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Thue Schwartz

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Thor C Møller; Nina I Roberts; Thue W Schwartz; Kristian Strømgaard; Volker F Wirth; Anders Bach; Julia Bender; Jan M Deussing; Birgitte P S Jacky; Karen L Martinez
PDZ domain-mediated interactions of g protein-coupled receptors with postsynaptic density protein 95: quantitative characterization of interactions.
Jens Pedersen; Steen Seier Poulsen; Thue W Schwartz; Randi Ugleholdt; J A Windeløv; Ernst-Martin Füchtbauer; K V Grunddal; Peter J Holst; S M Jørgensen; Jens Juul Holst
Glucose metabolism is altered after loss of L cells and α-cells but not influenced by loss of K cells.
Louise Valentin-Hansen; Thomas M Frimurer; Birgitte Holst; Thue W Schwartz
PheVI:09 (Phe6.44) as a sliding microswitch in seven-transmembrane (7TM) G protein-coupled receptor activation.

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2013: Thor C Møller; Nina I Roberts; Thue W Schwartz; Kristian Strømgaard; Volker F Wirth; Anders Bach; Julia Bender; Jan M Deussing; Birgitte P S Jacky; Karen L Martinez
PDZ domain-mediated interactions of g protein-coupled receptors with postsynaptic density protein 95: quantitative characterization of interactions.
PloS one 2013;8(5):e63352.
2013: Jens Pedersen; Steen Seier Poulsen; Thue W Schwartz; Randi Ugleholdt; J A Windeløv; Ernst-Martin Füchtbauer; K V Grunddal; Peter J Holst; S M Jørgensen; Jens Juul Holst
Glucose metabolism is altered after loss of L cells and α-cells but not influenced by loss of K cells.
American journal of physiology. Endocrinology and metabolism 2013;304(1):E60-73.
2012: Louise Valentin-Hansen; Thomas M Frimurer; Birgitte Holst; Thue W Schwartz
PheVI:09 (Phe6.44) as a sliding microswitch in seven-transmembrane (7TM) G protein-coupled receptor activation.
The Journal of biological chemistry 2012;287(52):43516-26.
2012: Demet Araç; Gabriela Aust; davide calebiro; Felix B Engel; Caroline Formstone; André Goffinet; Jörg Hamann; Robert J Kittel; Ines Liebscher; Hsi-Hsien Lin; Kelly R Monk; Alexander Petrenko; Xianhua Piao; Simone Prömel; Helgi B Schiöth; Thue W Schwartz; Martin Stacey; Yuri A Ushkaryov; Manja Wobus; Uwe Wolfrum; Lei Xu; Tobias Langenhan
Dissecting signaling and functions of adhesion G protein-coupled receptors.
Annals of the New York Academy of Sciences 2012;1276():1-25.
2012: Kristoffer Lihme Egerod; Maja S Engelstoft; Ernst-Martin Füchtbauer; Kaare V Grunddal; Jens J Holst; Mark K Nøhr; Jørgen Olsen; Jesper V Olsen; Jens Pedersen; Steen S Poulsen; Ichiro Sakata; Anna Secher; Frank Sundler; Nils Wierup; Johanne A Windeløv; Jeffrey M Zigman; Jan P Christensen; Thue W Schwartz
A major lineage of enteroendocrine cells coexpress CCK, secretin, GIP, GLP-1, PYY, and neurotensin but not somatostatin.
Endocrinology 2012;153(12):5782-95.
2012: Jacek Mokrosiński; Thomas M Frimurer; Thue W Schwartz; Bjørn Sivertsen; Birgitte Holst
Modulation of constitutive activity and signaling bias of the ghrelin receptor by conformational constraint in the second extracellular loop.
The Journal of biological chemistry 2012;287(40):33488-502.
2012: Louise Valentin-Hansen; Thomas M Frimurer; Marleen Groenen; Nicholas D Holliday; Rie Nygaard; Thue W Schwartz
The arginine of the DRY motif in transmembrane segment III functions as a balancing micro-switch in the activation of the β2-adrenergic receptor.
The Journal of biological chemistry 2012;287(38):31973-82.
2012: Sylvia Els; Thomas M Frimurer; Birgitte Holst; Tom-Marten Kilian; Jacek Mokrosinski; Pia Steen Petersen; Enrico Schild; Thue W Schwartz; Constance Chollet; Annette G Beck-Sickinger
An aromatic region to induce a switch between agonism and inverse agonism at the ghrelin receptor.
Journal of medicinal chemistry 2012;55(17):7437-49.
2012: Harald S Hansen; Jens J Holst; Mette M Rosenkilde; Thue W Schwartz
GPR119 as a fat sensor.
Trends in pharmacological sciences 2012;33(7):374-81.
2011: Pia Steen Petersen; Maria Rasmussen; Thue W Schwartz; Kristoffer Lihme Egerod; Chunyu Jin; Rune Kuhre; Andreas Nygaard Madsen; Lars B Nielsen; Birgitte Holst
Deficiency of the GPR39 receptor is associated with obesity and altered adipocyte metabolism.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2011;25(11):3803-14.
2011: Thue W Schwartz; Thomas P Sakmar
Structural biology: snapshot of a signalling complex.
Nature 2011;477(7366):540-1.
2011: Tau Benned-Jensen; Andy Blanchard; Peter J Holst; Robert Jepras; Kevin R Page; Howard Sauls; Thue W Schwartz; Bjørn Sivertsen; Christopher Smethurst; Mette M Rosenkilde
Ligand modulation of the Epstein-Barr virus-induced seven-transmembrane receptor EBI2: identification of a potent and efficacious inverse agonist.
The Journal of biological chemistry 2011;286(33):29292-302.
2011: Bjørn Sivertsen; Manja Lang; Thomas M Frimurer; Nicholas D Holliday; Anders Bach; Sylvia Els; Maja S Engelstoft; Pia S Petersen; Andreas N Madsen; Thue W Schwartz; Annette G Beck-Sickinger; Birgitte Holst
Unique interaction pattern for a functionally biased ghrelin receptor agonist.
The Journal of biological chemistry 2011;286(23):20845-60.
2011: Kathrin Bellmann-Sickert; Christian E Elling; Andreas N Madsen; Paul B Little; Karsten Lundgren; Lars-Ole Gerlach; Ralf Bergmann; Birgitte Holst; Thue W Schwartz; Annette G Beck-Sickinger
Long-acting lipidated analogue of human pancreatic polypeptide is slowly released into circulation.
Journal of medicinal chemistry 2011;54(8):2658-67.
2010: Mette M Rosenkilde; Tau Benned-Jensen; Thomas M Frimurer; Thue W Schwartz
The minor binding pocket: a major player in 7TM receptor activation.
Trends in pharmacological sciences 2010;31(12):567-74.
2010: Rie Nygaard; Louise Valentin-Hansen; Jacek Mokrosinski; Thomas M Frimurer; Thue W Schwartz
Conserved water-mediated hydrogen bond network between TM-I, -II, -VI, and -VII in 7TM receptor activation.
The Journal of biological chemistry 2010;285(25):19625-36.
2010: Thue W Schwartz; Birgitte Holst
An enteroendocrine full package solution.
Cell metabolism 2010;11(6):445-7.
2010: Ehm A Andersson; Birgitte Holst; Thomas Sparsø; Niels Grarup; Karina Banasik; Johan Holmkvist; Torben Jørgensen; Knut Borch-Johnsen; Kristoffer Lihme Egerod; Torsten Lauritzen; Thorkild I A Sørensen; Amélie Bonnefond; David Meyre; philippe froguel; Thue W Schwartz; Oluf Pedersen; Torben Hansen
MTNR1B G24E variant associates With BMI and fasting plasma glucose in the general population in studies of 22,142 Europeans.
Diabetes 2010;59(6):1539-48.
2010: Birgitte Holst; Rie Nygaard; Louise Valentin-Hansen; Anders Bach; Maja S Engelstoft; Pia S Petersen; Thomas M Frimurer; Thue W Schwartz
A conserved aromatic lock for the tryptophan rotameric switch in TM-VI of seven-transmembrane receptors.
The Journal of biological chemistry 2010;285(6):3973-85.
2010: Anette P Gjesing; Lesli H Larsen; Signe S Torekov; Irena Aldhoon Hainerová; Rahul Kapur; Anders Johansen; Anders Albrechtsen; Sylvia Boj; Birgitte Holst; Angela Harper; Søren A Urhammer; Knut Borch-Johnsen; Charlotta Pisinger; Søren M Echwald; Hans Eiberg; Arne Astrup; Jan Lebl; Jorge Ferrer; Thue W Schwartz; Torben Hansen; Oluf Pedersen
Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity.
PloS one 2010;5(4):e10084.
2009: Birgitte Holst; Kristoffer Lihme Egerod; Chunyu Jin; Pia Steen Petersen; Mette Viberg Østergaard; Jacob Hald; A M Ejernaes Sprinkel; Joachim Størling; Thomas Mandrup-Poulsen; Jens J Holst; Peter Thams; Cathrine Orskov; Nils Wierup; Frank Sundler; Ole D Madsen; Thue W Schwartz
G protein-coupled receptor 39 deficiency is associated with pancreatic islet dysfunction.
Endocrinology 2009;150(6):2577-85.
2009: Rie Nygaard; Thomas M Frimurer; Birgitte Holst; Mette M Rosenkilde; Thue W Schwartz
Ligand binding and micro-switches in 7TM receptor structures.
Trends in pharmacological sciences 2009;30(5):249-59.
2009: Marie Terpager; D Jason Scholl; Valentina Kubale; Lene Martini; Christian E Elling; Thue W Schwartz
Construction of covalently coupled, concatameric dimers of 7TM receptors.
Journal of receptor and signal transduction research 2009;29(5):235-45.
2008: Maja S Engelstoft; Kristoffer Lihme Egerod; Birgitte Holst; Thue W Schwartz
A gut feeling for obesity: 7TM sensors on enteroendocrine cells.
Cell metabolism 2008;8(6):447-9.
2008: Thue W Schwartz; Wayne L Hubbell
Structural biology: A moving story of receptors.
Nature 2008;455(7212):473-4.
2008: Laura Storjohann; Birgitte Holst; Thue W Schwartz
A second disulfide bridge from the N-terminal domain to extracellular loop 2 dampens receptor activity in GPR39.
Biochemistry 2008;47(35):9198-207.
2008: Pia C Jensen; Stefanie Thiele; Trond Ulven; Thue W Schwartz; Mette M Rosenkilde
Positive versus negative modulation of different endogenous chemokines for CC-chemokine receptor 1 by small molecule agonists through allosteric versus orthosteric binding.
The Journal of biological chemistry 2008;283(34):23121-8.
2008: Laura Storjohann; Birgitte Holst; Thue W Schwartz
Molecular mechanism of Zn2+ agonism in the extracellular domain of GPR39.
FEBS letters 2008;582(17):2583-8.
2008: Rasmus Jorgensen; Nicholas D Holliday; Jakob L Hansen; Milka Vrecl; Anders Heding; Thue W Schwartz; Christian E Elling
Characterization of G-protein coupled receptor kinase interaction with the neurokinin-1 receptor using bioluminescence resonance energy transfer.
Molecular pharmacology 2008;73(2):349-58.
2007: Nicholas D Holliday; Birgitte Holst; Elena A Rodionova; Thue W Schwartz; Helen M Cox
Importance of constitutive activity and arrestin-independent mechanisms for intracellular trafficking of the ghrelin receptor.
Molecular endocrinology (Baltimore, Md.) 2007;21(12):3100-12.
2007: Mette M Rosenkilde; Lars-Ole Gerlach; Sigrid Hatse; Renato T Skerlj; Dominique Schols; Gary J Bridger; Thue W Schwartz
Molecular mechanism of action of monocyclam versus bicyclam non-peptide antagonists in the CXCR4 chemokine receptor.
The Journal of biological chemistry 2007;282(37):27354-65.
2007: Pia C Jensen; Rie Nygaard; Stefanie Thiele; Amy Elder; Guoming Zhu; Roland W Kolbeck; Shomir Ghosh; Thue W Schwartz; Mette M Rosenkilde
Molecular interaction of a potent nonpeptide agonist with the chemokine receptor CCR8.
Molecular pharmacology 2007;72(2):327-40.
2007: Thue W Schwartz; Birgitte Holst
Allosteric enhancers, allosteric agonists and ago-allosteric modulators: where do they bind and how do they act?
Trends in pharmacological sciences 2007;28(8):366-73.
2007: Kristoffer Lihme Egerod; Birgitte Holst; Pia S Petersen; Jacob B Hansen; Jan Mulder; Tomas Hökfelt; Thue W Schwartz
GPR39 splice variants versus antisense gene LYPD1: expression and regulation in gastrointestinal tract, endocrine pancreas, liver, and white adipose tissue.
Molecular endocrinology (Baltimore, Md.) 2007;21(7):1685-98.
2007: Rasmus Jorgensen; Valentina Kubale; Milka Vrecl; Thue W Schwartz; Christian E Elling
Oxyntomodulin differentially affects glucagon-like peptide-1 receptor beta-arrestin recruitment and signaling through Galpha(s).
The Journal of pharmacology and experimental therapeutics 2007;322(1):148-54.
2007: Hans R Lüttichau; Anders H Johnsen; Jesper Jurlander; Mette M Rosenkilde; Thue W Schwartz
Kaposi sarcoma-associated herpes virus targets the lymphotactin receptor with both a broad spectrum antagonist vCCL2 and a highly selective and potent agonist vCCL3.
The Journal of biological chemistry 2007;282(24):17794-805.
2007: Birgitte Holst; Jacek Mokrosinski; Manja Lang; Erik Brandt; Rie Nygaard; Thomas M Frimurer; Annette G Beck-Sickinger; Thue W Schwartz
Identification of an efficacy switch region in the ghrelin receptor responsible for interchange between agonism and inverse agonism.
The Journal of biological chemistry 2007;282(21):15799-811.
2007: Sigrid Hatse; Dana Huskens; Katrien Princen; Kurt Vermeire; Gary J Bridger; Erik De Clercq; Mette M Rosenkilde; Thue W Schwartz; Dominique Schols
Modest human immunodeficiency virus coreceptor function of CXCR3 is strongly enhanced by mimicking the CXCR4 ligand binding pocket in the CXCR3 receptor.
Journal of virology 2007;81(7):3632-9.
2007: Mette M Rosenkilde; Michael B Andersen; Rie Nygaard; Thomas M Frimurer; Thue W Schwartz
Activation of the CXCR3 chemokine receptor through anchoring of a small molecule chelator ligand between TM-III, -IV, and -VI.
Molecular pharmacology 2007;71(3):930-41.
2007: Birgitte Holst; Kristoffer Lihme Egerod; Enrico Schild; Steve P Vickers; Sharon Cheetham; Lars-Ole Gerlach; Laura Storjohann; Carsten E Stidsen; Rob Jones; Annette G Beck-Sickinger; Thue W Schwartz
GPR39 signaling is stimulated by zinc ions but not by obestatin.
Endocrinology 2007;148(1):13-20.
2006: Mette M Rosenkilde; Ralf David; Ilka Oerlecke; Tau Benned-Jensen; Ulf Geumann; Annette G Beck-Sickinger; Thue W Schwartz
Conformational constraining of inactive and active States of a seven transmembrane receptor by metal ion site engineering in the extracellular end of transmembrane segment V.
Molecular pharmacology 2006;70(6):1892-901.
2006: Birgitte Holst; Manja Lang; Erik Brandt; Anders Bach; Andrew Howard; Thomas M Frimurer; Annette G Beck-Sickinger; Thue W Schwartz
Ghrelin receptor inverse agonists: identification of an active peptide core and its interaction epitopes on the receptor.
Molecular pharmacology 2006;70(3):936-46.
2006: Rie Nygaard; Steen Nielbo; Thue W Schwartz; Flemming M Poulsen
The PP-fold solution structure of human polypeptide YY and human PYY3-36 as determined by NMR.
Biochemistry 2006;45(27):8350-7.
2006: Christian E Elling; Thomas M Frimurer; Lars-Ole Gerlach; Rasmus Jorgensen; Birgitte Holst; Thue W Schwartz
Metal ion site engineering indicates a global toggle switch model for seven-transmembrane receptor activation.
The Journal of biological chemistry 2006;281(25):17337-46.
2006: Mette M Rosenkilde; Tau Benned-Jensen; Helene Andersen; Peter J Holst; Thomas N Kledal; Hans R Lüttichau; Jørgen K Larsen; Jan Pravsgaard Christensen; Thue W Schwartz
Molecular pharmacological phenotyping of EBI2. An orphan seven-transmembrane receptor with constitutive activity.
The Journal of biological chemistry 2006;281(19):13199-208.
2006: Birgitte Holst; Thue W Schwartz
Ghrelin receptor mutations--too little height and too much hunger.
The Journal of clinical investigation 2006;116(3):637-41.
2006: Mette M Rosenkilde; Thue W Schwartz
GluVII:06--a highly conserved and selective anchor point for non-peptide ligands in chemokine receptors.
Current topics in medicinal chemistry 2006;6(13):1319-33.
2006: Thue W Schwartz; Birgitte Holst
Ago-allosteric modulation and other types of allostery in dimeric 7TM receptors.
Journal of receptor and signal transduction research 2006;26(1-2):107-28.
2006: Thue W Schwartz; Thomas M Frimurer; Birgitte Holst; Mette M Rosenkilde; Christian E Elling
Molecular mechanism of 7TM receptor activation--a global toggle switch model.
Annual review of pharmacology and toxicology 2006;46():481-519.
2005: Sigrid Hatse; Katrien Princen; Erik De Clercq; Mette M Rosenkilde; Thue W Schwartz; Pedro E Hernandez-Abad; Renato T Skerlj; Gary J Bridger; Dominique Schols
AMD3465, a monomacrocyclic CXCR4 antagonist and potent HIV entry inhibitor.
Biochemical pharmacology 2005;70(5):752-61.
2005: Birgitte Holst; Erik Brandt; Anders Bach; Anders Heding; Thue W Schwartz
Nonpeptide and peptide growth hormone secretagogues act both as ghrelin receptor agonist and as positive or negative allosteric modulators of ghrelin signaling.
Molecular endocrinology (Baltimore, Md.) 2005;19(9):2400-11.
2005: Mette M Rosenkilde; Thomas N Kledal; Thue W Schwartz
High constitutive activity of a virus-encoded seven transmembrane receptor in the absence of the conserved DRY motif (Asp-Arg-Tyr) in transmembrane helix 3.
Molecular pharmacology 2005;68(1):11-9.
2005: Kristian K Jensen; Denise Manfra; Marcos Grisotto; Andrea P Martin; Galya Vassileva; Kevin Kelley; Thue W Schwartz; sergio lira
The human herpes virus 8-encoded chemokine receptor is required for angioproliferation in a murine model of Kaposi's sarcoma.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(6):3686-94.
2005: Rasmus Jorgensen; Lene Martini; Thue W Schwartz; Christian E Elling
Characterization of glucagon-like peptide-1 receptor beta-arrestin 2 interaction: a high-affinity receptor phenotype.
Molecular endocrinology (Baltimore, Md.) 2005;19(3):812-23.
2005: Paola Casarosa; Maria Waldhoer; Patricia J LiWang; Henry Vischer; Thomas N Kledal; Henk Timmerman; Thue W Schwartz; Martine J Smit; Rob Leurs
CC and CX3C chemokines differentially interact with the N terminus of the human cytomegalovirus-encoded US28 receptor.
The Journal of biological chemistry 2005;280(5):3275-85.
2004: Arne Heydorn; Birgitte P Søndergaard; Bjarne K Ersbøll; Birgitte Holst; Omid Niazi; Carol Renfrew Haft; Jennifer L Whistler; Thue W Schwartz
A library of 7TM receptor C-terminal tails. Interactions with the proposed post-endocytic sorting proteins ERM-binding phosphoprotein 50 (EBP50), N-ethylmaleimide-sensitive factor (NSF), sorting nexin 1 (SNX1), and G protein-coupled receptor-associated sorting protein (GASP).
The Journal of biological chemistry 2004;279(52):54291-303.
2004: Birgitte Holst; Nicholas D Holliday; Anders Bach; Christian E Elling; Helen M Cox; Thue W Schwartz
Common structural basis for constitutive activity of the ghrelin receptor family.
The Journal of biological chemistry 2004;279(51):53806-17.
2004: Katrien Princen; Sigrid Hatse; Kurt Vermeire; Stefano Aquaro; Erik De Clercq; Lars-Ole Gerlach; Mette M Rosenkilde; Thue W Schwartz; Renato T Skerlj; Gary J Bridger; Dominique Schols
Inhibition of human immunodeficiency virus replication by a dual CCR5/CXCR4 antagonist.
Journal of virology 2004;78(23):12996-3006.
2004: Katherine A McLean; Peter J Holst; Lene Martini; Thue W Schwartz; Mette M Rosenkilde
Similar activation of signal transduction pathways by the herpesvirus-encoded chemokine receptors US28 and ORF74.
Virology 2004;325(2):241-51.
2004: Mette M Rosenkilde; Katherine A McLean; Peter J Holst; Thue W Schwartz
The CXC chemokine receptor encoded by herpesvirus saimiri, ECRF3, shows ligand-regulated signaling through Gi, Gq, and G12/13 proteins but constitutive signaling only through Gi and G12/13 proteins.
The Journal of biological chemistry 2004;279(31):32524-33.
2004: Mette M Rosenkilde; Thue W Schwartz
The chemokine system -- a major regulator of angiogenesis in health and disease.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2004;112(7-8):481-95.
2004: Birgitte Holst; Thue W Schwartz
Constitutive ghrelin receptor activity as a signaling set-point in appetite regulation.
Trends in pharmacological sciences 2004;25(3):113-7.
2004: Mette M Rosenkilde; Lars-Ole Gerlach; Janus S Jakobsen; Renato T Skerlj; Gary J Bridger; Thue W Schwartz
Molecular mechanism of AMD3100 antagonism in the CXCR4 receptor: transfer of binding site to the CXCR3 receptor.
The Journal of biological chemistry 2004;279(4):3033-41.
2004: Arne Heydorn; Birgitte P Søndergaard; Niels Hadrup; Birgitte Holst; Carol Renfrew Haft; Thue W Schwartz
Distinct in vitro interaction pattern of dopamine receptor subtypes with adaptor proteins involved in post-endocytotic receptor targeting.
FEBS letters 2004;556(1-3):276-80.
2003: Birgitte Holst; Adam Cygankiewicz; Tine Halkjaer Jensen; Michael Ankersen; Thue W Schwartz
High constitutive signaling of the ghrelin receptor--identification of a potent inverse agonist.
Molecular endocrinology (Baltimore, Md.) 2003;17(11):2201-10.
2003: Sigrid Hatse; Katrien Princen; Kurt Vermeire; Lars-Ole Gerlach; Mette M Rosenkilde; Thue W Schwartz; Gary J Bridger; Erik De Clercq; Dominique Schols
Mutations at the CXCR4 interaction sites for AMD3100 influence anti-CXCR4 antibody binding and HIV-1 entry.
FEBS letters 2003;546(2-3):300-6.
2003: Morten Lindow; Anneline Nansen; Christina Bartholdy; Anette Stryhn; Nils J V Hansen; Thomas P Boesen; Timothy Wells; Thue W Schwartz; Allan Randrup Thomsen
The virus-encoded chemokine vMIP-II inhibits virus-induced Tc1-driven inflammation.
Journal of virology 2003;77(13):7393-400.
2003: Birgitte Holst; Thue W Schwartz
Molecular mechanism of agonism and inverse agonism in the melanocortin receptors: Zn(2+) as a structural and functional probe.
Annals of the New York Academy of Sciences 2003;994():1-11.
2003: Maria Waldhoer; Paola Casarosa; Mette M Rosenkilde; Martine J Smit; Rob Leurs; Jennifer L Whistler; Thue W Schwartz
The carboxyl terminus of human cytomegalovirus-encoded 7 transmembrane receptor US28 camouflages agonism by mediating constitutive endocytosis.
The Journal of biological chemistry 2003;278(21):19473-82.
2003: Hans R Lüttichau; Ian Clark-Lewis; Peter Østrup Jensen; Claus Moser; Jan Gerstoft; Thue W Schwartz
A highly selective CCR2 chemokine agonist encoded by human herpesvirus 6.
The Journal of biological chemistry 2003;278(13):10928-33.
2003: Morten Lindow; Hans R Lüttichau; Thue W Schwartz
Viral leads for chemokine-modulatory drugs.
Trends in pharmacological sciences 2003;24(3):126-30.
2003: Lars-Ole Gerlach; Janus S Jakobsen; Kasper P Jensen; Mette R Rosenkilde; Renato T Skerlj; Ulf Ryde; Gary J Bridger; Thue W Schwartz
Metal ion enhanced binding of AMD3100 to Asp262 in the CXCR4 receptor.
Biochemistry 2003;42(3):710-7.
2003: Peter J Holst; Hans R Lüttichau; Thue W Schwartz; Mette M Rosenkilde
Virally encoded chemokines and chemokine receptors in the role of viral infections.
Contributions to microbiology 2003;10():232-52.
2002: Birgitte Holst; Christian E Elling; Thue W Schwartz
Metal ion-mediated agonism and agonist enhancement in melanocortin MC1 and MC4 receptors.
The Journal of biological chemistry 2002;277(49):47662-70.
2002: Thomas P Boesen; Bobby Soni; Thue W Schwartz; Torben Halkier
Single-chain vascular endothelial growth factor variant with antagonist activity.
The Journal of biological chemistry 2002;277(43):40335-41.
2002: Maria Waldhoer; Thomas N Kledal; Helen Farrell; Thue W Schwartz
Murine cytomegalovirus (CMV) M33 and human CMV US28 receptors exhibit similar constitutive signaling activities.
Journal of virology 2002;76(16):8161-8.
2002: Lene Martini; Hanne Hastrup; Birgitte Holst; Alberto Fraile-Ramos; Mark Marsh; Thue W Schwartz
NK1 receptor fused to beta-arrestin displays a single-component, high-affinity molecular phenotype.
Molecular pharmacology 2002;62(1):30-7.
2002: Claudio Costa-Neto; Ayumi A Miyakawa; João B Pesquero; Laerte Oliveira; Siv A Hjorth; Thue W Schwartz; Antonio C M Paiva
Interaction of a non-peptide agonist with angiotensin II AT1 receptor mutants.
Canadian journal of physiology and pharmacology 2002;80(5):413-7.
2002: Alberto Fraile-Ramos; Annegret Pelchen-Matthews; Thomas N Kledal; Helena Browne; Thue W Schwartz; Mark Marsh
Localization of HCMV UL33 and US27 in endocytic compartments and viral membranes.
Traffic (Copenhagen, Denmark) 2002;3(3):218-32.
2002: Anders Heding; Christian E Elling; Thue W Schwartz
Novel method for the study of receptor Ca2+ signalling exemplified by the NK1 receptor.
Journal of receptor and signal transduction research 2002;22(1-4):241-52.
2001: Peter J Holst; Mette M Rosenkilde; Denise Manfra; S C Chen; Maria T Wiekowski; Birgitte Holst; F Cifire; Martin Lipp; Thue W Schwartz; sergio lira
Tumorigenesis induced by the HHV8-encoded chemokine receptor requires ligand modulation of high constitutive activity.
The Journal of clinical investigation 2001;108(12):1789-96.
2001: LS Mizoue; Susan K Sullivan; David S King; Thomas N Kledal; Thue W Schwartz; Kevin B Bacon; Tracy M Handel
Molecular determinants of receptor binding and signaling by the CX3C chemokine fractalkine.
The Journal of biological chemistry 2001;276(36):33906-14.
2001: Hans R Lüttichau; Jan Gerstoft; Thue W Schwartz
MC148 encoded by human molluscum contagiosum poxvirus is an antagonist for human but not murine CCR8.
Journal of leukocyte biology 2001;70(2):277-82.
2001: Sigrid Hatse; Katrien Princen; Lars-Ole Gerlach; Gary J Bridger; Geoffrey Henson; Erik De Clercq; Thue W Schwartz; Dominique Schols
Mutation of Asp(171) and Asp(262) of the chemokine receptor CXCR4 impairs its coreceptor function for human immunodeficiency virus-1 entry and abrogates the antagonistic activity of AMD3100.
Molecular pharmacology 2001;60(1):164-73.
2001: Birgitte Holst; Hanne Hastrup; U Raffetseder; Lene Martini; Thue W Schwartz
Two active molecular phenotypes of the tachykinin NK1 receptor revealed by G-protein fusions and mutagenesis.
The Journal of biological chemistry 2001;276(23):19793-9.
2001: Alberto Fraile-Ramos; Thomas N Kledal; Annegret Pelchen-Matthews; K Bowers; Thue W Schwartz; Mark Marsh
The human cytomegalovirus US28 protein is located in endocytic vesicles and undergoes constitutive endocytosis and recycling.
Molecular biology of the cell 2001;12(6):1737-49.
2001: Lars-Ole Gerlach; Renato T Skerlj; Gary J Bridger; Thue W Schwartz
Molecular interactions of cyclam and bicyclam non-peptide antagonists with the CXCR4 chemokine receptor.
The Journal of biological chemistry 2001;276(17):14153-60.
2001: Hans R Lüttichau; I C Lewis; Jan Gerstoft; Thue W Schwartz
The herpesvirus 8-encoded chemokine vMIP-II, but not the poxvirus-encoded chemokine MC148, inhibits the CCR10 receptor.
European journal of immunology 2001;31(4):1217-20.
2001: Mette M Rosenkilde; Maria Waldhoer; Hans R Lüttichau; Thue W Schwartz
Virally encoded 7TM receptors.
Oncogene 2001;20(13):1582-93.
2001: Kristian K Jensen; L Martini; Thue W Schwartz
Enhanced fluorescence resonance energy transfer between spectral variants of green fluorescent protein through zinc-site engineering.
Biochemistry 2001;40(4):938-45.
2000: Mette M Rosenkilde; Thomas N Kledal; Peter J Holst; Thue W Schwartz
Selective elimination of high constitutive activity or chemokine binding in the human herpesvirus 8 encoded seven transmembrane oncogene ORF74.
The Journal of biological chemistry 2000;275(34):26309-15.
2000: Birgitte Holst; Christian E Elling; Thue W Schwartz
Partial agonism through a zinc-Ion switch constructed between transmembrane domains III and VII in the tachykinin NK(1) receptor.
Molecular pharmacology 2000;58(2):263-70.
2000: Claudio Costa-Neto; Ayumi A Miyakawa; Laerte Oliveira; Siv A Hjorth; Thue W Schwartz; Antonio C M Paiva
Mutational analysis of the interaction of the N- and C-terminal ends of angiotensin II with the rat AT(1A) receptor.
British journal of pharmacology 2000;130(6):1263-8.
2000: Mette M Rosenkilde; Thue W Schwartz
Potency of ligands correlates with affinity measured against agonist and inverse agonists but not against neutral ligand in constitutively active chemokine receptor.
Molecular pharmacology 2000;57(3):602-9.
2000: Christian E Elling; U Raffetseder; Susan M Nielsen; Thue W Schwartz
Disulfide bridge engineering in the tachykinin NK1 receptor.
Biochemistry 2000;39(4):667-75.
2000: Hans R Lüttichau; JT Stine; Thomas P Boesen; Anders H Johnsen; D Chantry; Jan Gerstoft; Thue W Schwartz
A highly selective CC chemokine receptor (CCR)8 antagonist encoded by the poxvirus molluscum contagiosum.
The Journal of experimental medicine 2000;191(1):171-80.
1999: Christian E Elling; K Thirstrup; Birgitte Holst; Thue W Schwartz
Conversion of agonist site to metal-ion chelator site in the beta(2)-adrenergic receptor.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(22):12322-7.
1999: PJ Klasse; MM Rosenkilde; Nathalie Signoret; Annegret Pelchen-Matthews; Thue W Schwartz; Mark Marsh
CD4-Chemokine receptor hybrids in human immunodeficiency virus type 1 infection.
Journal of virology 1999;73(9):7453-66.
1999: Mette M Rosenkilde; Thomas N Kledal; Hans Bräuner-Osborne; Thue W Schwartz
Agonists and inverse agonists for the herpesvirus 8-encoded constitutively active seven-transmembrane oncogene product, ORF-74.
The Journal of biological chemistry 1999;274(2):956-61.
1998: Thomas N Kledal; Mette M Rosenkilde; Thue W Schwartz
Selective recognition of the membrane-bound CX3C chemokine, fractalkine, by the human cytomegalovirus-encoded broad-spectrum receptor US28.
FEBS letters 1998;441(2):209-14.
1998: Mette M Rosenkilde; M Lucibello; Birgitte Holst; Thue W Schwartz
Natural agonist enhancing bis-His zinc-site in transmembrane segment V of the tachykinin NK3 receptor.
FEBS letters 1998;439(1-2):35-40.
1998: Thue W Schwartz; A P IJzerman
Principles of agonism: undressing efficacy.
Trends in pharmacological sciences 1998;19(11):433-6.
1998: Nathalie Signoret; MM Rosenkilde; PJ Klasse; Thue W Schwartz; Michael H Malim; James A Hoxie; Mark Marsh
Differential regulation of CXCR4 and CCR5 endocytosis.
Journal of cell science 1998;111 ( Pt 18)():2819-30.
1998: Susan M Nielsen; Christian E Elling; Thue W Schwartz
Split-receptors in the tachykinin neurokinin-1 system--mutational analysis of intracellular loop 3.
European journal of biochemistry / FEBS 1998;251(1-2):217-26.
1998: Birgitte Holst; Sannah Zoffmann; Christian E Elling; Siv A Hjorth; Thue W Schwartz
Steric hindrance mutagenesis versus alanine scan in mapping of ligand binding sites in the tachykinin NK1 receptor.
Molecular pharmacology 1998;53(1):166-75.
1998: S A Hjorth; C Orskov; Thue W Schwartz
Constitutive activity of glucagon receptor mutants.
Molecular endocrinology (Baltimore, Md.) 1998;12(1):78-86.
1997: Timothy Wells; Thue W Schwartz
Plagiarism of the host immune system: lessons about chemokine immunology from viruses.
Current opinion in biotechnology 1997;8(6):741-8.
1997: Nathalie Signoret; J Oldridge; Annegret Pelchen-Matthews; PJ Klasse; T Tran; Lawrence F Brass; MM Rosenkilde; Thue W Schwartz; W Holmes; Walter S Dallas; M A Luther; Timothy Wells; James A Hoxie; Mark Marsh
Phorbol esters and SDF-1 induce rapid endocytosis and down modulation of the chemokine receptor CXCR4.
The Journal of cell biology 1997;139(3):651-64.
1997: Thomas N Kledal; Mette M Rosenkilde; F Coulin; G Simmons; Anders H Johnsen; Sami Alouani; Christine A Power; Hans R Lüttichau; Jan Gerstoft; Paul R Clapham; Ian Clark-Lewis; Timothy Wells; Thue W Schwartz
A broad-spectrum chemokine antagonist encoded by Kaposi's sarcoma-associated herpesvirus.
Science (New York, N.Y.) 1997;277(5332):1656-9.
1997: G Turcatti; Sannah Zoffmann; John A Lowe; Susan E Drozda; G Chassaing; Thue W Schwartz; André Chollet
Characterization of non-peptide antagonist and peptide agonist binding sites of the NK1 receptor with fluorescent ligands.
The Journal of biological chemistry 1997;272(34):21167-75.
1997: Thue W Schwartz; S Perlman; M M Rosenkilde; Siv A Hjorth
How receptor mutagenesis may confirm or confuse receptor classification.
Annals of the New York Academy of Sciences 1997;812():71-84.
1997: Christian E Elling; K Thirstrup; Susan M Nielsen; Siv A Hjorth; Thue W Schwartz
Metal-ion sites as structural and functional probes of helix-helix interactions in 7TM receptors.
Annals of the New York Academy of Sciences 1997;814():142-51.
1997: Thue W Schwartz
[7TM receptors--from the olfactory system and new hormones against HIV infection].
Ugeskrift for laeger 1997;159(9):1239-45.
1997: S Perlman; Claudio Costa-Neto; Ayumi A Miyakawa; Hans T Schambye; Siv A Hjorth; Antonio C M Paiva; R A Rivero; W J Greenlee; Thue W Schwartz
Dual agonistic and antagonistic property of nonpeptide angiotensin AT1 ligands: susceptibility to receptor mutations.
Molecular pharmacology 1997;51(2):301-11.
1997: Christian E Elling; K Thirstrup; Susan M Nielsen; Siv A Hjorth; Thue W Schwartz
Engineering of metal-ion sites as distance constraints in structural and functional analysis of 7TM receptors.
Folding & design 1997;2(4):S76-80.
1996: H Hastrup; Thue W Schwartz
Septide and neurokinin A are high-affinity ligands on the NK-1 receptor: evidence from homologous versus heterologous binding analysis.
FEBS letters 1996;399(3):264-6.
1996: Siv A Hjorth; Kenneth Thirstrup; Thue W Schwartz
Radioligand-dependent discrepancy in agonist affinities enhanced by mutations in the kappa-opioid receptor.
Molecular pharmacology 1996;50(4):977-84.
1996: Siv A Hjorth; Thue W Schwartz
Glucagon and GLP-1 receptors: lessons from chimeric ligands and receptors.
Acta physiologica Scandinavica 1996;157(3):343-5.
1996: Thue W Schwartz; M M Rosenkilde
Is there a 'lock' for all agonist 'keys' in 7TM receptors?
Trends in pharmacological sciences 1996;17(6):213-6.
1996: Kenneth Thirstrup; Christian E Elling; Siv A Hjorth; Thue W Schwartz
Construction of a high affinity zinc switch in the kappa-opioid receptor.
The Journal of biological chemistry 1996;271(14):7875-8.
1996: M M O'Hare; Thue W Schwartz
Biosynthesis of neuropeptide Y in porcine tissues and generation of N-terminal fragments in neuroblastoma cell lines.
Peptides 1996;17(1):147-53.
1995: Siv A Hjorth; Kenneth Thirstrup; David K Grandy; Thue W Schwartz
Analysis of selective binding epitopes for the kappa-opioid receptor antagonist nor-binaltorphimine.
Molecular pharmacology 1995;47(6):1089-94.
1995: Christian E Elling; Susan M Nielsen; Thue W Schwartz
Conversion of antagonist-binding site to metal-ion site in the tachykinin NK-1 receptor.
Nature 1995;374(6517):74-7.
1995: H T Schambye; Siv A Hjorth; J Weinstock; Thue W Schwartz
Interaction between the nonpeptide angiotensin antagonist SKF-108,566 and histidine 256 (HisVI:16) of the angiotensin type 1 receptor.
Molecular pharmacology 1995;47(3):425-31.
1995: U Gether; John A Lowe; Thue W Schwartz
Tachykinin non-peptide antagonists: binding domain and molecular mode of action.
Biochemical Society transactions 1995;23(1):96-102.
1995: S Perlman; H T Schambye; R A Rivero; W J Greenlee; Siv A Hjorth; Thue W Schwartz
Non-peptide angiotensin agonist. Functional and molecular interaction with the AT1 receptor.
The Journal of biological chemistry 1995;270(4):1493-6.
1994: Siv A Hjorth; H T Schambye; W J Greenlee; Thue W Schwartz
Identification of peptide binding residues in the extracellular domains of the AT1 receptor.
The Journal of biological chemistry 1994;269(49):30953-9.
1994: Siv A Hjorth; K Adelhorst; B B Pedersen; O Kirk; Thue W Schwartz
Glucagon and glucagon-like peptide 1: selective receptor recognition via distinct peptide epitopes.
The Journal of biological chemistry 1994;269(48):30121-4.
1994: M M Rosenkilde; M Cahir; U Gether; Siv A Hjorth; Thue W Schwartz
Mutations along transmembrane segment II of the NK-1 receptor affect substance P competition with non-peptide antagonists but not substance P binding.
The Journal of biological chemistry 1994;269(45):28160-4.
1994: H T Schambye; B von Wijk; Siv A Hjorth; W Wienen; M Entzeroth; DJ Bergsma; Thue W Schwartz
Mutations in transmembrane segment VII of the AT1 receptor differentiate between closely related insurmountable and competitive angiotensin antagonists.
British journal of pharmacology 1994;113(2):331-3.
1994: U Gether; L Nilsson; John A Lowe; Thue W Schwartz
Specific residues at the top of transmembrane segment V and VI of the neurokinin-1 receptor involved in binding of the nonpeptide antagonist CP 96,345 [corrected].
The Journal of biological chemistry 1994;269(39):23959-64.
1994: H T Schambye; Siv A Hjorth; DJ Bergsma; G Sathe; Thue W Schwartz
Differentiation between binding sites for angiotensin II and nonpeptide antagonists on the angiotensin II type 1 receptors.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(15):7046-50.
1994: U Gether; Xavier Emonds-Alt; JC Brelière; T Fujii; D Hagiwara; Laurent Pradier; C Garret; T E Johansen; Thue W Schwartz
Evidence for a common molecular mode of action for chemically distinct nonpeptide antagonists at the neurokinin-1 (substance P) receptor.
Molecular pharmacology 1994;45(3):500-8.
1994: C J Jensen; N P Gerard; Thue W Schwartz; U Gether
The species selectivity of chemically distinct tachykinin nonpeptide antagonists is dependent on common divergent residues of the rat and human neurokinin-1 receptors.
Molecular pharmacology 1994;45(2):294-9.
1993: S Zoffmann; U Gether; Thue W Schwartz
Conserved HisVI-17 of the NK-1 receptor is involved in binding of non-peptide antagonists but not substance P.
FEBS letters 1993;336(3):506-10.
1993: H T Schambye; Siv A Hjorth; Thue W Schwartz
[Non-peptide antagonists to angiotensin II receptors. A review].
Ugeskrift for laeger 1993;155(44):3558-62.
1993: U Gether; T E Johansen; R M Snider; John A Lowe; Xavier Emonds-Alt; Y Yokota; S Nakanishi; Thue W Schwartz
Binding epitopes for peptide and non-peptide ligands on the NK1 (substance P) receptor.
Regulatory peptides 1993;46(1-2):49-58.
1993: U Gether; Y Yokota; Xavier Emonds-Alt; JC Brelière; John A Lowe; R M Snider; S Nakanishi; Thue W Schwartz
Two nonpeptide tachykinin antagonists act through epitopes on corresponding segments of the NK1 and NK2 receptors.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(13):6194-8.
1993: Birgitte S Wulff; T E Johansen; H Dalbøge; M M O'Hare; Thue W Schwartz
Processing of two homologous precursors, pro-neuropeptide Y and pro-pancreatic polypeptide, in transfected cell lines expressing different precursor convertases.
The Journal of biological chemistry 1993;268(18):13327-35.
1993: U Gether; T E Johansen; Thue W Schwartz
Chimeric NK1 (substance P)/NK3 (neurokinin B) receptors. Identification of domains determining the binding specificity of tachykinin agonists.
The Journal of biological chemistry 1993;268(11):7893-8.
1993: U Gether; T E Johansen; R M Snider; John A Lowe; S Nakanishi; Thue W Schwartz
Different binding epitopes on the NK1 receptor for substance P and non-peptide antagonist.
Nature 1993;362(6418):345-8.
1993: Birgitte S Wulff; B Catipovic; H Okamoto; U Gether; Thue W Schwartz; T E Johansen
Efficient amidation of C-peptide deleted NPY precursors by non-endocrine cells is affected by the presence of Lys-Arg at the C-terminus.
Molecular and cellular endocrinology 1993;91(1-2):135-41.
1992: U Gether; T Marray; Thue W Schwartz; T E Johansen
Stable expression of high affinity NK1 (substance P) and NK2 (neurokinin A) receptors but low affinity NK3 (neurokinin B) receptors in transfected CHO cells.
FEBS letters 1992;296(3):241-4.
1991: T E Johansen; Søren Schifter; C K Vogel; S Tolstoy; Thue W Schwartz
Processing of pro-CGRP in a rat medullary thyroid carcinoma cell line transfected with protease inhibitors.
Molecular and cellular endocrinology 1991;82(1):51-60.
1991: U Gether; L Aakerlund; Thue W Schwartz
Comparison of peptidyl-glycine alpha-amidation activity in medullary thyroid carcinoma cells, pheochromocytomas, and serum.
Molecular and cellular endocrinology 1991;79(1-3):53-63.
1991: T E Johansen; M M O'Hare; Birgitte S Wulff; Thue W Schwartz
CHO cells synthesize amidated neuropeptide Y from a C-peptide deleted form of the precursor.
Endocrinology 1991;129(1):553-5.
1990: J C Jørgensen; J Fuhlendorff; Thue W Schwartz
Structure-function studies on neuropeptide Y and pancreatic polypeptide--evidence for two PP-fold receptors in vas deferens.
European journal of pharmacology 1990;186(1):105-14.
1990: T E Johansen; M S Schøller; S Tolstoy; Thue W Schwartz
Biosynthesis of peptide precursors and protease inhibitors using new constitutive and inducible eukaryotic expression vectors.
FEBS letters 1990;267(2):289-94.
1990: J Fuhlendorff; Nils Langeland Johansen; S G Melberg; H Thøgersen; Thue W Schwartz
The antiparallel pancreatic polypeptide fold in the binding of neuropeptide Y to Y1 and Y2 receptors.
The Journal of biological chemistry 1990;265(20):11706-12.
1990: A J Vangsted; Thue W Schwartz
Production of gastrin-releasing peptide-(18-27) and a stable fragment of its precursor in small cell lung carcinoma cells.
The Journal of clinical endocrinology and metabolism 1990;70(6):1586-93.
1990: Birgitte S Wulff; M M O'Hare; E Boel; L E Theill; Thue W Schwartz
Partial processing of the neuropeptide Y precursor in transfected CHO cells.
FEBS letters 1990;261(1):101-5.
1990: L Aakerlund; U Gether; J Fuhlendorff; Thue W Schwartz; O Thastrup
Y1 receptors for neuropeptide Y are coupled to mobilization of intracellular calcium and inhibition of adenylate cyclase.
FEBS letters 1990;260(1):73-8.
1990: Thue W Schwartz; J Fuhlendorff; L L Kjems; M S Kristensen; M Vervelde; M O'Hare; John Leonard Krstenansky; B Bjørnholm
Signal epitopes in the three-dimensional structure of neuropeptide Y. Interaction with Y1, Y2, and pancreatic polypeptide receptors.
Annals of the New York Academy of Sciences 1990;611():35-47.
1990: J Fuhlendorff; U Gether; L Aakerlund; N Langeland-Johansen; H Thøgersen; S G Melberg; U B Olsen; O Thastrup; Thue W Schwartz
[Leu31, Pro34]neuropeptide Y: a specific Y1 receptor agonist.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(1):182-6.
1989: M M O'Hare; Thue W Schwartz
Expression and precursor processing of neuropeptide Y in human and murine neuroblastoma and pheochromocytoma cell lines.
Cancer research 1989;49(24 Pt 1):7015-9.
1989: M M O'Hare; Thue W Schwartz
Expression and precursor processing of neuropeptide Y in human pheochromocytoma and neuroblastoma tumors.
Cancer research 1989;49(24 Pt 1):7010-4.
1989: Søren P Sheikh; J J Holst; Cathrine Orskov; R Ekman; Thue W Schwartz
Release of PYY from pig intestinal mucosa; luminal and neural regulation.
Regulatory peptides 1989;26(3):253-66.
1989: Søren P Sheikh; M I Sheikh; Thue W Schwartz
Y2-type receptors for peptide YY on renal proximal tubular cells in the rabbit.
The American journal of physiology 1989;257(6 Pt 2):F978-84.
1989: Jens Juul Holst; M Hansen; E Bork; Thue W Schwartz
Elevated plasma concentrations of C-flanking gastrin-releasing peptide in small-cell lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1989;7(12):1831-8.
1989: J C Jørgensen; Søren P Sheikh; Axel Forman; M Nørgård; Thue W Schwartz; Bent Ottesen
Neuropeptide Y in the human female genital tract: localization and biological action.
The American journal of physiology 1989;257(2 Pt 1):E220-7.
1989: Michael Busch-Sørensen; Søren P Sheikh; M O'Hare; O Tortora; Thue W Schwartz; Steen Gammeltoft
Regional distribution of neuropeptide Y and its receptor in the porcine central nervous system.
Journal of neurochemistry 1989;52(5):1545-52.
1989: Søren P Sheikh; M M O'Hare; O Tortora; Thue W Schwartz
Binding of monoiodinated neuropeptide Y to hippocampal membranes and human neuroblastoma cell lines.
The Journal of biological chemistry 1989;264(12):6648-54.
1989: Søren P Sheikh; R Håkanson; Thue W Schwartz
Y1 and Y2 receptors for neuropeptide Y.
FEBS letters 1989;245(1-2):209-14.
1988: U Gether; H V Nielsen; Thue W Schwartz
Tyrosylation and purification of peptides for radioiodination.
Journal of chromatography 1988;447(2):341-9.
1988: Thue W Schwartz
Effect of amino acid analogs on the processing of the pancreatic polypeptide precursor in primary cell cultures.
The Journal of biological chemistry 1988;263(23):11504-10.
1988: Søren P Sheikh; Jens Juul Holst; T Skak-Nielsen; U Knigge; Jørgen Warberg; E Theodorsson-Norheim; T Hökfelt; J M Lundberg; Thue W Schwartz
Release of NPY in pig pancreas: dual parasympathetic and sympathetic regulation.
The American journal of physiology 1988;255(1 Pt 1):G46-54.
1988: M M O'Hare; S Tenmoku; L Aakerlund; Linda Hilsted; A Johnsen; Thue W Schwartz
Neuropeptide Y in guinea pig, rabbit, rat and man. Identical amino acid sequence and oxidation of methionine-17.
Regulatory peptides 1988;20(4):293-304.
1988: S Tenmoku; B Ottesen; M M O'Hare; S Sheikh; B Bardrum; B Hansen; B Walker; R F Murphy; Thue W Schwartz
Interaction of NPY and VIP in regulation of myometrial blood flow and mechanical activity.
Peptides 1988;9(2):269-75.
1987: Thue W Schwartz; Søren P Sheikh; M M O'Hare
Receptors on phaeochromocytoma cells for two members of the PP-fold family--NPY and PP.
FEBS letters 1987;225(1-2):209-14.
1987: Thue W Schwartz; H F Hansen; U Gether; L Aakerlund
Processing or inactivation of antimicrobial peptides.
Nature 1987;329(6139):494.
1987: M M O'Hare; O Tortora; U Gether; H V Nielsen; Thue W Schwartz
High-performance liquid chromatography of phenylthiocarbamyl derivatives of amino acids and side-chain derivatized amino acids.
Journal of chromatography 1987;389(2):379-88.
1986: H V Nielsen; U Gether; Thue W Schwartz
Cat pancreatic eicosapeptide and its biosynthetic intermediate. Conservation of a monobasic processing site.
The Biochemical journal 1986;240(1):69-74.