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Marco Scocchi

Research Profile

Chemicals & Drugs

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Genes & Molecular Sequences

Amino Acid Sequences

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Microbial Sensitivity Tests

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Publications

TOP 3
Victoria S Paulsen; Marco Scocchi; Olaf B Styrvold; Monica Benincasa; Hans-Matti Blencke; Jacobus J Eksteen; Tor Haug; Klara Stensvåg
Structure-activity relationships of the antimicrobial peptide arasin 1 - and mode of action studies of the N-terminal, proline-rich region.
M F F Arnold; C E Barry; H I Boshoff; D J Campopiano; S Capewell; Andreas F Haag; E K James; B Kerscher; I Mair; R McDonald; Peter Mergaert; A M Mitchell; T J Mitchell; Marco Scocchi; Matteo Zanda; GP Ferguson
Partial complementation of Sinorhizobium meliloti bacA mutant phenotypes by the Mycobacterium tuberculosis BacA protein.
Arianna Pompilio; Stefano Pomponio; Marco Scocchi; Valentina Crocetta; Valentina Di Vincenzo; Giordano Dicuonzo; Ersilia Fiscarelli; Renato Gennaro; Giovanni Gherardi; Mario Mardirossian; Giovanni Di Bonaventura
Potential novel therapeutic strategies in cystic fibrosis: antimicrobial and anti-biofilm activity of natural and designed α-helical peptides against Staphylococcus aureus, Pseudomonas aeruginosa, and Stenotrophomonas maltophilia.

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All Publications

2013: Victoria S Paulsen; Marco Scocchi; Olaf B Styrvold; Monica Benincasa; Hans-Matti Blencke; Jacobus J Eksteen; Tor Haug; Klara Stensvåg
Structure-activity relationships of the antimicrobial peptide arasin 1 - and mode of action studies of the N-terminal, proline-rich region.
PloS one 2013;8(1):e53326.
2013: M F F Arnold; C E Barry; H I Boshoff; D J Campopiano; S Capewell; Andreas F Haag; E K James; B Kerscher; I Mair; R McDonald; Peter Mergaert; A M Mitchell; T J Mitchell; Marco Scocchi; Matteo Zanda; GP Ferguson
Partial complementation of Sinorhizobium meliloti bacA mutant phenotypes by the Mycobacterium tuberculosis BacA protein.
Journal of bacteriology 2013;195(2):389-98.
2012: Arianna Pompilio; Stefano Pomponio; Marco Scocchi; Valentina Crocetta; Valentina Di Vincenzo; Giordano Dicuonzo; Ersilia Fiscarelli; Renato Gennaro; Giovanni Gherardi; Mario Mardirossian; Giovanni Di Bonaventura
Potential novel therapeutic strategies in cystic fibrosis: antimicrobial and anti-biofilm activity of natural and designed α-helical peptides against Staphylococcus aureus, Pseudomonas aeruginosa, and Stenotrophomonas maltophilia.
BMC microbiology 2012;12():145.
2012: Alessandro Tossi; Sotir Zahariev; Marco Scocchi; Renato Gennaro
Use of unnatural amino acids to probe structure-activity relationships and mode-of-action of antimicrobial peptides.
Methods in molecular biology (Clifton, N.J.) 2012;794():169-83.
2011: Marco Scocchi; Alessandro Tossi; Renato Gennaro
Proline-rich antimicrobial peptides: converging to a non-lytic mechanism of action.
Cellular and molecular life sciences : CMLS 2011;68(13):2317-30.
2010: Silvia Wehmeier; Markus F F Arnold; Victoria L Marlow; Mustapha Aouida; Kamila K Myka; Vivien Fletcher; Monica Benincasa; Marco Scocchi; Dindial Ramotar; GP Ferguson
Internalization of a thiazole-modified peptide in Sinorhizobium meliloti occurs by BacA-dependent and -independent mechanisms.
Microbiology (Reading, England) 2010;156(Pt 9):2702-13.
2010: Roberto Aquilani; Marco Scocchi; Paolo Iadarola; Simona Viglio; evasio pasini; Salvatore Condello; Federica Boschi; Ornella Pastoris; Andria I Bongiorno; Manuela Verri
Spontaneous neurocognitive retrieval of patients with sub-acute ischemic stroke is associated with dietary protein intake.
Nutritional neuroscience 2010;13(3):129-34.
2010: Ramakrishnan Karunakaran; Andreas F Haag; Alison K East; Vinoy Ramachandran; Juergen Prell; Euan K James; Marco Scocchi; GP Ferguson; Philip Poole
BacA is essential for bacteroid development in nodules of galegoid, but not phaseoloid, legumes.
Journal of bacteriology 2010;192(11):2920-8.
2010: Monica Benincasa; Chiara Pelillo; Sonia Zorzet; Chiara Garrovo; Stefania Biffi; Renato Gennaro; Marco Scocchi
The proline-rich peptide Bac7(1-35) reduces mortality from Salmonella typhimurium in a mouse model of infection.
BMC microbiology 2010;10():178.
2009: Roberto Aquilani; Paola Baiardi; Marco Scocchi; Paolo Iadarola; Manuela Verri; Paolo Sessarego; Federica Boschi; evasio pasini; Ornella Pastoris; Simona Viglio
Normalization of zinc intake enhances neurological retrieval of patients suffering from ischemic strokes.
Nutritional neuroscience 2009;12(5):219-25.
2009: Monica Benincasa; Sabrina Pacor; Renato Gennaro; Marco Scocchi
Rapid and reliable detection of antimicrobial peptide penetration into gram-negative bacteria based on fluorescence quenching.
Antimicrobial agents and chemotherapy 2009;53(8):3501-4.
2009: Marco Scocchi; Alberto Pallavicini; Roberto Salgaro; Karol Bociek; Renato Gennaro
The salmonid cathelicidins: a gene family with highly varied C-terminal antimicrobial domains.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2009;152(4):376-81.
2009: Victoria L Marlow; Andreas F Haag; Hajime Kobayashi; Vivien Fletcher; Marco Scocchi; Graham C Walker; GP Ferguson
Essential role for the BacA protein in the uptake of a truncated eukaryotic peptide in Sinorhizobium meliloti.
Journal of bacteriology 2009;191(5):1519-27.
2008: Roberto Aquilani; Marco Scocchi; Paolo Iadarola; Piero Franciscone; Manuela Verri; Federica Boschi; evasio pasini; Simona Viglio
Protein supplementation may enhance the spontaneous recovery of neurological alterations in patients with ischaemic stroke.
Clinical rehabilitation 2008;22(12):1042-50.
2008: Roberto Aquilani; Marco Scocchi; Federica Boschi; Simona Viglio; Paolo Iadarola; Ornella Pastoris; Manuela Verri
Effect of calorie-protein supplementation on the cognitive recovery of patients with subacute stroke.
Nutritional neuroscience 2008;11(5):235-40.
2008: Marco Scocchi; Maura Mattiuzzo; Monica Benincasa; Nikolinka Antcheva; Alessandro Tossi; Renato Gennaro
Investigating the mode of action of proline-rich antimicrobial peptides using a genetic approach: a tool to identify new bacterial targets amenable to the design of novel antibiotics.
Methods in molecular biology (Clifton, N.J.) 2008;494():161-76.
2007: Maura Mattiuzzo; Antonella Bandiera; Renato Gennaro; Monica Benincasa; Sabrina Pacor; Nikolinka Antcheva; Marco Scocchi
Role of the Escherichia coli SbmA in the antimicrobial activity of proline-rich peptides.
Molecular microbiology 2007;66(1):151-63.
2006: Elena Podda; Monica Benincasa; Sabrina Pacor; Fulvio Micali; Maura Mattiuzzo; Renato Gennaro; Marco Scocchi
Dual mode of action of Bac7, a proline-rich antibacterial peptide.
Biochimica et biophysica acta 2006;1760(11):1732-40.
2006: Monica Benincasa; Marco Scocchi; Sabrina Pacor; Alessandro Tossi; Donatella Nobili; Giancarlo Basaglia; Marina Busetti; Renato Gennaro
Fungicidal activity of five cathelicidin peptides against clinically isolated yeasts.
The Journal of antimicrobial chemotherapy 2006;58(5):950-9.
2005: Marco Scocchi; Igor Zelezetsky; Monica Benincasa; Renato Gennaro; Andrea Mazzoli; Alessandro Tossi
Structural aspects and biological properties of the cathelicidin PMAP-36.
The FEBS journal 2005;272(17):4398-406.
2004: Monica Benincasa; Marco Scocchi; Elena Podda; Barbara Skerlavaj; Lucilla Dolzani; Renato Gennaro
Antimicrobial activity of Bac7 fragments against drug-resistant clinical isolates.
Peptides 2004;25(12):2055-61.
2004: Linda Tomasinsig; Marco Scocchi; Romina Mettulio; Margherita Zanetti
Genome-wide transcriptional profiling of the Escherichia coli response to a proline-rich antimicrobial peptide.
Antimicrobial agents and chemotherapy 2004;48(9):3260-7.
2004: Roberto Aquilani; Manuela Verri; Paolo Iadarola; Patrizia Arcidiaco; Federica Boschi; Maurizia Dossena; Paolo Sessarego; Marco Scocchi; Nadia Arrigoni; Ornella Pastoris
Plasma precursors of brain catecholaminergic and serotonergic neurotransmitters in rehabilitation patients with ischemic stroke.
Archives of physical medicine and rehabilitation 2004;85(5):779-84.
2002: Linda Tomasinsig; Marco Scocchi; Carla Di Loreto; Daria Artico; Margherita Zanetti
Inducible expression of an antimicrobial peptide of the innate immunity in polymorphonuclear leukocytes.
Journal of leukocyte biology 2002;72(5):1003-10.
2001: Barbara Skerlavaj; Marco Scocchi; Renato Gennaro; Angela Risso; Margherita Zanetti
Structural and functional analysis of horse cathelicidin peptides.
Antimicrobial agents and chemotherapy 2001;45(3):715-22.
2000: Margherita Zanetti; Renato Gennaro; Marco Scocchi; Barbara Skerlavaj
Structure and biology of cathelicidins.
Advances in experimental medicine and biology 2000;479():203-18.
1999: Marco Scocchi; D Bontempo; Sabrina Boscolo; Linda Tomasinsig; E Giulotto; Margherita Zanetti
Novel cathelicidins in horse leukocytes(1).
FEBS letters 1999;457(3):459-64.
1998: Renato Gennaro; Marco Scocchi; L Merluzzi; Margherita Zanetti
Biological characterization of a novel mammalian antimicrobial peptide.
Biochimica et biophysica acta 1998;1425(2):361-8.
1998: Marco Scocchi; S Wang; Renato Gennaro; Margherita Zanetti
Cloning and analysis of a transcript derived from two contiguous genes of the cathelicidin family.
Biochimica et biophysica acta 1998;1398(3):393-6.
1997: Marco Scocchi; S Wang; Margherita Zanetti
Structural organization of the bovine cathelicidin gene family and identification of a novel member.
FEBS letters 1997;417(3):311-5.
1997: Alessandro Tossi; Marco Scocchi; Margherita Zanetti; Renato Gennaro; P Storici; Domenico Romeo
An approach combining rapid cDNA amplification and chemical synthesis for the identification of novel, cathelicidin-derived, antimicrobial peptides.
Methods in molecular biology (Clifton, N.J.) 1997;78():133-50.
1995: L Bagella; Marco Scocchi; Margherita Zanetti
cDNA sequences of three sheep myeloid cathelicidins.
FEBS letters 1995;376(3):225-8.
1995: Alessandro Tossi; Marco Scocchi; Margherita Zanetti; P Storici; Renato Gennaro
PMAP-37, a novel antibacterial peptide from pig myeloid cells. cDNA cloning, chemical synthesis and activity.
European journal of biochemistry / FEBS 1995;228(3):941-6.
1994: Marco Scocchi; Domenico Romeo; Margherita Zanetti
Molecular cloning of Bac7, a proline- and arginine-rich antimicrobial peptide from bovine neutrophils.
FEBS letters 1994;352(2):197-200.
1994: Margherita Zanetti; P Storici; Alessandro Tossi; Marco Scocchi; Renato Gennaro
Molecular cloning and chemical synthesis of a novel antibacterial peptide derived from pig myeloid cells.
The Journal of biological chemistry 1994;269(11):7855-8.
1994: Alessandro Tossi; Marco Scocchi; B Skerlavaj; Renato Gennaro
Identification and characterization of a primary antibacterial domain in CAP18, a lipopolysaccharide binding protein from rabbit leukocytes.
FEBS letters 1994;339(1-2):108-12.
1994: P Storici; Marco Scocchi; Alessandro Tossi; Renato Gennaro; Margherita Zanetti
Chemical synthesis and biological activity of a novel antibacterial peptide deduced from a pig myeloid cDNA.
FEBS letters 1994;337(3):303-7.
1993: Marco Scocchi; Domenico Romeo; Marina Cinco
Antimicrobial activity of two bactenecins against spirochetes.
Infection and immunity 1993;61(7):3081-3.
1992: Marco Scocchi; B Skerlavaj; Domenico Romeo; Renato Gennaro
Proteolytic cleavage by neutrophil elastase converts inactive storage proforms to antibacterial bactenecins.
European journal of biochemistry / FEBS 1992;209(2):589-95.