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Magnus Schou

Research Profile

Chemicals & Drugs

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Radiometry

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Anton Forsberg; Yvonne Freund-Levi; Christer Halldin; Fredrik Jeppsson; Peter Johnström; Per Julin; Anders Juréus; Johan Sandell; Magnus Schou; Jan Andersson; Zsolt Cselényi; Maria Eriksdotter; Lars Farde; Britt-Marie Swahn; Katarina Varnäs; Samuel Svensson
Low background and high contrast PET imaging of amyloid-β with [11C]AZD2995 and [11C]AZD2184 in Alzheimer's disease patients.
Nahid Amini; Ryuji Nakao; Magnus Schou; Christer Halldin
Identification of PET radiometabolites by cytochrome P450, UHPLC/Q-ToF-MS and fast radio-LC: applied to the PET radioligands [11C]flumazenil, [18F]FE-PE2I, and [11C]PBR28.
Ryuji Nakao; Magnus Schou; Christer Halldin
Rapid metabolite analysis of positron emission tomography radioligands by direct plasma injection combining micellar cleanup with high submicellar liquid chromatography with radiometric detection.

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All Publications

2013: Anton Forsberg; Yvonne Freund-Levi; Christer Halldin; Fredrik Jeppsson; Peter Johnström; Per Julin; Anders Juréus; Johan Sandell; Magnus Schou; Jan Andersson; Zsolt Cselényi; Maria Eriksdotter; Lars Farde; Britt-Marie Swahn; Katarina Varnäs; Samuel Svensson
Low background and high contrast PET imaging of amyloid-β with [11C]AZD2995 and [11C]AZD2184 in Alzheimer's disease patients.
European journal of nuclear medicine and molecular imaging 2013;40(4):580-93.
2013: Nahid Amini; Ryuji Nakao; Magnus Schou; Christer Halldin
Identification of PET radiometabolites by cytochrome P450, UHPLC/Q-ToF-MS and fast radio-LC: applied to the PET radioligands [11C]flumazenil, [18F]FE-PE2I, and [11C]PBR28.
Analytical and bioanalytical chemistry 2013;405(4):1303-10.
2012: Ryuji Nakao; Magnus Schou; Christer Halldin
Rapid metabolite analysis of positron emission tomography radioligands by direct plasma injection combining micellar cleanup with high submicellar liquid chromatography with radiometric detection.
Journal of chromatography. A 2012;1266():76-83.
2012: Ryuji Nakao; Magnus Schou; Christer Halldin
Rapid and sensitive measurement of PET radioligands in plasma by fast liquid chromatography/radiometric detection.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2012;895-896():116-22.
2012: Ryuji Nakao; Magnus Schou; Christer Halldin
Direct plasma metabolite analysis of positron emission tomography radioligands by micellar liquid chromatography with radiometric detection.
Analytical chemistry 2012;84(7):3222-30.
2009: Andrea Varrone; Carsten Steiger; Magnus Schou; Akihiro Takano; Sjoerd J Finnema; Denis Guilloteau; Balázs Gulyás; Christer Halldin
In vitro autoradiography and in vivo evaluation in cynomolgus monkey of [18F]FE-PE2I, a new dopamine transporter PET radioligand.
Synapse (New York, N.Y.) 2009;63(10):871-80.
2009: Magnus Schou; Carsten Steiger; Andrea Varrone; Denis Guilloteau; Christer Halldin
Synthesis, radiolabeling and preliminary in vivo evaluation of [18F]FE-PE2I, a new probe for the dopamine transporter.
Bioorganic & medicinal chemistry letters 2009;19(16):4843-5.
2009: Magnus Schou; Sami S Zoghbi; H Umesha Shetty; Evgeny Shchukin; Jeih-San Liow; Jinsoo Hong; Bengt A Andrée; Balázs Gulyás; Lars Farde; Robert B Innis; Victor W Pike; Christer Halldin
Investigation of the metabolites of (S,S)-[(11)C]MeNER in humans, monkeys and rats.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2009;11(1):23-30.
2008: Akihiro Takano; Christer Halldin; Andrea Varrone; Per Karlsson; Nils Sjöholm; James B Stubbs; Magnus Schou; Anu J Airaksinen; Johannes Tauscher; Balázs Gulyás
Biodistribution and radiation dosimetry of the norepinephrine transporter radioligand (S,S)-[18F]FMeNER-D2: a human whole-body PET study.
European journal of nuclear medicine and molecular imaging 2008;35(3):630-6.
2008: Akihiro Takano; Balázs Gulyás; Andrea Varrone; Per Karlsson; Magnus Schou; Anu J Airaksinen; Francois Vandenhende; Johannes Tauscher; Christer Halldin
Imaging the norepinephrine transporter with positron emission tomography: initial human studies with (S,S)-[18F]FMeNER-D2.
European journal of nuclear medicine and molecular imaging 2008;35(1):153-7.
2007: Magnus Schou; Victor W Pike; Judit Sóvágó; Balázs Gulyás; Peter T Gallagher; David Dobson; Magnus W Walter; Helene Rudyk; Lars Farde; Christer Halldin
Synthesis of 11C-labelled (R)-OHDMI and CFMME and their evaluation as candidate radioligands for imaging central norepinephrine transporters with PET.
Bioorganic & medicinal chemistry 2007;15(2):616-25.
2007: Magnus Schou; Victor W Pike; Christer Halldin
Development of radioligands for imaging of brain norepinephrine transporters in vivo with positron emission tomography.
Current topics in medicinal chemistry 2007;7(18):1806-16.
2006: Nicholas Seneca; Balázs Gulyás; Andrea Varrone; Magnus Schou; Anu Airaksinen; Johannes Tauscher; Francois Vandenhende; William Kielbasa; Lars Farde; Robert B Innis; Christer Halldin
Atomoxetine occupies the norepinephrine transporter in a dose-dependent fashion: a PET study in nonhuman primate brain using (S,S)-[18F]FMeNER-D2.
Psychopharmacology 2006;188(1):119-27.
2006: Magnus Schou; Judit Sóvágó; Victor W Pike; Balázs Gulyás; Klaus P Bøgesø; Lars Farde; Christer Halldin
Synthesis and positron emission tomography evaluation of three norepinephrine transporter radioligands: [C-11]desipramine, [C-11]talopram and [C-11]talsupram.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2006;8(1):1-8.
2005: Judit Sóvágó; Lars Farde; Christer Halldin; Evgenij Schukin; Magnus Schou; István Laszlovszky; Béla Kiss; Balázs Gulyás
Lack of effect of reserpine-induced dopamine depletion on the binding of the dopamine-D3 selective radioligand, [11C]RGH-1756.
Brain research bulletin 2005;67(3):219-24.
2005: Magnus Schou; Christer Halldin; Victor W Pike; P David Mozley; David Dobson; Robert B Innis; Lars Farde; Håkan Hall
Post-mortem human brain autoradiography of the norepinephrine transporter using (S,S)-[18F]FMeNER-D2.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2005;15(5):517-20.
2005: Nicholas Seneca; Bengt Andree; Nils Sjoholm; Magnus Schou; Stefan Pauli; P David Mozley; James B Stubbs; Jeih-San Liow; Judit Sovago; Balázs Gulyás; Robert B Innis; Christer Halldin
Whole-body biodistribution, radiation dosimetry estimates for the PET norepinephrine transporter probe (S,S)-[18F]FMeNER-D2 in non-human primates.
Nuclear medicine communications 2005;26(8):695-700.
2005: Subroto Ghose; Masahiro Fujita; Paul Morrison; George R. Uhl; Dennis L Murphy; P David Mozley; Magnus Schou; Christer Halldin; Robert B Innis
Specific in vitro binding of (S,S)-[3H]MeNER to norepinephrine transporters.
Synapse (New York, N.Y.) 2005;56(2):100-4.
2004: Magnus Schou; Christer Halldin; Judit Sóvágó; Victor W Pike; Håkan Hall; Balázs Gulyás; P David Mozley; David Dobson; Evgeny Shchukin; Robert B Innis; Lars Farde
PET evaluation of novel radiofluorinated reboxetine analogs as norepinephrine transporter probes in the monkey brain.
Synapse (New York, N.Y.) 2004;53(2):57-67.
2003: Magnus Schou; Christer Halldin; Judit Sóvágó; Victor W Pike; Balázs Gulyás; P David Mozley; David P Johnson; Håkan Hall; Robert B Innis; Lars Farde
Specific in vivo binding to the norepinephrine transporter demonstrated with the PET radioligand, (S,S)-[11C]MeNER.
Nuclear medicine and biology 2003;30(7):707-14.