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Günter Schultz

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Rainer Strotmann; Günter Schultz; Tim D Plant
Ca2+-dependent potentiation of the nonselective cation channel TRPV4 is mediated by a C-terminal calmodulin binding site.
Christian Grimm; Robert Kraft; Sophie Sauerbruch; Günter Schultz; Christian Harteneck
Molecular and functional characterization of the melastatin-related cation channel TRPM3.
Hemasse Amiri; Günter Schultz; Michael Schaefer
FRET-based analysis of TRPC subunit stoichiometry.

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All Publications

2003: Rainer Strotmann; Günter Schultz; Tim D Plant
Ca2+-dependent potentiation of the nonselective cation channel TRPV4 is mediated by a C-terminal calmodulin binding site.
The Journal of biological chemistry 2003;278(29):26541-9.
2003: Christian Grimm; Robert Kraft; Sophie Sauerbruch; Günter Schultz; Christian Harteneck
Molecular and functional characterization of the melastatin-related cation channel TRPM3.
The Journal of biological chemistry 2003;278(24):21493-501.
2003: Hemasse Amiri; Günter Schultz; Michael Schaefer
FRET-based analysis of TRPC subunit stoichiometry.
Cell calcium 2003;33(5-6):463-70.
2003: Silke Jung; Anja Mühle; Michael Schaefer; Rainer Strotmann; Günter Schultz; Tim D Plant
Lanthanides potentiate TRPC5 currents by an action at extracellular sites close to the pore mouth.
The Journal of biological chemistry 2003;278(6):3562-71.
2002: Katrin Sangkuhl; Angela Schulz; Günter Schultz; Torsten Schöneberg
Structural requirements for mutational lutropin/choriogonadotropin receptor activation.
The Journal of biological chemistry 2002;277(49):47748-55.
2002: Angela Schulz; Katrin Sangkuhl; Thomas Lennert; Marianne Wigger; David Anthony Price; Anja Nuuja; Annette Grüters; Günter Schultz; Torsten Schöneberg
Aminoglycoside pretreatment partially restores the function of truncated V(2) vasopressin receptors found in patients with nephrogenic diabetes insipidus.
The Journal of clinical endocrinology and metabolism 2002;87(11):5247-57.
2002: Johannes C Lenz; Hans Peter Reusch; Nadine Albrecht; Günter Schultz; Michael Schaefer
Ca2+-controlled competitive diacylglycerol binding of protein kinase C isoenzymes in living cells.
The Journal of cell biology 2002;159(2):291-302.
2002: Christian Harteneck; Sabina Naranjo Kuchta; Armin Huber; Reinhard Paulsen; Günter Schultz
The PDZ scaffold protein INAD abolishes apparent store-dependent regulation of the light-activated cation channel TRP.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(12):1668-70.
2002: Bernhard Kühn; Constantin Christel; Thomas Wieland; Günter Schultz; Thomas Gudermann
G-protein betagamma-subunits contribute to the coupling specificity of the beta2-adrenergic receptor to G(s).
Naunyn-Schmiedeberg's archives of pharmacology 2002;365(3):231-41.
2002: Silke Jung; Rainer Strotmann; Günter Schultz; Tim D Plant
TRPC6 is a candidate channel involved in receptor-stimulated cation currents in A7r5 smooth muscle cells.
American journal of physiology. Cell physiology 2002;282(2):C347-59.
2002: Michael Schaefer; Tim D Plant; Nicole Stresow; Nadine Albrecht; Günter Schultz
Functional differences between TRPC4 splice variants.
The Journal of biological chemistry 2002;277(5):3752-9.
2001: S Weitmann; Günter Schultz; Christiane Kleuss
Adenylyl cyclase type II domains involved in Gbetagamma stimulation.
Biochemistry 2001;40(36):10853-8.
2001: Michael Schaefer; Nadine Albrecht; T Hofmann; Thomas Gudermann; Günter Schultz
Diffusion-limited translocation mechanism of protein kinase C isotypes.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(9):1634-6.
2001: Hans Peter Reusch; Michael Schaefer; Claudia Plum; Günter Schultz; Martin Paul
Gbeta gamma mediate differentiation of vascular smooth muscle cells.
The Journal of biological chemistry 2001;276(22):19540-7.
2001: Alexandra Zywietz; A Gohla; M Schmelz; Günter Schultz; Stefan Offermanns
Pleiotropic effects of Pasteurella multocida toxin are mediated by Gq-dependent and -independent mechanisms. involvement of Gq but not G11.
The Journal of biological chemistry 2001;276(6):3840-5.
2000: Angela Schulz; Karsten Bruns; Peter Henklein; Gerd Krause; Mario Schubert; Thomas Gudermann; Victor Wray; Günter Schultz; Torsten Schöneberg
Requirement of specific intrahelical interactions for stabilizing the inactive conformation of glycoprotein hormone receptors.
The Journal of biological chemistry 2000;275(48):37860-9.
2000: A Abel; N Wittau; Thomas Wieland; Günter Schultz; F Kalkbrenner
Cell cycle-dependent coupling of the vasopressin V1a receptor to different G proteins.
The Journal of biological chemistry 2000;275(42):32543-51.
2000: Rainer Strotmann; Christian Harteneck; K Nunnenmacher; Günter Schultz; Tim D Plant
OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity.
Nature cell biology 2000;2(10):695-702.
2000: Thomas Hofmann; Michael Schaefer; Günter Schultz; Thomas Gudermann
Cloning, expression and subcellular localization of two novel splice variants of mouse transient receptor potential channel 2.
The Biochemical journal 2000;351(Pt 1):115-22.
2000: N Wittau; Robert Grosse; F Kalkbrenner; A Gohla; Günter Schultz; Thomas Gudermann
The galanin receptor type 2 initiates multiple signaling pathways in small cell lung cancer cells by coupling to G(q), G(i) and G(12) proteins.
Oncogene 2000;19(37):4199-209.
2000: A Gohla; Günter Schultz; Stefan Offermanns
Role for G(12)/G(13) in agonist-induced vascular smooth muscle cell contraction.
Circulation research 2000;87(3):221-7.
2000: Michael Schaefer; Tim D Plant; AG Obukhov; Thomas Hofmann; Thomas Gudermann; Günter Schultz
Receptor-mediated regulation of the nonselective cation channels TRPC4 and TRPC5.
The Journal of biological chemistry 2000;275(23):17517-26.
2000: Thomas Gudermann; Robert Grosse; Günter Schultz
Contribution of receptor/G protein signaling to cell growth and transformation.
Naunyn-Schmiedeberg's archives of pharmacology 2000;361(4):345-62.
2000: Christian Harteneck; Tim D Plant; Günter Schultz
From worm to man: three subfamilies of TRP channels.
Trends in neurosciences 2000;23(4):159-66.
2000: Robert Grosse; A Schmid; Torsten Schöneberg; A Herrlich; P Muhn; Günter Schultz; Thomas Gudermann
Gonadotropin-releasing hormone receptor initiates multiple signaling pathways by exclusively coupling to G(q/11) proteins.
The Journal of biological chemistry 2000;275(13):9193-200.
2000: Angela Schulz; Robert Grosse; Günter Schultz; Thomas Gudermann; Torsten Schöneberg
Structural implication for receptor oligomerization from functional reconstitution studies of mutant V2 vasopressin receptors.
The Journal of biological chemistry 2000;275(4):2381-9.
2000: T Hofmann; M Schaefer; Günter Schultz; Thomas Gudermann
Transient receptor potential channels as molecular substrates of receptor-mediated cation entry.
Journal of molecular medicine (Berlin, Germany) 2000;78(1):14-25.
1999: Torsten Schöneberg; Angela Schulz; Robert Grosse; Rüdiger Schade; Peter Henklein; Günter Schultz; Thomas Gudermann
A novel subgroup of class I G-protein-coupled receptors.
Biochimica et biophysica acta 1999;1446(1-2):57-70.
1999: A Gohla; Stefan Offermanns; Thomas Wilkie; Günter Schultz
Differential involvement of Galpha12 and Galpha13 in receptor-mediated stress fiber formation.
The Journal of biological chemistry 1999;274(25):17901-7.
1999: Torsten Schöneberg; Günter Schultz; Thomas Gudermann
Structural basis of G protein-coupled receptor function.
Molecular and cellular endocrinology 1999;151(1-2):181-93.
1999: B Klages; U Brandt; M I Simon; Günter Schultz; Stefan Offermanns
Activation of G12/G13 results in shape change and Rho/Rho-kinase-mediated myosin light chain phosphorylation in mouse platelets.
The Journal of cell biology 1999;144(4):745-54.
1999: F Kalkbrenner; A Abel; N Wittau; Günter Schultz
Promiscuity and fidelity in receptor-G-protein coupling: cell cycle-dependent coupling of the vasopressin V1 receptor.
Biochemical Society transactions 1999;27(2):158-63.
1999: Angela Schulz; Torsten Schöneberg; R Paschke; Günter Schultz; Thomas Gudermann
Role of the third intracellular loop for the activation of gonadotropin receptors.
Molecular endocrinology (Baltimore, Md.) 1999;13(2):181-90.
1999: Thomas Hofmann; AG Obukhov; Michael Schaefer; Christian Harteneck; Thomas Gudermann; Günter Schultz
Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol.
Nature 1999;397(6716):259-63.
1998: Andreas Friebe; Florian Müllershausen; A Smolenski; U Walter; Günter Schultz; Doris Koesling
YC-1 potentiates nitric oxide- and carbon monoxide-induced cyclic GMP effects in human platelets.
Molecular pharmacology 1998;54(6):962-7.
1998: Heike Biebermann; Torsten Schöneberg; Angela Schulz; Gerd Krause; Annette Grüters; Günter Schultz; Thomas Gudermann
A conserved tyrosine residue (Y601) in transmembrane domain 5 of the human thyrotropin receptor serves as a molecular switch to determine G-protein coupling.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1998;12(14):1461-71.
1998: Andreas Friebe; Günter Schultz; Doris Koesling
Stimulation of soluble guanylate cyclase by superoxide dismutase is mediated by NO.
The Biochemical journal 1998;335 ( Pt 3)():527-31.
1998: A Herrlich; Henrik Daub; Axel Knebel; Peter Herrlich; Axel Ullrich; Günter Schultz; Thomas Gudermann
Ligand-independent activation of platelet-derived growth factor receptor is a necessary intermediate in lysophosphatidic, acid-stimulated mitogenic activity in L cells.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(15):8985-90.
1998: AG Obukhov; Günter Schultz; Andreas Lückhoff
Regulation of heterologously expressed transient receptor potential-like channels by calcium ions.
Neuroscience 1998;85(2):487-95.
1998: M Schaefer; T Hofmann; Günter Schultz; Thomas Gudermann
A new prostaglandin E receptor mediates calcium influx and acrosome reaction in human spermatozoa.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(6):3008-13.
1998: A Gohla; R Harhammer; Günter Schultz
The G-protein G13 but not G12 mediates signaling from lysophosphatidic acid receptor via epidermal growth factor receptor to Rho.
The Journal of biological chemistry 1998;273(8):4653-9.
1998: Torsten Schöneberg; Angela Schulz; Heike Biebermann; Annette Grüters; T Grimm; K Hübschmann; Guido Filler; Thomas Gudermann; Günter Schultz
V2 vasopressin receptor dysfunction in nephrogenic diabetes insipidus caused by different molecular mechanisms.
Human mutation 1998;12(3):196-205.
1998: Vadim Degtiar; Burghardt Wittig; Günter Schultz; F Kalkbrenner
Microinjection of antisense oligonucleotides and electrophysiological recording of whole-cell currents as tools to identify specific G-protein subtypes coupling hormone receptors to voltage-gated calcium channels.
Methods in molecular biology (Clifton, N.J.) 1998;84():123-36.
1997: Christof Zitt; AG Obukhov; C Strübing; A Zobel; F Kalkbrenner; Andreas Lückhoff; Günter Schultz
Expression of TRPC3 in Chinese hamster ovary cells results in calcium-activated cation currents not related to store depletion.
The Journal of cell biology 1997;138(6):1333-41.
1997: Torsten Schöneberg; V Sandig; J Wess; Thomas Gudermann; Günter Schultz
Reconstitution of mutant V2 vasopressin receptors by adenovirus-mediated gene transfer. Molecular basis and clinical implication.
The Journal of clinical investigation 1997;100(6):1547-56.
1997: Robert Grosse; Torsten Schöneberg; Günter Schultz; Thomas Gudermann
Inhibition of gonadotropin-releasing hormone receptor signaling by expression of a splice variant of the human receptor.
Molecular endocrinology (Baltimore, Md.) 1997;11(9):1305-18.
1997: Andreas Friebe; B Wedel; Christian Harteneck; John Foerster; Günter Schultz; Doris Koesling
Functions of conserved cysteines of soluble guanylyl cyclase.
Biochemistry 1997;36(6):1194-8.
1997: Thomas Gudermann; F Kalkbrenner; E Dippel; K L Laugwitz; Günter Schultz
Specificity and complexity of receptor-G-protein interaction.
Advances in second messenger and phosphoprotein research 1997;31():253-62.
1997: F Kalkbrenner; E Dippel; Matthias Schroff; Burghardt Wittig; Günter Schultz
Nuclear application of antisense oligonucleotides by microinjection and ballistomagnetic transfer to identify G protein heterotrimers activating phospholipase C.
Methods in molecular biology (Clifton, N.J.) 1997;83():203-16.
1996: Andreas Friebe; Günter Schultz; Doris Koesling
Sensitizing soluble guanylyl cyclase to become a highly CO-sensitive enzyme.
The EMBO journal 1996;15(24):6863-8.
1996: R Harhammer; A Gohla; Günter Schultz
Interaction of G protein Gbetagamma dimers with small GTP-binding proteins of the Rho family.
FEBS letters 1996;399(3):211-4.
1996: B Kühn; A Schmid; Christian Harteneck; Thomas Gudermann; Günter Schultz
G proteins of the Gq family couple the H2 histamine receptor to phospholipase C.
Molecular endocrinology (Baltimore, Md.) 1996;10(12):1697-707.
1996: F Kalkbrenner; Edgar Dippel; Burghardt Wittig; Günter Schultz
Specificity of interaction between receptor and G protein: use of antisense techniques to relate G-protein subunits to function.
Biochimica et biophysica acta 1996;1314(1-2):125-39.
1996: AG Obukhov; Christian Harteneck; A Zobel; R Harhammer; F Kalkbrenner; D Leopoldt; Andreas Lückhoff; Bernd Nürnberg; Günter Schultz
Direct activation of trpl cation channels by G alpha11 subunits.
The EMBO journal 1996;15(21):5833-8.
1996: R Harhammer; Bernd Nürnberg; Christian Harteneck; D Leopoldt; T Exner; Günter Schultz
Distinct biochemical properties of the native members of the G12 G-protein subfamily. Characterization of G alpha 12 purified from rat brain.
The Biochemical journal 1996;319 ( Pt 1)():165-71.
1996: John Foerster; Christian Harteneck; J Malkewitz; Günter Schultz; Doris Koesling
A functional heme-binding site of soluble guanylyl cyclase requires intact N-termini of alpha 1 and beta 1 subunits.
European journal of biochemistry / FEBS 1996;240(2):380-6.
1996: A Herrlich; B Kühn; Robert Grosse; A Schmid; Günter Schultz; Thomas Gudermann
Involvement of Gs and Gi proteins in dual coupling of the luteinizing hormone receptor to adenylyl cyclase and phospholipase C.
The Journal of biological chemistry 1996;271(28):16764-72.
1996: Andreas Friebe; J Malkewitz; Günter Schultz; Doris Koesling
Positive effects of pollution.
Nature 1996;382(6587):120.
1996: C Zitt; A Zobel; AG Obukhov; Christian Harteneck; F Kalkbrenner; Andreas Lückhoff; Günter Schultz
Cloning and functional expression of a human Ca2+-permeable cation channel activated by calcium store depletion.
Neuron 1996;16(6):1189-96.
1996: G Anhert-Hilger; A Stadtbäumer; C Strübing; Hans Scherübl; Günter Schultz; Ernst-Otto Riecken; Bertram Wiedenmann
gamma-Aminobutyric acid secretion from pancreatic neuroendocrine cells.
Gastroenterology 1996;110(5):1595-604.
1996: Edgar Dippel; F Kalkbrenner; Burghardt Wittig; Günter Schultz
A heterotrimeric G protein complex couples the muscarinic m1 receptor to phospholipase C-beta.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(4):1391-6.
1996: Vadim Degtiar; Burghardt Wittig; Günter Schultz; F Kalkbrenner
A specific G(o) heterotrimer couples somatostatin receptors to voltage-gated calcium channels in RINm5F cells.
FEBS letters 1996;380(1-2):137-41.
1996: K L Laugwitz; A Allgeier; Stefan Offermanns; Karsten Spicher; Jacqueline Van Sande; Jacques E Dumont; Günter Schultz
The human thyrotropin receptor: a heptahelical receptor capable of stimulating members of all four G protein families.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(1):116-20.
1995: Philippe Ohlmann; K L Laugwitz; Bernd Nürnberg; Karsten Spicher; Günter Schultz; Jean-Pierre Cazenave; Christian Gachet
The human platelet ADP receptor activates Gi2 proteins.
The Biochemical journal 1995;312 ( Pt 3)():775-9.
1995: AG Obukhov; S V Jones; Vadim Degtiar; Andreas Lückhoff; Günter Schultz; Jürgen Hescheler
Ca(2+)-permeable large-conductance nonselective cation channels in rat basophilic leukemia cells.
The American journal of physiology 1995;269(5 Pt 1):C1119-25.
1995: B Wedel; Christian Harteneck; John Foerster; Andreas Friebe; Günter Schultz; Doris Koesling
Functional domains of soluble guanylyl cyclase.
The Journal of biological chemistry 1995;270(42):24871-5.
1995: F Kalkbrenner; Vadim Degtiar; M Schenker; S Brendel; A Zobel; J Heschler; Burghardt Wittig; Günter Schultz
Subunit composition of G(o) proteins functionally coupling galanin receptors to voltage-gated calcium channels.
The EMBO journal 1995;14(19):4728-37.
1995: S Behrends; Christian Harteneck; Günter Schultz; Doris Koesling
A variant of the alpha 2 subunit of soluble guanylyl cyclase contains an insert homologous to a region within adenylyl cyclases and functions as a dominant negative protein.
The Journal of biological chemistry 1995;270(36):21109-13.
1995: Ian F Musgrave; D Krautwurst; Jürgen Hescheler; Günter Schultz
Clonidine and cirazoline inhibit activation of nicotinic channels in PC-12 cells.
Annals of the New York Academy of Sciences 1995;763():272-82.
1995: A Hagelüken; L Grünbaum; JF Klinker; Bernd Nürnberg; R Harhammer; Günter Schultz; C Leschke; Walter Schunack; Roland Seifert
Histamine receptor-dependent and/or -independent activation of guanine nucleotide-binding proteins by histamine and 2-substituted histamine derivatives in human leukemia (HL-60) and human erythroleukemia (HEL) cells.
Biochemical pharmacology 1995;49(7):901-914.
1995: I Schwaner; Stefan Offermanns; Karsten Spicher; Roland Seifert; Günter Schultz
Differential activation of Gi and Gs proteins by E- and I-type prostaglandins in membranes from the human erythroleukaemia cell line, HEL.
Biochimica et biophysica acta 1995;1265(1):8-14.
1995: Christian Harteneck; AG Obukhov; A Zobel; F Kalkbrenner; Günter Schultz
The Drosophila cation channel trpl expressed in insect Sf9 cells is stimulated by agonists of G-protein-coupled receptors.
FEBS letters 1995;358(3):297-300.
1994: R Harhammer; Bernd Nürnberg; Karsten Spicher; Günter Schultz
Rapid isolation of G alpha 13 from bovine brain membranes: supportive effect of ethylene glycol.
Biochemical and biophysical research communications 1994;204(2):835-40.
1994: R Harhammer; Bernd Nürnberg; Karsten Spicher; Günter Schultz
Purification of the G-protein G13 from rat brain membranes.
The Biochemical journal 1994;303 ( Pt 1)():135-40.
1994: Gudrun Ahnert-Hilger; T Schäfer; Karsten Spicher; Christine Grund; Günter Schultz; Bertram Wiedenmann
Detection of G-protein heterotrimers on large dense core and small synaptic vesicles of neuroendocrine and neuronal cells.
European journal of cell biology 1994;65(1):26-38.
1994: Stefan Offermanns; Günter Schultz
Complex information processing by the transmembrane signaling system involving G proteins.
Naunyn-Schmiedeberg's archives of pharmacology 1994;350(4):329-38.
1994: Jürgen Hescheler; Günter Schultz
Heterotrimeric G proteins involved in the modulation of voltage-dependent calcium channels of neuroendocrine cells.
Annals of the New York Academy of Sciences 1994;733():306-12.
1994: Stefan Offermanns; E Heiler; Karsten Spicher; Günter Schultz
Gq and G11 are concurrently activated by bombesin and vasopressin in Swiss 3T3 cells.
FEBS letters 1994;349(2):201-4.
1994: Ian F Musgrave; Roland Seifert; Günter Schultz
Maitotoxin activates cation channels distinct from the receptor-activated non-selective cation channels of HL-60 cells.
The Biochemical journal 1994;301 ( Pt 2)():437-41.
1994: M Berg; Stefan Offermanns; Roland Seifert; Günter Schultz
Synthetic lipopeptide Pam3CysSer(Lys)4 is an effective activator of human platelets.
The American journal of physiology 1994;266(6 Pt 1):C1684-91.
1994: Bernd Nürnberg; Karsten Spicher; R Harhammer; A Bosserhoff; R Frank; H Hilz; Günter Schultz
Purification of a novel G-protein alpha 0-subtype from mammalian brain.
The Biochemical journal 1994;300 ( Pt 2)():387-94.
1994: A Allgeier; Stefan Offermanns; Jacqueline Van Sande; Karsten Spicher; Günter Schultz; Jacques E Dumont
The human thyrotropin receptor activates G-proteins Gs and Gq/11.
The Journal of biological chemistry 1994;269(19):13733-5.
1994: Stefan Offermanns; Thomas Wieland; D Homann; J Sandmann; E Bombien; Karsten Spicher; Günter Schultz; K H Jakobs
Transfected muscarinic acetylcholine receptors selectively couple to Gi-type G proteins and Gq/11.
Molecular pharmacology 1994;45(5):890-8.
1994: Roland Seifert; L Grünbaum; Günter Schultz
Histamine H1-receptors in HL-60 monocytes are coupled to Gi-proteins and pertussis toxin-insensitive G-proteins and mediate activation of Ca2+ influx without concomitant Ca2+ mobilization from intracellular stores.
Naunyn-Schmiedeberg's archives of pharmacology 1994;349(4):355-61.
1994: Stefan Offermanns; Günter Schultz
What are the functions of the pertussis toxin-insensitive G proteins G12, G13 and Gz?
Molecular and cellular endocrinology 1994;100(1-2):71-4.
1994: Roland Seifert; A Hagelüken; A Höer; D Höer; L Grünbaum; Stefan Offermanns; I Schwaner; V Zingel; Walter Schunack; Günter Schultz
The H1 receptor agonist 2-(3-chlorophenyl)histamine activates Gi proteins in HL-60 cells through a mechanism that is independent of known histamine receptor subtypes.
Molecular pharmacology 1994;45(4):578-86.
1994: B Wedel; P Humbert; Christian Harteneck; John Foerster; J Malkewitz; E Böhme; Günter Schultz; Doris Koesling
Mutation of His-105 in the beta 1 subunit yields a nitric oxide-insensitive form of soluble guanylyl cyclase.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(7):2592-6.
1994: D Krautwurst; Vadim Degtiar; Günter Schultz; Jürgen Hescheler
The isoquinoline derivative LOE 908 selectively blocks vasopressin-activated nonselective cation currents in A7r5 aortic smooth muscle cells.
Naunyn-Schmiedeberg's archives of pharmacology 1994;349(3):301-7.
1994: Karsten Spicher; F Kalkbrenner; A Zobel; R Harhammer; Bernd Nürnberg; A Söling; Günter Schultz
G12 and G13 alpha-subunits are immunochemically detectable in most membranes of various mammalian cells and tissues.
Biochemical and biophysical research communications 1994;198(3):906-14.
1994: Michael Veit; Bernd Nürnberg; Karsten Spicher; Christian Harteneck; Evgeni Ponimaskin; Günter Schultz; Michael F G Schmidt
The alpha-subunits of G-proteins G12 and G13 are palmitoylated, but not amidically myristoylated.
FEBS letters 1994;339(1-2):160-4.
1994: M Naim; Roland Seifert; Bernd Nürnberg; L Grünbaum; Günter Schultz
Some taste substances are direct activators of G-proteins.
The Biochemical journal 1994;297 ( Pt 3)():451-4.
1994: Stefan Offermanns; K L Laugwitz; Karsten Spicher; Günter Schultz
G proteins of the G12 family are activated via thromboxane A2 and thrombin receptors in human platelets.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(2):504-8.
1994: Stefan Offermanns; S V Jones; E Bombien; Günter Schultz
Stimulation of mitogen-activated protein kinase activity by different secretory stimuli in rat basophilic leukemia cells.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(1):250-61.
1994: Christiane Kleuss; Günter Schultz; Burghardt Wittig
Microinjection of antisense oligonucleotides to assess G-protein subunit function.
Methods in enzymology 1994;237():345-55.
1994: K L Laugwitz; Karsten Spicher; Günter Schultz; Stefan Offermanns
Identification of receptor-activated G proteins: selective immunoprecipitation of photolabeled G-protein alpha subunits.
Methods in enzymology 1994;237():283-94.
1993: P Friederich; Bernd Nürnberg; Günter Schultz; Jürgen Hescheler
Inversion of Ca2+ current modulation during recovery of neuroblastoma cells from pertussis toxin pretreatment.
FEBS letters 1993;334(3):322-6.
1993: Stefan Offermanns; E Bombien; Günter Schultz
Stimulation of tyrosine phosphorylation and mitogen-activated-protein (MAP) kinase activity in human SH-SY5Y neuroblastoma cells by carbachol.
The Biochemical journal 1993;294 ( Pt 2)():545-50.
1993: Maik Gollasch; Christiane Kleuss; Jürgen Hescheler; Burghardt Wittig; Günter Schultz
Gi2 and protein kinase C are required for thyrotropin-releasing hormone-induced stimulation of voltage-dependent Ca2+ channels in rat pituitary GH3 cells.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(13):6265-9.
1993: D Krautwurst; Jürgen Hescheler; D Arndts; W Lösel; R Hammer; Günter Schultz
Novel potent inhibitor of receptor-activated nonselective cation currents in HL-60 cells.
Molecular pharmacology 1993;43(5):655-9.
1993: Stefan Offermanns; E Bombien; Günter Schultz
Thrombin Ca(2+)-dependently stimulates protein tyrosine phosphorylation in BC3H1 muscle cells.
The Biochemical journal 1993;290 ( Pt 1)():27-32.
1993: Christiane Kleuss; Hans Scherübl; Jürgen Hescheler; Günter Schultz; Burghardt Wittig
Selectivity in signal transduction determined by gamma subunits of heterotrimeric G proteins.
Science (New York, N.Y.) 1993;259(5096):832-4.
1993: K L Laugwitz; Stefan Offermanns; Karsten Spicher; Günter Schultz
mu and delta opioid receptors differentially couple to G protein subtypes in membranes of human neuroblastoma SH-SY5Y cells.
Neuron 1993;10(2):233-42.
1993: D Krautwurst; Hans Scherübl; T Kleppisch; Jürgen Hescheler; Günter Schultz
Dihydropyridine binding and Ca(2+)-channel characterization in clonal calcitonin-secreting cells.
The Biochemical journal 1993;289 ( Pt 3)():659-65.
1993: Jürgen Hescheler; Günter Schultz
Nonselective cation channels: physiological and pharmacological modulations of channel activity.
EXS 1993;66():27-43.
1992: D Krautwurst; Roland Seifert; Jürgen Hescheler; Günter Schultz
Formyl peptides and ATP stimulate Ca2+ and Na+ inward currents through non-selective cation channels via G-proteins in dibutyryl cyclic AMP-differentiated HL-60 cells. Involvement of Ca2+ and Na+ in the activation of beta-glucuronidase release and superoxide production.
The Biochemical journal 1992;288 ( Pt 3)():1025-35.
1992: Stefan Offermanns; Günter Schultz
Tyrosine phosphorylation is an early and requisite signal induced by interferon-gamma in HL-60 cells.
FEBS letters 1992;310(3):260-4.
1992: Christiane Kleuss; Hans Scherübl; Jürgen Hescheler; Günter Schultz; Burghardt Wittig
Different beta-subunits determine G-protein interaction with transmembrane receptors.
Nature 1992;358(6385):424-6.
1992: Karsten Spicher; B Nuernberg; B Jäger; W Rosenthal; Günter Schultz
Heterogeneity of three electrophoretically distinct Go alpha-subunits in mammalian brain.
FEBS letters 1992;307(2):215-8.
1992: F J Klinz; Roland Seifert; I Schwaner; H Gausepohl; R Frank; Günter Schultz
Generation of specific antibodies against the rap1A, rap1B and rap2 small GTP-binding proteins. Analysis of rap and ras proteins in membranes from mammalian cells.
European journal of biochemistry / FEBS 1992;207(1):207-13.
1992: T Kleppisch; Gudrun Ahnert-Hilger; Maik Gollasch; Karsten Spicher; Jürgen Hescheler; Günter Schultz; W Rosenthal
Inhibition of voltage-dependent Ca2+ channels via alpha 2-adrenergic and opioid receptors in cultured bovine adrenal chromaffin cells.
Pflügers Archiv : European journal of physiology 1992;421(2-3):131-7.
1992: Stefan Offermanns; Roland Seifert; J W Metzger; G Jung; A Lieberknecht; U Schmidt; Günter Schultz
Lipopeptides are effective stimulators of tyrosine phosphorylation in human myeloid cells.
The Biochemical journal 1992;282 ( Pt 2)():551-7.
1992: I Schwaner; Roland Seifert; Günter Schultz
Receptor-mediated increases in cytosolic Ca2+ in the human erythroleukaemia cell line involve pertussis toxin-sensitive and -insensitive pathways.
The Biochemical journal 1992;281 ( Pt 2)():301-7.
1992: I Schwaner; Roland Seifert; Günter Schultz
The prostacyclin analogues, cicaprost and iloprost, increase cytosolic Ca2+ concentration in the human erythroleukemia cell line, HEL, via pertussis toxin-insensitive G-proteins.
Eicosanoids 1992;5 Suppl():S10-2.
1991: Jürgen Hescheler; R Meyer; S Plant; D Krautwurst; W Rosenthal; Günter Schultz
Morphological, biochemical, and electrophysiological characterization of a clonal cell (H9c2) line from rat heart.
Circulation research 1991;69(6):1476-86.
1991: Maik Gollasch; Hermann Haller; Günter Schultz; Jürgen Hescheler
Thyrotropin-releasing hormone induces opposite effects on Ca2+ channel currents in pituitary cells by two pathways.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(22):10262-6.
1991: Christian Harteneck; B Wedel; Doris Koesling; J Malkewitz; E Böhme; Günter Schultz
Molecular cloning and expression of a new alpha-subunit of soluble guanylyl cyclase. Interchangeability of the alpha-subunits of the enzyme.
FEBS letters 1991;292(1-2):217-22.
1991: Doris Koesling; E Böhme; Günter Schultz
Guanylyl cyclases, a growing family of signal-transducing enzymes.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1991;5(13):2785-91.
1991: Christiane Kleuss; Jürgen Hescheler; C Ewel; W Rosenthal; Günter Schultz; Burghardt Wittig
Assignment of G-protein subtypes to specific receptors inducing inhibition of calcium currents.
Nature 1991;353(6339):43-8.
1991: Bernd Mayer; M John; B Heinzel; E R Werner; H Wachter; Günter Schultz; E Böhme
Brain nitric oxide synthase is a biopterin- and flavin-containing multi-functional oxido-reductase.
FEBS letters 1991;288(1-2):187-91.
1991: Stefan Offermanns; Maik Gollasch; Jürgen Hescheler; Karsten Spicher; A Schmidt; Günter Schultz; W Rosenthal
Inhibition of voltage-dependent Ca2+ currents and activation of pertussis toxin-sensitive G-proteins via muscarinic receptors in GH3 cells.
Molecular endocrinology (Baltimore, Md.) 1991;5(7):995-1002.
1991: Maik Gollasch; Jürgen Hescheler; Karsten Spicher; F J Klinz; Günter Schultz; W Rosenthal
Inhibition of Ca2+ channels via alpha 2-adrenergic and muscarinic receptors in pheochromocytoma (PC-12) cells.
The American journal of physiology 1991;260(6 Pt 1):C1282-9.
1991: J Ervens; Günter Schultz; Roland Seifert
Differential inhibition and potentiation of chemoattractant-induced superoxide formation in human neutrophils by the cell-permeant analogue of cyclic GMP, N2,2'-O-dibutyryl guanosine 3':5'-cyclic monophosphate.
Naunyn-Schmiedeberg's archives of pharmacology 1991;343(4):370-6.
1991: Doris Koesling; Günter Schultz; E Böhme
Sequence homologies between guanylyl cyclases and structural analogies to other signal-transducing proteins.
FEBS letters 1991;280(2):301-6.
1991: Karsten Spicher; F J Klinz; U Rudolph; J Codina; Lutz Birnbaumer; Günter Schultz; W Rosenthal
Identification of the G-protein alpha-subunit encoded by alpha o2 cDNA as a 39 kDa pertussis toxin substrate.
Biochemical and biophysical research communications 1991;175(2):473-9.
1991: Stefan Offermanns; Günter Schultz; W Rosenthal
Evidence for opioid receptor-mediated activation of the G-proteins, Go and Gi2, in membranes of neuroblastoma x glioma (NG108-15) hybrid cells.
The Journal of biological chemistry 1991;266(6):3365-8.
1991: J Ervens; Günter Schultz; Roland Seifert
Differential regulation of chemoattractant-induced superoxide formation in human neutrophils by cell-permeant analogues of cyclic AMP and cyclic GMP.
Biochemical Society transactions 1991;19(1):59-63.
1991: P Humbert; F Niroomand; G Fischer; Bernd Mayer; Doris Koesling; Klaus-Dieter Hinsch; Günter Schultz; E Böhme
Preparation of soluble guanylyl cyclase from bovine lung by immunoaffinity chromatography.
Methods in enzymology 1991;195():384-91.
1991: Roland Seifert; Günter Schultz
The superoxide-forming NADPH oxidase of phagocytes. An enzyme system regulated by multiple mechanisms.
Reviews of physiology, biochemistry and pharmacology 1991;117():1-338.
1991: B Hoffmann; C Seib; A Höer; D Höer; E Oberdisse; W Rosenthal; Günter Schultz
Improved purification and characterization of membraneous and cytosolic inositol phospholipid-specific phospholipases C from porcine brain cortex.
Biomedica biochimica acta 1991;50(1):31-46.
1990: Christian Harteneck; Doris Koesling; A Söling; Günter Schultz; E Böhme
Expression of soluble guanylyl cyclase. Catalytic activity requires two enzyme subunits.
FEBS letters 1990;272(1-2):221-3.
1990: P Humbert; F Niroomand; G Fischer; Bernd Mayer; Doris Koesling; Klaus-Dieter Hinsch; H Gausepohl; R Frank; Günter Schultz; E Böhme
Purification of soluble guanylyl cyclase from bovine lung by a new immunoaffinity chromatographic method.
European journal of biochemistry / FEBS 1990;190(2):273-8.
1990: Doris Koesling; Christian Harteneck; P Humbert; A Bosserhoff; R Frank; Günter Schultz; E Böhme
The primary structure of the larger subunit of soluble guanylyl cyclase from bovine lung. Homology between the two subunits of the enzyme.
FEBS letters 1990;266(1-2):128-32.
1990: Roland Seifert; Günter Schultz; M Richter-Freund; J Metzger; K H Wiesmüller; G Jung; Wolfgang G Bessler; Sunna Hauschildt
Activation of superoxide formation and lysozyme release in human neutrophils by the synthetic lipopeptide Pam3Cys-Ser-(Lys)4. Involvement of guanine-nucleotide-binding proteins and synergism with chemotactic peptides.
The Biochemical journal 1990;267(3):795-802.
1990: S Offermans; R Schäfer; B Hoffmann; E Bombien; Karsten Spicher; Klaus-Dieter Hinsch; Günter Schultz; W Rosenthal
Agonist-sensitive binding of a photoreactive GTP analog to a G-protein alpha-subunit in membranes of HL-60 cells.
FEBS letters 1990;260(1):14-8.
1990: W Rosenthal; Jürgen Hescheler; R Eckert; Stefan Offermanns; A Schmidt; Klaus-Dieter Hinsch; Karsten Spicher; W Trautwein; Günter Schultz
Pertussis toxin-sensitive G-proteins: participation in the modulation of voltage-dependent Ca2+ channels by hormones and neurotransmitters.
Advances in second messenger and phosphoprotein research 1990;24():89-94.
1990: Günter Schultz; W Rosenthal; J Hescheler; W Trautwein
Role of G proteins in calcium channel modulation.
Annual review of physiology 1990;52():275-92.
1989: R Burde; Roland Seifert; A Buschauer; Günter Schultz
Histamine inhibits activation of human neutrophils and HL-60 leukemic cells via H2-receptors.
Naunyn-Schmiedeberg's archives of pharmacology 1989;340(6):671-8.
1989: Klaus-Dieter Hinsch; I Tychowiecka; H Gausepohl; R Frank; W Rosenthal; Günter Schultz
Tissue distribution of beta 1- and beta 2-subunits of regulatory guanine nucleotide-binding proteins.
Biochimica et biophysica acta 1989;1013(1):60-7.
1989: U Rudolph; Günter Schultz; W Rosenthal
The cytosolic G-protein alpha-subunit in human neutrophils responds to treatment with guanine nucleotides and magnesium.
FEBS letters 1989;251(1-2):137-42.
1989: Roland Seifert; R Burde; Günter Schultz
Lack of effect of opioid peptides, morphine and naloxone on superoxide formation in human neutrophils and HL-60 leukemic cells.
Naunyn-Schmiedeberg's archives of pharmacology 1989;340(1):101-6.
1989: Roland Seifert; P Jungblut; Günter Schultz
Differential expression of cytosolic activation factors for NADPH oxidase in HL-60 leukemic cells.
Biochemical and biophysical research communications 1989;161(3):1109-17.
1989: Roland Seifert; R Burde; Günter Schultz
Activation of NADPH oxidase by purine and pyrimidine nucleotides involves G proteins and is potentiated by chemotactic peptides.
The Biochemical journal 1989;259(3):813-9.
1989: U Rudolph; Doris Koesling; Klaus-Dieter Hinsch; R Seifert; M Bigalke; Günter Schultz; W Rosenthal
G-protein alpha-subunits in cytosolic and membranous fractions of human neutrophils.
Molecular and cellular endocrinology 1989;63(1-2):143-53.
1989: Roland Seifert; K Wenzel; F Eckstein; Günter Schultz
Purine and pyrimidine nucleotides potentiate activation of NADPH oxidase and degranulation by chemotactic peptides and induce aggregation of human neutrophils via G proteins.
European journal of biochemistry / FEBS 1989;181(1):277-85.
1989: Stefan Offermanns; Günter Schultz; W Rosenthal
Secretion-stimulating and secretion-inhibiting hormones stimulate high-affinity pertussis-toxin-sensitive GTPases in membranes of a pituitary cell line.
European journal of biochemistry / FEBS 1989;180(2):283-7.
1988: Karsten Spicher; Klaus-Dieter Hinsch; H Gausepohl; R Frank; W Rosenthal; Günter Schultz
Immunochemical detection of the alpha-subunit of the G-protein, GZ, in membranes and cytosols of mammalian cells.
Biochemical and biophysical research communications 1988;157(3):883-90.
1988: Doris Koesling; Joachim Herz; H Gausepohl; F Niroomand; Klaus-Dieter Hinsch; A Mülsch; E Böhme; Günter Schultz; R Frank
The primary structure of the 70 kDa subunit of bovine soluble guanylate cyclase.
FEBS letters 1988;239(1):29-34.
1988: Klaus-Dieter Hinsch; W Rosenthal; Karsten Spicher; T Binder; H Gausepohl; R Frank; Günter Schultz; Hans-Georg Joost
Adipocyte plasma membranes contain two Gi subtypes but are devoid of Go.
FEBS letters 1988;238(1):191-6.
1988: W Rosenthal; Jürgen Hescheler; W Trautwein; Günter Schultz
Control of voltage-dependent Ca2+ channels by G protein-coupled receptors.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1988;2(12):2784-90.
1988: D Höer; A Kwiatkowski; C Seib; W Rosenthal; Günter Schultz; E Oberdisse
Degradation of inositol 1,3,4,5-tetrakisphosphates by porcine brain cytosol yields inositol 1,3,4-trisphosphate and inositol 1,4,5-trisphosphate.
Biochemical and biophysical research communications 1988;154(2):668-75.
1988: Roland Seifert; C Schächtele; W Rosenthal; Günter Schultz
Activation of protein kinase C by cis- and trans-fatty acids and its potentiation by diacylglycerol.
Biochemical and biophysical research communications 1988;154(1):20-6.
1988: Roland Seifert; W Rosenthal; Günter Schultz; Thomas Wieland; P Gierschick; K H Jakobs
The role of nucleoside-diphosphate kinase reactions in G protein activation of NADPH oxidase by guanine and adenine nucleotides.
European journal of biochemistry / FEBS 1988;175(1):51-5.
1988: W Rosenthal; Jürgen Hescheler; Klaus-Dieter Hinsch; Karsten Spicher; W Trautwein; Günter Schultz
Cyclic AMP-independent, dual regulation of voltage-dependent Ca2+ currents by LHRH and somatostatin in a pituitary cell line.
The EMBO journal 1988;7(6):1627-33.
1987: Roland Seifert; C Schächtele; Günter Schultz
Activation of protein kinase C by cis- and trans-octadecadienoic acids in intact human platelets and its potentiation by diacylglycerol.
Biochemical and biophysical research communications 1987;149(2):762-8.
1987: Christiane Kleuss; M Pallast; S Brendel; W Rosenthal; Günter Schultz
Resolution of transducin subunits by chromatography on blue sepharose.
Journal of chromatography 1987;407():281-9.
1987: H J Fülle; D Höer; W Lache; W Rosenthal; Günter Schultz; E Oberdisse
In vitro synthesis of 32P-labelled phosphatidylinositol 4,5-bisphosphate and its hydrolysis by smooth muscle membrane-bound phospholipase C.
Biochemical and biophysical research communications 1987;145(2):673-9.
1986: W Rosenthal; Doris Koesling; U Rudolph; Christiane Kleuss; M Pallast; M Yajima; Günter Schultz
Identification and characterization of the 35-kDa beta subunit of guanine-nucleotide-binding proteins by an antiserum raised against transducin.
European journal of biochemistry / FEBS 1986;158(2):255-63.