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Randy Blakely

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TOP 3
Nicole L Baganz; Randy D Blakely
A dialogue between the immune system and brain, spoken in the language of serotonin.
Amy E Moritz; Harald H Sitte; Jae-Won Yang; Randy D Blakely; James D Foster; Balachandra Gorentla; Michelle S Mazei-Robison; Roxanne A Vaughan
Phosphorylation of dopamine transporter serine 7 modulates cocaine analog binding.
Lilia Zurkovsky; Randy D Blakely; Evgeny Bychkov; Carley Siedlecki; Elviche L Tsakem; Eugenia V Gurevich
Cognitive effects of dopamine depletion in the context of diminished acetylcholine signaling capacity in mice.

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All Publications

2013: Nicole L Baganz; Randy D Blakely
A dialogue between the immune system and brain, spoken in the language of serotonin.
ACS chemical neuroscience 2013;4(1):48-63.
2013: Amy E Moritz; Harald H Sitte; Jae-Won Yang; Randy D Blakely; James D Foster; Balachandra Gorentla; Michelle S Mazei-Robison; Roxanne A Vaughan
Phosphorylation of dopamine transporter serine 7 modulates cocaine analog binding.
The Journal of biological chemistry 2013;288(1):20-32.
2013: Lilia Zurkovsky; Randy D Blakely; Evgeny Bychkov; Carley Siedlecki; Elviche L Tsakem; Eugenia V Gurevich
Cognitive effects of dopamine depletion in the context of diminished acetylcholine signaling capacity in mice.
Disease models & mechanisms 2013;6(1):171-83.
2012: Jerry C Chang; Oleg Kovtun; Randy D Blakely; Sandra J Rosenthal
Labeling of neuronal receptors and transporters with quantum dots.
Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology 2012;4(6):605-19.
2012: Jerry C Chang; David W Piston; Randy D Blakely; Ana M D Carneiro; Ian D Tomlinson; Alessandro Ustione; Michael R Warnement; Sandra J Rosenthal
Single molecule analysis of serotonin transporter regulation using antagonist-conjugated quantum dots reveals restricted, p38 MAPK-dependent mobilization underlying uptake activation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012;32(26):8919-29.
2012: Dhananjay Sakrikar; Jeremy Veenstra-VanderWeele; Erica Bowton; Aurelio Galli; Michael Gill; Peter J Hamilton; Qiao Han; Michelle S Mazei-Robison; Marc A Mergy; Nathan W Richtand; Randy D Blakely
Attention deficit/hyperactivity disorder-derived coding variation in the dopamine transporter disrupts microdomain targeting and trafficking regulation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012;32(16):5385-97.
2012: Jeremy Veenstra-VanderWeele; Ran Ye; Ana Carneiro; Jordan Cohen; Jacqueline N Crawley; Lynette Daws; Hideki Iwamoto; Tammy Jessen; Travis M Kerr; Padmanabhan Mannangatti; Douglas G McMahon; Christopher L Muller; W Anthony Owens; Sammanda Ramamoorthy; Elaine Sanders-Bush; Jennifer E Sauer; Charisma R Shah; James S Sutcliffe; Brent J Thompson; Randy D Blakely
Autism gene variant causes hyperserotonemia, serotonin receptor hypersensitivity, social impairment and repetitive behavior.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(14):5469-74.
2011: R Ye; Randy D Blakely
Natural and engineered coding variation in antidepressant-sensitive serotonin transporters.
Neuroscience 2011;197():28-36.
2011: Jerry C Chang; Louis J DeFelice; Hideki Iwamoto; Ian D Tomlinson; Michael R Warnement; Randy D Blakely; Sandra J Rosenthal
A fluorescence displacement assay for antidepressant drug discovery based on ligand-conjugated quantum dots.
Journal of the American Chemical Society 2011;133(44):17528-31.
2011: Susan L Erickson; Anjalika R Gandhi; Leeann H Miner; Allan R Sampson; Josephine K Asafu-Adjei; Randy D Blakely; Susan R Sesack
Chronic desipramine treatment alters tyrosine hydroxylase but not norepinephrine transporter immunoreactivity in norepinephrine axons in the rat prefrontal cortex.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2011;14(9):1219-32.
2011: Keith Henry; Hideki Iwamoto; Miriam T Jacobs; Kristian Kaufmann; Jens Meiler; Sergei Y Noskov; Gary Rudnick; Ernesto Solis; Igor Zdravkovic; Steven Combs; Eric S Dawson; Louis J DeFelice; Bruce Felts; Julie R Field; Chelsea Adams; Vanessa Armstrong; Randy D Blakely
A conserved asparagine residue in transmembrane segment 1 (TM1) of serotonin transporter dictates chloride-coupled neurotransmitter transport.
The Journal of biological chemistry 2011;286(35):30823-36.
2011: Chong-Bin Zhu; Nicholas G Campbell; William A Hewlett; Kathryn M Lindler; James S Sutcliffe; Randy D Blakely
Colocalization and regulated physical association of presynaptic serotonin transporters with A₃ adenosine receptors.
Molecular pharmacology 2011;80(3):458-65.
2011: Oleg Kovtun; Randy D Blakely; Jerry C Chang; Dhananjay S Sakrikar; Ian D Tomlinson; Sandra J Rosenthal
Visualization of the cocaine-sensitive dopamine transporter with ligand-conjugated quantum dots.
ACS chemical neuroscience 2011;2(7):370-8.
2011: Ian D Tomlinson; Hideki Iwamoto; Randy D Blakely; Sandra J Rosenthal
Biotin tethered homotryptamine derivatives: high affinity probes of the human serotonin transporter (hSERT).
Bioorganic & medicinal chemistry letters 2011;21(6):1678-82.
2010: D Lund; A M Ruggiero; Shawn M Ferguson; Jane Wright; B A English; P A Reisz; S M Whitaker; A C Peltier; Randy D Blakely
Motor neuron-specific overexpression of the presynaptic choline transporter: impact on motor endurance and evoked muscle activity.
Neuroscience 2010;171(4):1041-53.
2010: Zhishan Li; Marc G Caron; Randy D Blakely; Kara G Margolis; Michael D Gershon
Dependence of serotonergic and other nonadrenergic enteric neurons on norepinephrine transporter expression.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(49):16730-40.
2010: Chong-Bin Zhu; Kathryn M Lindler; Anthony W Owens; Lynette Daws; Randy D Blakely; William A Hewlett
Interleukin-1 receptor activation by systemic lipopolysaccharide induces behavioral despair linked to MAPK regulation of CNS serotonin transporters.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2010;35(13):2510-20.
2010: Brett A English; Martin Appalsamy; André Diedrich; Alicia M Ruggiero; David Lund; Jane Wright; Nancy R Keller; Katherine M Louderback; David Robertson; Randy D Blakely
Tachycardia, reduced vagal capacity, and age-dependent ventricular dysfunction arising from diminished expression of the presynaptic choline transporter.
American journal of physiology. Heart and circulatory physiology 2010;299(3):H799-810.
2010: Ericka Causey Holmstrand; Josephine Asafu-Adjei; Allan R Sampson; Randy D Blakely; Susan R Sesack
Ultrastructural localization of high-affinity choline transporter in the rat anteroventral thalamus and ventral tegmental area: differences in axon morphology and transporter distribution.
The Journal of comparative neurology 2010;518(11):1908-24.
2010: Nina Kaludercic; Eiki Takimoto; Takahiro Nagayama; Ning Feng; Edwin W Lai; Djahida Bedja; Kevin Chen; Kathleen L Gabrielson; Randy D Blakely; Jean C Shih; Karel Pacak; David A Kass; Fabio Di Lisa; Nazareno Paolocci
Monoamine oxidase A-mediated enhanced catabolism of norepinephrine contributes to adverse remodeling and pump failure in hearts with pressure overload.
Circulation research 2010;106(1):193-202.
2009: Brett A English; Maureen K Hahn; Ian R Gizer; Michelle Mazei-Robison; Angela Steele; Daniel M Kurnik; Mark Stein; Irwin D Waldman; Randy D Blakely
Choline transporter gene variation is associated with attention-deficit hyperactivity disorder.
Journal of neurodevelopmental disorders 2009;1(4):252-63.
2009: Michael E May; Ali Srour; Lora K Hedges; David A Lightfoot; John A Phillips; Randy D Blakely; Craig H Kennedy
Monoamine oxidase a promoter gene associated with problem behavior in adults with intellectual/developmental disabilities.
American journal on intellectual and developmental disabilities 2009;114(4):269-73.
2009: George M Anderson; Edwin H Cook; Randy D Blakely
Serotonin rising.
The New England journal of medicine 2009;360(24):2580; author reply 2581-2.
2009: V Raj; Kirsten L Haman; Satish R Raj; D Byrne; Randy D Blakely; Italo Biaggioni; David Robertson; Richard C Shelton
Psychiatric profile and attention deficits in postural tachycardia syndrome.
Journal of neurology, neurosurgery, and psychiatry 2009;80(3):339-44.
2009: Kristian W Kaufmann; Eric S Dawson; Keith Henry; Julie R Field; Randy D Blakely; Jens Meiler
Structural determinants of species-selective substrate recognition in human and Drosophila serotonin transporters revealed through computational docking studies.
Proteins 2009;74(3):630-42.
2009: Ana Carneiro; David C Airey; Brent Thompson; Chong-Bin Zhu; Lu Lu; Elissa J Chesler; Keith M Erikson; Randy D Blakely
Functional coding variation in recombinant inbred mouse lines reveals multiple serotonin transporter-associated phenotypes.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(6):2047-52.
2009: Harish C Prasad; Jennifer A Steiner; James S Sutcliffe; Randy D Blakely
Enhanced activity of human serotonin transporter variants associated with autism.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2009;364(1514):163-73.
2009: Jennifer A Steiner; Ana Carneiro; Jane Wright; Heinrich Matthies; Harish C Prasad; Christian K Nicki; Wolfgang R Dostmann; Carrie C Buchanan; Jackie D Corbin; Sharron H Francis; Randy D Blakely
cGMP-dependent protein kinase Ialpha associates with the antidepressant-sensitive serotonin transporter and dictates rapid modulation of serotonin uptake.
Molecular brain 2009;2():26.
2009: Heinrich Matthies; Qiao Han; Angela Shields; Jane Wright; Jessica L Moore; Danny G Winder; Aurelio Galli; Randy D Blakely
Subcellular localization of the antidepressant-sensitive norepinephrine transporter.
BMC neuroscience 2009;10():65.
2008: Jiali Zhao; Dawn Signor Matthies; Emmanuel J Botzolakis; Robert L Macdonald; Randy D Blakely; Peter Hedera
Hereditary spastic paraplegia-associated mutations in the NIPA1 gene and its Caenorhabditis elegans homolog trigger neural degeneration in vitro and in vivo through a gain-of-function mechanism.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(51):13938-51.
2008: Jennifer L Hoard; Donald B Hoover; A M Mabe; Randy D Blakely; N Feng; Nazareno Paolocci
Cholinergic neurons of mouse intrinsic cardiac ganglia contain noradrenergic enzymes, norepinephrine transporters, and the neurotrophin receptors tropomyosin-related kinase A and p75.
Neuroscience 2008;156(1):129-42.
2008: Lucia Carvelli; Randy D Blakely; Louis J DeFelice
Dopamine transporter/syntaxin 1A interactions regulate transporter channel activity and dopaminergic synaptic transmission.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(37):14192-7.
2008: Jennifer A Steiner; Ana Carneiro; Randy D Blakely
Going with the flow: trafficking-dependent and -independent regulation of serotonin transport.
Traffic (Copenhagen, Denmark) 2008;9(9):1393-402.
2008: Michelle S Mazei-Robison; Erica Bowton; Marion Holy; Martin Schmudermaier; Michael Freissmuth; Harald H Sitte; Aurelio Galli; Randy D Blakely
Anomalous dopamine release associated with a human dopamine transporter coding variant.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(28):7040-6.
2008: Hidemi Misawa; Hirofumi Fujigaya; Takashi Nishimura; Yasuhiro Moriwaki; Takashi Okuda; Koichiro Kawashima; Kazuko Nakata; Alicia M Ruggiero; Randy D Blakely; Fubito Nakatsu; Hiroshi Ohno
Aberrant trafficking of the high-affinity choline transporter in AP-3-deficient mice.
The European journal of neuroscience 2008;27(12):3109-17.
2008: Maureen K Hahn; J U Blackford; Kirsten L Haman; M Mazei-Robison; B A English; H C Prasad; A Steele; L Hazelwood; H M Fentress; R Myers; Randy D Blakely; E Sanders-Bush; R Shelton
Multivariate permutation analysis associates multiple polymorphisms with subphenotypes of major depression.
Genes, brain, and behavior 2008;7(4):487-95.
2008: Ana Carneiro; Edwin H Cook; Dennis L Murphy; Randy D Blakely
Interactions between integrin alphaIIbbeta3 and the serotonin transporter regulate serotonin transport and platelet aggregation in mice and humans.
The Journal of clinical investigation 2008;118(4):1544-52.
2008: Rebecca L Orndorff; Michael R Warnement; John N Mason; Randy D Blakely; Sandra J Rosenthal
Quantum dot ex vivo labeling of neuromuscular synapses.
Nano letters 2008;8(3):780-5.
2008: Keith Henry; Randy D Blakely
Distinctions between dopamine transporter antagonists could be just around the bend.
Molecular pharmacology 2008;73(3):616-8.
2008: Chun-Hyung Kim; Irwin D Waldman; Randy D Blakely; Kwang-Soo Kim
Functional gene variation in the human norepinephrine transporter: association with attention deficit hyperactivity disorder.
Annals of the New York Academy of Sciences 2008;1129():256-60.
2007: Paul W McDonald; Shannon L Hardie; Tammy Jessen; Lucia Carvelli; Dawn Signor Matthies; Randy D Blakely
Vigorous motor activity in Caenorhabditis elegans requires efficient clearance of dopamine mediated by synaptic localization of the dopamine transporter DAT-1.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(51):14216-27.
2007: Keith Henry; Jens Meiler; Randy D Blakely
Bound to be different: neurotransmitter transporters meet their bacterial cousins.
Molecular interventions 2007;7(6):306-9.
2007: John N Mason; Darlene C Deecher; Rhonda L Richmond; Gary Stack; Paige E Mahaney; Eugene Trybulski; Richard Winneker; Randy D Blakely
Desvenlafaxine succinate identifies novel antagonist binding determinants in the human norepinephrine transporter.
The Journal of pharmacology and experimental therapeutics 2007;323(2):720-9.
2007: Jason Williams; W Anthony Owens; Gregory Turner; Christine Saunders; Concetta Dipace; Randy D Blakely; Charles France; John C Gore; Lynette Daws; Malcolm J Avison; Aurelio Galli
Hypoinsulinemia regulates amphetamine-induced reverse transport of dopamine.
PLoS biology 2007;5(10):e274.
2007: Ian D Tomlinson; Michael R Warnerment; John N Mason; Matthew J Vergne; David M Hercules; Randy D Blakely; Sandra J Rosenthal
Synthesis and characterization of a pegylated derivative of 3-(1,2,3,6-tetrahydro-pyridin-4yl)-1H-indole (IDT199): a high affinity SERT ligand for conjugation to quantum dots.
Bioorganic & medicinal chemistry letters 2007;17(20):5656-60.
2007: Chong-Bin Zhu; Jennifer A Steiner; Jaclyn L Munn; Lynette Daws; William A Hewlett; Randy D Blakely
Rapid stimulation of presynaptic serotonin transport by A(3) adenosine receptors.
The Journal of pharmacology and experimental therapeutics 2007;322(1):332-40.
2007: Mihaela Bazalakova; Jane Wright; E J Schneble; Michael P McDonald; C J Heilman; Allan Levey; Randy D Blakely
Deficits in acetylcholine homeostasis, receptors and behaviors in choline transporter heterozygous mice.
Genes, brain, and behavior 2007;6(5):411-24.
2007: Randy D Blakely; Louis J DeFelice
All aglow about presynaptic receptor regulation of neurotransmitter transporters.
Molecular pharmacology 2007;71(5):1206-8.
2007: Uhna Sung; Randy D Blakely
Calcium-dependent interactions of the human norepinephrine transporter with syntaxin 1A.
Molecular and cellular neurosciences 2007;34(2):251-60.
2007: Manfred G Ismair; Gerd A Kullak-Ublick; Randy D Blakely; Michael Fried; Stephan R Vavricka
Tegaserod inhibits the serotonin transporter SERT.
Digestion 2007;75(2-3):90-5.
2007: Adam M Wegner; Jamie L McConnell; Randy D Blakely; Brian E Wadzinski
An automated fluorescence-based method for continuous assay of PP2A activity.
Methods in molecular biology (Clifton, N.J.) 2007;365():61-9.
2007: Maureen K Hahn; Randy D Blakely
The functional impact of SLC6 transporter genetic variation.
Annual review of pharmacology and toxicology 2007;47():401-41.
2007: Concetta Dipace; Uhna Sung; Francesca Binda; Randy D Blakely; Aurelio Galli
Amphetamine induces a calcium/calmodulin-dependent protein kinase II-dependent reduction in norepinephrine transporter surface expression linked to changes in syntaxin 1A/transporter complexes.
Molecular pharmacology 2007;71(1):230-9.
2006: Chun-Hyung Kim; Maureen K Hahn; Yoosook Joung; Susan L Anderson; Angela H Steele; Michelle S Mazei-Robinson; Ian Gizer; Martin H Teicher; Bruce M Cohen; David Robertson; Irwin D Waldman; Randy D Blakely; Kwang-Soo Kim
A polymorphism in the norepinephrine transporter gene alters promoter activity and is associated with attention-deficit hyperactivity disorder.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(50):19164-9.
2006: Chong-Bin Zhu; Randy D Blakely; William A Hewlett
The proinflammatory cytokines interleukin-1beta and tumor necrosis factor-alpha activate serotonin transporters.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2006;31(10):2121-31.
2006: Hideki Iwamoto; Randy D Blakely; Louis J De Felice
Na+, Cl-, and pH dependence of the human choline transporter (hCHT) in Xenopus oocytes: the proton inactivation hypothesis of hCHT in synaptic vesicles.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(39):9851-9.
2006: Ian D Tomlinson; John N Mason; Randy D Blakely; Sandra J Rosenthal
High affinity inhibitors of the dopamine transporter (DAT): novel biotinylated ligands for conjugation to quantum dots.
Bioorganic & medicinal chemistry letters 2006;16(17):4664-7.
2006: Ana Carneiro; Randy D Blakely
Serotonin-, protein kinase C-, and Hic-5-associated redistribution of the platelet serotonin transporter.
The Journal of biological chemistry 2006;281(34):24769-80.
2006: Paul W McDonald; Tammy Jessen; Julie R Field; Randy D Blakely
Dopamine signaling architecture in Caenorhabditis elegans.
Cellular and molecular neurobiology 2006;26(4-6):593-618.
2006: Dawn Signor Matthies; Paul A Fleming; Don M Wilkes; Randy D Blakely
The Caenorhabditis elegans choline transporter CHO-1 sustains acetylcholine synthesis and motor function in an activity-dependent manner.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(23):6200-12.
2006: Keith Henry; Louis J DeFelice; Randy D Blakely
Getting the message across: a recent transporter structure shows the way.
Neuron 2006;49(6):791-6.
2006: Francesca Binda; Brandon J Lute; Concetta Dipace; Randy D Blakely; Aurelio Galli
The N-terminus of the norepinephrine transporter regulates the magnitude and selectivity of the transporter-associated leak current.
Neuropharmacology 2006;50(3):354-61.
2006: Leeann H Miner; Hank P Jedema; Forrest W Moore; Randy D Blakely; Anthony A Grace; Susan R Sesack
Chronic stress increases the plasmalemmal distribution of the norepinephrine transporter and the coexpression of tyrosine hydroxylase in norepinephrine axons in the prefrontal cortex.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(5):1571-8.
2006: Keith Henry; Julie R Field; Erika Adkins Scholl; M Laura Parnas; Roxanne A Vaughan; Mu-Fa Zou; Amy Hauck Newman; Randy D Blakely
Tyr-95 and Ile-172 in transmembrane segments 1 and 3 of human serotonin transporters interact to establish high affinity recognition of antidepressants.
The Journal of biological chemistry 2006;281(4):2012-23.
2006: M H Bazalakova; Randy D Blakely
The high-affinity choline transporter: a critical protein for sustaining cholinergic signaling as revealed in studies of genetically altered mice.
Handbook of experimental pharmacology 2006;(175):525-44.
2006: M S Mazei-Robinson; Randy D Blakely
ADHD and the dopamine transporter: are there reasons to pay attention?
Handbook of experimental pharmacology 2006;(175):373-415.
2006: Nancy R Keller; André Diedrich; Martin Appalsamy; L C Miller; Marc G Caron; Michael P McDonald; Richard C Shelton; Randy D Blakely; David Robertson
Norepinephrine transporter-deficient mice respond to anxiety producing and fearful environments with bradycardia and hypotension.
Neuroscience 2006;139(3):931-46.
2005: GL Guidry; Breanne D Willison; Randy D Blakely; Story C Landis; Beth A Habecker
Developmental expression of the high affinity choline transporter in cholinergic sympathetic neurons.
Autonomic neuroscience : basic & clinical 2005;123(1-2):54-61.
2005: Randy D Blakely
Overview: a rare opportunity or just one less reason to be depressed.
Neuron 2005;48(5):701-2; author reply 705-6.
2005: Ian D Tomlinson; John N Mason; Randy D Blakely; Sandra J Rosenthal
Inhibitors of the serotonin transporter protein (SERT): the design and synthesis of biotinylated derivatives of 3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indoles. High-affinity serotonergic ligands for conjugation with quantum dots.
Bioorganic & medicinal chemistry letters 2005;15(23):5307-10.
2005: Elizabeth L Bentzen; Ian D Tomlinson; John Mason; Paul J Gresch; Michael R Warnement; David Wright; Elaine Sanders-Bush; Randy D Blakely; Sandra J Rosenthal
Surface modification to reduce nonspecific binding of quantum dots in live cell assays.
Bioconjugate chemistry 2005;16(6):1488-94.
2005: Michelle S Mazei-Robison; Randy D Blakely
Expression studies of naturally occurring human dopamine transporter variants identifies a novel state of transporter inactivation associated with Val382Ala.
Neuropharmacology 2005;49(6):737-49.
2005: Michelle S Mazei-Robison; R Steven Couch; Richard C Shelton; Mark Stein; Randy D Blakely
Sequence variation in the human dopamine transporter gene in children with attention deficit hyperactivity disorder.
Neuropharmacology 2005;49(6):724-36.
2005: Harish C Prasad; Chong-Bin Zhu; Jacob McCauley; Devadoss J Samuvel; Sammanda Ramamoorthy; Richard C Shelton; William A Hewlett; James S Sutcliffe; Randy D Blakely
Human serotonin transporter variants display altered sensitivity to protein kinase G and p38 mitogen-activated protein kinase.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(32):11545-50.
2005: Uhna Sung; Jennifer L Jennings; Andrew J Link; Randy D Blakely
Proteomic analysis of human norepinephrine transporter complexes reveals associations with protein phosphatase 2A anchoring subunit and 14-3-3 proteins.
Biochemical and biophysical research communications 2005;333(3):671-8.
2005: Randy D Blakely; Louis J Defelice; Aurelio Galli
Biogenic amine neurotransmitter transporters: just when you thought you knew them.
Physiology (Bethesda, Md.) 2005;20():225-31.
2005: James S Sutcliffe; Ryan J Delahanty; Harish C Prasad; Jacob McCauley; Qiao Han; Lan Jiang; Chun Li; Susan E Folstein; Randy D Blakely
Allelic heterogeneity at the serotonin transporter locus (SLC6A4) confers susceptibility to autism and rigid-compulsive behaviors.
American journal of human genetics 2005;77(2):265-79.
2005: Richard Nass; Maureen K Hahn; Tammy Jessen; Paul W McDonald; Lucia Carvelli; Randy D Blakely
A genetic screen in Caenorhabditis elegans for dopamine neuron insensitivity to 6-hydroxydopamine identifies dopamine transporter mutants impacting transporter biosynthesis and trafficking.
Journal of neurochemistry 2005;94(3):774-85.
2005: Maureen K Hahn; Michelle S Mazei-Robison; Randy D Blakely
Single nucleotide polymorphisms in the human norepinephrine transporter gene affect expression, trafficking, antidepressant interaction, and protein kinase C regulation.
Molecular pharmacology 2005;68(2):457-66.
2005: Elizabeth J Meredith; Michelle J Holder; Anita Chamba; Anita Challa; Adrian Drake-Lee; Christopher M Bunce; Mark T Drayson; Geoffrey Pilkington; Randy D Blakely; Martin J S Dyer; Nicholas M Barnes; John Gordon
The serotonin transporter (SLC6A4) is present in B-cell clones of diverse malignant origin: probing a potential anti-tumor target for psychotropics.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(9):1187-9.
2005: Lankupalle D Jayanthi; Devadoss J Samuvel; Randy D Blakely; Sammanda Ramamoorthy
Evidence for biphasic effects of protein kinase C on serotonin transporter function, endocytosis, and phosphorylation.
Molecular pharmacology 2005;67(6):2077-87.
2005: Chong-Bin Zhu; Ana Carneiro; Wolfgang R Dostmann; William A Hewlett; Randy D Blakely
p38 MAPK activation elevates serotonin transport activity via a trafficking-independent, protein phosphatase 2A-dependent process.
The Journal of biological chemistry 2005;280(16):15649-58.
2005: John N Mason; H Farmer; Ian D Tomlinson; Joel W Schwartz; Valentina Savchenko; Louis J DeFelice; Sandra J Rosenthal; Randy D Blakely
Novel fluorescence-based approaches for the study of biogenic amine transporter localization, activity, and regulation.
Journal of neuroscience methods 2005;143(1):3-25.
2005: Regula E Egli; Thomas Kash; Kevin Choo; Valentina Savchenko; Robert T Matthews; Randy D Blakely; Danny G Winder
Norepinephrine modulates glutamatergic transmission in the bed nucleus of the stria terminalis.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2005;30(4):657-68.
2005: Kristopher M Kahlig; Francesca Binda; Habibeh Khoshbouei; Randy D Blakely; Douglas G McMahon; Jonathan A Javitch; Aurelio Galli
Amphetamine induces dopamine efflux through a dopamine transporter channel.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(9):3495-500.
2005: Takahiro Fukumoto; Randy D Blakely; Michael Levin
Serotonin transporter function is an early step in left-right patterning in chick and frog embryos.
Developmental neuroscience 2005;27(6):349-63.
2005: Ian D Tomlinson; John N Mason; Randy D Blakely; Sandra J Rosenthal
Peptide-conjugated quantum dots: imaging the angiotensin type 1 receptor in living cells.
Methods in molecular biology (Clifton, N.J.) 2005;303():51-60.
2005: John N Mason; Ian D Tomlinson; Sandra J Rosenthal; Randy D Blakely
Labeling cell-surface proteins via antibody quantum dot streptavidin conjugates.
Methods in molecular biology (Clifton, N.J.) 2005;303():35-50.
2004: Lucia Carvelli; Paul W McDonald; Randy D Blakely; Louis J DeFelice
Dopamine transporters depolarize neurons by a channel mechanism.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(45):16046-51.
2004: Chong-Bin Zhu; William A Hewlett; Sharron H Francis; Jackie D Corbin; Randy D Blakely
Stimulation of serotonin transport by the cyclic GMP phosphodiesterase-5 inhibitor sildenafil.
European journal of pharmacology 2004;504(1-2):1-6.
2004: Jeremiah Gates; Shawn M Ferguson; Randy D Blakely; Subbu Apparsundaram
Regulation of choline transporter surface expression and phosphorylation by protein kinase C and protein phosphatase 1/2A.
The Journal of pharmacology and experimental therapeutics 2004;310(2):536-45.
2004: Lindsay A Liprando; Leeann H Miner; Randy D Blakely; David A Lewis; Susan R Sesack
Ultrastructural interactions between terminals expressing the norepinephrine transporter and dopamine neurons in the rat and monkey ventral tegmental area.
Synapse (New York, N.Y.) 2004;52(4):233-44.
2004: Shawn M Ferguson; Mihaela Bazalakova; Valentina Savchenko; Juan Carlos Tapia; Jane Wright; Randy D Blakely
Lethal impairment of cholinergic neurotransmission in hemicholinium-3-sensitive choline transporter knockout mice.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(23):8762-7.
2004: Chong-Bin Zhu; William A Hewlett; Igor Feoktistov; Italo Biaggioni; Randy D Blakely
Adenosine receptor, protein kinase G, and p38 mitogen-activated protein kinase-dependent up-regulation of serotonin transporters involves both transporter trafficking and activation.
Molecular pharmacology 2004;65(6):1462-74.
2004: Jacob McCauley; Lana M Olson; Michael Dowd; Taneem Amin; A Steele; Randy D Blakely; Susan E Folstein; Jonathan L Haines; James S Sutcliffe
Linkage and association analysis at the serotonin transporter (SLC6A4) locus in a rigid-compulsive subset of autism.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2004;127B(1):104-12.
2004: Becky J Proskocil; Harmanjatinder S Sekhon; Yibing Jia; Valentina Savchenko; Randy D Blakely; Jon Lindstrom; Eliot R Spindel
Acetylcholine is an autocrine or paracrine hormone synthesized and secreted by airway bronchial epithelial cells.
Endocrinology 2004;145(5):2498-506.
2004: Donald B Hoover; Charles E Ganote; Shawn M Ferguson; Randy D Blakely; Rodney L Parsons
Localization of cholinergic innervation in guinea pig heart by immunohistochemistry for high-affinity choline transporters.
Cardiovascular research 2004;62(1):112-21.
2004: Shawn M Ferguson; Randy D Blakely
The choline transporter resurfaces: new roles for synaptic vesicles?
Molecular interventions 2004;4(1):22-37.
2003: Valentina Savchenko; Uhna Sung; Randy D Blakely
Cell surface trafficking of the antidepressant-sensitive norepinephrine transporter revealed with an ectodomain antibody.
Molecular and cellular neurosciences 2003;24(4):1131-50.
2003: Laura A Volpicelli-Daley; Anna Hrabovska; Ellen G Duysen; Shawn M Ferguson; Randy D Blakely; Oksana Lockridge; Allan Levey
Altered striatal function and muscarinic cholinergic receptors in acetylcholinesterase knockout mice.
Molecular pharmacology 2003;64(6):1309-16.
2003: Leeann H Miner; Sally Schroeter; Randy D Blakely; Susan R Sesack
Ultrastructural localization of the norepinephrine transporter in superficial and deep layers of the rat prelimbic prefrontal cortex and its spatial relationship to probable dopamine terminals.
The Journal of comparative neurology 2003;466(4):478-94.
2003: Shawn M Ferguson; Valentina Savchenko; Subbu Apparsundaram; Melissa Zwick; Jane Wright; Craig J Heilman; Hong Yi; Allan Levey; Randy D Blakely
Vesicular localization and activity-dependent trafficking of presynaptic choline transporters.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(30):9697-709.
2003: Keith Henry; Erika Adkins Scholl; Qiao Han; Randy D Blakely
Serotonin and cocaine-sensitive inactivation of human serotonin transporters by methanethiosulfonates targeted to transmembrane domain I.
The Journal of biological chemistry 2003;278(39):37052-63.
2003: Laura Kus; Ewa Borys; Ya Ping Chu; Shawn M Ferguson; Randy D Blakely; Marina E Emborg; Jeffrey Kordower; Allan Levey; Elliott J Mufson
Distribution of high affinity choline transporter immunoreactivity in the primate central nervous system.
The Journal of comparative neurology 2003;463(3):341-57.
2003: Merja Lakso; Suvi Vartiainen; Anu-Maarit Moilanen; Jouni Sirviö; James H Thomas; Richard Nass; Randy D Blakely; Garry Wong
Dopaminergic neuronal loss and motor deficits in Caenorhabditis elegans overexpressing human alpha-synuclein.
Journal of neurochemistry 2003;86(1):165-72.
2003: Maureen K Hahn; David Robertson; Randy D Blakely
A mutation in the human norepinephrine transporter gene (SLC6A2) associated with orthostatic intolerance disrupts surface expression of mutant and wild-type transporters.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(11):4470-8.
2003: Twum-Ampofo Ansah; Sammanda Ramamoorthy; Sylvia Montañez; Lynette Daws; Randy D Blakely
Calcium-dependent inhibition of synaptosomal serotonin transport by the alpha 2-adrenoceptor agonist 5-bromo-N-[4,5-dihydro-1H-imidazol-2-yl]-6-quinoxalinamine (UK14304).
The Journal of pharmacology and experimental therapeutics 2003;305(3):956-65.
2003: Joel W Schwartz; Randy D Blakely; Louis J DeFelice
Binding and transport in norepinephrine transporters. Real-time, spatially resolved analysis in single cells using a fluorescent substrate.
The Journal of biological chemistry 2003;278(11):9768-77.
2003: Uhna Sung; Subbu Apparsundaram; Aurelio Galli; Kristopher M Kahlig; Valentina Savchenko; Sally Schroeter; Michael W Quick; Randy D Blakely
A regulated interaction of syntaxin 1A with the antidepressant-sensitive norepinephrine transporter establishes catecholamine clearance capacity.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(5):1697-709.
2003: Richard Nass; Randy D Blakely
The Caenorhabditis elegans dopaminergic system: opportunities for insights into dopamine transport and neurodegeneration.
Annual review of pharmacology and toxicology 2003;43():521-44.
2002: Emily M Garland; Maureen K Hahn; Terry Ketch; Nancy R Keller; Chun-Hyung Kim; Kwang-Soo Kim; Italo Biaggioni; John R Shannon; Randy D Blakely; David Robertson
Genetic basis of clinical catecholamine disorders.
Annals of the New York Academy of Sciences 2002;971():506-14.
2002: Carol A Tamminga; Charles Nemeroff; Randy D Blakely; Linda Brady; Cameron S Carter; Kenneth L Davis; ray dingledine; Jack M Gorman; Dimitri E Grigoriadis; David C Henderson; Robert B B Innis; John Killen; Thomas Laughren; William M McDonald; Greer M M Murphy; Steven M Paul; Matthew V Rudorfer; Edward A Sausville; Alan F Schatzberg; Edward M Scolnick; Trisha Suppes
Developing novel treatments for mood disorders: accelerating discovery.
Biological psychiatry 2002;52(6):589-609.
2002: Patricia A Bauman; Randy D Blakely
Determinants within the C-terminus of the human norepinephrine transporter dictate transporter trafficking, stability, and activity.
Archives of biochemistry and biophysics 2002;404(1):80-91.
2002: Sandra J Rosenthal; Ian Tomlinson; Erika Adkins Scholl; Sally Schroeter; Scott Adams; Laura Swafford; James McBride; Yongqiang Wang; Louis J DeFelice; Randy D Blakely
Targeting cell surface receptors with ligand-conjugated nanocrystals.
Journal of the American Chemical Society 2002;124(17):4586-94.
2002: Adamantios Serafeim; Gillian Grafton; Anita Chamba; Christopher D Gregory; Randy D Blakely; Norman G Bowery; Nicholas M Barnes; John Gordon
5-Hydroxytryptamine drives apoptosis in biopsylike Burkitt lymphoma cells: reversal by selective serotonin reuptake inhibitors.
Blood 2002;99(7):2545-53.
2002: Richard Nass; David H Hall; David M Miller; Randy D Blakely
Neurotoxin-induced degeneration of dopamine neurons in Caenorhabditis elegans.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(5):3264-9.
2002: Maureen K Hahn; Randy D Blakely
Monoamine transporter gene structure and polymorphisms in relation to psychiatric and other complex disorders.
The pharmacogenomics journal 2002;2(4):217-35.
2001: Subbu Apparsundaram; Shawn M Ferguson; Randy D Blakely
Molecular cloning and characterization of a murine hemicholinium-3-sensitive choline transporter.
Biochemical Society transactions 2001;29(Pt 6):711-6.
2001: Randy D Blakely
Physiological genomics of antidepressant targets: keeping the periphery in mind.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(21):8319-23.
2001: Subbu Apparsundaram; Uhna Sung; Raymond Price; Randy D Blakely
Trafficking-dependent and -independent pathways of neurotransmitter transporter regulation differentially involving p38 mitogen-activated protein kinase revealed in studies of insulin modulation of norepinephrine transport in SK-N-SH cells.
The Journal of pharmacology and experimental therapeutics 2001;299(2):666-77.
2001: Randy D Blakely
Neurobiology. Dopamine's reversal of fortune.
Science (New York, N.Y.) 2001;293(5539):2407-9.
2001: David Robertson; NL Flattem; T Tellioglu; Robert Carson; Emily M Garland; John R Shannon; Jens Jordan; Giris Jacob; Randy D Blakely; Italo Biaggioni
Familial orthostatic tachycardia due to norepinephrine transporter deficiency.
Annals of the New York Academy of Sciences 2001;940():527-43.
2001: AR Belous; Sammanda Ramamoorthy; Randy D Blakely; Magnolia I Factor; AM Dupin; AB Katasonov; R H Lozier; AG Beniashvili; Margarita A Morozova; Oleg S Brusov
The state of the serotonin transporter protein in the platelets of patients with somatoform [correction of somatiform] disorders.
Neuroscience and behavioral physiology 2001;31(2):185-9.
2001: ZG Ren; PP Pörzgen; Jianmin Zhang; X R Chen; Susan Amara; Randy D Blakely; Maya Sieber-Blum
Autocrine regulation of norepinephrine transporter expression.
Molecular and cellular neurosciences 2001;17(3):539-50.
2001: Erika Adkins Scholl; Eric L Barker; Randy D Blakely
Interactions of tryptamine derivatives with serotonin transporter species variants implicate transmembrane domain I in substrate recognition.
Molecular pharmacology 2001;59(3):514-23.
2000: Leeann H Miner; Sally Schroeter; Randy D Blakely; Susan R Sesack
Ultrastructural localization of the serotonin transporter in superficial and deep layers of the rat prelimbic prefrontal cortex and its spatial relationship to dopamine terminals.
The Journal of comparative neurology 2000;427(2):220-34.
2000: Andrea L Bauman; Subbu Apparsundaram; Sammanda Ramamoorthy; Brian E Wadzinski; Roxanne A Vaughan; Randy D Blakely
Cocaine and antidepressant-sensitive biogenic amine transporters exist in regulated complexes with protein phosphatase 2A.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(20):7571-8.
2000: Subbu Apparsundaram; Shawn M Ferguson; Alfred L George; Randy D Blakely
Molecular cloning of a human, hemicholinium-3-sensitive choline transporter.
Biochemical and biophysical research communications 2000;276(3):862-7.
2000: Randy D Blakely; U Sung
SNARE-ing neurotransmitter transporters.
Nature neuroscience 2000;3(10):969-71.
2000: Randy D Blakely; Andrea L Bauman
Biogenic amine transporters: regulation in flux.
Current opinion in neurobiology 2000;10(3):328-36.
2000: Sally Schroeter; Subbu Apparsundaram; R G Wiley; Leeann H Miner; Susan R Sesack; Randy D Blakely
Immunolocalization of the cocaine- and antidepressant-sensitive l-norepinephrine transporter.
The Journal of comparative neurology 2000;420(2):211-32.
2000: Fariborz R Rakhshan; T A Day; Randy D Blakely; Eric L Barker
Carrier-mediated uptake of the endogenous cannabinoid anandamide in RBL-2H3 cells.
The Journal of pharmacology and experimental therapeutics 2000;292(3):960-7.
2000: John R Shannon; NL Flattem; Jens Jordan; Giris Jacob; Bonnie K Black; Italo Biaggioni; Randy D Blakely; David Robertson
Orthostatic intolerance and tachycardia associated with norepinephrine-transporter deficiency.
The New England journal of medicine 2000;342(8):541-9.
2000: NL Flattem; Randy D Blakely
Modified structure of the human serotonin transporter promoter.
Molecular psychiatry 2000;5(1):110-5.
1999: AL Upton; N Salichon; Cecile Lebrand; Anne Ravary; Randy D Blakely; Isabelle Seif; patricia Gaspar
Excess of serotonin (5-HT) alters the segregation of ispilateral and contralateral retinal projections in monoamine oxidase A knock-out mice: possible role of 5-HT uptake in retinal ganglion cells during development.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(16):7007-24.
1999: Sammanda Ramamoorthy; Randy D Blakely
Phosphorylation and sequestration of serotonin transporters differentially modulated by psychostimulants.
Science (New York, N.Y.) 1999;285(5428):763-6.
1999: David Robertson; Italo Biaggioni; Andrew Ertl; Rose Marie Robertson; André Diedrich; Randy D Blakely; NL Flattem; John R Shannon
Orthostatic intolerance: emerging genetic and environmental etiologies.
Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology 1999;6(1):P51-4.
1999: Eric L Barker; K R Moore; Fariborz R Rakhshan; Randy D Blakely
Transmembrane domain I contributes to the permeation pathway for serotonin and ions in the serotonin transporter.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(12):4705-17.
1999: AR Belous; S Ramamoothy; Randy D Blakely; MI Faktor; RKh Lozier; AM Dupin; A G Bechiashvili; Margarita A Morozova; Oleg S Brusov
[Decrease in the platelet level of 43 kDa immunoreactive fraction of serotonin transporting protein correlates with depressive symptoms in patients with somatoform disorders].
Voprosy medit͡sinskoĭ khimii 1999;45(3):256-62.
1999: M Tatsumi; K Jansen; Randy D Blakely; Elliott Richelson
Pharmacological profile of neuroleptics at human monoamine transporters.
European journal of pharmacology 1999;368(2-3):277-83.
1999: B Leitner; Paola Lovisetti-Scamihorn; J Heilmann; Jörg Striessnig; Randy D Blakely; L E Eiden; H Winkler
Subcellular localization of chromogranins, calcium channels, amine carriers, and proteins of the exocytotic machinery in bovine splenic nerve.
Journal of neurochemistry 1999;72(3):1110-6.
1999: AR Belous; S Rammamoorthy; Randy D Blakely; Magnolia I Factor; AM Dupin; AB Katasonov; RKh Lozier; AG Beniashvili; Margarita A Morozova; Oleg S Brusov
[The status of serotonin protein -- a serotonin transporter in thrombocytes in patients with somatoform disorders].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova / Ministerstvo zdravookhraneniia i meditsinskoĭ promyshlennosti Rossiĭskoĭ Federatsii, Vserossiĭskoe obshchestvo nevrologov [i] Vserossiĭskoe obshchestvo psikhiatrov 1999;99(11):32-5.
1998: Cecile Lebrand; Olivier Cases; Rosine Wehrlé; Randy D Blakely; Robert H Edwards; patricia Gaspar
Transient developmental expression of monoamine transporters in the rodent forebrain.
The Journal of comparative neurology 1998;401(4):506-24.
1998: Subbu Apparsundaram; Sally Schroeter; E Giovanetti; Randy D Blakely
Acute regulation of norepinephrine transport: II. PKC-modulated surface expression of human norepinephrine transporter proteins.
The Journal of pharmacology and experimental therapeutics 1998;287(2):744-51.
1998: Subbu Apparsundaram; Aurelio Galli; Louis J DeFelice; H Criss Hartzell; Randy D Blakely
Acute regulation of norepinephrine transport: I. protein kinase C-linked muscarinic receptors influence transport capacity and transporter density in SK-N-SH cells.
The Journal of pharmacology and experimental therapeutics 1998;287(2):733-43.
1998: Aurelio Galli; Randy D Blakely; Louis J DeFelice
Patch-clamp and amperometric recordings from norepinephrine transporters: channel activity and voltage-dependent uptake.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(22):13260-5.
1998: Lankupalle D Jayanthi; Subbu Apparsundaram; M D Malone; E Ward; D M Miller; M Eppler; Randy D Blakely
The Caenorhabditis elegans gene T23G5.5 encodes an antidepressant- and cocaine-sensitive dopamine transporter.
Molecular pharmacology 1998;54(4):601-9.
1998: Randy D Blakely; Sammanda Ramamoorthy; Sally Schroeter; Y Qian; Subbu Apparsundaram; Aurelio Galli; Louis J DeFelice
Regulated phosphorylation and trafficking of antidepressant-sensitive serotonin transporter proteins.
Biological psychiatry 1998;44(3):169-78.
1998: Eric L Barker; M A Perlman; Erika Adkins Scholl; W J Houlihan; Zdenek Pristupa; Hyman B Niznik; Randy D Blakely
High affinity recognition of serotonin transporter antagonists defined by species-scanning mutagenesis. An aromatic residue in transmembrane domain I dictates species-selective recognition of citalopram and mazindol.
The Journal of biological chemistry 1998;273(31):19459-68.
1998: JD Fritz; Lankupalle D Jayanthi; Molly A Thoreson; Randy D Blakely
Cloning and chromosomal mapping of the murine norepinephrine transporter.
Journal of neurochemistry 1998;70(6):2241-51.
1998: Meng-Yang Zhu; Randy D Blakely; S Apparsundaram; Gregory A Ordway
Down-regulation of the human norepinephrine transporter in intact 293-hNET cells exposed to desipramine.
Journal of neurochemistry 1998;70(4):1547-55.
1998: Sammanda Ramamoorthy; E Giovanetti; Y Qian; Randy D Blakely
Phosphorylation and regulation of antidepressant-sensitive serotonin transporters.
The Journal of biological chemistry 1998;273(4):2458-66.
1998: Eric L Barker; Randy D Blakely
Structural determinants of neurotransmitter transport using cross-species chimeras: studies on serotonin transporter.
Methods in enzymology 1998;296():475-98.
1998: Sammanda Ramamoorthy; H E Melikian; Y Qian; Randy D Blakely
Biosynthesis, N-glycosylation, and surface trafficking of biogenic amine transporter proteins.
Methods in enzymology 1998;296():347-70.
1998: Randy D Blakely; Subbu Apparsundaram
Structural diversity in the catecholamine transporter gene family: molecular cloning and characterization of an L-epinephrine transporter from bullfrog sympathetic ganglia.
Advances in pharmacology (San Diego, Calif.) 1998;42():206-10.
1998: Joseph B Justice; K S Danek; J W Kable; E L Barker; Randy D Blakely
Voltammetric approaches to kinetics and mechanism of the norepinephrine transporter.
Advances in pharmacology (San Diego, Calif.) 1998;42():191-4.
1997: M Tatsumi; K Groshan; Randy D Blakely; Elliott Richelson
Pharmacological profile of antidepressants and related compounds at human monoamine transporters.
European journal of pharmacology 1997;340(2-3):249-58.
1997: Amy J Eshleman; E Stewart; A K Evenson; John N Mason; Randy D Blakely; Aaron Janowsky; Kim A Neve
Metabolism of catecholamines by catechol-O-methyltransferase in cells expressing recombinant catecholamine transporters.
Journal of neurochemistry 1997;69(4):1459-66.
1997: C C Bradley; Randy D Blakely
Alternative splicing of the human serotonin transporter gene.
Journal of neurochemistry 1997;69(4):1356-67.
1997: Teresa Steininger; B H Wainer; Randy D Blakely; D B Rye
Serotonergic dorsal raphe nucleus projections to the cholinergic and noncholinergic neurons of the pedunculopontine tegmental region: a light and electron microscopic anterograde tracing and immunohistochemical study.
The Journal of comparative neurology 1997;382(3):302-22.
1997: Aurelio Galli; Christina I Petersen; M deBlaquiere; Randy D Blakely; Louis J DeFelice
Drosophila serotonin transporters have voltage-dependent uptake coupled to a serotonin-gated ion channel.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(10):3401-11.
1997: Subbu Apparsundaram; K R Moore; M D Malone; H Criss Hartzell; Randy D Blakely
Molecular cloning and characterization of an L-epinephrine transporter from sympathetic ganglia of the bullfrog, Rana catesbiana.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(8):2691-702.
1997: Sally Schroeter; Allan Levey; Randy D Blakely
Polarized expression of the antidepressant-sensitive serotonin transporter in epinephrine-synthesizing chromaffin cells of the rat adrenal gland.
Molecular and cellular neurosciences 1997;9(3):170-84.
1997: Y Qian; Aurelio Galli; Sammanda Ramamoorthy; S Risso; Louis J DeFelice; Randy D Blakely
Protein kinase C activation regulates human serotonin transporters in HEK-293 cells via altered cell surface expression.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(1):45-57.
1996: Albert S Chang; S M Chang; D M Starnes; Sally Schroeter; Andrea L Bauman; Randy D Blakely
Cloning and expression of the mouse serotonin transporter.
Brain research. Molecular brain research 1996;43(1-2):185-92.
1996: Sally Schroeter; Randy D Blakely
Drug targets in the embryo. Studies on the cocaine- and antidepressant-sensitive serotonin transporter.
Annals of the New York Academy of Sciences 1996;801():239-55.
1996: Eric L Barker; Randy D Blakely
Identification of a single amino acid, phenylalanine 586, that is responsible for high affinity interactions of tricyclic antidepressants with the human serotonin transporter.
Molecular pharmacology 1996;50(4):957-65.
1996: H Tamir; S C Hsiung; K P Liu; Randy D Blakely; Andrew F Russo; M S Clark; E A Nunez; Michael D Gershon
Expression and development of a functional plasmalemmal 5-hydroxytryptamine transporter by thyroid follicular cells.
Endocrinology 1996;137(10):4475-86.
1996: W B Burnette; M D Bailey; S Kukoyi; Randy D Blakely; C G Trowbridge; Joseph B Justice
Human norepinephrine transporter kinetics using rotating disk electrode voltammetry.
Analytical chemistry 1996;68(17):2932-8.
1996: Aurelio Galli; Randy D Blakely; Louis J DeFelice
Norepinephrine transporters have channel modes of conduction.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(16):8671-6.
1996: H E Melikian; Sammanda Ramamoorthy; Christopher G Tate; Randy D Blakely
Inability to N-glycosylate the human norepinephrine transporter reduces protein stability, surface trafficking, and transport activity but not ligand recognition.
Molecular pharmacology 1996;50(2):266-76.
1996: H H Gu; J Ahn; Michael J Caplan; Randy D Blakely; Allan Levey; Gary Rudnick
Cell-specific sorting of biogenic amine transporters expressed in epithelial cells.
The Journal of biological chemistry 1996;271(30):18100-6.
1996: robert fremeau; M Velaz-Faircloth; Joshua Miller; V A Henzi; S M Cohen; J V Nadler; S Shafqat; Randy D Blakely; B Domin
A novel nonopioid action of enkephalins: competitive inhibition of the mammalian brain high affinity L-proline transporter.
Molecular pharmacology 1996;49(6):1033-41.
1996: John R Kelsoe; R A Remick; A D Sadovnick; H Kristbjarnarson; Pamela Flodman; M Anne Spence; M Morison; Z Mroczkowski-Parker; P Bergesch; Mark Hyman Rapaport; A L Mirow; Randy D Blakely; T Helgason; Janice A Egeland
Genetic linkage study of bipolar disorder and the serotonin transporter.
American journal of medical genetics 1996;67(2):215-7.
1996: Paul Wade; J Chen; B Jaffe; I S Kassem; Randy D Blakely; Michael D Gershon
Localization and function of a 5-HT transporter in crypt epithelia of the gastrointestinal tract.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1996;16(7):2352-64.
1996: L J DeFelice; Randy D Blakely
Pore models for transporters?
Biophysical journal 1996;70(2):579-80.
1996: S Risso; L J DeFelice; Randy D Blakely
Sodium-dependent GABA-induced currents in GAT1-transfected HeLa cells.
The Journal of physiology 1996;490 ( Pt 3)():691-702.
1996: Mario Saltarelli; Andrea L Bauman; K R Moore; C C Bradley; Randy D Blakely
Expression of the rat brain creatine transporter in situ and in transfected HeLa cells.
Developmental neuroscience 1996;18(5-6):524-34.
1995: A Galli; L J DeFelice; B J Duke; K R Moore; Randy D Blakely
Sodium-dependent norepinephrine-induced currents in norepinephrine-transporter-transfected HEK-293 cells blocked by cocaine and antidepressants.
The Journal of experimental biology 1995;198(Pt 10):2197-212.
1995: Y Qian; H E Melikian; D B Rye; Allan Levey; Randy D Blakely
Identification and characterization of antidepressant-sensitive serotonin transporter proteins using site-specific antibodies.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(2):1261-74.
1994: Eric L Barker; H L Kimmel; Randy D Blakely
Chimeric human and rat serotonin transporters reveal domains involved in recognition of transporter ligands.
Molecular pharmacology 1994;46(5):799-807.
1994: Randy D Blakely; L J De Felice; H Criss Hartzell
Molecular physiology of norepinephrine and serotonin transporters.
The Journal of experimental biology 1994;196():263-81.
1994: Christopher G Tate; Randy D Blakely
The effect of N-linked glycosylation on activity of the Na(+)- and Cl(-)-dependent serotonin transporter expressed using recombinant baculovirus in insect cells.
The Journal of biological chemistry 1994;269(42):26303-10.
1994: K R Moore; Randy D Blakely
Restriction site-independent formation of chimeras from homologous neurotransmitter-transporter cDNAs.
BioTechniques 1994;17(1):130-5, 137.
1994: Sammanda Ramamoorthy; Fred H Leibach; Virendra B Mahesh; H Han; T Yang-Feng; Randy D Blakely; Vadivel Ganapathy
Functional characterization and chromosomal localization of a cloned taurine transporter from human placenta.
The Biochemical journal 1994;300 ( Pt 3)():893-900.
1994: Mark C Austin; C C Bradley; J John Mann; Randy D Blakely
Expression of serotonin transporter messenger RNA in the human brain.
Journal of neurochemistry 1994;62(6):2362-7.
1994: L L Demchyshyn; Zdenek Pristupa; Kim S Sugamori; Eric L Barker; Randy D Blakely; William J Wolfgang; Michael Forte; Hyman B Niznik
Cloning, expression, and localization of a chloride-facilitated, cocaine-sensitive serotonin transporter from Drosophila melanogaster.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(11):5158-62.
1994: H E Melikian; J K McDonald; H Gu; G Rudnick; K R Moore; Randy D Blakely
Human norepinephrine transporter. Biosynthetic studies using a site-directed polyclonal antibody.
The Journal of biological chemistry 1994;269(16):12290-7.
1994: Bruce R Pitt; WEILI WENG; A R Steve; Randy D Blakely; I Reynolds; P Davies
Serotonin increases DNA synthesis in rat proximal and distal pulmonary vascular smooth muscle cells in culture.
The American journal of physiology 1994;266(2 Pt 1):L178-86.
1993: Sammanda Ramamoorthy; D R Cool; Virendra B Mahesh; Fred H Leibach; H E Melikian; Randy D Blakely; Vadivel Ganapathy
Regulation of the human serotonin transporter. Cholera toxin-induced stimulation of serotonin uptake in human placental choriocarcinoma cells is accompanied by increased serotonin transporter mRNA levels and serotonin transporter-specific ligand binding.
The Journal of biological chemistry 1993;268(29):21626-31.
1993: Sammanda Ramamoorthy; Andrea L Bauman; K R Moore; H Han; T Yang-Feng; Albert S Chang; Vadivel Ganapathy; Randy D Blakely
Antidepressant- and cocaine-sensitive human serotonin transporter: molecular cloning, expression, and chromosomal localization.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(6):2542-6.
1993: Sammanda Ramamoorthy; Puttur D Prasad; P Kulanthaivel; Fred H Leibach; Randy D Blakely; Vadivel Ganapathy
Expression of a cocaine-sensitive norepinephrine transporter in the human placental syncytiotrophoblast.
Biochemistry 1993;32(5):1346-53.
1993: Randy D Blakely; K R Moore; Y Qian
Tails of serotonin and norepinephrine transporters: deletions and chimeras retain function.
Society of General Physiologists series 1993;48():283-300.
1992: robert fremeau; Marc G Caron; Randy D Blakely
Molecular cloning and expression of a high affinity L-proline transporter expressed in putative glutamatergic pathways of rat brain.
Neuron 1992;8(5):915-26.
1992: Randy D Blakely; H E Berson
Molecular biology of serotonin receptors and transporters.
Clinical neuropharmacology 1992;15 Suppl 1 Pt A():351A-352A.
1992: Randy D Blakely
Molecular cloning and characterization of neurotransmitter transporters.
NIDA research monograph 1992;126():66-83.
1991: Randy D Blakely; H E Berson; robert fremeau; Marc G Caron; M M Peek; H K Prince; C C Bradley
Cloning and expression of a functional serotonin transporter from rat brain.
Nature 1991;354(6348):66-70.
1991: Randy D Blakely; J A Clark; Gary Rudnick; Susan Amara
Vaccinia-T7 RNA polymerase expression system: evaluation for the expression cloning of plasma membrane transporters.
Analytical biochemistry 1991;194(2):302-8.
1991: T Pacholczyk; Randy D Blakely; Susan Amara
Expression cloning of a cocaine- and antidepressant-sensitive human noradrenaline transporter.
Nature 1991;350(6316):350-4.
1991: Randy D Blakely; J A Clark; T Pacholczyk; Susan Amara
Distinct, developmentally regulated brain mRNAs direct the synthesis of neurotransmitter transporters.
Journal of neurochemistry 1991;56(3):860-71.
1990: T Pacholczyk; Randy D Blakely; Susan Amara
A device to rapidly core out tissue culture plates for autoradiographic visualization of cells transfected with cDNA libraries.
BioTechniques 1990;9(5):556, 558.
1988: Randy D Blakely; M B Robinson; Susan Amara
Expression of neurotransmitter transport from rat brain mRNA in Xenopus laevis oocytes.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(24):9846-50.
1988: Randy D Blakely; Michael B Robinson; Angela S Guarda; Joseph T Coyle
A re-examination of the interaction of N-acetyl-L-aspartyl-L-glutamate with a subpopulation of rat brain membrane L-[3H]glutamate binding sites.
European journal of pharmacology 1988;151(3):419-26.
1988: Angela S Guarda; Michael B Robinson; L Ory-Lavollée; Gianluigi Forloni; Randy D Blakely; Joseph T Coyle
Quantitation of N-acetyl-aspartyl-glutamate in microdissected rat brain nuclei and peripheral tissues: findings with a novel liquid phase radioimmunoassay.
Brain research 1988;427(3):223-31.
1988: Randy D Blakely; Michael B Robinson; R C Thompson; Joseph T Coyle
Hydrolysis of the brain dipeptide N-acetyl-L-aspartyl-L-glutamate: subcellular and regional distribution, ontogeny, and the effect of lesions on N-acetylated-alpha-linked acidic dipeptidase activity.
Journal of neurochemistry 1988;50(4):1200-9.
1988: Randy D Blakely; J T Coyle
The neurobiology of N-acetylaspartylglutamate.
International review of neurobiology 1988;30():39-100.
1987: Michael B Robinson; Randy D Blakely; R Couto; Joseph T Coyle
Hydrolysis of the brain dipeptide N-acetyl-L-aspartyl-L-glutamate. Identification and characterization of a novel N-acetylated alpha-linked acidic dipeptidase activity from rat brain.
The Journal of biological chemistry 1987;262(30):14498-506.
1987: Randy D Blakely; L Ory-Lavollée; Joseph T Coyle
Specific alterations in the levels of N-acetyl-aspartyl-glutamate in the nervous system of the dystrophic mouse.
Neuroscience letters 1987;79(1-2):223-8.
1987: L Ory-Lavollée; Randy D Blakely; Joseph T Coyle
Neurochemical and immunocytochemical studies on the distribution of N-acetyl-aspartylglutamate and N-acetyl-aspartate in rat spinal cord and some peripheral nervous tissues.
Journal of neurochemistry 1987;48(3):895-9.
1987: Randy D Blakely; L Ory-Lavollée; R Grzanna; K J Koller; Joseph T Coyle
Selective immunocytochemical staining of mitral cells in rat olfactory bulb with affinity purified antibodies against N-acetyl-aspartyl-glutamate.
Brain research 1987;402(2):373-8.
1987: Gianluigi Forloni; R Grzanna; Randy D Blakely; Joseph T Coyle
Co-localization of N-acetyl-aspartyl-glutamate in central cholinergic, noradrenergic, and serotonergic neurons.
Synapse (New York, N.Y.) 1987;1(5):455-60.
1986: M B Robinson; Randy D Blakely; J T Coyle
Quisqualate selectively inhibits a brain peptidase which cleaves N-acetyl-L-aspartyl-L-glutamate in vitro.
European journal of pharmacology 1986;130(3):345-7.
1986: Randy D Blakely; L Ory-Lavollée; R C Thompson; Joseph T Coyle
Synaptosomal transport of radiolabel from N-acetyl-aspartyl-[3H]glutamate suggests a mechanism of inactivation of an excitatory neuropeptide.
Journal of neurochemistry 1986;47(4):1013-9.
1986: Joseph T Coyle; Randy D Blakely; R Zaczek; K J Koller; M Abreu; L Ory-Lavollée; R Fisher; Jarlath ffrench-Mullen; D O Carpenter
Acidic peptides in brain: do they act at putative glutamatergic synapses?
Advances in experimental medicine and biology 1986;203():375-84.
1984: Randy D Blakely; S A Wages; J B Justice; James G. Herndon; D B Neill
Neuroleptics increase striatal catecholamine metabolites but not ascorbic acid in dialyzed perfusate.
Brain research 1984;308(1):1-8.
1983: Randy D Blakely; R C Duvarney
A microcomputer controlled system for monitoring multiple voltammetric electrodes in vivo.
Brain research bulletin 1983;10(3):315-20.
1981: W S Lindsay; James G. Herndon; Randy D Blakely; J B Justice; D B Neill
Voltammetric recording from neostriatum of behaving rhesus monkey.
Brain research 1981;220(2):391-6.
1980: James G. Herndon; W C Allen; Randy D Blakely
Increases in testosterone levels and in copulatory behavior of male rhesus monkeys following treatment with human chorionic gonadotrophin.
Hormones and behavior 1980;14(4):337-47.