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Kornel Schuebel

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Reverse Transcriptase Polymerase Chain Reaction

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Jana Jeschke; Alexander Koch; Kornel E Schuebel; Wim van Criekinge; Leander Van Neste; Ilse Vlassenbroeck; Andreas Winterpacht; Stephen B Baylin; Marilia Freitas Calmon; Timothy A Chan; Leslie Cope; Valérie Deregowski; Mashaal Dhir; Edward Gabrielson; Sabine C Glöckner; James G Herman; Craig M Hooker; NITA AHUJA
Biomarkers for detection and prognosis of breast cancer identified by a functional hypermethylome screen.
Bani Mukhopadhyay; Resat Cinar; Shi Yin; Jie Liu; Joseph Tam; Grzegorz Godlewski; Judith Harvey-White; Isioma Mordi; Benjamin F Cravatt; Sophie Lotersztajn; Bin Gao; Qiaoping Yuan; Kornel E Schuebel; David Goldman; George Kunos
Hyperactivation of anandamide synthesis and regulation of cell-cycle progression via cannabinoid type 1 (CB1) receptors in the regenerating liver.
Joo-Mi Yi; Mashaal Dhir; Leander Van Neste; Stephanie R Downing; Jana Jeschke; Sabine C Glöckner; Marilia de Freitas Calmon; Craig M Hooker; Juan M Funes; Chris Boshoff; Kim M Smits; Manon van Engeland; Matty P Weijenberg; Christine A Iacobuzio-Donahue; James G Herman; Kornel E Schuebel; Stephen B Baylin; NITA AHUJA
Genomic and epigenomic integration identifies a prognostic signature in colon cancer.

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All Publications

2012: Jana Jeschke; Alexander Koch; Kornel E Schuebel; Wim van Criekinge; Leander Van Neste; Ilse Vlassenbroeck; Andreas Winterpacht; Stephen B Baylin; Marilia Freitas Calmon; Timothy A Chan; Leslie Cope; Valérie Deregowski; Mashaal Dhir; Edward Gabrielson; Sabine C Glöckner; James G Herman; Craig M Hooker; NITA AHUJA
Biomarkers for detection and prognosis of breast cancer identified by a functional hypermethylome screen.
Epigenetics : official journal of the DNA Methylation Society 2012;7(7):701-9.
2011: Bani Mukhopadhyay; Resat Cinar; Shi Yin; Jie Liu; Joseph Tam; Grzegorz Godlewski; Judith Harvey-White; Isioma Mordi; Benjamin F Cravatt; Sophie Lotersztajn; Bin Gao; Qiaoping Yuan; Kornel E Schuebel; David Goldman; George Kunos
Hyperactivation of anandamide synthesis and regulation of cell-cycle progression via cannabinoid type 1 (CB1) receptors in the regenerating liver.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(15):6323-8.
2011: Joo-Mi Yi; Mashaal Dhir; Leander Van Neste; Stephanie R Downing; Jana Jeschke; Sabine C Glöckner; Marilia de Freitas Calmon; Craig M Hooker; Juan M Funes; Chris Boshoff; Kim M Smits; Manon van Engeland; Matty P Weijenberg; Christine A Iacobuzio-Donahue; James G Herman; Kornel E Schuebel; Stephen B Baylin; NITA AHUJA
Genomic and epigenomic integration identifies a prognostic signature in colon cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(6):1535-45.
2010: Hariharan P Easwaran; Leander Van Neste; Leslie Cope; Subhojit Sen; Helai P Mohammad; Gayle J Pageau; Jeanne B Lawrence; James G Herman; Kornel E Schuebel; Stephen B Baylin
Aberrant silencing of cancer-related genes by CpG hypermethylation occurs independently of their spatial organization in the nucleus.
Cancer research 2010;70(20):8015-24.
2010: Joyce E Ohm; Prashant Mali; Leander Van Neste; berman david; Liang Liang; Kurinji Pandiyan; Kimberly J Briggs; Wei Zhang; Pedram Argani; Brian Simons; Wayne Yu; William Matsui; Wim van Criekinge; Feyruz V Rassool; ELIAS ZAMBIDIS; Kornel E Schuebel; Leslie Cope; Jonathan Yen; Helai P Mohammad; Linzhao Cheng; Stephen B Baylin
Cancer-related epigenome changes associated with reprogramming to induced pluripotent stem cells.
Cancer research 2010;70(19):7662-73.
2010: Iris J H van Vlodrop; Marcella M L Baldewijns; Kim M Smits; Leo J Schouten; Leander van Neste; Wim van Criekinge; Hein van Poppel; Evelyne Lerut; Kornel E Schuebel; NITA AHUJA; James G Herman; Adriaan P de Bruïne; Manon van Engeland
Prognostic significance of Gremlin1 (GREM1) promoter CpG island hypermethylation in clear cell renal cell carcinoma.
The American journal of pathology 2010;176(2):575-84.
2009: Mathewos Tessema; Yang Y Yu; Christine A Stidley; Emi O Machida; Kornel E Schuebel; Stephen B Baylin; Steven A Belinsky
Concomitant promoter methylation of multiple genes in lung adenocarcinomas from current, former and never smokers.
Carcinogenesis 2009;30(7):1132-8.
2009: Sabine C Glöckner; Mashaal Dhir; Joo-Mi Yi; Kelly E McGarvey; Leander Van Neste; joost louwagie; Timothy Chan; Wolfram Kleeberger; Adriaan P de Bruïne; Kim M Smits; Carolina A J Khalid-de Bakker; Daisy M A E Jonkers; Reinhold W Stockbrügger; Gerrit A Meijer; Frank A Oort; Christine A Iacobuzio-Donahue; Katja Bierau; James G Herman; Stephen B Baylin; Manon Van Engeland; Kornel E Schuebel; NITA AHUJA
Methylation of TFPI2 in stool DNA: a potential novel biomarker for the detection of colorectal cancer.
Cancer research 2009;69(11):4691-9.
2008: Joo-Mi Yi; Hsing-Chen Tsai; Sabine C Glöckner; Steven Lin; Joyce E Ohm; Hari Easwaran; C David James; Joseph F Costello; Gregory J Riggins; Charles G Eberhart; John Laterra; Angelo L Vescovi; NITA AHUJA; James G Herman; Kornel E Schuebel; Stephen B Baylin
Abnormal DNA methylation of CD133 in colorectal and glioblastoma tumors.
Cancer research 2008;68(19):8094-103.
2008: Mashaal Dhir; Elizabeth Montgomery; Sabine C Glöckner; Kornel E Schuebel; Craig M Hooker; James G Herman; Stephen B Baylin; Susan L Gearhart; NITA AHUJA
Epigenetic regulation of WNT signaling pathway genes in inflammatory bowel disease (IBD) associated neoplasia.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2008;12(10):1745-53.
2008: Kelly M McGarvey; Leander Van Neste; Leslie Cope; Joyce E Ohm; James G Herman; Wim van Criekinge; Kornel E Schuebel; Stephen B Baylin
Defining a chromatin pattern that characterizes DNA-hypermethylated genes in colon cancer cells.
Cancer research 2008;68(14):5753-9.
2008: Timothy Chan; Sabine Glockner; Joo-Mi Yi; Wei Chen; Leander Van Neste; Leslie Cope; James G Herman; Victor E Velculescu; Kornel E Schuebel; NITA AHUJA; Stephen B Baylin
Convergence of mutation and epigenetic alterations identifies common genes in cancer that predict for poor prognosis.
PLoS medicine 2008;5(5):e114.
2008: Wei Zhang; Sabine C Glöckner; Mingzhou Guo; Emi Ota Machida; David H Wang; Hariharan Easwaran; Leander Van Neste; James G Herman; Kornel E Schuebel; DAVID WATKINS; NITA AHUJA; Stephen B Baylin
Epigenetic inactivation of the canonical Wnt antagonist SRY-box containing gene 17 in colorectal cancer.
Cancer research 2008;68(8):2764-72.
2008: Angela H Ting; Hiromu Suzuki; Leslie Cope; Kornel E Schuebel; Byron H Lee; Minoru Toyota; Kohzoh Imai; Yasuhisa Shinomura; Takashi Tokino; Stephen B Baylin
A requirement for DICER to maintain full promoter CpG island hypermethylation in human cancer cells.
Cancer research 2008;68(8):2570-5.
2007: Kornel E Schuebel; Wei Chen; Leslie Cope; Sabine C Glöckner; Hiromu Suzuki; Joo-Mi Yi; Timothy Chan; Leander Van Neste; Wim van Criekinge; Sandra van den Bosch; Manon van Engeland; Angela H Ting; Kam-Wing Jair; Wayne Yu; Minoru Toyota; Kohzoh Imai; NITA AHUJA; James G Herman; Stephen B Baylin
Comparing the DNA hypermethylome with gene mutations in human colorectal cancer.
PLoS genetics 2007;3(9):1709-23.
2007: Stephen B Baylin; Kornel E Schuebel
Genomic biology: the epigenomic era opens.
Nature 2007;448(7153):548-9.
2007: Joyce E Ohm; Kelly M McGarvey; Xiaobing Yu; Linzhao Cheng; Kornel E Schuebel; Leslie Cope; Helai P Mohammad; Wei Chen; Vincent C Daniel; Wayne Yu; berman david; Thomas Jenuwein; Kevin Pruitt; Saul J Sharkis; DAVID WATKINS; James G Herman; Stephen B Baylin
A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing.
Nature genetics 2007;39(2):237-42.
2007: Joo-Mi Yi; Kornel E Schuebel; Heui-Soo Kim
Molecular genetic analyses of human endogenous retroviral elements belonging to the HERV-P family in primates, human tissues, and cancer cells.
Genomics 2007;89(1):1-9.
2006: Kornel E Schuebel; Wei Chen; Stephen B Baylin
CIMPle origin for promoter hypermethylation in colorectal cancer?
Nature genetics 2006;38(7):738-40.
2006: Angela H Ting; Kam-Wing Jair; Kornel E Schuebel; Stephen B Baylin
Differential requirement for DNA methyltransferase 1 in maintaining human cancer cell gene promoter hypermethylation.
Cancer research 2006;66(2):729-35.
2006: Kam-Wing Jair; Kurtis E Bachman; Hiromu Suzuki; Angela H Ting; Ina Rhee; Ray-Whay Chiu Yen; Stephen B Baylin; Kornel E Schuebel
De novo CpG island methylation in human cancer cells.
Cancer research 2006;66(2):682-92.
2005: Kornel E Schuebel; Stephen B Baylin
In living color: DNA methyltransferase caught in the act.
Nature methods 2005;2(10):736-8.
2005: Angela H Ting; Kornel E Schuebel; James G Herman; Stephen B Baylin
Short double-stranded RNA induces transcriptional gene silencing in human cancer cells in the absence of DNA methylation.
Nature genetics 2005;37(8):906-10.
2005: Eric K Nakakura; Virote Sriuranpong; Muthusamy Kunnimalaiyaan; Edward C Hsiao; Kornel E Schuebel; Michael W Borges; Ning Jin; Brendan J Collins; Barry D Nelkin; Herbert Chen; Douglas W Ball
Regulation of neuroendocrine differentiation in gastrointestinal carcinoid tumor cells by notch signaling.
The Journal of clinical endocrinology and metabolism 2005;90(7):4350-6.
2004: Angela H Ting; Kam-Wing Jair; Hiromu Suzuki; Ray-Whay Chiu Yen; Stephen B Baylin; Kornel E Schuebel
Mammalian DNA methyltransferase 1: inspiration for new directions.
Cell cycle (Georgetown, Tex.) 2004;3(8):1024-6.
2004: Angela H Ting; Kam-Wing Jair; Hiromu Suzuki; Ray-Whay Chiu Yen; Stephen B Baylin; Kornel E Schuebel
CpG island hypermethylation is maintained in human colorectal cancer cells after RNAi-mediated depletion of DNMT1.
Nature genetics 2004;36(6):582-4.
2004: Hiromu Suzuki; DAVID WATKINS; Kam-Wing Jair; Kornel E Schuebel; Sanford D Markowitz; Wei Dong Chen; Theresa P Pretlow; Bin Yang; Yoshimitsu Akiyama; Manon van Engeland; Minoru Toyota; Takashi Tokino; Yuji Hinoda; Kohzoh Imai; James G Herman; Stephen B Baylin
Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer.
Nature genetics 2004;36(4):417-22.
2003: Minoru Toyota; Yasushi Sasaki; Ayumi Satoh; Kazuhiro Ogi; Takefumi Kikuchi; Hiromu Suzuki; Hiroaki Mita; Nobuyuki Tanaka; Fumio Itoh; Jean-Pierre J Issa; Kam-Wing Jair; Kornel E Schuebel; Kohzoh Imai; Takashi Tokino
Epigenetic inactivation of CHFR in human tumors.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(13):7818-23.
2002: Ina Rhee; Kurtis E Bachman; Ben Ho Park; Kam-Wing Jair; Ray-Whay Chiu Yen; Kornel E Schuebel; Hengmi Cui; Andrew P Feinberg; Christoph Lengauer; Kenneth W Kinzler; Stephen B Baylin; Bert Vogelstein
DNMT1 and DNMT3b cooperate to silence genes in human cancer cells.
Nature 2002;416(6880):552-6.
2001: Stephen B Baylin; Manel Esteller; Michael R Rountree; Kurtis E Bachman; Kornel E Schuebel; James G Herman
Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer.
Human molecular genetics 2001;10(7):687-92.
2001: Eric K Nakakura; DAVID WATKINS; Kornel E Schuebel; Virote Sriuranpong; Michael W Borges; Barry D Nelkin; Douglas W Ball
Mammalian Scratch: a neural-specific Snail family transcriptional repressor.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(7):4010-5.
2000: Ina Rhee; Kam-Wing Jair; Ray-Whay Chiu Yen; Christoph Lengauer; James G Herman; Kenneth W Kinzler; Bert Vogelstein; Stephen B Baylin; Kornel E Schuebel
CpG methylation is maintained in human cancer cells lacking DNMT1.
Nature 2000;404(6781):1003-7.
1999: Alessandro Rotondo; Kornel E Schuebel; A Bergen; Richard Aragon; Matti Virkkunen; Markku Linnoila; David Goldman; D Nielsen
Identification of four variants in the tryptophan hydroxylase promoter and association to behavior.
Molecular psychiatry 1999;4(4):360-8.
1998: Kornel E Schuebel; Nieves Movilla; J L Rosa; Xose Bustelo
Phosphorylation-dependent and constitutive activation of Rho proteins by wild-type and oncogenic Vav-2.
The EMBO journal 1998;17(22):6608-21.
1998: WD Hardt; L M Chen; Kornel E Schuebel; Xose Bustelo; JE Galán
S. typhimurium encodes an activator of Rho GTPases that induces membrane ruffling and nuclear responses in host cells.
Cell 1998;93(5):815-26.
1997: Piero Crespo; Kornel E Schuebel; A A Ostrom; J Silvio Gutkind; Xose Bustelo
Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product.
Nature 1997;385(6612):169-72.
1996: WN Henley; Kornel E Schuebel; DA Nielsen
Limitations imposed by heteroduplex formation on quantitative RT-PCR.
Biochemical and biophysical research communications 1996;226(1):113-7.
1996: Kornel E Schuebel; Xose Bustelo; DA Nielsen; Byoung J Song; Mariano Barbacid; David Goldman; I J Lee
Isolation and characterization of murine vav2, a member of the vav family of proto-oncogenes.
Oncogene 1996;13(2):363-71.
1986: T Shimizu; J Noguchi; Kornel E Schuebel; T Miyake; M J Murphy
Neuraminidase and hematopoietic factors from human urine.
Experimental cell biology 1986;54(4):225-33.
1985: Y Iizuka; K Noguchi; Kornel E Schuebel; T Miyake; M J Murphy
A quantitative assay for mouse granulocyte (CFU-g) and macrophage (CFU-m) precursors using plasma clots.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1985;33(7):617-23.