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Nicholas Schramek

Research Profile

Chemicals & Drugs

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Escherichia coli

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Amino Acid Sequences

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Publications

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Nicholas Schramek; Huahong Wang; Werner Römisch-Margl; Birgit Keil; Tanja Radykewicz; Bernhard Winzenhörlein; Ludger Beerhues; Adelbert Bacher; Felix Rohdich; Jonathan Gershenzon; Benye Liu; Wolfgang Eisenreich
Artemisinin biosynthesis in growing plants of Artemisia annua. A 13CO2 study.
Elena Ostrozhenkova; Eva Eylert; Nicholas Schramek; Avi Golan-Goldhirsh; Adelbert Bacher; Wolfgang Eisenreich
Biosynthesis of the chromogen hermidin from Mercurialis annua L.
Werner Römisch-Margl; Nicholas Schramek; Tanja Radykewicz; Christian Ettenhuber; Eva Eylert; Claudia Huber; Lilla Römisch-Margl; Christine Schwarz; Maria Dobner; Norbert Demmel; Bernhard Winzenhörlein; Adelbert Bacher; Wolfgang Eisenreich
13CO2 as a universal metabolic tracer in isotopologue perturbation experiments.

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All Publications

2010: Nicholas Schramek; Huahong Wang; Werner Römisch-Margl; Birgit Keil; Tanja Radykewicz; Bernhard Winzenhörlein; Ludger Beerhues; Adelbert Bacher; Felix Rohdich; Jonathan Gershenzon; Benye Liu; Wolfgang Eisenreich
Artemisinin biosynthesis in growing plants of Artemisia annua. A 13CO2 study.
Phytochemistry 2010;71(2-3):179-87.
2007: Elena Ostrozhenkova; Eva Eylert; Nicholas Schramek; Avi Golan-Goldhirsh; Adelbert Bacher; Wolfgang Eisenreich
Biosynthesis of the chromogen hermidin from Mercurialis annua L.
Phytochemistry 2007;68(22-24):2816-24.
2007: Werner Römisch-Margl; Nicholas Schramek; Tanja Radykewicz; Christian Ettenhuber; Eva Eylert; Claudia Huber; Lilla Römisch-Margl; Christine Schwarz; Maria Dobner; Norbert Demmel; Bernhard Winzenhörlein; Adelbert Bacher; Wolfgang Eisenreich
13CO2 as a universal metabolic tracer in isotopologue perturbation experiments.
Phytochemistry 2007;68(16-18):2273-89.
2005: Ferdinand Zepeck; Tobias Gräwert; Johannes Kaiser; Nicholas Schramek; Wolfgang Eisenreich; Adelbert Bacher; Felix Rohdich
Biosynthesis of isoprenoids. purification and properties of IspG protein from Escherichia coli.
The Journal of organic chemistry 2005;70(23):9168-74.
2005: Boris Illarionov; Wolfgang Eisenreich; Nicholas Schramek; Adelbert Bacher; Markus Fischer
Biosynthesis of vitamin B2: diastereomeric reaction intermediates of archaeal and non-archaeal riboflavin synthases.
The Journal of biological chemistry 2005;280(31):28541-6.
2005: Markus Fischer; Ilka Haase; Richard Feicht; Nicholas Schramek; Peter Köhler; Peter Schieberle; Adelbert Bacher
Evolution of vitamin B2 biosynthesis: riboflavin synthase of Arabidopsis thaliana and its inhibition by riboflavin.
Biological chemistry 2005;386(5):417-28.
2005: Boris Illarionov; Ilka Haase; Markus Fischer; Adelbert Bacher; Nicholas Schramek
Pre-steady-state kinetic analysis of riboflavin synthase using a pentacyclic reaction intermediate as substrate.
Biological chemistry 2005;386(2):127-36.
2004: Tobias Gräwert; Johannes Kaiser; Ferdinand Zepeck; Ralf Laupitz; Stefan Hecht; Sabine Amslinger; Nicholas Schramek; Erik Schleicher; Stefan Weber; Martin Haslbeck; Johannes Buchner; Christoph Rieder; Duilio Arigoni; Adelbert Bacher; Wolfgang Eisenreich; Felix Rohdich
IspH protein of Escherichia coli: studies on iron-sulfur cluster implementation and catalysis.
Journal of the American Chemical Society 2004;126(40):12847-55.
2004: Ralf Laupitz; Stefan Hecht; Sabine Amslinger; Ferdinand Zepeck; Johannes Kaiser; Gerald Richter; Nicholas Schramek; Stefan Steinbacher; Robert Huber; Duilio Arigoni; Adelbert Bacher; Wolfgang Eisenreich; Felix Rohdich
Biochemical characterization of Bacillus subtilis type II isopentenyl diphosphate isomerase, and phylogenetic distribution of isoprenoid biosynthesis pathways.
European journal of biochemistry / FEBS 2004;271(13):2658-69.
2003: Boris Illarionov; Ilka Haase; Adelbert Bacher; Markus Fischer; Nicholas Schramek
Presteady state kinetic analysis of riboflavin synthase.
The Journal of biological chemistry 2003;278(48):47700-6.
2003: Ilka Haase; Markus Fischer; Adelbert Bacher; Nicholas Schramek
Temperature-dependent presteady state kinetics of lumazine synthase from the hyperthermophilic eubacterium Aquifex aeolicus.
The Journal of biological chemistry 2003;278(39):37909-15.
2003: Nicholas Schramek; Ilka Haase; Markus Fischer; Adelbert Bacher
Biosynthesis of riboflavin. Single turnover kinetic analysis of 6,7-dimethyl-8-ribityllumazine synthase.
Journal of the American Chemical Society 2003;125(15):4460-6.
2003: Markus Fischer; Ilka Haase; Klaus Kis; Winfried Meining; Rudolf Ladenstein; Mark Cushman; Nicholas Schramek; Robert Huber; Adelbert Bacher
Enzyme catalysis via control of activation entropy: site-directed mutagenesis of 6,7-dimethyl-8-ribityllumazine synthase.
Journal of molecular biology 2003;326(3):783-93.
2003: Jorge Rebelo; Guenter Auerbach; Gerd Bader; Andreas Bracher; Herbert Nar; Cornelia Hösl; Nicholas Schramek; Johannes Kaiser; Adelbert Bacher; Robert Huber; Markus Fischer
Biosynthesis of pteridines. Reaction mechanism of GTP cyclohydrolase I.
Journal of molecular biology 2003;326(2):503-16.
2002: Johannes Kaiser; Nicholas Schramek; Sabine Eberhardt; Stefanie Püttmer; Michael Schuster; Adelbert Bacher
Biosynthesis of vitamin B2.
European journal of biochemistry / FEBS 2002;269(21):5264-70.
2002: Nicholas Schramek; Andreas Bracher; Markus Fischer; Guenter Auerbach; Herbert Nar; Robert Huber; Adelbert Bacher
Reaction mechanism of GTP cyclohydrolase I: single turnover experiments using a kinetically competent reaction intermediate.
Journal of molecular biology 2002;316(3):829-37.
2002: Vered Holdengreber; Cornelia Krieger; Markus Gütlich; Nicholas Schramek; Michal Vechoropoulos; Markus Fischer; Adelbert Bacher; Yehuda Ben-Shaul
Localization of two enzymes of the tetrahydrobiopterin biosynthetic pathway in embryonic chick retina.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2002;50(2):265-74.
2001: Nicholas Schramek; Andreas Bracher; Adelbert Bacher
Biosynthesis of riboflavin. Single turnover kinetic analysis of GTP cyclohydrolase II.
The Journal of biological chemistry 2001;276(47):44157-62.
2001: Andreas Bracher; Nicholas Schramek; Adelbert Bacher
Biosynthesis of pteridines. Stopped-flow kinetic analysis of GTP cyclohydrolase I.
Biochemistry 2001;40(26):7896-902.
2001: H Ritz; Nicholas Schramek; Andreas Bracher; Stefan Herz; Wolfgang Eisenreich; Gerald Richter; Adelbert Bacher
Biosynthesis of riboflavin: studies on the mechanism of GTP cyclohydrolase II.
The Journal of biological chemistry 2001;276(25):22273-7.
2001: Nicholas Schramek; Andreas Bracher; Adelbert Bacher
Ring opening is not rate-limiting in the GTP cyclohydrolase I reaction.
The Journal of biological chemistry 2001;276(4):2622-6.
2000: Felix Rohdich; Juraithip Wungsintaweekul; H Luttgen; Markus Fischer; Wolfgang Eisenreich; Christoph A Schuhr; Monika Fellermeier; Nicholas Schramek; Meinhart H Zenk; Adelbert Bacher
Biosynthesis of terpenoids: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase from tomato.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(15):8251-6.
1999: Andreas Bracher; Markus Fischer; Wolfgang Eisenreich; H Ritz; Nicholas Schramek; P Boyle; P Gentili; Robert Huber; Herbert Nar; Guenter Auerbach; Adelbert Bacher
Histidine 179 mutants of GTP cyclohydrolase I catalyze the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone triphosphate.
The Journal of biological chemistry 1999;274(24):16727-35.
1999: R Mancini; Francesca Saracino; Giacomo Buscemi; M Fischer; Nicholas Schramek; Andreas Bracher; Adelbert Bacher; Markus Gütlich; Maria Louisa Agostoni Carbone
Complementation of the fol2 deletion in Saccharomyces cerevisiae by human and Escherichia coli genes encoding GTP cyclohydrolase I.
Biochemical and biophysical research communications 1999;255(2):521-7.
1998: Andreas Bracher; Wolfgang Eisenreich; Nicholas Schramek; H Ritz; E Götze; A Herrmann; Markus Gütlich; Adelbert Bacher
Biosynthesis of pteridines. NMR studies on the reaction mechanisms of GTP cyclohydrolase I, pyruvoyltetrahydropterin synthase, and sepiapterin reductase.
The Journal of biological chemistry 1998;273(43):28132-41.