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Martin Scott

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Claudia Bossen; Aubry Tardivel; Laure Willen; Carrie A Fletcher; M Perroud; Friedrich Beermann; Antonius G Rolink; Martin L Scott; Fabienne Mackay; Pascal Schneider
Mutation of the BAFF furin cleavage site impairs B-cell homeostasis and antibody responses.
Claudia Bossen; Teresa G Cachero; Aubry Tardivel; Karine Ingold; Laure Willen; Max Dobles; Martin L Scott; Aris Maquelin; Elodie Belnoue; Claire-Anne Siegrist; Stéphane Chevrier; Hans Acha-Orbea; Helen Leung; Fabienne Mackay; Jürg Tschopp; Pascal Schneider
TACI, unlike BAFF-R, is solely activated by oligomeric BAFF and APRIL to support survival of activated B cells and plasmablasts.
Lauri L Binné; Martin L Scott; Paul D Rennert
Human TIM-1 associates with the TCR complex and up-regulates T cell activation signals.

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All Publications

2011: Claudia Bossen; Aubry Tardivel; Laure Willen; Carrie A Fletcher; M Perroud; Friedrich Beermann; Antonius G Rolink; Martin L Scott; Fabienne Mackay; Pascal Schneider
Mutation of the BAFF furin cleavage site impairs B-cell homeostasis and antibody responses.
European journal of immunology 2011;41(3):787-97.
2008: Claudia Bossen; Teresa G Cachero; Aubry Tardivel; Karine Ingold; Laure Willen; Max Dobles; Martin L Scott; Aris Maquelin; Elodie Belnoue; Claire-Anne Siegrist; Stéphane Chevrier; Hans Acha-Orbea; Helen Leung; Fabienne Mackay; Jürg Tschopp; Pascal Schneider
TACI, unlike BAFF-R, is solely activated by oligomeric BAFF and APRIL to support survival of activated B cells and plasmablasts.
Blood 2008;111(3):1004-12.
2007: Lauri L Binné; Martin L Scott; Paul D Rennert
Human TIM-1 associates with the TCR complex and up-regulates T cell activation signals.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(7):4342-50.
2007: Irene Sizing; Véronique Bailly; Patricia McCoon; Wenjie Chang; Sambasiva Rao; Lourdes Pablo; Rachel Rennard; Meghan Walsh; Zhifang Li; Mohammad Zafari; Max Dobles; Leticia Tarilonte; Steven Miklasz; Gerard R Majeau; Kevin Godbout; Martin L Scott; Paul D Rennert
Epitope-dependent effect of anti-murine TIM-1 monoclonal antibodies on T cell activity and lung immune responses.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(4):2249-61.
2006: Mahasweta Girgenrath; Shawn Weng; Christine A Kostek; Beth Browning; Monica Wang; Sharron A N Brown; Jeffrey A Winkles; Jennifer S Michaelson; Normand E Allaire; Pascal Schneider; Martin L Scott; Yen-Ming Hsu; Hideo Yagita; Richard A Flavell; Jeffrey Boone Miller; Linda C Burkly; Timothy S Zheng
TWEAK, via its receptor Fn14, is a novel regulator of mesenchymal progenitor cells and skeletal muscle regeneration.
The EMBO journal 2006;25(24):5826-39.
2006: Chaim O Jacob; Luminita Pricop; Chaim Putterman; Michael N Koss; Yi Liu; Maria Kollaros; Sarah A Bixler; Christine Ambrose; Martin L Scott; William Stohl
Paucity of clinical disease despite serological autoimmunity and kidney pathology in lupus-prone New Zealand mixed 2328 mice deficient in BAFF.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(4):2671-80.
2005: Sha Mi; Robert H Miller; Xinhua Lee; Martin L Scott; Svetlane Shulag-Morskaya; Zhaohui Shao; Jufang Chang; Greg Thill; Melissa Levesque; Mingdi Zhang; Cathy Hession; Dinah W Y Sah; Bruce Trapp; Zhigang He; Vincent Jung; John McCoy; R Blake Pepinsky
LINGO-1 negatively regulates myelination by oligodendrocytes.
Nature neuroscience 2005;8(6):745-51.
2005: Zhaohui Shao; Jeffrey L Browning; Xinhua Lee; Martin L Scott; Svetlana Shulga-Morskaya; Normand E Allaire; Greg Thill; Melissa Levesque; Dinah W Y Sah; John McCoy; Beth Murray; Vincent Jung; R Blake Pepinsky; Sha Mi
TAJ/TROY, an orphan TNF receptor family member, binds Nogo-66 receptor 1 and regulates axonal regeneration.
Neuron 2005;45(3):353-9.
2004: Svetlana Shulga-Morskaya; Max Dobles; Meghan E Walsh; Lai Guan Ng; Fabienne Mackay; Sambasiva P Rao; Susan L Kalled; Martin L Scott
B cell-activating factor belonging to the TNF family acts through separate receptors to support B cell survival and T cell-independent antibody formation.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(4):2331-41.
2004: Lai Guan Ng; Andrew Sutherland; Rebecca Newton; Fang Qian; Teresa G Cachero; Martin L Scott; Jeffrey S Thompson; Julie Wheway; Tatyana Chtanova; Joanna Groom; Ian J Sutton; Cynthia Xin; Stuart G Tangye; Susan L Kalled; Fabienne Mackay; Charles R Mackay
B cell-activating factor belonging to the TNF family (BAFF)-R is the principal BAFF receptor facilitating BAFF costimulation of circulating T and B cells.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(2):807-17.
2004: Leonid Gorelik; Anne H Cutler; Greg Thill; Steven Miklasz; Dianna E Shea; Christine Ambrose; Sarah A Bixler; Lihe Su; Martin L Scott; Susan L Kalled
Cutting edge: BAFF regulates CD21/35 and CD23 expression independent of its B cell survival function.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(2):762-6.
2003: Leonid Gorelik; Kevin Gilbride; Max Dobles; Susan L Kalled; Daniel Zandman; Martin L Scott
Normal B cell homeostasis requires B cell activation factor production by radiation-resistant cells.
The Journal of experimental medicine 2003;198(6):937-45.
2003: Kalpit A Vora; Li Chun Wang; Sambasiva P Rao; Zhong-Ying Liu; Gerard R Majeau; Anne H Cutler; Paula S Hochman; Martin L Scott; Susan L Kalled
Cutting edge: germinal centers formed in the absence of B cell-activating factor belonging to the TNF family exhibit impaired maturation and function.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(2):547-51.
2003: Douglas A Rubinson; Christopher P Dillon; Adam V Kwiatkowski; Claudia Sievers; Lili Yang; Johnny Kopinja; Dina L Rooney; Mingdi Zhang; Melanie M Ihrig; Michael McManus; Frank B Gertler; Martin L Scott; Luk Van Parijs
A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference.
Nature genetics 2003;33(3):401-6.
2002: Joseph P Mizgerd; Martin L Scott; Matt R Spieker; Claire Doerschuk
Functions of IkappaB proteins in inflammatory responses to Escherichia coli LPS in mouse lungs.
American journal of respiratory cell and molecular biology 2002;27(5):575-82.
2001: Jeffrey S Thompson; Sarah A Bixler; Fang Qian; Kalpit A Vora; Martin L Scott; Teresa G Cachero; Cathy Hession; Pascal Schneider; Irene Sizing; Colleen Mullen; Kathy Strauch; Mohammad Zafari; Christopher D Benjamin; Jürg Tschopp; Jeffrey L Browning; Christine Ambrose
BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF.
Science (New York, N.Y.) 2001;293(5537):2108-11.
2001: B Schiemann; J L Gommerman; Kalpit A Vora; Teresa G Cachero; Svetlana Shulga-Morskaya; Max Dobles; Erica Frew; Martin L Scott
An essential role for BAFF in the normal development of B cells through a BCMA-independent pathway.
Science (New York, N.Y.) 2001;293(5537):2111-4.
2001: Bruce H Horwitz; Joseph P Mizgerd; Martin L Scott; Claire Doerschuk
Mechanisms of granulocytosis in the absence of CD18.
Blood 2001;97(6):1578-83.
2000: Max Dobles; Vasco Liberal; Martin L Scott; Robert Benezra; Peter K Sorger
Chromosome missegregation and apoptosis in mice lacking the mitotic checkpoint protein Mad2.
Cell 2000;101(6):635-45.
1999: Joseph P Mizgerd; Bruce H Horwitz; H C Quillen; Martin L Scott; Claire Doerschuk
Effects of CD18 deficiency on the emigration of murine neutrophils during pneumonia.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(2):995-9.
1999: Bruce H Horwitz; P Zelazowski; Yi Shen; Karen M Wolcott; Martin L Scott; David Baltimore; Clifford M Snapper
The p65 subunit of NF-kappa B is redundant with p50 during B cell proliferative responses, and is required for germline CH transcription and class switching to IgG3.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(4):1941-6.
1998: A J Koleske; A M Gifford; Martin L Scott; M Nee; Roderick T Bronson; Klaus Miczek; David Baltimore
Essential roles for the Abl and Arg tyrosine kinases in neurulation.
Neuron 1998;21(6):1259-72.
1997: Bruce H Horwitz; Martin L Scott; SR Cherry; Roderick T Bronson; David Baltimore
Failure of lymphopoiesis after adoptive transfer of NF-kappaB-deficient fetal liver cells.
Immunity 1997;6(6):765-72.
1996: Warren S Pear; Jon C Aster; Martin L Scott; Robert P Hasserjian; B Soffer; Jeffrey Sklar; David Baltimore
Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles.
The Journal of experimental medicine 1996;183(5):2283-91.
1995: Michael F Gurish; Warren S Pear; Richard L Stevens; Martin L Scott; K Sokol; N Ghildyal; M J Webster; X Hu; K Frank Austen; David Baltimore
Tissue-regulated differentiation and maturation of a v-abl-immortalized mast cell-committed progenitor.
Immunity 1995;3(2):175-86.
1993: Warren S Pear; G P Nolan; Martin L Scott; David Baltimore
Production of high-titer helper-free retroviruses by transient transfection.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(18):8392-6.
1993: T Fujita; G P Nolan; Hsiou-Chi Liou; Martin L Scott; David Baltimore
The candidate proto-oncogene bcl-3 encodes a transcriptional coactivator that activates through NF-kappa B p50 homodimers.
Genes & development 1993;7(7B):1354-63.
1993: Martin L Scott; T Fujita; Hsiou-Chi Liou; G P Nolan; David Baltimore
The p65 subunit of NF-kappa B regulates I kappa B by two distinct mechanisms.
Genes & development 1993;7(7A):1266-76.
1993: G P Nolan; T Fujita; K Bhatia; C Huppi; Hsiou-Chi Liou; Martin L Scott; David Baltimore
The bcl-3 proto-oncogene encodes a nuclear I kappa B-like molecule that preferentially interacts with NF-kappa B p50 and p52 in a phosphorylation-dependent manner.
Molecular and cellular biology 1993;13(6):3557-66.