FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Maria Schumacher

Research Profile

Concepts & Ideas

Procedures

X Ray Crystallography

Chemicals & Drugs

Phenomena

Genes & Molecular Sequences

Amino Acid Sequences

Living Beings

Co-author Network

Publications

TOP 3
Lisheng Ni; Nagababu Chinnam; Nam K Tonthat; Maria A Schumacher
Structures of the Escherichia coli transcription activator and regulator of diauxie, XylR: an AraC DNA-binding family member with a LacI/GalR ligand-binding domain.
Maria A Schumacher; Mareen Sprehe; Maike Bartholomae; Wolfgang Hillen; Richard G Brennan
Structures of carbon catabolite protein A-(HPr-Ser46-P) bound to diverse catabolite response element sites reveal the basis for high-affinity binding to degenerate DNA operators.
Nam Ky Tonthat; Stefan T Arold; Brian F Pickering; Michael W Van Dyke; Shoudan Liang; Yue Lu; Tushar K Beuria; William Margolin; Maria A Schumacher
Molecular mechanism by which the nucleoid occlusion factor, SlmA, keeps cytokinesis in check.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Maria Schumacher (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Lisheng Ni; Nagababu Chinnam; Nam K Tonthat; Maria A Schumacher
Structures of the Escherichia coli transcription activator and regulator of diauxie, XylR: an AraC DNA-binding family member with a LacI/GalR ligand-binding domain.
Nucleic acids research 2013;41(3):1998-2008.
2011: Maria A Schumacher; Mareen Sprehe; Maike Bartholomae; Wolfgang Hillen; Richard G Brennan
Structures of carbon catabolite protein A-(HPr-Ser46-P) bound to diverse catabolite response element sites reveal the basis for high-affinity binding to degenerate DNA operators.
Nucleic acids research 2011;39(7):2931-42.
2011: Nam Ky Tonthat; Stefan T Arold; Brian F Pickering; Michael W Van Dyke; Shoudan Liang; Yue Lu; Tushar K Beuria; William Margolin; Maria A Schumacher
Molecular mechanism by which the nucleoid occlusion factor, SlmA, keeps cytokinesis in check.
The EMBO journal 2011;30(1):154-64.
2011: Kate M Peters; Benjamin E Brooks; Maria A Schumacher; Ronald A Skurray; Richard G Brennan; Melissa H Brown
A single acidic residue can guide binding site selection but does not govern QacR cationic-drug affinity.
PloS one 2011;6(1):e15974.
2010: Maria A Schumacher; Kevin M Piro; Weijun Xu
Insight into F plasmid DNA segregation revealed by structures of SopB and SopB-DNA complexes.
Nucleic acids research 2010;38(13):4514-26.
2010: Lisheng Ni; Weijun Xu; Muthiah Kumaraswami; Maria A Schumacher
Plasmid protein TubR uses a distinct mode of HTH-DNA binding and recruits the prokaryotic tubulin homolog TubZ to effect DNA partition.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(26):11763-8.
2010: Mareen Sprehe; John C Fisk; Sarah M McEvoy; Laurie K Read; Maria A Schumacher
Structure of the Trypanosoma brucei p22 protein, a cytochrome oxidase subunit II-specific RNA-editing accessory factor.
The Journal of biological chemistry 2010;285(24):18899-908.
2009: Lisheng Ni; Slade O Jensen; Nam Ky Tonthat; Tracey Berg; Stephen M Kwong; Fiona H X Guan; Melissa H Brown; Ronald A Skurray; Neville Firth; Maria A Schumacher
The Staphylococcus aureus pSK41 plasmid-encoded ArtA protein is a master regulator of plasmid transmission genes and contains a RHH motif used in alternate DNA-binding modes.
Nucleic acids research 2009;37(20):6970-83.
2009: Thomas D Dunham; Weijun Xu; Barbara E Funnell; Maria A Schumacher
Structural basis for ADP-mediated transcriptional regulation by P1 and P7 ParA.
The EMBO journal 2009;28(12):1792-802.
2009: Maria A Schumacher; Kevin M Piro; Weijun Xu; Sonja Hansen; Kim Lewis; Richard G Brennan
Molecular mechanisms of HipA-mediated multidrug tolerance and its neutralization by HipB.
Science (New York, N.Y.) 2009;323(5912):396-401.
2008: Sergei Boudko; Jürgen Engel; Kenji Okuyama; Kazunori Mizuno; Hans Peter Bächinger; Maria A Schumacher
Crystal structure of human type III collagen Gly991-Gly1032 cystine knot-containing peptide shows both 7/2 and 10/3 triple helical symmetries.
The Journal of biological chemistry 2008;283(47):32580-9.
2008: Kate M Peters; Jason T Schuman; Ronald A Skurray; Marion H Brown; Richard G Brennan; Maria A Schumacher
QacR-cation recognition is mediated by a redundancy of residues capable of charge neutralization.
Biochemistry 2008;47(31):8122-9.
2008: Alena Zíková; Jana Kopecná; Maria A Schumacher; Kenneth Stuart; Lukás Trantírek; Julius Lukes
Structure and function of the native and recombinant mitochondrial MRP1/MRP2 complex from Trypanosoma brucei.
International journal for parasitology 2008;38(8-9):901-12.
2008: Maria A Schumacher
Structural biology of plasmid partition: uncovering the molecular mechanisms of DNA segregation.
The Biochemical journal 2008;412(1):1-18.
2008: Deepti Srinivas Wilkinson; Wen-Wei Tsai; Maria A Schumacher; Michelle Craig Barton
Chromatin-bound p53 anchors activated Smads and the mSin3A corepressor to confer transforming-growth-factor-beta-mediated transcription repression.
Molecular and cellular biology 2008;28(6):1988-98.
2007: Maria A Schumacher; Tiffany C Glover; Anthony J Brzoska; Slade O Jensen; Thomas D Dunham; Ronald A Skurray; Neville Firth
Segrosome structure revealed by a complex of ParR with centromere DNA.
Nature 2007;450(7173):1268-71.
2007: Isabelle Andres-Enguix; Alex Caley; Raquel Yustos; Maria A Schumacher; Pietro D Spanu; Robert Dickinson; Mervyn Maze; Nicholas P Franks
Determinants of the anesthetic sensitivity of two-pore domain acid-sensitive potassium channels: molecular cloning of an anesthetic-activated potassium channel from Lymnaea stagnalis.
The Journal of biological chemistry 2007;282(29):20977-90.
2007: Maria A Schumacher; Gerald Seidel; Wolfgang Hillen; Richard G Brennan
Structural mechanism for the fine-tuning of CcpA function by the small molecule effectors glucose 6-phosphate and fructose 1,6-bisphosphate.
Journal of molecular biology 2007;368(4):1042-50.
2007: Anthony G Vecchiarelli; Maria A Schumacher; Barbara E Funnell
P1 partition complex assembly involves several modes of protein-DNA recognition.
The Journal of biological chemistry 2007;282(15):10944-52.
2007: Maria A Schumacher; André Mansoor; Barbara E Funnell
Structure of a four-way bridged ParB-DNA complex provides insight into P1 segrosome assembly.
The Journal of biological chemistry 2007;282(14):10456-64.
2007: Maria A Schumacher
Structural biology of plasmid segregation proteins.
Current opinion in structural biology 2007;17(1):103-9.
2006: Maria A Schumacher; Kazunori Mizuno; Hans Peter Bächinger
The crystal structure of a collagen-like polypeptide with 3(S)-hydroxyproline residues in the Xaa position forms a standard 7/2 collagen triple helix.
The Journal of biological chemistry 2006;281(37):27566-74.
2006: Maria A Schumacher; Elham Karamooz; Alena Zíková; Lukás Trantírek; Julius Lukes
Crystal structures of T. brucei MRP1/MRP2 guide-RNA binding complex reveal RNA matchmaking mechanism.
Cell 2006;126(4):701-11.
2006: Maria A Schumacher; Gerald Seidel; Wolfgang Hillen; Richard G Brennan
Phosphoprotein Crh-Ser46-P displays altered binding to CcpA to effect carbon catabolite regulation.
The Journal of biological chemistry 2006;281(10):6793-800.
2005: Maria A Schumacher; Barbara E Funnell
Structures of ParB bound to DNA reveal mechanism of partition complex formation.
Nature 2005;438(7067):516-9.
2005: Maria A Schumacher; Kazunori Mizuno; Hans Peter Bächinger
The crystal structure of the collagen-like polypeptide (glycyl-4(R)-hydroxyprolyl-4(R)-hydroxyprolyl)9 at 1.55 A resolution shows up-puckering of the proline ring in the Xaa position.
The Journal of biological chemistry 2005;280(21):20397-403.
2004: Maria A Schumacher; Gregory S Allen; Marco Diel; Gerald Seidel; Wolfgang Hillen; Richard G Brennan
Structural basis for allosteric control of the transcription regulator CcpA by the phosphoprotein HPr-Ser46-P.
Cell 2004;118(6):731-41.
2004: Maria A Schumacher; Marshall C Miller; Richard G Brennan
Structural mechanism of the simultaneous binding of two drugs to a multidrug-binding protein.
The EMBO journal 2004;23(15):2923-30.
2004: Maria A Schumacher; Matthew Crum; Marshall C Miller
Crystal structures of apocalmodulin and an apocalmodulin/SK potassium channel gating domain complex.
Structure (London, England : 1993) 2004;12(5):849-60.
2004: David S Murray; Maria A Schumacher; Richard G Brennan
Crystal structures of QacR-diamidine complexes reveal additional multidrug-binding modes and a novel mechanism of drug charge neutralization.
The Journal of biological chemistry 2004;279(14):14365-71.
2003: Maria A Schumacher; Audrey O T Lau; Patricia J Johnson
Structural basis of core promoter recognition in a primitive eukaryote.
Cell 2003;115(4):413-24.
2003: Maria A Schumacher; Richard G Brennan
Deciphering the molecular basis of multidrug recognition: crystal structures of the Staphylococcus aureus multidrug binding transcription regulator QacR.
Research in microbiology 2003;154(2):69-77.
2002: Maria A Schumacher; Richard G Brennan
Structural mechanisms of multidrug recognition and regulation by bacterial multidrug transcription factors.
Molecular microbiology 2002;45(4):885-93.
2002: Andrew Bruening-Wright; Maria A Schumacher; John P Adelman; James Maylie
Localization of the activation gate for small conductance Ca2+-activated K+ channels.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(15):6499-506.
2002: Maria A Schumacher; Robert F Pearson; Thorleif Møller; Poul Valentin-Hansen; Richard G Brennan
Structures of the pleiotropic translational regulator Hfq and an Hfq-RNA complex: a bacterial Sm-like protein.
The EMBO journal 2002;21(13):3546-56.
2002: Maria A Schumacher; John P Adelman
Ion channels: an open and shut case.
Nature 2002;417(6888):501-2.
2002: Maria A Schumacher; Jacob L Todd; Adrian E Rice; Kirk G Tanner; John M Denu
Structural basis for the recognition of a bisphosphorylated MAP kinase peptide by human VHR protein Phosphatase.
Biochemistry 2002;41(9):3009-17.
2002: Maria A Schumacher; Marshall C Miller; Steve Grkovic; Marion H Brown; Ronald A Skurray; Richard G Brennan
Structural basis for cooperative DNA binding by two dimers of the multidrug-binding protein QacR.
The EMBO journal 2002;21(5):1210-8.
2002: Maria A Schumacher; Caleb J Bashor; Minsun Hong Song; Kanao Otsu; Shuren Zhu; Ronald J Parry; Buddy Ullman; Richard G Brennan
The structural mechanism of GTP stabilized oligomerization and catalytic activation of the Toxoplasma gondii uracil phosphoribosyltransferase.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(1):78-83.
2001: Maria A Schumacher; Marshall C Miller; Steve Grkovic; Marion H Brown; Ronald A Skurray; Richard G Brennan
Structural mechanisms of QacR induction and multidrug recognition.
Science (New York, N.Y.) 2001;294(5549):2158-63.
2001: Steve Grkovic; Marion H Brown; Maria A Schumacher; Richard G Brennan; Ronald A Skurray
The staphylococcal QacR multidrug regulator binds a correctly spaced operator as a pair of dimers.
Journal of bacteriology 2001;183(24):7102-9.
2001: Maria A Schumacher; Andre F Rivard; Hans Peter Bächinger; John P Adelman
Structure of the gating domain of a Ca2+-activated K+ channel complexed with Ca2+/calmodulin.
Nature 2001;410(6832):1120-4.
2001: J C Craig; Maria A Schumacher; Steven E Mansoor; David L Farrens; Richard G Brennan; Richard H Goodman
Consensus and variant cAMP-regulated enhancers have distinct CREB-binding properties.
The Journal of biological chemistry 2001;276(15):11719-28.
2001: Maria A Schumacher; Barry K Hurlburt; Richard G Brennan
Crystal structures of SarA, a pleiotropic regulator of virulence genes in S. aureus.
Nature 2001;409(6817):215-9.
2000: Maria A Schumacher; Richard H Goodman; Richard G Brennan
The structure of a CREB bZIP.somatostatin CRE complex reveals the basis for selective dimerization and divalent cation-enhanced DNA binding.
The Journal of biological chemistry 2000;275(45):35242-7.
2000: McKay Brown; Maria A Schumacher; gregory wiens; Richard G Brennan; Marvin B Rittenberg
The structural basis of repertoire shift in an immune response to phosphocholine.
The Journal of experimental medicine 2000;191(12):2101-12.
2000: Maria A Schumacher; DM Scott; I I Mathews; S E Ealick; DS Roos; Buddy Ullman; Richard G Brennan
Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding.
Journal of molecular biology 2000;298(5):875-93.
2000: Maria A Schumacher; DM Scott; I I Mathews; S E Ealick; DS Roos; Buddy Ullman; Richard G Brennan
Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding.
Journal of molecular biology 2000;296(2):549-67.
1999: Arthur Glasfeld; A N Koehler; Maria A Schumacher; Richard G Brennan
The role of lysine 55 in determining the specificity of the purine repressor for its operators through minor groove interactions.
Journal of molecular biology 1999;291(2):347-61.
1999: TM Rechtin; Allison F Gillaspy; Maria A Schumacher; Richard G Brennan; Mark S Smeltzer; Barry K Hurlburt
Characterization of the SarA virulence gene regulator of Staphylococcus aureus.
Molecular microbiology 1999;33(2):307-16.
1998: Maria A Schumacher; Darrick Carter; DM Scott; DS Roos; Buddy Ullman; Richard G Brennan
Crystal structures of Toxoplasma gondii uracil phosphoribosyltransferase reveal the atomic basis of pyrimidine discrimination and prodrug binding.
The EMBO journal 1998;17(12):3219-32.
1998: F Lu; Maria A Schumacher; Dennis N Arvidson; Andreas Haldimann; Barry L Wanner; Howard Zalkin; Richard G Brennan
Structure-based redesign of corepressor specificity of the Escherichia coli purine repressor by substitution of residue 190.
Biochemistry 1998;37(4):971-82.
1997: Maria A Schumacher; Arthur Glasfeld; Howard Zalkin; Richard G Brennan
The X-ray structure of the PurR-guanine-purF operator complex reveals the contributions of complementary electrostatic surfaces and a water-mediated hydrogen bond to corepressor specificity and binding affinity.
The Journal of biological chemistry 1997;272(36):22648-53.
1997: Maria A Schumacher; EE Zheleznova; K S Poundstone; R Kluger; Richard T Jones; Richard G Brennan
Allosteric intermediates indicate R2 is the liganded hemoglobin end state.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(15):7841-4.
1996: Maria A Schumacher; Darrick Carter; Buddy Ullman; D S Roos; Richard G Brennan
Crystal structures of Toxoplasma gondii HGXPRTase reveal the catalytic role of a long flexible loop.
Nature structural biology 1996;3(10):881-7.
1996: Mitchell Lewis; Geoffrey A. Chang; N C Horton; M A Kercher; H C Pace; Maria A Schumacher; Richard G Brennan; Ponzy Lu
Crystal structure of the lactose operon repressor and its complexes with DNA and inducer.
Science (New York, N.Y.) 1996;271(5253):1247-54.
1995: Aritaka Nagadoi; S Morikawa; H Nakamura; M Enari; K Kobayashi; H Yamamoto; G Sampei; K Mizobuchi; Maria A Schumacher; Richard G Brennan
Structural comparison of the free and DNA-bound forms of the purine repressor DNA-binding domain.
Structure (London, England : 1993) 1995;3(11):1217-24.
1995: Maria A Schumacher; Kang-Yell Choi; F Lu; H Zalkin; Richard G Brennan
Mechanism of corepressor-mediated specific DNA binding by the purine repressor.
Cell 1995;83(1):147-55.
1995: Maria A Schumacher; M M Dixon; Ronald Kluger; Richard T Jones; Richard G Brennan
Allosteric transition intermediates modelled by crosslinked haemoglobins.
Nature 1995;375(6526):84-7.
1995: Aritaka Nagadoi; K Nakazawa; S Morikawa; H Nakamura; G Sampei; K Mizobuchi; H Yamamoto; Maria A Schumacher; Richard G Brennan; Yoshifumi Nishimura
Conformational changes of purine repressor DNA-binding domain upon complexation with DNA.
Nucleic acids symposium series 1995;(34):63-4.
1994: Maria A Schumacher; Kang-Yell Choi; H Zalkin; Richard G Brennan
Crystal structure of LacI member, PurR, bound to DNA: minor groove binding by alpha helices.
Science (New York, N.Y.) 1994;266(5186):763-70.
1994: Maria A Schumacher; Kang-Yell Choi; H Zalkin; Richard G Brennan
Crystallization and preliminary X-ray analysis of an Escherichia coli purine repressor-hypoxanthine-DNA complex.
Journal of molecular biology 1994;242(3):302-5.
1993: Maria A Schumacher; J R Macdonald; J Björkman; S L Mowbray; Richard G Brennan
Structural analysis of the purine repressor, an Escherichia coli DNA-binding protein.
The Journal of biological chemistry 1993;268(17):12282-8.
1992: Maria A Schumacher; Kang-Yell Choi; H Zalkin; Richard G Brennan
Crystallization and preliminary X-ray studies on the co-repressor binding domain of the Escherichia coli purine repressor.
Journal of molecular biology 1992;225(4):1131-3.