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Lori Schultz

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M-H Lee; S-R Lin; J-Y Chang; Lori Schultz; J Heath; Li-Jin Hsu; Y-M Kuo; Qunying Hong; M-F Chiang; C-X Gong; C-I Sze; N-S Chang
TGF-β induces TIAF1 self-aggregation via type II receptor-independent signaling that leads to generation of amyloid β plaques in Alzheimer's disease.
Qunying Hong; Chun-I Sze; Sing-Ru Lin; Ming-Hui Lee; Ruei-Yu He; Lori Schultz; Jean-Yun Chang; Shean-Jen Chen; Robert J Boackle; Li-Jin Hsu; Nan-Shan Chang
Complement C1q activates tumor suppressor WWOX to induce apoptosis in prostate cancer cells.
Li-Jin Hsu; Qunying Hong; Lori Schultz; Emory Kuo; Sing-Ru Lin; Ming-Hui Lee; Yee-Shin Lin; Nan-Shan Chang
Zfra is an inhibitor of Bcl-2 expression and cytochrome c release from the mitochondria.

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All Publications

2010: M-H Lee; S-R Lin; J-Y Chang; Lori Schultz; J Heath; Li-Jin Hsu; Y-M Kuo; Qunying Hong; M-F Chiang; C-X Gong; C-I Sze; N-S Chang
TGF-β induces TIAF1 self-aggregation via type II receptor-independent signaling that leads to generation of amyloid β plaques in Alzheimer's disease.
Cell death & disease 2010;1():e110.
2009: Qunying Hong; Chun-I Sze; Sing-Ru Lin; Ming-Hui Lee; Ruei-Yu He; Lori Schultz; Jean-Yun Chang; Shean-Jen Chen; Robert J Boackle; Li-Jin Hsu; Nan-Shan Chang
Complement C1q activates tumor suppressor WWOX to induce apoptosis in prostate cancer cells.
PloS one 2009;4(6):e5755.
2008: Li-Jin Hsu; Qunying Hong; Lori Schultz; Emory Kuo; Sing-Ru Lin; Ming-Hui Lee; Yee-Shin Lin; Nan-Shan Chang
Zfra is an inhibitor of Bcl-2 expression and cytochrome c release from the mitochondria.
Cellular signalling 2008;20(7):1303-12.
2007: Qunying Hong; Li-Jin Hsu; Lori Schultz; Nicole Pratt; Jeffrey Mattison; Nan-Shan Chang
Zfra affects TNF-mediated cell death by interacting with death domain protein TRADD and negatively regulates the activation of NF-kappaB, JNK1, p53 and WOX1 during stress response.
BMC molecular biology 2007;8():50.
2007: Qunying Hong; Emory Kuo; Lori Schultz; Robert J Boackle; Nan-Shan Chang
Conformationally altered hyaluronan restricts complement classical pathway activation by binding to C1q, C1r, C1s, C2, C5 and C9, and suppresses WOX1 expression in prostate DU145 cells.
International journal of molecular medicine 2007;19(1):173-9.
2005: Nan-Shan Chang; Joan Doherty; Amy Ensign; Lori Schultz; Li-Jin Hsu; Qunying Hong
WOX1 is essential for tumor necrosis factor-, UV light-, staurosporine-, and p53-mediated cell death, and its tyrosine 33-phosphorylated form binds and stabilizes serine 46-phosphorylated p53.
The Journal of biological chemistry 2005;280(52):43100-8.
2005: Li-Jin Hsu; Lori Schultz; Jeffrey Mattison; Yee-Shin Lin; Nan-Shan Chang
Cloning and characterization of a small-size peptide Zfra that regulates the cytotoxic function of tumor necrosis factor by interacting with JNK1.
Biochemical and biophysical research communications 2005;327(2):415-23.
2005: Nan-Shan Chang; Lori Schultz; Li-Jin Hsu; Jennifer Lewis; Meng Su; Chun-I Sze
17beta-Estradiol upregulates and activates WOX1/WWOXv1 and WOX2/WWOXv2 in vitro: potential role in cancerous progression of breast and prostate to a premetastatic state in vivo.
Oncogene 2005;24(4):714-23.
2004: Chun-I Sze; Meng Su; Subbiah Pugazhenthi; Purevsuren Jambal; Li-Jin Hsu; John Heath; Lori Schultz; Nan-Shan Chang
Down-regulation of WW domain-containing oxidoreductase induces Tau phosphorylation in vitro. A potential role in Alzheimer's disease.
The Journal of biological chemistry 2004;279(29):30498-506.
2004: Lori Schultz; Smaira Khera; Daniel Sleve; John Heath; Nan-Shan Chang
TIAF1 and p53 functionally interact in mediating apoptosis and silencing of TIAF1 abolishes nuclear translocation of serine 15-phosphorylated p53.
DNA and cell biology 2004;23(1):67-74.
2003: Nan-Shan Chang; Joan Doherty; Amy Ensign; Jennifer Lewis; John Heath; Lori Schultz; Shur-Tzu Chen; Udo Oppermann
Molecular mechanisms underlying WOX1 activation during apoptotic and stress responses.
Biochemical pharmacology 2003;66(8):1347-54.
2001: Nan-Shan Chang; Nicole Pratt; John Heath; Lori Schultz; D Sleve; Gregory Carey; N Zevotek
Hyaluronidase induction of a WW domain-containing oxidoreductase that enhances tumor necrosis factor cytotoxicity.
The Journal of biological chemistry 2001;276(5):3361-70.
2000: Nan-Shan Chang; Lori Schultz; John Heath
Suppression of IkappaBalpha expression is necessary for c-Jun N-terminal kinase-mediated enhancement of Fas cytotoxicity.
Biochemical and biophysical research communications 2000;274(1):4-10.