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Robert Schwinger

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Ulrike Streit; Thorsten Wahlers; Wilhelm Bloch; Hannes Reuter; Robert H G Schwinger; Klara Brixius
Phosphorylation of myocardial eNOS is altered in patients suffering from type 2 diabetes.
Dennis Ladage; Robert H G Schwinger; Klara Brixius
Cardio-selective beta-blocker: pharmacological evidence and their influence on exercise capacity.
Zoltán Papp; John T Parissis; Alexander Parkhomenko; Piero Pollesello; Markku Salmenperä; Robert H G Schwinger; Bernt Gerhard Wikström; Mehmet Birhan Yilmaz; István Ferenc Édes; Sonja Fruhwald; Martín J García González; Elena Grossini; Fabio Guarracino; Kirsten Jörgensen; Matti Kivikko; Giovanni Landoni; Heli Leppikangas; Alexandre Mebazaa; Sven Meyer; Andrea Morelli; Lars Algotsson; Philippe Caimmi; Stefan G De Hert; Gerasimos Filippatos; Ferenc Follath
Levosimendan: molecular mechanisms and clinical implications: consensus of experts on the mechanisms of action of levosimendan.

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2013: Ulrike Streit; Thorsten Wahlers; Wilhelm Bloch; Hannes Reuter; Robert H G Schwinger; Klara Brixius
Phosphorylation of myocardial eNOS is altered in patients suffering from type 2 diabetes.
Journal of applied physiology (Bethesda, Md. : 1985) 2013;114(10):1366-74.
2013: Dennis Ladage; Robert H G Schwinger; Klara Brixius
Cardio-selective beta-blocker: pharmacological evidence and their influence on exercise capacity.
Cardiovascular therapeutics 2013;31(2):76-83.
2012: Zoltán Papp; John T Parissis; Alexander Parkhomenko; Piero Pollesello; Markku Salmenperä; Robert H G Schwinger; Bernt Gerhard Wikström; Mehmet Birhan Yilmaz; István Ferenc Édes; Sonja Fruhwald; Martín J García González; Elena Grossini; Fabio Guarracino; Kirsten Jörgensen; Matti Kivikko; Giovanni Landoni; Heli Leppikangas; Alexandre Mebazaa; Sven Meyer; Andrea Morelli; Lars Algotsson; Philippe Caimmi; Stefan G De Hert; Gerasimos Filippatos; Ferenc Follath
Levosimendan: molecular mechanisms and clinical implications: consensus of experts on the mechanisms of action of levosimendan.
International journal of cardiology 2012;159(2):82-7.
2012: Hannes Reuter; Robert H G Schwinger
Calcium handling in human heart failure--abnormalities and target for therapy.
Wiener medizinische Wochenschrift (1946) 2012;162(13-14):297-301.
2012: Obaida R Rana; Christopher Gemein; Malte Kelm; Julia S Kühnen; Nikolaus Marx; Christian Meyer; Esra Saygili; Patrick Schauerte; Johannes Schiefer; Jörg W Schröder; Robert H G Schwinger; Joachim Weis; Matthias D H Zink; Erol Saygili
The Modified Glasgow Outcome Score for the prediction of outcome in patients after cardiac arrest: a prospective clinical proof of concept study.
Clinical research in cardiology : official journal of the German Cardiac Society 2012;101(7):533-43.
2012: Erol Saygili; Robert H G Schwinger; Joachim Weis; Matthias D Zink; Christopher Gemein; Rahel Kluttig; Nikolaus Marx; Gediminas Rackauskas; Obaida R Rana; Esra Saygili; Patrick Schauerte
Age-related regional differences in cardiac nerve growth factor expression.
Age (Dordrecht, Netherlands) 2012;34(3):659-67.
2012: Jochen Müller-Ehmsen; Christof Scheid; Matthias Schmidt; Robert H G Schwinger; Paschalis Tossios; Nermin Unal; Axel Gossmann; Matthias Hackenbroch; Barbara Krug; Uwe Mehlhorn; Henning Bovenschulte; Erland Erdmann
Transmurality of scar influences the effect of a hybrid-intervention with autologous bone marrow cell injection and aortocoronary bypass surgery (MNC/CABG) in patients after myocardial infarction.
International journal of cardiology 2012;156(3):303-8.
2012: Erol Saygili; Robert H G Schwinger; Joachim Weis; Matthias D Zink; Christopher Gemein; Claudia Günzel; Nikolaus Marx; Karl Mischke; Fawad Noor-Ebad; Gediminas Rackauskas; Obaida R Rana; Esra Saygili; Patrick Schauerte
Rate and irregularity of electrical activation during atrial fibrillation affect myocardial NGF expression via different signalling routes.
Cellular signalling 2012;24(1):99-105.
2011: Eva Rieckeheer; Robert H G Schwinger; Wilhelm Bloch; Klara Brixius
Hawthorn special extract WS® 1442 increases red blood cell NO-formation without altering red blood cell deformability.
Phytomedicine : international journal of phytotherapy and phytopharmacology 2011;19(1):20-4.
2011: Erol Saygili; Patrick Schauerte; Robert H G Schwinger; Esra Saygili; Claudia Günzel; Nikolaus Marx; Karl Mischke; Fawad Noor-Ebad; Obaida R Rana
Irregular electrical activation of intrinsic cardiac adrenergic cells increases catecholamine-synthesizing enzymes.
Biochemical and biophysical research communications 2011;413(3):432-5.
2011: Esra Saygili; Esra Saygili; Patrick Schauerte; Robert H G Schwinger; Joachim Weis; Matthias D H Zink; Christopher Gemein; Dorothee Hommes; Nikolaus Marx; Fawad Noor-Ebad; Maimouna Pekassa; Gediminas Rackauskas; Obaida R Rana
Mechanical stretch of sympathetic neurons induces VEGF expression via a NGF and CNTF signaling pathway.
Biochemical and biophysical research communications 2011;410(1):62-7.
2011: Christian Brinkmann; Robert H G Schwinger; Klara Brixius
[Physical activity and endothelial dysfunction in type 2 diabetic patients: the role of nitric oxide and oxidative stress].
Wiener medizinische Wochenschrift (1946) 2011;161(11-12):305-14.
2011: Esra Saygili; Patrick Schauerte; Maimouna Pekassa; Esra Saygili; Gediminas Rackauskas; Robert H G Schwinger; Joachim Weis; Christian Weber; Nikolaus Marx; Obaida R Rana
Sympathetic neurons express and secrete MMP-2 and MT1-MMP to control nerve sprouting via pro-NGF conversion.
Cellular and molecular neurobiology 2011;31(1):17-25.
2010: Dennis Ladage; Christian Reidenbach; Eva Rieckeheer; Christine Graf; Robert H G Schwinger; Klara Brixius
Nebivolol lowers blood pressure and increases weight loss in patients with hypertension and diabetes in regard to age.
Journal of cardiovascular pharmacology 2010;56(3):275-81.
2010: Erol Saygili; Patrick Schauerte; Florian Küppers; Lutz Heck; Joachim Weis; Christian Weber; Robert H G Schwinger; Rainer Hoffmann; Jörg W Schröder; Nikolaus Marx; Obaida R Rana
Electrical stimulation of sympathetic neurons induces autocrine/paracrine effects of NGF mediated by TrkA.
Journal of molecular and cellular cardiology 2010;49(1):79-87.
2010: Obaida R Rana; Patrick Schauerte; Dorothee Hommes; Robert H G Schwinger; Jörg W Schröder; Rainer Hoffmann; Erol Saygili
Mechanical stretch induces nerve sprouting in rat sympathetic neurocytes.
Autonomic neuroscience : basic & clinical 2010;155(1-2):25-32.
2010: Oliver Rasp; Christian Paetzel; Walter Eichinger; Robert H G Schwinger
[Symptomatic pericardial cyst].
Medizinische Klinik (Munich, Germany : 1983) 2010;105(6):437-8.
2010: C Ruiz-Holst; Birgit Bölck; A Ghanem; K Tiemann; S Brokat; V Regitz-Zagrosek; Wilhelm Bloch; Robert H G Schwinger; Klara Brixius
eNOS phosphorylation and translocation are altered in male but not female mice by increased activation of the Gαq protein.
Canadian journal of physiology and pharmacology 2010;88(2):121-9.
2009: Christian Hauck; Tatjana Potter; Michaela Bartz; Thorsten Wittwer; Thorsten Wahlers; Uwe Mehlhorn; Georgios Scheiner-Bobis; Alicia A McDonough; Wilhelm Bloch; Robert H G Schwinger; Jochen Müller-Ehmsen
Isoform specificity of cardiac glycosides binding to human Na+,K+-ATPase alpha1beta1, alpha2beta1 and alpha3beta1.
European journal of pharmacology 2009;622(1-3):7-14.
2009: Erol Saygili; Obaida R Rana; Christian Meyer; Christopher Gemein; Michael G Andrzejewski; Andreas Ludwig; Christian Weber; Ulrich Schotten; Alexander Krüttgen; Joachim Weis; Robert H G Schwinger; Karl Mischke; Tienush Rassaf; Malte Kelm; Patrick Schauerte
The angiotensin-calcineurin-NFAT pathway mediates stretch-induced up-regulation of matrix metalloproteinases-2/-9 in atrial myocytes.
Basic research in cardiology 2009;104(4):435-48.
2009: Obaida R Rana; Erol Saygili; Christian Meyer; Christopher Gemein; Alexander Krüttgen; Michael G Andrzejewski; Andreas Ludwig; Ulrich Schotten; Robert H G Schwinger; Christian Weber; Joachim Weis; Karl Mischke; Tienush Rassaf; Malte Kelm; Patrick Schauerte
Regulation of nerve growth factor in the heart: the role of the calcineurin-NFAT pathway.
Journal of molecular and cellular cardiology 2009;46(4):568-78.
2009: Andreas Napp; Klara Brixius; Christian Pott; Christoph Ziskoven; Birgit Boelck; Uwe Mehlhorn; Robert H G Schwinger; Wilhelm Bloch
Effects of the beta3-adrenergic agonist BRL 37344 on endothelial nitric oxide synthase phosphorylation and force of contraction in human failing myocardium.
Journal of cardiac failure 2009;15(1):57-67.
2008: Paschalis Tossios; Benjamin Krausgrill; Matthias Schmidt; Thomas Fischer; Marcel Halbach; Jochen W U Fries; Silke Fahnenstich; Peter Frommolt; Ivonne Heppelmann; Annette Schmidt; Klaus Schomäcker; Jürgen H. Fischer; Wilhelm Bloch; Uwe Mehlhorn; Robert H G Schwinger; Jochen Müller-Ehmsen
Role of balloon occlusion for mononuclear bone marrow cell deposition after intracoronary injection in pigs with reperfused myocardial infarction.
European heart journal 2008;29(15):1911-21.
2008: Samuel Lee; Robert H G Schwinger; Klara Brixius
Genetically changed mice with chronic deficiency or overexpression of the beta-adrenoceptors--what can we learn for the therapy of heart failure?
Pflügers Archiv : European journal of physiology 2008;455(5):767-74.
2008: Voahanginirina Randriamboavonjy; Frank Pistrosch; Birgit Bölck; Robert H G Schwinger; Madhulika Dixit; Klaus Badenhoop; Richard A Cohen; Rudi Busse; Ingrid Fleming
Platelet sarcoplasmic endoplasmic reticulum Ca2+-ATPase and mu-calpain activity are altered in type 2 diabetes mellitus and restored by rosiglitazone.
Circulation 2008;117(1):52-60.
2008: Obaida R Rana; Carsten Zobel; Esra Saygili; Klara Brixius; Felix Gramley; Thomas Schimpf; Karl Mischke; Dirk Frechen; Christian Knackstedt; Robert H G Schwinger; Patrick Schauerte; Erol Saygili
A simple device to apply equibiaxial strain to cells cultured on flexible membranes.
American journal of physiology. Heart and circulatory physiology 2008;294(1):H532-40.
2008: Hannes Reuter; Sabine Grönke; Christian Adam; Maida Ribati; Jan Brabender; Carsten Zobel; Konrad Frank; Jens Wippermann; Robert H G Schwinger; Klara Brixius; Jochen Müller-Ehmsen
Sarcoplasmic Ca2+ release is prolonged in nonfailing myocardium of diabetic patients.
Molecular and cellular biochemistry 2008;308(1-2):141-9.
2007: Jan Schrickel; Klara Brixius; Claudia Herr; Christoph S Clemen; Philipp Sasse; Kathrin Reetz; Christian Grohé; Rainer Meyer; Klaus Tiemann; Rolf Schröder; Wilhelm Bloch; Georg Nickenig; Bernd K Fleischmann; Angelika A Noegel; Robert H G Schwinger; Thorsten Lewalter
Enhanced heterogeneity of myocardial conduction and severe cardiac electrical instability in annexin A7-deficient mice.
Cardiovascular research 2007;76(2):257-68.
2007: Franziska Grundmann; Christof Scheid; D Braun; Carsten Zobel; Hannes Reuter; Robert H G Schwinger; Jochen Müller-Ehmsen
Differential increase of CD34, KDR/CD34, CD133/CD34 and CD117/CD34 positive cells in peripheral blood of patients with acute myocardial infarction.
Clinical research in cardiology : official journal of the German Cardiac Society 2007;96(9):621-7.
2007: Klara Brixius; Robert H G Schwinger; Felix Hoyer; Andreas Napp; Robert Renner; Birgit Bölck; Angelika Kümin; Uwe Fischer; Uwe Mehlhorn; Sabine Werner; Wilhelm Bloch
Isoform-specific downregulation of peroxiredoxin in human failing myocardium.
Life sciences 2007;81(10):823-31.
2007: Klara Brixius; R Lu; Birgit Boelck; S Grafweg; Felix Hoyer; Christian Pott; Uwe Mehlhorn; Wilhelm Bloch; Robert H G Schwinger
Chronic treatment with carvedilol improves Ca(2+)-dependent ATP consumption in triton X-skinned fiber preparations of human myocardium.
The Journal of pharmacology and experimental therapeutics 2007;322(1):222-7.
2007: C Reidenbach; Robert H G Schwinger; Dirk Steinritz; Kai Kehe; Horst Thiermann; Theodor Klotz; Frank Sommer; Wilhelm Bloch; Klara Brixius
Nebivolol induces eNOS activation and NO-liberation in murine corpus cavernosum.
Life sciences 2007;80(26):2421-7.
2007: Esra Saygili; Obaida R Rana; Esra Saygili; Hannes Reuter; Konrad Frank; Robert H G Schwinger; Jochen Müller-Ehmsen; Carsten Zobel
Losartan prevents stretch-induced electrical remodeling in cultured atrial neonatal myocytes.
American journal of physiology. Heart and circulatory physiology 2007;292(6):H2898-905.
2007: Klara Brixius; M Middeke; A Lichtenthal; E Jahn; Robert H G Schwinger
Nitric oxide, erectile dysfunction and beta-blocker treatment (MR NOED study): benefit of nebivolol versus metoprolol in hypertensive men.
Clinical and experimental pharmacology & physiology 2007;34(4):327-31.
2007: Dennis Ladage; Klara Brixius; Caroline Steingen; Uwe Mehlhorn; Robert H G Schwinger; Wilhelm Bloch; Annette Schmidt
Mesenchymal stem cells induce endothelial activation via paracine mechanisms.
Endothelium : journal of endothelial cell research 2007;14(2):53-63.
2007: Carsten Zobel; Obaida R Rana; Esra Saygili; Birgit Bölck; Esra Saygili; Holger Diedrichs; Hannes Reuter; Konrad Frank; Jochen Müller-Ehmsen; Gabriele Pfitzer; Robert H G Schwinger
Mechanisms of Ca2+-dependent calcineurin activation in mechanical stretch-induced hypertrophy.
Cardiology 2007;107(4):281-90.
2007: Carsten Zobel; Persephone Zavidou-Saroti; Birgit Bölck; Klara Brixius; Hannes Reuter; Konrad Frank; Holger Diedrichs; Jochen Müller-Ehmsen; Wilhelm Bloch; Robert H G Schwinger
Altered tension cost in (TG(mREN-2)27) rats overexpressing the mouse renin gene.
European journal of applied physiology 2007;99(2):121-32.
2007: Christoph Ziskoven; Sabrina Grafweg; Birgit Bölck; Rudolf J Wiesner; Maria Jimenez; Jean-Paul Giacobino; Wilhelm Bloch; Robert H G Schwinger; Klara Brixius
Increased Ca2+ sensitivity and protein expression of SERCA 2a in situations of chronic beta3-adrenoceptor deficiency.
Pflügers Archiv : European journal of physiology 2007;453(4):443-53.
2006: Hannes Reuter; C Adam; S Grönke; Carsten Zobel; Konrad Frank; Jochen Müller-Ehmsen; Jan Brabender; Robert H G Schwinger
The increased angiotensin II (type 1) receptor density in myocardium of type 2 diabetic patients is prevented by blockade of the renin-angiotensin system.
Diabetologia 2006;49(12):3067-74.
2006: Jochen Müller-Ehmsen; Benjamin Krausgrill; Volker Burst; Kerstin Schenk; Uta C Neisen; Jochen W U Fries; Bernd K Fleischmann; Jürgen Hescheler; Robert H G Schwinger
Effective engraftment but poor mid-term persistence of mononuclear and mesenchymal bone marrow cells in acute and chronic rat myocardial infarction.
Journal of molecular and cellular cardiology 2006;41(5):876-84.
2006: Annette Schmidt; Dennis Ladage; Caroline Steingen; Klara Brixius; Timo Schinköthe; Franz-Josef Klinz; Robert H G Schwinger; Uwe Mehlhorn; Wilhelm Bloch
Mesenchymal stem cells transmigrate over the endothelial barrier.
European journal of cell biology 2006;85(11):1179-88.
2006: Norbert Frey; Klara Brixius; Robert H G Schwinger; Thomas Benis; Alex Karpowski; Hans P Lorenzen; Mark Luedde; Hugo A Katus; Wolfgang M Franz
Alterations of tension-dependent ATP utilization in a transgenic rat model of hypertrophic cardiomyopathy.
The Journal of biological chemistry 2006;281(40):29575-82.
2006: Klara Brixius; Wilhelm Bloch; Christoph Ziskoven; Birgit Bölck; Andreas Napp; Christian Pott; Dirk Steinritz; Maria Jiminez; Klaus Addicks; Jean-Paul Giacobino; Robert H G Schwinger
Beta3-adrenergic eNOS stimulation in left ventricular murine myocardium.
Canadian journal of physiology and pharmacology 2006;84(10):1051-60.
2006: Klara Brixius; Qiaofeng Song; Alock Malick; Birgit Boelck; Klaus Addicks; Wilhelm Bloch; Uwe Mehlhorn; Robert H G Schwinger
ENOS is not activated by nebivolol in human failing myocardium.
Life sciences 2006;79(13):1234-41.
2006: Christian Pott; Dirk Steinritz; Andreas Napp; Wilhelm Bloch; Robert H G Schwinger; Klara Brixius
[On the function of beta3-adrenoceptors in the human heart: signal transduction, inotropic effect and therapeutic prospects].
Wiener medizinische Wochenschrift (1946) 2006;156(15-16):451-8.
2006: Dennis Ladage; Klara Brixius; Heike Hoyer; Caroline Steingen; Andreas Wesseling; Daniela Malan; Wilhelm Bloch; Robert H G Schwinger
Mechanisms underlying nebivolol-induced endothelial nitric oxide synthase activation in human umbilical vein endothelial cells.
Clinical and experimental pharmacology & physiology 2006;33(8):720-4.
2006: Saeid Behmanesh; Paschalis Tossios; Hossam Homedan; Khosro Hekmat; Martin Hellmich; Jochen Müller-Ehmsen; Robert H G Schwinger; Uwe Mehlhorn
Effect of prophylactic bisoprolol plus magnesium on the incidence of atrial fibrillation after coronary bypass surgery: results of a randomized controlled trial.
Current medical research and opinion 2006;22(8):1443-50.
2006: Annette Schmidt; Dennis Ladage; Timo Schinköthe; Ursula Klausmann; Christoph Ulrichs; Franz-Josef Klinz; Klara Brixius; Stefan Arnhold; Biren Desai; Uwe Mehlhorn; Robert H G Schwinger; Peter Staib; Klaus Addicks; Wilhelm Bloch
Basic fibroblast growth factor controls migration in human mesenchymal stem cells.
Stem cells (Dayton, Ohio) 2006;24(7):1750-8.
2006: Hans J Geissler; Uwe M Fischer; Stephanie Grunert; Ferdinand Kuhn-Régnier; Arnulf Hoelscher; Robert H G Schwinger; Uwe Mehlhorn; Khosro Hekmat
Incidence and outcome of gastrointestinal complications after cardiopulmonary bypass.
Interactive cardiovascular and thoracic surgery 2006;5(3):239-42.
2006: Klara Brixius; Sonja Willms; Andreas Napp; Paschalis Tossios; Dennis Ladage; Wilhelm Bloch; Uwe Mehlhorn; Robert H G Schwinger
Crataegus special extract WS 1442 induces an endothelium-dependent, NO-mediated vasorelaxation via eNOS-phosphorylation at serine 1177.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 2006;20(3):177-84.
2006: Christian Pott; Dirk Steinritz; Birgit Bölck; Uwe Mehlhorn; Klara Brixius; Robert H G Schwinger; Wilhelm Bloch
eNOS translocation but not eNOS phosphorylation is dependent on intracellular Ca2+ in human atrial myocardium.
American journal of physiology. Cell physiology 2006;290(5):C1437-45.
2006: Klara Brixius; Konrad Frank; Birgit Bölck; Felix Hoyer; Robert H G Schwinger
[Reverse remodeling of the intracellular Ca(2+)-homeostasis: new concepts of pathophysiology and therapy of heart failure].
Wiener medizinische Wochenschrift (1946) 2006;156(7-8):209-15.
2006: Christian Pott; Klara Brixius; Wilhelm Bloch; Christoph Ziskoven; Andreas Napp; Robert H G Schwinger
Beta3-adrenergic stimulation in the human heart: signal transduction, functional implications and therapeutic perspectives.
Die Pharmazie 2006;61(4):255-60.
2006: Benjamin Krausgrill; Robert H G Schwinger; Jochen Müller-Ehmsen
[Mesenchymal stem cells for cardiac regeneration].
Medizinische Klinik (Munich, Germany : 1983) 2006;101 Suppl 1():202-6.
2006: Carsten Zobel; Robert H G Schwinger
[Therapy of heart failure in the elderly].
Medizinische Klinik (Munich, Germany : 1983) 2006;101 Suppl 1():47-50.
2006: Stephan Rosenkranz; Klara Brixius; René Halbach; Holger Diedrichs; Robert H G Schwinger
Phosphodiesterase type 5 inhibitor sildenafil citrate does not potentiate the vasodilative properties of nebivolol in rat aorta.
Life sciences 2006;78(10):1103-7.
2006: Paschalis Tossios; Jochen Müller-Ehmsen; Matthias Schmidt; Christof Scheid; Nermin Unal; Detlef Moka; Robert H G Schwinger; Uwe Mehlhorn
No evidence of myocardial restoration following transplantation of mononuclear bone marrow cells in coronary bypass grafting surgery patients based upon cardiac SPECT and 18F-PET.
BMC medical imaging 2006;6():7.
2006: Holger M Nef; Helge Möllmann; Woitek Skwara; Birgit Bölck; Robert H G Schwinger; Ch Hamm; Sawa Kostin; Jutta Schaper; Albrecht Elsässer
Reduced sarcoplasmic reticulum Ca2+ -ATPase activity and dephosphorylated phospholamban contribute to contractile dysfunction in human hibernating myocardium.
Molecular and cellular biochemistry 2006;282(1-2):53-63.
2006: Jochen Müller-Ehmsen; Annette Schmidt; Benjamin Krausgrill; Robert H G Schwinger; Wilhelm Bloch
Role of erythropoietin for angiogenesis and vasculogenesis: from embryonic development through adulthood.
American journal of physiology. Heart and circulatory physiology 2006;290(1):H331-40.
2005: Klara Brixius; Heike Katharina Hoyer; Robert H G Schwinger
Ca2+-sensitisers--a promising option to treat heart failure?
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 2005;19(6):423-8.
2005: Khosro Hekmat; A Raabe; Axel Kroener; Uwe M Fischer; Michael Suedkamp; Hans J Geissler; Robert H G Schwinger; Sandra Kampe; Uwe Mehlhorn
Risk stratification models fail to predict hospital costs of cardiac surgery patients.
Zeitschrift für Kardiologie 2005;94(11):748-53.
2005: Jens Hagemeister; Frank M Baer; Robert H G Schwinger; Hans W Höpp
Compliance of a cobalt chromium coronary stent alloy--the COVIS trial.
Current controlled trials in cardiovascular medicine 2005;6():17.
2005: Franz-Josef Klinz; Annette Schmidt; Timo Schinköthe; Stefan Arnhold; Biren Desai; Frank Popken; Klara Brixius; Robert H G Schwinger; Uwe Mehlhorn; Peter Staib; Klaus Addicks; Wilhelm Bloch
Phospho-eNOS Ser-114 in human mesenchymal stem cells: constitutive phosphorylation, nuclear localization and upregulation during mitosis.
European journal of cell biology 2005;84(10):809-18.
2005: Klara Brixius; Thomas Gross; Paschalis Tossios; Hans J Geissler; Uwe Mehlhorn; Robert H G Schwinger; Khosro Hekmat
Increased vascular selectivity and prolonged pharmacological efficacy of the L-type Ca2+ channel antagonist lercanidipine in human cardiovascular tissue.
Clinical and experimental pharmacology & physiology 2005;32(9):708-13.
2005: Jochen Müller-Ehmsen; Christof Scheid; Franziska Grundmann; Ingo Hirsch; Gökmen Turan; Paschalis Tossios; Uwe Mehlhorn; Robert H G Schwinger
The mobilization of CD34 positive mononuclear cells after myocardial infarction is abolished by revascularization of the culprit vessel.
International journal of cardiology 2005;103(1):7-11.
2005: Hannes Reuter; Christian Pott; Joshua I Goldhaber; Scott A Henderson; Kenneth D Philipson; Robert H G Schwinger
Na(+)--Ca2+ exchange in the regulation of cardiac excitation-contraction coupling.
Cardiovascular research 2005;67(2):198-207.
2005: Jochen Müller-Ehmsen; Franziska Grundmann; Robert H G Schwinger; Timo Schinköthe
Letters regarding article by Wojakowski et al, "mobilization of CD34/CXCR4+, CD34/CD117+, c-met+ stem cells, and mononuclear cells expressing early cardiac, muscle, and endothelial markers into peripheral blood in patients with acute myocardial infarction".
Circulation 2005;111(20):e307; author reply e307-8.
2005: Holger Diedrichs; Carsten Zobel; Peter Theissen; Michael Weber; Athanassios Koulousakis; Harald Schicha; Robert H G Schwinger
Symptomatic relief precedes improvement of myocardial blood flow in patients under spinal cord stimulation.
Current controlled trials in cardiovascular medicine 2005;6(1):7.
2005: Khosro Hekmat; Axel Kroener; Hartmut Stuetzer; Robert H G Schwinger; Sandra Kampe; Ger B W E Bennink; Uwe Mehlhorn
Daily assessment of organ dysfunction and survival in intensive care unit cardiac surgical patients.
The Annals of thoracic surgery 2005;79(5):1555-62.
2005: Natali B Bauer; Jochen Müller-Ehmsen; Ulrike Krämer; Njde Hambarchian; Carsten Zobel; Robert H G Schwinger; Horst Neu; Ulrike Kirch; Ernst-Günther Grünbaum; Wilhelm Schoner
Ouabain-like compound changes rapidly on physical exercise in humans and dogs: effects of beta-blockade and angiotensin-converting enzyme inhibition.
Hypertension 2005;45(5):1024-8.
2005: Robert H G Schwinger; Klara Brixius
[If the myofilaments become sensitive: Ca2+-sensitizer for the therapy of heart insufficiency].
Deutsche medizinische Wochenschrift (1946) 2005;130(15):969-73.
2005: S Grönke; Matthias Schmidt; Robert H G Schwinger
[Typical angina pectoris complaints without coronary macroangiopathy].
Deutsche medizinische Wochenschrift (1946) 2005;130(15):942-5.
2005: Konrad Frank; Birgit Bölck; Z Ding; D Krause; N Hattebuhr; A Malik; Klara Brixius; R J Hajjar; J Schrader; Robert H G Schwinger
Overexpression of sorcin enhances cardiac contractility in vivo and in vitro.
Journal of molecular and cellular cardiology 2005;38(4):607-15.
2005: Klara Brixius; Sonja Willms; Robert H G Schwinger
[The basis for treatment of cardiovascular diseases: cellular and molecular mechanisms of Crataegus extract].
Pharmazie in unserer Zeit 2005;34(1):48-51.
2005: Klara Brixius; Hannes Reuter; Wilhelm Bloch; Robert H G Schwinger
Altered hetero- and homeometric autoregulation in the terminally failing human heart.
European journal of heart failure 2005;7(1):29-35.
2004: Carsten Zobel; Hannes Reuter; Robert H G Schwinger
[Treatment of cardiogenic shock with the Ca2+ sensitizer levosimendan].
Medizinische Klinik (Munich, Germany : 1983) 2004;99(12):742-6.
2004: Klara Brixius; Wilhelm Bloch; Christian Pott; Andreas Napp; Andreas Krahwinkel; Christoph Ziskoven; Marco Koriller; Uwe Mehlhorn; Jürgen Hescheler; Bernd K Fleischmann; Robert H G Schwinger
Mechanisms of beta 3-adrenoceptor-induced eNOS activation in right atrial and left ventricular human myocardium.
British journal of pharmacology 2004;143(8):1014-22.
2004: Holger Diedrichs; C Mei; Konrad Frank; Birgit Boelck; Robert H G Schwinger
Calcineurin independent development of myocardial hypertrophy in transgenic rats overexpressing the mouse renin gene, TGR(mREN2)27.
Journal of molecular medicine (Berlin, Germany) 2004;82(10):688-95.
2004: Birgit Bölck; Götz Münch; Peter Mackenstein; Martin Hellmich; Ingo Hirsch; Hannes Reuter; Nadja Hattebuhr; Hans-Jörg Weig; Martin Ungerer; Klara Brixius; Robert H G Schwinger
Na+/Ca2+ exchanger overexpression impairs frequency- and ouabain-dependent cell shortening in adult rat cardiomyocytes.
American journal of physiology. Heart and circulatory physiology 2004;287(4):H1435-45.
2004: Khosro Hekmat; C Menzel; Axel Kroener; Robert H G Schwinger; Sandra Kampe; Uwe M Fischer; Hans J Geissler; Uwe Mehlhorn
The effect of preoperative antiplatelet therapy in coronary artery surgery: blood transfusion requirements for patients on cardiopulmonary bypass.
Current medical research and opinion 2004;20(9):1429-35.
2004: Khosro Hekmat; B Salemink; G Lauterbach; Robert H G Schwinger; Michael Südkamp; H J Weber; Uwe Mehlhorn
Interference by cellular phones with permanent implanted pacemakers: an update.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2004;6(4):363-9.
2004: Jochen Müller-Ehmsen; Robert H G Schwinger
TNF and congestive heart failure: therapeutic possibilities.
Expert opinion on therapeutic targets 2004;8(3):203-9.
2004: Njde Hambarchian; Klara Brixius; Rong Lu; Jochen Müller-Ehmsen; Robert H G Schwinger
Ouabain increases myofibrillar Ca2+ sensitivity but does not influence the Ca2+ release in human skinned fibres.
European journal of pharmacology 2004;492(2-3):225-31.
2004: Andreas Bundkirchen; Klara Brixius; Robert H G Schwinger
[Beta-adrenoceptor antagonists in the treatment of chronic heart failure].
Die Pharmazie 2004;59(2):83-92.
2004: Jan Matthes; Andreas Jäger; Renate Handrock; Ferdi Groner; Uwe Mehlhorn; Robert H G Schwinger; Gyula Varadi; Arnold Schwartz; Stefan Herzig
Ca2+-dependent modulation of single human cardiac L-type calcium channels by the calcineurin inhibitor cyclosporine.
Journal of molecular and cellular cardiology 2004;36(2):241-55.
2004: Holger Diedrichs; Mei Chi; Birgit Boelck; Uwe Mehlhorn; Uwe Mehlhorm; Robert H G Schwinger
Increased regulatory activity of the calcineurin/NFAT pathway in human heart failure.
European journal of heart failure 2004;6(1):3-9.
2003: Klara Brixius; Annette Wollmer; Birgit Bölck; Uwe Mehlhorn; Robert H G Schwinger
Ser16-, but not Thr17-phosphorylation of phospholamban influences frequency-dependent force generation in human myocardium.
Pflügers Archiv : European journal of physiology 2003;447(2):150-7.
2003: Frank Callies; Hinrik Strömer; Robert H G Schwinger; Birgit Bölck; Kai Hu; Stefan Frantz; Andrea Leupold; Stephanie Beer; Bruno Allolio; Andreas W Bonz
Administration of testosterone is associated with a reduced susceptibility to myocardial ischemia.
Endocrinology 2003;144(10):4478-83.
2003: Andreas Bundkirchen; Quang Nguyen; Klara Brixius; Birgit Bölck; Uwe Mehlhorn; Robert H G Schwinger
Lack of inverse agonistic activity of nebivolol, its D- and L-enantiomers and of in vivo metabolized nebivolol in human myocardium.
European journal of pharmacology 2003;476(1-2):97-105.
2003: Klara Brixius; Persephone Savidou-Zaroti; Wilhelm Bloch; Robert H G Schwinger
Reduced length-dependent cross-bridge recruitment in skinned fiber preparations of human failing myocardium.
European journal of applied physiology 2003;89(3-4):249-56.
2003: Robert H G Schwinger; Konrad Frank
Calcium and the failing heart: phospholamban, good guy or bad guy?
Science's STKE : signal transduction knowledge environment 2003;2003(180):pe15.
2003: Jochen Müller-Ehmsen; Robert H G Schwinger
[Therapeutic perspectives in heart failure]].
Zeitschrift für ärztliche Fortbildung und Qualitätssicherung 2003;97(2):127-32.
2003: Wilhelm Schoner; Natali B Bauer; Jochen Müller-Ehmsen; Ulrike Krämer; Njde Hambarchian; Robert H G Schwinger; Hans Moeller; Holger Kost; Christine Weitkamp; Thomas Schweitzer; Ulrike Kirch; Horst Neu; Ernst-Günther Grünbaum
Ouabain as a mammalian hormone.
Annals of the New York Academy of Sciences 2003;986():678-84.
2003: Robert H G Schwinger; Henning Bundgaard; Jochen Müller-Ehmsen; Keld Kjeldsen
The Na, K-ATPase in the failing human heart.
Cardiovascular research 2003;57(4):913-20.
2003: Holger Diedrichs; Michael Weber; Eberhard Voth; Atanasios Koulousakis; Carsten Zobel; Robert H G Schwinger
[Increased myocardial blood flow after spinal cord stimulation in patients with refractory angina pectoris].
Medizinische Klinik (Munich, Germany : 1983) 2003;98(3):146-50.
2003: Jochen Müller-Ehmsen; Johanna Nickel; Carsten Zobel; Ingo Hirsch; Birgit Bölck; Klara Brixius; Robert H G Schwinger
Longer term effects of ouabain on the contractility of rat isolated cardiomyocytes and on the expression of Ca and Na regulating proteins.
Basic research in cardiology 2003;98(2):90-6.
2003: Christian Pott; Klara Brixius; Andreas Bundkirchen; Birgit Bölck; Wilhelm Bloch; Dirk Steinritz; Uwe Mehlhorn; Robert H G Schwinger
The preferential beta3-adrenoceptor agonist BRL 37344 increases force via beta1-/beta2-adrenoceptors and induces endothelial nitric oxide synthase via beta3-adrenoceptors in human atrial myocardium.
British journal of pharmacology 2003;138(3):521-9.
2003: Andreas Bundkirchen; Klara Brixius; Birgit Bölck; Quang Nguyen; Robert H G Schwinger
Beta 1-adrenoceptor selectivity of nebivolol and bisoprolol. A comparison of [3H]CGP 12.177 and [125I]iodocyanopindolol binding studies.
European journal of pharmacology 2003;460(1):19-26.
2003: Konrad Frank; Birgit Bölck; Erland Erdmann; Robert H G Schwinger
Sarcoplasmic reticulum Ca2+-ATPase modulates cardiac contraction and relaxation.
Cardiovascular research 2003;57(1):20-7.
2002: D H Antoni; D Beuckelmann; Rainer Hambrecht; F Nowak; D Schuchert; Robert H G Schwinger
[Treatment of chronic heart failure with beta-adrenoceptor antagonists. Guideline-based optimization with ERICA, a quality register].
Deutsche medizinische Wochenschrift (1946) 2002;127(46):2459-63.
2002: Jochen Müller-Ehmsen; Larry Kedes; Robert H G Schwinger; Robert A Kloner
Cellular cardiomyoplasty--a novel approach to treat heart disease.
Congestive heart failure (Greenwich, Conn.) 2002;8(4):220-7.
2002: Klara Brixius; S Reicke; H Reuter; Robert H G Schwinger
Effects of the Ca2+ sensitizers EMD 57033 and CGP 48506 on myocardial contractility and Ca2+ transients in human ventricular and atrial myocardium.
Zeitschrift für Kardiologie 2002;91(4):312-8.
2002: Robert H G Schwinger
[Treatment of heart failure with beta-receptor-blockers].
Deutsche medizinische Wochenschrift (1946) 2002;127(13):682-8.
2002: Götz Münch; Birgit Bölck; Peter Karczewski; Robert H G Schwinger
Evidence for calcineurin-mediated regulation of SERCA 2a activity in human myocardium.
Journal of molecular and cellular cardiology 2002;34(3):321-34.
2002: Andreas Bundkirchen; Klara Brixius; Birgit Bölck; Robert H G Schwinger
Bucindolol exerts agonistic activity on the propranolol-insensitive state of beta1-adrenoceptors in human myocardium.
The Journal of pharmacology and experimental therapeutics 2002;300(3):794-801.
2002: Robert Stehle; Martina Krüger; Peter Scherer; Klara Brixius; Robert H G Schwinger; Gabriele Pfitzer
Isometric force kinetics upon rapid activation and relaxation of mouse, guinea pig and human heart muscle studied on the subcellular myofibrillar level.
Basic research in cardiology 2002;97 Suppl 1():I127-35.
2002: Klara Brixius; Persephone Savvidou-Zaroti; Uwe Mehlhorn; Wilhelm Bloch; Evangelia G Kranias; Robert H G Schwinger
Increased Ca2+-sensitivity of myofibrillar tension in heart failure and its functional implication.
Basic research in cardiology 2002;97 Suppl 1():I111-7.
2002: Konrad Frank; Birgit Bölck; Klara Brixius; Evangelia G Kranias; Robert H G Schwinger
Modulation of SERCA: implications for the failing human heart.
Basic research in cardiology 2002;97 Suppl 1():I72-8.
2002: Jochen Müller-Ehmsen; Alicia A McDonough; Robert A Farley; Robert H G Schwinger
Sodium pump isoform expression in heart failure: implication for treatment.
Basic research in cardiology 2002;97 Suppl 1():I25-30.
2002: Alicia A McDonough; Jeffrey B Velotta; Robert H G Schwinger; Kenneth D Philipson; Robert A Farley
The cardiac sodium pump: structure and function.
Basic research in cardiology 2002;97 Suppl 1():I19-24.
2002: Robert H G Schwinger
Calcium and the failing heart.
Basic research in cardiology 2002;97 Suppl 1():I1-3.
2002: Klara Brixius; Sebastian Reicke; Robert H G Schwinger
Beneficial effects of the Ca(2+) sensitizer levosimendan in human myocardium.
American journal of physiology. Heart and circulatory physiology 2002;282(1):H131-7.
2001: Klara Brixius; S Hoischen; Hannes Reuter; Kathrin Lasek; Robert H G Schwinger
Force/shortening-frequency relationship in multicellular muscle strips and single cardiomyocytes of human failing and nonfailing hearts.
Journal of cardiac failure 2001;7(4):335-41.
2001: Jochen Müller-Ehmsen; P Juvvadi; Curtis B Thompson; L Tumyan; Mickey Croyle; J B Lingrel; Robert H G Schwinger; Alicia A McDonough; Robert A Farley
Ouabain and substrate affinities of human Na(+)-K(+)-ATPase alpha(1)beta(1), alpha(2)beta(1), and alpha(3)beta(1) when expressed separately in yeast cells.
American journal of physiology. Cell physiology 2001;281(4):C1355-64.
2001: Klara Brixius; Andreas Bundkirchen; Birgit Bölck; Uwe Mehlhorn; Robert H G Schwinger
Nebivolol, bucindolol, metoprolol and carvedilol are devoid of intrinsic sympathomimetic activity in human myocardium.
British journal of pharmacology 2001;133(8):1330-8.
2001: Claudia Herr; Neil Smyth; Susanne Ullrich; F Yun; Philipp Sasse; Jürgen Hescheler; Bernd K Fleischmann; Kathrin Lasek; Klara Brixius; Robert H G Schwinger; Reinhard Fässler; Rolf Schröder; Angelika A Noegel
Loss of annexin A7 leads to alterations in frequency-induced shortening of isolated murine cardiomyocytes.
Molecular and cellular biology 2001;21(13):4119-28.
2001: Andreas Bundkirchen; Klara Brixius; Birgit Bölck; Uwe Mehlhorn; Wilhelm Bloch; Robert H G Schwinger
Nebivolol, carvedilol and metoprolol do not influence cardiac Ca(2+) sensitivity.
European journal of pharmacology 2001;422(1-3):175-80.
2001: Götz Münch; Birgit Bölck; A Sugaru; Klara Brixius; Wilhelm Bloch; Robert H G Schwinger
Increased expression of isoform 1 of the sarcoplasmic reticulum Ca(2+)-release channel in failing human heart.
Circulation 2001;103(22):2739-44.
2001: Klara Brixius; S Hoischen; Carsten Zobel; Kathrin Lasek; Robert H G Schwinger
[The Ca(2+) sensitizers CGP 48506 and EMD 57033, but not the Na(+) channel modulator BDF 9148, prolong relaxation in isolated cardiomyocytes of the guinea pig].
Zeitschrift für Kardiologie 2001;90(4):286-91.
2001: Jochen Müller-Ehmsen; J Wang; Robert H G Schwinger; Alicia A McDonough
Region specific regulation of sodium pump isoform and Na,Ca-exchanger expression in the failing human heart--right atrium vs left ventricle.
Cellular and molecular biology (Noisy-le-Grand, France) 2001;47(2):373-81.
2001: Carsten Zobel; Holger Diedrichs; HJ Deutsch; Robert H G Schwinger
[Epidural spinal cord stimulation in the treatment of therapy-resistant angina pectoris].
Deutsche medizinische Wochenschrift (1946) 2001;126(7):180-3.
2000: Klara Brixius; Uwe Mehlhorn; Wilhelm Bloch; Robert H G Schwinger
Different effect of the Ca(2+) sensitizers EMD 57033 and CGP 48506 on cross-bridge cycling in human myocardium.
The Journal of pharmacology and experimental therapeutics 2000;295(3):1284-90.
2000: Carsten Zobel; Klara Brixius; Birgit Bölck; Konrad Frank; Robert H G Schwinger
Diminished posttetanic potentiation in failing human myocardium.
Basic research in cardiology 2000;95(5):349-58.
2000: Götz Münch; Birgit Bölck; Klara Brixius; Hannes Reuter; Uwe Mehlhorn; Wilhelm Bloch; Robert H G Schwinger
SERCA2a activity correlates with the force-frequency relationship in human myocardium.
American journal of physiology. Heart and circulatory physiology 2000;278(6):H1924-32.
2000: Robert H G Schwinger
[Chronic heart failure. Diagnosis and therapy].
Medizinische Monatsschrift für Pharmazeuten 2000;23(5):142-8.
2000: Robert H G Schwinger; M Pietsch; Konrad Frank; Klara Brixius
Crataegus special extract WS 1442 increases force of contraction in human myocardium cAMP-independently.
Journal of cardiovascular pharmacology 2000;35(5):700-7.
2000: Robert H G Schwinger
[Role of nitrates in the treatment of ischemia].
Deutsche medizinische Wochenschrift (1946) 2000;125 Suppl 1():S6.
2000: Klara Brixius; Robert H G Schwinger
Modulation of cross-bridge interaction by 2,3-butanedione monoxime in human ventricular myocardium.
Naunyn-Schmiedeberg's archives of pharmacology 2000;361(4):440-4.
2000: Robert H G Schwinger; Klara Brixius; Persephone Savvidou-Zaroti; Birgit Bölck; Carsten Zobel; Konrad Frank; Evangelia G Kranias; S Hoischen; Erland Erdmann
The enhanced contractility in phospholamban deficient mouse hearts is not associated with alterations in (Ca2+)-sensitivity or myosin ATPase-activity of the contractile proteins.
Basic research in cardiology 2000;95(1):12-8.
2000: Carsten Zobel; HJ Deutsch; Robert H G Schwinger; Erland Erdmann
[Peripartal cardiomyopathy--its pathophysiology, diagnosis and current therapy].
Deutsche medizinische Wochenschrift (1946) 2000;125(4):90-4.
2000: Götz Münch; Birgit Bölck; A Sugaru; Robert H G Schwinger
Isoform expression of the sarcoplasmic reticulum Ca2+ release channel (ryanodine channel) in human myocardium.
Journal of molecular medicine (Berlin, Germany) 2000;78(6):352-60.
1999: Robert H G Schwinger
[Value of diuretics and aldosterone antagonists in the treatment of heart failure].
Deutsche medizinische Wochenschrift (1946) 1999;124 Suppl 2():S40-7.
1999: Hannes Reuter; Carsten Zobel; Klara Brixius; Birgit Bölck; Robert H G Schwinger
The force-frequency relationship is dependent on Ca(2+)-influx via L-type- and SR-Ca(2+)-channels in human heart.
Basic research in cardiology 1999;94(3):159-70.
1999: Klara Brixius; M Pietsch; Robert H G Schwinger
The intracellular Ca(2+)-homeostasis influences the frequency-dependent force-generation in man.
Basic research in cardiology 1999;94(3):152-8.
1999: Robert H G Schwinger; J Wang; Konrad Frank; Jochen Müller-Ehmsen; Klara Brixius; Alicia A McDonough; Erland Erdmann
Reduced sodium pump alpha1, alpha3, and beta1-isoform protein levels and Na+,K+-ATPase activity but unchanged Na+-Ca2+ exchanger protein levels in human heart failure.
Circulation 1999;99(16):2105-12.
1999: Robert H G Schwinger; Götz Münch; Birgit Bölck; Peter Karczewski; Ernst-Georg Krause; Erland Erdmann
Reduced Ca(2+)-sensitivity of SERCA 2a in failing human myocardium due to reduced serin-16 phospholamban phosphorylation.
Journal of molecular and cellular cardiology 1999;31(3):479-91.
1999: Robert H G Schwinger; S Hoischen; Hannes Reuter; Roger Hullin
Regional expression and functional characterization of the L-type Ca2+-channel in myocardium from patients with end-stage heart failure and in non-failing human hearts.
Journal of molecular and cellular cardiology 1999;31(1):283-96.
1999: Jochen Müller-Ehmsen; M Näbauer; Robert H G Schwinger
Na+-channel modulating effect of the inotropic compound S(-)BDF 9196 in human myocardium.
Naunyn-Schmiedeberg's archives of pharmacology 1999;359(1):60-4.
1998: Konrad Frank; Birgit Bölck; U Bavendiek; Robert H G Schwinger
Frequency dependent force generation correlates with sarcoplasmic calcium ATPase activity in human myocardium.
Basic research in cardiology 1998;93(5):405-11.
1998: Robert H G Schwinger; Birgit Bölck; G Münch; Klara Brixius; Jochen Müller-Ehmsen; E Erdmann
cAMP-dependent protein kinase A-stimulated sarcoplasmic reticulum function in heart failure.
Annals of the New York Academy of Sciences 1998;853():240-50.
1998: F Schröder; Renate Handrock; Dirk J Beuckelmann; Stephan Hirt; Roger Hullin; L Priebe; Robert H G Schwinger; J Weil; Stefan Herzig
Increased availability and open probability of single L-type calcium channels from failing compared with nonfailing human ventricle.
Circulation 1998;98(10):969-76.
1998: Klara Brixius; V Mohr; Jochen Müller-Ehmsen; S Hoischen; Götz Münch; Robert H G Schwinger
Potent vasodilatory with minor cardiodepressant actions of mibefradil in human cardiac tissue.
British journal of pharmacology 1998;125(1):41-8.
1998: S Hoischen; Klara Brixius; Robert H G Schwinger
T- and L-type Ca2+-channel antagonists reduce contractility in guinea pig cardiac myocytes.
Journal of cardiovascular pharmacology 1998;32(2):323-30.
1998: Carsten Zobel; Klara Brixius; M Pietsch; Götz Münch; Birgit Bölck; Robert H G Schwinger
Unchanged sarcoplasmic reticulum Ca2+-ATPase activity, reduced Ca2+ sensitivity, and negative force-frequency relationship in transgenic rats overexpressing the mouse renin gene.
Journal of molecular medicine (Berlin, Germany) 1998;76(7):533-44.
1998: Carsten Zobel; Klara Brixius; Konrad Frank; Robert H G Schwinger
Effect of the Na+-channel modulator BDF 9148 on Ca2+-sensitivity and force of contraction of hypertrophic myocardium from transgene rats harboring the mouse Renin gene (TG(mREN2)27).
Naunyn-Schmiedeberg's archives of pharmacology 1998;357(5):532-9.
1998: Götz Münch; Birgit Bölck; S Hoischen; Klara Brixius; W Bloch; Hannes Reuter; Robert H G Schwinger
Unchanged protein expression of sarcoplasmic reticulum Ca2+-ATPase, phospholamban, and calsequestrin in terminally failing human myocardium.
Journal of molecular medicine (Berlin, Germany) 1998;76(6):434-41.
1998: Jochen Müller-Ehmsen; Klara Brixius; Robert H G Schwinger
Positive inotropic effects of the novel Na+-channel modulator BDF 9198 in human nonfailing and failing myocardium.
Journal of cardiovascular pharmacology 1998;31(5):684-9.
1998: U Bavendiek; Klara Brixius; Götz Münch; Carsten Zobel; Jochen Müller-Ehmsen; Robert H G Schwinger
Effect of inotropic interventions on the force-frequency relation in the human heart.
Basic research in cardiology 1998;93 Suppl 1():76-85.
1997: Robert H G Schwinger; Klara Brixius; U Bavendiek; S Hoischen; Jochen Müller-Ehmsen; Birgit Bölck; Erland Erdmann
Effect of cyclopiazonic acid on the force-frequency relationship in human nonfailing myocardium.
The Journal of pharmacology and experimental therapeutics 1997;283(1):286-92.
1997: Klara Brixius; M Pietsch; S Hoischen; Jochen Müller-Ehmsen; Robert H G Schwinger
Effect of inotropic interventions on contraction and Ca2+ transients in the human heart.
Journal of applied physiology (Bethesda, Md. : 1985) 1997;83(2):652-60.
1997: Robert H G Schwinger; Konrad Frank; S Hoischen; Jochen Müller-Ehmsen; Klara Brixius
[Effect of changed extracellular K(+) and Mg(2+)-concentration on intracellular Ca(2+) homeostasis, contraction coupling and force-frequency relations in the human myocardium].
Herz 1997;22 Suppl 1():18-27.
1997: Jochen Müller-Ehmsen; Klara Brixius; C Schulze; Robert H G Schwinger
Na+ channel modulation and force-frequency relationship in human myocardium.
Naunyn-Schmiedeberg's archives of pharmacology 1997;355(6):727-32.
1997: Jochen Müller-Ehmsen; Konrad Frank; Klara Brixius; Robert H G Schwinger
Increase in force of contraction by activation of the Na+/Ca(2+)-exchanger in human myocardium.
British journal of clinical pharmacology 1997;43(4):399-405.
1996: Jochen Müller-Ehmsen; Klara Brixius; S Hoischen; Robert H G Schwinger
Inotropic and coronary vasodilatory actions of the K-adenosine triphosphate channel modulator nicorandil in human tissue.
The Journal of pharmacology and experimental therapeutics 1996;279(3):1220-8.
1996: J Wang; Robert H G Schwinger; Konrad Frank; Jochen Müller-Ehmsen; P Martin-Vasallo; T A Pressley; Anny H Xiang; E Erdmann; Alicia A McDonough
Regional expression of sodium pump subunits isoforms and Na+-Ca++ exchanger in the human heart.
The Journal of clinical investigation 1996;98(7):1650-8.
1996: Markus Flesch; Robert H G Schwinger; F Schiffer; Konrad Frank; Michael Südkamp; Ferdinand Kuhn-Regnier; G Arnold; Michael Böhm
Evidence for functional relevance of an enhanced expression of the Na(+)-Ca2+ exchanger in failing human myocardium.
Circulation 1996;94(5):992-1002.
1996: Robert H G Schwinger; C Schulz; Klara Brixius; Michael Böhm; Jochen Müller-Ehmsen; Erland Erdmann
Effect of epinine on tension of human renal arteries.
Naunyn-Schmiedeberg's archives of pharmacology 1996;354(3):343-7.
1996: Markus Flesch; Robert H G Schwinger; Petra Schnabel; F Schiffer; I van Gelder; U Bavendiek; Michael Südkamp; Ferdinand Kuhn-Regnier; Michael Böhm
Sarcoplasmic reticulum Ca2+ATPase and phospholamban mRNA and protein levels in end-stage heart failure due to ischemic or dilated cardiomyopathy.
Journal of molecular medicine (Berlin, Germany) 1996;74(6):321-32.
1996: Robert H G Schwinger; Jochen Müller-Ehmsen; Konrad Frank; A Koch; Erland Erdmann
Enhanced sensitivity of the failing human myocardium to cardiac glycosides and Na(+)-channel activators.
American heart journal 1996;131(5):988-93.
1996: Markus Flesch; F Pütz; Robert H G Schwinger; Michael Böhm
Functional relevance of an enhanced expression of the Na(+)-Ca2+ exchanger in the failing human heart.
Annals of the New York Academy of Sciences 1996;779():539-42.
1996: Robert H G Schwinger; Jochen Müller-Ehmsen; Michael Böhm; Erland Erdmann
Enantioselective inotropic actions of the Na+-channel activators BDF 9148, BDF 9196 and BDF 9167 in human failing and nonfailing myocardium.
The Journal of pharmacology and experimental therapeutics 1996;276(3):1180-8.
1996: Erland Erdmann; Robert H G Schwinger; D Beuckelmann; Michael Böhm
[Altered calcium homeostasis in chronic heart failure].
Zeitschrift für Kardiologie 1996;85 Suppl 6():123-28.
1996: U Bavendiek; Klara Brixius; Konrad Frank; Hannes Reuter; M Pietsch; A Gross; Jochen Müller-Ehmsen; Erland Erdmann; Robert H G Schwinger
Altered inotropism in the failing human myocardium.
Basic research in cardiology 1996;91 Suppl 2():9-16.
1995: Robert H G Schwinger; Michael Böhm; U Schmidt; P Karczewski; U Bavendiek; Markus Flesch; Ernst-Georg Krause; Erland Erdmann
Unchanged protein levels of SERCA II and phospholamban but reduced Ca2+ uptake and Ca(2+)-ATPase activity of cardiac sarcoplasmic reticulum from dilated cardiomyopathy patients compared with patients with nonfailing hearts.
Circulation 1995;92(11):3220-8.
1995: R Uhlmann; Robert H G Schwinger; I Lues; Erland Erdmann
EMD 53998 acts as Ca(2+)-sensitizer and phosphodiesterase III-inhibitor in human myocardium.
Basic research in cardiology 1995;90(5):365-71.
1995: Heiko Kilter; O Lenz; Karl La Rosée; Markus Flesch; Robert H G Schwinger; M Mädge; Ferdinand Kuhn-Regnier; Michael Böhm
Evidence against a role of nitric oxide in the indirect negative inotropic-effect of M-cholinoceptor stimulation in human ventricular myocardium.
Naunyn-Schmiedeberg's archives of pharmacology 1995;352(3):308-12.
1995: U Schmidt; Robert H G Schwinger; Michael Böhm
Interaction of halothane with inhibitory G-proteins in the human myocardium.
Anesthesiology 1995;83(2):353-60.
1995: U Schmidt; Robert H G Schwinger; Michael Böhm
Halothane restores the altered force-frequency relationship in failing human myocardium.
Anesthesiology 1995;82(6):1456-62.
1995: H Tawfik-Schlieper; M Moll; B Schmid; Robert H G Schwinger; Martin Paul; D Ganten; Michael Böhm
Alterations of cardiac alpha- and beta-adrenoceptors and inotropic responsiveness in hypertensive transgenic rats harbouring the mouse renin gene (TGR(mREN2)27).
Clinical and experimental hypertension (New York, N.Y. : 1993) 1995;17(4):631-48.
1995: Michael Böhm; Karl La Rosée; Robert H G Schwinger; Erland Erdmann
Evidence for reduction of norepinephrine uptake sites in the failing human heart.
Journal of the American College of Cardiology 1995;25(1):146-53.
1995: Erland Erdmann; Robert H G Schwinger; Michael Böhm
[Clinico-pharmacologic aspects of cardioactive drugs].
Klinische Anästhesiologie und Intensivtherapie 1995;47():46-60.
1994: U Schmidt; Robert H G Schwinger; Michael Böhm; Erland Erdmann
Alterations of the force-frequency relation depending on stages of heart failure in humans.
The American journal of cardiology 1994;74(10):1066-8.
1994: U Schmidt; Robert H G Schwinger; Jochen Müller-Ehmsen; S Böhm; L von Meyer; P Uberfuhr; B Reichart; Erland Erdmann; Michael Böhm
Influence of halothane on the effect of cAMP-dependent and cAMP-independent positive inotropic agents in human myocardium.
British journal of anaesthesia 1994;73(2):204-8.
1994: Michael Böhm; P Gierschik; Robert H G Schwinger; R Uhlmann; Erland Erdmann
Coupling of M-cholinoceptors and A1 adenosine receptors in human myocardium.
The American journal of physiology 1994;266(5 Pt 2):H1951-8.
1994: Robert H G Schwinger; Michael Böhm; A Koch; I Morano; J C Rüegg; Erland Erdmann
Inotropic effect of the cardioprotective agent 2,3-butanedione monoxime in failing and nonfailing human myocardium.
The Journal of pharmacology and experimental therapeutics 1994;269(2):778-86.
1994: Robert H G Schwinger; Michael Böhm; A Koch; U Schmidt; I Morano; H J Eissner; P Uberfuhr; B Reichart; Erland Erdmann
The failing human heart is unable to use the Frank-Starling mechanism.
Circulation research 1994;74(5):959-69.
1994: Michael Böhm; C Weinhold; Robert H G Schwinger; Jochen Müller-Ehmsen; D Böhm; H Reichenspurner; B Reichart; Erland Erdmann
Studies of the nucleoside transporter inhibitor, draflazine, in the human myocardium.
British journal of pharmacology 1994;112(1):137-42.
1994: Michael Böhm; U Schmidt; P Gierschik; Robert H G Schwinger; S Böhm; Erland Erdmann
Sensitization of adenylate cyclase by halothane in human myocardium and S49 lymphoma wild-type and cyc- cells: evidence for inactivation of the inhibitory G protein Gi alpha.
Molecular pharmacology 1994;45(3):380-9.
1993: Robert H G Schwinger; Michael Böhm; Jochen Müller-Ehmsen; R Uhlmann; U Schmidt; A Stäblein; P Uberfuhr; E Kreuzer; B Reichart; H J Eissner
Effect of inotropic stimulation on the negative force-frequency relationship in the failing human heart.
Circulation 1993;88(5 Pt 1):2267-76.
1993: U Schmidt; Robert H G Schwinger; S Böhm; P Uberfuhr; E Kreuzer; B Reichart; L Meyer; Erland Erdmann; Michael Böhm
Evidence for an interaction of halothane with the L-type Ca2+ channel in human myocardium.
Anesthesiology 1993;79(2):332-9.
1992: Robert H G Schwinger; Michael Böhm; R Uhlmann; Karl La Rosée; A Koch; Erland Erdmann
Increase of the extracellular magnesium concentration reduces cardiac glycoside toxicity in the human myocardium.
The Journal of pharmacology and experimental therapeutics 1992;263(3):1352-9.
1992: Michael Böhm; C Schulz; Robert H G Schwinger; Erland Erdmann
Positive inotropic effects due to partial agonistic activity of the beta-adrenoceptor antagonist celiprolol following amplification of cAMP formation in failing human myocardium.
Journal of cardiovascular pharmacology 1992;20(3):479-89.
1992: Robert H G Schwinger; Michael Böhm; Karl La Rosée; Erland Erdmann
Existence of PAF receptors in human platelets and human lung tissue but not in the human myocardium.
American heart journal 1992;124(2):320-30.
1992: Robert H G Schwinger; Michael Böhm; Karl La Rosée; U Schmidt; Erland Erdmann
Effect of the phosphodiesterase inhibitor UK 61260 on human myocardial inotropy and diastolic relaxation.
Journal of cardiovascular pharmacology 1992;19(6):966-74.
1992: Michael Böhm; Karl La Rosée; U Schmidt; C Schulz; Robert H G Schwinger; Erland Erdmann
Force-frequency relationship and inotropic stimulation in the nonfailing and failing human myocardium: implications for the medical treatment of heart failure.
The Clinical investigator 1992;70(5):421-5.
1992: Robert H G Schwinger; Erland Erdmann
Heart failure and electrolyte disturbances.
Methods and findings in experimental and clinical pharmacology 1992;14(4):315-25.
1992: Robert H G Schwinger; Michael Böhm; Karl La Rosée; U Schmidt; C Schulz; Erland Erdmann
Na(+)-channel activators increase cardiac glycoside sensitivity in failing human myocardium.
Journal of cardiovascular pharmacology 1992;19(4):554-61.
1992: Robert H G Schwinger; Michael Böhm; Erland Erdmann
Inotropic and lusitropic dysfunction in myocardium from patients with dilated cardiomyopathy.
American heart journal 1992;123(1):116-28.
1991: Robert H G Schwinger; Michael Böhm; C Mittmann; Karl La Rosée; Erland Erdmann
Evidence for a sustained effectiveness of sodium-channel activators in failing human myocardium.
Journal of molecular and cellular cardiology 1991;23(4):461-71.
1990: Michael Böhm; C Mittmann; Robert H G Schwinger; Erland Erdmann
Effects of xamoterol on inotropic and lusitropic properties of the human myocardium and on adenylate cyclase activity.
American heart journal 1990;120(6 Pt 1):1381-92.
1990: Michael Böhm; Robert H G Schwinger; Erland Erdmann
[Alterations of the cAMP-adenylate cyclase system in the failing human heart. Consequences for the therapy with inotropic drugs].
Klinische Wochenschrift 1990;68(18):887-95.
1990: Robert H G Schwinger; Michael Böhm; Erland Erdmann
Different negative inotropic activity of Ca2(+)-antagonists in human myocardial tissue.
Klinische Wochenschrift 1990;68(16):797-805.
1990: Robert H G Schwinger; Michael Böhm; Erland Erdmann
Effectiveness of cardiac glycosides in human myocardium with and without "downregulated" beta-adrenoceptors.
Journal of cardiovascular pharmacology 1990;15(5):692-7.
1990: Robert H G Schwinger; Michael Böhm; Erland Erdmann
The effect of xamoterol in failing human myocardium.
European heart journal 1990;11(4):323-7.
1989: Michael Böhm; Burkert Pieske; P Schnabel; Robert H G Schwinger; B Kemkes; W P Klövekorn; Erland Erdmann
Reduced effects of dopexamine on force of contraction in the failing human heart despite preserved beta 2-adrenoceptor subpopulation.
Journal of cardiovascular pharmacology 1989;14(4):549-59.