FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

David Scott

Research Profile

Physiology

Anatomy

Living Beings

Chemicals & Drugs

Procedures

Genetic Therapy

Co-author Network

Publications

TOP 3
Leslie P Cousens; Wassim Elyaman; Katherine High; Samia J Khoury; Bruce Mazer; Timothy J Messitt; Federico Mingozzi; Leonard Moise; Nader Najafian; Mohamed Sayegh; David W Scott; Yan Su; Anne S De Groot
In vitro and in vivo studies of IgG-derived Treg epitopes (Tregitopes): a promising new tool for tolerance induction and treatment of autoimmunity.
D Yu; Xiaoguo H Zhan; Xianfeng Frank Zhao; J Zhu; Gregory Carey; Srujana Cherukuri; Curt I Civin; Y Guo; David W Scott; E Smith; Mark S Williams; Steven Zhan
Mice deficient in MIM expression are predisposed to lymphomagenesis.
David W Scott; Ai-Hong Zhang; Yan Su
B-cell based gene therapy for autoimmune diseases.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of David Scott (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Leslie P Cousens; Wassim Elyaman; Katherine High; Samia J Khoury; Bruce Mazer; Timothy J Messitt; Federico Mingozzi; Leonard Moise; Nader Najafian; Mohamed Sayegh; David W Scott; Yan Su; Anne S De Groot
In vitro and in vivo studies of IgG-derived Treg epitopes (Tregitopes): a promising new tool for tolerance induction and treatment of autoimmunity.
Journal of clinical immunology 2013;33 Suppl 1():S43-9.
2012: D Yu; Xiaoguo H Zhan; Xianfeng Frank Zhao; J Zhu; Gregory Carey; Srujana Cherukuri; Curt I Civin; Y Guo; David W Scott; E Smith; Mark S Williams; Steven Zhan
Mice deficient in MIM expression are predisposed to lymphomagenesis.
Oncogene 2012;31(30):3561-8.
2012: David W Scott; Ai-Hong Zhang; Yan Su
B-cell based gene therapy for autoimmune diseases.
Infectious disorders drug targets 2012;12(3):241-7.
2012: Melanie P Matheu; Ian Parker; David W Scott; Yan Su; Caroline A Blanc; Milton L Greenberg; Michael D Cahalan
Toll-like receptor 4-activated B cells out-compete Toll-like receptor 9-activated B cells to establish peripheral immunological tolerance.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(20):E1258-66.
2012: Qixin Shi; Donna L Farber; Jason R Lees; David W Scott; Stephen T Bartlett
Endogenous expansion of regulatory T cells leads to long-term islet graft survival in diabetic NOD mice.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2012;12(5):1124-32.
2012: Leonard Moise; Anne S De Groot; William D Martin; Chang Song; Ryan Tassone; David W Scott
Effect of HLA DR epitope de-immunization of Factor VIII in vitro and in vivo.
Clinical immunology (Orlando, Fla.) 2012;142(3):320-31.
2012: David W Scott; Jay N Lozier
Gene therapy for haemophilia: prospects and challenges to prevent or reverse inhibitor formation.
British journal of haematology 2012;156(3):295-302.
2012: Robert J Rossi; Belinda M Jackson; Ai-Hong Zhang; David W Scott
Tolerance induction via B-cell delivered gene therapy.
Methods in molecular biology (Clifton, N.J.) 2012;900():471-87.
2011: Yan Su; Ai-Hong Zhang; Xin Li; Nana Owusu-Boaitey; Jonathan Skupsky; David W Scott
B cells "transduced" with TAT-fusion proteins can induce tolerance and protect mice from diabetes and EAE.
Clinical immunology (Orlando, Fla.) 2011;140(3):260-7.
2011: David W Scott
Transduced B cells: B is for 'beneficial'!
European journal of immunology 2011;41(6):1528-30.
2011: David W Scott
Gene therapy for immunologic tolerance: using bone marrow-derived cells to treat autoimmunity and hemophilia.
Current stem cell research & therapy 2011;6(1):38-43.
2011: Ai-Hong Zhang; Jonathan Skupsky; David W Scott
Effect of B-cell depletion using anti-CD20 therapy on inhibitory antibody formation to human FVIII in hemophilia A mice.
Blood 2011;117(7):2223-6.
2011: Yan Su; Ai-Hong Zhang; Nancy Noben-Trauth; David W Scott
B-Cell Gene Therapy for Tolerance Induction: Host but Not Donor B-Cell Derived IL-10 is Necessary for Tolerance.
Frontiers in microbiology 2011;2():154.
2011: Miranda P Dierselhuis; Ellen Schrama; David W Scott; Eric Spierings
Gene therapy with IgG-HY fusion proteins to reduce male-specific T-cell reactivity in vitro.
Human gene therapy 2011;22(1):44-54.
2010: Jonathan Skupsky; Mark Saltis; Chang Song; Robert Rossi; Diane Nelson; David W Scott
Gene therapy for tolerance and vice versa: a case for hemophilia.
Current opinion in molecular therapeutics 2010;12(5):509-18.
2010: Ai-Hong Zhang; Xin Li; Olusegun O Onabajo; Yan Su; Jonathan Skupsky; James W Thomas; David W Scott
B-cell delivered gene therapy for tolerance induction: role of autoantigen-specific B cells.
Journal of autoimmunity 2010;35(2):107-13.
2010: David W Scott; Agnes M Azimzadeh
Transplantation tolerance: one --- step towards the holy grail.
Clinical immunology (Orlando, Fla.) 2010;136(2):161.
2010: Jonathan Skupsky; Ai-Hong Zhang; Yan Su; David W Scott
B-cell-delivered gene therapy induces functional T regulatory cells and leads to a loss of antigen-specific effector cells.
Molecular therapy : the journal of the American Society of Gene Therapy 2010;18(8):1527-35.
2010: David W Scott
Gene therapy for immunological tolerance: using 'transgenic' B cells to treat inhibitor formation.
Haemophilia : the official journal of the World Federation of Hemophilia 2010;16(102):89-94.
2010: David W Scott; A S De Groot
Can we prevent immunogenicity of human protein drugs?
Annals of the rheumatic diseases 2010;69 Suppl 1():i72-76.
2009: Jonathan Skupsky; Ai-Hong Zhang; Yan Su; David W Scott
A role for thrombin in the initiation of the immune response to therapeutic factor VIII.
Blood 2009;114(21):4741-8.
2009: David W Scott
T regulatory cells turn on T regulatory cells.
Blood 2009;114(19):3975-6.
2009: Ai Hong Zhang; Jonathan Skupsky; David W Scott
Factor VIII inhibitors: risk factors and methods for prevention and immune modulation.
Clinical reviews in allergy & immunology 2009;37(2):114-24.
2009: Frank Alderuccio; James Chan; David W Scott; Ban-Hock Toh
Gene therapy and bone marrow stem-cell transfer to treat autoimmune disease.
Trends in molecular medicine 2009;15(8):344-51.
2008: Anne S De Groot; Leonard Moise; Julie A McMurry; Erik Wambre; Laurence Van Overtvelt; Philippe Moingeon; David W Scott; William Martin
Activation of natural regulatory T cells by IgG Fc-derived peptide "Tregitopes".
Blood 2008;112(8):3303-11.
2008: Yan Su; Gregory Carey; Maja Maric; David W Scott
B cells induce tolerance by presenting endogenous peptide-IgG on MHC class II molecules via an IFN-gamma-inducible lysosomal thiol reductase-dependent pathway.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(2):1153-60.
2007: Anne S De Groot; David W Scott
Immunogenicity of protein therapeutics.
Trends in immunology 2007;28(11):482-90.
2007: Jonathan Skupsky; Yan Su; Tie Chi Lei; David W Scott
Tolerance induction by gene transfer to lymphocytes.
Current gene therapy 2007;7(5):369-80.
2007: Shailesh R Satpute; Nadejda Soukhareva; David W Scott; Kamal D Moudgil
Mycobacterial Hsp65-IgG-expressing tolerogenic B cells confer protection against adjuvant-induced arthritis in Lewis rats.
Arthritis and rheumatism 2007;56(5):1490-6.
2006: Nadejda Soukhareva; Yufei Jiang; David W Scott
Treatment of diabetes in NOD mice by gene transfer of Ig-fusion proteins into B cells: role of T regulatory cells.
Cellular immunology 2006;240(1):41-6.
2006: Biying Xu; Peter Haviernik; Lawrence A Wolfraim; Kevin D Bunting; David W Scott
Bone marrow transplantation combined with gene therapy to induce antigen-specific tolerance and ameliorate EAE.
Molecular therapy : the journal of the American Society of Gene Therapy 2006;13(1):42-8.
2006: Wei Liang; Zaruhi Karabekian; Mary J Mattapallil; Qihong Xu; Angelia M Viley; Rachel R Caspi; David W Scott
B-cell delivered gene transfer of human S-Ag-Ig fusion protein protects from experimental autoimmune uveitis.
Clinical immunology (Orlando, Fla.) 2006;118(1):35-41.
2005: Mary T Litzinger; Yan Su; Tie Chi Lei; Nadejda Soukhareva; David W Scott
Mechanisms of gene therapy for tolerance: B7 signaling is required for peptide-IgG gene-transferred tolerance induction.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(2):780-7.
2005: Tie Chi Lei; David W Scott
Induction of tolerance to factor VIII inhibitors by gene therapy with immunodominant A2 and C2 domains presented by B cells as Ig fusion proteins.
Blood 2005;105(12):4865-70.
2005: Tie Chi Lei; Yan Su; David W Scott
Tolerance induction via a B-cell delivered gene therapy-based protocol: optimization and role of the Ig scaffold.
Cellular immunology 2005;235(1):12-20.
2004: Lun Song; Jianan Wang; Renxi Wang; Ming Yu; Y Sun; Gencheng Han; Yong Li; Jiahua Qian; David W Scott; Y Kang; Nadejda Soukhareva; Beifen Shen
Retroviral delivery of GAD-IgG fusion construct induces tolerance and modulates diabetes: a role for CD4+ regulatory T cells and TGF-beta?
Gene therapy 2004;11(20):1487-96.
2004: Kathleen P Pratt; Jiahua Qian; Ekram Ellaban; David K Okita; Brenda M Diethelm-Okita; Bianca M Conti-Fine; David W Scott
Immunodominant T-cell epitopes in the factor VIII C2 domain are located within an inhibitory antibody binding site.
Thrombosis and haemostasis 2004;92(3):522-8.
2004: Biying Xu; David W Scott
A novel retroviral gene therapy approach to inhibit specific antibody production and suppress experimental autoimmune encephalomyelitis induced by MOG and MBP.
Clinical immunology (Orlando, Fla.) 2004;111(1):47-52.
2003: Jennifer A Hinshaw; Carolyn M Mueller; David W Scott; Mark S Williams
B cell receptor signaling mediates immediate protection from Fas-induced apoptosis upstream of caspase activation through an atypical protein kinase C isozyme and de novo protein synthesis.
European journal of immunology 2003;33(9):2490-500.
2002: Moustapha El-Amine; Jennifer A Hinshaw; David W Scott
In vivo induction of tolerance by an Ig peptide is not affected by the deletion of FcR or a mutated IgG Fc fragment.
International immunology 2002;14(7):761-6.
2002: Melo E. F. Marco; Jiahua Qian; Moustapha El-Amine; Rajeev K Agarwal; Nadejda Soukhareva; Yubin Kang; David W Scott
Gene transfer of Ig-fusion proteins into B cells prevents and treats autoimmune diseases.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(9):4788-95.
2002: Evgueni L Saenko; Natalya M Ananyeva; Diana Kouiavskaia; Alexey V Khrenov; J A M Anderson; Midori Shima; J Qian; David W Scott
Haemophilia A: effects of inhibitory antibodies on factor VIII functional interactions and approaches to prevent their action.
Haemophilia : the official journal of the World Federation of Hemophilia 2002;8(1):1-11.
2001: J Qian; Evgueni L Saenko; David W Scott
Co-stimulation blockade, hemophilic inhibitors and tolerance.
Thrombosis and haemostasis 2001;86(6):1343-4.
2001: Melo E. F. Marco; Moustapha El-Amine; L Tonnetti; L Fleischman; David W Scott
Gene therapeutic approaches to induction and maintenance of tolerance.
International reviews of immunology 2001;20(5):627-45.
2001: Moustapha El-Amine; Melo E. F. Marco; David W Scott
Gene therapy for tolerance and autoimmunity: soon to be fulfilled promises?
Clinical immunology (Orlando, Fla.) 2001;99(1):1-6.
2001: Gregory Carey; David W Scott
Role of phosphatidylinositol 3-kinase in anti-IgM- and anti-IgD-induced apoptosis in B cell lymphomas.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(3):1618-26.
2000: K Sharma; RX Wang; L Y Zhang; D L Yin; X Y Luo; J C Solomon; R F Jiang; K Markos; W Davidson; David W Scott; Y F Shi
Death the Fas way: regulation and pathophysiology of CD95 and its ligand.
Pharmacology & therapeutics 2000;88(3):333-47.
2000: Moustapha El-Amine; Melo E. F. Marco; Yubin Kang; H Nguyen; Jiahua Qian; David W Scott
Mechanisms of tolerance induction by a gene-transferred peptide-IgG fusion protein expressed in B lineage cells.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(10):5631-6.
2000: D Donjerković; David W Scott
Activation-induced cell death in B lymphocytes.
Cell research 2000;10(3):179-92.
2000: J Qian; Linda C Burkly; EP Smith; Janine L Ferrant; Leon Hoyer; David W Scott; Christian Haudenschild
Role of CD154 in the secondary immune response: the reduction of pre-existing splenic germinal centers and anti-factor VIII inhibitor titer.
European journal of immunology 2000;30(9):2548-54.
2000: Carolyn M Mueller; David W Scott
Distinct molecular mechanisms of Fas resistance in murine B lymphoma cells.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(4):1854-62.
2000: Gregory Carey; D Donjerković; Carolyn M Mueller; S Liu; Jennifer A Hinshaw; L Tonnetti; W Davidson; David W Scott
B-cell receptor and Fas-mediated signals for life and death.
Immunological reviews 2000;176():105-15.
2000: Rajeev K Agarwal; Y Kang; ELIAS ZAMBIDIS; David W Scott; Chi-Chao Chan; Rachel R Caspi
Retroviral gene therapy with an immunoglobulin-antigen fusion construct protects from experimental autoimmune uveitis.
The Journal of clinical investigation 2000;106(2):245-52.
2000: D Donjerković; Carolyn M Mueller; David W Scott
Steroid- and retinoid-mediated growth arrest and apoptosis in WEHI-231 cells: role of NF-kappaB, c-Myc and CKI p27(Kip1).
European journal of immunology 2000;30(4):1154-61.
2000: D Donjerkovic; David W Scott
Regulation of the G1 phase of the mammalian cell cycle.
Cell research 2000;10(1):1-16.
2000: D Donjerković; Gregory Carey; Carolyn M Mueller; S Liu; David W Scott
Life and death decisions in B1 lymphoma cells.
Current topics in microbiology and immunology 2000;252():151-9.
1999: D Donjerković; L Zhang; David W Scott
Regulation of p27Kip1 accumulation in murine B-lymphoma cells: role of c-Myc and calcium.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1999;10(10):695-704.
1999: Yubin Kang; Melo E. F. Marco; E Deng; Roland Tisch; Moustapha El-Amine; David W Scott
Induction of hyporesponsiveness to intact foreign protein via retroviral-mediated gene expression: the IgG scaffold is important for induction and maintenance of immune hyporesponsiveness.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(15):8609-14.
1998: Y Kang; E F Melo; David W Scott
An ongoing immune response to HIV envelope gp120 in human CD4-transgenic mice contributes to T cell decline upon intravenous administration of gp120.
European journal of immunology 1998;28(8):2253-64.
1997: Kurt Brorson; M Brunswick; S Ezhevsky; D G Wei; R Berg; David W Scott; Kathryn E Stein
xid affects events leading to B cell cycle entry.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(1):135-43.
1997: ELIAS ZAMBIDIS; A Kurup; David W Scott
Genetically transferred central and peripheral immune tolerance via retroviral-mediated expression of immunogenic epitopes in hematopoietic progenitors or peripheral B lymphocytes.
Molecular medicine (Cambridge, Mass.) 1997;3(3):212-24.
1997: ELIAS ZAMBIDIS; R K Barth; David W Scott
Both resting and activated B lymphocytes expressing engineered peptide-Ig molecules serve as highly efficient tolerogenic vehicles in immunocompetent adult recipients.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(5):2174-82.
1997: David W Scott; D Donjerković; B Maddox; S Ezhevsky; T Grdina
Role of c-myc and p27 in anti-IgM induced B-lymphoma apoptosis.
Current topics in microbiology and immunology 1997;224():103-12.
1996: David W Scott; Marinus C Lamers; Gabriele Köhler; C L Sidman; B Maddox; R Carsetti
Role of c-myc and CD45 in spontaneous and anti-receptor-induced apoptosis in adult murine B cells.
International immunology 1996;8(9):1375-85.
1996: B R Maddox; David W Scott
Differential susceptibility to anti-receptor induced apoptosis in adult murine B-cells: role of B1 cells.
Frontiers in bioscience : a journal and virtual library 1996;1():a39-45.
1996: ELIAS ZAMBIDIS; David W Scott
Epitope-specific tolerance induction with an engineered immunoglobulin.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(10):5019-24.
1996: David W Scott; T Grdina; Y Shi
T cells commit suicide, but B cells are murdered!
Journal of immunology (Baltimore, Md. : 1950) 1996;156(7):2352-6.
1996: S A Ezhevsky; H Toyoshima; Tony Hunter; David W Scott
Role of cyclin A and p27 in anti-IgM induced G1 growth arrest of murine B-cell lymphomas.
Molecular biology of the cell 1996;7(4):553-64.
1995: X R Yao; David W Scott
Independent signaling for growth arrest and apoptosis by Ig alpha and Ig beta subunits of the B-cell antigen receptor complex.
Annals of the New York Academy of Sciences 1995;766():96-8.
1995: X R Yao; H Flaswinkel; Michael Reth; David W Scott
Immunoreceptor tyrosine-based activation motif is required to signal pathways of receptor-mediated growth arrest and apoptosis in murine B lymphoma cells.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(2):652-61.
1995: L B Liou; A Colosia; R B Corley; S H Clarke; David W Scott
Differential susceptibility to tolerance induction in vitro of splenic B cells from several transgenic mouse lines. Role of B1 cells.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(12):6262-74.
1995: David W Scott
Multiple mechanisms of immunologic tolerance: novel approaches for unresponsiveness.
Advances in experimental medicine and biology 1995;386():209-20.
1995: L F Joseph; S Ezhevsky; David W Scott
Lymphoma models for B-cell activation and tolerance: anti-immunoglobulin M treatment induces growth arrest by preventing the formation of an active kinase complex which phosphorylates retinoblastoma gene product in G1.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1995;6(1):51-7.
1994: D R Green; David W Scott
Activation-induced apoptosis in lymphocytes.
Current opinion in immunology 1994;6(3):476-87.
1994: G Fischer; S C Kent; L Joseph; D R Green; David W Scott
Lymphoma models for B cell activation and tolerance. X. Anti-mu-mediated growth arrest and apoptosis of murine B cell lymphomas is prevented by the stabilization of myc.
The Journal of experimental medicine 1994;179(1):221-8.
1994: David W Scott; G L Warner; X R Yao; S C Kent
Pathways and regulation of B-cell responsiveness and tolerance.
Chemical immunology 1994;58():34-66.
1993: X R Yao; David W Scott
Antisense oligodeoxynucleotides to the blk tyrosine kinase prevent anti-mu-chain-mediated growth inhibition and apoptosis in a B-cell lymphoma.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(17):7946-50.
1993: X R Yao; David W Scott
Inhibition of protein tyrosine kinase activity by herbimycin A prevents anti-mu but not LPS-mediated cell cycle progression and differentiation of splenic B lymphocytes.
Cellular immunology 1993;149(2):364-75.
1993: X R Yao; David W Scott
Expression of protein tyrosine kinases in the Ig complex of anti-mu-sensitive and anti-mu-resistant B-cell lymphomas: role of the p55blk kinase in signaling growth arrest and apoptosis.
Immunological reviews 1993;132():163-86.
1993: A Gaur; X R Yao; David W Scott
B cell tolerance induction by cross-linking of membrane IgM, but not IgD, and synergy by cross-linking of both isotypes.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(5):1663-9.
1993: David W Scott
Analysis of B cell tolerance in vitro.
Advances in immunology 1993;54():393-425.
1992: X R Yao; David W Scott
Effect of priming with a thymus-independent antigen on susceptibility to B-cell tolerance.
Cellular immunology 1992;142(2):434-43.
1992: J E Alés-Martínez; E Cuende; A Gaur; David W Scott
Prevention of B cell clonal deletion and anergy by activated T cells and their lymphokines.
Seminars in immunology 1992;4(3):195-202.
1992: D M Brown; G L Warner; J E Alés-Martínez; David W Scott; Richard P Phipps
Prostaglandin E2 induces apoptosis in immature normal and malignant B lymphocytes.
Clinical immunology and immunopathology 1992;63(3):221-9.
1992: G L Warner; D O Nelson; David W Scott
Synergy between TGF-beta and anti-IgM in growth inhibition of CD5+ B-cell lymphomas.
Annals of the New York Academy of Sciences 1992;651():274-6.
1992: G L Warner; J W Ludlow; D A Nelson; A Gaur; David W Scott
Anti-immunoglobulin treatment of murine B-cell lymphomas induces active transforming growth factor beta but pRB hypophosphorylation is transforming growth factor beta independent.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1992;3(3):175-81.
1992: N R Klinman; J E Alés-Martínez; David W Scott
The parameters of B-cell inactivation in transgenic mice vs classical model studies.
Research in immunology 1992;143(3):279-85.
1992: J E Alés-Martinez; David W Scott; R P Phipps; J E Casnellie; Guido Kroemer; Carmen Martinez; L Pezzi
Cross-linking of surface IgM or IgD causes differential biological effects in spite of overlap in tyrosine (de)phosphorylation profile.
European journal of immunology 1992;22(3):845-50.
1992: L B Liou; G L Warner; David W Scott
Can peritoneal B cells be rendered unresponsive?
International immunology 1992;4(1):15-21.
1992: L A Wilson; J J Thompson; S Ohkawa; David W Scott
Characterization of "modified-self"-induced specific antibody hyporesponsiveness to herpes simplex virus.
Viral immunology 1992;5(2):113-22.
1991: G L Warner; A Gaur; David W Scott
A polyclonal model for B-cell tolerance. II. Linkage between signaling of B-cell egress from G0, class II upregulation and unresponsiveness.
Cellular immunology 1991;138(2):404-12.
1991: J E Alés-Martínez; L Silver; N LoCascio; David W Scott
Lymphoma models for B-cell activation and tolerance. IX. Efficient reversal of anti-Ig-mediated growth inhibition by an activated TH2 clone.
Cellular immunology 1991;135(2):402-9.
1991: J E Alés-Martínez; E Cuende; Carlos Martínez; R M Parkhouse; L Pezzi; David W Scott
Signalling in B cells.
Immunology today 1991;12(6):201-5.
1991: G L Warner; David W Scott
A polyclonal model for B cell tolerance. I. Fc-dependent and Fc-independent induction of nonresponsiveness by pretreatment of normal splenic B cells with anti-Ig.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(7):2185-91.
1990: J E Alés-Martínez; G L Warner; David W Scott
Lymphoma models for B cell activation and tolerance. VIII. Cross-desensitization by sIgM and sIgD and its effects on growth regulation by anti-isotype antibodies.
Cellular immunology 1990;127(2):527-34.
1989: L S Silver; David W Scott; H Quill
Suppression of antibody synthesis by CD4+ T cell clones and normal T cells stimulated with monoclonal anti-CD3 antibody.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(11):3448-54.
1989: G L Warner; S Davies; David W Scott
Cholera toxin-sensitive and insensitive signaling via surface Ig.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(2):458-63.
1989: David W Scott; J E Alés-Martínez; J H Chace; N J LoCascio; L Silver; G L Warner
Models of B-cell unresponsiveness.
Cold Spring Harbor symposia on quantitative biology 1989;54 Pt 2():899-905.
1989: J H Chace; David W Scott
The tolerance defect. Properties and fate of tolerant B cells in adult mice.
The Year in immunology 1989;4():181-92.
1989: David W Scott
Clonal nature of the immune response.
Immunology series 1989;43():127-43.
1988: J H Chace; David W Scott
Activation events in hapten-specific B cells from tolerant mice.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(10):3258-62.
1988: J E Alés-Martínez; G L Warner; David W Scott
Immunoglobulins D and M mediate signals that are qualitatively different in B cells with an immature phenotype.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(18):6919-23.
1988: G L Warner; David W Scott
Lymphoma models for B-cell activation and tolerance. VII. Pathways in anti-Ig-mediated growth inhibition and its reversal.
Cellular immunology 1988;115(1):195-203.
1988: J P Cogswell; Richard P Phipps; David W Scott
Role of self carriers in the immune response and tolerance. XI. Correlation of Ia expression and interleukin-1 production with delivery of immunogenic signals in vivo by hapten-modified accessory cell-like tumor lines.
Cellular immunology 1988;114(1):55-70.
1988: J P Cogswell; David W Scott
Role of self carriers in the immune response and tolerance. XII. Effect of epitope density and antigen-presenting cell phenotype on the presentation of hapten-modified self for the induction of immunity or tolerance in vitro.
Cellular immunology 1988;114(1):71-82.
1987: David W Scott; A O'Garra; D Warren; Gerry G B Klaus
Lymphoma models for B cell activation and tolerance. VI. Reversal of anti-Ig-mediated negative signaling by T cell-derived lymphokines.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(12):3924-9.
1987: David W Scott; J H Chace; G L Warner; A O'Garra; G G Klaus; H Quill
Role of T cell-derived lymphokines in two models of B-cell tolerance.
Immunological reviews 1987;99():153-71.
1987: P S Pillai; S D Reynolds; David W Scott; J Gauldie; D N Sauder
Role of epidermal cell thymocyte-activating factor in the proliferation and differentiation of murine B cells.
Journal of leukocyte biology 1987;42(3):222-9.
1987: Rick L Tarleton; David W Scott
Initial induction of immunity, followed by suppression of responses to parasite antigens during Trypanosoma cruzi infection of mice.
Parasite immunology 1987;9(5):579-89.
1987: B J Rup; David W Scott
Role of dextran-specific suppressor T cells in the regulation of the immune response by a reactive form of dextran.
Cellular immunology 1987;106(2):203-14.
1987: David W Scott; D Livnat; John C Whitin; S B Dillon; R Snyderman; C A Pennell
Lymphoma models for B cell activation and tolerance. V. Anti-Ig mediated growth inhibition is reversed by phorbol myristate acetate but does not involve changes in cytosolic free calcium.
The Journal of molecular and cellular immunology : JMCI 1987;3(2):109-20.
1987: B J Rup; David W Scott
VSV replication in normal and transformed T cells, an assay for T suppressor cell activation.
Cellular immunology 1987;104(1):190-4.
1986: C A Pennell; David W Scott
Lymphoma models for B cell activation and tolerance. IV. Growth inhibition by anti-Ig of CH31 and CH33 B lymphoma cells.
European journal of immunology 1986;16(12):1577-81.
1986: J P Cogswell; R P Phipps; David W Scott
Role of self carriers in the immune response and tolerance. X. A lymphoid dendritic-like tumor, P388AD.2, acts as a novel immunogenic carrier for hapten.
Journal of immunology (Baltimore, Md. : 1950) 1986;137(3):777-83.
1986: P S Pillai; S D Reynolds; J H Chace; David W Scott
Differential expression of a surface antigen recognized by a monoclonal antibody, J11d, on unprimed and primed B cells.
Journal of immunology (Baltimore, Md. : 1950) 1986;137(3):791-7.
1986: David W Scott; D Livnat; C A Pennell; P Keng
Lymphoma models for B cell activation and tolerance. III. Cell cycle dependence for negative signalling of WEHI-231 B lymphoma cells by anti-mu.
The Journal of experimental medicine 1986;164(1):156-64.
1986: C A Pennell; David W Scott
Models and mechanisms for signal transduction in B cells.
Immunologic research 1986;5(1):61-70.
1985: David W Scott; J Tuttle; D Livnat; W Haynes; J P Cogswell; P Keng
Lymphoma models for B-cell activation and tolerance. II. Growth inhibition by anti-mu of WEHI-231 and the selection and properties of resistant mutants.
Cellular immunology 1985;93(1):124-31.
1985: M Ling; D Livnat; P S Pillai; David W Scott
Lymphoma models for B cell activation and tolerance. I. Conditions for the anti-mu-dependent stimulation of growth in NBL, a nude B cell lymphoma.
Journal of immunology (Baltimore, Md. : 1950) 1985;134(3):1449-54.
1985: R B Corley; N J LoCascio; M Ovnic; LW Arnold; P S Pillai; David W Scott; G Haughton
Three classes of signalling molecules on B-cell membranes.
Journal of cellular biochemistry 1985;27(1):1-12.
1985: J P Cogswell; David W Scott
Accessory cell presentation of hapten-modified self.
Survey of immunologic research 1985;4(4):303-12.
1984: P S Pillai; David W Scott; D A White; R B Corley
Major histocompatibility complex-restricted and unrestricted interactions in the T cell-dependent activation of hapten-binding B cells.
Immunobiology 1984;166(4-5):345-59.
1984: R P Phipps; P S Pillai; David W Scott
Conversion of a tolerogenic to an immunogenic signal by P388AD.2 cells, a lymphoid dendritic cell-like tumor line.
Journal of immunology (Baltimore, Md. : 1950) 1984;132(5):2273-8.
1984: D S Pisetsky; S A Caster; M Piper; David W Scott; A D Steinberg
Cloning of B cells from autoimmune MRL-lpr/lpr and MRL.xid mice.
Cellular immunology 1984;84(1):32-40.
1984: L A Wilson; J M Karabin; J W Smith; D Dawson; David W Scott
Modified-self-induced modulation of the immune response to herpes simplex virus: effect on antibody formation, cytotoxic T lymphocyte induction, and survival.
Journal of immunology (Baltimore, Md. : 1950) 1984;132(3):1522-8.
1984: R P Phipps; David W Scott
Function of IgD in B cell triggering and tolerance: an overview of recent advances.
Survey of immunologic research 1984;3(2-3):195-7.
1984: David W Scott
Mechanisms in immune tolerance.
Critical reviews in immunology 1984;5(1):1-25.
1983: R P Phipps; David W Scott
A novel role for macrophages: the ability of macrophages to tolerize B cells.
Journal of immunology (Baltimore, Md. : 1950) 1983;131(5):2122-7.
1983: M Piper; P S Pillai; David W Scott
Hapten-specific murine colony-forming B cells. III. Delineation of functional B cell subpopulations grown under different conditions.
Journal of immunology (Baltimore, Md. : 1950) 1983;131(2):587-92.
1983: D L Toffaletti; T L Darrow; David W Scott
Augmentation of syngeneic tumor-specific immunity by semiallogeneic cell hybrids.
Journal of immunology (Baltimore, Md. : 1950) 1983;130(6):2982-6.
1983: P S Pillai; David W Scott
Cellular events in tolerance IX: maintenance of immunological tolerance in the presence of normal b-cell precursors and in the absence of demonstrable suppression.
Cellular immunology 1983;77(1):69-76.
1983: S J Anderson; David W Scott
Generation of antigen-responsive B-cell line by somatic cell hybridization.
Hybridoma 1983;2(2):211-8.
1983: B Grouix; David W Scott
Role of self carriers in the immune response and tolerance. VIII. Suppression of the MOPC-104E idiotypic response by idiotype-modified self, but not by dextran-modified self.
Journal of immunology (Baltimore, Md. : 1950) 1983;130(1):86-90.
1982: P S Pillai; David W Scott; M Piper; R B Corley
Effect of recent antigen exposure on the functional expression of B cell subpopulations.
Journal of immunology (Baltimore, Md. : 1950) 1982;129(3):1023-8.
1982: David W Scott; J Tuttle; P S Pillai; M Piper
Role of IgD in tolerance and cross-priming: IgD-related signals in B-cell growth, differentiation and tolerance.
Annals of the New York Academy of Sciences 1982;399():290-5.
1982: David W Scott; P S Pillai; S J Anderson; R B Corley
Regulation of growth and differentiation in B cell clones and hybrids.
Advances in experimental medicine and biology 1982;150():183-200.
1982: David W Scott; T L Darrow; B Grouix; L A Wilson
Recognition and regulation by modified self.
Annals of the New York Academy of Sciences 1982;392():1-8.
1981: P S Pillai; David W Scott
Hapten-specific murine colony-forming B cells. II. Delineation of a tolerogen-sensitive subpopulation of colony-forming B cells.
Journal of immunology (Baltimore, Md. : 1950) 1981;127(4):1603-6.
1981: Thomas J. Santoro; David W Scott; D S Pisetsky
The induction of tolerance and suppression in autoimmune MRL mice using hapten-modified self.
Journal of immunology (Baltimore, Md. : 1950) 1981;127(2):690-3.
1981: David W Scott; J Tuttle; M Piper
B-cell subsets responsive to fluorescein-conjugated antigens. IV. Cross-stimulation of B cells genetically unresponsive to LPS by hapten-conjugated lipopolysaccharide.
Cellular immunology 1981;61(2):292-9.
1981: P S Pillai; David W Scott
Hapten-specific murine colony-forming B cells: in vitro response of colonies to fluoresceinated thymus independent antigens.
Journal of immunology (Baltimore, Md. : 1950) 1981;126(5):1883-6.
1980: J T Li; David W Scott
Role of self carriers in the immune response and tolerance. VII. Importance of H-2 antigens in the in vitro induction of tolerance and suppression to hapten-modified self.
Journal of immunology (Baltimore, Md. : 1950) 1980;125(6):2385-90.
1980: J T Li; David W Scott
Role of self carriers in the immune response and tolerance. VI. Induction and reversal of TNP-modified self unresponsiveness in vitro.
Journal of immunology (Baltimore, Md. : 1950) 1980;125(6):2380-4.
1980: M L Cohn; David W Scott
Functional differentiation of T-cell precursors. II. Recovery of immunocompetence in lethally irradiated bone marrow reconstituted mice.
Thymus 1980;2(2):61-74.
1980: David W Scott; C Alexander
B-cell subsets responsive to fluorescein-conjugated antigens. II. "Cross-priming" and its elimination by bromodeoxyuridine and light.
Cellular immunology 1980;53(2):376-81.
1980: David W Scott
B-cell subsets responsive to fluorescein-conjugated antigens. I. Sensitivity to anti-IgD, tolerance, and cross-priming.
Cellular immunology 1980;53(2):365-75.
1980: R R Bollinger; David W Scott
Creation and properties of histocompatibility antigen-cell conjugates. II. Antibody tolerance after treatment with donor histocompatibility antigen chemically coupled to recipient spleen cells.
Transplantation 1980;29(6):449-53.
1980: R R Bollinger; David W Scott
Creation and properties of histocompatibility antigen-cell conjugates. I. Preparation and immunological properties of rat histocompatibility antigens.
Transplantation 1980;29(6):444-8.
1980: M Venkataraman; David W Scott
Cellular events in tolerance. VIII. Analysis of the proliferative capacity of antigen-binding cells isolated from normal or tolerant spleens.
Journal of immunology (Baltimore, Md. : 1950) 1980;124(2):607-10.
1980: David W Scott; C Long; J J Jandinski; J T Li
Role of self MHC carriers in tolerance and the immune response.
Immunological reviews 1980;50():275-309.
1980: J J Jandinski; J Li; P J Wettstein; Jeffrey Frelinger; David W Scott
Role of self carriers in the immune response and tolerance. V. Reversal of trinitrophenyl-modified self suppression of the B-cell response by blocking of H-2 antigens.
The Journal of experimental medicine 1980;151(1):133-43.
1979: J J Jandinski; David W Scott
Role of self carriers in the immune response and tolerance. IV. Active T cell suppression in the maintenance of B cell tolerance to a "T-independent" antigen.
Journal of immunology (Baltimore, Md. : 1950) 1979;123(6):2447-50.
1979: M Venkataraman; David W Scott
B-cell subsets responsive to fluorescein-conjugated antigens. III. Differential effect of E. Coli lipopolysaccharide on T-dependent and T-independent responses in vivo.
Immunology 1979;38(3):519-27.
1979: M L Cohn; David W Scott
Functional differentiation of T cell precursors. I. Parameters of carrier-specific tolerance in murine helper T cell precursors.
Journal of immunology (Baltimore, Md. : 1950) 1979;123(5):2083-7.
1979: M Venkataraman; David W Scott
Cellular events in tolerance. VII. Decrease in tolerant spleens of PFC precursors stimulated in vitro by specific antigen or mitogen.
Cellular immunology 1979;47(2):323-31.
1979: David W Scott; M Venkataraman; J J Jandinski
Multiple pathways of B lymphocyte tolerance.
Immunological reviews 1979;43():241-80.
1978: David W Scott
Role of self carriers in the immune response and tolerance. III. B cell tolerance induced by hapten-modified-self involves both active T cell-mediated suppression and direct blockade.
Cellular immunology 1978;37(2):327-35.
1978: J E Layton; G R Johnson; David W Scott; G J Nossal
The anti-delta suppressed mouse.
European journal of immunology 1978;8(5):325-30.
1978: David W Scott; J E Layton; G R Johnson
Surface immunoglobulin phenotype of murine spleen cells which form B cell colonies in agar.
European journal of immunology 1978;8(4):286-8.
1978: K H Singer; C Johnston; D B Amos; David W Scott
Selective depletion and enrichment of alloreactive cytolytic effector lymphocytes using anti-fluorescein affinity columns.
Cellular immunology 1978;36(1):75-85.
1978: David W Scott
Role of IgD in the immune response and tolerance. II. Precursor analysis of murine B cells separated on the basis of surface IgD or treated with an anti-delta serum.
European journal of immunology 1978;8(1):13-6.
1977: David W Scott; J E Layton; G J Nossal
Role of IgD in the immune response and tolerance. I. Anti-delta pretreatment facilitates tolerance induction in adult B cells in vitro.
The Journal of experimental medicine 1977;146(6):1473-83.
1977: M Venkataraman; David W Scott
Cellular events in tolerance. VI. Neonatal vs adult B cell tolerance: differences in antigen-binding cell patterns and lipopolysaccharide stimulation.
Journal of immunology (Baltimore, Md. : 1950) 1977;119(6):1879-81.
1977: M Venkataraman; M Aldo-Benson; Y Borel; David W Scott
Persistence of antigen-binding cells with surface tolerogen: isologous versus heterologous immunoglobulin carriers.
Journal of immunology (Baltimore, Md. : 1950) 1977;119(3):1006-9.
1977: Alfred P. Sanfilippo; David W Scott
The induction of carrier-specific helper cell tolerance in presensitized rats.
European journal of immunology 1977;7(5):283-7.
1977: A H Johnson; David W Scott; P T McKeown; P A Pool; D B Amos
Affinity chromatography with antifluorescein antibody to separate Ig-positive cells: preliminary report.
Transplantation proceedings 1977;9(1 Suppl 1):145-6.
1977: J W Moorhead; David W Scott
Tolerance and contact sensitivity to DNFB in mice. VII. Functional demonstration of cell-associated tolerogen in lymph node cell populations containing specific suppressor cells.
Cellular immunology 1977;28(2):443-8.
1977: Alfred P. Sanfilippo; David W Scott
Carrier-specific unresponsiveness in reaginic antibody formation. II. Suppression of hapten and carrier responsiveness in presensitized rats.
Cellular immunology 1977;28(2):435-42.
1977: Alfred P. Sanfilippo; David W Scott
Carrier-specific unresponsiveness in reaginic antibody formation. I. Induction of helper cell tolerance in rats.
Cellular immunology 1977;28(2):427-34.
1977: J W Goding; David W Scott; J E Layton
Genetics, cellular expression and function of IgD and IgM receptors.
Immunological reviews 1977;37():152-86.
1977: C A Long; David W Scott
Role of self-carriers in the immune response and tolerance. II. Parameters of tolerance induced by haptenated lymphoid cells.
European journal of immunology 1977;7(1):1-6.
1977: R R Bollinger; David W Scott
Induction of tolerance to solubilized rat histocompatibility antigens.
Surgical forum 1977;28():331-3.
1976: David W Scott; C A Long
Role of self-carriers in the immune response and tolerance. I. B-cell unresponsiveness and cytotoxic T-cell immunity induced by haptenated syngeneic lymphoid cells.
The Journal of experimental medicine 1976;144(5):1369-74.
1976: Alfred P. Sanfilippo; M L Cohn; David W Scott
Effect of carrier-specific tolerance on the generation of helper cell function.
European journal of immunology 1976;6(10):742-6.
1976: David W Scott
Antifluorescein affinity columns. Isolation and immunocompetence of lymphocytes that bind fluoresceinated antigens in vivo or in vitro.
The Journal of experimental medicine 1976;144(1):69-78.
1976: David W Scott; E Diener
Effect of lipopolysaccharide on the induction of tolerance to polymerized flagellin.
Journal of immunology (Baltimore, Md. : 1950) 1976;116(5):1220-3.
1976: David W Scott
Cellular events in tolerance. V. Detection, isolation and fate of lymphoid cells which bind fluoresccinated antigen in vivo.
Cellular immunology 1976;22(2):311-22.
1976: R R Bollinger; David W Scott
Isolation and biological characterization of rat histocompatibility antigens.
Surgical forum 1976;27(62):325-7.
1976: Alfred P. Sanfilippo; David W Scott
The effects of carrier-specific helper T-cell tolerance on antibody avidity in the anti-hapten response.
Cellular immunology 1976;21(1):112-20.
1975: David W Scott; S H Josephs
Uridine labeling of human lymphocytes: differential uptake by T and B cells.
Cellular immunology 1975;20(1):64-8.
1975: E A Greeley; David W Scott
Receptors for antigen on lymphoid cells. II. The nature of the molecule responsible for plaque-forming cell adherence.
Journal of immunology (Baltimore, Md. : 1950) 1975;115(2):409-13.
1975: A R Chauvenet; David W Scott
A lectin model for unresponsiveness. I. Reversible effects of high doses of concanavalin A on spontaneous and induced DNA synthesis.
Journal of immunology (Baltimore, Md. : 1950) 1975;114(1 Pt 2):470-5.
1974: E Greeley; G Berke; David W Scott
Receptors for antigen on lymphoid cells. I. Immunoadsorption of plaque-forming cells to poly-L-lysine-fixed antigen monolayers.
Journal of immunology (Baltimore, Md. : 1950) 1974;113(6):1883-90.
1974: Alfred P. Sanfilippo; David W Scott
Cellular events in tolerance. III. Carrier tolerance as a model for T cell unresponsiveness.
Journal of immunology (Baltimore, Md. : 1950) 1974;113(6):1661-7.
1974: J C Howard; David W Scott
The identification of sera distinguishing marrow-derived and thymus-derived lymphocytes in the rat thoracic duct.
Immunology 1974;27(5):903-22.
1974: E P Ornellas; Alfred P. Sanfilippo; David W Scott
Cellular events in tolerance. IV. The effect of a graft-versus-host reaction and endotoxin on hapten- and carrier-specific tolerance.
European journal of immunology 1974;4(9):587-91.
1974: David W Scott; R G McKenzie
Rat B cells: identity of immunoglobulin-bearing cells with a population of lightly uridine-labeled cells.
Cellular immunology 1974;12(1):61-5.
1974: David W Scott
Cellular events in tolerance. II. Similar specificity of carrier cross-tolerance in vivo and cross-stimulation in vitro.
Journal of immunology (Baltimore, Md. : 1950) 1974;112(4):1354-9.
1974: David W Scott; E P Ornellas
Allogeneic interactions in the immune response and tolerance. II. Mechanism of stimulation of TNP plaque forming cells in normal rats.
Cellular immunology 1974;11(1-3):116-21.
1974: E P Ornellas; David W Scott
Allogeneic interactions in the immune response and tolerance. I. The allogeneic effect in unprimed rats and mice.
Cellular immunology 1974;11(1-3):108-15.
1973: David W Scott
Cellular events in tolerance. I. Failure to demonstrate activation of lymphocytes, blocking factors, or suppressor cells during the induction of tolerance to a soluble protein.
Journal of immunology (Baltimore, Md. : 1950) 1973;111(3):789-96.
1972: N L Levy; David W Scott; R Snyderman
Bone marrow-derived lymphoid cells (B cells): functional depletion with cobra factor and fresh serum.
Science (New York, N.Y.) 1972;178(4063):866-7.
1972: J C Howard; David W Scott
The role of recirculating lymphocytes in the immunological competence of rat bone marrow cells.
Cellular immunology 1972;3(3):421-9.
1972: David W Scott; J C Howard
Collaboration between thymus-derived and marrow-derived thoracic duct lymphocytes in the hemolysin response of the rat.
Cellular immunology 1972;3(3):430-41.
1970: David W Scott; B H Waksman; S Bauminger; M Sela
Induction of tolerance to poly-DL-alanyl ribonuclease in adult rats.
Immunochemistry 1970;7(4):357-62.
1970: David W Scott; R K Gershon
Determination of total and merecaptothanol-resistant antibody in the same serum sample.
Clinical and experimental immunology 1970;6(2):313-6.
1969: David W Scott; B H Waksman
Mechanism of immunologic tolerance. I. Induction of tolerance to bovine gamma-globulin by injection of antigen into intact organs in vitro.
Journal of immunology (Baltimore, Md. : 1950) 1969;102(2):347-54.
1968: David W Scott; B H Waksman
Tolerance in vitro: suppression of immune responsiveness to bovine gamma-globulin after injection of antigen into intact lymphoid organs.
Journal of immunology (Baltimore, Md. : 1950) 1968;100(4):912-4.