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Beatrice Schuler-Thurner

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Caroline Voskens; Eckhart Kaempgen; Gerold Schuler; Beatrice Schuler-Thurner; Alexander Cavallaro; Olga Dippel; Michael Erdmann; Lucie Heinzerling
Anti-cytotoxic T-cell lymphocyte antigen-4-induced regression of spinal cord metastases in association with renal failure, atypical pneumonia, vision loss, and hearing loss.
Svenja Debey-Pascher; Andrea Hofmann; Fatima Kreusch; Gerold Schuler; Beatrice Schuler-Thurner; Joachim L Schultze; Andrea Staratschek-Jox
RNA-stabilized whole blood samples but not peripheral blood mononuclear cells can be stored for prolonged time periods prior to transcriptome analysis.
I Jolanda M De Vries; Chiara Castelli; Caroline Huygens; Joannes F M Jacobs; Julie Stockis; Beatrice Schuler-Thurner; Gosse J Adema; Cornelis J A Punt; Licia Rivoltini; Gerold Schuler; Pierre G Coulie; Sophie Lucas
Frequency of circulating Tregs with demethylated FOXP3 intron 1 in melanoma patients receiving tumor vaccines and potentially Treg-depleting agents.

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All Publications

2012: Caroline Voskens; Eckhart Kaempgen; Gerold Schuler; Beatrice Schuler-Thurner; Alexander Cavallaro; Olga Dippel; Michael Erdmann; Lucie Heinzerling
Anti-cytotoxic T-cell lymphocyte antigen-4-induced regression of spinal cord metastases in association with renal failure, atypical pneumonia, vision loss, and hearing loss.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2012;30(33):e356-7.
2011: Svenja Debey-Pascher; Andrea Hofmann; Fatima Kreusch; Gerold Schuler; Beatrice Schuler-Thurner; Joachim L Schultze; Andrea Staratschek-Jox
RNA-stabilized whole blood samples but not peripheral blood mononuclear cells can be stored for prolonged time periods prior to transcriptome analysis.
The Journal of molecular diagnostics : JMD 2011;13(4):452-60.
2011: I Jolanda M De Vries; Chiara Castelli; Caroline Huygens; Joannes F M Jacobs; Julie Stockis; Beatrice Schuler-Thurner; Gosse J Adema; Cornelis J A Punt; Licia Rivoltini; Gerold Schuler; Pierre G Coulie; Sophie Lucas
Frequency of circulating Tregs with demethylated FOXP3 intron 1 in melanoma patients receiving tumor vaccines and potentially Treg-depleting agents.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(4):841-8.
2010: Katrin Birkholz; Michael Schwenkert; Christian Kellner; Stefanie Gross; Georg H Fey; Beatrice Schuler-Thurner; Gerold Schuler; Niels Schaft; Jan Dörrie
Targeting of DEC-205 on human dendritic cells results in efficient MHC class II-restricted antigen presentation.
Blood 2010;116(13):2277-85.
2010: Michael Erdmann; Beatrice Schuler-Thurner
Towards a standardized protocol for the generation of monocyte-derived dendritic cell vaccines.
Methods in molecular biology (Clifton, N.J.) 2010;595():149-63.
2008: M Erdmann; Beatrice Schuler-Thurner
Dendritic cell vaccines in metastasized malignant melanoma.
Giornale italiano di dermatologia e venereologia : organo ufficiale, Società italiana di dermatologia e sifilografia 2008;143(4):235-50.
2008: Thierry Connerotte; Aline Van Pel; Danièle Godelaine; Eric Tartour; Beatrice Schuler-Thurner; Sophie Lucas; Kris Thielemans; Gerold Schuler; Pierre G Coulie
Functions of Anti-MAGE T-cells induced in melanoma patients under different vaccination modalities.
Cancer research 2008;68(10):3931-40.
2008: Michael Schwenkert; Katrin Birkholz; Michael Schwemmlein; Christian Kellner; Markus Kügler; Matthias Peipp; Dirk M Nettelbeck; Beatrice Schuler-Thurner; Niels Schaft; Jan Dörrie; Soldano Ferrone; Eckhart Kämpgen; Georg H Fey
A single chain immunotoxin, targeting the melanoma-associated chondroitin sulfate proteoglycan, is a potent inducer of apoptosis in cultured human melanoma cells.
Melanoma research 2008;18(2):73-84.
2007: Michael Erdmann; Jan Dörrie; Niels Schaft; Erwin Strasser; Martin Hendelmeier; Eckhart Kämpgen; Gerold Schuler; Beatrice Schuler-Thurner
Effective clinical-scale production of dendritic cell vaccines by monocyte elutriation directly in medium, subsequent culture in bags and final antigen loading using peptides or RNA transfection.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2007;30(6):663-74.
2007: Cornelia Erfurt; Zhaojun Sun; Ina Haendle; Beatrice Schuler-Thurner; Carlo Heirman; Kris Thielemans; Pierre van der Bruggen; Gerold Schuler; Erwin S Schultz
Tumor-reactive CD4+ T cell responses to the melanoma-associated chondroitin sulphate proteoglycan in melanoma patients and healthy individuals in the absence of autoimmunity.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(12):7703-9.
2007: Henrike Körner; Alexey Epanchintsev; Carola Berking; Beatrice Schuler-Thurner; Michael R Speicher; Antje Menssen; Heiko Hermeking
Digital karyotyping reveals frequent inactivation of the dystrophin/DMD gene in malignant melanoma.
Cell cycle (Georgetown, Tex.) 2007;6(2):189-98.
2006: Dirk Schadendorf; Selma Ugurel; Beatrice Schuler-Thurner; F O Nestle; A Enk; Eva-B Bröcker; S Grabbe; Werner Rittgen; Lutz Edler; Antje Sucker; Christine Zimpfer-Rechner; T Berger; Jivko Kamarashev; G Burg; H Jonuleit; A Tüttenberg; Jürgen C Becker; Petra Keikavoussi; E Kämpgen; Gerold Schuler
Dacarbazine (DTIC) versus vaccination with autologous peptide-pulsed dendritic cells (DC) in first-line treatment of patients with metastatic melanoma: a randomized phase III trial of the DC study group of the DeCOG.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2006;17(4):563-70.
2006: Wolfgang Römer; Anton Nömayr; Holger Greess; E Fiedler; Günther Platsch; Beatrice Schuler-Thurner; Annette Pfahlberg; Torsten Hothorn; Gerold Schuler; Joachim Hornegger; Werner Bautz; Torsten Kuwert
Retrospective interactive rigid fusion of (18)F-FDG-PET and CT. Additional diagnostic information in melanoma patients.
Nuklearmedizin. Nuclear medicine 2006;45(2):88-95.
2005: Beatrice Schuler-Thurner; Gerold Schuler
[Vaccination therapy of melanoma].
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2005;3(8):630-45.
2005: Christian Maczek; Thomas G Berger; Beatrice Schuler-Thurner; Erwin S Schultz; Anett Hamann; P Rod Dunbar; Vincenzo Cerundolo; Alexander Steinkasserer; Gerold Schuler
Differences in phenotype and function between spontaneously occurring melan-A-, tyrosinase- and influenza matrix peptide-specific CTL in HLA-A*0201 melanoma patients.
International journal of cancer. Journal international du cancer 2005;115(3):450-5.
2005: Ralf G Meyer; Cedrik Michael Britten; Ulrike Siepmann; Barbara Petzold; Tolga A Sagban; Hans-Anton Lehr; Bernd Weigle; Marc Schmitz; Luis Mateo; Burkhard Schmidt; Helga Bernhard; Thilo Jakob; Rüdiger Hein; Gerold Schuler; Beatrice Schuler-Thurner; Stephan N Wagner; Ingo Drexler; Gerd Sutter; Nathaly Arndtz; Paul Chaplin; Jost Metz; Alexander Enk; Christoph Huber; Thomas Wölfel
A phase I vaccination study with tyrosinase in patients with stage II melanoma using recombinant modified vaccinia virus Ankara (MVA-hTyr).
Cancer immunology, immunotherapy : CII 2005;54(5):453-67.
2005: Yi Zhang; Nicolina Renkvist; Zhaojun Sun; Beatrice Schuler-Thurner; Nicolas Glaichenhaus; Gerold Schuler; Thierry Boon; Pierre van der Bruggen; Didier Colau
A polyclonal anti-vaccine CD4 T cell response detected with HLA-DP4 multimers in a melanoma patient vaccinated with MAGE-3.DP4-peptide-pulsed dendritic cells.
European journal of immunology 2005;35(4):1066-75.
2005: Thomas G Berger; Erwin Strasser; Richard Smith; Curt Carste; Beatrice Schuler-Thurner; Eckhart Kaempgen; Gerold Schuler
Efficient elutriation of monocytes within a closed system (Elutra) for clinical-scale generation of dendritic cells.
Journal of immunological methods 2005;298(1-2):61-72.
2005: Claudia Roeder; Beatrice Schuler-Thurner; Susanne Berchtold; Gisela Vieth; Peter von den Driesch; Gerold Schuler; Matthias Lüftl
MAGE-A3 is a frequent tumor antigen of metastasized melanoma.
Archives of dermatological research 2005;296(7):314-9.
2004: Thomas G Berger; Ina Haendle; David Schrama; Matthias Lüftl; Nicolas Bauer; Lars Østergaard Pedersen; Beatrice Schuler-Thurner; Werner Hohenberger; Per thor Straten Pt; Gerold Schuler; Jürgen C Becker
Circulation and homing of melanoma-reactive T cells to both cutaneous and visceral metastases after vaccination with monocyte-derived dendritic cells.
International journal of cancer. Journal international du cancer 2004;111(2):229-37.
2004: Erwin S Schultz; Beatrice Schuler-Thurner; Vincent Stroobant; Lars Jenne; Thomas G Berger; Kris Thielemanns; Pierre van der Bruggen; Gerold Schuler
Functional analysis of tumor-specific Th cell responses detected in melanoma patients after dendritic cell-based immunotherapy.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(2):1304-10.
2003: Danièle Godelaine; Javier Carrasco; Sophie Lucas; VAIOS KARANIKAS; Beatrice Schuler-Thurner; Pierre G Coulie; Gerold Schuler; Thierry Boon; Aline Van Pel
Polyclonal CTL responses observed in melanoma patients vaccinated with dendritic cells pulsed with a MAGE-3.A1 peptide.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(9):4893-7.
2003: Erwin Strasser; Thomas G Berger; Volker Weisbach; Robert Zimmermann; Jürgen Ringwald; Beatrice Schuler-Thurner; Jürgen Zingsem; Reinhold Eckstein
Comparison of two apheresis systems for the collection of CD14+ cells intended to be used in dendritic cell culture.
Transfusion 2003;43(9):1309-16.
2003: Gerold Schuler; Beatrice Schuler-Thurner; Ralph M Steinman
The use of dendritic cells in cancer immunotherapy.
Current opinion in immunology 2003;15(2):138-47.
2002: Mary A Marovich; John R Mascola; Michael A Eller; Mark K Louder; Pierre A Caudrelier; Raphaelle El Habib; Silvia Ratto-Kim; Josephine H Cox; Jeffrey R Currier; Bruce L Levine; Carl H June; Wendy B Bernstein; Merlin L Robb; Beatrice Schuler-Thurner; Ralph M Steinman; Deborah L Birx; Sarah Schlesinger-Frankel
Preparation of clinical-grade recombinant canarypox-human immunodeficiency virus vaccine-loaded human dendritic cells.
The Journal of infectious diseases 2002;186(9):1242-52.
2002: Thomas G Berger; Bernadette Feuerstein; Erwin Strasser; Ute Hirsch; Doris Schreiner; Gerold Schuler; Beatrice Schuler-Thurner
Large-scale generation of mature monocyte-derived dendritic cells for clinical application in cell factories.
Journal of immunological methods 2002;268(2):131-40.
2002: Beatrice Schuler-Thurner; Erwin S Schultz; Thomas G Berger; Georg Weinlich; Susanne Ebner; Petra Woerl; Armin Bender; Bernadette Feuerstein; Peter O Fritsch; Nikolaus Romani; Gerold Schuler
Rapid induction of tumor-specific type 1 T helper cells in metastatic melanoma patients by vaccination with mature, cryopreserved, peptide-loaded monocyte-derived dendritic cells.
The Journal of experimental medicine 2002;195(10):1279-88.
2001: Mads Hald Andersen; Petra Keikavoussi; Eva-B Bröcker; Beatrice Schuler-Thurner; M Jonassen; Ib Søndergaard; Per thor Straten; Jürgen C Becker; Eckhart Kämpgen
Induction of systemic CTL responses in melanoma patients by dendritic cell vaccination: cessation of CTL responses is associated with disease progression.
International journal of cancer. Journal international du cancer 2001;94(6):820-4.
2001: Anke Glaser; Beatrice Schuler-Thurner; Bernadette Feuerstein; Jürgen Zingsem; Robert Zimmermann; Volker Weisbach; Reinhold Eckstein
Collection of MNCs with two cell separators for adoptive immunotherapy in patients with stage IV melanoma.
Transfusion 2001;41(1):117-22.
2000: Bernadette Feuerstein; Thomas G Berger; Christian Maczek; C Röder; Doris Schreiner; U Hirsch; Ina Haendle; W Leisgang; Anke Glaser; Oliver Kuss; Thomas L Diepgen; Gerold Schuler; Beatrice Schuler-Thurner
A method for the production of cryopreserved aliquots of antigen-preloaded, mature dendritic cells ready for clinical use.
Journal of immunological methods 2000;245(1-2):15-29.
2000: Beatrice Schuler-Thurner; Detlef Dieckmann; Petra Keikavoussi; Armin Bender; Christian Maczek; H Jonuleit; C Röder; Ina Haendle; W Leisgang; R Dunbar; Vincenzo Cerundolo; Peter von den Driesch; J Knop; Eva-B Bröcker; A Enk; Eckhart Kämpgen; Gerold Schuler
Mage-3 and influenza-matrix peptide-specific cytotoxic T cells are inducible in terminal stage HLA-A2.1+ melanoma patients by mature monocyte-derived dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(6):3492-6.