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Nicolas Schröder

Research Profile

Chemicals & Drugs

Living Beings

Physiology

Innate Immunity

Anatomy

Disorders

Lyme Disease

Genes & Molecular Sequences

Single Nucleotide Polymorphism

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Publications

TOP 3
Nicolas W J Schröder; Almuth Brandis; Hans-Hilmar Goebel; Frank L Heppner; Axel-Michael Ladhoff; Werner Stenzel
Pipestem capillaries in necrotizing myopathy revisited.
Gunthard Stübs; Ulrich Zähringer; Volker Fingerle; Jörg Rademann; Ralf R Schumann; Nicolas W J Schröder
Acylated cholesteryl galactosides are ubiquitous glycolipid antigens among Borrelia burgdorferi sensu lato.
Timothy R Crother; Justin Karlin; Ellena Peterson; Nicolas W J Schröder; Kenichi Shimada; Anatoly Slepenkin; Randa Alsabeh; Shuang Chen; Moshe Arditi
Chlamydia pneumoniae infection induced allergic airway sensitization is controlled by regulatory T-cells and plasmacytoid dendritic cells.

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All Publications

2013: Nicolas W J Schröder; Almuth Brandis; Hans-Hilmar Goebel; Frank L Heppner; Axel-Michael Ladhoff; Werner Stenzel
Pipestem capillaries in necrotizing myopathy revisited.
Neuromuscular disorders : NMD 2013;23(1):66-74.
2011: Gunthard Stübs; Ulrich Zähringer; Volker Fingerle; Jörg Rademann; Ralf R Schumann; Nicolas W J Schröder
Acylated cholesteryl galactosides are ubiquitous glycolipid antigens among Borrelia burgdorferi sensu lato.
FEMS immunology and medical microbiology 2011;63(1):140-3.
2011: Timothy R Crother; Justin Karlin; Ellena Peterson; Nicolas W J Schröder; Kenichi Shimada; Anatoly Slepenkin; Randa Alsabeh; Shuang Chen; Moshe Arditi
Chlamydia pneumoniae infection induced allergic airway sensitization is controlled by regulatory T-cells and plasmacytoid dendritic cells.
PloS one 2011;6(6):e20784.
2010: Gunthard Stübs; Bernd Rupp; Ralf R Schumann; Nicolas W J Schröder; Jörg Rademann
Chemoenzymatic synthesis of a glycolipid library and elucidation of the antigenic epitope for construction of a vaccine against Lyme disease.
Chemistry (Weinheim an der Bergstrasse, Germany) 2010;16(11):3536-44.
2009: Gunthard Stübs; Volker Fingerle; Bettina Wilske; Ulf B Göbel; Ulrich Zähringer; Ralf R Schumann; Nicolas W J Schröder
Acylated cholesteryl galactosides are specific antigens of borrelia causing lyme disease and frequently induce antibodies in late stages of disease.
The Journal of biological chemistry 2009;284(20):13326-34.
2008: Yoshikazu Naiki; Rosalinda Sorrentino; Michelle H Wong; Kathrin S Michelsen; Kenichi Shimada; Shuang Chen; Atilla Yilmaz; Anatoly Slepenkin; Nicolas W J Schröder; Timothy R Crother; Yonca Bulut; Terence M Doherty; Michelle Bradley; Zory Shaposhnik; Ellena M Peterson; Peter Tontonoz; Prediman K Shah; Moshe Arditi
TLR/MyD88 and liver X receptor alpha signaling pathways reciprocally control Chlamydia pneumoniae-induced acceleration of atherosclerosis.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(10):7176-85.
2008: Nicolas W J Schröder; Timothy R Crother; Yoshikazu Naiki; Shuang Chen; Michelle H Wong; Atilla Yilmaz; Anatoly Slepenkin; Danica Schulte; Randa Alsabeh; Terence M Doherty; Ellena Peterson; Andre E Nel; Moshe Arditi
Innate immune responses during respiratory tract infection with a bacterial pathogen induce allergic airway sensitization.
The Journal of allergy and clinical immunology 2008;122(3):595-602.e5.
2008: Melanie Rose; Eva Dütting; Nicolas W J Schröder; Heinrich Sticht; Johann Helmut Brandstätter; Ralf Enz
PNUTS forms a trimeric protein complex with GABA(C) receptors and protein phosphatase 1.
Molecular and cellular neurosciences 2008;37(4):808-19.
2008: Nicolas W J Schröder; Jana Eckert; Gunthard Stübs; Ralf R Schumann
Immune responses induced by spirochetal outer membrane lipoproteins and glycolipids.
Immunobiology 2008;213(3-4):329-40.
2007: Atilla Yilmaz; Anne Rowley; Danica J Schulte; Terence M Doherty; Nicolas W J Schröder; Michael C Fishbein; Mitra B. Kalelkar; Iwona Cicha; Katja Schubert; Werner G Daniel; Christoph D. Garlichs; Moshe Arditi
Activated myeloid dendritic cells accumulate and co-localize with CD3+ T cells in coronary artery lesions in patients with Kawasaki disease.
Experimental and molecular pathology 2007;83(1):93-103.
2007: Nicolas W J Schröder; Marcus Maurer
The role of innate immunity in asthma: leads and lessons from mouse models.
Allergy 2007;62(6):579-90.
2007: Nicolas W J Schröder; Moshe Arditi
The role of innate immunity in the pathogenesis of asthma: evidence for the involvement of Toll-like receptor signaling.
Journal of endotoxin research 2007;13(5):305-12.
2006: Frank P Mockenhaupt; Jakob P Cramer; Lutz Hamann; M S Stegemann; Jana Eckert; Na-Ri Oh; Rowland N Otchwemah; Ekkehart Dietz; Stephan Ehrhardt; Nicolas W J Schröder; Ulrich Bienzle; Ralf R Schumann
Toll-like receptor (TLR) polymorphisms in African children: common TLR-4 variants predispose to severe malaria.
The Journal of communicable diseases 2006;38(3):230-45.
2006: Frank P Mockenhaupt; Jakob P Cramer; Lutz Hamann; Miriam S Stegemann; Jana Eckert; Na-Ri Oh; Rowland N Otchwemah; Ekkehart Dietz; Stephan Ehrhardt; Nicolas W J Schröder; Ulrich Bienzle; Ralf R Schumann
Toll-like receptor (TLR) polymorphisms in African children: Common TLR-4 variants predispose to severe malaria.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(1):177-82.
2005: Nicolas W J Schröder; Isabel Diterich; Antje Zinke; Jana Eckert; Christian Draing; Volker von Baehr; Dieter Hassler; Susanne Priem; Katrin Hahn; Kathrin S Michelsen; Thomas Hartung; Gerd R Burmester; Ulf B Göbel; Corinna Hermann; Ralf R Schumann
Heterozygous Arg753Gln polymorphism of human TLR-2 impairs immune activation by Borrelia burgdorferi and protects from late stage Lyme disease.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(4):2534-40.
2005: Yoshikazu Naiki; Kathrin S Michelsen; Nicolas W J Schröder; Randa Alsabeh; Anatoly Slepenkin; Wenxuan Zhang; Shuang Chen; Bo Wei; Yonca Bulut; Michelle H Wong; Ellena M Peterson; Moshe Arditi
MyD88 is pivotal for the early inflammatory response and subsequent bacterial clearance and survival in a mouse model of Chlamydia pneumoniae pneumonia.
The Journal of biological chemistry 2005;280(32):29242-9.
2005: Nicolas W J Schröder; D Meister; V Wolff; Claudia Christan; Dogan Kaner; Vesna Haban; Peter Purucker; Corinna Hermann; Annette Moter; Ulf B Göbel; Ralf R Schumann
Chronic periodontal disease is associated with single-nucleotide polymorphisms of the human TLR-4 gene.
Genes and immunity 2005;6(5):448-51.
2005: Daniela Bermpohl; Annett Halle; Dorette Freyer; Emilie Dagand; Johann S Braun; Ingo Bechmann; Nicolas W J Schröder; Joerg R Weber
Bacterial programmed cell death of cerebral endothelial cells involves dual death pathways.
The Journal of clinical investigation 2005;115(6):1607-15.
2005: Lutz Hamann; Abuzeid Gomma; Nicolas W J Schröder; Cordula Stamme; Christiane Glaeser; Susanne Schulz; Michael Gross; Stefan D Anker; Kim Fox; Ralf R Schumann
A frequent toll-like receptor (TLR)-2 polymorphism is a risk factor for coronary restenosis.
Journal of molecular medicine (Berlin, Germany) 2005;83(6):478-85.
2005: Nicolas W J Schröder; Ralf R Schumann
Single nucleotide polymorphisms of Toll-like receptors and susceptibility to infectious disease.
The Lancet infectious diseases 2005;5(3):156-64.
2005: Nicolas W J Schröder; Ralf R Schumann
Non-LPS targets and actions of LPS binding protein (LBP).
Journal of endotoxin research 2005;11(4):237-42.
2004: Nicolas W J Schröder; Holger Heine; Christian Alexander; Maria Manukyan; Jana Eckert; Lutz Hamann; Ulf B Göbel; Ralf R Schumann
Lipopolysaccharide binding protein binds to triacylated and diacylated lipopeptides and mediates innate immune responses.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(4):2683-91.
2004: Sonja Von Aulock; Nicolas W J Schröder; Stephanie Traub; Katja Gueinzius; Eva Lorenz; Thomas Hartung; Ralf R Schumann; Corinna Hermann
Heterozygous toll-like receptor 2 polymorphism does not affect lipoteichoic acid-induced chemokine and inflammatory responses.
Infection and immunity 2004;72(3):1828-31.
2003: Sonja Von Aulock; Nicolas W J Schröder; Katja Gueinzius; Stephanie Traub; Sebastian Hoffmann; Kathrin Graf; Stefanie Dimmeler; Thomas Hartung; Ralf R Schumann; Corinna Hermann
Heterozygous toll-like receptor 4 polymorphism does not influence lipopolysaccharide-induced cytokine release in human whole blood.
The Journal of infectious diseases 2003;188(6):938-43.
2003: Nicolas W J Schröder; Ursula Schombel; Holger Heine; Ulf B Göbel; Ulrich Zähringer; Ralf R Schumann
Acylated cholesteryl galactoside as a novel immunogenic motif in Borrelia burgdorferi sensu stricto.
The Journal of biological chemistry 2003;278(36):33645-53.
2003: Joerg R Weber; Dorette Freyer; Christian Alexander; Nicolas W J Schröder; Anja Reiss; Carsten Küster; Dagmar Pfeil; Elaine I Tuomanen; Ralf R Schumann
Recognition of pneumococcal peptidoglycan: an expanded, pivotal role for LPS binding protein.
Immunity 2003;19(2):269-79.
2003: Nicolas W J Schröder; Corinna Hermann; Lutz Hamann; Ulf B Göbel; Thomas Hartung; Ralf R Schumann
High frequency of polymorphism Arg753Gln of the Toll-like receptor-2 gene detected by a novel allele-specific PCR.
Journal of molecular medicine (Berlin, Germany) 2003;81(6):368-72.
2003: Nicolas W J Schröder; Siegfried Morath; Christian Alexander; Lutz Hamann; Thomas Hartung; Ulrich Zähringer; Ulf B Göbel; Joerg R Weber; Ralf R Schumann
Lipoteichoic acid (LTA) of Streptococcus pneumoniae and Staphylococcus aureus activates immune cells via Toll-like receptor (TLR)-2, lipopolysaccharide-binding protein (LBP), and CD14, whereas TLR-4 and MD-2 are not involved.
The Journal of biological chemistry 2003;278(18):15587-94.
2002: Corinna Hermann; Ingo Spreitzer; Nicolas W J Schröder; Siegfried Morath; Martin D Lehner; Werner Fischer; Christine Schütt; Ralf R Schumann; Thomas Hartung
Cytokine induction by purified lipoteichoic acids from various bacterial species--role of LBP, sCD14, CD14 and failure to induce IL-12 and subsequent IFN-gamma release.
European journal of immunology 2002;32(2):541-51.
2001: B Opitz; Nicolas W J Schröder; Ingo Spreitzer; Kathrin S Michelsen; Carsten J Kirschning; Werner Hallatschek; Ulrich Zähringer; Thomas Hartung; Ulf B Göbel; Ralf R Schumann
Toll-like receptor-2 mediates Treponema glycolipid and lipoteichoic acid-induced NF-kappaB translocation.
The Journal of biological chemistry 2001;276(25):22041-7.
2001: Nicolas W J Schröder; Dagmar Pfeil; B Opitz; Kathrin S Michelsen; J Amberger; Ulrich Zähringer; Ulf B Göbel; Ralf R Schumann
Activation of mitogen-activated protein kinases p42/44, p38, and stress-activated protein kinases in myelo-monocytic cells by Treponema lipoteichoic acid.
The Journal of biological chemistry 2001;276(13):9713-9.
2000: Nicolas W J Schröder; B Opitz; Norbert Lamping; Kathrin S Michelsen; Ulrich Zähringer; Ulf B Göbel; Ralf R Schumann
Involvement of lipopolysaccharide binding protein, CD14, and Toll-like receptors in the initiation of innate immune responses by Treponema glycolipids.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(5):2683-93.
1998: Norbert Lamping; R Dettmer; Nicolas W J Schröder; Dagmar Pfeil; Werner Hallatschek; R Burger; Ralf R Schumann
LPS-binding protein protects mice from septic shock caused by LPS or gram-negative bacteria.
The Journal of clinical investigation 1998;101(10):2065-71.