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Debra Schwinn

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Anush Oganesian; William C Parks; Vladimir Yarov-Yarovoy; Debra A Schwinn
Constitutive coupling of a naturally occurring human alpha1a-adrenergic receptor genetic variant to EGFR transactivation pathway.
Peter von Homeyer; Debra A Schwinn
Pharmacogenomics of β-adrenergic receptor physiology and response to β-blockade.
Ian J Welsby; Mihai V Podgoreanu; Barbara Phillips-Bute; Richard Morris; Joseph P Mathew; Peter K Smith; Mark F Newman; Debra A Schwinn; Mark Stafford-Smith
Association of the 98T ELAM-1 polymorphism with increased bleeding after cardiac surgery.

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2011: Anush Oganesian; William C Parks; Vladimir Yarov-Yarovoy; Debra A Schwinn
Constitutive coupling of a naturally occurring human alpha1a-adrenergic receptor genetic variant to EGFR transactivation pathway.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(49):19796-801.
2011: Peter von Homeyer; Debra A Schwinn
Pharmacogenomics of β-adrenergic receptor physiology and response to β-blockade.
Anesthesia and analgesia 2011;113(6):1305-18.
2010: Ian J Welsby; Mihai V Podgoreanu; Barbara Phillips-Bute; Richard Morris; Joseph P Mathew; Peter K Smith; Mark F Newman; Debra A Schwinn; Mark Stafford-Smith
Association of the 98T ELAM-1 polymorphism with increased bleeding after cardiac surgery.
Journal of cardiothoracic and vascular anesthesia 2010;24(3):427-33.
2009: Beilei Lei; Daniel P Morris; Michael P Smith; Debra A Schwinn
Lipid rafts constrain basal alpha(1A)-adrenergic receptor signaling by maintaining receptor in an inactive conformation.
Cellular signalling 2009;21(10):1532-9.
2008: Jerry H Kim; Debra A Schwinn; Ruth Landau
Pharmacogenomics and perioperative medicine--implications for modern clinical practice.
Canadian journal of anaesthesia = Journal canadien d'anesthésie 2008;55(12):799-806.
2008: Barbara Phillips-Bute; Joseph P Mathew; James A Blumenthal; Richard Morris; Mihai V Podgoreanu; Michael Smith; Mark Stafford-Smith; Hilary P Grocott; Debra A Schwinn; Mark F Newman
Relationship of genetic variability and depressive symptoms to adverse events after coronary artery bypass graft surgery.
Psychosomatic medicine 2008;70(9):953-9.
2008: Aslan T Turer; Debra A Schwinn
Understanding the transition to acute illness: the promise of perioperative genomics.
Journal of cardiovascular translational research 2008;1(2):171-3.
2008: Debra A Schwinn; Mihai Podgoreanu
Pharmacogenomics and end-organ susceptibility to injury in the perioperative period.
Best practice & research. Clinical anaesthesiology 2008;22(1):23-37.
2008: Daniel P Morris; Beilei Lei; Yue-Xuan Wu; Gregory A Michelotti; Debra A Schwinn
The alpha1a-adrenergic receptor occupies membrane rafts with its G protein effectors but internalizes via clathrin-coated pits.
The Journal of biological chemistry 2008;283(5):2973-85.
2007: Mark Stafford-Smith; Raquel Bartz; Katrina Wilson; James N Baraniuk; Debra A Schwinn
Alpha-adrenergic mRNA subtype expression in the human nasal turbinate.
Canadian journal of anaesthesia = Journal canadien d'anesthésie 2007;54(7):549-55.
2007: Gregory A Michelotti; D Marshall Brinkley; Daniel P Morris; Michael P Smith; Raphael J Louie; Debra A Schwinn
Epigenetic regulation of human alpha1d-adrenergic receptor gene expression: a role for DNA methylation in Sp1-dependent regulation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(9):1979-93.
2007: Joseph P Mathew; Mihai V Podgoreanu; Hilary P Grocott; William D White; Richard Morris; Mark Stafford-Smith; G Burkhard Mackensen; Christine S Rinder; James A Blumenthal; Debra A Schwinn; Mark F Newman
Genetic variants in P-selectin and C-reactive protein influence susceptibility to cognitive decline after cardiac surgery.
Journal of the American College of Cardiology 2007;49(19):1934-42.
2006: Debra A Schwinn; Natalie A Afshari
alpha(1)-Adrenergic receptor antagonists and the iris: new mechanistic insights into floppy iris syndrome.
Survey of ophthalmology 2006;51(5):501-12.
2006: Mihai V Podgoreanu; William D White; Richard Morris; Joseph P Mathew; Mark Stafford-Smith; Ian J Welsby; Hilary P Grocott; Carmelo A Milano; Mark F Newman; Debra A Schwinn
Inflammatory gene polymorphisms and risk of postoperative myocardial infarction after cardiac surgery.
Circulation 2006;114(1 Suppl):I275-81.
2006: Debra A Schwinn; Jeffrey R Balser
Anesthesiology physician scientists in academic medicine: a wake-up call.
Anesthesiology 2006;104(1):170-8.
2005: Mihai V Podgoreanu; Debra A Schwinn
New paradigms in cardiovascular medicine: emerging technologies and practices: perioperative genomics.
Journal of the American College of Cardiology 2005;46(11):1965-77.
2005: Debra A Schwinn; Natalie A Afshari
Alpha1-adrenergic antagonists and floppy iris syndrome: tip of the iceberg?
Ophthalmology 2005;112(12):2059-60.
2005: Eugene W Moretti; Richard Morris; Mihai V Podgoreanu; Debra A Schwinn; Mark F Newman; Ellen Bennett; Victor G Moulin; Uzo U Mba; Daniel T Laskowitz
APOE polymorphism is associated with risk of severe sepsis in surgical patients.
Critical care medicine 2005;33(11):2521-6.
2005: Daniel P Morris; Gregory A Michelotti; Debra A Schwinn
Evidence that phosphorylation of the RNA polymerase II carboxyl-terminal repeats is similar in yeast and humans.
The Journal of biological chemistry 2005;280(36):31368-77.
2005: Hilary P Grocott; William D White; Richard Morris; Mihai V Podgoreanu; Joseph P Mathew; Dahlia M Nielsen; Debra A Schwinn; Mark F Newman
Genetic polymorphisms and the risk of stroke after cardiac surgery.
Stroke; a journal of cerebral circulation 2005;36(9):1854-8.
2005: Mihai V Podgoreanu; Gregory A Michelotti; Yukie Sato; Michael P Smith; Simon Lin; Richard Morris; Hilary P Grocott; Joseph P Mathew; Debra A Schwinn
Differential cardiac gene expression during cardiopulmonary bypass: ischemia-independent upregulation of proinflammatory genes.
The Journal of thoracic and cardiovascular surgery 2005;130(2):330-9.
2005: Debra A Schwinn; Mihai V Podgoreanu
The new age of medical genomics.
British journal of anaesthesia 2005;95(2):119-21.
2005: Ian J Welsby; Mihai V Podgoreanu; Barbara Phillips-Bute; Joseph P Mathew; Peter K Smith; Mark F Newman; Debra A Schwinn; Mark Stafford-Smith
Genetic factors contribute to bleeding after cardiac surgery.
Journal of thrombosis and haemostasis : JTH 2005;3(6):1206-12.
2005: Beilei Lei; Daniel P Morris; Michael P Smith; Laura P Svetkey; Mark F Newman; Jerome I Rotter; Thomas A Buchanan; Stephen Beckstrom-Sternberg; Eric Green; Debra A Schwinn
Novel human alpha1a-adrenoceptor single nucleotide polymorphisms alter receptor pharmacology and biological function.
Naunyn-Schmiedeberg's archives of pharmacology 2005;371(3):229-39.
2005: Mark Stafford-Smith; Mihai V Podgoreanu; Madhav Swaminathan; Barbara Phillips-Bute; Joseph P Mathew; Elizabeth H Hauser; Michelle P Winn; Carmelo A Milano; Dahlia M Nielsen; Mike Smith; Richard Morris; Mark F Newman; Debra A Schwinn
Association of genetic polymorphisms with risk of renal injury after coronary bypass graft surgery.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2005;45(3):519-30.
2005: UB Schambra; G Burkhard Mackensen; Mark Stafford-Smith; D E Haines; Debra A Schwinn
Neuron specific alpha-adrenergic receptor expression in human cerebellum: implications for emerging cerebellar roles in neurologic disease.
Neuroscience 2005;135(2):507-23.
2004: Debra A Schwinn; David T Price; Perinchery Narayan
alpha1-Adrenoceptor subtype selectivity and lower urinary tract symptoms.
Mayo Clinic proceedings. Mayo Clinic 2004;79(11):1423-34.
2004: Daniel P Morris; R Reyn Price; Michael P Smith; Beilei Lei; Debra A Schwinn
Cellular trafficking of human alpha1a-adrenergic receptors is continuous and primarily agonist-independent.
Molecular pharmacology 2004;66(4):843-54.
2004: K Ashley Hawrylyshyn; Gregory A Michelotti; Francis Cogé; Sophie-Pénélope Guénin; Debra A Schwinn
Update on human alpha1-adrenoceptor subtype signaling and genomic organization.
Trends in pharmacological sciences 2004;25(9):449-55.
2004: Gregory A Michelotti; Debra A Schwinn
Mechanistic insights into the role of alpha1adrenergic receptors in lower urinary tract symptoms.
Current urology reports 2004;5(4):258-66.
2004: Baojun Gu; Jerome P Reiter; Debra A Schwinn; Michael P Smith; Cees Korstanje; Karl B Thor; Paul C Dolber
Effects of alpha 1-adrenergic receptor subtype selective antagonists on lower urinary tract function in rats with bladder outlet obstruction.
The Journal of urology 2004;172(2):758-62.
2004: Mihai V Podgoreanu; Debra A Schwinn
Genomics and the circulation.
British journal of anaesthesia 2004;93(1):140-8.
2004: John V Booth; Erin E Ward; Kelly C Colgan; Bonita L Funk; Habib El-Moalem; Michael P Smith; Carmelo A Milano; Peter K Smith; Mark F Newman; Debra A Schwinn
Metoprolol and coronary artery bypass grafting surgery: does intraoperative metoprolol attenuate acute beta-adrenergic receptor desensitization during cardiac surgery?
Anesthesia and analgesia 2004;98(5):1224-31, table of contents.
2003: Gregory A Michelotti; Monica J Bauman; Michael P Smith; Debra A Schwinn
Cloning and characterization of the rat alpha 1a-adrenergic receptor gene promoter. Demonstration of cell specificity and regulation by hypoxia.
The Journal of biological chemistry 2003;278(10):8693-705.
2003: Scott A Hagen; Amy L Kondyra; Hilary P Grocott; Habib El-Moalem; Daniel Bainbridge; Joseph P Mathew; Mark F Newman; Joseph Gerald Reves; Debra A Schwinn; Madan M Kwatra
Cardiopulmonary bypass decreases G protein-coupled receptor kinase activity and expression in human peripheral blood mononuclear cells.
Anesthesiology 2003;98(2):343-8.
2002: John V Booth; Donat R Spahn; Robert L McRae; Lynn C Chesnut; Habib El-Moalem; Darryl M Atwell; Bruce J Leone; Debra A Schwinn
Esmolol improves left ventricular function via enhanced beta-adrenergic receptor signaling in a canine model of coronary revascularization.
Anesthesiology 2002;97(1):162-9.
2002: David W Amory; Alina Grigore; John K Amory; Mark A Gerhardt; William D White; Peter K Smith; Debra A Schwinn; Joseph Gerald Reves; Mark F Newman
Neuroprotection is associated with beta-adrenergic receptor antagonists during cardiac surgery: evidence from 2,575 patients.
Journal of cardiothoracic and vascular anesthesia 2002;16(3):270-7.
2002: R Reyn Price; Daniel P Morris; Gopa Biswas; Michael P Smith; Debra A Schwinn
Acute agonist-mediated desensitization of the human alpha 1a-adrenergic receptor is primarily independent of carboxyl terminus regulation: implications for regulation of alpha 1aAR splice variants.
The Journal of biological chemistry 2002;277(11):9570-9.
2002: Christian Hampel; Paul C Dolber; Michael P Smith; Sandra L Savic; Joachim W Th roff; Karl B Thor; Debra A Schwinn
Modulation of bladder alpha1-adrenergic receptor subtype expression by bladder outlet obstruction.
The Journal of urology 2002;167(3):1513-21.
2002: Debra A Schwinn; John V Booth
Genetics infuses new life into human physiology: implications of the human genome project for anesthesiology and perioperative medicine.
Anesthesiology 2002;96(2):261-3.
2001: Debra A Schwinn
The role of alpha1-adrenergic receptor subtypes in lower urinary tract symptoms.
BJU international 2001;88 Suppl 2():27-34; discussion 49-50.
2000: Gregory A Michelotti; David T Price; Debra A Schwinn
Alpha 1-adrenergic receptor regulation: basic science and clinical implications.
Pharmacology & therapeutics 2000;88(3):281-309.
2000: David T Price; XL Rudner; Gregory A Michelotti; Debra A Schwinn
Immortalization of a human prostate stromal cell line using a recombinant retroviral approach.
The Journal of urology 2000;164(6):2145-50.
2000: Jason D Kilts; Mark A Gerhardt; Mark D Richardson; Gautam M Sreeram; G Burkhard Mackensen; Hilary P Grocott; William D White; R D Davis; Mark F Newman; Joseph Gerald Reves; Debra A Schwinn; Madan M Kwatra
Beta(2)-adrenergic and several other G protein-coupled receptors in human atrial membranes activate both G(s) and G(i).
Circulation research 2000;87(8):705-9.
2000: Debra A Schwinn
Novel role for alpha1-adrenergic receptor subtypes in lower urinary tract symptoms.
BJU international 2000;86 Suppl 2():11-20; discussion 20-2.
2000: Robert E Shapiro; Bradford D Winters; M Hales; T Barnett; Debra A Schwinn; Nicholas Flavahan; Dan E Berkowitz
Endogenous circulating sympatholytic factor in orthostatic intolerance.
Hypertension 2000;36(4):553-60.
2000: Debra A Schwinn; Gregory A Michelotti
alpha1-adrenergic receptors in the lower urinary tract and vascular bed: potential role for the alpha1d subtype in filling symptoms and effects of ageing on vascular expression.
BJU international 2000;85 Suppl 2():6-11.
2000: R R Ongioco; CD Richardson; XL Rudner; Mark Stafford-Smith; Debra A Schwinn
Alpha2-adrenergic receptors in human dorsal root ganglia: predominance of alpha2b and alpha2c subtype mRNAs.
Anesthesiology 2000;92(4):968-76.
2000: M S Smith; Debra A Schwinn
In situ hybridization of adrenergic receptor mRNA in brain.
Methods in molecular biology (Clifton, N.J.) 2000;126():519-33.
1999: XL Rudner; Dan E Berkowitz; John V Booth; Bonita L Funk; K L Cozart; E B D'Amico; Habib El-Moalem; SO Page; CD Richardson; Bradford D Winters; L Marucci; Debra A Schwinn
Subtype specific regulation of human vascular alpha(1)-adrenergic receptors by vessel bed and age.
Circulation 1999;100(23):2336-43.
1999: Mark Goepel; Susanne Krege; David T Price; Gregory A Michelotti; Debra A Schwinn; MC Michel
Characterization of alpha-adrenoceptor subtypes in the corpus cavernosum of patients undergoing sex change surgery.
The Journal of urology 1999;162(5):1793-9.
1999: David T Price; G Della Rocca; Chuanhai Guo; M S Ballo; Debra A Schwinn; Louis M Luttrell
Activation of extracellular signal-regulated kinase in human prostate cancer.
The Journal of urology 1999;162(4):1537-42.
1999: M S Smith; UB Schambra; Kenneth H Wilson; SO Page; Debra A Schwinn
Alpha1-adrenergic receptors in human spinal cord: specific localized expression of mRNA encoding alpha1-adrenergic receptor subtypes at four distinct levels.
Brain research. Molecular brain research 1999;63(2):254-61.
1999: Debra A Schwinn; R Reyn Price
Molecular pharmacology of human alpha1-adrenergic receptors: unique features of the alpha 1a-subtype.
European urology 1999;36 Suppl 1():7-10.
1998: Mark A Gerhardt; John V Booth; Lynn C Chesnut; Bonita L Funk; Habib El-Moalem; Madan M Kwatra; Debra A Schwinn
Acute myocardial beta-adrenergic receptor dysfunction after cardiopulmonary bypass in patients with cardiac valve disease. Duke Heart Center Perioperative Desensitization Group.
Circulation 1998;98(19 Suppl):II275-81.
1998: John V Booth; Kevin Paul Landolfo; Lynn C Chesnut; Elliott Bennett-Guerrero; Mark A Gerhardt; Darryl M Atwell; Habib El-Moalem; MS Smith; Bonita L Funk; Cynthia M Kuhn; Madan M Kwatra; Debra A Schwinn
Acute depression of myocardial beta-adrenergic receptor signaling during cardiopulmonary bypass: impairment of the adenylyl cyclase moiety. Duke Heart Center Perioperative Desensitization Group.
Anesthesiology 1998;89(3):602-11.
1998: B J Malloy; David T Price; R Reyn Price; A M Bienstock; M K Dole; Bonita L Funk; XL Rudner; CD Richardson; Craig F Donatucci; Debra A Schwinn
Alpha1-adrenergic receptor subtypes in human detrusor.
The Journal of urology 1998;160(3 Pt 1):937-43.
1998: Debra A Schwinn; E R DeLong; Steven Shafer
Writing successful research proposals for medical science.
Anesthesiology 1998;88(6):1660-6.
1998: D R Scanga; Debra A Schwinn
Transcriptional regulation of alpha-1 adrenergic receptors.
Frontiers in bioscience : a journal and virtual library 1998;3():d348-53.
1998: K Lee; CD Richardson; M A Razik; Madan M Kwatra; Debra A Schwinn
Multiple potential regulatory elements in the 5' flanking region of the human alpha 1a-adrenergic receptor.
DNA sequence : the journal of DNA sequencing and mapping 1998;8(4):271-6.
1998: Kinya Nishimura; Kengo Warabi; Eric D Roush; J Frederick; Debra A Schwinn; Madan M Kwatra
Characterization of GRK2-catalyzed phosphorylation of the human substance P receptor in Sf9 membranes.
Biochemistry 1998;37(5):1192-8.
1998: Richard M Smiley; Madan M Kwatra; Debra A Schwinn
New developments in cardiovascular adrenergic receptor pharmacology: molecular mechanisms and clinical relevance.
Journal of cardiothoracic and vascular anesthesia 1998;12(1):80-95.
1998: Debra A Schwinn; Madan M Kwatra
Expression and regulation of alpha 1-adrenergic receptors in human tissues.
Advances in pharmacology (San Diego, Calif.) 1998;42():390-4.
1997: M A Razik; K Lee; R Reyn Price; M R Williams; R R Ongjoco; M K Dole; XL Rudner; Madan M Kwatra; Debra A Schwinn
Transcriptional regulation of the human alpha1a-adrenergic receptor gene. Characterization Of the 5'-regulatory and promoter region.
The Journal of biological chemistry 1997;272(45):28237-46.
1997: CD Richardson; Craig F Donatucci; SO Page; Kenneth H Wilson; Debra A Schwinn
Pharmacology of tamsulosin: saturation-binding isotherms and competition analysis using cloned alpha 1-adrenergic receptor subtypes.
The Prostate 1997;33(1):55-9.
1997: Elliott Bennett-Guerrero; David C Kramer; Debra A Schwinn
Effect of chronic and acute thyroid hormone reduction on perioperative outcome.
Anesthesia and analgesia 1997;85(1):30-6.
1997: J P Tan; Frederic J Seidler; Debra A Schwinn; SO Page; Theodore A Slotkin
A critical period for the role of thyroid hormone in development of renal alpha-adrenergic receptors.
Pediatric research 1997;42(1):93-102.
1997: Kenneth H Wilson; UB Schambra; M S Smith; SO Page; CD Richardson; robert fremeau; Debra A Schwinn
In situ hybridization: identification of rare mRNAs in human tissues.
Brain research. Brain research protocols 1997;1(2):175-85.
1997: Paul M Kirshbom; SO Page; M Todd Jacobs; Steven S L Tsui; E Bello; Ross M Ungerleider; Debra A Schwinn; JW Gaynor
Cardiopulmonary bypass and circulatory arrest increase endothelin-1 production and receptor expression in the lung.
The Journal of thoracic and cardiovascular surgery 1997;113(4):777-83.
1996: E A Bello; Debra A Schwinn
Molecular biology and medicine. A primer for the clinician.
Anesthesiology 1996;85(6):1462-78.
1996: J P Lacey; Craig F Donatucci; David T Price; SO Page; Steffany A L Bennett; Martin Tenniswood; Debra A Schwinn
Effects of androgen deprivation on prostate alpha 1-adrenergic receptors.
Urology 1996;48(2):335-41.
1996: B Chen; R D Leverette; Debra A Schwinn; Madan M Kwatra
Human G(alpha q): cDNA and tissue distribution.
Biochimica et biophysica acta 1996;1281(2):125-8.
1996: Paul M Kirshbom; M Todd Jacobs; Steven S L Tsui; L R DiBernardo; Debra A Schwinn; Ross M Ungerleider; J William Gaynor
Effects of cardiopulmonary bypass and circulatory arrest on endothelium-dependent vasodilation in the lung.
The Journal of thoracic and cardiovascular surgery 1996;111(6):1248-56.
1996: Dan E Berkowitz; C Richardson; D A Elliott; J B Leslie; Debra A Schwinn
Hypotension resistant to therapy with alpha receptor agonists complicating cardiopulmonary bypass: lithium as a potential cause.
Anesthesia and analgesia 1996;82(5):1082-5.
1996: Elliott Bennett-Guerrero; J L Jimenez; William D White; E B D'Amico; B I Baldwin; Debra A Schwinn
Cardiovascular effects of intravenous triiodothyronine in patients undergoing coronary artery bypass graft surgery. A randomized, double-blind, placebo- controlled trial. Duke T3 study group.
JAMA : the journal of the American Medical Association 1996;275(9):687-92.
1995: M S Smith; U B Schambra; Kenneth H Wilson; SO Page; C Hulette; Alan R Light; Debra A Schwinn
alpha 2-Adrenergic receptors in human spinal cord: specific localized expression of mRNA encoding alpha 2-adrenergic receptor subtypes at four distinct levels.
Brain research. Molecular brain research 1995;34(1):109-17.
1995: Madan M Kwatra; J Schreurs; Debra A Schwinn; M A Innis; Marc G Caron; R J Lefkowitz
Immunoaffinity purification of epitope-tagged human beta 2-adrenergic receptor to homogeneity.
Protein expression and purification 1995;6(6):717-21.
1995: Thomas A D'Amico; C H Meyers; TC Koutlas; D S Peterseim; D C Sabiston; P Van Trigt; Debra A Schwinn
Desensitization of myocardial beta-adrenergic receptors and deterioration of left ventricular function after brain death.
The Journal of thoracic and cardiovascular surgery 1995;110(3):746-51.
1995: Paul M Kirshbom; Steven S L Tsui; L R DiBernardo; Jon Meliones; Debra A Schwinn; Ross M Ungerleider; J William Gaynor
Blockade of endothelin-converting enzyme reduces pulmonary hypertension after cardiopulmonary bypass and circulatory arrest.
Surgery 1995;118(2):440-4; discussion 444-5.
1995: Dan E Berkowitz; N A Nardone; Richard M Smiley; David T Price; D K Kreutter; robert fremeau; Debra A Schwinn
Distribution of beta 3-adrenoceptor mRNA in human tissues.
European journal of pharmacology 1995;289(2):223-8.
1995: JO Margolis; B J McGrath; Peter S Kussin; Debra A Schwinn
Do not resuscitate (DNR) orders during surgery: ethical foundations for institutional policies in the United States.
Anesthesia and analgesia 1995;80(4):806-9.
1995: Debra A Schwinn; G I Johnston; SO Page; M J Mosley; Kenneth H Wilson; N P Worman; S Campbell; M D Fidock; L M Furness; D J Parry-Smith
Cloning and pharmacological characterization of human alpha-1 adrenergic receptors: sequence corrections and direct comparison with other species homologues.
The Journal of pharmacology and experimental therapeutics 1995;272(1):134-42.
1994: Dan E Berkowitz; David T Price; E A Bello; SO Page; Debra A Schwinn
Localization of messenger RNA for three distinct alpha 2-adrenergic receptor subtypes in human tissues. Evidence for species heterogeneity and implications for human pharmacology.
Anesthesiology 1994;81(5):1235-44.
1994: David T Price; Ravi Chari; Dan E Berkowitz; William C Meyers; Debra A Schwinn
Expression of alpha 1-adrenergic receptor subtype mRNA in rat tissues and human SK-N-MC neuronal cells: implications for alpha 1-adrenergic receptor subtype classification.
Molecular pharmacology 1994;46(2):221-6.
1994: D S Peterseim; L C Chesnut; C H Meyers; Thomas A D'Amico; P Van Trigt; Debra A Schwinn
Stability of the beta-adrenergic receptor/adenylyl cyclase pathway of pediatric myocardium after brain death.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 1994;13(4):635-40.
1994: David T Price; R J Lefkowitz; Marc G Caron; Dan E Berkowitz; Debra A Schwinn
Localization of mRNA for three distinct alpha 1-adrenergic receptor subtypes in human tissues: implications for human alpha-adrenergic physiology.
Molecular pharmacology 1994;45(2):171-5.
1994: Debra A Schwinn
Adrenergic receptors: unique localization in human tissues.
Advances in pharmacology (San Diego, Calif.) 1994;31():333-41.
1993: R J Franiak; Debra A Schwinn
Acute myelogenous leukemia: implications of acute blast crisis and cardiopulmonary bypass.
Journal of cardiothoracic and vascular anesthesia 1993;7(4):455-7.
1993: David T Price; Debra A Schwinn; J W Lomasney; L F Allen; Marc G Caron; R J Lefkowitz
Identification, quantification, and localization of mRNA for three distinct alpha 1 adrenergic receptor subtypes in human prostate.
The Journal of urology 1993;150(2 Pt 1):546-51.
1993: Debra A Schwinn
Adrenoceptors as models for G protein-coupled receptors: structure, function and regulation.
British journal of anaesthesia 1993;71(1):77-85.
1993: Madan M Kwatra; Debra A Schwinn; J Schreurs; J L Blank; C M Kim; J L Benovic; J E Krause; Marc G Caron; R J Lefkowitz
The substance P receptor, which couples to Gq/11, is a substrate of beta-adrenergic receptor kinase 1 and 2.
The Journal of biological chemistry 1993;268(13):9161-4.
1992: Debra A Schwinn; J W Lomasney
Pharmacologic characterization of cloned alpha 1-adrenoceptor subtypes: selective antagonists suggest the existence of a fourth subtype.
European journal of pharmacology 1992;227(4):433-6.
1992: C D Lu; Debra A Schwinn
Management of a difficult intubation during acute myocardial ischemia following a failed angioplasty.
Journal of cardiothoracic and vascular anesthesia 1992;6(3):335-7.
1992: R F Thomas; B D Holt; Debra A Schwinn; Stephen B Liggett
Long-term agonist exposure induces upregulation of beta 3-adrenergic receptor expression via multiple cAMP response elements.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(10):4490-4.
1991: Debra A Schwinn; C Correa-Sales; SO Page; Mervyn Maze
Functional effects of activation of alpha-1 adrenoceptors by dexmedetomidine: in vivo and in vitro studies.
The Journal of pharmacology and experimental therapeutics 1991;259(3):1147-52.
1991: Debra A Schwinn; Bruce J Leone; Donat R Spahn; L C Chesnut; SO Page; R L McRae; Stephen B Liggett
Desensitization of myocardial beta-adrenergic receptors during cardiopulmonary bypass. Evidence for early uncoupling and late downregulation.
Circulation 1991;84(6):2559-67.
1991: Debra A Schwinn; SO Page; J P Middleton; W Lorenz; Stephen B Liggett; K Yamamoto; E G Lapetina; Marc G Caron; R J Lefkowitz; S Cotecchia
The alpha 1C-adrenergic receptor: characterization of signal transduction pathways and mammalian tissue heterogeneity.
Molecular pharmacology 1991;40(5):619-26.
1991: J W Lomasney; S Cotecchia; W Lorenz; W Y Leung; Debra A Schwinn; T L Yang-Feng; M Brownstein; R J Lefkowitz; Marc G Caron
Molecular cloning and expression of the cDNA for the alpha 1A-adrenergic receptor. The gene for which is located on human chromosome 5.
The Journal of biological chemistry 1991;266(10):6365-9.
1991: Stephen B Liggett; Debra A Schwinn
Multiple potential regulatory elements in the 5' flanking region of the beta 3-adrenergic receptor.
DNA sequence : the journal of DNA sequencing and mapping 1991;2(1):61-3.
1990: Debra A Schwinn; R W McIntyre; Joseph Gerald Reves
Isoflurane-induced vasodilation: role of the alpha-adrenergic nervous system.
Anesthesia and analgesia 1990;71(5):451-9.
1990: Debra A Schwinn; J W Lomasney; W Lorenz; P J Szklut; robert fremeau; T L Yang-Feng; Marc G Caron; R J Lefkowitz; S Cotecchia
Molecular cloning and expression of the cDNA for a novel alpha 1-adrenergic receptor subtype.
The Journal of biological chemistry 1990;265(14):8183-9.
1990: Debra A Schwinn; S Cotecchia; W Lorenz; Marc G Caron; R J Lefkowitz
The alpha 1C-adrenergic receptor: a new member in the alpha 1-adrenergic receptor family.
Transactions of the Association of American Physicians 1990;103():112-8.
1989: Debra A Schwinn; Joseph Gerald Reves
Time course and hemodynamic effects of alpha-1-adrenergic bolus administration in anesthetized patients with myocardial disease.
Anesthesia and analgesia 1989;68(5):571-8.
1989: R W McIntyre; Debra A Schwinn
Atrial natriuretic peptide.
Journal of cardiothoracic anesthesia 1989;3(1):91-8.
1988: S Cotecchia; Debra A Schwinn; Richard R Randall; R J Lefkowitz; Marc G Caron; B K Kobilka
Molecular cloning and expression of the cDNA for the hamster alpha 1-adrenergic receptor.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(19):7159-63.
1988: Debra A Schwinn; R W McIntyre; E D Hawkins; R A Kates; Joseph Gerald Reves
alpha 1-Adrenergic responsiveness during coronary artery bypass surgery: effect of preoperative ejection fraction.
Anesthesiology 1988;69(2):206-17.