FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Martin Scholtz

Research Profile

Disorders

Protein Denaturation

Occupations

Thermodynamics

Physiology

Concepts & Ideas

Genes & Molecular Sequences

Amino Acid Sequences

Chemicals & Drugs

Phenomena

Co-author Network

Publications

TOP 3
Gerald R Grimsley; Richard L Thurlkill; Saul R Trevino; J Martin Scholtz
Determining the conformational stability of a protein from urea and thermal unfolding curves.
Ryan M Kramer; Nicole Motl; C Nick Pace; Varad R Shende; J Martin Scholtz
Toward a molecular understanding of protein solubility: increased negative surface charge correlates with increased solubility.
C Nick Pace; Hailong Fu; Katrina Lee Fryar; John Landua; Saul R Trevino; Bret A Shirley; Marsha McNutt Hendricks; Satoshi Iimura; Ketan Gajiwala; J Martin Scholtz; Gerald R Grimsley
Contribution of hydrophobic interactions to protein stability.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Martin Scholtz (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Gerald R Grimsley; Richard L Thurlkill; Saul R Trevino; J Martin Scholtz
Determining the conformational stability of a protein from urea and thermal unfolding curves.
Current protocols in protein science / editorial board, John E. Coligan ... [et al.] 2013;Chapter 28():Unit28.4.
2012: Ryan M Kramer; Nicole Motl; C Nick Pace; Varad R Shende; J Martin Scholtz
Toward a molecular understanding of protein solubility: increased negative surface charge correlates with increased solubility.
Biophysical journal 2012;102(8):1907-15.
2011: C Nick Pace; Hailong Fu; Katrina Lee Fryar; John Landua; Saul R Trevino; Bret A Shirley; Marsha McNutt Hendricks; Satoshi Iimura; Ketan Gajiwala; J Martin Scholtz; Gerald R Grimsley
Contribution of hydrophobic interactions to protein stability.
Journal of molecular biology 2011;408(3):514-28.
2010: Hailong Fu; Gerald R Grimsley; J Martin Scholtz; C Nick Pace
Increasing protein stability: importance of DeltaC(p) and the denatured state.
Protein science : a publication of the Protein Society 2010;19(5):1044-52.
2010: C Nick Pace; Beatrice M P Huyghues-Despointes; Hailong Fu; Kazufumi Takano; J Martin Scholtz; Gerald R Grimsley
Urea denatured state ensembles contain extensive secondary structure that is increased in hydrophobic proteins.
Protein science : a publication of the Protein Society 2010;19(5):929-43.
2010: Janel R McLean; John A McLean; Zhaoxiang Wu; Christopher Becker; Lisa M Pérez; C Nick Pace; J Martin Scholtz; David H Russell
Factors that influence helical preferences for singly charged gas-phase peptide ions: the effects of multiple potential charge-carrying sites.
The journal of physical chemistry. B 2010;114(2):809-16.
2009: Hailong Fu; Gerald R Grimsley; Abbas Razvi; J Martin Scholtz; C Nick Pace
Increasing protein stability by improving beta-turns.
Proteins 2009;77(3):491-8.
2009: Younhee Cho; Laura B Sagle; Satoshi Iimura; Yanjie Zhang; Jaibir Kherb; Ashutosh Chilkoti; J Martin Scholtz; Paul S Cremer
Hydrogen bonding of beta-turn structure is stabilized in D(2)O.
Journal of the American Chemical Society 2009;131(42):15188-93.
2009: C Nick Pace; Gerald R Grimsley; J Martin Scholtz
Protein ionizable groups: pK values and their contribution to protein stability and solubility.
The Journal of biological chemistry 2009;284(20):13285-9.
2009: J Martin Scholtz; Gerald R Grimsley; C Nick Pace
Solvent denaturation of proteins and interpretations of the m value.
Methods in enzymology 2009;466():549-65.
2009: Gerald R Grimsley; J Martin Scholtz; C Nick Pace
A summary of the measured pK values of the ionizable groups in folded proteins.
Protein science : a publication of the Protein Society 2009;18(1):247-51.
2008: Saul R Trevino; J Martin Scholtz; C Nick Pace
Measuring and increasing protein solubility.
Journal of pharmaceutical sciences 2008;97(10):4155-66.
2008: Roy W Alston; Mauricio Lasagna; Gerald R Grimsley; J Martin Scholtz; Gregory D Reinhart; C Nick Pace
Peptide sequence and conformation strongly influence tryptophan fluorescence.
Biophysical journal 2008;94(6):2280-7.
2008: Roy W Alston; Mauricio Lasagna; Gerald R Grimsley; J Martin Scholtz; Gregory D Reinhart; C Nick Pace
Tryptophan fluorescence reveals the presence of long-range interactions in the denatured state of ribonuclease Sa.
Biophysical journal 2008;94(6):2288-96.
2007: Yun Wei; Beatrice M P Huyghues-Despointes; Jerry Tsai; J Martin Scholtz
NMR study and molecular dynamics simulations of optimized beta-hairpin fragments of protein G.
Proteins 2007;69(2):285-96.
2007: Saul R Trevino; Stephanie Schaefer; J Martin Scholtz; C Nick Pace
Increasing protein conformational stability by optimizing beta-turn sequence.
Journal of molecular biology 2007;373(1):211-8.
2007: Carl P Goodrich; Serdal Kirmizialtin; Beatrice M Huyghues-Despointes; Aiping Zhu; J Martin Scholtz; Dmitrii E Makarov; Liviu Movileanu
Single-molecule electrophoresis of beta-hairpin peptides by electrical recordings and Langevin dynamics simulations.
The journal of physical chemistry. B 2007;111(13):3332-5.
2007: Saul R Trevino; J Martin Scholtz; C Nick Pace
Amino acid contribution to protein solubility: Asp, Glu, and Ser contribute more favorably than the other hydrophilic amino acids in RNase Sa.
Journal of molecular biology 2007;366(2):449-60.
2006: Richard L Thurlkill; Gerald R Grimsley; J Martin Scholtz; C Nick Pace
Hydrogen bonding markedly reduces the pK of buried carboxyl groups in proteins.
Journal of molecular biology 2006;362(3):594-604.
2006: Abbas Razvi; J Martin Scholtz
Lessons in stability from thermophilic proteins.
Protein science : a publication of the Protein Society 2006;15(7):1569-78.
2006: Beatrice M P Huyghues-Despointes; Xiaotoa Qu; Jerry Tsai; J Martin Scholtz
Terminal ion pairs stabilize the second beta-hairpin of the B1 domain of protein G.
Proteins 2006;63(4):1005-17.
2006: Richard L Thurlkill; Gerald R Grimsley; J Martin Scholtz; C Nick Pace
pK values of the ionizable groups of proteins.
Protein science : a publication of the Protein Society 2006;15(5):1214-8.
2006: David Schell; Jerry Tsai; J Martin Scholtz; C Nick Pace
Hydrogen bonding increases packing density in the protein interior.
Proteins 2006;63(2):278-82.
2006: Abbas Razvi; J Martin Scholtz
A thermodynamic comparison of HPr proteins from extremophilic organisms.
Biochemistry 2006;45(13):4084-92.
2006: Gerald R Grimsley; Beatrice M P Huyghues-Despointes; C Nick Pace; J Martin Scholtz
Measuring the conformational stability of a protein by NMR.
CSH protocols 2006;2006(1):.
2006: Gerald R Grimsley; Beatrice M P Huyghues-Despointes; C Nick Pace; J Martin Scholtz
Determining a thermal unfolding curve.
CSH protocols 2006;2006(1):.
2006: Gerald R Grimsley; Beatrice M P Huyghues-Despointes; C Nick Pace; J Martin Scholtz
Determining a urea or guanidinium chloride unfolding curve.
CSH protocols 2006;2006(1):.
2006: Gerald R Grimsley; Beatrice M P Huyghues-Despointes; C Nick Pace; J Martin Scholtz
Preparation of urea and guanidinium chloride stock solutions for measuring denaturant-induced unfolding curves.
CSH protocols 2006;2006(1):.
2005: Saul R Trevino; Kuppan Gokulan; Stephanie Newsom; Richard L Thurlkill; Kevin L Shaw; Vladmir Mitkevich; Alexander A Makarov; James C Sacchettini; J Martin Scholtz; C Nick Pace
Asp79 makes a large, unfavorable contribution to the stability of RNase Sa.
Journal of molecular biology 2005;354(4):967-78.
2005: Richard L Thurlkill; David A Cross; J Martin Scholtz; C Nick Pace
pKa of fentanyl varies with temperature: implications for acid-base management during extremes of body temperature.
Journal of cardiothoracic and vascular anesthesia 2005;19(6):759-62.
2005: Liviu Movileanu; Jason P Schmittschmitt; J Martin Scholtz; Hagan Bayley
Interactions of peptides with a protein pore.
Biophysical journal 2005;89(2):1030-45.
2005: Jared M Trefethen; C Nick Pace; J Martin Scholtz; David N Brems
Charge-charge interactions in the denatured state influence the folding kinetics of ribonuclease Sa.
Protein science : a publication of the Protein Society 2005;14(7):1934-8.
2005: Douglas V Laurents; J Martin Scholtz; Manuel Rico; C Nick Pace; Marta Bruix
Ribonuclease Sa conformational stability studied by NMR-monitored hydrogen exchange.
Biochemistry 2005;44(21):7644-55.
2005: sudharsan sridharan; Abbas Razvi; J Martin Scholtz; James C Sacchettini
The HPr proteins from the thermophile Bacillus stearothermophilus can form domain-swapped dimers.
Journal of molecular biology 2005;346(3):919-31.
2004: Roy W Alston; Lubica Urbanikova; Jozef Sevcik; Mauricio Lasagna; Gregory D Reinhart; J Martin Scholtz; C Nick Pace
Contribution of single tryptophan residues to the fluorescence and stability of ribonuclease Sa.
Biophysical journal 2004;87(6):4036-47.
2004: C Nick Pace; Saul Treviño; Erode Prabhakaran; J Martin Scholtz
Protein structure, stability and solubility in water and other solvents.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2004;359(1448):1225-34; discussion 1234-5.
2004: Jason P Schmittschmitt; J Martin Scholtz
The side chain of aspartic acid 69 dictates the folding mechanism of Bacillus subtilis HPr.
Biochemistry 2004;43(5):1360-8.
2003: Jason P Schmittschmitt; J Martin Scholtz
The role of protein stability, solubility, and net charge in amyloid fibril formation.
Protein science : a publication of the Protein Society 2003;12(10):2374-8.
2003: Kazufumi Takano; J Martin Scholtz; James C Sacchettini; C Nick Pace
The contribution of polar group burial to protein stability is strongly context-dependent.
The Journal of biological chemistry 2003;278(34):31790-5.
2003: Beatrice M P Huyghues-Despointes; Richard L Thurlkill; Michael D Daily; David Schell; James M Briggs; Jan M Antosiewicz; C Nick Pace; J Martin Scholtz
pK values of histidine residues in ribonuclease Sa: effect of salt and net charge.
Journal of molecular biology 2003;325(5):1093-105.
2003: Douglas V Laurents; Beatrice M P Huyghues-Despointes; Marta Bruix; Richard L Thurlkill; David Schell; Stephanie Newsom; Gerald R Grimsley; Kevin L Shaw; Saul Treviño; Manuel Rico; James M Briggs; Jan M Antosiewicz; J Martin Scholtz; C Nick Pace
Charge-charge interactions are key determinants of the pK values of ionizable groups in ribonuclease Sa (pI=3.5) and a basic variant (pI=10.2).
Journal of molecular biology 2003;325(5):1077-92.
2003: Guang Song; Shawna Thomas; Ken A Dill; J Martin Scholtz; Nancy M Amato
A path planning-based study of protein folding with a case study of hairpin formation in protein G and L.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing 2003;():240-51.
2002: C Nick Pace; Beatrice M P Huyghues-Despointes; James M Briggs; Gerald R Grimsley; J Martin Scholtz
Charge-charge interactions are the primary determinants of the pK values of the ionizable groups in Ribonuclease T1.
Biophysical chemistry 2002;101-102():211-9.
2002: Eric M Nicholson; Ronald W Peterson; J Martin Scholtz
A partially buried site in homologous HPr proteins is not optimized for stability.
Journal of molecular biology 2002;321(2):355-62.
2002: Scott A Celinski; J Martin Scholtz
Osmolyte effects on helix formation in peptides and the stability of coiled-coils.
Protein science : a publication of the Protein Society 2002;11(8):2048-51.
2001: C Nick Pace; G Horn; EJ Hebert; Charles Bechert; K Shaw; Lubica Urbanikova; J Martin Scholtz; Jozef Sevcik
Tyrosine hydrogen bonds make a large contribution to protein stability.
Journal of molecular biology 2001;312(2):393-404.
2001: Beatrice M P Huyghues-Despointes; C Nick Pace; S W Englander; J Martin Scholtz
Measuring the conformational stability of a protein by hydrogen exchange.
Methods in molecular biology (Clifton, N.J.) 2001;168():69-92.
2001: H Zhu; Scott A Celinski; J Martin Scholtz; James C Hu
An engineered leucine zipper a position mutant with an unusual three-state unfolding pathway.
Protein science : a publication of the Protein Society 2001;10(1):24-33.
2000: H Zhu; Scott A Celinski; J Martin Scholtz; James C Hu
The contribution of buried polar groups to the conformational stability of the GCN4 coiled coil.
Journal of molecular biology 2000;300(5):1377-87.
1999: Beatrice M P Huyghues-Despointes; U Langhorst; Jan Steyaert; C Nick Pace; J Martin Scholtz
Hydrogen-exchange stabilities of RNase T1 and variants with buried and solvent-exposed Ala --> Gly mutations in the helix.
Biochemistry 1999;38(50):16481-90.
1999: Beatrice M P Huyghues-Despointes; J Martin Scholtz; C Nick Pace
Protein conformational stabilities can be determined from hydrogen exchange rates.
Nature structural biology 1999;6(10):910-2.
1999: Gerald R Grimsley; Kevin L Shaw; L R Fee; Roy W Alston; Beatrice M P Huyghues-Despointes; Richard L Thurlkill; J Martin Scholtz; C Nick Pace
Increasing protein stability by altering long-range coulombic interactions.
Protein science : a publication of the Protein Society 1999;8(9):1843-9.
1999: P Krishnan; Anne M Hocking; J Martin Scholtz; C N Pace; K K Holik; David J McQuillan
Distinct secondary structures of the leucine-rich repeat proteoglycans decorin and biglycan. Glycosylation-dependent conformational stability.
The Journal of biological chemistry 1999;274(16):10945-50.
1999: R W Peterson; E M Nicholson; Roopa Thapar; R E Klevit; J Martin Scholtz
Increased helix and protein stability through the introduction of a new tertiary hydrogen bond.
Journal of molecular biology 1999;286(5):1609-19.
1998: C Nick Pace; J Martin Scholtz
A helix propensity scale based on experimental studies of peptides and proteins.
Biophysical journal 1998;75(1):422-7.
1998: DL Smith; Douglas K Struck; J Martin Scholtz; Ry Young
Purification and biochemical characterization of the lambda holin.
Journal of bacteriology 1998;180(9):2531-40.
1998: JK Myers; C Nick Pace; J Martin Scholtz
Trifluoroethanol effects on helix propensity and electrostatic interactions in the helical peptide from ribonuclease T1.
Protein science : a publication of the Protein Society 1998;7(2):383-8.
1998: J S Smith; J Martin Scholtz
Energetics of polar side-chain interactions in helical peptides: salt effects on ion pairs and hydrogen bonds.
Biochemistry 1998;37(1):33-40.
1997: Janet K Grimsley; J Martin Scholtz; C Nick Pace; James R Wild
Organophosphorus hydrolase is a remarkably stable enzyme that unfolds through a homodimeric intermediate.
Biochemistry 1997;36(47):14366-74.
1997: JK Myers; C Nick Pace; J Martin Scholtz
Helix propensities are identical in proteins and peptides.
Biochemistry 1997;36(36):10923-9.
1997: JK Myers; C Nick Pace; J Martin Scholtz
A direct comparison of helix propensity in proteins and peptides.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(7):2833-7.
1996: M E Huffine; J Martin Scholtz
Energetic implications for protein phosphorylation. Conformational stability of HPr variants that mimic phosphorylated forms.
The Journal of biological chemistry 1996;271(46):28898-902.
1996: J K Myers; J S Smith; C Nick Pace; J Martin Scholtz
The alpha-helix of ribonuclease T1 as an independent stability unit: direct comparison of peptide and protein stability.
Journal of molecular biology 1996;263(3):390-5.
1996: E M Nicholson; J Martin Scholtz
Conformational stability of the Escherichia coli HPr protein: test of the linear extrapolation method and a thermodynamic characterization of cold denaturation.
Biochemistry 1996;35(35):11369-78.
1996: Roopa Thapar; E M Nicholson; Ponni Rajagopal; E Bruce Waygood; J Martin Scholtz; Rachel E Klevit
Influence of N-cap mutations on the structure and stability of Escherichia coli HPr.
Biochemistry 1996;35(35):11268-77.
1996: J S Smith; J Martin Scholtz
Guanidine hydrochloride unfolding of peptide helices: separation of denaturant and salt effects.
Biochemistry 1996;35(22):7292-7.
1995: K Pullen; Ponni Rajagopal; B R Branchini; M E Huffine; J Reizer; M H Saier; J Martin Scholtz; Rachel E Klevit
Phosphorylation of serine-46 in HPr, a key regulatory protein in bacteria, results in stabilization of its solution structure.
Protein science : a publication of the Protein Society 1995;4(12):2478-86.
1995: J K Myers; C Nick Pace; J Martin Scholtz
Denaturant m values and heat capacity changes: relation to changes in accessible surface areas of protein unfolding.
Protein science : a publication of the Protein Society 1995;4(10):2138-48.
1995: P K Hammen; J Martin Scholtz; J W Anderson; E Bruce Waygood; Rachel E Klevit
Investigation of a side-chain-side-chain hydrogen bond by mutagenesis, thermodynamics, and NMR spectroscopy.
Protein science : a publication of the Protein Society 1995;4(5):936-44.
1995: J Martin Scholtz; D Barrick; E J York; J M Stewart; Robert L Baldwin
Urea unfolding of peptide helices as a model for interpreting protein unfolding.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(1):185-9.
1995: J Martin Scholtz
Conformational stability of HPr: the histidine-containing phosphocarrier protein from Bacillus subtilis.
Protein science : a publication of the Protein Society 1995;4(1):35-43.
1995: J Martin Scholtz; A D Robertson
Hydrogen exchange techniques.
Methods in molecular biology (Clifton, N.J.) 1995;40():291-311.
1993: Beatrice M P Huyghues-Despointes; J Martin Scholtz; Robert L Baldwin
Effect of a single aspartate on helix stability at different positions in a neutral alanine-based peptide.
Protein science : a publication of the Protein Society 1993;2(10):1604-11.
1993: J Martin Scholtz; H Qian; V H Robbins; Robert L Baldwin
The energetics of ion-pair and hydrogen-bonding interactions in a helical peptide.
Biochemistry 1993;32(37):9668-76.
1993: J Martin Scholtz; Robert L Baldwin
Perchlorate-induced denaturation of ribonuclease A: investigation of possible folding intermediates.
Biochemistry 1993;32(17):4604-8.
1993: Beatrice M P Huyghues-Despointes; J Martin Scholtz; Robert L Baldwin
Helical peptides with three pairs of Asp-Arg and Glu-Arg residues in different orientations and spacings.
Protein science : a publication of the Protein Society 1993;2(1):80-5.
1992: C A Rohl; J Martin Scholtz; E J York; J M Stewart; Robert L Baldwin
Kinetics of amide proton exchange in helical peptides of varying chain lengths. Interpretation by the Lifson-Roig equation.
Biochemistry 1992;31(5):1263-9.
1992: J Martin Scholtz; Robert L Baldwin
The mechanism of alpha-helix formation by peptides.
Annual review of biophysics and biomolecular structure 1992;21():95-118.
1991: J Martin Scholtz; H Qian; E J York; J M Stewart; Robert L Baldwin
Parameters of helix-coil transition theory for alanine-based peptides of varying chain lengths in water.
Biopolymers 1991;31(13):1463-70.
1991: J Martin Scholtz; Susan Marqusee; Robert L Baldwin; E J York; J M Stewart; M Santoro; David Bolen
Calorimetric determination of the enthalpy change for the alpha-helix to coil transition of an alanine peptide in water.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(7):2854-8.