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Jean-Charles Schwartz

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olivier labeeuw; Jeanne-Marie Lecomte; Nicolas Levoin; Xavier Ligneau; Olivia Poupardin-Olivier; Philippe Robert; Jean-Charles Schwartz; Isabelle Berrebi-Bertrand; Thierry Calmels; Marc Capet
Novel and highly potent histamine H3 receptor ligands. Part 3: An alcohol function to improve the pharmacokinetic profile.
Nicolas Levoin; Olivia Poupardin-Olivier; Jean-Charles Schwartz; Isabelle Berrebi-Bertrand; Thierry Calmels; olivier labeeuw; Jeanne-Marie Lecomte; Marc Capet
Novel and highly potent histamine H3 receptor ligands. Part 1: withdrawing of hERG activity.
olivier labeeuw; Jeanne-Marie Lecomte; Nicolas Levoin; Xavier Ligneau; Olivia Poupardin-Olivier; Philippe Robert; Jean-Charles Schwartz; Isabelle Berrebi-Bertrand; Thierry Calmels; Marc Capet
Novel and highly potent histamine H3 receptor ligands. Part 2: exploring the cyclohexylamine-based series.

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All Publications

2013: olivier labeeuw; Jeanne-Marie Lecomte; Nicolas Levoin; Xavier Ligneau; Olivia Poupardin-Olivier; Philippe Robert; Jean-Charles Schwartz; Isabelle Berrebi-Bertrand; Thierry Calmels; Marc Capet
Novel and highly potent histamine H3 receptor ligands. Part 3: An alcohol function to improve the pharmacokinetic profile.
Bioorganic & medicinal chemistry letters 2013;23(9):2548-54.
2011: Nicolas Levoin; Olivia Poupardin-Olivier; Jean-Charles Schwartz; Isabelle Berrebi-Bertrand; Thierry Calmels; olivier labeeuw; Jeanne-Marie Lecomte; Marc Capet
Novel and highly potent histamine H3 receptor ligands. Part 1: withdrawing of hERG activity.
Bioorganic & medicinal chemistry letters 2011;21(18):5378-83.
2011: olivier labeeuw; Jeanne-Marie Lecomte; Nicolas Levoin; Xavier Ligneau; Olivia Poupardin-Olivier; Philippe Robert; Jean-Charles Schwartz; Isabelle Berrebi-Bertrand; Thierry Calmels; Marc Capet
Novel and highly potent histamine H3 receptor ligands. Part 2: exploring the cyclohexylamine-based series.
Bioorganic & medicinal chemistry letters 2011;21(18):5384-8.
2010: M Walter; Y von Coburg; K Isensee; K Sander; Xavier Ligneau; Jean-Claude Camelin; Jean-Charles Schwartz; Holger Stark
Azole derivatives as histamine H3 receptor antagonists, part I: thiazol-2-yl ethers.
Bioorganic & medicinal chemistry letters 2010;20(19):5879-82.
2010: M Walter; K Isensee; T Kottke; Xavier Ligneau; Jean-Claude Camelin; Jean-Charles Schwartz; Holger Stark
Azole derivatives as histamine H3 receptor antagonists, part 2: C-C and C-S coupled heterocycles.
Bioorganic & medicinal chemistry letters 2010;20(19):5883-6.
2010: Kerstin Sander; Tim Kottke; Claas Hoffend; Miriam Walter; Lilia Weizel; Jean-Claude Camelin; Xavier Ligneau; Erich H Schneider; Roland Seifert; Jean-Charles Schwartz; Holger Stark
First metal-containing histamine H3 receptor ligands.
Organic letters 2010;12(11):2578-81.
2010: Kerstin Sander; Yvonne von Coburg; Jean-Claude Camelin; Xavier Ligneau; Oliver Rau; Manfred Schubert-Zsilavecz; Jean-Charles Schwartz; Holger Stark
Acidic elements in histamine H(3) receptor antagonists.
Bioorganic & medicinal chemistry letters 2010;20(5):1581-4.
2009: K Isensee; M Amon; A Garlapati; A Galaparti; Xavier Ligneau; Jean-Claude Camelin; M Capet; Jean-Charles Schwartz; Holger Stark
Fluorinated non-imidazole histamine H3 receptor antagonists.
Bioorganic & medicinal chemistry letters 2009;19(8):2172-5.
2009: K J Kuder; Xavier Ligneau; J-C Camelin; Dorota Lazewska; Jean-Charles Schwartz; Walter Schunack; Holger Stark; K Kieć-Kononowicz
Diether (substituted) piperidine derivatives as novel, histamine H3 receptor ligands.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2009;58 Suppl 1():47-8.
2008: Dorota Łazewska; Kamil Kuder; Xavier Ligneau; Jean-Charles Schwartz; Walter Schunack; Holger Stark; Katarzyna Kieć-Kononowicz
Piperidine variations in search for non-imidazole histamine H(3) receptor ligands.
Bioorganic & medicinal chemistry 2008;16(18):8729-36.
2008: Jian-Sheng Lin; Yves Dauvilliers; Isabelle Arnulf; Hélène Bastuji; Christelle Anaclet; Régis Parmentier; Laurence Kocher; Masashi Yanagisawa; Philippe Lehert; Xavier Ligneau; David Perrin; Philippe Robert; Michel Roux; Jeanne-Marie Lecomte; Jean-Charles Schwartz
An inverse agonist of the histamine H(3) receptor improves wakefulness in narcolepsy: studies in orexin-/- mice and patients.
Neurobiology of disease 2008;30(1):74-83.
2007: Michael Amon; Xavier Ligneau; Jean-Claude Camelin; Isabelle Berrebi-Bertrand; Jean-Charles Schwartz; Holger Stark
Highly potent fluorescence-tagged nonimidazole histamine H3 receptor ligands.
ChemMedChem 2007;2(5):708-16.
2007: Xavier Ligneau; Laurent Landais; David Perrin; Johanne Piriou; Marilyne Uguen; Emmanuel Denis; Philippe Robert; Régis Parmentier; Christelle Anaclet; Jian-Sheng Lin; Aude Burban; Jean-Michel Arrang; Jean-Charles Schwartz
Brain histamine and schizophrenia: potential therapeutic applications of H3-receptor inverse agonists studied with BF2.649.
Biochemical pharmacology 2007;73(8):1215-24.
2007: Oliver Saur; Anneke E Hackling; Sylvie Perachon; Jean-Charles Schwartz; Pierre Sokoloff; Holger Stark
N-(4-(4-(2-Halogenophenyl)piperazin-1-yl)butyl) substituted cinnamoyl amide derivatives as dopamine D2 and D3 receptor ligands.
Archiv der Pharmazie 2007;340(4):178-84.
2007: Xavier Ligneau; D Perrin; L Landais; Jean-Claude Camelin; T P G Calmels; Isabelle Berrebi-Bertrand; J-M Lecomte; Régis Parmentier; Christelle Anaclet; Jian-Sheng Lin; Valérie Bertaina-Anglade; Christophe Drieu La Rochelle; F d'Aniello; Agnès Rouleau; Florence Gbahou; Jean-Michel Arrang; C Robin Ganellin; Holger Stark; Walter Schunack; Jean-Charles Schwartz
BF2.649 [1-{3-[3-(4-Chlorophenyl)propoxy]propyl}piperidine, hydrochloride], a nonimidazole inverse agonist/antagonist at the human histamine H3 receptor: Preclinical pharmacology.
The Journal of pharmacology and experimental therapeutics 2007;320(1):365-75.
2006: Raphaël Faucard; Vincent Armand; Anne Héron; Véronique Cochois; Jean-Charles Schwartz; Jean-Michel Arrang
N-methyl-D-aspartate receptor antagonists enhance histamine neuron activity in rodent brain.
Journal of neurochemistry 2006;98(5):1487-96.
2006: Dorota Łazewska; Xavier Ligneau; Jean-Charles Schwartz; Walter Schunack; Holger Stark; Katarzyna Kieć-Kononowicz
Ether derivatives of 3-piperidinopropan-1-ol as non-imidazole histamine H3 receptor antagonists.
Bioorganic & medicinal chemistry 2006;14(10):3522-9.
2006: Michael Amon; Xavier Ligneau; Jean-Charles Schwartz; Holger Stark
Fluorescent non-imidazole histamine H3 receptor ligands with nanomolar affinities.
Bioorganic & medicinal chemistry letters 2006;16(7):1938-40.
2005: C Robin Ganellin; Paul B Bishop; Ramesh B Bambal; Suzanne M T Chan; Bertrand Leblond; Andrew N J Moore; Lihua Zhao; Pierre Bourgeat; Christiane Rose; Froylan Vargas; Jean-Charles Schwartz
Inhibitors of tripeptidyl peptidase II. 3. Derivation of butabindide by successive structure optimizations leading to a potential general approach to designing exopeptidase inhibitors.
Journal of medicinal chemistry 2005;48(23):7333-42.
2005: Philipp Heidler; Vida Zohrabi-Kalantari; Thierry Calmels; Marc Capet; Isabelle Berrebi-Bertrand; Jean-Charles Schwartz; Holger Stark; Andreas Link
Parallel synthesis and dopamine D3/D2 receptor screening of novel {4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl}carboxamides.
Bioorganic & medicinal chemistry 2005;13(6):2009-14.
2005: Joachim Apelt; Sven Grassmann; Xavier Ligneau; Heinz H Pertz; C Robin Ganellin; Jean-Michel Arrang; Jean-Charles Schwartz; Walter Schunack; Holger Stark
Search for histamine H3 receptor antagonists with combined inhibitory potency at Ntau-methyltransferase: ether derivatives.
Die Pharmazie 2005;60(2):97-106.
2004: Sven Grassmann; Joachim Apelt; Xavier Ligneau; Heinz H Pertz; Jean-Michel Arrang; C Robin Ganellin; Jean-Charles Schwartz; Walter Schunack; Holger Stark
Search for histamine H(3) receptor ligands with combined inhibitory potency at histamine N-methyltransferase: omega-piperidinoalkanamine derivatives.
Archiv der Pharmazie 2004;337(10):533-45.
2004: Agnès Rouleau; Anne Héron; Véronique Cochois; Catherine Pillot; Jean-Charles Schwartz; Jean-Michel Arrang
Cloning and expression of the mouse histamine H3 receptor: evidence for multiple isoforms.
Journal of neurochemistry 2004;90(6):1331-8.
2004: Nadia Pelloux-Léon; Abdellatif Fkyerat; Antonia Piripitsi; Wasyl Tertiuk; Walter Schunack; Holger Stark; Monique Garbarg; Xavier Ligneau; Jean-Michel Arrang; Jean-Charles Schwartz; C Robin Ganellin
Meta-substituted aryl(thio)ethers as potent partial agonists (or antagonists) for the histamine H3 receptor lacking a nitrogen atom in the side chain.
Journal of medicinal chemistry 2004;47(12):3264-74.
2004: Tibor Mikó; Xavier Ligneau; Heinz H Pertz; Jean-Michel Arrang; C Robin Ganellin; Jean-Charles Schwartz; Walter Schunack; Holger Stark
Structural variations of 1-(4-(phenoxymethyl)benzyl)piperidines as nonimidazole histamine H3 receptor antagonists.
Bioorganic & medicinal chemistry 2004;12(10):2727-36.
2004: Galina Meier; Michael Krause; Annette Hüls; Xavier Ligneau; Heinz H Pertz; Jean-Michel Arrang; C Robin Ganellin; Jean-Charles Schwartz; Walter Schunack; Holger Stark
4-(omega-(alkyloxy)alkyl)-1H-imidazole derivatives as histamine H(3) receptor antagonists/agonists.
Journal of medicinal chemistry 2004;47(10):2678-87.
2004: Ulrich R Mach; Anneke E Hackling; Sylvie Perachon; Sandrine Ferry; Camille G Wermuth; Jean-Charles Schwartz; Pierre Sokoloff; Holger Stark
Development of novel 1,2,3,4-tetrahydroisoquinoline derivatives and closely related compounds as potent and selective dopamine D3 receptor ligands.
Chembiochem : a European journal of chemical biology 2004;5(4):508-18.
2004: Olivier Guillin; Nathalie Griffon; Jorge Diaz; Bernard Le Foll; Erwan Bezard; Christian Gross; Chris Lammers; Holger Stark; Patrick Carroll; Jean-Charles Schwartz; Pierre Sokoloff
Brain-derived neurotrophic factor and the plasticity of the mesolimbic dopamine pathway.
International review of neurobiology 2004;59():425-44.
2003: Florence Gbahou; Agnès Rouleau; Séverine Morisset; Régis Parmentier; Sylvain Crochet; Jian-Sheng Lin; Xavier Ligneau; Joël Tardivel-Lacombe; Holger Stark; Walter Schunack; C Robin Ganellin; Jean-Charles Schwartz; Jean-Michel Arrang
Protean agonism at histamine H3 receptors in vitro and in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(19):11086-91.
2003: Anneke E Hackling; Robin Ghosh; Sylvie Perachon; André Mann; Hans-Dieter Höltje; Camille G Wermuth; Jean-Charles Schwartz; Wolfgang Sippl; Pierre Sokoloff; Holger Stark
N-(omega-(4-(2-methoxyphenyl)piperazin-1-yl)alkyl)carboxamides as dopamine D2 and D3 receptor ligands.
Journal of medicinal chemistry 2003;46(18):3883-99.
2003: Ludovic Leriche; Jean-Charles Schwartz; Pierre Sokoloff
The dopamine D3 receptor mediates locomotor hyperactivity induced by NMDA receptor blockade.
Neuropharmacology 2003;45(2):174-81.
2003: Sven Grassmann; Joachim Apelt; Wolfgang Sippl; Xavier Ligneau; Heinz H Pertz; Yuan Hui Zhao; Jean-Michel Arrang; C Robin Ganellin; Jean-Charles Schwartz; Walter Schunack; Holger Stark
Imidazole derivatives as a novel class of hybrid compounds with inhibitory histamine N-methyltransferase potencies and histamine hH3 receptor affinities.
Bioorganic & medicinal chemistry 2003;11(10):2163-74.
2003: Tibor Mikó; Xavier Ligneau; Heinz H Pertz; C Robin Ganellin; Jean-Michel Arrang; Jean-Charles Schwartz; Walter Schunack; Holger Stark
Novel nonimidazole histamine H3 receptor antagonists: 1-(4-(phenoxymethyl)benzyl)piperidines and related compounds.
Journal of medicinal chemistry 2003;46(8):1523-30.
2003: Bernard Le Foll; Jean-Charles Schwartz; Pierre Sokoloff
Disruption of nicotine conditioning by dopamine D(3) receptor ligands.
Molecular psychiatry 2003;8(2):225-30.
2003: Jean-Charles Schwartz; Séverine Morisset; Agnès Rouleau; Xavier Ligneau; Florence Gbahou; Joël Tardivel-Lacombe; Holger Stark; Walter Schunack; C Robin Ganellin; Jean-Michel Arrang
Therapeutic implications of constitutive activity of receptors: the example of the histamine H3 receptor.
Journal of neural transmission. Supplementum 2003;(64):1-16.
2003: P Facchinetti; Christiane Rose; Jean-Charles Schwartz; Tanja Ouimet
Ontogeny, regional and cellular distribution of the novel metalloprotease neprilysin 2 in the rat: a comparison with neprilysin and endothelin-converting enzyme-1.
Neuroscience 2003;118(3):627-39.
2003: Catherine Pillot; Anne Héron; Jean-Charles Schwartz; Jean-Michel Arrang
Ciproxifan, a histamine H3-receptor antagonist/inverse agonist, modulates the effects of methamphetamine on neuropeptide mRNA expression in rat striatum.
The European journal of neuroscience 2003;17(2):307-14.
2002: Astrid Sasse; Xavier Ligneau; Agnès Rouleau; Sigurd Elz; C Robin Ganellin; Jean-Michel Arrang; Jean-Charles Schwartz; Walter Schunack; Holger Stark
Influence of bulky substituents on histamine h(3) receptor agonist/antagonist properties.
Journal of medicinal chemistry 2002;45(18):4000-10.
2002: Catherine Pillot; Jordi Ortiz; Anne Héron; Sophie Ridray; Jean-Charles Schwartz; Jean-Michel Arrang
Ciproxifan, a histamine H3-receptor antagonist/inverse agonist, potentiates neurochemical and behavioral effects of haloperidol in the rat.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(16):7272-80.
2002: Galina Meier; Xavier Ligneau; Heinz H Pertz; C Robin Ganellin; Jean-Charles Schwartz; Walter Schunack; Holger Stark
Piperidino-hydrocarbon compounds as novel non-imidazole histamine H(3)-receptor antagonists.
Bioorganic & medicinal chemistry 2002;10(8):2535-42.
2002: Suzanne Trottier; Carole Chotard; E Traiffort; U Unmehopa; B Fisser; Dick F Swaab; Jean-Charles Schwartz
Co-localization of histamine with GABA but not with galanin in the human tuberomamillary nucleus.
Brain research 2002;939(1-2):52-64.
2002: Bernard Le Foll; Henriette Francès; Jorge Diaz; Jean-Charles Schwartz; Pierre Sokoloff
Role of the dopamine D3 receptor in reactivity to cocaine-associated cues in mice.
The European journal of neuroscience 2002;15(12):2016-26.
2002: Sven Grassmann; Bassem Sadek; Xavier Ligneau; Sigurd Elz; C Robin Ganellin; Jean-Michel Arrang; Jean-Charles Schwartz; Holger Stark; Walter Schunack
Progress in the proxifan class: heterocyclic congeners as novel potent and selective histamine H(3)-receptor antagonists.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2002;15(4):367-78.
2002: Christiane Rose; Stéphanie Voisin; Claude Gros; Jean-Charles Schwartz; Tanja Ouimet
Cell-specific activity of neprilysin 2 isoforms and enzymic specificity compared with neprilysin.
The Biochemical journal 2002;363(Pt 3):697-705.
2002: M Wiecek; K Kieć-Kononowicz; Astrid Sasse; Xavier Ligneau; Jean-Charles Schwartz; Walter Schunack; Holger Stark
Impact of lipophilicity on the pharmacological properties of histamine H3-receptor antagonists of the cycloalkyl carbamate class.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2002;51 Suppl 1():S71-2.
2002: Carole Chotard; Tanja Ouimet; S Morisset; U Sahm; Jean-Charles Schwartz; Suzanne Trottier
Effects of histamine H3 receptor agonist and antagonist on histamine co-transmitter expression in rat brain.
Journal of neural transmission (Vienna, Austria : 1996) 2002;109(3):293-306.
2002: Joachim Apelt; Xavier Ligneau; Heinz H Pertz; Jean-Michel Arrang; C Robin Ganellin; Jean-Charles Schwartz; Walter Schunack; Holger Stark
Development of a new class of nonimidazole histamine H(3) receptor ligands with combined inhibitory histamine N-methyltransferase activity.
Journal of medicinal chemistry 2002;45(5):1128-41.
2002: Séverine Morisset; C Pilon; Joël Tardivel-Lacombe; D Weinstein; W Rostene; C Betancur; Pierre Sokoloff; Jean-Charles Schwartz; Jean-Michel Arrang
Acute and chronic effects of methamphetamine on tele-methylhistamine levels in mouse brain: selective involvement of the D(2) and not D(3) receptor.
The Journal of pharmacology and experimental therapeutics 2002;300(2):621-8.
2002: Catherine Pillot; A Heron; Véronique Cochois; Joël Tardivel-Lacombe; Xavier Ligneau; Jean-Charles Schwartz; Jean-Michel Arrang
A detailed mapping of the histamine H(3) receptor and its gene transcripts in rat brain.
Neuroscience 2002;114(1):173-93.
2002: Agnès Rouleau; Xavier Ligneau; Joël Tardivel-Lacombe; Séverine Morisset; Florence Gbahou; Jean-Charles Schwartz; Jean-Michel Arrang
Histamine H3-receptor-mediated [35S]GTP gamma[S] binding: evidence for constitutive activity of the recombinant and native rat and human H3 receptors.
British journal of pharmacology 2002;135(2):383-92.
2001: Jean-Charles Schwartz; Séverine Morisset; Agnès Rouleau; Joël Tardivel-Lacombe; Florence Gbahou; Xavier Ligneau; Anne Héron; Astrid Sasse; Holger Stark; Walter Schunack; R C Ganellin; Jean-Michel Arrang
Application of genomics to drug design: the example of the histamine H3 receptor.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2001;11(6):441-8.
2001: Pierre Sokoloff; Bernard Le Foll; Sylvie Perachon; R Bordet; S Ridray; Jean-Charles Schwartz
The dopamine D3 receptor and drug addiction.
Neurotoxicity research 2001;3(5):433-41.
2001: Anne Héron; Agnès Rouleau; Véronique Cochois; Catherine Pillot; Jean-Charles Schwartz; Jean-Michel Arrang
Expression analysis of the histamine H(3) receptor in developing rat tissues.
Mechanisms of development 2001;105(1-2):167-73.
2001: Galina Meier; Joachim Apelt; Uwe Reichert; Sven Grassmann; Xavier Ligneau; Sigurd Elz; F Leurquin; C Robin Ganellin; Jean-Charles Schwartz; Walter Schunack; Holger Stark
Influence of imidazole replacement in different structural classes of histamine H(3)-receptor antagonists.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2001;13(3):249-59.
2001: Olivier Guillin; Jorge Diaz; P Carroll; Nathalie Griffon; Jean-Charles Schwartz; Pierre Sokoloff
BDNF controls dopamine D3 receptor expression and triggers behavioural sensitization.
Nature 2001;411(6833):86-9.
2001: Holger Stark; Wolfgang Sippl; Xavier Ligneau; Jean-Michel Arrang; C Robin Ganellin; Jean-Charles Schwartz; Walter Schunack
Different antagonist binding properties of human and rat histamine H3 receptors.
Bioorganic & medicinal chemistry letters 2001;11(7):951-4.
2001: Joël Tardivel-Lacombe; Séverine Morisset; Florence Gbahou; Jean-Charles Schwartz; Jean-Michel Arrang
Chromosomal mapping and organization of the human histamine H3 receptor gene.
Neuroreport 2001;12(2):321-4.
2001: Astrid Sasse; Xavier Ligneau; Bassem Sadek; Sigurd Elz; Heinz H Pertz; C Robin Ganellin; Jean-Michel Arrang; Jean-Charles Schwartz; Walter Schunack; Holger Stark
Benzophenone derivatives and related compounds as potent histamine H3-receptor antagonists and potential PET/SPECT ligands.
Archiv der Pharmazie 2001;334(2):45-52.
2001: Séverine Morisset; Astrid Sasse; Florence Gbahou; Anne Héron; Xavier Ligneau; Joël Tardivel-Lacombe; Jean-Charles Schwartz; Jean-Michel Arrang
The rat H3 receptor: gene organization and multiple isoforms.
Biochemical and biophysical research communications 2001;280(1):75-80.
2001: Holger Stark; Jean-Michel Arrang; Xavier Ligneau; Monique Garbarg; C Robin Ganellin; Jean-Charles Schwartz; Walter Schunack
The histamine H3 receptor and its ligands.
Progress in medicinal chemistry 2001;38():279-308.
2001: Holger Stark; Michael Krause; Agnès Rouleau; Monique Garbarg; Jean-Charles Schwartz; Walter Schunack
Enzyme-catalyzed prodrug approaches for the histamine H3-receptor agonist (R)-alpha-methylhistamine.
Bioorganic & medicinal chemistry 2001;9(1):191-8.
2000: Séverine Morisset; Agnès Rouleau; Xavier Ligneau; Florence Gbahou; Joël Tardivel-Lacombe; Holger Stark; Walter Schunack; C Robin Ganellin; Jean-Charles Schwartz; Jean-Michel Arrang
High constitutive activity of native H3 receptors regulates histamine neurons in brain.
Nature 2000;408(6814):860-4.
2000: Jorge Diaz; C Pilon; Bernard Le Foll; C Gros; Antoine Triller; Jean-Charles Schwartz; Pierre Sokoloff
Dopamine D3 receptors expressed by all mesencephalic dopamine neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(23):8677-84.
2000: Xavier Ligneau; Séverine Morisset; Joël Tardivel-Lacombe; Florence Gbahou; C Robin Ganellin; Holger Stark; Walter Schunack; Jean-Charles Schwartz; Jean-Michel Arrang
Distinct pharmacology of rat and human histamine H(3) receptors: role of two amino acids in the third transmembrane domain.
British journal of pharmacology 2000;131(7):1247-50.
2000: Holger Stark; Bassem Sadek; Michael Krause; Annette Hüls; Xavier Ligneau; C Robin Ganellin; Jean-Michel Arrang; Jean-Charles Schwartz; Walter Schunack
Novel histamine H(3)-receptor antagonists with carbonyl-substituted 4-(3-(phenoxy)propyl)-1H-imidazole structures like ciproxifan and related compounds.
Journal of medicinal chemistry 2000;43(21):3987-94.
2000: Holger Stark; Xavier Ligneau; Bassem Sadek; C Robin Ganellin; Jean-Michel Arrang; Jean-Charles Schwartz; Walter Schunack
Analogues and derivatives of ciproxifan, a novel prototype for generating potent histamine H3-receptor antagonists.
Bioorganic & medicinal chemistry letters 2000;10(20):2379-82.
2000: G Drutel; Markus Kathmann; Anne Héron; Claude Gros; S Macé; Jean-Charles Schwartz; Jean-Michel Arrang
Two splice variants of the hypoxia-inducible factor HIF-1alpha as potential dimerization partners of ARNT2 in neurons.
The European journal of neuroscience 2000;12(10):3701-8.
2000: Agnès Rouleau; Holger Stark; Walter Schunack; Jean-Charles Schwartz
Anti-inflammatory and antinociceptive properties of BP 2-94, a histamine H(3)-receptor agonist prodrug.
The Journal of pharmacology and experimental therapeutics 2000;295(1):219-25.
2000: Marie-Odile Krebs; Olivier Guillin; M C Bourdell; Jean-Charles Schwartz; Jean-Pierre Olie; Marie-France Poirier; Pierre Sokoloff
Brain derived neurotrophic factor (BDNF) gene variants association with age at onset and therapeutic response in schizophrenia.
Molecular psychiatry 2000;5(5):558-62.
2000: Astrid Sasse; Bassem Sadek; Xavier Ligneau; Sigurd Elz; Heinz H Pertz; Peter Luger; C Robin Ganellin; Jean-Michel Arrang; Jean-Charles Schwartz; Walter Schunack; Holger Stark
New histamine H(3)-receptor ligands of the proxifan series: imoproxifan and other selective antagonists with high oral in vivo potency.
Journal of medicinal chemistry 2000;43(17):3335-43.
2000: Claas-Hinrich Lammers; Jorge Diaz; Jean-Charles Schwartz; Pierre Sokoloff
Selective increase of dopamine D3 receptor gene expression as a common effect of chronic antidepressant treatments.
Molecular psychiatry 2000;5(4):378-88.
2000: R Bordet; S Ridray; Jean-Charles Schwartz; Pierre Sokoloff
Involvement of the direct striatonigral pathway in levodopa-induced sensitization in 6-hydroxydopamine-lesioned rats.
The European journal of neuroscience 2000;12(6):2117-23.
2000: Tanja Ouimet; P Facchinetti; Christiane Rose; M C Bonhomme; Claude Gros; Jean-Charles Schwartz; O Tanja
Neprilysin II: A putative novel metalloprotease and its isoforms in CNS and testis.
Biochemical and biophysical research communications 2000;271(3):565-70.
2000: K Kieć-Kononowicz; M Wiecek; Astrid Sasse; Xavier Ligneau; Sigurd Elz; C Robin Ganellin; Jean-Charles Schwartz; Holger Stark; Walter Schunack
Importance of the lipophilic group in carbamates having histamine H3-receptor antagonist activity.
Die Pharmazie 2000;55(5):349-55.
2000: Claas-Hinrich Lammers; Jorge Diaz; Jean-Charles Schwartz; Pierre Sokoloff
Dopamine D3 receptor gene expression in the shell of nucleus accumbens is increased by chronic antidepressant treatment.
Molecular psychiatry 2000;5(3):229.
2000: Astrid Sasse; Holger Stark; Xavier Ligneau; Sigurd Elz; S Reidemeister; C Robin Ganellin; Jean-Charles Schwartz; Walter Schunack
(Partial) agonist/antagonist properties of novel diarylalkyl carbamates on histamine H3 receptors.
Bioorganic & medicinal chemistry 2000;8(5):1139-49.
2000: Joël Tardivel-Lacombe; Agnès Rouleau; Anne Héron; Séverine Morisset; Catherine Pillot; Véronique Cochois; Jean-Charles Schwartz; Jean-Michel Arrang
Cloning and cerebral expression of the guinea pig histamine H3 receptor: evidence for two isoforms.
Neuroreport 2000;11(4):755-9.
2000: C Ito; Séverine Morisset; Marie-Odile Krebs; Jean-Pierre Olié; Henri Lôo; Marie-France Poirier; Lars Lannfelt; Jean-Charles Schwartz; Jean-Michel Arrang
Histamine H2 receptor gene variants: lack of association with schizophrenia.
Molecular psychiatry 2000;5(2):159-64.
2000: Jean-Charles Schwartz; Jorge Diaz; C Pilon; Pierre Sokoloff
Possible implications of the dopamine D(3) receptor in schizophrenia and in antipsychotic drug actions.
Brain research. Brain research reviews 2000;31(2-3):277-87.
2000: C Robin Ganellin; P B Bishop; R B Bambal; S M Chan; J K Law; B Marabout; P M Luthra; A N Moore; O Peschard; P Bourgeat; C Rose; F Vargas; Jean-Charles Schwartz
Inhibitors of tripeptidyl peptidase II. 2. Generation of the first novel lead inhibitor of cholecystokinin-8-inactivating peptidase: a strategy for the design of peptidase inhibitors.
Journal of medicinal chemistry 2000;43(4):664-74.
2000: S Reidemeister; Holger Stark; Xavier Ligneau; C Robin Ganellin; Jean-Charles Schwartz; Walter Schunack
Substituted N-phenylcarbamates as histamine H3 receptor antagonists with improved in vivo potency.
Die Pharmazie 2000;55(2):83-6.
2000: Sylvie Perachon; C Betancur; C Pilon; William Rostène; Jean-Charles Schwartz; Pierre Sokoloff
Role of dopamine D3 receptors in thermoregulation: a reappraisal.
Neuroreport 2000;11(1):221-5.
2000: Séverine Morisset; Elisabeth Traiffort; Jean-Michel Arrang; Jean-Charles Schwartz
Changes in histamine H3 receptor responsiveness in mouse brain.
Journal of neurochemistry 2000;74(1):339-46.
1999: Astrid Sasse; Holger Stark; S Reidemeister; Annette Hüls; Sigurd Elz; Xavier Ligneau; C Robin Ganellin; Jean-Charles Schwartz; Walter Schunack
Novel partial agonists for the histamine H(3) receptor with high in vitro and in vivo activity.
Journal of medicinal chemistry 1999;42(20):4269-74.
1999: M Pilla; Sylvie Perachon; F Sautel; F Garrido; A Mann; Camille G Wermuth; Jean-Charles Schwartz; Barry J Everitt; Pierre Sokoloff
Selective inhibition of cocaine-seeking behaviour by a partial dopamine D3 receptor agonist.
Nature 1999;400(6742):371-5.
1999: G Drutel; Anne Héron; Markus Kathmann; Claude Gros; S Macé; M Plotkine; Jean-Charles Schwartz; Jean-Michel Arrang
ARNT2, a transcription factor for brain neuron survival?
The European journal of neuroscience 1999;11(5):1545-53.
1999: Julien Allard; Sonia Barron; Suzanne Trottier; Pascale Cervera; Catherine Daumas-Duport; E Leguern; Alexis Brice; Jean-Charles Schwartz; Pierre Sokoloff
Edg-2 in myelin-forming cells: isoforms, genomic mapping, and exclusion in Charcot-Marie-Tooth disease.
Glia 1999;26(2):176-85.
1999: Astrid Sasse; Katarzyna Kiec-Kononowicz; Holger Stark; Maciej Motyl; S Reidemeister; C Robin Ganellin; Xavier Ligneau; Jean-Charles Schwartz; Walter Schunack
Development of chiral N-alkylcarbamates as new leads for potent and selective H3-receptor antagonists: synthesis, capillary electrophoresis, and in vitro and oral in vivo activity.
Journal of medicinal chemistry 1999;42(4):593-600.
1999: Sylvie Perachon; Jean-Charles Schwartz; Pierre Sokoloff
Functional potencies of new antiparkinsonian drugs at recombinant human dopamine D1, D2 and D3 receptors.
European journal of pharmacology 1999;366(2-3):293-300.
1999: Séverine Morisset; U G Sahm; Elisabeth Traiffort; Joël Tardivel-Lacombe; Jean-Michel Arrang; Jean-Charles Schwartz
Atypical neuroleptics enhance histamine turnover in brain via 5-Hydroxytryptamine2A receptor blockade.
The Journal of pharmacology and experimental therapeutics 1999;288(2):590-6.
1999: P Facchinetti; C Rose; Philippe Rostaing; Antoine Triller; Jean-Charles Schwartz
Immunolocalization of tripeptidyl peptidase II, a cholecystokinin-inactivating enzyme, in rat brain.
Neuroscience 1999;88(4):1225-40.
1998: C Robin Ganellin; F Leurquin; A Piripitsi; Jean-Michel Arrang; Monique Garbarg; Xavier Ligneau; Walter Schunack; Jean-Charles Schwartz
Synthesis of potent non-imidazole histamine H3-receptor antagonists.
Archiv der Pharmazie 1998;331(12):395-404.
1998: Michael Krause; Xavier Ligneau; Holger Stark; Monique Garbarg; Jean-Charles Schwartz; Walter Schunack
4-Alkynylphenyl imidazolylpropyl ethers as selective histamine H3-receptor antagonists with high oral central nervous system activity.
Journal of medicinal chemistry 1998;41(21):4171-6.
1998: Holger Stark; Xavier Ligneau; Jean-Michel Arrang; Jean-Charles Schwartz; Walter Schunack
General construction pattern of histamine H3-receptor antagonists: change of a paradigm.
Bioorganic & medicinal chemistry letters 1998;8(15):2011-6.
1998: Caroline Dubertret; Philip Gorwood; J Ades; J Feingold; Jean-Charles Schwartz; Pierre Sokoloff
Meta-analysis of DRD3 gene and schizophrenia: ethnic heterogeneity and significant association in Caucasians.
American journal of medical genetics 1998;81(4):318-22.
1998: Marie-Odile Krebs; F Sautel; Marie-Chantal Bourdel; Pierre Sokoloff; Jean-Charles Schwartz; Jean-Pierre Olié; Henri Lôo; Marie-France Poirier
Dopamine D3 receptor gene variants and substance abuse in schizophrenia.
Molecular psychiatry 1998;3(4):337-41.
1998: E Duaux; Philip Gorwood; Nathalie Griffon; Marie-Chantal Bourdel; F Sautel; Pierre Sokoloff; Jean-Charles Schwartz; J Ades; Henri Lôo; Marie-France Poirier
Homozygosity at the dopamine D3 receptor gene is associated with opiate dependence.
Molecular psychiatry 1998;3(4):333-6.
1998: Holger Stark; Annette Hüls; Xavier Ligneau; K Purand; Heinz H Pertz; Jean-Michel Arrang; Jean-Charles Schwartz; Walter Schunack
Development of FUB 181, a selective histamine H3-receptor antagonist of high oral in vivo potency with 4-(omega-(arylalkyloxy)alkyl)-1H-imidazole structure.
Archiv der Pharmazie 1998;331(6):211-8.
1998: S Ridray; Nathalie Griffon; V Mignon; Evelyne Souil; S Carboni; Jorge Diaz; Jean-Charles Schwartz; Pierre Sokoloff
Coexpression of dopamine D1 and D3 receptors in islands of Calleja and shell of nucleus accumbens of the rat: opposite and synergistic functional interactions.
The European journal of neuroscience 1998;10(5):1676-86.
1998: Jean-Charles Schwartz; Jorge Diaz; R Bordet; Nathalie Griffon; Sylvie Perachon; C Pilon; S Ridray; Pierre Sokoloff
Functional implications of multiple dopamine receptor subtypes: the D1/D3 receptor coexistence.
Brain research. Brain research reviews 1998;26(2-3):236-42.
1998: Julien Allard; S Barrón; J Diaz; Catherine Lubetzki; Bernard Zalc; Jean-Charles Schwartz; Pierre Sokoloff
A rat G protein-coupled receptor selectively expressed in myelin-forming cells.
The European journal of neuroscience 1998;10(3):1045-53.
1998: Pierre Sokoloff; Jorge Diaz; R Bordet; Nathalie Griffon; Sylvie Perachon; C Pilon; S Ridray; Jean-Charles Schwartz
[Function and therapeutic potential of the dopamine D3 receptor].
Comptes rendus des séances de la Société de biologie et de ses filiales 1998;192(6):1111-25.
1998: Jean-Charles Schwartz; S Ridray; R Bordet; Jorge Diaz; Pierre Sokoloff
D1/D3 receptor relationships in brain coexpression, coactivation, and coregulation.
Advances in pharmacology (San Diego, Calif.) 1998;42():408-11.
1997: Marisa Vizuete; Elisabeth Traiffort; M L Bouthenet; Martial Ruat; Evelyne Souil; Joël Tardivel-Lacombe; Jean-Charles Schwartz
Detailed mapping of the histamine H2 receptor and its gene transcripts in guinea-pig brain.
Neuroscience 1997;80(2):321-43.
1997: Holger Stark; Annette Hüls; Xavier Ligneau; Jean-Michel Arrang; Jean-Charles Schwartz; Walter Schunack
Search for novel leads for histamine H3-receptor antagonists: oxygen-containing derivatives.
Die Pharmazie 1997;52(7):495-500.
1997: Holger Stark; Xavier Ligneau; R Lipp; Jean-Michel Arrang; Jean-Charles Schwartz; Walter Schunack
Search for novel leads for histamine H3-receptor antagonists: amine derivatives.
Die Pharmazie 1997;52(6):419-23.
1997: Agnès Rouleau; Monique Garbarg; Xavier Ligneau; C Mantion; P Lavie; C Advenier; J M Lecomte; Michael Krause; Holger Stark; Walter Schunack; Jean-Charles Schwartz
Bioavailability, antinociceptive and antiinflammatory properties of BP 2-94, a histamine H3 receptor agonist prodrug.
The Journal of pharmacology and experimental therapeutics 1997;281(3):1085-94.
1997: Jorge Diaz; S Ridray; V Mignon; Nathalie Griffon; Jean-Charles Schwartz; Pierre Sokoloff
Selective expression of dopamine D3 receptor mRNA in proliferative zones during embryonic development of the rat brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(11):4282-92.
1997: R Bordet; S Ridray; S Carboni; Jorge Diaz; Pierre Sokoloff; Jean-Charles Schwartz
Induction of dopamine D3 receptor expression as a mechanism of behavioral sensitization to levodopa.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(7):3363-7.
1997: V Dimitriadou; Agnès Rouleau; M D Trung Tuong; G J Newlands; Hugh Miller; G Luffau; Jean-Charles Schwartz; Monique Garbarg
Functional relationships between sensory nerve fibers and mast cells of dura mater in normal and inflammatory conditions.
Neuroscience 1997;77(3):829-39.
1997: Agnès Rouleau; V Dimitriadou; M D Trung Tuong; GF Newlands; Hugh Miller; Jean-Charles Schwartz; Monique Garbarg
Mast cell specific proteases in rat brain: changes in rats with experimental allergic encephalomyelitis.
Journal of neural transmission (Vienna, Austria : 1996) 1997;104(4-5):399-417.
1997: Nathalie Griffon; C Pilon; F Sautel; Jean-Charles Schwartz; Pierre Sokoloff
Two intracellular signaling pathways for the dopamine D3 receptor: opposite and synergistic interactions with cyclic AMP.
Journal of neurochemistry 1997;68(1):1-9.
1996: V Dimitriadou; Agnès Rouleau; M D Tuong; Xavier Ligneau; G F Newlands; Hugh Miller; Jean-Charles Schwartz; Monique Garbarg
Rat cerebral mast cells undergo phenotypic changes during development.
Brain research. Developmental brain research 1996;97(1):29-41.
1996: S Morisset; Elisabeth Traiffort; Jean-Charles Schwartz
Inhibition of histamine versus acetylcholine metabolism as a mechanism of tacrine activity.
European journal of pharmacology 1996;315(1):R1-2.
1996: Michael Krause; Agnès Rouleau; Holger Stark; Monique Garbarg; Jean-Charles Schwartz; Walter Schunack
Structure-activity relationships of novel azomethine prodrugs of the histamine H3-receptor agonist (R)-alpha-methylhistamine: from alkylaryl to substituted diaryl derivatives.
Die Pharmazie 1996;51(10):720-6.
1996: C Robin Ganellin; A Fkyerat; B Bang-Andersen; S Athmani; W Tertiuk; Monique Garbarg; Xavier Ligneau; Jean-Charles Schwartz
A novel series of (phenoxyalkyl)imidazoles as potent H3-receptor histamine antagonists.
Journal of medicinal chemistry 1996;39(19):3806-13.
1996: A Buvry; Monique Garbarg; V Dimitriadou; Agnès Rouleau; G F Newlands; R Tavakoli; V Poaty; A Lockhart; Jean-Charles Schwartz; Nelly Frossard
Phenotypic and quantitative changes in mast cells after syngeneic unilateral lung transplantation in the rat.
Clinical science (London, England : 1979) 1996;91(3):319-27.
1996: G Drutel; M Kathmann; A Heron; Jean-Charles Schwartz; Jean-Michel Arrang
Cloning and selective expression in brain and kidney of ARNT2 homologous to the Ah receptor nuclear translocator (ARNT).
Biochemical and biophysical research communications 1996;225(2):333-9.
1996: Annette Hüls; K Purand; Holger Stark; S Reidemeister; Xavier Ligneau; Jean-Michel Arrang; Jean-Charles Schwartz; Walter Schunack
Novel histamine H3-receptor antagonists with benzyl ether structure or related moieties: synthesis and structure-activity relationships.
Archiv der Pharmazie 1996;329(8-9):379-85.
1996: A Héron; Elisabeth Traiffort; M Allix; V Dimitriadou; Jean-Charles Schwartz
Prodynorphin mRNA expression in the rat dentate gyrus after cerebral ischemia.
Neuropeptides 1996;30(4):355-8.
1996: C Rose; F Vargas; P Facchinetti; P Bourgeat; R B Bambal; P B Bishop; S M Chan; A N Moore; C R Ganellin; Jean-Charles Schwartz
Characterization and inhibition of a cholecystokinin-inactivating serine peptidase.
Nature 1996;380(6573):403-9.
1996: Michael Krause; Agnès Rouleau; Holger Stark; P Luger; Monique Garbarg; Jean-Charles Schwartz; Walter Schunack
New potent azomethine prodrugs of the histamine H3-receptor agonist (R)-alpha-methylhistamine containing a heteroarylphenyl partial structure.
Archiv der Pharmazie 1996;329(4):209-15.
1996: Holger Stark; K Purand; Annette Hüls; Xavier Ligneau; Monique Garbarg; Jean-Charles Schwartz; Walter Schunack
[125I]iodoproxyfan and related compounds: a reversible radioligand and novel classes of antagonists with high affinity and selectivity for the histamine H3 receptor.
Journal of medicinal chemistry 1996;39(6):1220-6.
1996: Holger Stark; K Purand; Xavier Ligneau; Agnès Rouleau; Jean-Michel Arrang; Monique Garbarg; Jean-Charles Schwartz; Walter Schunack
Novel carbamates as potent histamine H3 receptor antagonists with high in vitro and oral in vivo activity.
Journal of medicinal chemistry 1996;39(5):1157-63.
1996: Nathalie Griffon; Marc-Antoine Crocq; C Pilon; M P Martres; A Mayerova; G Uyanik; Edgar Burgert; Fabrice Duval; Jean-Paul Macher; France Javoy-Agid; Carol A Tamminga; Jean-Charles Schwartz; Pierre Sokoloff
Dopamine D3 receptor gene: organization, transcript variants, and polymorphism associated with schizophrenia.
American journal of medical genetics 1996;67(1):63-70.
1996: E Normant; Jean-Charles Schwartz; C Gros
A novel [125I]iodinated carboxypeptidase A substrate detects a metallopeptidase activity distinct from carboxypeptidase A in brain.
Neuropeptides 1996;30(1):13-7.
1996: Nathalie Griffon; F Sautel; C Pilon; D Lévesque; Pierre Sokoloff; Jean-Charles Schwartz; Jorge Diaz; P Simon; J Costentin; A Mann; C G Wermuth
Functional models for the dopamine D3 receptor.
Biochemical Society transactions 1996;24(1):193-8.
1996: Nathalie Griffon; C Pilon; F Sautel; Jean-Charles Schwartz; Pierre Sokoloff
Antipsychotics with inverse agonist activity at the dopamine D3 receptor.
Journal of neural transmission (Vienna, Austria : 1996) 1996;103(10):1163-75.
1995: E Normant; M P Martres; Jean-Charles Schwartz; C Gros
Purification, cDNA cloning, functional expression, and characterization of a 26-kDa endogenous mammalian carboxypeptidase inhibitor.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(26):12225-9.
1995: F Sautel; Nathalie Griffon; Pierre Sokoloff; Jean-Charles Schwartz; C Launay; P Simon; J Costentin; A Schoenfelder; F Garrido; A Mann
Nafadotride, a potent preferential dopamine D3 receptor antagonist, activates locomotion in rodents.
The Journal of pharmacology and experimental therapeutics 1995;275(3):1239-46.
1995: Jean-Charles Schwartz; Nathalie Griffon; Jorge Diaz; D Levesque; F Sautel; Pierre Sokoloff; P Simon; J Costentin; F Garrido; A Mann
The D3 receptor and its relevance in psychiatry.
International clinical psychopharmacology 1995;10 Suppl 3():15-20.
1995: E Normant; C Gros; Jean-Charles Schwartz
Carboxypeptidase A isoforms produced by distinct genes or alternative splicing in brain and other extrapancreatic tissues.
The Journal of biological chemistry 1995;270(35):20543-9.
1995: Nathalie Griffon; C Pilon; Jean-Charles Schwartz; Pierre Sokoloff
The preferential dopamine D3 receptor ligand, (+)-UH232, is a partial agonist.
European journal of pharmacology 1995;282(1-3):R3-4.
1995: C Robin Ganellin; S K Hosseini; Y S Khalaf; W Tertiuk; Jean-Michel Arrang; Monique Garbarg; Xavier Ligneau; Jean-Charles Schwartz
Design of potent non-thiourea H3-receptor histamine antagonists.
Journal of medicinal chemistry 1995;38(17):3342-50.
1995: Pierre Sokoloff; Jean-Charles Schwartz
Novel dopamine receptors half a decade later.
Trends in pharmacological sciences 1995;16(8):270-5.
1995: Elisabeth Traiffort; Marisa Vizuete; Joël Tardivel-Lacombe; Evelyne Souil; Jean-Charles Schwartz; Martial Ruat
The guinea pig histamine H2 receptor: gene cloning, tissue expression and chromosomal localization of its human counterpart.
Biochemical and biophysical research communications 1995;211(2):570-7.
1995: Jean-Michel Arrang; G Drutel; Monique Garbarg; Martial Ruat; Elisabeth Traiffort; Jean-Charles Schwartz
Molecular and functional diversity of histamine receptor subtypes.
Annals of the New York Academy of Sciences 1995;757():314-23.
1995: Pierre Sokoloff; Jorge Diaz; D Levesque; C Pilon; V Dimitriadou; Nathalie Griffon; Claas-Hinrich Lammers; M P Martres; Jean-Charles Schwartz
Novel dopamine receptor subtypes as targets for antipsychotic drugs.
Annals of the New York Academy of Sciences 1995;757():278-92.
1995: Marisa Vizuete; V Dimitriadou; Elisabeth Traiffort; Nathalie Griffon; A Heron; Jean-Charles Schwartz
Endogenous histamine induces c-fos expression within paraventricular and supraoptic nuclei.
Neuroreport 1995;6(7):1041-4.
1995: K Kieć-Kononowicz; Xavier Ligneau; Jean-Charles Schwartz; Walter Schunack
Pyrazoles as potential histamine H3-receptor antagonists.
Archiv der Pharmazie 1995;328(5):469-72.
1995: K Kieć-Kononowicz; Xavier Ligneau; Holger Stark; Jean-Charles Schwartz; Walter Schunack
Azines and diazines as potential histamine H3-receptor antagonists.
Archiv der Pharmazie 1995;328(5):445-50.
1995: Jorge Diaz; D Lévesque; Claas-Hinrich Lammers; Nathalie Griffon; M P Martres; Jean-Charles Schwartz; Pierre Sokoloff
Phenotypical characterization of neurons expressing the dopamine D3 receptor in the rat brain.
Neuroscience 1995;65(3):731-45.
1995: Jean-Michel Arrang; G Drutel; Jean-Charles Schwartz
Characterization of histamine H3 receptors regulating acetylcholine release in rat entorhinal cortex.
British journal of pharmacology 1995;114(7):1518-22.
1995: C Rose; F Vargas; B Silhouette; B Devaux; Jean-Charles Schwartz
Characterization of a serine peptidase responsible for the inactivation of endogenous cholecystokinin in human brain.
Neuropeptides 1995;28(3):157-60.
1995: C Robin Ganellin; A Fkyerat; S K Hosseini; Y S Khalaf; A Piripitsi; W Tertiuk; Jean-Michel Arrang; Monique Garbarg; Xavier Ligneau; Jean-Charles Schwartz
Structure-activity studies with histamine H3-receptor ligands.
Journal de pharmacie de Belgique 1995;50(2-3):179-87.
1995: D Lévesque; M P Martres; Jorge Diaz; Nathalie Griffon; Claas-Hinrich Lammers; Pierre Sokoloff; Jean-Charles Schwartz
A paradoxical regulation of the dopamine D3 receptor expression suggests the involvement of an anterograde factor from dopamine neurons.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(5):1719-23.
1995: F Sautel; Nathalie Griffon; D Lévesque; C Pilon; Jean-Charles Schwartz; Pierre Sokoloff
A functional test identifies dopamine agonists selective for D3 versus D2 receptors.
Neuroreport 1995;6(2):329-32.
1995: Nathalie Griffon; Pierre Sokoloff; Jorge Diaz; D Lévesque; F Sautel; Jean-Charles Schwartz; P Simon; J Costentin; F Garrido; A Mann
The dopamine D3 receptor and schizophrenia: pharmacological, anatomical and genetic approaches.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 1995;5 Suppl():3-9.
1995: G Drutel; Jean-Michel Arrang; J Diaz; C Wisnewsky; K Schwartz; Jean-Charles Schwartz
Cloning of OL1, a putative olfactory receptor and its expression in the developing rat heart.
Receptors & channels 1995;3(1):33-40.
1994: Vincenzo Di Marzo; A Fontana; H Cadas; S Schinelli; G Cimino; Jean-Charles Schwartz; Daniele Piomelli
Formation and inactivation of endogenous cannabinoid anandamide in central neurons.
Nature 1994;372(6507):686-91.
1994: Xavier Ligneau; Monique Garbarg; Marisa Vizuete; Jorge Diaz; K Purand; Holger Stark; Walter Schunack; Jean-Charles Schwartz
[125I]iodoproxyfan, a new antagonist to label and visualize cerebral histamine H3 receptors.
The Journal of pharmacology and experimental therapeutics 1994;271(1):452-9.
1994: Jorge Diaz; D Lévesque; Nathalie Griffon; Claas-Hinrich Lammers; M P Martres; Pierre Sokoloff; Jean-Charles Schwartz
Opposing roles for dopamine D2 and D3 receptors on neurotensin mRNA expression in nucleus accumbens.
The European journal of neuroscience 1994;6(8):1384-7.
1994: V Dimitriadou; Agnès Rouleau; M Dam Trung Tuong; G J Newlands; Hugh Miller; G Luffau; Jean-Charles Schwartz; Monique Garbarg
Functional relationship between mast cells and C-sensitive nerve fibres evidenced by histamine H3-receptor modulation in rat lung and spleen.
Clinical science (London, England : 1979) 1994;87(2):151-63.
1994: Agnès Rouleau; M D Tuong; G F Newlands; Hugh Miller; Jean-Charles Schwartz; Monique Garbarg
Fasting or dexamethasone treatment reduce protease content in rat lung mast cells and modulation of histamine synthesis by H3 receptors.
Agents and actions 1994;42(1-2):7-12.
1994: C Pilon; D Lévesque; V Dimitriadou; Nathalie Griffon; M P Martres; Jean-Charles Schwartz; Pierre Sokoloff
Functional coupling of the human dopamine D3 receptor in a transfected NG 108-15 neuroblastoma-glioma hybrid cell line.
European journal of pharmacology 1994;268(2):129-39.
1994: Nathalie Griffon; V Mignon; P Facchinetti; Jorge Diaz; Jean-Charles Schwartz; Pierre Sokoloff
Molecular cloning and characterization of the rat fifth melanocortin receptor.
Biochemical and biophysical research communications 1994;200(2):1007-14.
1994: Agnès Rouleau; Monique Garbarg; Jean-Charles Schwartz; Martial Ruat
Molecular cloning of rat mast cell protease 1 and development of specific probes for its gene transcript.
Biochemical and biophysical research communications 1994;199(2):593-602.
1994: Jorge Diaz; Marisa Vizuete; Elisabeth Traiffort; Jean-Michel Arrang; Martial Ruat; Jean-Charles Schwartz
Localization of the histamine H2 receptor and gene transcripts in rat stomach: back to parietal cells.
Biochemical and biophysical research communications 1994;198(3):1195-202.
1994: R Leurs; Elisabeth Traiffort; Jean-Michel Arrang; Joël Tardivel-Lacombe; Martial Ruat; Jean-Charles Schwartz
Guinea pig histamine H1 receptor. II. Stable expression in Chinese hamster ovary cells reveals the interaction with three major signal transduction pathways.
Journal of neurochemistry 1994;62(2):519-27.
1994: Elisabeth Traiffort; R Leurs; Jean-Michel Arrang; Joël Tardivel-Lacombe; Jorge Diaz; Jean-Charles Schwartz; Martial Ruat
Guinea pig histamine H1 receptor. I. Gene cloning, characterization, and tissue expression revealed by in situ hybridization.
Journal of neurochemistry 1994;62(2):507-18.
1994: C Gros; Jean-Charles Schwartz; P L Duhamel; JM Lecomte; J Bralet
"Atriopeptidase" (EC 3.4.24.11) inhibition and protection of atrial natriuretic factor.
Advances in nephrology from the Necker Hospital 1994;23():233-46.
1994: Jean-Charles Schwartz; Jorge Diaz; Nathalie Griffon; D Levesque; M P Martres; Pierre Sokoloff
Multiple dopamine receptors: the D3 receptor and actions of substances of abuse.
EXS 1994;71():81-92.
1993: Martial Ruat; Elisabeth Traiffort; R Leurs; Joël Tardivel-Lacombe; Jorge Diaz; Jean-Michel Arrang; Jean-Charles Schwartz
Molecular cloning, characterization, and localization of a high-affinity serotonin receptor (5-HT7) activating cAMP formation.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(18):8547-51.
1993: Jean-Charles Schwartz; D Levesque; M P Martres; Pierre Sokoloff
Dopamine D3 receptor: basic and clinical aspects.
Clinical neuropharmacology 1993;16(4):295-314.
1993: Martial Ruat; Elisabeth Traiffort; Jean-Michel Arrang; Joël Tardivel-Lacombe; Jorge Diaz; R Leurs; Jean-Charles Schwartz
A novel rat serotonin (5-HT6) receptor: molecular cloning, localization and stimulation of cAMP accumulation.
Biochemical and biophysical research communications 1993;193(1):268-76.
1993: H Pollard; J Moreau; J M Arrang; Jean-Charles Schwartz
A detailed autoradiographic mapping of histamine H3 receptors in rat brain areas.
Neuroscience 1993;52(1):169-89.
1993: Monique Garbarg; Jean-Charles Schwartz
The histamine H3 receptor: pharmacology and potential therapeutic applications.
Annales françaises d'anesthèsie et de rèanimation 1993;12(2):114-5.
1993: Bruno GIROS; Pierre Sokoloff; M P Martres; Lars Lannfelt; M Andrieux; R Besançon; C Pilon; M L Bouthenet; Evelyne Souil; Jean-Charles Schwartz
The third dopamine receptor (D3): new perspectives in therapeutics.
Psychopharmacology series 1993;10():82-93.
1992: Marc-Antoine Crocq; R Mant; Philip Asherson; Julie Williams; Y Hode; A Mayerova; David Collier; Lars Lannfelt; Pierre Sokoloff; Jean-Charles Schwartz
Association between schizophrenia and homozygosity at the dopamine D3 receptor gene.
Journal of medical genetics 1992;29(12):858-60.
1992: R Lipp; Jean-Michel Arrang; Monique Garbarg; P Luger; Jean-Charles Schwartz; Walter Schunack
Synthesis, absolute configuration, stereoselectivity, and receptor selectivity of (alpha R, beta S)-alpha,beta-dimethylhistamine, a novel high potent histamine H3 receptor agonist.
Journal of medicinal chemistry 1992;35(23):4434-41.
1992: Monique Garbarg; Jean-Michel Arrang; Agnès Rouleau; Xavier Ligneau; M D Tuong; Jean-Charles Schwartz; C Robin Ganellin
S-[2-(4-imidazolyl)ethyl]isothiourea, a highly specific and potent histamine H3 receptor agonist.
The Journal of pharmacology and experimental therapeutics 1992;263(1):304-10.
1992: D Lévesque; Jorge Diaz; C Pilon; M P Martres; Bruno GIROS; Evelyne Souil; D Schott; J L Morgat; Jean-Charles Schwartz; Pierre Sokoloff
Identification, characterization, and localization of the dopamine D3 receptor in rat brain using 7-[3H]hydroxy-N,N-di-n-propyl-2-aminotetralin.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(17):8155-9.
1992: Elisabeth Traiffort; H Pollard; J Moreau; Martial Ruat; Jean-Charles Schwartz; M I Martinez-Mir; J M Palacios
Pharmacological characterization and autoradiographic localization of histamine H2 receptors in human brain identified with [125I]iodoaminopotentidine.
Journal of neurochemistry 1992;59(1):290-9.
1992: J Hirschfeld; A Buschauer; Sigurd Elz; Walter Schunack; Martial Ruat; Elisabeth Traiffort; Jean-Charles Schwartz
Iodoaminopotentidine and related compounds: a new class of ligands with high affinity and selectivity for the histamine H2 receptor.
Journal of medicinal chemistry 1992;35(12):2231-8.
1992: Pierre Sokoloff; M Andrieux; R Besançon; C Pilon; M P Martres; Bruno GIROS; Jean-Charles Schwartz
Pharmacology of human dopamine D3 receptor expressed in a mammalian cell line: comparison with D2 receptor.
European journal of pharmacology 1992;225(4):331-7.
1992: Elisabeth Traiffort; Martial Ruat; Jean-Michel Arrang; R Leurs; Daniele Piomelli; Jean-Charles Schwartz
Expression of a cloned rat histamine H2 receptor mediating inhibition of arachidonate release and activation of cAMP accumulation.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(7):2649-53.
1992: A Souque; C Gros; Jean-Charles Schwartz
Binding of [125I]atrial natriuretic factor to mouse lung membranes in vivo: characterization and effects of peptidase inhibitors.
The Journal of pharmacology and experimental therapeutics 1992;260(3):1373-8.
1992: Pierre Sokoloff; M P Martres; Bruno GIROS; M L Bouthenet; Jean-Charles Schwartz
Heterogeneity and regulation of central dopamine receptor subtypes studied by cDNA cloning methodology.
Neurochemistry international 1992;20 Suppl():27S-32S.
1992: Pierre Sokoloff; M P Martres; Bruno GIROS; M L Bouthenet; Jean-Charles Schwartz
The third dopamine receptor (D3) as a novel target for antipsychotics.
Biochemical pharmacology 1992;43(4):659-66.
1992: Pierre Sokoloff; Bruno GIROS; M P Martres; M Andrieux; R Besancon; C Pilon; M L Bouthenet; Evelyne Souil; Jean-Charles Schwartz
Localization and function of the D3 dopamine receptor.
Arzneimittel-Forschung 1992;42(2A):224-30.
1992: M P Martres; Pierre Sokoloff; Bruno GIROS; M L Bouthenet; C Pilon; Lars Lannfelt; Jean-Charles Schwartz
[Dopaminergic receptors, multiple targets for neuroleptics].
Annales médico-psychologiques 1992;150(2-3):119-23.
1992: M P Martres; Pierre Sokoloff; Bruno GIROS; Jean-Charles Schwartz
Effects of dopaminergic transmission interruption on the D2 receptor isoforms in various cerebral tissues.
Journal of neurochemistry 1992;58(2):673-9.
1992: Martial Ruat; Elisabeth Traiffort; Monique Garbarg; Jean-Charles Schwartz; P Demonchaux; R J Ife; W Tertiuk; C Robin Ganellin
Design of an affinity matrix for purification of the histamine H1 receptor from guinea pig cerebellum.
Journal of neurochemistry 1992;58(1):350-6.
1992: Martial Ruat; Elisabeth Traiffort; R Leurs; Jean-Michel Arrang; G Kouyoumdjian; Joël Tardivel-Lacombe; Daniele Piomelli; G Diaz; Jean-Charles Schwartz
Molecular biology and pharmacology of histamine receptor subtypes.
Clinical neuropharmacology 1992;15 Suppl 1 Pt A():149A-150A.
1992: Jean-Charles Schwartz
Multiple dopamine receptors: functional implications.
Clinical neuropharmacology 1992;15 Suppl 1 Pt A():1A-2A.
1992: Pierre Sokoloff; D Levesque; M P Martres; Lars Lannfelt; G Diaz; C Pilon; Jean-Charles Schwartz
The dopamine D3 receptor as a key target for antipsychotics.
Clinical neuropharmacology 1992;15 Suppl 1 Pt A():456A-457A.
1991: M L Bouthenet; Evelyne Souil; M P Martres; Pierre Sokoloff; Bruno GIROS; Jean-Charles Schwartz
Localization of dopamine D3 receptor mRNA in the rat brain using in situ hybridization histochemistry: comparison with dopamine D2 receptor mRNA.
Brain research 1991;564(2):203-19.
1991: Martial Ruat; Elisabeth Traiffort; Jean-Michel Arrang; R Leurs; Jean-Charles Schwartz
Cloning and tissue expression of a rat histamine H2-receptor gene.
Biochemical and biophysical research communications 1991;179(3):1470-8.
1991: Daniele Piomelli; C Pilon; Bruno GIROS; Pierre Sokoloff; M P Martres; Jean-Charles Schwartz
Dopamine activation of the arachidonic acid cascade as a basis for D1/D2 receptor synergism.
Nature 1991;353(6340):164-7.
1991: Jean-Michel Arrang; C Gulat-Marnay; N Defontaine; Jean-Charles Schwartz
Regulation of histamine release in rat hypothalamus and hippocampus by presynaptic galanin receptors.
Peptides 1991;12(5):1113-7.
1991: Elisabeth Traiffort; Martial Ruat; Jean-Charles Schwartz
Interaction of mianserin, amitriptyline and haloperidol with guinea pig cerebral histamine H2 receptors studied with [125I]iodoaminopotentidine.
European journal of pharmacology 1991;207(2):143-8.
1991: C Gros; N Noël; A Souque; Jean-Charles Schwartz; D Danvy; J C Plaquevent; L Duhamel; P Duhamel; JM Lecomte; J Bralet
Mixed inhibitors of angiotensin-converting enzyme (EC 3.4.15.1) and enkephalinase (EC 3.4.24.11): rational design, properties, and potential cardiovascular applications of glycopril and alatriopril.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(10):4210-4.
1991: F Hartmann; Marie-France Poirier; Marie-Chantal Bourdel; Henri Loo; J M Lecomte; Jean-Charles Schwartz
Comparison of acetorphan with clonidine for opiate withdrawal symptoms.
The American journal of psychiatry 1991;148(5):627-9.
1991: Catherine Llorens-Cortes; S Zini; C Gros; Jean-Charles Schwartz
Dopaminergic regulation of enkephalin release.
Journal of neurochemistry 1991;56(4):1368-75.
1991: R Lipp; Jean-Michel Arrang; J Buschmann; Monique Garbarg; P Luger; Walter Schunack; Jean-Charles Schwartz
Novel chiral H3-receptor agonists.
Agents and actions. Supplements 1991;33():277-82.
1991: Martial Ruat; Elisabeth Traiffort; M L Bouthenet; Evelyne Souil; H Pollard; J Moreau; Jean-Charles Schwartz; I Martinez-Mir; J M Palacios; J Hirschfeld
Reversible and irreversible labelling of H1- and H2 -receptors using novel [125I] probes.
Agents and actions. Supplements 1991;33():123-44.
1991: Jean-Michel Arrang; Monique Garbarg; Jean-Charles Schwartz; R Lipp; Holger Stark; Walter Schunack; JM Lecomte
The histamine H3-receptor: pharmacology, roles and clinical implications studied with agonists.
Agents and actions. Supplements 1991;33():55-67.
1990: C Llorens-Cortes; Bruno GIROS; Jean-Charles Schwartz
A novel potential metallopeptidase derived from the enkephalinase gene by alternative splicing.
Journal of neurochemistry 1990;55(6):2146-8.
1990: Pierre Sokoloff; Bruno GIROS; M P Martres; M L Bouthenet; Jean-Charles Schwartz
Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics.
Nature 1990;347(6289):146-51.
1990: M I Martinez-Mir; H Pollard; J Moreau; Jean-Michel Arrang; Martial Ruat; Elisabeth Traiffort; Jean-Charles Schwartz; J M Palacios
Three histamine receptors (H1, H2 and H3) visualized in the brain of human and non-human primates.
Brain research 1990;526(2):322-7.
1990: C Gros; A Souque; Jean-Charles Schwartz
Degradation of atrial natriuretic factor in mouse blood in vitro and in vivo: role of enkephalinase (EC 3.4.24.11).
Neuropeptides 1990;17(1):1-5.
1990: Martial Ruat; M L Bouthenet; Jean-Charles Schwartz; C Robin Ganellin
Histamine H1-receptor in heart: unique electrophoretic mobility and autoradiographic localization.
Journal of neurochemistry 1990;55(2):379-85.
1990: Catherine Llorens-Cortes; J G Van Amsterdam; Bruno GIROS; T T Quach; Jean-Charles Schwartz
Enkephalin biosynthesis and release in mouse striatum are inhibited by GABA receptor stimulation: compared changes in preproenkephalin mRNA and Tyr-Gly-Gly levels.
Brain research. Molecular brain research 1990;8(3):227-33.
1990: C Gulat-Marnay; A Lafitte; Jean-Michel Arrang; Jean-Charles Schwartz
Modulation of histamine release in the rat brain by kappa-opioid receptors.
Journal of neurochemistry 1990;55(1):47-53.
1990: Jean-Michel Arrang; J Roy; J L Morgat; Walter Schunack; Jean-Charles Schwartz
Histamine H3 receptor binding sites in rat brain membranes: modulations by guanine nucleotides and divalent cations.
European journal of pharmacology 1990;188(4-5):219-27.
1990: C Gros; A Souque; Jean-Charles Schwartz
Inactivation of atrial natriuretic factor in mice in vivo: crucial role of enkephalinase (EC 3.4.24.11).
European journal of pharmacology 1990;179(1-2):45-56.
1990: Jean-Charles Schwartz; Jean-Michel Arrang; Monique Garbarg; H Pollard
Plenary lecture. A third histamine receptor subtype: characterisation, localisation and functions of the H3-receptor.
Agents and actions 1990;30(1-2):13-23.
1990: Martial Ruat; Elisabeth Traiffort; M L Bouthenet; Jean-Charles Schwartz; J Hirschfeld; A Buschauer; Walter Schunack
Reversible and irreversible labeling and autoradiographic localization of the cerebral histamine H2 receptor using [125I]iodinated probes.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(5):1658-62.
1990: Catherine Llorens-Cortes; Bruno GIROS; T T Quach; Jean-Charles Schwartz
Adaptative changes in two indices of enkephalin neuron activity in mouse striatum following GABAergic stimulation.
Progress in clinical and biological research 1990;328():203-6.
1990: Jean-Charles Schwartz; C Gros; JM Lecomte; J Bralet
Enkephalinase (EC 3.4.24.11) inhibitors: protection of endogenous ANF against inactivation and potential therapeutic applications.
Life sciences 1990;47(15):1279-97.
1990: Jean-Charles Schwartz; Jean-Michel Arrang; M Garbarg; C Gulat-Marnay; H Pollard
Modulation of histamine synthesis and release in brain via presynaptic autoreceptors and heteroreceptors.
Annals of the New York Academy of Sciences 1990;604():40-54.
1989: Bruno GIROS; Pierre Sokoloff; M P Martres; J F Riou; L J Emorine; Jean-Charles Schwartz
Alternative splicing directs the expression of two D2 dopamine receptor isoforms.
Nature 1989;342(6252):923-6.
1989: Monique Garbarg; H Pollard; M D Trung Tuong; Jean-Charles Schwartz; C Gros
Sensitive radioimmunoassays for histamine and tele-methylhistamine in the brain.
Journal of neurochemistry 1989;53(6):1724-30.
1989: C Gros; A Souque; Jean-Charles Schwartz; J Duchier; A Cournot; Philippe Baumer; JM Lecomte
Protection of atrial natriuretic factor against degradation: diuretic and natriuretic responses after in vivo inhibition of enkephalinase (EC 3.4.24.11) by acetorphan.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(19):7580-4.
1989: Martial Ruat; Jean-Charles Schwartz
Photoaffinity labeling and electrophoretic identification of the H1-receptor: comparison of several brain regions and animal species.
Journal of neurochemistry 1989;53(2):335-9.
1989: C Gulat-Marnay; A Lafitte; Jean-Michel Arrang; Jean-Charles Schwartz
Modulation of histamine release and synthesis in the brain mediated by alpha 2-adrenoceptors.
Journal of neurochemistry 1989;53(2):513-8.
1989: Pierre Sokoloff; J F Riou; M P Martres; Jean-Charles Schwartz
Presence of dopamine D-2 receptors in human tumoral cell lines.
Biochemical and biophysical research communications 1989;162(2):575-82.
1989: Monique Garbarg; M D Tuong; C Gros; Jean-Charles Schwartz
Effects of histamine H3-receptor ligands on various biochemical indices of histaminergic neuron activity in rat brain.
European journal of pharmacology 1989;164(1):1-11.
1989: Catherine Llorens-Cortes; M P Martres; Y Van Amsterdam; Bruno GIROS; C Gros; H Pollard; Jean-Charles Schwartz
[Dopamine and enkephalins. Effects of dopaminergic agents on the levels of striatal tyrosyl-glycyl-glycine].
L'Encéphale 1989;15 Spec No():105-9.
1989: C Rose; A Camus; Jean-Charles Schwartz
Protection by serine peptidase inhibitors of endogenous cholecystokinin released from brain slices.
Neuroscience 1989;29(3):583-94.
1989: Jean-Michel Arrang; Monique Garbarg; Jean-Charles Lancelot; JM Lecomte; H Pollard; M Robba; W Schunack; Jean-Charles Schwartz
The third histamine receptor. Highly potent and selective ligands.
International archives of allergy and applied immunology 1989;88(1-2):79-81.
1989: Jean-Charles Schwartz; Jean-Michel Arrang; Monique Garbarg; H Pollard
Histamine H3 receptors in the brain: potent and selective ligands.
Psychopharmacology series 1989;7():10-9.
1989: A Camus; C Rose; Jean-Charles Schwartz
Role of a serine endopeptidase in the hydrolysis of exogenous cholecystokinin by brain slices.
Neuroscience 1989;29(3):595-602.
1989: N Sales; M P Martres; M L Bouthenet; Jean-Charles Schwartz
Ontogeny of dopaminergic D-2 receptors in the rat nervous system: characterization and detailed autoradiographic mapping with [125I]iodosulpride.
Neuroscience 1989;28(3):673-700.
1989: H Pollard; M L Bouthenet; J Moreau; Evelyne Souil; P Verroust; P Ronco; Jean-Charles Schwartz
Detailed immunoautoradiographic mapping of enkephalinase (EC 3.4.24.11) in rat central nervous system: comparison with enkephalins and substance P.
Neuroscience 1989;30(2):339-76.
1989: C Gulat-Marnay; A Lafitte; Jean-Michel Arrang; Jean-Charles Schwartz
Regulation of histamine release and synthesis in the brain by muscarinic receptors.
Journal of neurochemistry 1989;52(1):248-54.
1988: Jean-Michel Arrang; N Defontaine; Jean-Charles Schwartz
Phencyclidine blocks histamine H3-receptors in rat brain.
European journal of pharmacology 1988;157(1):31-5.
1988: S De la Baume; F Brion; M Dam Trung Tuong; Jean-Charles Schwartz
Evaluation of enkephalinase inhibition in the living mouse, using [3H]acetorphan as a probe.
The Journal of pharmacology and experimental therapeutics 1988;247(2):653-60.
1988: Jean-Michel Arrang; Monique Garbarg; Jean-Charles Lancelot; JM Lecomte; H Pollard; M Robba; W Schunack; Jean-Charles Schwartz
[Potential interest in powerful and specific ligands for the histamine H3 receptor].
Allergie et immunologie 1988;20(9):327-9, 331.
1988: C Gros; Bruno GIROS; Jean-Charles Schwartz; A Vlaiculescu; J Costentin; JM Lecomte
Potent inhibition of cerebral aminopeptidases by carbaphethiol, a parenterally active compound.
Neuropeptides 1988;12(3):111-8.
1988: Jean-Michel Arrang; Monique Garbarg; Jean-Charles Lancelot; JM Lecomte; H Pollard; M Robba; W Schunack; Jean-Charles Schwartz
Highly potent and selective ligands for a new class H3 of histamine receptor.
Investigative radiology 1988;23 Suppl 1():S130-2.
1988: M L Bouthenet; Martial Ruat; N Sales; Monique Garbarg; Jean-Charles Schwartz
A detailed mapping of histamine H1-receptors in guinea-pig central nervous system established by autoradiography with [125I]iodobolpyramine.
Neuroscience 1988;26(2):553-600.
1988: Jean-Michel Arrang; B Devaux; J P Chodkiewicz; Jean-Charles Schwartz
H3-receptors control histamine release in human brain.
Journal of neurochemistry 1988;51(1):105-8.
1988: S De la Baume; Jean-Charles Schwartz
Labelling and exploration of the active site of enkephalinase (EC 3.4.24.11) in kidney membranes with [3H]thiorphan as ligand.
European journal of pharmacology 1988;149(1-2):121-9.
1988: Martial Ruat; M Körner; Monique Garbarg; C Gros; Jean-Charles Schwartz; W Tertiuk; C Robin Ganellin
Characterization of histamine H1-receptor binding peptides in guinea pig brain using [125I]iodoazidophenpyramine, an irreversible specific photoaffinity probe.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(8):2743-7.
1988: Monique Garbarg; Jean-Charles Schwartz
Synergism between histamine H1- and H2-receptors in the cAMP response in guinea pig brain slices: effects of phorbol esters and calcium.
Molecular pharmacology 1988;33(1):38-43.
1987: Bruno GIROS; C Gros; Jean-Charles Schwartz; D Danvy; J C Plaquevent; L Duhamel; P Duhamel; A Vlaiculescu; J Costentin; JM Lecomte
Enantiomers of thiorphan and acetorphan: correlation between enkephalinase inhibition, protection of endogenous enkephalins and behavioral effects.
The Journal of pharmacology and experimental therapeutics 1987;243(2):666-73.
1987: C Gulat-Marnay; A Lafitte; F Vargas; Jean-Charles Schwartz
Formation and utilization of the active sulfate donor [35S]3'-phosphoadenosine 5'-phosphosulfate in brain slices: effects of depolarizing agents.
Journal of neurochemistry 1987;49(5):1443-8.
1987: Jean-Michel Arrang; Monique Garbarg; Jean-Charles Schwartz
Autoinhibition of histamine synthesis mediated by presynaptic H3-receptors.
Neuroscience 1987;23(1):149-57.
1987: B Solhonne; C Gros; H Pollard; Jean-Charles Schwartz
Major localization of aminopeptidase M in rat brain microvessels.
Neuroscience 1987;22(1):225-32.
1987: M L Bouthenet; M P Martres; N Sales; Jean-Charles Schwartz
A detailed mapping of dopamine D-2 receptors in rat central nervous system by autoradiography with [125I]iodosulpride.
Neuroscience 1987;20(1):117-55.
1986: Jean-Charles Schwartz; J M Arrang; Monique Garbarg; M Korner
Properties and roles of the three subclasses of histamine receptors in brain.
The Journal of experimental biology 1986;124():203-24.
1986: JM Lecomte; J Costentin; A Vlaiculescu; P Chaillet; H Marcais-Collado; C Llorens-Cortes; M Leboyer; Jean-Charles Schwartz
Pharmacological properties of acetorphan, a parenterally active "enkephalinase" inhibitor.
The Journal of pharmacology and experimental therapeutics 1986;237(3):937-44.
1986: J Costentin; A Vlaiculescu; P Chaillet; L Ben Natan; D Aveaux; Jean-Charles Schwartz
Dissociated effects of inhibitors of enkephalin-metabolising peptidases or naloxone on various nociceptive responses.
European journal of pharmacology 1986;123(1):37-44.
1986: Bruno GIROS; C Gros; B Solhonne; Jean-Charles Schwartz
Characterization of aminopeptidases responsible for inactivating endogenous (Met5)enkephalin in brain slices using peptidase inhibitors and anti-aminopeptidase M antibodies.
Molecular pharmacology 1986;29(3):281-7.
1986: M Korner; M L Bouthenet; C Robin Ganellin; Monique Garbarg; C Gros; R J Ife; N Sales; Jean-Charles Schwartz
[125I]Iodobolpyramine, a highly sensitive probe for histamine H1-receptors in guinea-pig brain.
European journal of pharmacology 1986;120(2):151-60.
1986: Jean-Charles Schwartz; S de la Baume; M L Bouthenet; Bruno GIROS; C Gros; C Llorens-Cortes; H Pollard; N Sales; B Solhonne; J Costentin
[Neuropeptidases responsible for the inactivation of enkephalins and the pharmacology of their inhibitors].
Journal de pharmacologie 1986;17 Suppl 2():104-22.
1986: F Vargas; M D Tuong; Jean-Charles Schwartz
Inhibitors and dipeptide substrates for a microsomal tyrosylsulfotransferase from rat brain.
Journal of enzyme inhibition 1986;1(2):105-12.
1986: C Llorens-Cortes; C Gros; Jean-Charles Schwartz
Evaluation of striatal enkephalin release in vivo from steady state levels and turnover rates of the tripeptide Tyr-Gly-Gly.
NIDA research monograph 1986;75():275-8.
1986: C Gros; B Solhonne; Bruno GIROS; H Pollard; N Salès; Jean-Charles Schwartz; P Ronco; P Verroust
Immunohistochemical and subcellular studies of aminopeptidase M localization in rat brain: microvessels and synaptic membranes.
NIDA research monograph 1986;75():303-6.
1985: M P Martres; N Sales; M L Bouthenet; Jean-Charles Schwartz
Localisation and pharmacological characterisation of D-2 dopamine receptors in rat cerebral neocortex and cerebellum using [125I]iodosulpride.
European journal of pharmacology 1985;118(3):211-9.
1985: K Redouane; Pierre Sokoloff; Jean-Charles Schwartz; P Hamdi; A Mann; Camille G Wermuth; J Roy; J L Morgat
Photoaffinity labeling of D-2 dopamine binding subunits from rat striatum, anterior pituitary and olfactory bulb with a new probe, [3H]azidosulpride.
Biochemical and biophysical research communications 1985;130(3):1086-92.
1985: M L Bouthenet; N Sales; Jean-Charles Schwartz
Autoradiographic localisation of 3H-apomorphine binding sites in rat brain.
Naunyn-Schmiedeberg's archives of pharmacology 1985;330(1):1-8.
1985: M P Martres; M L Bouthenet; N Sales; Pierre Sokoloff; Jean-Charles Schwartz
Widespread distribution of brain dopamine receptors evidenced with [125I]iodosulpride, a highly selective ligand.
Science (New York, N.Y.) 1985;228(4700):752-5.
1985: Pierre Sokoloff; K Redouane; M Brann; M P Martres; Jean-Charles Schwartz
3H-(-)DO 710 discriminates guanine nucleotide sensitive and insensitive dopamine binding sites.
Naunyn-Schmiedeberg's archives of pharmacology 1985;329(3):236-43.
1985: C Gulat-Marnay; A Lafitte; Jean-Charles Schwartz; P Protais
Effects of discriminant and non-discriminant dopamine antagonists on in vivo accumulation of 3H-N-propyl-norapomorphine in mouse striatum and tuberculum olfactorium.
Naunyn-Schmiedeberg's archives of pharmacology 1985;329(2):117-22.
1985: Pierre Sokoloff; M Brann; K Redouane; M P Martres; Jean-Charles Schwartz; M L Bouthenet; N Sales; A Mann; P Hamdi; Camille G Wermuth
The use of [3H](-)-DO 710 as selective dopaminergic ligand for binding and autoradiographic studies.
European journal of pharmacology 1985;107(2):243-51.
1984: Pierre Sokoloff; M P Martres; M Delandre; K Redouane; Jean-Charles Schwartz
3H-Dopamine binding sites differ in rat striatum and pituitary.
Naunyn-Schmiedeberg's archives of pharmacology 1984;327(3):221-7.
1983: P Chaillet; H Marçais-Collado; J Costentin; C C Yi; S De La Baume; Jean-Charles Schwartz
Inhibition of enkephalin metabolism by, and antinociceptive activity of, bestatin, an aminopeptidase inhibitor.
European journal of pharmacology 1983;86(3-4):329-36.
1983: Jean-Charles Schwartz; S de la Baume; C C Yi; P Chaillet; H Marcais-Collado; J Costentin
Peptidases involved in the inactivation of exogenous and endogenous enkephalins.
Journal of neural transmission. Supplementum 1983;18():235-43.
1983: S de la Baume; C C Yi; Jean-Charles Schwartz; P Chaillet; H Marcais-Collado; J Costentin
Participation of both 'enkephalinase' and aminopeptidase activities in the metabolism of endogenous enkephalins.
Neuroscience 1983;8(1):143-51.
1983: Jean-Charles Schwartz; Catherine Llorens-Cortes; C Rose; T T Quach; H Pollard
Adaptive changes of neurotransmitter receptor mechanisms in the central nervous system.
Progress in brain research 1983;58():117-29.
1982: S de la Baume; C Gros; C C Yi; P Chaillet; H Marcais-Collado; J Costentin; Jean-Charles Schwartz
Selective participation of both "enkephalinase" and aminopeptidase activities in the metabolism of endogenous enkephalins.
Life sciences 1982;31(16-17):1753-6.
1982: Jean-Charles Schwartz; S De La Baume; C C Yi; P Chaillet; H Marcais-Collado; J Costentin
Enkephalin metabolism in brain and its inhibition.
Progress in neuro-psychopharmacology & biological psychiatry 1982;6(4-6):665-71.
1980: M Dam Trung Tuong; Monique Garbarg; Jean-Charles Schwartz
Pharmacological specificity of brain histamine H2-receptors differs in intact cells and cell-free preparations.
Nature 1980;287(5782):548-51.
1980: Jean-Charles Schwartz; H Pollard; T T Quach
Histamine as a neurotransmitter in mammalian brain: neurochemical evidence.
Journal of neurochemistry 1980;35(1):26-33.