29(6):1785-92.
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1999: Schneider P; MacKay F; Steiner V; Hofmann K; Bodmer J L; Holler N; Ambrose C; Lawton P; Bixler S; Acha-Orbea H; Valmori D; Romero P; Werner-Favre C; Zubler R H; Browning J L; Tschopp J
BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth.
The Journal of experimental medicine 1999;189(11):1747-56.
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1999: Thome M; Martinon F; Hofmann K; Rubio V; Steiner V; Schneider P; Mattmann C; Tschopp J
Equine herpesvirus-2 E10 gene product, but not its cellular homologue, activates NF-kappaB transcription factor and c-Jun N-terminal kinase.
The Journal of biological chemistry 1999;274(15):9962-8.
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1998: Kataoka T; Schröter M; Hahne M; Schneider P; Irmler M; Thome M; Froelich C J; Tschopp J
FLIP prevents apoptosis induced by death receptors but not by perforin/granzyme B, chemotherapeutic drugs, and gamma irradiation.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(8):3936-42.
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1998: Hahne M; Kataoka T; Schröter M; Hofmann K; Irmler M; Bodmer J L; Schneider P; Bornand T; Holler N; French L E; Sordat B; Rimoldi D; Tschopp J
APRIL, a new ligand of the tumor necrosis factor family, stimulates tumor cell growth.
The Journal of experimental medicine 1998;188(6):1185-90.
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1998: Burns K; Martinon F; Esslinger C; Pahl H; Schneider P; Bodmer J L; Di Marco F; French L; Tschopp J
MyD88, an adapter protein involved in interleukin-1 signaling.
The Journal of biological chemistry 1998;273(20):12203-9.
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1998: Schneider P; Holler N; Bodmer J L; Hahne M; Frei K; Fontana A; Tschopp J
Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity.
The Journal of experimental medicine 1998;187(8):1205-13.
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1997: Schneider P; Thome M; Burns K; Bodmer J L; Hofmann K; Kataoka T; Holler N; Tschopp J
TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappaB.
Immunity 1997;7(6):831-6.
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1997: Schneider P; Bodmer J L; Thome M; Hofmann K; Holler N; Tschopp J
Characterization of two receptors for TRAIL.
FEBS letters 1997;416(3):329-34.
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1997: Becker K; Schneider P; Hofmann K; Mattmann C; Tschopp J
Interaction of Fas(Apo-1/CD95) with proteins implicated in the ubiquitination pathway.
FEBS letters 1997;412(1):102-6.
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1997: Schneider P; Bodmer J L; Holler N; Mattmann C; Scuderi P; Terskikh A; Peitsch M C; Tschopp J
Characterization of Fas (Apo-1, CD95)-Fas ligand interaction.
The Journal of biological chemistry 1997;272(30):18827-33.
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1997: Irmler M; Thome M; Hahne M; Schneider P; Hofmann K; Steiner V; Bodmer J L; Schröter M; Burns K; Mattmann C; Rimoldi D; French L E; Tschopp J
Inhibition of death receptor signals by cellular FLIP.
Nature 1997;388(6638):190-5.
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1997: Thome M; Schneider P; Hofmann K; Fickenscher H; Meinl E; Neipel F; Mattmann C; Burns K; Bodmer J L; Schröter M; Scaffidi C; Krammer P H; Peter M E; Tschopp J
Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors.
Nature 1997;386(6624):517-21.
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1997: Bodmer J L; Burns K; Schneider P; Hofmann K; Steiner V; Thome M; Bornand T; Hahne M; Schröter M; Becker K; Wilson A; French L E; Browning J L; MacDonald H R; Tschopp J
TRAMP, a novel apoptosis-mediating receptor with sequence homology to tumor necrosis factor receptor 1 and Fas(Apo-1/CD95).
Immunity 1997;6(1):79-88.
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1996: Hahne M; Rimoldi D; Schröter M; Romero P; Schreier M; French L E; Schneider P; Bornand T; Fontana A; Lienard D; Cerottini J; Tschopp J
Melanoma cell expression of Fas(Apo-1/CD95) ligand: implications for tumor immune escape.
Science (New York, N.Y.) 1996;274(5291):1363-6.
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1995: Buchmüller-Rouiller Y; Corrandin S B; Smith J; Schneider P; Ransijn A; Jongeneel C V; Mauël J
Role of glutathione in macrophage activation: effect of cellular glutathione depletion on nitrite production and leishmanicidal activity.
Cellular immunology 1995;164(1):73-80.
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1995: Bouvier J; Schneider P; Etges R
Leishmanolysin: surface metalloproteinase of Leishmania.
Methods in enzymology 1995;248():614-33.
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1995: Schneider P; Ferguson M A
Microscale analysis of glycosylphosphatidylinositol structures.
Methods in enzymology 1995;250():614-30.
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1993: Schneider P; Glaser T A
Characterisation of two soluble metalloexopeptidases in the protozoan parasite Leishmania major.
Molecular and biochemical parasitology 1993;62(2):223-31.
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1993: Schneider P; Glaser T A
Characterization of a surface metalloprotease from Herpetomonas samuelpessoai and comparison with Leishmania major promastigote surface protease.
Molecular and biochemical parasitology 1993;58(2):277-82.
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1992: Schneider P; Rosat J P; Bouvier J; Louis J; Bordier C
Leishmania major: differential regulation of the surface metalloprotease in amastigote and promastigote stages.
Experimental parasitology 1992;75(2):196-206.
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1992: Buchmüller-Rouiller Y; Schneider P; Betz-Corradin S; Smith J; Mauël J
3-amino-1,2,4-triazole inhibits macrophage NO synthase.
Biochemical and biophysical research communications 1992;183(1):150-5.
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1992: Schneider P; Bordier C; Etges R
Membrane proteins and enzymes of Leishmania.
Sub-cellular biochemistry 1992;18():39-72.
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1990: Bouvier J; Schneider P; Etges R; Bordier C
Peptide substrate specificity of the membrane-bound metalloprotease of Leishmania.
Biochemistry 1990;29(43):10113-9.
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1990: Schneider P; Ferguson M A; McConville M J; Mehlert A; Homans S W; Bordier C
Structure of the glycosyl-phosphatidylinositol membrane anchor of the Leishmania major promastigote surface protease.
The Journal of biological chemistry 1990;265(28):16955-64.
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