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Julià Blanco

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HIV-1

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Maria T Rodriguez-Plata; Maria C Puertas; Isabel Puigdomènech; Julià Blanco; Jorge Carrillo; Bonaventura Clotet; Itziar Erkizia; Nuria Izquierdo-Useros; Javier Martinez-Picado
The infectious synapse formed between mature dendritic cells and CD4+ T cells is independent of the presence of the HIV-1 envelope glycoprotein.
Anuska Llano; Silvia Marfil; Beatriz Mothe; Lidia Ruiz; Víctor Sánchez; Eloísa Yuste; Julià Blanco; Jorge Carrillo; Bonaventura Clotet; Elisabet García; Christian Brander
Expansion of antibody secreting cells and modulation of neutralizing antibody activity in HIV infected individuals undergoing structured treatment interruptions.
Marta Massanella; Eugenia Negredo; Núria Pérez-Álvarez; Maria Carmen Puertas; Jordi Puig; Maria J Buzón; Jorge Carrillo; Bonaventura Clotet; Javier Martínez-Picado; Julià Blanco
Raltegravir intensification shows differing effects on CD8 and CD4 T cells in HIV-infected HAART-suppressed individuals with poor CD4 T-cell recovery.

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All Publications

2013: Maria T Rodriguez-Plata; Maria C Puertas; Isabel Puigdomènech; Julià Blanco; Jorge Carrillo; Bonaventura Clotet; Itziar Erkizia; Nuria Izquierdo-Useros; Javier Martinez-Picado
The infectious synapse formed between mature dendritic cells and CD4+ T cells is independent of the presence of the HIV-1 envelope glycoprotein.
Retrovirology 2013;10():42.
2013: Anuska Llano; Silvia Marfil; Beatriz Mothe; Lidia Ruiz; Víctor Sánchez; Eloísa Yuste; Julià Blanco; Jorge Carrillo; Bonaventura Clotet; Elisabet García; Christian Brander
Expansion of antibody secreting cells and modulation of neutralizing antibody activity in HIV infected individuals undergoing structured treatment interruptions.
Journal of translational medicine 2013;11():48.
2012: Marta Massanella; Eugenia Negredo; Núria Pérez-Álvarez; Maria Carmen Puertas; Jordi Puig; Maria J Buzón; Jorge Carrillo; Bonaventura Clotet; Javier Martínez-Picado; Julià Blanco
Raltegravir intensification shows differing effects on CD8 and CD4 T cells in HIV-infected HAART-suppressed individuals with poor CD4 T-cell recovery.
AIDS (London, England) 2012;26(18):2285-93.
2012: Francesc Cunyat; Marta Curriu; Elisabet García; Silvia Marfil; Julià Blanco; Bonaventura Clotet; Cecilia Cabrera
Evaluation of the cytopathicity (fusion/hemifusion) of patient-derived HIV-1 envelope glycoproteins comparing two effector cell lines.
Journal of biomolecular screening 2012;17(6):727-37.
2012: Marta Curriu; Elisabet Garcia; Marta Massanella; Ruth Peña; Peter Wienberg; Joan Areal; Julià Blanco; Margarita Bofill; Cristina Carrato; Jorge Carrillo; Bonaventura Clotet; Francesc Cunyat; Cecilia Cabrera
Susceptibility of human lymphoid tissue cultured ex vivo to xenotropic murine leukemia virus-related virus (XMRV) infection.
PloS one 2012;7(5):e37415.
2012: Francesc Cunyat; Marta Curriu; Elisabet García; Silvia Marfil; Nuria Pérez-Alvárez; Carlo Federico Perno; Valentina Svicher; Julià Blanco; Bonaventura Clotet; Cecilia Cabrera
The HR2 polymorphism N140I in the HIV-1 gp41 combined with the HR1 V38A mutation is associated with a less cytopathic phenotype.
Retrovirology 2012;9():15.
2012: Marta Curriu; Patrice Debré; Hughes Fausther-Bovendo; Cecilio López-Galíndez; Marta Massanella; María Pernas; Vincent Vieillard; Cecilia Cabrera; Jorge Carrillo; Bonaventura Clotet; Julià Blanco
Viremic HIV infected individuals with high CD4 T cells and functional envelope proteins show anti-gp41 antibodies with unique specificity and function.
PloS one 2012;7(2):e30330.
2012: Josep M Llibre; Javier Martinez-Picado; Marta Massanella; Sarah Palmer; Maria C Puertas; Mario Stevenson; Viktor Dahl; Pere Domingo; Anna Esteve; Josep M Gatell; Mar Gutierrez; Maria Larrouse; Julià Blanco; Maria J Buzón; Bonaventura Clotet
Treatment intensification with raltegravir in subjects with sustained HIV-1 viraemia suppression: a randomized 48-week study.
Antiviral therapy 2012;17(2):355-64.
2011: Maria J Buzón; Bonaventura Clotet; Francisco M Codoñer; Judith Dalmau; Simon D W Frost; Josep M Llibre; Marta Massanella; Roger Paredes; Christian Pou; Maria C Puertas; Mario Stevenson; Julià Blanco; Javier Martinez-Picado
Deep molecular characterization of HIV-1 dynamics under suppressive HAART.
PLoS pathogens 2011;7(10):e1002314.
2011: Sonsoles Sánchez-Palomino; Eloísa Yuste; José Alcamí; Margarita Bofill; Jorge Carrillo; Bonaventura Clotet; Ana García; Felipe García; Josep M Gatell; Nuria González; Marta Massanella; Alberto Merino; Julià Blanco
A cell-to-cell HIV transfer assay identifies humoral responses with broad neutralization activity.
Vaccine 2011;29(32):5250-9.
2011: Jonathan Barroso-González; Julià Blanco; Laura de Armas-Rillo; Laura García-Expósito; José D Machado; Isabel Puigdomènech; Agustín Valenzuela-Fernández
Viral infection: Moving through complex and dynamic cell-membrane structures.
Communicative & integrative biology 2011;4(4):398-408.
2011: Montserrat Plana; Felipe Garcia; Laila Darwich; Joan Romeu; Anna López; Cecilia Cabrera; Marta Massanella; Esther Canto; Raul Ruiz-Hernandez; Julià Blanco; Marcelo Sánchez; Josep M Gatell; Bonaventura Clotet; Lidia Ruiz; Margarita Bofill
The reconstitution of the thymus in immunosuppressed individuals restores CD4-specific cellular and humoral immune responses.
Immunology 2011;133(3):318-28.
2011: Margalida Rotger; Judith Dalmau; Andri Rauch; Paul McLaren; Steven E Bosinger; Raquel Martinez; Netanya G Sandler; Annelys Roque; Julia Liebner; Manuel Battegay; Enos Bernasconi; Patrick Descombes; Itziar Erkizia; Jacques Fellay; Bernard Hirschel; Jose M Miró; Eduard Palou; Matthias Hoffmann; Marta Massanella; Julià Blanco; Matthew Woods; Huldrych F Günthard; Paul de Bakker; Daniel C Douek; Guido Silvestri; Javier Martinez-Picado; Amalio Telenti
Comparative transcriptomics of extreme phenotypes of human HIV-1 infection and SIV infection in sooty mangabey and rhesus macaque.
The Journal of clinical investigation 2011;121(6):2391-400.
2011: I Galindo-Cardiel; M Fernández-Jiménez; L Luján; J Buesa; J Espada; E Fantova; Julià Blanco; Segales Joaquim; Ignacio Badiola
Novel group A rotavirus G8 P[1] as primary cause of an ovine diarrheic syndrome outbreak in weaned lambs.
Veterinary microbiology 2011;149(3-4):467-71.
2011: Laura García-Expósito; Jonathan Barroso-González; Isabel Puigdomènech; José-David Machado; Julià Blanco; Agustín Valenzuela-Fernández
HIV-1 requires Arf6-mediated membrane dynamics to efficiently enter and infect T lymphocytes.
Molecular biology of the cell 2011;22(8):1148-66.
2011: Nuria Izquierdo-Useros; Maria Carmen Puertas; Francesc E Borras; Julià Blanco; Javier Martinez-Picado
Exosomes and retroviruses: the chicken or the egg?
Cellular microbiology 2011;13(1):10-7.
2010: Eugenia Negredo; Marta Massanella; Jordi Puig; Núria Pérez-Alvarez; José Miguel Gallego-Escuredo; Joan Villarroya; Francesc Villarroya; José Moltó; José Ramón Santos; Bonaventura Clotet; Julià Blanco
Nadir CD4 T cell count as predictor and high CD4 T cell intrinsic apoptosis as final mechanism of poor CD4 T cell recovery in virologically suppressed HIV-infected patients: clinical implications.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2010;50(9):1300-8.
2010: Marta Massanella; Eugenia Negredo; Núria Pérez-Alvarez; Jordi Puig; Raul Ruiz-Hernández; Margarita Bofill; Bonaventura Clotet; Julià Blanco
CD4 T-cell hyperactivation and susceptibility to cell death determine poor CD4 T-cell recovery during suppressive HAART.
AIDS (London, England) 2010;24(7):959-68.
2010: Maria J Buzón; Marta Massanella; Josep M Llibre; Anna Esteve; Viktor Dahl; Maria C Puertas; Josep M Gatell; Pere Domingo; Roger Paredes; Mark E Sharkey; Sarah Palmer; Mario Stevenson; Bonaventura Clotet; Julià Blanco; Javier Martinez-Picado
HIV-1 replication and immune dynamics are affected by raltegravir intensification of HAART-suppressed subjects.
Nature medicine 2010;16(4):460-5.
2010: Nuria Izquierdo-Useros; Mar Naranjo-Gómez; Itziar Erkizia; Maria Carmen Puertas; Francesc E Borras; Julià Blanco; Javier Martinez-Picado
HIV and mature dendritic cells: Trojan exosomes riding the Trojan horse?
PLoS pathogens 2010;6(3):e1000740.
2010: Marta Massanella; Cristina Tural; Laura Papagno; Elisabet Garcia; Antoni Jou; Margarita Bofill; Brigitte Autran; Bonaventura Clotet; Julià Blanco
Changes in T-cell subsets in HIV-HCV-coinfected patients during pegylated interferon-alpha2a plus ribavirin treatment.
Antiviral therapy 2010;15(3):333-42.
2010: Anne Aucher; Isabel Puigdomènech; Etienne Joly; Bonaventura Clotet; Denis Hudrisier; Julià Blanco
Could CD4 capture by CD8+ T cells play a role in HIV spreading?
Journal of biomedicine & biotechnology 2010;2010():907371.
2009: Isabel Puigdomènech; Marta Massanella; Cecilia Cabrera; Bonaventura Clotet; Julià Blanco
On the steps of cell-to-cell HIV transmission between CD4 T cells.
Retrovirology 2009;6():89.
2008: Eugenia Negredo; Isabel Puigdomènech; Silvia Marfil; Jordi Puig; Núria Pérez-Alvarez; Lidia Ruiz; Celestino Rey-Joly; Bonaventura Clotet; Julià Blanco
Association between HIV replication and cholesterol in peripheral blood mononuclear cells in HIV-infected patients interrupting HAART.
The Journal of antimicrobial chemotherapy 2008;61(2):400-4.
2008: Isabel Puigdomènech; Marta Massanella; Nuria Izquierdo-Useros; Raul Ruiz-Hernandez; Marta Curriu; Margarita Bofill; Javier Martinez-Picado; Manel Juan; Bonaventura Clotet; Julià Blanco
HIV transfer between CD4 T cells does not require LFA-1 binding to ICAM-1 and is governed by the interaction of HIV envelope glycoprotein with CD4.
Retrovirology 2008;5():32.
2006: Gemma Coma; Ruth Peña; Julià Blanco; A Rosell; Francesc E Borras; José A Esté; Bonaventura Clotet; Lidia Ruiz; R Michael E Parkhouse; Margarita Bofill
Treatment of monocytes with interleukin (IL)-12 plus IL-18 stimulates survival, differentiation and the production of CXC chemokine ligands (CXCL)8, CXCL9 and CXCL10.
Clinical and experimental immunology 2006;145(3):535-44.
2006: Berta Bosch; Imma Clotet-Codina; Julià Blanco; Eduardo Pauls; Gemma Coma; Samandhy Cedeño; Francesc Mitjans; Anuska Llano; Margarita Bofill; Bonaventura Clotet; Jaume Piulats; José A Esté
Inhibition of human immunodeficiency virus type 1 infection in macrophages by an alpha-v integrin blocking antibody.
Antiviral research 2006;69(3):173-80.
2006: Eugenia Negredo; Bonaventura Clotet; Jordi Puig; Núria Pérez-Alvarez; Lidia Ruiz; Joan Romeu; José Moltó; Celestino Rey-Joly; Julià Blanco
The effect of atorvastatin treatment on HIV-1-infected patients interrupting antiretroviral therapy.
AIDS (London, England) 2006;20(4):619-21.
2005: Berta Bosch; Julià Blanco; Eduardo Pauls; Imma Clotet-Codina; Mercedes Armand-Ugón; Boyan Grigorov; Delphine Muriaux; Bonaventura Clotet; Jean-Luc Darlix; José A Esté
Inhibition of coreceptor-independent cell-to-cell human immunodeficiency virus type 1 transmission by a CD4-immunoglobulin G2 fusion protein.
Antimicrobial agents and chemotherapy 2005;49(10):4296-304.
2005: Julià Blanco; Imma Clotet-Codina; Berta Bosch; Mercedes Armand-Ugón; Bonaventura Clotet; José A Esté
Multiparametric assay to screen and dissect the mode of action of anti-human immunodeficiency virus envelope drugs.
Antimicrobial agents and chemotherapy 2005;49(9):3926-9.
2004: Julià Blanco; Berta Bosch; Maria Teresa Fernández-Figueras; Jordi Barretina; Bonaventura Clotet; José A Esté
High level of coreceptor-independent HIV transfer induced by contacts between primary CD4 T cells.
The Journal of biological chemistry 2004;279(49):51305-14.
2004: Julià Blanco; Jordi Barretina; Bonaventura Clotet; José A Esté
R5 HIV gp120-mediated cellular contacts induce the death of single CCR5-expressing CD4 T cells by a gp41-dependent mechanism.
Journal of leukocyte biology 2004;76(4):804-11.
2004: Jordi Barretina; Julià Blanco; Anna Bonjoch; Anuska Llano; Bonaventura Clotet; José A Esté
Immunological and virological study of enfuvirtide-treated HIV-positive patients.
AIDS (London, England) 2004;18(12):1673-82.
2003: Jordi Barretina; J Juncà; Anuska Llano; Arantxa Gutiérrez; A Flores; Julià Blanco; Bonaventura Clotet; José A Esté
CXCR4 and SDF-1 expression in B-cell chronic lymphocytic leukemia and stage of the disease.
Annals of hematology 2003;82(8):500-5.
2003: Jordi Barretina; Julià Blanco; Mercedes Armand-Ugón; Arantxa Gutiérrez; Bonaventura Clotet; José A Esté
Anti-HIV-1 activity of enfuvirtide (T-20) by inhibition of bystander cell death.
Antiviral therapy 2003;8(2):155-61.
2003: Mercedes Armand-Ugón; Miguel E Quiñones-Mateu; Arantxa Gutiérez; Jordi Barretina; Julià Blanco; Dominique Schols; Erik De Clercq; Bonaventura Clotet; José A Esté
Reduced fitness of HIV-1 resistant to CXCR4 antagonists.
Antiviral therapy 2003;8(1):1-8.
2003: Julià Blanco; Jordi Barretina; Karine F Ferri; Etienne Jacotot; Arantxa Gutiérrez; Mercedes Armand-Ugón; Cecilia Cabrera; Guido Kroemer; Bonaventura Clotet; José A Esté
Cell-surface-expressed HIV-1 envelope induces the death of CD4 T cells during GP41-mediated hemifusion-like events.
Virology 2003;305(2):318-29.
2002: Miguel Angel Martínez; Arantxa Gutiérrez; Mercedes Armand-Ugón; Julià Blanco; Mariona Parera; Jordi Gómez; Bonaventura Clotet; José A Esté
Suppression of chemokine receptor expression by RNA interference allows for inhibition of HIV-1 replication.
AIDS (London, England) 2002;16(18):2385-90.
2002: Maria Castedo; Thomas Roumier; Julià Blanco; Karine F Ferri; Jordi Barretina; lionel tintignac; Karine Andreau; Jean-Luc PERFETTINI; Alessandra Amendola; Roberta Nardacci; Philip Leduc; Donald Ingber; Sabine Druillennec; Bernard P Roques; Serge Leibovitch; Montserrat Vilella-Bach; Jie Chen; José A Este; Nazanine Modjtahedi; Mauro Piacentini; Guido Kroemer
Sequential involvement of Cdk1, mTOR and p53 in apoptosis induced by the HIV-1 envelope.
The EMBO journal 2002;21(15):4070-80.
2002: Julià Blanco; Jordi Barretina; Arantxa Gutiérrez; Mercedes Armand-Ugón; Cecilia Cabrera; Bonaventura Clotet; José A Esté
Preferential attachment of HIV particles to activated and CD45RO+CD4+ T cells.
AIDS research and human retroviruses 2002;18(1):27-38.
2002: Cecilia Cabrera; Arantxa Gutiérrez; Jordi Barretina; Julià Blanco; Alexander Litovchick; Aviva Lapidot; Bonaventura Clotet; José A Esté
Anti-HIV activity of a novel aminoglycoside-arginine conjugate.
Antiviral research 2002;53(1):1-8.
2001: Anuska Llano; Jordi Barretina; Arantxa Gutiérrez; Julià Blanco; Cecilia Cabrera; Bonaventura Clotet; José A Esté
Interleukin-7 in plasma correlates with CD4 T-cell depletion and may be associated with emergence of syncytium-inducing variants in human immunodeficiency virus type 1-positive individuals.
Journal of virology 2001;75(21):10319-25.
2001: Maria Castedo; Karine F Ferri; Julià Blanco; Thomas Roumier; Nathanael Larochette; Jordi Barretina; Alessandra Amendola; Roberta Nardacci; Didier Métivier; J A Este; Mauro Piacentini; Guido Kroemer
Human immunodeficiency virus 1 envelope glycoprotein complex-induced apoptosis involves mammalian target of rapamycin/FKBP12-rapamycin-associated protein-mediated p53 phosphorylation.
The Journal of experimental medicine 2001;194(8):1097-110.
2001: Anuska Llano; Jordi Barretina; Julià Blanco; Arantxa Gutiérrez; Bonaventura Clotet; José A Esté
Stromal-cell-derived factor 1 prevents the emergence of the syncytium-inducing phenotype of HIV-1 in vivo.
AIDS (London, England) 2001;15(14):1890-2.
2001: Julià Blanco; Jordi Barretina; Cecilia Cabrera; Arantxa Gutiérrez; Bonaventura Clotet; José A Esté
CD4(+) and CD8(+) T cell death during human immunodeficiency virus infection in vitro.
Virology 2001;285(2):356-65.
2000: Karine F Ferri; Etienne Jacotot; Julià Blanco; José A Esté; Naoufal Zamzami; Santos A Susin; Z Xie; Greg M Brothers; JC Reed; Josef M Penninger; Guido Kroemer
Apoptosis control in syncytia induced by the HIV type 1-envelope glycoprotein complex: role of mitochondria and caspases.
The Journal of experimental medicine 2000;192(8):1081-92.
2000: Cecilia Cabrera; Arantxa Gutiérrez; Julià Blanco; Jordi Barretina; Alexander Litovchick; Aviva Lapidot; AG Evdokimov; Bonaventura Clotet; José A Esté
Anti-human immunodeficiency virus activity of novel aminoglycoside-arginine conjugates at early stages of infection.
AIDS research and human retroviruses 2000;16(7):627-34.
2000: Karine F Ferri; Etienne Jacotot; Julià Blanco; José A Esté; Guido Kroemer
Mitochondrial control of cell death induced by HIV-1-encoded proteins.
Annals of the New York Academy of Sciences 2000;926():149-64.
2000: Julià Blanco; Jordi Barretina; Geoffrey Henson; Gary J Bridger; Erik De Clercq; Bonaventura Clotet; José A Esté
The CXCR4 antagonist AMD3100 efficiently inhibits cell-surface-expressed human immunodeficiency virus type 1 envelope-induced apoptosis.
Antimicrobial agents and chemotherapy 2000;44(1):51-6.
1999: José A Esté; C Cabrera; Julià Blanco; A Gutierrez; Gary J Bridger; Geoffrey Henson; Bonaventura Clotet; Dominique Schols; Erik De Clercq
Shift of clinical human immunodeficiency virus type 1 isolates from X4 to R5 and prevention of emergence of the syncytium-inducing phenotype by blockade of CXCR4.
Journal of virology 1999;73(7):5577-85.
1999: Julià Blanco; Etienne Jacotot; C Cabrera; A Cardona; Bonaventura Clotet; Erik De Clercq; José A Esté
The implication of the chemokine receptor CXCR4 in HIV-1 envelope protein-induced apoptosis is independent of the G protein-mediated signalling.
AIDS (London, England) 1999;13(8):909-17.
1999: Julià Blanco; C Cabrera; A Jou; L Ruiz; Bonaventura Clotet; José A Esté
Chemokine and chemokine receptor expression after combined anti-HIV-1 interleukin-2 therapy.
AIDS (London, England) 1999;13(5):547-55.