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Eefje Schrauwen

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Eefje J A Schrauwen; Theo M Bestebroer; Ron A M Fouchier; Albert D M E Osterhaus; Guus F Rimmelzwaan; Sander Herfst
Reassortment between Avian H5N1 and human influenza viruses is mainly restricted to the matrix and neuraminidase gene segments.
Miranda de Graaf; Ron A M Fouchier; Sander Herfst; Theo M Luider; Albert D M E Osterhaus; Bob J Scholte; Eefje J A Schrauwen; Wilfred van Ijcken; Fatiha Zaaraoui-Boutahar; Jamil Aarbiou; Maarten Bijl; Peter C Burgers; Arno C Andeweg
Small hydrophobic protein of human metapneumovirus does not affect virus replication and host gene expression in vitro.
Colin A Russell; Eefje J A Schrauwen; David L Smith; Sander van Boheemen; André E X Brown; david burke; Judith M Fonville; Ron A M Fouchier; Sander Herfst; Sarah L James; Leah Katzelnick; Yoshihiro Kawaoka; Thijs Kuiken; Martin Linster; Eileen Maher; Ana Mosterín; Gabriele Neumann; Albert D M E Osterhaus; Derek J Smith
The potential for respiratory droplet-transmissible A/H5N1 influenza virus to evolve in a mammalian host.

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2013: Eefje J A Schrauwen; Theo M Bestebroer; Ron A M Fouchier; Albert D M E Osterhaus; Guus F Rimmelzwaan; Sander Herfst
Reassortment between Avian H5N1 and human influenza viruses is mainly restricted to the matrix and neuraminidase gene segments.
PloS one 2013;8(3):e59889.
2013: Miranda de Graaf; Ron A M Fouchier; Sander Herfst; Theo M Luider; Albert D M E Osterhaus; Bob J Scholte; Eefje J A Schrauwen; Wilfred van Ijcken; Fatiha Zaaraoui-Boutahar; Jamil Aarbiou; Maarten Bijl; Peter C Burgers; Arno C Andeweg
Small hydrophobic protein of human metapneumovirus does not affect virus replication and host gene expression in vitro.
PloS one 2013;8(3):e58572.
2012: Colin A Russell; Eefje J A Schrauwen; David L Smith; Sander van Boheemen; André E X Brown; david burke; Judith M Fonville; Ron A M Fouchier; Sander Herfst; Sarah L James; Leah Katzelnick; Yoshihiro Kawaoka; Thijs Kuiken; Martin Linster; Eileen Maher; Ana Mosterín; Gabriele Neumann; Albert D M E Osterhaus; Derek J Smith
The potential for respiratory droplet-transmissible A/H5N1 influenza virus to evolve in a mammalian host.
Science (New York, N.Y.) 2012;336(6088):1541-7.
2012: Sander Herfst; Martin Linster; Vincent J Munster; Albert D M E Osterhaus; Guus F Rimmelzwaan; Eefje J A Schrauwen; Derek J Smith; Erin M Sorrell; Theo M Bestebroer; david burke; Salin Chutinimitkul; Emmie de Wit; Ron A M Fouchier
Airborne transmission of influenza A/H5N1 virus between ferrets.
Science (New York, N.Y.) 2012;336(6088):1534-41.
2012: Eefje J A Schrauwen; Peter van Run; Theo M Bestebroer; Rogier Bodewes; Ron A M Fouchier; Sander Herfst; Joost H C M Kreijtz; Thijs Kuiken; Lonneke M Leijten; Martin Linster; Albert D M E Osterhaus; Guus F Rimmelzwaan; Debby van Riel
The multibasic cleavage site in H5N1 virus is critical for systemic spread along the olfactory and hematogenous routes in ferrets.
Journal of virology 2012;86(7):3975-84.
2011: E M Sorrell; Eefje J A Schrauwen; Miranda de Graaf; Sander Herfst; M Linster; R A M Fouchier
Predicting 'airborne' influenza viruses: (trans-) mission impossible?
Current opinion in virology 2011;1(6):635-42.
2011: Erhard van der Vries; Edwin Veldhuis Kroeze; Charles A B Boucher; Ron A M Fouchier; Thijs Kuiken; Lonneke M Leijten; Martin Linster; Albert D M E Osterhaus; Eefje J A Schrauwen; Martin Schutten; Koert J Stittelaar; Geert van Amerongen; Anne Van der Linden; Sander Herfst
Multidrug resistant 2009 A/H1N1 influenza clinical isolate with a neuraminidase I223R mutation retains its virulence and transmissibility in ferrets.
PLoS pathogens 2011;7(9):e1002276.
2011: Eefje J A Schrauwen; Theo M Bestebroer; Vincent J Munster; Elzo de Wit; Sander Herfst; Guus F Rimmelzwaan; Albert D M E Osterhaus; Ron A M Fouchier
Insertion of a multibasic cleavage site in the haemagglutinin of human influenza H3N2 virus does not increase pathogenicity in ferrets.
The Journal of general virology 2011;92(Pt 6):1410-5.
2011: Eefje J A Schrauwen; Sander Herfst; Salin Chutinimitkul; Theo M Bestebroer; Guus F Rimmelzwaan; Albert D M E Osterhaus; Thijs Kuiken; Ron A M Fouchier
Possible increased pathogenicity of pandemic (H1N1) 2009 influenza virus upon reassortment.
Emerging infectious diseases 2011;17(2):200-8.
2010: Salin Chutinimitkul; Sander Herfst; John Steel; Anice C Lowen; Jianqiang Ye; Debby van Riel; Eefje J A Schrauwen; Theo M Bestebroer; Björn Koel; david burke; Kyle H Sutherland-Cash; Chris S Whittleston; Colin A Russell; David J Wales; Derek J Smith; Marcel Jonges; Adam Meijer; Marion Koopmans; Guus F Rimmelzwaan; Thijs Kuiken; Albert D M E Osterhaus; Adolfo García-Sastre; Daniel R Perez; Ron A M Fouchier
Virulence-associated substitution D222G in the hemagglutinin of 2009 pandemic influenza A(H1N1) virus affects receptor binding.
Journal of virology 2010;84(22):11802-13.
2010: Vincent J Munster; Eefje J A Schrauwen; Emmie de Wit; Judith van den Brand; Theo M Bestebroer; Sander Herfst; Guus F Rimmelzwaan; Albert D M E Osterhaus; Ron A M Fouchier
Insertion of a multibasic cleavage motif into the hemagglutinin of a low-pathogenic avian influenza H6N1 virus induces a highly pathogenic phenotype.
Journal of virology 2010;84(16):7953-60.
2010: Sander Herfst; Salin Chutinimitkul; Jianqiang Ye; Emmie de Wit; Vincent J Munster; Eefje J A Schrauwen; Theo M Bestebroer; Marcel Jonges; Adam Meijer; Marion Koopmans; Guus F Rimmelzwaan; Albert D M E Osterhaus; Daniel R Perez; Ron A M Fouchier
Introduction of virulence markers in PB2 of pandemic swine-origin influenza virus does not result in enhanced virulence or transmission.
Journal of virology 2010;84(8):3752-8.
2009: Vincent J Munster; Emmie de Wit; Judith van den Brand; Sander Herfst; Eefje J A Schrauwen; Theo M Bestebroer; David van de Vijver; Charles A Boucher; Marion Koopmans; Guus F Rimmelzwaan; Thijs Kuiken; Albert D M E Osterhaus; Ron A M Fouchier
Pathogenesis and transmission of swine-origin 2009 A(H1N1) influenza virus in ferrets.
Science (New York, N.Y.) 2009;325(5939):481-3.
2009: Miranda de Graaf; Eefje J A Schrauwen; Sander Herfst; Geert van Amerongen; Albert D M E Osterhaus; Ron A M Fouchier
Fusion protein is the main determinant of metapneumovirus host tropism.
The Journal of general virology 2009;90(Pt 6):1408-16.
2008: Willem Huisman; Eefje J A Schrauwen; Edwin Tijhaar; Yasemin Süzer; Suzan D Pas; Geert van Amerongen; Gerd Sutter; Guus F Rimmelzwaan; Albert D M E Osterhaus
Evaluation of vaccination strategies against infection with feline immunodeficiency virus (FIV) based on recombinant viral vectors expressing FIV Rev and OrfA.
Veterinary immunology and immunopathology 2008;126(3-4):332-8.
2008: Willem Huisman; Eefje J A Schrauwen; Guus F Rimmelzwaan; Albert D M E Osterhaus
Intrahost evolution of envelope glycoprotein and OrfA sequences after experimental infection of cats with a molecular clone and a biological isolate of feline immunodeficiency virus.
Virus research 2008;137(1):24-32.
2008: Sander Herfst; Eefje J A Schrauwen; Miranda de Graaf; Geert van Amerongen; Bernadette van den Hoogen; Rik de Swart; Albert D M E Osterhaus; Ron A M Fouchier
Immunogenicity and efficacy of two candidate human metapneumovirus vaccines in cynomolgus macaques.
Vaccine 2008;26(33):4224-30.
2008: Sander Herfst; Miranda de Graaf; Eefje J A Schrauwen; Leo Sprong; Karim Hussain; Bernadette van den Hoogen; Albert D M E Osterhaus; Ron A M Fouchier
Generation of temperature-sensitive human metapneumovirus strains that provide protective immunity in hamsters.
The Journal of general virology 2008;89(Pt 7):1553-62.
2008: Willem Huisman; Eefje J A Schrauwen; Suzan D Pas; Geert van Amerongen; Guus F Rimmelzwaan; Albert D M E Osterhaus
Evaluation of ISCOM-adjuvanted subunit vaccines containing recombinant feline immunodeficiency virus Rev, OrfA and envelope protein in cats.
Vaccine 2008;26(21):2553-61.
2008: Miranda de Graaf; Sander Herfst; Eefje J A Schrauwen; Ying Choi; Bernadette van den Hoogen; Albert D M E Osterhaus; Ron A M Fouchier
Specificity and functional interaction of the polymerase complex proteins of human and avian metapneumoviruses.
The Journal of general virology 2008;89(Pt 4):975-83.
2007: Sander Herfst; Miranda de Graaf; Eefje J A Schrauwen; Nancy D Ulbrandt; Arnita Barber Barnes; Kannaki Senthil; Albert D M E Osterhaus; Ron A M Fouchier; Bernadette van den Hoogen
Immunization of Syrian golden hamsters with F subunit vaccine of human metapneumovirus induces protection against challenge with homologous or heterologous strains.
The Journal of general virology 2007;88(Pt 10):2702-9.
2007: Miranda de Graaf; Sander Herfst; Eefje J A Schrauwen; Bernadette van den Hoogen; Albert D M E Osterhaus; Ron A M Fouchier
An improved plaque reduction virus neutralization assay for human metapneumovirus.
Journal of virological methods 2007;143(2):169-74.
2004: Willem Huisman; Eefje J A Schrauwen; Suzan D Pas; Jos A Karlas; Guus F Rimmelzwaan; Albert D M E Osterhaus
Antibodies specific for hypervariable regions 3 to 5 of the feline immunodeficiency virus envelope glycoprotein are not solely responsible for vaccine-induced acceleration of challenge infection in cats.
The Journal of general virology 2004;85(Pt 7):1833-41.