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Joachim Schultz

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TOP 3
Karin Winkler; Anita Schultz; Joachim E Schultz
The S-helix determines the signal in a Tsr receptor/adenylyl cyclase reporter.
Hedda U Ferris; Nora Hornig; Michael Hulko; Andrei N Lupas; Jörg Martin; Joachim E Schultz; Kornelius Zeth; Stanislaw Dunin-Horkawicz; Murray Coles
Mechanism of regulation of receptor histidine kinases.
Hedda U Ferris; Stanislaw Dunin-Horkawicz; Laura García Mondéjar; Michael Hulko; Klaus Hantke; Jörg Martin; Joachim E Schultz; Kornelius Zeth; Andrei N Lupas; Murray Coles
The mechanisms of HAMP-mediated signaling in transmembrane receptors.

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All Publications

2012: Karin Winkler; Anita Schultz; Joachim E Schultz
The S-helix determines the signal in a Tsr receptor/adenylyl cyclase reporter.
The Journal of biological chemistry 2012;287(19):15479-88.
2012: Hedda U Ferris; Nora Hornig; Michael Hulko; Andrei N Lupas; Jörg Martin; Joachim E Schultz; Kornelius Zeth; Stanislaw Dunin-Horkawicz; Murray Coles
Mechanism of regulation of receptor histidine kinases.
Structure (London, England : 1993) 2012;20(1):56-66.
2011: Hedda U Ferris; Stanislaw Dunin-Horkawicz; Laura García Mondéjar; Michael Hulko; Klaus Hantke; Jörg Martin; Joachim E Schultz; Kornelius Zeth; Andrei N Lupas; Murray Coles
The mechanisms of HAMP-mediated signaling in transmembrane receptors.
Structure (London, England : 1993) 2011;19(3):378-85.
2011: Klaus Hantke; Karin Winkler; Joachim E Schultz
Escherichia coli exports cyclic AMP via TolC.
Journal of bacteriology 2011;193(5):1086-9.
2011: Joachim E Schultz; Torsten Dunkern; Elvira Gawlitta-Gorka; Gabriele Sorg
The GAF-tandem domain of phosphodiesterase 5 as a potential drug target.
Handbook of experimental pharmacology 2011;(204):151-66.
2010: Kajal Kanchan; Jürgen Linder; Karin Winkler; Klaus Hantke; Anita Schultz; Joachim E Schultz
Transmembrane signaling in chimeras of the Escherichia coli aspartate and serine chemotaxis receptors and bacterial class III adenylyl cyclases.
The Journal of biological chemistry 2010;285(3):2090-9.
2009: Ying Lan Guo; Hermann Mayer; Waldemar Vollmer; Dorothea Dittrich; Peter Sander; Anita Schultz; Joachim E Schultz
Polyphosphates from Mycobacterium bovis--potent inhibitors of class III adenylate cyclases.
The FEBS journal 2009;276(4):1094-103.
2008: Jürgen U Linder; Joachim E Schultz
Versatility of signal transduction encoded in dimeric adenylyl cyclases.
Current opinion in structural biology 2008;18(6):667-72.
2008: Karina Hofbauer; Anita Schultz; Joachim E Schultz
Functional chimeras of the phosphodiesterase 5 and 10 tandem GAF domains.
The Journal of biological chemistry 2008;283(37):25164-70.
2008: Marco Gross-Langenhoff; Arnulf Stenzl; Florian Altenberend; Anita Schultz; Joachim E Schultz
The properties of phosphodiesterase 11A4 GAF domains are regulated by modifications in its N-terminal domain.
The FEBS journal 2008;275(8):1643-50.
2007: Felix Findeisen; Jürgen U Linder; Anita Schultz; Joachim E Schultz; Britta Brügger; Felix T Wieland; Irmgard Sinning; Ivo Tews
The structure of the regulatory domain of the adenylyl cyclase Rv1264 from Mycobacterium tuberculosis with bound oleic acid.
Journal of molecular biology 2007;369(5):1282-95.
2007: Jürgen U Linder; Sandra Bruder; Anita Schultz; Joachim E Schultz
Changes in purine specificity in tandem GAF chimeras from cyanobacterial cyaB1 adenylate cyclase and rat phosphodiesterase 2.
The FEBS journal 2007;274(6):1514-23.
2006: Dorothea Dittrich; Christine Keller; Stefan Ehlers; Joachim E Schultz; Peter Sander
Characterization of a Mycobacterium tuberculosis mutant deficient in pH-sensing adenylate cyclase Rv1264.
International journal of medical microbiology : IJMM 2006;296(8):563-6.
2006: Michael Hulko; Franziska Berndt; Markus Gruber; Jürgen U Linder; Vincent Truffault; Anita Schultz; Jörg Martin; Joachim E Schultz; Andrei N Lupas; Murray Coles
The HAMP domain structure implies helix rotation in transmembrane signaling.
Cell 2006;126(5):929-40.
2006: Amira Abdel Motaal; Ivo Tews; Joachim E Schultz; Jürgen U Linder
Fatty acid regulation of adenylyl cyclase Rv2212 from Mycobacterium tuberculosis H37Rv.
The FEBS journal 2006;273(18):4219-28.
2006: Thomas Zeuthen; Binghua Wu; Slavica Pavlovic-Djuranovic; Lars M Holm; Nestor L Uzcategui; Michael Duszenko; Jürgen Kun; Joachim E Schultz; Eric Beitz
Ammonia permeability of the aquaglyceroporins from Plasmodium falciparum, Toxoplasma gondii and Trypansoma brucei.
Molecular microbiology 2006;61(6):1598-608.
2006: Slavica Pavlovic-Djuranovic; Jürgen Kun; Joachim E Schultz; Eric Beitz
Dihydroxyacetone and methylglyoxal as permeants of the Plasmodium aquaglyceroporin inhibit parasite proliferation.
Biochimica et biophysica acta 2006;1758(8):1012-7.
2006: Sandra Bruder; Anita Schultz; Joachim E Schultz
Characterization of the tandem GAF domain of human phosphodiesterase 5 using a cyanobacterial adenylyl cyclase as a reporter enzyme.
The Journal of biological chemistry 2006;281(29):19969-76.
2006: Marco Gross-Langenhoff; Karina Hofbauer; Jost Weber; Anita Schultz; Joachim E Schultz
cAMP is a ligand for the tandem GAF domain of human phosphodiesterase 10 and cGMP for the tandem GAF domain of phosphodiesterase 11.
The Journal of biological chemistry 2006;281(5):2841-6.
2006: Eric Beitz; Binghua Wu; Lars M Holm; Joachim E Schultz; Thomas Zeuthen
Point mutations in the aromatic/arginine region in aquaporin 1 allow passage of urea, glycerol, ammonia, and protons.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(2):269-74.
2005: Ying Lan Guo; Ursula Kurz; Anita Schultz; Jürgen U Linder; Dorothea Dittrich; Christine Keller; Stefan Ehlers; Peter Sander; Joachim E Schultz
Interaction of Rv1625c, a mycobacterial class IIIa adenylyl cyclase, with a mammalian congener.
Molecular microbiology 2005;57(3):667-77.
2005: Lucila I Castro; Corinna Hermsen; Joachim E Schultz; Jürgen U Linder
Adenylyl cyclase Rv0386 from Mycobacterium tuberculosis H37Rv uses a novel mode for substrate selection.
The FEBS journal 2005;272(12):3085-92.
2005: Ivo Tews; Felix Findeisen; Irmgard Sinning; Anita Schultz; Joachim E Schultz; Jürgen U Linder
The structure of a pH-sensing mycobacterial adenylyl cyclase holoenzyme.
Science (New York, N.Y.) 2005;308(5724):1020-3.
2005: Andrew J Crossthwaite; Thomas Seebacher; Nanako Masada; Antonio Ciruela; Kim Dufraux; Joachim E Schultz; dermot cooper
The cytosolic domains of Ca2+-sensitive adenylyl cyclases dictate their targeting to plasma membrane lipid rafts.
The Journal of biological chemistry 2005;280(8):6380-91.
2005: Sangita C Sinha; Martina Wetterer; Stephen R Sprang; Joachim E Schultz; Jürgen U Linder
Origin of asymmetry in adenylyl cyclases: structures of Mycobacterium tuberculosis Rv1900c.
The EMBO journal 2005;24(4):663-73.
2005: Sergio E Martinez; Sandra Bruder; Anita Schultz; Ning Zheng; Joachim E Schultz; Joseph A Beavo; Jürgen U Linder
Crystal structure of the tandem GAF domains from a cyanobacterial adenylyl cyclase: modes of ligand binding and dimerization.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(8):3082-7.
2005: Sandra Bruder; Jürgen U Linder; Sergio E Martinez; Ning Zheng; Joseph A Beavo; Joachim E Schultz
The cyanobacterial tandem GAF domains from the cyaB2 adenylyl cyclase signal via both cAMP-binding sites.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(8):3088-92.
2004: Jürgen U Linder; Lucila I Castro; Ying-Lan Guo; Joachim E Schultz
Functional chimeras between the catalytic domains of the mycobacterial adenylyl cyclase Rv1625c and a Paramecium guanylyl cyclase.
FEBS letters 2004;568(1-3):151-4.
2004: Jürgen U Linder; Arne Hammer; Joachim E Schultz
The effect of HAMP domains on class IIIb adenylyl cyclases from Mycobacterium tuberculosis.
European journal of biochemistry / FEBS 2004;271(12):2446-51.
2004: Eric Beitz; Slavica Pavlovic-Djuranovic; Masato Yasui; Peter Agre; Joachim E Schultz
Molecular dissection of water and glycerol permeability of the aquaglyceroporin from Plasmodium falciparum by mutational analysis.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(5):1153-8.
2004: Jost H Weber; Andrey Vishnyakov; Kristina Hambach; Anita Schultz; Joachim E Schultz; Jürgen U Linder
Adenylyl cyclases from Plasmodium, Paramecium and Tetrahymena are novel ion channel/enzyme fusion proteins.
Cellular signalling 2004;16(1):115-25.
2003: Slavica Pavlovic-Djuranovic; Joachim E Schultz; Eric Beitz
A single aquaporin gene encodes a water/glycerol/urea facilitator in Toxoplasma gondii with similarity to plant tonoplast intrinsic proteins.
FEBS letters 2003;555(3):500-4.
2003: Jürgen U Linder; Joachim E Schultz
The class III adenylyl cyclases: multi-purpose signalling modules.
Cellular signalling 2003;15(12):1081-9.
2003: Eric Beitz; Hans-Peter Zenner; Joachim E Schultz
Aquaporin-mediated fluid regulation in the inner ear.
Cellular and molecular neurobiology 2003;23(3):315-29.
2002: Tobias Kanacher; Anita Schultz; Jürgen U Linder; Joachim E Schultz
A GAF-domain-regulated adenylyl cyclase from Anabaena is a self-activating cAMP switch.
The EMBO journal 2002;21(14):3672-80.
2002: Jürgen U Linder; Anita Schultz; Joachim E Schultz
Adenylyl cyclase Rv1264 from Mycobacterium tuberculosis has an autoinhibitory N-terminal domain.
The Journal of biological chemistry 2002;277(18):15271-6.
2002: Martin Hansen; Jürgen Kun; Joachim E Schultz; Eric Beitz
A single, bi-functional aquaglyceroporin in blood-stage Plasmodium falciparum malaria parasites.
The Journal of biological chemistry 2002;277(7):4874-82.
2002: Jürgen U Linder; Joachim E Schultz
Guanylyl cyclases in unicellular organisms.
Molecular and cellular biochemistry 2002;230(1-2):149-58.
2001: Ying-Lan Guo; Thomas Seebacher; Ursula Kurz; Jürgen U Linder; Joachim E Schultz
Adenylyl cyclase Rv1625c of Mycobacterium tuberculosis: a progenitor of mammalian adenylyl cyclases.
The EMBO journal 2001;20(14):3667-75.
2001: Philippe Dessen; Marek Zagulski; Robert Gromadka; Helmut Plattner; Roland Kissmehl; E Meyer; M Bétermier; Joachim E Schultz; Jürgen U Linder; R E Pearlman; Ching Kung; J Forney; Birgit H Satir; Judith L Van Houten; Anne-Marie Keller; Marine Froissard; Linda Sperling; Jean Cohen
Paramecium genome survey: a pilot project.
Trends in genetics : TIG 2001;17(6):306-8.
2001: Thomas Seebacher; Jürgen U Linder; Joachim E Schultz
An isoform-specific interaction of the membrane anchors affects mammalian adenylyl cyclase type V activity.
European journal of biochemistry / FEBS 2001;268(1):105-10.
2000: Jürgen U Linder; T Hoffmann; Ursula Kurz; Joachim E Schultz
A guanylyl cyclase from Paramecium with 22 transmembrane spans. Expression of the catalytic domains and formation of chimeras with the catalytic domains of mammalian adenylyl cyclases.
The Journal of biological chemistry 2000;275(15):11235-40.
2000: Ying-Lan Guo; Ursula Kurz; Joachim E Schultz; C C Lim; Bernd Wiederanders; Klaus Schilling
The alpha1/2 helical backbone of the prodomains defines the intrinsic inhibitory specificity in the cathepsin L-like cysteine protease subfamily.
FEBS letters 2000;469(2-3):203-7.
1999: Jürgen U Linder; P Engel; A Reimer; T Krüger; Helmut Plattner; Anita Schultz; Joachim E Schultz
Guanylyl cyclases with the topology of mammalian adenylyl cyclases and an N-terminal P-type ATPase-like domain in Paramecium, Tetrahymena and Plasmodium.
The EMBO journal 1999;18(15):4222-32.
1999: Eric Beitz; Hidetaka Kumagami; Peter Krippeit-Drews; J Peter Ruppersberg; Joachim E Schultz
Expression pattern of aquaporin water channels in the inner ear of the rat. The molecular basis for a water regulation system in the endolymphatic sac.
Hearing research 1999;132(1-2):76-84.
1999: Hidetaka Kumagami; Eric Beitz; Karen Wild; Hans-Peter Zenner; J Peter Ruppersberg; Joachim E Schultz
Expression pattern of adenylyl cyclase isoforms in the inner ear of the rat by RT-PCR and immunochemical localization of calcineurin in the organ of Corti.
Hearing research 1999;132(1-2):69-75.
1999: Eric Beitz; Joachim E Schultz
The mammalian aquaporin water channel family: A promising new drug target.
Current medicinal chemistry 1999;6(6):457-67.
1999: Eric Beitz; Joachim E Schultz
[Aquaporin--a cellular water channel as a therapeutic target?].
Pharmazie in unserer Zeit 1999;28(2):67-73.
1999: Thomas Seebacher; Eric Beitz; Hidetaka Kumagami; Karen Wild; J Peter Ruppersberg; Joachim E Schultz
Expression of membrane-bound and cytosolic guanylyl cyclases in the rat inner ear.
Hearing research 1999;127(1-2):95-102.
1998: Kirsten Grothe; C Hanke; Massoud Momayezi; Roland Kissmehl; Helmut Plattner; Joachim E Schultz
Functional characterization and localization of protein phosphatase type 2C from Paramecium.
The Journal of biological chemistry 1998;273(30):19167-72.
1998: Eric Beitz; H Völkel; Y Guo; Joachim E Schultz
Adenylyl cyclase type 7 is the predominant isoform in the bovine retinal pigment epithelium.
Acta anatomica 1998;162(2-3):157-62.
1997: Gunter Maubach; Klaus Schilling; W Rommerskirch; Ingrid Wenz; Joachim E Schultz; Ekkehard Weber; Bernd Wiederanders
The inhibition of cathepsin S by its propeptide--specificity and mechanism of action.
European journal of biochemistry / FEBS 1997;250(3):745-50.
1997: Karin Hauser; Roland Kissmehl; J Linder; Joachim E Schultz; F Lottspeich; Helmut Plattner
Identification of isoforms of the exocytosis-sensitive phosphoprotein PP63/parafusin in Paramecium tetraurelia and demonstration of phosphoglucomutase activity.
The Biochemical journal 1997;323 ( Pt 1)():289-96.
1997: Joachim E Schultz; Y Guo; G Kleefeld; H Völkel
Hyperpolarization- and depolarization-activated Ca2+ currents in Paramecium trigger behavioral changes and cGMP formation independently.
The Journal of membrane biology 1997;156(3):251-9.
1996: Massoud Momayezi; D Wloga; Roland Kissmehl; Helmut Plattner; G Jung; S Klumpp; Joachim E Schultz
Immunolocalization of protein phosphatase type 1 in Paramecium cells using antibodies against recombinant protein and peptides.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1996;44(8):891-905.
1996: H Völkel; U Kurz; J Linder; S Klumpp; V Gnau; G Jung; Joachim E Schultz
Cathepsin L is an intracellular and extracellular protease in Paramecium tetraurelia. Purification, cloning, sequencing and specific inhibition by its expressed propeptide.
European journal of biochemistry / FEBS 1996;238(1):198-206.
1996: H Völkel; Eric Beitz; S Klumpp; Joachim E Schultz
Cloning and expression of a bovine adenylyl cyclase type VII specific to the retinal pigment epithelium.
FEBS letters 1996;378(3):245-9.
1994: S Klumpp; C Hanke; A Donella-Deana; A Beyer; R Kellner; L A Pinna; Joachim E Schultz
A membrane-bound protein phosphatase type 2C from Paramecium tetraurelia. Purification, characterization, and cloning.
The Journal of biological chemistry 1994;269(52):32774-80.
1994: Joachim E Schultz; C Schönborn
Cyclic AMP formation in Tetrahymena pyriformis is controlled by a K(+)-conductance.
FEBS letters 1994;356(2-3):322-6.
1994: Joachim E Schultz; S Klumpp
Cyclic GMP in lower forms.
Advances in pharmacology (San Diego, Calif.) 1994;26():285-303.
1993: Joachim E Schultz; S Klumpp
Cyclic nucleotides and calcium signaling in Paramecium.
Advances in second messenger and phosphoprotein research 1993;27():25-46.
1992: G Friderich; S Klumpp; C B Russell; R D Hinrichsen; R Kellner; Joachim E Schultz
Purification, characterization and structure of protein phosphatase 1 from the cilia of Paramecium tetraurelia.
European journal of biochemistry / FEBS 1992;209(1):43-9.
1992: W D Freund; G W Mayr; C Tietz; Joachim E Schultz
Metabolism of inositol phosphates in the protozoan Paramecium. Characterization of a novel inositol-hexakisphosphate-dephosphorylating enzyme.
European journal of biochemistry / FEBS 1992;207(1):359-67.
1992: Joachim E Schultz; S Klumpp; R Benz; W J Schürhoff-Goeters; A Schmid
Regulation of adenylyl cyclase from Paramecium by an intrinsic potassium conductance.
Science (New York, N.Y.) 1992;255(5044):600-3.
1991: S Klumpp; Joachim E Schultz
Identification of a 42 kDa protein as a substrate of protein phosphatase 1 in cilia from Paramecium.
FEBS letters 1991;288(1-2):60-4.
1990: S Klumpp; P Cohen; Joachim E Schultz
Chromatographic separation of four Ser/Thr-protein phosphatases from solubilized ciliary membranes of Paramecium tetraurelia by heparin-sepharose.
Journal of chromatography 1990;521(2):179-86.
1990: S Steinlen; S Klumpp; Joachim E Schultz
Guanylate cyclase in olfactory cilia from rat and pig.
Biochimica et biophysica acta 1990;1054(1):69-72.
1990: S Klumpp; P Cohen; Joachim E Schultz
Okadaic acid, an inhibitor of protein phosphatase 1 in Paramecium, causes sustained Ca2(+)-dependent backward swimming in response to depolarizing stimuli.
The EMBO journal 1990;9(3):685-9.
1990: S Klumpp; Joachim E Schultz
Alkaline phosphatase from Paramecium cilia and cell bodies: purification and characterization.
Biochimica et biophysica acta 1990;1037(2):233-9.
1988: R D Hinrichsen; Joachim E Schultz
Paramecium: a model system for the study of excitable cells.
Trends in neurosciences 1988;11(1):27-32.
1987: Joachim E Schultz; D G Uhl; S Klumpp
Ionic regulation of adenylate cyclase from the cilia of Paramecium tetraurelia.
The Biochemical journal 1987;246(1):187-92.
1987: Joachim E Schultz; B H Schmidt
Treatment of rats with thyrotropin (TSH) reduces the adrenoceptor sensitivity of adenylate cyclase from cerebral cortex.
Neurochemistry international 1987;10(2):173-8.
1983: S Klumpp; G Kleefeld; Joachim E Schultz
Calcium/calmodulin-regulated guanylate cyclase of the excitable ciliary membrane from Paramecium. Dissociation of calmodulin by La3+: calmodulin specificity and properties of the reconstituted guanylate cyclase.
The Journal of biological chemistry 1983;258(20):12455-9.
1983: C Kopanski; M Türck; Joachim E Schultz
Effects of long-term treatment of rats with antidepressants on adrenergic-receptor sensitivity in cerebral cortex: Structure activity study.
Neurochemistry international 1983;5(5):649-59.