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Stéphane Schurmans

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Valérie Pouillon; Christophe Erneux; Christophe Frippiat; Yoann Maréchal; Stéphane Schurmans
Inositol 1,4,5-trisphosphate 3-kinase B (Itpkb) controls survival, proliferation and cytokine production in mouse peripheral T cells.
Eléonore Dubois; Christophe Erneux; Lazaros C Foukas; Jean-Claude Henquin; Monique Jacoby; Eileen Pernot; Serge N Schiffmann; Marianne Blockmans; Bart Vanhaesebroeck; Stéphane Schurmans
Developmental defects and rescue from glucose intolerance of a catalytically-inactive novel Ship2 mutant mouse.
Eileen Pernot; Valérie Pouillon; Bernard C Rossier; Sara Terryn; Renaud Beauwens; Marianne Blockmans; Siew Chiat Cheong; Olivier Devuyst; Christophe Erneux; Stéphanie Gayral; Monique Jacoby; Sylvie Janas; Nicolas Markadieu; Stéphane Schurmans
The inositol Inpp5k 5-phosphatase affects osmoregulation through the vasopressin-aquaporin 2 pathway in the collecting system.

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All Publications

2013: Valérie Pouillon; Christophe Erneux; Christophe Frippiat; Yoann Maréchal; Stéphane Schurmans
Inositol 1,4,5-trisphosphate 3-kinase B (Itpkb) controls survival, proliferation and cytokine production in mouse peripheral T cells.
Advances in biological regulation 2013;53(1):39-50.
2012: Eléonore Dubois; Christophe Erneux; Lazaros C Foukas; Jean-Claude Henquin; Monique Jacoby; Eileen Pernot; Serge N Schiffmann; Marianne Blockmans; Bart Vanhaesebroeck; Stéphane Schurmans
Developmental defects and rescue from glucose intolerance of a catalytically-inactive novel Ship2 mutant mouse.
Cellular signalling 2012;24(11):1971-80.
2011: Eileen Pernot; Valérie Pouillon; Bernard C Rossier; Sara Terryn; Renaud Beauwens; Marianne Blockmans; Siew Chiat Cheong; Olivier Devuyst; Christophe Erneux; Stéphanie Gayral; Monique Jacoby; Sylvie Janas; Nicolas Markadieu; Stéphane Schurmans
The inositol Inpp5k 5-phosphatase affects osmoregulation through the vasopressin-aquaporin 2 pathway in the collecting system.
Pflügers Archiv : European journal of physiology 2011;462(6):871-83.
2011: Evrard Nguidjoe; Nathalie Pachera; Jacques Rahier; Stéphane Schurmans; Abdullah Sener; Sophie Sokolow; Jean-Marie Vanderwinden; Florent Allagnat; Serge Bigabwa; Alessandra K Cardozo; Eva D'Amico; Marianne Depreter; Décio L Eizirik; Geraldine Joanny; Mario Manto; Jan Mast; Eduard Montanya; André Herchuelz
Heterozygous inactivation of the Na/Ca exchanger increases glucose-induced insulin release, β-cell proliferation, and mass.
Diabetes 2011;60(8):2076-85.
2011: Stéphane Schurmans; Valérie Pouillon; Yoann Maréchal
Regulation of B cell survival, development and function by inositol 1,4,5-trisphosphate 3-kinase B (Itpkb).
Advances in enzyme regulation 2011;51(1):66-73.
2011: Yoann Maréchal; Séverine Quéant; Selena Polizzi; Valérie Pouillon; Stéphane Schurmans
Inositol 1,4,5-trisphosphate 3-kinase B controls survival and prevents anergy in B cells.
Immunobiology 2011;216(1-2):103-9.
2010: Delphine Baup; Laurent Fraga; Eileen Pernot; Annette van Acker; Anne-Sophie Vanherck; Karine Breckpot; Kris Thielemans; Stéphane Schurmans; Muriel Moser; Oberdan Leo
Variegation and silencing in a lentiviral-based murine transgenic model.
Transgenic research 2010;19(3):399-414.
2008: Yonghui Jia; Stéphane Schurmans; Hongbo R Luo
Regulation of innate immunity by inositol 1,3,4,5-tetrakisphosphate.
Cell cycle (Georgetown, Tex.) 2008;7(18):2803-8.
2008: Graham J Jeffs; Bruno P Meloni; Sophie Sokolow; Andre Herchuelz; Stéphane Schurmans; Neville W Knuckey
NCX3 knockout mice exhibit increased hippocampal CA1 and CA2 neuronal damage compared to wild-type mice following global cerebral ischemia.
Experimental neurology 2008;210(1):268-73.
2008: Pasquale Molinaro; Ornella Cuomo; GIUSEPPE PIGNATARO; Francesca Boscia; Rossana Sirabella; Anna Pannaccione; Agnese Secondo; Antonella Scorziello; Annagrazia Adornetto; Rosaria Gala; Davide Viggiano; Sophie Sokolow; Andre Herchuelz; Stéphane Schurmans; Gianfranco Di Renzo; Lucio Annunziato
Targeted disruption of Na+/Ca2+ exchanger 3 (NCX3) gene leads to a worsening of ischemic brain damage.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(5):1179-84.
2007: Jing Zhang; Zhenan Liu; Joanne Rasschaert; Daniel Blero; Laurence Deneubourg; Stéphane Schurmans; Christophe Erneux; Xavier Pesesse
SHIP2 controls PtdIns(3,4,5)P(3) levels and PKB activity in response to oxidative stress.
Cellular signalling 2007;19(10):2194-200.
2007: Daniel Blero; Bernard Payrastre; Stéphane Schurmans; Christophe Erneux
Phosphoinositide phosphatases in a network of signalling reactions.
Pflügers Archiv : European journal of physiology 2007;455(1):31-44.
2007: Yonghui Jia; Kulandayan K Subramanian; Christophe Erneux; Valérie Pouillon; Hidenori Hattori; Hakryul Jo; Jian You; Daocheng Zhu; Stéphane Schurmans; Hongbo R Luo
Inositol 1,3,4,5-tetrakisphosphate negatively regulates phosphatidylinositol-3,4,5- trisphosphate signaling in neutrophils.
Immunity 2007;27(3):453-67.
2007: Yoann Maréchal; Xavier Pesesse; Yonghui Jia; Valérie Pouillon; David Pérez-Morga; Julien Daniel; Shozo Izui; Peter J Cullen; Oberdan Leo; Hongbo R Luo; Christophe Erneux; Stéphane Schurmans
Inositol 1,3,4,5-tetrakisphosphate controls proapoptotic Bim gene expression and survival in B cells.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(35):13978-83.
2007: Alexandre Leyman; Valérie Pouillon; Alionka Bostan; Stéphane Schurmans; Christophe Erneux; Xavier Pesesse
The absence of expression of the three isoenzymes of the inositol 1,4,5-trisphosphate 3-kinase does not prevent the formation of inositol pentakisphosphate and hexakisphosphate in mouse embryonic fibroblasts.
Cellular signalling 2007;19(7):1497-504.
2006: Bertrand Bearzatto; Laurent Servais; Céline Roussel; David Gall; Fawzia Baba-Aïssa; Stéphane Schurmans; Alban de Kerchove D'Exaerde; Guy Cheron; Serge N Schiffmann
Targeted calretinin expression in granule cells of calretinin-null mice restores normal cerebellar functions.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(2):380-2.
2005: Daniel Blero; Jing Zhang; Xavier Pesesse; Bernard Payrastre; Jacques E Dumont; Stéphane Schurmans; Christophe Erneux
Phosphatidylinositol 3,4,5-trisphosphate modulation in SHIP2-deficient mouse embryonic fibroblasts.
The FEBS journal 2005;272(10):2512-22.
2005: Jens Behrends; Serge Clément; Bernard Pajak; Viviane Pohl; Carine Maenhaut; Jacques E Dumont; Stéphane Schurmans
Normal thyroid structure and function in rhophilin 2-deficient mice.
Molecular and cellular biology 2005;25(7):2846-52.
2004: Yijie Wang; Rosemary J Keogh; Melissa G Hunter; Christina A Mitchell; Randall S Frey; Kamran Javaid; Asrar B Malik; Stéphane Schurmans; Susheela Tridandapani; Clay B Marsh
SHIP2 is recruited to the cell membrane upon macrophage colony-stimulating factor (M-CSF) stimulation and regulates M-CSF-induced signaling.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(11):6820-30.
2004: Romana Hascakova-Bartova; Valérie Pouillon; Valérie Dewaste; Colette Moreau; Céline Jacques; George Banting; Stéphane Schurmans; Christophe Erneux
Identification and subcellular distribution of endogenous Ins(1,4,5)P(3) 3-kinase B in mouse tissues.
Biochemical and biophysical research communications 2004;323(3):920-5.
2004: Pamela J Kaisaki; Marc Delépine; Peng Y Woon; Liam Sebag-Montefiore; Steven P Wilder; Stephan Menzel; Nathalie Vionnet; Evelyne Marion; Jean-Pierre Riveline; Guillaume Charpentier; Stéphane Schurmans; Jonathan C Levy; Mark Lathrop; Martin Farrall; Dominique Gauguier
Polymorphisms in type II SH2 domain-containing inositol 5-phosphatase (INPPL1, SHIP2) are associated with physiological abnormalities of the metabolic syndrome.
Diabetes 2004;53(7):1900-4.
2004: Sophie Sokolow; Mario-Ubaldo Manto; Philippe Gailly; Jordi Molgó; clarisse vandebrouck; Jean-Marie Vanderwinden; Andre Herchuelz; Stéphane Schurmans
Impaired neuromuscular transmission and skeletal muscle fiber necrosis in mice lacking Na/Ca exchanger 3.
The Journal of clinical investigation 2004;113(2):265-73.
2003: Sylvie Giuriato; Xavier Pesesse; Stephane Bodin; Takehiko Sasaki; Cécile Viala; Evelyne Marion; Joseph Penninger; Stéphane Schurmans; Christophe Erneux; Bernard Payrastre
SH2-containing inositol 5-phosphatases 1 and 2 in blood platelets: their interactions and roles in the control of phosphatidylinositol 3,4,5-trisphosphate levels.
The Biochemical journal 2003;376(Pt 1):199-207.
2003: Valérie Pouillon; Romana Hascakova-Bartova; Bernard Pajak; Emmanuelle Adam; Françoise Bex; Valérie Dewaste; Carine Van Lint; Oberdan Leo; Christophe Erneux; Stéphane Schurmans
Inositol 1,3,4,5-tetrakisphosphate is essential for T lymphocyte development.
Nature immunology 2003;4(11):1136-43.
2003: David Gall; Céline Roussel; Isabella Susa; Egidio D'Angelo; Paola Rossi; Bertrand Bearzatto; Marie-Christine Galas; David Blum; Stéphane Schurmans; Serge N Schiffmann
Altered neuronal excitability in cerebellar granule cells of mice lacking calretinin.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(28):9320-7.
2003: Bernard Robaye; Esam Ghanem; Françoise Wilkin; Dominique Fokan; Willy Van Driessche; Stéphane Schurmans; Jean-Marie Boeynaems; Renaud Beauwens
Loss of nucleotide regulation of epithelial chloride transport in the jejunum of P2Y4-null mice.
Molecular pharmacology 2003;63(4):777-83.
2002: Evelyne Marion; Pamela J Kaisaki; Valérie Pouillon; Cyril Gueydan; Jonathan C Levy; André Bodson; Georges Krzentowski; Jean-Claude Daubresse; Jean Mockel; Jens Behrends; Geneviève Servais; Claude Szpirer; Véronique Kruys; Dominique Gauguier; Stéphane Schurmans
The gene INPPL1, encoding the lipid phosphatase SHIP2, is a candidate for type 2 diabetes in rat and man.
Diabetes 2002;51(7):2012-7.
2002: Sarah Dremier; Katia Coulonval; S Perpete; Fabrice Vandeput; Nathalie Fortemaison; A Van Keymeulen; S Deleu; C Ledent; Serge Clément; Stéphane Schurmans; Jacques E Dumont; Françoise Lamy; Pierre P Roger; Carine Maenhaut
The role of cyclic AMP and its effect on protein kinase A in the mitogenic action of thyrotropin on the thyroid cell.
Annals of the New York Academy of Sciences 2002;968():106-21.
2001: Serge Clément; Samuel Refetoff; Bernard Robaye; Jacques E Dumont; Stéphane Schurmans
Low TSH requirement and goiter in transgenic mice overexpressing IGF-I and IGF-Ir receptor in the thyroid gland.
Endocrinology 2001;142(12):5131-9.
2001: Serge Clément; U Krause; F Desmedt; Jean-François Tanti; Jens Behrends; Xavier Pesesse; T Sasaki; J Penninger; M Doherty; W Malaisse; Jacques E Dumont; Yannick Le Marchand-Brustel; Christophe Erneux; L Hue; Stéphane Schurmans
The lipid phosphatase SHIP2 controls insulin sensitivity.
Nature 2001;409(6816):92-7.
2000: Guy Cheron; Stéphane Schurmans; A Lohof; Pablo d'Alcantara; M Meyer; Jean-Philippe Draye; M Parmentier; Serge N Schiffmann
Electrophysiological behavior of Purkinje cells and motor coordination in calretinin knock-out mice.
Progress in brain research 2000;124():299-308.
1999: Stéphane Schurmans; R Carrió; Jens Behrends; Valérie Pouillon; J Merino; Serge Clément
The mouse SHIP2 (Inppl1) gene: complementary DNA, genomic structure, promoter analysis, and gene expression in the embryo and adult mouse.
Genomics 1999;62(2):260-71.
1999: Serge N Schiffmann; Guy Cheron; A Lohof; Pablo d'Alcantara; M Meyer; M Parmentier; Stéphane Schurmans
Impaired motor coordination and Purkinje cell excitability in mice lacking calretinin.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(9):5257-62.
1999: Isabelle Pirson; Jens Behrends; Valérie Savonet; J C Goffard; Jacques E Dumont; Stéphane Schurmans; Carine Maenhaut
Identification and characterization of mRNAs differentially expressed in thyroid cells stimulated by a mitogenic treatment.
Biochimie 1999;81(4):309-14.
1998: H Gurden; Serge N Schiffmann; M Lemaire; Georg Andrees Bohme; M Parmentier; Stéphane Schurmans
Calretinin expression as a critical component in the control of dentate gyrus long-term potentiation induction in mice.
The European journal of neuroscience 1998;10(9):3029-33.
1997: Stéphane Schurmans; Serge N Schiffmann; H Gurden; M Lemaire; H P Lipp; V Schwam; R Pochet; Assunta Imperato; Georg Andrees Bohme; M Parmentier
Impaired long-term potentiation induction in dentate gyrus of calretinin-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(19):10415-20.
1997: Serge Clément; Jacques E Dumont; Stéphane Schurmans
Loss of calcyphosine gene expression in mouse and other rodents.
Biochemical and biophysical research communications 1997;232(2):407-13.