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James Scholey

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K Koulajian; G C Liu; J N Patterson; James W Scholey; C Tang; T Desai; J El-Benna; A Ivovic; Jamie W Joseph; A Giacca
NADPH oxidase inhibition prevents beta cell dysfunction induced by prolonged elevation of oleate in rodents.
R Har; Vesta Lai; F H Mahmud; H N Reich; James W Scholey; Etienne Sochett; D Daneman; R Dekker; Y Elia; M L Fritzler; David Z I Cherney
The effect of renal hyperfiltration on urinary inflammatory cytokines/chemokines in patients with uncomplicated type 1 diabetes mellitus.
David Z I Cherney; James W Scholey; Etienne Sochett
Sex differences in renal responses to hyperglycemia, L-arginine, and L-NMMA in humans with uncomplicated type 1 diabetes.

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2013: K Koulajian; G C Liu; J N Patterson; James W Scholey; C Tang; T Desai; J El-Benna; A Ivovic; Jamie W Joseph; A Giacca
NADPH oxidase inhibition prevents beta cell dysfunction induced by prolonged elevation of oleate in rodents.
Diabetologia 2013;56(5):1078-87.
2013: R Har; Vesta Lai; F H Mahmud; H N Reich; James W Scholey; Etienne Sochett; D Daneman; R Dekker; Y Elia; M L Fritzler; David Z I Cherney
The effect of renal hyperfiltration on urinary inflammatory cytokines/chemokines in patients with uncomplicated type 1 diabetes mellitus.
Diabetologia 2013;56(5):1166-73.
2013: David Z I Cherney; James W Scholey; Etienne Sochett
Sex differences in renal responses to hyperglycemia, L-arginine, and L-NMMA in humans with uncomplicated type 1 diabetes.
Diabetes care 2013;36(5):1290-6.
2012: Ratnadeep Basu; Subhash K Das; Dong Fan; Rohan John; Jiwon Lee; George C Liu; Gavin Y Oudit; Vaibhav B Patel; James W Scholey; Zuocheng Wang; Zamaneh Kassiri
Loss of TIMP3 selectively exacerbates diabetic nephropathy.
American journal of physiology. Renal physiology 2012;303(9):F1341-52.
2012: David Z I Cherney; Ronnie Har; Shan Jiang; Vesta Lai; James W Scholey; Etienne Sochett; Heather N Reich
The effect of direct renin inhibition alone and in combination with ACE inhibition on endothelial function, arterial stiffness, and renal function in type 1 diabetes.
Diabetes care 2012;35(11):2324-30.
2012: David Z I Cherney; Ronnie Har; Richard L Hébert; Shan Jiang; Vesta Lai; Rania Nasrallah; Heather N Reich; James W Scholey; Etienne Sochett
Hyperfiltration and effect of nitric oxide inhibition on renal and endothelial function in humans with uncomplicated type 1 diabetes mellitus.
American journal of physiology. Regulatory, integrative and comparative physiology 2012;303(7):R710-8.
2012: G C Liu; Gavin Y Oudit; H N Reich; F Fang; A Giacca; Andrew Herzenberg; R John; K Koulajian; L Lam; S Yang; J Zhou; James W Scholey
Deletion of p47phox attenuates the progression of diabetic nephropathy and reduces the severity of diabetes in the Akita mouse.
Diabetologia 2012;55(9):2522-32.
2012: George C Liu; Gavin Y Oudit; Fei Fang; Joyce Zhou; James W Scholey
Angiotensin-(1-7)-induced activation of ERK1/2 is cAMP/protein kinase A-dependent in glomerular mesangial cells.
American journal of physiology. Renal physiology 2012;302(6):F784-90.
2012: Ana Konvalinka; James W Scholey; Eleftherios P Diamandis
Searching for new biomarkers of renal diseases through proteomics.
Clinical chemistry 2012;58(2):353-65.
2011: Sreedhar Bodiga; Danny Guo; Steven M Holland; Zamaneh Kassiri; George C Liu; Jennifer Lo; Josef M Penninger; James W Scholey; Wang Wang; Jiu-Chang Zhong; Ratnadeep Basu; Gavin Y Oudit
Enhanced susceptibility to biomechanical stress in ACE2 null mice is prevented by loss of the p47(phox) NADPH oxidase subunit.
Cardiovascular research 2011;91(1):151-61.
2011: Heather N Reich; Dafna D Gladman; Murray B Urowitz; Joanne M Bargman; Michelle A Hladunewich; Wendy Lou; Steve C P Fan; Jiandong Su; Andrew M Herzenberg; Daniel C Cattran; Joan Wither; Carol Landolt-Marticorena; James W Scholey; Paul R Fortin
Persistent proteinuria and dyslipidemia increase the risk of progressive chronic kidney disease in lupus erythematosus.
Kidney international 2011;79(8):914-20.
2011: JiuChang Zhong; Danny Guo; Christopher B Chen; Wang Wang; Manfred Schuster; Hans Loibner; Josef M Penninger; James W Scholey; Zamaneh Kassiri; Gavin Y Oudit
Prevention of angiotensin II-mediated renal oxidative stress, inflammation, and fibrosis by angiotensin-converting enzyme 2.
Hypertension 2011;57(2):314-22.
2011: David Z I Cherney; James W Scholey; Etienne Sochett; Timothy J Bradley; Heather N Reich
The acute effect of clamped hyperglycemia on the urinary excretion of inflammatory cytokines/chemokines in uncomplicated type 1 diabetes: a pilot study.
Diabetes care 2011;34(1):177-80.
2010: David Z I Cherney; Heather N Reich; Judith A Miller; Vesta Lai; Bernard Zinman; Maria G Dekker; Timothy J Bradley; James W Scholey; Etienne Sochett
Age is a determinant of acute hemodynamic responses to hyperglycemia and angiotensin II in humans with uncomplicated type 1 diabetes mellitus.
American journal of physiology. Regulatory, integrative and comparative physiology 2010;299(1):R206-14.
2010: Gavin Y Oudit; George C Liu; Jiuchang Zhong; Ratnadeep Basu; Fung L Chow; Joyce Zhou; Hans Loibner; Evelyne Janzek; Manfred Schuster; Josef M Penninger; Andrew M Herzenberg; Zamaneh Kassiri; James W Scholey
Human recombinant ACE2 reduces the progression of diabetic nephropathy.
Diabetes 2010;59(2):529-38.
2010: Leighton R James; Catherine Le; James W Scholey
Influence of glucosamine on glomerular mesangial cell turnover: implications for hyperglycemia and hexosamine pathway flux.
American journal of physiology. Endocrinology and metabolism 2010;298(2):E210-21.
2010: David Z I Cherney; Vesta Lai; James W Scholey; Judith A Miller; Bernard Zinman; Heather N Reich
Effect of direct renin inhibition on renal hemodynamic function, arterial stiffness, and endothelial function in humans with uncomplicated type 1 diabetes: a pilot study.
Diabetes care 2010;33(2):361-5.
2010: Heather N Reich; David Tritchler; Daniel C Cattran; Andrew M Herzenberg; Felix Eichinger; Anissa Boucherot; Anna Henger; Celine C Berthier; Viji Nair; Clemens D Cohen; James W Scholey; Matthias Kretzler
A molecular signature of proteinuria in glomerulonephritis.
PloS one 2010;5(10):e13451.
2009: David Z I Cherney; James W Scholey; Joyce Zhou; Joseph Zimpelmann; Christopher Kennedy; Kevin D Burns; Vesta Lai; Judith A Miller
Endothelial nitric oxide synthase gene polymorphisms and the renal hemodynamic response to L-arginine.
Kidney international 2009;75(3):327-32.
2009: David Z I Cherney; Ana Konvalinka; Bernard Zinman; Eleftherios P Diamandis; Anton Soosaipillai; Heather Reich; Joanne Lorraine; Vesta Lai; James W Scholey; Judith A Miller
Effect of protein kinase Cbeta inhibition on renal hemodynamic function and urinary biomarkers in humans with type 1 diabetes: a pilot study.
Diabetes care 2009;32(1):91-3.
2008: David Z I Cherney; James W Scholey; Judith A Miller
Insights into the regulation of renal hemodynamic function in diabetic mellitus.
Current diabetes reviews 2008;4(4):280-90.
2008: Daniel C Cattran; Heather Reich; Heather J Beanlands; Judith A Miller; James W Scholey; Stéphan Troyanov
The impact of sex in primary glomerulonephritis.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2008;23(7):2247-53.
2008: Gavin Y Oudit; Zamaneh Kassiri; Joyce Zhou; Qiao C Liu; Peter P Liu; Peter H Backx; Fayez Dawood; Michael A Crackower; James W Scholey; Josef M Penninger
Loss of PTEN attenuates the development of pathological hypertrophy and heart failure in response to biomechanical stress.
Cardiovascular research 2008;78(3):505-14.
2008: David Z I Cherney; Judith A Miller; James W Scholey; Timothy J Bradley; Cameron Slorach; Jaqueline R Curtis; Maria G Dekker; Rania Nasrallah; Richard L Hébert; Etienne Sochett
The effect of cyclooxygenase-2 inhibition on renal hemodynamic function in humans with type 1 diabetes.
Diabetes 2008;57(3):688-95.
2007: Heather Reich; Stéphan Troyanov; James W Scholey; Daniel C Cattran
Remission of proteinuria improves prognosis in IgA nephropathy.
Journal of the American Society of Nephrology : JASN 2007;18(12):3177-83.
2007: David Z I Cherney; James W Scholey; Daniel C Cattran; Amrit K Kang; Joseph Zimpelmann; C Kennedy; Vesta Lai; Kevin D Burns; Judith A Miller
The effect of oral contraceptives on the nitric oxide system and renal function.
American journal of physiology. Renal physiology 2007;293(5):F1539-44.
2007: Denise W Wong; Gavin Y Oudit; Heather Reich; Zamaneh Kassiri; Joyce Zhou; Qiao C Liu; Peter H Backx; Josef M Penninger; Andrew Herzenberg; James W Scholey
Loss of angiotensin-converting enzyme-2 (Ace2) accelerates diabetic kidney injury.
The American journal of pathology 2007;171(2):438-51.
2007: Gavin Y Oudit; Zamaneh Kassiri; Mikin P Patel; Mark Chappell; Jagdish Butany; Peter H Backx; Robert G Tsushima; James W Scholey; Rama Khokha; Josef M Penninger
Angiotensin II-mediated oxidative stress and inflammation mediate the age-dependent cardiomyopathy in ACE2 null mice.
Cardiovascular research 2007;75(1):29-39.
2007: suresh shastry; Alistair J Ingram; James W Scholey; Leighton R James
Homocysteine induces mesangial cell apoptosis via activation of p38-mitogen-activated protein kinase.
Kidney international 2007;71(4):304-11.
2006: Judith A Miller; David Z I Cherney; John A Duncan; Vesta Lai; Kevin D Burns; Christopher R J Kennedy; Joseph Zimpelmann; Wei Gao; Daniel C Cattran; James W Scholey
Gender differences in the renal response to renin-angiotensin system blockade.
Journal of the American Society of Nephrology : JASN 2006;17(9):2554-60.
2006: Gavin Y Oudit; Andrew Herzenberg; Zamaneh Kassiri; Denise Wong; Heather Reich; Rama Khokha; Michael A Crackower; Peter H Backx; Josef M Penninger; James W Scholey
Loss of angiotensin-converting enzyme-2 leads to the late development of angiotensin II-dependent glomerulosclerosis.
The American journal of pathology 2006;168(6):1808-20.
2006: Etienne Sochett; David Z I Cherney; Jacqueline R Curtis; Maria G Dekker; James W Scholey; Judith A Miller
Impact of renin angiotensin system modulation on the hyperfiltration state in type 1 diabetes.
Journal of the American Society of Nephrology : JASN 2006;17(6):1703-9.
2005: Andrea Page; Heather Reich; Joyce Zhou; Vesta Lai; Daniel C Cattran; James W Scholey; Judith A Miller
Endothelial nitric oxide synthase gene/gender interactions and the renal hemodynamic response to angiotensin II.
Journal of the American Society of Nephrology : JASN 2005;16(10):3053-60.
2005: Heather Reich; David Tritchler; Andrew Herzenberg; Zamaneh Kassiri; Xiaohua Zhou; Wei Gao; James W Scholey
Albumin activates ERK via EGF receptor in human renal epithelial cells.
Journal of the American Society of Nephrology : JASN 2005;16(5):1266-78.
2005: Stéphan Troyanov; Catherine A Wall; Judith A Miller; James W Scholey; Daniel C Cattran
Focal and segmental glomerulosclerosis: definition and relevance of a partial remission.
Journal of the American Society of Nephrology : JASN 2005;16(4):1061-8.
2004: Dale M Needham; Kathryn A Shufelt; George Tomlinson; James W Scholey; Gary E Newton
Troponin I and T levels in renal failure patients without acute coronary syndrome: a systematic review of the literature.
The Canadian journal of cardiology 2004;20(12):1212-8.
2004: Xianghong Zhu; Andrew Herzenberg; Mohammad Eskandarian; Graham F Maguire; James W Scholey; Philip W Connelly; Dominic S Ng
A novel in vivo lecithin-cholesterol acyltransferase (LCAT)-deficient mouse expressing predominantly LpX is associated with spontaneous glomerulopathy.
The American journal of pathology 2004;165(4):1269-78.
2004: Stéphan Troyanov; Catherine A Wall; Judith A Miller; James W Scholey; Daniel C Cattran
Idiopathic membranous nephropathy: definition and relevance of a partial remission.
Kidney international 2004;66(3):1199-205.
2004: Alistair J Ingram; Joan C Krepinsky; Leighton James; Richard C Austin; Damu Tang; Anne Marie Salapatek; Kerri Thai; James W Scholey
Activation of mesangial cell MAPK in response to homocysteine.
Kidney international 2004;66(2):733-45.
2004: Sofia B Ahmed; Amrit K Kang; Kevin D Burns; Christopher R J Kennedy; Vesta Lai; Daniel C Cattran; James W Scholey; Judith A Miller
Effects of oral contraceptive use on the renal and systemic vascular response to angiotensin II infusion.
Journal of the American Society of Nephrology : JASN 2004;15(3):780-6.
2004: Ian Bookman; James W Scholey; Sarbjit V Jassal; Ginette Lajoie; Andrew Herzenberg
Necrotizing glomerulonephritis caused by Bartonella henselae endocarditis.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2004;43(2):e25-30.
2004: Judith A Miller; James W Scholey
The impact of renin-angiotensin system polymorphisms on physiological and pathophysiological processes in humans.
Current opinion in nephrology and hypertension 2004;13(1):101-6.
2003: Joan C Krepinsky; Alistair J Ingram; Damu Tang; Dongcheng Wu; Lieqi Liu; James W Scholey
Nitric oxide inhibits stretch-induced MAPK activation in mesangial cells through RhoA inactivation.
Journal of the American Society of Nephrology : JASN 2003;14(11):2790-800.
2003: James W Scholey
Angiotensin II and the glomerulus: focus on diabetic kidney disease.
Current hypertension reports 2003;5(2):172-80.
2003: Heather Reich; John A Duncan; Jordan Weinstein; Daniel C Cattran; James W Scholey; Judith A Miller
Interactions between gender and the angiotensin type 1 receptor gene polymorphism.
Kidney international 2003;63(4):1443-9.
2002: Leighton R James; Damu Tang; Alistair J Ingram; Hao Ly; Kerri Thai; Lu Cai; James W Scholey
Flux through the hexosamine pathway is a determinant of nuclear factor kappaB- dependent promoter activation.
Diabetes 2002;51(4):1146-56.
2002: Joan C Krepinsky; Alistair J Ingram; Leighton James; Hao Ly; Kerri Thai; Daniel C Cattran; Judith A Miller; James W Scholey
17beta -Estradiol modulates mechanical strain-induced MAPK activation in mesangial cells.
The Journal of biological chemistry 2002;277(11):9387-94.
2002: Mala Chidambaram; John A Duncan; Vesta Lai; Daniel C Cattran; John S Floras; James W Scholey; Judith A Miller
Variation in the renin angiotensin system throughout the normal menstrual cycle.
Journal of the American Society of Nephrology : JASN 2002;13(2):446-52.
2001: Leighton R James; Alistair J Ingram; Hao Ly; Kerri Thai; Lu Cai; James W Scholey
Angiotensin II activates the GFAT promoter in mesangial cells.
American journal of physiology. Renal physiology 2001;281(1):F151-62.
2001: Amrit K Kang; John A Duncan; Daniel C Cattran; John S Floras; Vesta Lai; James W Scholey; Judith A Miller
Effect of oral contraceptives on the renin angiotensin system and renal function.
American journal of physiology. Regulatory, integrative and comparative physiology 2001;280(3):R807-13.
2001: John A Duncan; James W Scholey; Judith A Miller
Angiotensin II type 1 receptor gene polymorphisms in humans: physiology and pathophysiology of the genotypes.
Current opinion in nephrology and hypertension 2001;10(1):111-6.
2000: Alistair J Ingram; Leighton James; Lu Cai; Kerri Thai; Hao Ly; James W Scholey
NO inhibits stretch-induced MAPK activity by cytoskeletal disruption.
The Journal of biological chemistry 2000;275(51):40301-6.
2000: MJ Kang; Alistair J Ingram; Hao Ly; Kerri Thai; James W Scholey
Effects of diabetes and hypertension on glomerular transforming growth factor-beta receptor expression.
Kidney international 2000;58(4):1677-85.
2000: Alistair J Ingram; Leighton James; Hao Ly; Kerri Thai; James W Scholey
Stretch activation of jun N-terminal kinase/stress-activated protein kinase in mesangial cells.
Kidney international 2000;58(4):1431-9.
2000: Leighton R James; I George Fantus; Howard Goldberg; Hao Ly; James W Scholey
Overexpression of GFAT activates PAI-1 promoter in mesangial cells.
American journal of physiology. Renal physiology 2000;279(4):F718-27.
2000: John A Dlugosz; Snezana Munk; Jovana Kapor; Howard J Goldberg; I George Fantus; James W Scholey; Catharine I Whiteside
Stretch-induced mesangial cell ERK1/ERK2 activation is enhanced in high glucose by decreased dephosphorylation.
American journal of physiology. Renal physiology 2000;279(4):F688-97.
2000: Alistair J Ingram; Leighton James; Hao Ly; Kerri Thai; Lu Cai; James W Scholey
Nitric oxide modulates stretch activation of mitogen-activated protein kinases in mesangial cells.
Kidney international 2000;58(3):1067-77.
2000: Judith A Miller; Kerri Thai; James W Scholey
Angiotensin II type 1 receptor gene polymorphism and the response to hyperglycemia in early type 1 diabetes.
Diabetes 2000;49(9):1585-9.
2000: Alistair J Ingram; Leighton James; Kerri Thai; Hao Ly; Lu Cai; James W Scholey
Nitric oxide modulates mechanical strain-induced activation of p38 MAPK in mesangial cells.
American journal of physiology. Renal physiology 2000;279(2):F243-51.
2000: X Wu; James W Scholey; H Sonnenberg; Luis G Melo
Renal vascular morphology and haemodynamics in Dahl salt-sensitive rats on high salt-low potassium diet: neural and genetic influences.
Journal of hypertension 2000;18(6):783-93.
2000: Alistair J Ingram; James W Scholey
Stress-responsive signal transduction mechanisms in glomerular cells.
Current opinion in nephrology and hypertension 2000;9(1):49-55.
1999: Judith A Miller; Kerri Thai; James W Scholey
Angiotensin II type 1 receptor gene polymorphism predicts response to losartan and angiotensin II.
Kidney international 1999;56(6):2173-80.
1999: Alistair J Ingram; Hao Ly; Kerri Thai; MJ Kang; James W Scholey
Mesangial cell signaling cascades in response to mechanical strain and glucose.
Kidney international 1999;56(5):1721-8.
1999: MJ Kang; X Wu; Hao Ly; Kerri Thai; James W Scholey
Effect of glucose on stress-activated protein kinase activity in mesangial cells and diabetic glomeruli.
Kidney international 1999;55(6):2203-14.
1999: Alistair J Ingram; Hao Ly; Kerri Thai; M Kang; James W Scholey
Activation of mesangial cell signaling cascades in response to mechanical strain.
Kidney international 1999;55(2):476-85.
1997: Alistair J Ingram; James W Scholey
Protooncogene expression and diabetic kidney injury.
Kidney international. Supplement 1997;60():S70-6.
1997: S J Shankland; Paul A Hamel; James W Scholey
Cyclin and cyclin-dependent kinase expression in the remnant glomerulus.
Journal of the American Society of Nephrology : JASN 1997;8(3):368-75.
1997: Judith A Miller; James W Scholey; Kerri Thai; Y P Pei
Angiotensin converting enzyme gene polymorphism and renal hemodynamic function in early diabetes.
Kidney international 1997;51(1):119-24.
1996: Alistair J Ingram; A Parbtani; William F Clark; E Spanner; Murray W Huff; D J Philbrick; Bruce J Holub; James W Scholey
Dietary alteration of dihomogamma-linolenic acid/arachidonic acid ratio in a rat 5/6-renal-ablation model. The Nutrition & Kidney Disease Research Group.
Journal of the American Society of Nephrology : JASN 1996;7(7):1024-31.
1996: G F McDermott; Alistair J Ingram; James W Scholey; J L Kirkland; Catharine I Whiteside
Glomerular dysfunction in the aging Fischer 344 rat is associated with excessive growth and normal mesangial cell function.
The journals of gerontology. Series A, Biological sciences and medical sciences 1996;51(2):M80-5.
1996: X Wu; James W Scholey; H Sonnenberg
Renal vascular morphology in male Dahl rats on high-salt diet: effect of potassium.
Journal of the American Society of Nephrology : JASN 1996;7(2):338-44.
1996: S J Shankland; Hao Ly; Kerri Thai; James W Scholey
Glomerular expression of tissue inhibitor of metalloproteinase (TIMP-1) in normal and diabetic rats.
Journal of the American Society of Nephrology : JASN 1996;7(1):97-104.
1995: Alistair J Ingram; A Parbtani; Kerri Thai; Hao Ly; S J Shankland; G Morrissey; James W Scholey
Dietary supplementation with L-arginine limits cell proliferation in the remnant glomerulus.
Kidney international 1995;48(6):1857-65.
1995: S J Shankland; James W Scholey
Expression of growth-related protooncogenes during diabetic renal hypertrophy.
Kidney international 1995;47(3):782-8.
1995: James W Scholey; D E Mills
Dietary fatty acids and the glomerular hemodynamic response to cyclosporine in borderline hypertensive rats.
Kidney international 1995;47(2):611-7.
1994: S J Shankland; Hao Ly; Kerri Thai; James W Scholey
Increased glomerular capillary pressure alters glomerular cytokine expression.
Circulation research 1994;75(5):844-53.
1994: S J Shankland; James W Scholey; Hao Ly; Kerri Thai
Expression of transforming growth factor-beta 1 during diabetic renal hypertrophy.
Kidney international 1994;46(2):430-42.