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Roderick Scott

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Hesham Khairy; Gloria Adjei; Keith Allen-Redpath; Roderick H Scott
Actions of ethanolamine on cultured sensory neurones from neonatal rats.
Wael E Houssen; Zhibao Lu; RuAngelie Edrada-Ebel; Christina Chatzi; Steven J Tucker; Kristina Sepčić; Tom Turk; Ana Zovko; Sanbing Shen; Ines Mancini; Roderick H Scott; Marcel Jaspars
Chemical synthesis and biological activities of 3-alkyl pyridinium polymeric analogues of marine toxins.
Christina Chatzi; Roderick H Scott; Jin Pu; Bing Lang; Chizu Nakamoto; Colin D McCaig; Sanbing Shen
Derivation of homogeneous GABAergic neurons from mouse embryonic stem cells.

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2010: Hesham Khairy; Gloria Adjei; Keith Allen-Redpath; Roderick H Scott
Actions of ethanolamine on cultured sensory neurones from neonatal rats.
Neuroscience letters 2010;468(3):326-9.
2010: Wael E Houssen; Zhibao Lu; RuAngelie Edrada-Ebel; Christina Chatzi; Steven J Tucker; Kristina Sepčić; Tom Turk; Ana Zovko; Sanbing Shen; Ines Mancini; Roderick H Scott; Marcel Jaspars
Chemical synthesis and biological activities of 3-alkyl pyridinium polymeric analogues of marine toxins.
Journal of chemical biology 2010;3(3):113-25.
2009: Christina Chatzi; Roderick H Scott; Jin Pu; Bing Lang; Chizu Nakamoto; Colin D McCaig; Sanbing Shen
Derivation of homogeneous GABAergic neurons from mouse embryonic stem cells.
Experimental neurology 2009;217(2):407-16.
2009: Margit Winkler; Thomas Moraux; Hesham A Khairy; Roderick H Scott; Alexandra M Z Slawin; David O'Hagan
Synthesis and vanilloid receptor (TRPV1) activity of the enantiomers of alpha-fluorinated capsaicin.
Chembiochem : a European journal of chemical biology 2009;10(5):823-8.
2008: Kanola C David; Roderick H Scott; Graeme F Nixon
Advanced glycation endproducts induce a proliferative response in vascular smooth muscle cells via altered calcium signaling.
Biochemical pharmacology 2008;76(9):1110-20.
2008: Rhian M Evans; Kerrie N Wease; C J MacDonald; Hany A Khairy; Ruth A Ross; Roderick H Scott
Modulation of sensory neuron potassium conductances by anandamide indicates roles for metabolites.
British journal of pharmacology 2008;154(2):480-92.
2007: R M Evans; Roderick H Scott; Ruth A Ross
Chronic exposure of sensory neurones to increased levels of nerve growth factor modulates CB1/TRPV1 receptor crosstalk.
British journal of pharmacology 2007;152(3):404-13.
2007: Florence Folmer; Wael E Houssen; Roderick H Scott; Marcel Jaspars
Biomedical research tools from the seabed.
Current opinion in drug discovery & development 2007;10(2):145-52.
2007: David J Koss; Kathleen P Hindley; Kanola C David; Ines Mancini; Graziano Guella; Kristina Sepcić; Tom Turk; Katja Rebolj; Gernot Riedel; Bettina Platt; Roderick H Scott
A comparative study of the actions of alkylpyridinium salts from a marine sponge and related synthetic compounds in rat cultured hippocampal neurones.
BMC pharmacology 2007;7():1.
2006: Tarek A Temraz; Wael E Houssen; Marcel Jaspars; David R Woolley; Kerrie N Wease; Steven N Davies; Roderick H Scott
A pyridinium derivative from Red Sea soft corals inhibited voltage-activated potassium conductances and increased excitability of rat cultured sensory neurones.
BMC pharmacology 2006;6():10.
2006: Debra McLaggan; Noppadon Adjimatera; Kristina Sepcić; Marcel Jaspars; David J MacEwan; Ian S Blagbrough; Roderick H Scott
Pore forming polyalkylpyridinium salts from marine sponges versus synthetic lipofection systems: distinct tools for intracellular delivery of cDNA and siRNA.
BMC biotechnology 2006;6():6.
2006: Wael E Houssen; Marcel Jaspars; Kerrie N Wease; Roderick H Scott
Acute actions of marine toxin latrunculin A on the electrophysiological properties of cultured dorsal root ganglion neurones.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2006;142(1-2):19-29.
2006: James L Carr; Kerrie N Wease; Michael P Van Ryssen; Suzanne Paterson; Ben Agate; Katherine A Gallagher; C Tom A Brown; Roderick H Scott; Stuart Conway
In vitro photo-release of a TRPV1 agonist.
Bioorganic & medicinal chemistry letters 2006;16(1):208-12.
2004: David McClelland; Rhian M Evans; Louise Barkworth; Duncan J Martin; Roderick H Scott
A study comparing the actions of gabapentin and pregabalin on the electrophysiological properties of cultured DRG neurones from neonatal rats.
BMC pharmacology 2004;4():14.
2004: Rhian M Evans; Roderick H Scott; Ruth A Ross
Multiple actions of anandamide on neonatal rat cultured sensory neurones.
British journal of pharmacology 2004;141(7):1223-33.
2003: Frederic Coussin; Roderick H Scott; Graeme F Nixon
Sphingosine 1-phosphate induces CREB activation in rat cerebral artery via a protein kinase C-mediated inhibition of voltage-gated K+ channels.
Biochemical pharmacology 2003;66(9):1861-70.
2003: Steven J Tucker; David McClelland; Marcel Jaspars; Kristina Sepcić; David J MacEwan; Roderick H Scott
The influence of alkyl pyridinium sponge toxins on membrane properties, cytotoxicity, transfection and protein expression in mammalian cells.
Biochimica et biophysica acta 2003;1614(2):171-81.
2003: David McClelland; Rhian M Evans; I Abidin; S Sharma; F Z Choudhry; Marcel Jaspars; K Sepcić; Roderick H Scott
Irreversible and reversible pore formation by polymeric alkylpyridinium salts (poly-APS) from the sponge Reniera sarai.
British journal of pharmacology 2003;139(8):1399-408.
2003: J Pollock; JH Crawford; John F Wootton; John E T Corrie; Roderick H Scott
A comparison between the distinct inward currents activated in rat cultured dorsal root ganglion neurones by intracellular flash photolysis of two forms of caged cyclic guanosine monophosphate.
Neuroscience letters 2003;338(2):143-6.
2002: Frederic Coussin; Roderick H Scott; Alan Wise; Graeme F Nixon
Comparison of sphingosine 1-phosphate-induced intracellular signaling pathways in vascular smooth muscles: differential role in vasoconstriction.
Circulation research 2002;91(2):151-7.
2002: D J Martin; David McClelland; M B Herd; K G Sutton; Matthew D Hall; K Lee; RD Pinnock; Roderick H Scott
Gabapentin-mediated inhibition of voltage-activated Ca2+ channel currents in cultured sensory neurones is dependent on culture conditions and channel subunit expression.
Neuropharmacology 2002;42(3):353-66.
2002: K G Sutton; D J Martin; RD Pinnock; K Lee; Roderick H Scott
Gabapentin inhibits high-threshold calcium channel currents in cultured rat dorsal root ganglion neurones.
British journal of pharmacology 2002;135(1):257-65.
2002: J Pollock; Shona M McFarlane; Michelle C Connell; U Zehavi; Peter Vandenabeele; David J MacEwan; Roderick H Scott
TNF-alpha receptors simultaneously activate Ca2+ mobilisation and stress kinases in cultured sensory neurones.
Neuropharmacology 2002;42(1):93-106.
2001: D Kalikulov; A Ayar; F Nuritova; Bruno G Frenguelli; D McClelland; D J Martin; I Davidson; Roderick H Scott
Venom from Anemesia species of spider modulates high voltage-activated Ca(2+) currents from rat cultured sensory neurones and excitatory post synaptic currents from rat hippocampal slices.
Cell calcium 2001;30(3):212-21.
2001: Ruth A Ross; Angela A Coutts; Shona M McFarlane; Sharon Anavi-Goffer; Andrew J Irving; Roger G Pertwee; David J MacEwan; Roderick H Scott
Actions of cannabinoid receptor ligands on rat cultured sensory neurones: implications for antinociception.
Neuropharmacology 2001;40(2):221-32.
2000: Roderick H Scott; A D Whyment; A Foster; K H Gordon; B F Milne; Marcel Jaspars
Analysis of the structure and electrophysiological actions of halitoxins: 1,3 alkyl-pyridinium salts from Callyspongia ridleyi.
The Journal of membrane biology 2000;176(2):119-31.
2000: JH Crawford; Anna Wainwright; Robert P Heavens; J Pollock; D J Martin; Roderick H Scott; Guy R Seabrook
Mobilisation of intracellular Ca2+ by mGluR5 metabotropic glutamate receptor activation in neonatal rat cultured dorsal root ganglia neurones.
Neuropharmacology 2000;39(4):621-30.
2000: Roderick H Scott; J Pollock; A Ayar; NM Thatcher; U Zehavi
Synthesis and use of caged sphingolipids.
Methods in enzymology 2000;312():387-400.
1999: J Pollock; JH Crawford; John F Wootton; Guy R Seabrook; Roderick H Scott
Metabotropic glutamate receptor activation and intracellular cyclic ADP-ribose release Ca2+ from the same store in cultured DRG neurones.
Cell calcium 1999;26(3-4):139-48.
1999: A Ayar; C Storer; E L Tatham; Roderick H Scott
The effects of changing intracellular Ca2+ buffering on the excitability of cultured dorsal root ganglion neurones.
Neuroscience letters 1999;271(3):171-4.
1999: Roderick H Scott; K O'Brien; L Roberts; W Mordue; J Mordue Luntz
Extracellular and intracellular actions of azadirachtin on the electrophysiological properties of cultured rat DRG neurones.
Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology 1999;123(1):85-93.
1999: A Ayar; Roderick H Scott
The actions of ryanodine on Ca2+-activated conductances in rat cultured DRG neurones; evidence for Ca2+-induced Ca2+ release.
Naunyn-Schmiedeberg's archives of pharmacology 1999;359(2):81-91.
1998: Roderick H Scott; NM Thatcher; A Ayar; S J Mitchell; J Pollock; M T Gibson; Ian Duce; E Moya; Ian S Blagbrough
Extracellular or intracellular application of argiotoxin-636 has inhibitory actions on membrane excitability and voltage-activated currents in cultured rat sensory neurones.
Neuropharmacology 1998;37(12):1563-78.
1998: Roderick H Scott; M T Gibson
Inhibition of voltage-activated K+ currents in cultured sensory neurons by the polyamine spider toxin argiotoxin-636 may involve a polyamine transporter and an intracellular site of action.
Biochemical Society transactions 1998;26(4):614-20.
1998: Kathy G Sutton; S R Stapleton; Roderick H Scott
Inhibitory actions of synthesised polyamine spider toxins and their analogues on Ca2+-activated Cl- currents recorded from cultured DRG neurones from neonatal rats.
Neuroscience letters 1998;251(2):117-20.
1998: A Ayar; NM Thatcher; U Zehavi; D R Trentham; Roderick H Scott
Mobilization of intracellular calcium by intracellular flash photolysis of caged dihydrosphingosine in cultured neonatal rat sensory neurones.
Acta biochimica Polonica 1998;45(2):311-26.
1997: JH Crawford; John F Wootton; Guy R Seabrook; Roderick H Scott
Activation of Ca2+-dependent currents in dorsal root ganglion neurons by metabotropic glutamate receptors and cyclic ADP-ribose precursors.
Journal of neurophysiology 1997;77(5):2573-84.
1997: Roderick H Scott; V J Gorton; L Harding; D Patel; S Pacey; C Kellenberger; H Hietter; I Bermudez
Inhibition of neuronal high voltage-activated calcium channels by insect peptides: a comparison with the actions of omega-conotoxin GVIA.
Neuropharmacology 1997;36(2):195-208.
1996: A Griffin; T M Newman; Roderick H Scott
Electrophysiological and ultrastructural events evoked by methacholine and intracellular photolysis of caged compounds in cultured ovine trachea submucosal gland cells.
Experimental physiology 1996;81(1):27-43.
1995: Roderick H Scott; A J Woods; M J Lacey; D Fernando; JH Crawford; Paul L R Andrews
An electrophysiological investigation of the effects of cisplatin and the protective actions of dexamethasone on cultured dorsal root ganglion neurones from neonatal rats.
Naunyn-Schmiedeberg's archives of pharmacology 1995;352(3):247-55.
1995: Roderick H Scott; Kathy G Sutton; A Griffin; S R Stapleton; K P Currie
Aspects of calcium-activated chloride currents: a neuronal perspective.
Pharmacology & therapeutics 1995;66(3):535-65.
1995: H A Pearson; Kathy G Sutton; Roderick H Scott; Annette C Dolphin
Characterization of Ca2+ channel currents in cultured rat cerebellar granule neurones.
The Journal of physiology 1995;482 ( Pt 3)():493-509.
1995: K P Currie; John F Wootton; Roderick H Scott
Activation of Ca(2+)-dependent Cl- currents in cultured rat sensory neurones by flash photolysis of DM-nitrophen.
The Journal of physiology 1995;482 ( Pt 2)():291-307.
1995: S R Stapleton; B A Bell; John F Wootton; Roderick H Scott
Modulation of Ca(2+)-dependent currents in metabolically stressed cultured sensory neurones by intracellular photorelease of ATP.
British journal of pharmacology 1995;114(2):544-50.
1994: A Griffin; Roderick H Scott
Properties of K+ currents recorded from cultured ovine trachea submucosal gland cells.
Respiration physiology 1994;96(2-3):297-309.
1994: Roderick H Scott; M I Manikon; Paul L R Andrews
Actions of cisplatin on the electrophysiological properties of cultured dorsal root ganglion neurones from neonatal rats.
Naunyn-Schmiedeberg's archives of pharmacology 1994;349(3):287-94.
1994: S R Stapleton; Roderick H Scott; B A Bell
Effects of metabolic blockers on Ca(2+)-dependent currents in cultured sensory neurones from neonatal rats.
British journal of pharmacology 1994;111(1):57-64.
1993: H A Pearson; Kathy G Sutton; Roderick H Scott; Annette C Dolphin
Ca2+ currents in cerebellar granule neurones: role of internal Mg2+ in altering characteristics and antagonist effects.
Neuropharmacology 1993;32(11):1171-83.
1993: Annette C Dolphin; H A Pearson; A S Menon-Johansson; M I Sweeney; Kathy G Sutton; E Huston; G P Cullen; Roderick H Scott
G protein modulation of voltage-dependent calcium channels and transmitter release.
Biochemical Society transactions 1993;21(2):391-5.
1993: Roderick H Scott; Kathy G Sutton; Annette C Dolphin
Interactions of polyamines with neuronal ion channels.
Trends in neurosciences 1993;16(4):153-60.
1992: S R Stapleton; K P Currie; Roderick H Scott; B A Bell
Palmitoyl-DL-carnitine has calcium-dependent effects on cultured neurones from rat dorsal root ganglia.
British journal of pharmacology 1992;107(4):1192-7.
1992: K P Currie; K Swann; Antony Galione; Roderick H Scott
Activation of Ca(2+)-dependent currents in cultured rat dorsal root ganglion neurones by a sperm factor and cyclic ADP-ribose.
Molecular biology of the cell 1992;3(12):1415-25.
1992: K P Currie; Roderick H Scott
Calcium-activated currents in cultured neurones from rat dorsal root ganglia.
British journal of pharmacology 1992;106(3):593-602.
1992: Roderick H Scott; K P Currie; Kathy G Sutton; Annette C Dolphin
Modulation of neuronal Ca(2+)-dependent currents by neurotransmitters, G-proteins and toxins.
Biochemical Society transactions 1992;20(2):443-9.
1992: Roderick H Scott; M I Sweeney; E M Kobrinsky; H A Pearson; G H Timms; I A Pullar; S Wedley; Annette C Dolphin
Actions of arginine polyamine on voltage and ligand-activated whole cell currents recorded from cultured neurones.
British journal of pharmacology 1992;106(1):199-207.
1991: Annette C Dolphin; E Huston; H Pearson; A Menon-Johanssen; M I Sweeney; M E Adams; Roderick H Scott
G protein modulation of calcium entry and transmitter release.
Annals of the New York Academy of Sciences 1991;635():139-52.
1990: Roderick H Scott; Annette C Dolphin; V P Bindokas; M E Adams
Inhibition of neuronal Ca2+ channel currents by the funnel web spider toxin omega-Aga-IA.
Molecular pharmacology 1990;38(5):711-8.
1990: Roderick H Scott; Annette C Dolphin
Voltage-dependent modulation of rat sensory neurone calcium channel currents by G protein activation: effect of a dihydropyridine antagonist.
British journal of pharmacology 1990;99(4):629-30.
1990: Annette C Dolphin; Roderick H Scott
Activation of calcium channel currents in rat sensory neurons by large depolarizations: effect of Guanine nucleotides and (-)-baclofen.
The European journal of neuroscience 1990;2(1):104-8.
1990: Roderick H Scott; John F Wootton; Annette C Dolphin
Modulation of neuronal T-type calcium channel currents by photoactivation of intracellular guanosine 5'-O(3-thio) triphosphate.
Neuroscience 1990;38(2):285-94.
1990: E Huston; Roderick H Scott; Annette C Dolphin
A comparison of the effect of calcium channel ligands and GABAB agonists and antagonists on transmitter release and somatic calcium channel currents in cultured neurons.
Neuroscience 1990;38(3):721-9.
1990: Annette C Dolphin; E Huston; Roderick H Scott
Direct and indirect modulation of neuronal calcium currents by G-protein activation.
Biochemical Society symposium 1990;56():45-60.
1989: Annette C Dolphin; Roderick H Scott
Interaction between calcium channel ligands and guanine nucleotides in cultured rat sensory and sympathetic neurones.
The Journal of physiology 1989;413():271-88.
1989: Annette C Dolphin; S M McGuirk; Roderick H Scott
An investigation into the mechanisms of inhibition of calcium channel currents in cultured sensory neurones of the rat by guanine nucleotide analogues and (-)-baclofen.
British journal of pharmacology 1989;97(1):263-73.
1989: Annette C Dolphin; Roderick H Scott
Modulation of Ca2+-channel currents in sensory neurons by pertussis toxin-sensitive G-proteins.
Annals of the New York Academy of Sciences 1989;560():387-90.
1988: Roderick H Scott; S M McGuirk; Annette C Dolphin
Modulation of divalent cation-activated chloride ion currents.
British journal of pharmacology 1988;94(3):653-62.
1988: Roderick H Scott; Annette C Dolphin
The agonist effect of Bay K 8644 on neuronal calcium channel currents is promoted by G-protein activation.
Neuroscience letters 1988;89(2):170-5.
1988: Annette C Dolphin; John F Wootton; Roderick H Scott; David R Trentham
Photoactivation of intracellular guanosine triphosphate analogues reduces the amplitude and slows the kinetics of voltage-activated calcium channel currents in sensory neurones.
Pflügers Archiv : European journal of physiology 1988;411(6):628-36.
1987: Roderick H Scott; Annette C Dolphin
Activation of a G protein promotes agonist responses to calcium channel ligands.
Nature 1987;330(6150):760-2.
1987: Annette C Dolphin; Roderick H Scott
Calcium channel currents and their inhibition by (-)-baclofen in rat sensory neurones: modulation by guanine nucleotides.
The Journal of physiology 1987;386():1-17.
1987: Roderick H Scott; I R Duce
Pharmacology of GABA receptors on skeletal muscle fibres of the locust (Schistocerca gregaria).
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology 1987;86(2):305-11.
1986: Roderick H Scott; I R Duce
Anion selectivity of gamma-aminobutyric acid (GABA) 22,23-dihydroavermectin B1a (DHAVM)-induced conductance changes on locust muscle.
Neuroscience letters 1986;68(2):197-201.
1985: I R Duce; Roderick H Scott
Actions of dihydroavermectin B1a on insect muscle.
British journal of pharmacology 1985;85(2):395-401.