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Michael Schwarzschild

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Anne-Marie A Wills; Jiang-Fan Chen; Shirley Eberly; Cornelia Kamp; Anthony E Lang; Michael P McDermott; Susan Messing; David Oakes; Michael A Schwarzschild; Caroline M Tanner; Marsha Tennis; Daniel Togasaki
Caffeine consumption and risk of dyskinesia in CALM-PD.
Xiqun Chen; Sara Cipriani; Cody A Desjardins; Robert Logan; Thomas C Burdett; Yuehang Xu; Michael A Schwarzschild
Disrupted and transgenic urate oxidase alter urate and dopaminergic neurodegeneration.
Thomas C Burdett; Xiqun Chen; Cody A Desjardins; Robert Logan; Nikolaus R McFarland; Michael A Schwarzschild
Efficient determination of purine metabolites in brain tissue and serum by high-performance liquid chromatography with electrochemical and UV detection.

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2013: Anne-Marie A Wills; Jiang-Fan Chen; Shirley Eberly; Cornelia Kamp; Anthony E Lang; Michael P McDermott; Susan Messing; David Oakes; Michael A Schwarzschild; Caroline M Tanner; Marsha Tennis; Daniel Togasaki
Caffeine consumption and risk of dyskinesia in CALM-PD.
Movement disorders : official journal of the Movement Disorder Society 2013;28(3):380-3.
2013: Xiqun Chen; Sara Cipriani; Cody A Desjardins; Robert Logan; Thomas C Burdett; Yuehang Xu; Michael A Schwarzschild
Disrupted and transgenic urate oxidase alter urate and dopaminergic neurodegeneration.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(1):300-5.
2013: Thomas C Burdett; Xiqun Chen; Cody A Desjardins; Robert Logan; Nikolaus R McFarland; Michael A Schwarzschild
Efficient determination of purine metabolites in brain tissue and serum by high-performance liquid chromatography with electrochemical and UV detection.
Biomedical chromatography : BMC 2013;27(1):122-9.
2012: Sara Cipriani; Cody A Desjardins; Kui Xu; Yuehang Xu; Thomas C Burdett; Michael A Schwarzschild
Protection of dopaminergic cells by urate requires its accumulation in astrocytes.
Journal of neurochemistry 2012;123(1):172-81.
2012: Natalia Palacios; Michael A Schwarzschild; Roma Shah; Xiang Gao; Susan Gapstur; Marjorie L McCullough; Alberto Ascherio
Caffeine and risk of Parkinson's disease in a large cohort of men and women.
Movement disorders : official journal of the Movement Disorder Society 2012;27(10):1276-82.
2012: Michael A Schwarzschild
Caffeine in Parkinson disease: better for cruise control than snooze patrol?
Neurology 2012;79(7):616-8.
2012: Xiqun Chen; Guanhui Wu; Michael A Schwarzschild
Urate in Parkinson's disease: more than a biomarker?
Current neurology and neuroscience reports 2012;12(4):367-75.
2012: Marco Matos; Alexandre Dos Santos-Rodrigues; Michael A Schwarzschild; Elisabete Augusto; Jiang-Fan Chen; Rodrigo A Cunha; Paula M.G. Agostinho
Adenosine A2A receptors modulate glutamate uptake in cultured astrocytes and gliosomes.
Glia 2012;60(5):702-16.
2012: Xiang Gao; Michael A Schwarzschild; Kelly C Simon; Alberto Ascherio
Prospective study of statin use and risk of Parkinson disease.
Archives of neurology 2012;69(3):380-4.
2012: Anil Kachroo; Michael A Schwarzschild
Adenosine A2A receptor gene disruption protects in an α-synuclein model of Parkinson's disease.
Annals of neurology 2012;71(2):278-82.
2012: Sara Cipriani; Cody A Desjardins; Kui Xu; Yuehang Xu; Thomas C Burdett; Michael A Schwarzschild
Urate and its transgenic depletion modulate neuronal vulnerability in a cellular model of Parkinson's disease.
PloS one 2012;7(5):e37331.
2011: Hongliu Ding; Alice W Flaherty; John H Growdon; Michael T Hayes; Albert Y Hung; Bradley T Hyman; Adrian J Ivinson; Caroline G Kan; Nancy E Maher; Bernard M Ravina; Sarah S Roderick; Andrea Santarlasci; Alison K Sarokhan; Michael G Schlossmacher; Michael A Schwarzschild; Dennis J Selkoe; U Shivraj Sohur; Lewis R Sudarsky; Kyleen E Swords; Vivek K Unni; Anne-Marie Wills; Paymon Ashourian; Rachit Bakshi; Sunny Chang; Clemens R Scherzer
Association of SNCA with Parkinson: replication in the Harvard NeuroDiscovery Center Biomarker Study.
Movement disorders : official journal of the Movement Disorder Society 2011;26(12):2283-6.
2011: Natalia Palacios; Alpa V Patel; Michael A Schwarzschild; Xiang Gao; Eric J Jacobs; Tinisha Mayo; Marjorie L McCullough; Alberto Ascherio
Obesity, diabetes, and risk of Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2011;26(12):2253-9.
2011: Xiang Gao; Michael A Schwarzschild; Honglei Chen; Alberto Ascherio
A prospective study of bowel movement frequency and risk of Parkinson's disease.
American journal of epidemiology 2011;174(5):546-51.
2011: Michael A Schwarzschild; John Seibyl; Ira Shoulson; Alberto Ascherio; Shirley Eberly; Danna Jennings; Kenneth Marek; David Oakes
Serum urate and probability of dopaminergic deficit in early "Parkinson's disease".
Movement disorders : official journal of the Movement Disorder Society 2011;26(10):1864-8.
2011: Melita T Barkhoudarian; Michael A Schwarzschild
Preclinical jockeying on the translational track of adenosine A2A receptors.
Experimental neurology 2011;228(2):160-4.
2011: Xiang Gao; Honglei Chen; Michael A Schwarzschild; Alberto Ascherio
Use of ibuprofen and risk of Parkinson disease.
Neurology 2011;76(10):863-9.
2011: Danqing Xiao; Jared J Cassin; Brian Healy; Thomas C Burdett; Jiang-Fan Chen; Bertil B Fredholm; Michael A Schwarzschild
Deletion of adenosine A₁ or A(₂A) receptors reduces L-3,4-dihydroxyphenylalanine-induced dyskinesia in a model of Parkinson's disease.
Brain research 2011;1367():310-8.
2010: Yolanda D Black; Danqing Xiao; Daniela Pellegrino; Anil Kachroo; Anna-Liisa Brownell; Michael A Schwarzschild
Protective effect of metabotropic glutamate mGluR5 receptor elimination in a 6-hydroxydopamine model of Parkinson's disease.
Neuroscience letters 2010;486(3):161-5.
2010: Michael A Schwarzschild
The delayed-start study in Parkinson disease: can't satisfy everyone: Rasagiline, Parkinson neuroprotection, and delayed-start trials: still no satisfaction?
Neurology 2010;75(21):1943-4; author reply 1944-5.
2010: Xiang Gao; Michael A Schwarzschild; Eilis J O'Reilly; Hao Wang; Alberto Ascherio
Restless legs syndrome and Parkinson's disease in men.
Movement disorders : official journal of the Movement Disorder Society 2010;25(15):2654-7.
2010: Sara Cipriani; Xiqun Chen; Michael A Schwarzschild
Urate: a novel biomarker of Parkinson's disease risk, diagnosis and prognosis.
Biomarkers in medicine 2010;4(5):701-12.
2010: Eilis J O'Reilly; Xiang Gao; Marc G Weisskopf; Honglei Chen; Michael A Schwarzschild; Donna Spiegelman; Alberto Ascherio
Plasma urate and Parkinson's disease in women.
American journal of epidemiology 2010;172(6):666-70.
2010: Kelly Claire Simon; Xiang Gao; Honglei Chen; Michael A Schwarzschild; Alberto Ascherio
Calcium channel blocker use and risk of Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2010;25(12):1818-22.
2010: Hannah Gardener; Xiang Gao; Honglei Chen; Michael A Schwarzschild; Donna Spiegelman; Alberto Ascherio
Prenatal and early life factors and risk of Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2010;25(11):1560-7.
2010: N Palacios; Marc G Weisskopf; K Simon; Xiang Gao; Michael A Schwarzschild; Alberto Ascherio
Polymorphisms of caffeine metabolism and estrogen receptor genes and risk of Parkinson's disease in men and women.
Parkinsonism & related disorders 2010;16(6):370-5.
2010: Anil Kachroo; Michael C Irizarry; Michael A Schwarzschild
Caffeine protects against combined paraquat and maneb-induced dopaminergic neuron degeneration.
Experimental neurology 2010;223(2):657-61.
2010: K Xu; Yue-Hang Xu; Jiang-Fan Chen; Michael A Schwarzschild
Neuroprotection by caffeine: time course and role of its metabolites in the MPTP model of Parkinson's disease.
Neuroscience 2010;167(2):475-81.
2010: Michael A Schwarzschild
Rasagiline in Parkinson's disease.
The New England journal of medicine 2010;362(7):658; author reply 658-9.
2010: Micaela Morelli; Anna R Carta; Anil Kachroo; Michael A Schwarzschild
Pathophysiological roles for purines: adenosine, caffeine and urate.
Progress in brain research 2010;183():183-208.
2010: Xiang Gao; Michael A Schwarzschild; Eilis J O'Reilly; H Wang; Alberto Ascherio
Restless legs syndrome and erectile dysfunction.
Sleep 2010;33(1):75-9.
2009: Alberto Ascherio; Peter LeWitt; Kui Xu; Shirley Eberly; Arthur Watts; Wayne R Matson; Connie Marras; Karl Kieburtz; Alice Rudolph; Mikhail B Bogdanov; Steven R Schwid; Marsha Tennis; Caroline M Tanner; M Flint Beal; Anthony E Lang; David Oakes; Stanley Fahn; Ira Shoulson; Michael A Schwarzschild
Urate as a predictor of the rate of clinical decline in Parkinson disease.
Archives of neurology 2009;66(12):1460-8.
2009: Anna R Carta; Anil Kachroo; Nicoletta Schintu; Kui Xu; Michael A Schwarzschild; Jadwiga Wardas; Micaela Morelli
Inactivation of neuronal forebrain A receptors protects dopaminergic neurons in a mouse model of Parkinson's disease.
Journal of neurochemistry 2009;111(6):1478-89.
2009: X Gao; K C Simon; Jiali Han; Michael A Schwarzschild; Alberto Ascherio
Family history of melanoma and Parkinson disease risk.
Neurology 2009;73(16):1286-91.
2009: Kelly Claire Simon; Honglei Chen; Xiang Gao; Michael A Schwarzschild; Alberto Ascherio
Reproductive factors, exogenous estrogen use, and risk of Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2009;24(9):1359-65.
2009: Nikolaus R McFarland; Zhanyun Fan; Kui Xu; Michael A Schwarzschild; Mel B Feany; Bradley T Hyman; Pamela J McLean
Alpha-synuclein S129 phosphorylation mutants do not alter nigrostriatal toxicity in a rat model of Parkinson disease.
Journal of neuropathology and experimental neurology 2009;68(5):515-24.
2009: Xiang Gao; Michael A Schwarzschild; Hao Wang; Alberto Ascherio
Obesity and restless legs syndrome in men and women.
Neurology 2009;72(14):1255-61.
2009: Eilis J O'Reilly; Honglei Chen; Hannah Gardener; Xiang Gao; Michael A Schwarzschild; Alberto Ascherio
Smoking and Parkinson's disease: using parental smoking as a proxy to explore causality.
American journal of epidemiology 2009;169(6):678-82.
2009: Jiang-Ning Yang; Olga Björklund; Karin Lindström-Törnqvist; Eva Lindgren; Therese M Eriksson; Johan Kahlström; Jiang-Fan Chen; Michael A Schwarzschild; Irene Tobler; Bertil B. Fredholm
Mice heterozygous for both A1 and A(2A) adenosine receptor genes show similarities to mice given long-term caffeine.
Journal of applied physiology (Bethesda, Md. : 1985) 2009;106(2):631-9.
2009: César Quiroz; Rafael Luján; Motokazu Uchigashima; Ana Patrícia Simoes; Talia N Lerner; Janusz Borycz; Anil Kachroo; Paula M Canas; Marco Orru; Michael A Schwarzschild; Diane L Rosin; Anatol C Kreitzer; Rodrigo A Cunha; Masahiko Watanabe; Sergi Ferré
Key modulatory role of presynaptic adenosine A2A receptors in cortical neurotransmission to the striatal direct pathway.
TheScientificWorldJournal 2009;9():1321-44.
2009: Xiang Gao; Kelly C Simon; Jiali Han; Michael A Schwarzschild; Alberto Ascherio
Genetic determinants of hair color and Parkinson's disease risk.
Annals of neurology 2009;65(1):76-82.
2009: Jeff Bronstein; Paul Carvey; Honglei Chen; Deborah Cory-Slechta; Donato DiMonte; John Duda; Paul English; Samuel Goldman; Stephen Grate; Johnni Hansen; Jane Hoppin; Sarah Jewell; Freya Kamel; Walter J Koroshetz; J William Langston; Giancarlo Logroscino; Lorene Nelson; Bernard Ravina; Walter Rocca; George Ross; Ted Schettler; Michael A Schwarzschild; Bill Scott; Richard Seegal; Andrew Singleton; Nelson STEENLAND; Caroline M Tanner; Stephen K Van Den Eeden; Marc Weisskopf
Meeting report: consensus statement-Parkinson's disease and the environment: collaborative on health and the environment and Parkinson's Action Network (CHE PAN) conference 26-28 June 2007.
Environmental health perspectives 2009;117(1):117-21.
2009: Jacobus P Petzer; Neal Castagnoli; Michael A Schwarzschild; Jiang-Fan Chen; Cornelis J Van Der Schyf
Dual-target-directed drugs that block monoamine oxidase B and adenosine A(2A) receptors for Parkinson's disease.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2009;6(1):141-51.
2009: Michael C Irizarry; Rema Raman; Michael A Schwarzschild; Lida M Becerra; Ronald G Thomas; Ronald C Peterson; Alberto Ascherio; Paul S Aisen
Plasma urate and progression of mild cognitive impairment.
Neuro-degenerative diseases 2009;6(1-2):23-8.
2008: Eugene I Tikh; Richard A Fenton; Jiang-Fan Chen; Michael A Schwarzschild; James G Dobson
Adenosine A1 and A2A receptor regulation of protein phosphatase 2A in the murine heart.
Journal of cellular physiology 2008;216(1):83-90.
2008: Michael A Schwarzschild; Steven R Schwid; Kenneth Marek; Arthur Watts; Anthony E Lang; David Oakes; Ira Shoulson; Alberto Ascherio; Christopher Hyson; Emily Gorbold; Alice Rudolph; Karl Kieburtz; Stanley Fahn; Lisa Gauger; Christopher G Goetz; John P Seibyl; Misser Forrest; John Ondrasik
Serum urate as a predictor of clinical and radiographic progression in Parkinson disease.
Archives of neurology 2008;65(6):716-23.
2008: Xiang Gao; Honglei Chen; Hyon K Choi; Gary Curhan; Michael A Schwarzschild; Alberto Ascherio
Diet, urate, and Parkinson's disease risk in men.
American journal of epidemiology 2008;167(7):831-8.
2008: Xiang Gao; Honglei Chen; Michael A Schwarzschild; Giancarlo Logroscino; Alberto Ascherio
Perceived imbalance and risk of Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2008;23(4):613-6.
2008: Hao Wang; Honglei Chen; Xiang Gao; Monica McGrath; Dwayne Deer; Immaculata DeVivo; Michael A Schwarzschild; Alberto Ascherio
Telomere length and risk of Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2008;23(2):302-5.
2008: Maria Teresa Tebano; Alberto Martire; Rosa Luisa Potenza; C Grò; Rita Pepponi; M Armida; Maria Rosaria Domenici; Michael A Schwarzschild; J F Chen; Patrizia Popoli
Adenosine A(2A) receptors are required for normal BDNF levels and BDNF-induced potentiation of synaptic transmission in the mouse hippocampus.
Journal of neurochemistry 2008;104(1):279-86.
2008: Evan L Thacker; Honglei Chen; Alpa V Patel; Marjorie L McCullough; Eugenia E Calle; Michael J Thun; Michael A Schwarzschild; Alberto Ascherio
Recreational physical activity and risk of Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2008;23(1):69-74.
2008: Honglei Chen; Eilis J O'Reilly; Michael A Schwarzschild; Alberto Ascherio
Peripheral inflammatory biomarkers and risk of Parkinson's disease.
American journal of epidemiology 2008;167(1):90-5.
2007: Xiang Gao; Honglei Chen; Michael A Schwarzschild; Dale B Glasser; Giancarlo Logroscino; Eric B Rimm; Alberto Ascherio
Erectile function and risk of Parkinson's disease.
American journal of epidemiology 2007;166(12):1446-50.
2007: Michael A Schwarzschild
Adenosine A2A antagonists as neurotherapeutics: crossing the bridge.
Progress in neurobiology 2007;83(5):261-2.
2007: Micaela Morelli; Therese Di Paolo; Jadwiga Wardas; Frederic Calon; Danqing Xiao; Michael A Schwarzschild
Role of adenosine A2A receptors in parkinsonian motor impairment and l-DOPA-induced motor complications.
Progress in neurobiology 2007;83(5):293-309.
2007: Xiang Gao; Honglei Chen; Teresa T Fung; Giancarlo Logroscino; Michael A Schwarzschild; Frank B Hu; Alberto Ascherio
Prospective study of dietary pattern and risk of Parkinson disease.
The American journal of clinical nutrition 2007;86(5):1486-94.
2007: Kelly Claire Simon; Honglei Chen; Michael A Schwarzschild; Alberto Ascherio
Hypertension, hypercholesterolemia, diabetes, and risk of Parkinson disease.
Neurology 2007;69(17):1688-95.
2007: Marc G Weisskopf; Eilis J O'Reilly; Honglei Chen; Michael A Schwarzschild; Alberto Ascherio
Plasma urate and risk of Parkinson's disease.
American journal of epidemiology 2007;166(5):561-7.
2007: Albert Y Hung; Michael A Schwarzschild
Clinical trials for neuroprotection in Parkinson's disease: overcoming angst and futility?
Current opinion in neurology 2007;20(4):477-83.
2007: Honglei Chen; Eilis J O'Reilly; Marjorie L McCullough; Carmen Rodriguez; Michael A Schwarzschild; Eugenia E Calle; Michael J Thun; Alberto Ascherio
Consumption of dairy products and risk of Parkinson's disease.
American journal of epidemiology 2007;165(9):998-1006.
2007: E L Thacker; Eilis J O'Reilly; Marc G Weisskopf; Honglei Chen; Michael A Schwarzschild; Marjorie L McCullough; Eugenia E Calle; Michael J Thun; Alberto Ascherio
Temporal relationship between cigarette smoking and risk of Parkinson disease.
Neurology 2007;68(10):764-8.
2007: Clemens R Scherzer; Aron C Eklund; Lee J Morse; Zhixiang Liao; Joseph J Locascio; Daniel Fefer; Michael A Schwarzschild; Michael G Schlossmacher; Michael A Hauser; Jeffery Vance; Lewis R Sudarsky; David G Standaert; John H Growdon; Roderick V Jensen; Steven R Gullans
Molecular markers of early Parkinson's disease based on gene expression in blood.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(3):955-60.
2006: Danqing Xiao; Elena Bastia; Yue-Hang Xu; Caroline L Benn; Jang-Ho Cha; Tracy S Peterson; Jiang-Fan Chen; Michael A Schwarzschild
Forebrain adenosine A2A receptors contribute to L-3,4-dihydroxyphenylalanine-induced dyskinesia in hemiparkinsonian mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(52):13548-55.
2006: Michael A Schwarzschild; Luigi F Agnati; Kjell Fuxe; Jiang-Fan Chen; Micaela Morelli
Targeting adenosine A2A receptors in Parkinson's disease.
Trends in neurosciences 2006;29(11):647-54.
2006: Anthony H V Schapira; Erwan Bezard; Jonathan M Brotchie; Frederic Calon; Graham Collingridge; Boris Ferger; Bastian Hengerer; Etienne Hirsch; Peter Jenner; Nicolas Le Novère; Jose A Obeso; Michael A Schwarzschild; Umberto Spampinato; Giora Davidai
Novel pharmacological targets for the treatment of Parkinson's disease.
Nature reviews. Drug discovery 2006;5(10):845-54.
2006: Edwin S L Chan; Patricia Fernandez; A A Merchant; M Carmen Montesinos; S Trzaska; Avani Desai; C F Tung; D N Khoa; Michael H Pillinger; Allison B Reiss; Marjana Tomic; Jiang-Fan Chen; Michael A Schwarzschild; Bruce N Cronstein
Adenosine A2A receptors in diffuse dermal fibrosis: pathogenic role in human dermal fibroblasts and in a murine model of scleroderma.
Arthritis and rheumatism 2006;54(8):2632-42.
2006: Alberto Ascherio; Honglei Chen; Marc G Weisskopf; Eilis J O'Reilly; Marjorie L McCullough; Eugenia E Calle; Michael A Schwarzschild; Michael J Thun
Pesticide exposure and risk for Parkinson's disease.
Annals of neurology 2006;60(2):197-203.
2006: Edwin S L Chan; M Carmen Montesinos; Patricia Fernandez; Avani Desai; David L Delano; Herman Yee; Allison B Reiss; Michael H Pillinger; Jiang-Fan Chen; Michael A Schwarzschild; Scott L Friedman; Bruce N Cronstein
Adenosine A(2A) receptors play a role in the pathogenesis of hepatic cirrhosis.
British journal of pharmacology 2006;148(8):1144-55.
2006: Honglei Chen; Shumin M Zhang; Michael A Schwarzschild; Miguel A Hernán; Alberto Ascherio
Survival of Parkinson's disease patients in a large prospective cohort of male health professionals.
Movement disorders : official journal of the Movement Disorder Society 2006;21(7):1002-7.
2006: Honglei Chen; Eva S Schernhammer; Michael A Schwarzschild; Alberto Ascherio
A prospective study of night shift work, sleep duration, and risk of Parkinson's disease.
American journal of epidemiology 2006;163(8):726-30.
2006: Liqun Yu; Michael A Schwarzschild; Jiang-Fan Chen
Cross-sensitization between caffeine- and L-dopa-induced behaviors in hemiparkinsonian mice.
Neuroscience letters 2006;393(1):31-5.
2006: Kui Xu; Yuehang Xu; Deborah Brown-Jermyn; Jiang-Fan Chen; Alberto Ascherio; Dean E Dluzen; Michael A Schwarzschild
Estrogen prevents neuroprotection by caffeine in the mouse 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(2):535-41.
2005: Honglei Chen; Eric Jacobs; Michael A Schwarzschild; Marjorie L McCullough; Eugenia E Calle; Michael J Thun; Alberto Ascherio
Nonsteroidal antiinflammatory drug use and the risk for Parkinson's disease.
Annals of neurology 2005;58(6):963-7.
2005: Anil Kachroo; Lianna R Orlando; David K Grandy; Jiang-Fan Chen; Anne B Young; Michael A Schwarzschild
Interactions between metabotropic glutamate 5 and adenosine A2A receptors in normal and parkinsonian mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(45):10414-9.
2005: Maria Teresa Tebano; Alberto Martire; Nelson Rebola; Rita Pepponi; Maria Rosaria Domenici; Maria Cristina Grò; Michael A Schwarzschild; J F Chen; Rodrigo A Cunha; Patrizia Popoli
Adenosine A2A receptors and metabotropic glutamate 5 receptors are co-localized and functionally interact in the hippocampus: a possible key mechanism in the modulation of N-methyl-D-aspartate effects.
Journal of neurochemistry 2005;95(4):1188-200.
2005: Josep Saura; Ester Angulo; Aroa Ejarque-Ortiz; Vicent Casadó; Josep M Tusell; Rosario Moratalla; Jiang-Fan Chen; Michael A Schwarzschild; Carmen Lluis; Rafael Franco; Joan Serratosa
Adenosine A2A receptor stimulation potentiates nitric oxide release by activated microglia.
Journal of neurochemistry 2005;95(4):919-29.
2005: Liqun Yu; Peter M Haverty; Juliana Mariani; Yumei Wang; Hai-Ying Shen; Michael A Schwarzschild; Zhiping Weng; Jiang-Fan Chen
Genetic and pharmacological inactivation of adenosine A2A receptor reveals an Egr-2-mediated transcriptional regulatory network in the mouse striatum.
Physiological genomics 2005;23(1):89-102.
2005: Raphaël Frédérick; Fred Ooms; Neal Castagnoli; Jacobus P Petzer; Jiang-Fan Feng; Michael A Schwarzschild; Cornelis J Van Der Schyf; Johan Wouters
(E)-8-(3-Chlorostyryl)-1,3,7-trimethylxanthine, a caffeine derivative acting both as antagonist of adenosine A2A receptors and as inhibitor of MAO-B.
Acta crystallographica. Section C, Crystal structure communications 2005;61(Pt 9):o531-2.
2005: Zhi-Li Huang; Wei-Min Qu; Naomi Eguchi; Jiang-Fan Chen; Michael A Schwarzschild; Bertil B. Fredholm; Yoshihiro Urade; Osamu Hayaishi
Adenosine A2A, but not A1, receptors mediate the arousal effect of caffeine.
Nature neuroscience 2005;8(7):858-9.
2005: Elena Bastia; Yue-Hang Xu; Angela C Scibelli; Yuan-Ji Day; Joel Linden; Jiang-Fan Chen; Michael A Schwarzschild
A crucial role for forebrain adenosine A(2A) receptors in amphetamine sensitization.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2005;30(5):891-900.
2005: Kui Xu; Elena Bastia; Michael A Schwarzschild
Therapeutic potential of adenosine A(2A) receptor antagonists in Parkinson's disease.
Pharmacology & therapeutics 2005;105(3):267-310.
2005: Honglei Chen; Shumin M Zhang; Michael A Schwarzschild; Miguel A Hernán; Alberto Ascherio
Physical activity and the risk of Parkinson disease.
Neurology 2005;64(4):664-9.
2005: Robert A Hauser; Michael A Schwarzschild
Adenosine A2A receptor antagonists for Parkinson's disease: rationale, therapeutic potential and clinical experience.
Drugs & aging 2005;22(6):471-82.
2004: Honglei Chen; Shumin M Zhang; Michael A Schwarzschild; Miguel A Hernán; Giancarlo Logroscino; Walter C Willett; Alberto Ascherio
Folate intake and risk of Parkinson's disease.
American journal of epidemiology 2004;160(4):368-75.
2004: Jonathan W Francis; Elena Bastia; Christopher Matthews; Deborah A Parks; Michael A Schwarzschild; Robert H Brown; Paul S Fishman
Tetanus toxin fragment C as a vector to enhance delivery of proteins to the CNS.
Brain research 2004;1011(1):7-13.
2004: Honglei Chen; Shumin M Zhang; Michael A Schwarzschild; Miguel A Hernán; Walter C Willett; Alberto Ascherio
Obesity and the risk of Parkinson's disease.
American journal of epidemiology 2004;159(6):547-55.
2004: Liqun Yu; Martin C Frith; Yutaka Suzuki; Robert A Peterfreund; Tom Gearan; Sumio Sugano; Michael A Schwarzschild; Zhiping Weng; J Stephen Fink; Jiang-Fan Chen
Characterization of genomic organization of the adenosine A2A receptor gene by molecular and bioinformatics analyses.
Brain research 2004;1000(1-2):156-73.
2004: J Stephen Fink; Anti Kalda; Hoon Ryu; Edward C Stack; Michael A Schwarzschild; Jiang-Fan Chen; Robert J Ferrante
Genetic and pharmacological inactivation of the adenosine A2A receptor attenuates 3-nitropropionic acid-induced striatal damage.
Journal of neurochemistry 2004;88(3):538-44.
2004: Anthone W Dunah; Ana C Sirianni; Allen Fienberg; Elena Bastia; Michael A Schwarzschild; David G Standaert
Dopamine D1-dependent trafficking of striatal N-methyl-D-aspartate glutamate receptors requires Fyn protein tyrosine kinase but not DARPP-32.
Molecular pharmacology 2004;65(1):121-9.
2003: Yoshihiro Urade; Naomi Eguchi; Wei-Min Qu; Mie Sakata; Zhi-Li Huang; Jiang-Fan Chen; Michael A Schwarzschild; J Stephen Fink; Osamu Hayaishi
Sleep regulation in adenosine A2A receptor-deficient mice.
Neurology 2003;61(11 Suppl 6):S94-6.
2003: Jiang-Fan Chen; Silva Fredduzzi; Elena Bastia; Liqun Yu; Rosario Moratalla; Ennio Ongini; Michael A Schwarzschild
Adenosine A2A receptors in neuroadaptation to repeated dopaminergic stimulation: implications for the treatment of dyskinesias in Parkinson's disease.
Neurology 2003;61(11 Suppl 6):S74-81.
2003: Neal Castagnoli; Jacobus P Petzer; Salome Steyn; Kay Castagnoli; Jiang-Fan Chen; Michael A Schwarzschild; Cornelis J Van Der Schyf
Monoamine oxidase B inhibition and neuroprotection: studies on selective adenosine A2A receptor antagonists.
Neurology 2003;61(11 Suppl 6):S62-8.
2003: Michael A Schwarzschild; Kui Xu; Emin Oztas; Jacobus P Petzer; Kay Castagnoli; Neal Castagnoli; Jiang-Fan Chen
Neuroprotection by caffeine and more specific A2A receptor antagonists in animal models of Parkinson's disease.
Neurology 2003;61(11 Suppl 6):S55-61.
2003: Francesco Bibbiani; Justin D Oh; Jacobus P Petzer; Neal Castagnoli; Jiang-Fan Chen; Michael A Schwarzschild; Thomas N Chase
A2A antagonist prevents dopamine agonist-induced motor complications in animal models of Parkinson's disease.
Experimental neurology 2003;184(1):285-94.
2003: Yuan-Ji Day; Liping Huang; Marcia McDuffie; Diane L Rosin; Hong Ye; Jiang-Fan Chen; Michael A Schwarzschild; J Stephen Fink; Joel Linden; Mark D Okusa
Renal protection from ischemia mediated by A2A adenosine receptors on bone marrow-derived cells.
The Journal of clinical investigation 2003;112(6):883-91.
2003: Honglei Chen; Shumin M Zhang; Miguel A Hernán; Michael A Schwarzschild; Walter C Willett; GRaham Colditz; Frank E Speizer; Alberto Ascherio
Nonsteroidal anti-inflammatory drugs and the risk of Parkinson disease.
Archives of neurology 2003;60(8):1059-64.
2003: Miguel A Hernán; Honglei Chen; Michael A Schwarzschild; Alberto Ascherio
Alcohol consumption and the incidence of Parkinson's disease.
Annals of neurology 2003;54(2):170-5.
2003: Marc G Weisskopf; Honglei Chen; Michael A Schwarzschild; Ichiro Kawachi; Alberto Ascherio
Prospective study of phobic anxiety and risk of Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2003;18(6):646-51.
2003: Jiang-Fan Chen; Rosario Moratalla; Liqun Yu; Ana B Martín; Kui Xu; Elena Bastia; Elizabeth Hackett; Israel Alberti; Michael A Schwarzschild
Inactivation of adenosine A2A receptors selectively attenuates amphetamine-induced behavioral sensitization.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2003;28(6):1086-95.
2003: Jacobus P Petzer; Salome Steyn; Kay Castagnoli; Jiang-Fan Chen; Michael A Schwarzschild; Cornelis J Van Der Schyf; Neal Castagnoli
Inhibition of monoamine oxidase B by selective adenosine A2A receptor antagonists.
Bioorganic & medicinal chemistry 2003;11(7):1299-310.
2003: Alberto Ascherio; Honglei Chen; Michael A Schwarzschild; Shumin M Zhang; GRaham Colditz; FE Speizer
Caffeine, postmenopausal estrogen, and risk of Parkinson's disease.
Neurology 2003;60(5):790-5.
2003: Teresa Gomez-Isla; Michael C Irizarry; Ami Mariash; Bonnie Cheung; Oscar Soto; Stefanie Schrump; Jesse Sondel; Linda Kotilinek; John Day; Michael A Schwarzschild; Jang-Ho Cha; Kathy Newell; David W Miller; Kenji Uéda; Anne B Young; Bradley T Hyman; Karen K. Hsiao Ashe
Motor dysfunction and gliosis with preserved dopaminergic markers in human alpha-synuclein A30P transgenic mice.
Neurobiology of aging 2003;24(2):245-58.
2003: Elena Bastia; Michael A Schwarzschild
DARPP chocolate: a caffeinated morsel of striatal signaling.
Science's STKE : signal transduction knowledge environment 2003;2003(165):PE2.
2002: Jiang-Fan Chen; Salome Steyn; Roland Staal; Jacobus P Petzer; Kui Xu; Cornelis J Van Der Schyf; Kay Castagnoli; Patricia K Sonsalla; Neal Castagnoli; Michael A Schwarzschild
8-(3-Chlorostyryl)caffeine may attenuate MPTP neurotoxicity through dual actions of monoamine oxidase inhibition and A2A receptor antagonism.
The Journal of biological chemistry 2002;277(39):36040-4.
2002: S Joseph Leibovich; Jiang-Fan Chen; Grace Pinhal-Enfield; Paula C Belem; Genie Elson; Anthony Rosania; Madhuri Ramanathan; Carmen Montesinos; Marlene Jacobson; Michael A Schwarzschild; J Stephen Fink; Bruce N Cronstein
Synergistic up-regulation of vascular endothelial growth factor expression in murine macrophages by adenosine A(2A) receptor agonists and endotoxin.
The American journal of pathology 2002;160(6):2231-44.
2002: M Carmen Montesinos; Avani Desai; Jiang-Fan Chen; Herman Yee; Michael A Schwarzschild; J Stephen Fink; Bruce N Cronstein
Adenosine promotes wound healing and mediates angiogenesis in response to tissue injury via occupancy of A(2A) receptors.
The American journal of pathology 2002;160(6):2009-18.
2002: Michael A Schwarzschild; Jiang-Fan Chen; Alberto Ascherio
Caffeinated clues and the promise of adenosine A(2A) antagonists in PD.
Neurology 2002;58(8):1154-60.
2002: Kui Xu; Yue-Hang Xu; Jiang-Fan Chen; Michael A Schwarzschild
Caffeine's neuroprotection against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity shows no tolerance to chronic caffeine administration in mice.
Neuroscience letters 2002;322(1):13-6.
2002: Silva Fredduzzi; Rosario Moratalla; Angela Monopoli; Beatriz Cuellar; Kui Xu; Ennio Ongini; Francesco Impagnatiello; Michael A Schwarzschild; Jiang-Fan Chen
Persistent behavioral sensitization to chronic L-DOPA requires A2A adenosine receptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(3):1054-62.
2001: Tom Gearan; O A Castillo; Michael A Schwarzschild
The parkinsonian neurotoxin, MPP+ induces phosphorylated c-Jun in dopaminergric neurons of mesencephalic cultures.
Parkinsonism & related disorders 2001;8(1):19-22.
2001: Jiang-Fan Chen; Kui Xu; Jacobus P Petzer; Roland Staal; Yue-Hang Xu; MA Beilstein; Patricia K Sonsalla; Kay Castagnoli; Neal Castagnoli; Michael A Schwarzschild
Neuroprotection by caffeine and A(2A) adenosine receptor inactivation in a model of Parkinson's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(10):RC143.
2001: J M Armstrong; Jiang-Fan Chen; Michael A Schwarzschild; Sergey Apasov; Patrick T Smith; Charles C Caldwell; P Chen; H Figler; G Sullivan; S Fink; J Linden; Michail V Sitkovsky
Gene dose effect reveals no Gs-coupled A2A adenosine receptor reserve in murine T-lymphocytes: studies of cells from A2A-receptor-gene-deficient mice.
The Biochemical journal 2001;354(Pt 1):123-30.
2001: Jiang-Fan Chen; Rosario Moratalla; Francesco Impagnatiello; David K Grandy; Beatriz Cuellar; M Rubinstein; MA Beilstein; E Hackett; J Stephen Fink; Malcolm J Low; Ennio Ongini; Michael A Schwarzschild
The role of the D(2) dopamine receptor (D(2)R) in A(2A) adenosine receptor (A(2A)R)-mediated behavioral and cellular responses as revealed by A(2A) and D(2) receptor knockout mice.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(4):1970-5.
2000: György Haskó; David G Kuhel; J F Chen; Michael A Schwarzschild; Edwin A Deitch; Francisco Soriano; Anita Marton; Csaba Szabó
Adenosine inhibits IL-12 and TNF-[alpha] production via adenosine A2a receptor-dependent and independent mechanisms.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(13):2065-74.
2000: Sergey Apasov; Jiang-Fan Chen; Patrick T Smith; Michael A Schwarzschild; J Stephen Fink; Michail V Sitkovsky
Study of A(2A) adenosine receptor gene deficient mice reveals that adenosine analogue CGS 21680 possesses no A(2A) receptor-unrelated lymphotoxicity.
British journal of pharmacology 2000;131(1):43-50.
2000: Jonathan W Francis; Robert H Brown; Dayse Figueiredo; Mary P Remington; O Castillo; Michael A Schwarzschild; Paul S Fishman; John R Murphy; Johanna C vanderSpek
Enhancement of diphtheria toxin potency by replacement of the receptor binding domain with tetanus toxin C-fragment: a potential vector for delivering heterologous proteins to neurons.
Journal of neurochemistry 2000;74(6):2528-36.
2000: Jiang-Fan Chen; MA Beilstein; Yue-Hang Xu; T J Turner; Rosario Moratalla; David G Standaert; V J Aloyo; J Stephen Fink; Michael A Schwarzschild
Selective attenuation of psychostimulant-induced behavioral responses in mice lacking A(2A) adenosine receptors.
Neuroscience 2000;97(1):195-204.
1999: Jiang-Fan Chen; Z Huang; J Ma; J Zhu; Rosario Moratalla; David G Standaert; Michael A Moskowitz; J Stephen Fink; Michael A Schwarzschild
A(2A) adenosine receptor deficiency attenuates brain injury induced by transient focal ischemia in mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(21):9192-200.
1999: Michael A Schwarzschild; R L Cole; M A Meyers; Steven E Hyman
Contrasting calcium dependencies of SAPK and ERK activations by glutamate in cultured striatal neurons.
Journal of neurochemistry 1999;72(6):2248-55.
1997: Michael A Schwarzschild; R L Cole; Steven E Hyman
Glutamate, but not dopamine, stimulates stress-activated protein kinase and AP-1-mediated transcription in striatal neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(10):3455-66.
1997: Michael A Schwarzschild; Guy Rordorf; K Bekken; Ferdinando S Buonanno; Jeremy D Schmahmann
Normal-pressure hydrocephalus with misleading features of irreversible dementias: a case report.
Journal of geriatric psychiatry and neurology 1997;10(2):51-4.
1994: Michael A Schwarzschild; William T Dauer; S E Lewis; L K Hamill; J Stephen Fink; Steven E Hyman
Leukemia inhibitory factor and ciliary neurotrophic factor increase activated Ras in a neuroblastoma cell line and in sympathetic neuron cultures.
Journal of neurochemistry 1994;63(4):1246-54.
1991: Michael A Schwarzschild; Richard E Zigmond
Effects of peptides of the secretin-glucagon family and cyclic nucleotides on tyrosine hydroxylase activity in sympathetic nerve endings.
Journal of neurochemistry 1991;56(2):400-6.
1989: Michael A Schwarzschild; W Vale; A C Corigliano-Murphy; J J Pisano; N Y Ip; Richard E Zigmond
Activation of ganglionic tyrosine hydroxylase by peptides of the secretin-glucagon family: structure-function studies.
Neuroscience 1989;31(1):159-67.
1989: Richard E Zigmond; Michael A Schwarzschild; A R Rittenhouse
Acute regulation of tyrosine hydroxylase by nerve activity and by neurotransmitters via phosphorylation.
Annual review of neuroscience 1989;12():415-61.
1989: Michael A Schwarzschild; Richard E Zigmond
Secretin and vasoactive intestinal peptide activate tyrosine hydroxylase in sympathetic nerve endings.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1989;9(1):160-6.
1988: A R Rittenhouse; Michael A Schwarzschild; Richard E Zigmond
Both synaptic and antidromic stimulation of neurons in the rat superior cervical ganglion acutely increase tyrosine hydroxylase activity.
Neuroscience 1988;25(1):207-15.