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Walter Scott

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TOP 3
Antonio J Acosta-Hoyos; Suzanne E Matsuura; Peter R Meyer; Walter A Scott
A role of template cleavage in reduced excision of chain-terminating nucleotides by human immunodeficiency virus type 1 reverse transcriptase containing the M184V mutation.
Walter A Scott
Structures of reverse transcriptase pre- and post-excision complexes shed new light on HIV-1 AZT resistance.
Wiriya Rutvisuttinunt; Peter R Meyer; Walter A Scott
Interactions between HIV-1 reverse transcriptase and the downstream template strand in stable complexes with primer-template.

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All Publications

2012: Antonio J Acosta-Hoyos; Suzanne E Matsuura; Peter R Meyer; Walter A Scott
A role of template cleavage in reduced excision of chain-terminating nucleotides by human immunodeficiency virus type 1 reverse transcriptase containing the M184V mutation.
Journal of virology 2012;86(9):5122-33.
2011: Walter A Scott
Structures of reverse transcriptase pre- and post-excision complexes shed new light on HIV-1 AZT resistance.
Viruses 2011;3(1):20-5.
2008: Wiriya Rutvisuttinunt; Peter R Meyer; Walter A Scott
Interactions between HIV-1 reverse transcriptase and the downstream template strand in stable complexes with primer-template.
PloS one 2008;3(10):e3561.
2007: Peter R Meyer; Wiriya Rutvisuttinunt; Suzanne E Matsuura; Antero G So; Walter A Scott
Stable complexes formed by HIV-1 reverse transcriptase at distinct positions on the primer-template controlled by binding deoxynucleoside triphosphates or foscarnet.
Journal of molecular biology 2007;369(1):41-54.
2006: Peter R Meyer; Anthony J Smith; Suzanne E Matsuura; Walter A Scott
Chain-terminating dinucleoside tetraphosphates are substrates for DNA polymerization by human immunodeficiency virus type 1 reverse transcriptase with increased activity against thymidine analogue-resistant mutants.
Antimicrobial agents and chemotherapy 2006;50(11):3607-14.
2006: Anthony James Smith; Walter A Scott
The influence of natural substrates and inhibitors on the nucleotide-dependent excision activity of HIV-1 reverse transcriptase in the infected cell.
Current pharmaceutical design 2006;12(15):1827-41.
2005: Anthony J Smith; Peter R Meyer; Deshratn Asthana; Margarita R Ashman; Walter A Scott
Intracellular substrates for the primer-unblocking reaction by human immunodeficiency virus type 1 reverse transcriptase: detection and quantitation in extracts from quiescent- and activated-lymphocyte subpopulations.
Antimicrobial agents and chemotherapy 2005;49(5):1761-9.
2004: Eric Lorenzo; Maria C Colon; Sharilyn Almodovar; Irvin M Maldonado; Sandra Gonzalez; Sonia E Costa; Martin D Hill; Rafael Mendoza; Gladys Sepulveda; Richard Yanagihara; Vivek R Nerurkar; Rakesh Kumar; Yasuhiro Yamamura; Walter A Scott; Anil Kumar
Influence of CD4+ T cell counts on viral evolution in HIV-infected individuals undergoing suppressive HAART.
Virology 2004;330(1):116-26.
2004: Peter R Meyer; Anthony J Smith; Suzanne E Matsuura; Walter A Scott
Effects of primer-template sequence on ATP-dependent removal of chain-terminating nucleotide analogues by HIV-1 reverse transcriptase.
The Journal of biological chemistry 2004;279(44):45389-98.
2003: Peter R Meyer; Suzanne E Matsuura; Dianna Zonarich; Rahul R Chopra; Eric Pendarvis; Holly Bazmi; John W Mellors; Walter A Scott
Relationship between 3'-azido-3'-deoxythymidine resistance and primer unblocking activity in foscarnet-resistant mutants of human immunodeficiency virus type 1 reverse transcriptase.
Journal of virology 2003;77(11):6127-37.
2003: Krithika Subramanian; Wiriya Rutvisuttinunt; Walter A Scott; Richard S Myers
The enzymatic basis of processivity in lambda exonuclease.
Nucleic acids research 2003;31(6):1585-96.
2003: Peter R Meyer; Johan Lennerstrand; Suzanne E Matsuura; Brendan Larder; Walter A Scott
Effects of dipeptide insertions between codons 69 and 70 of human immunodeficiency virus type 1 reverse transcriptase on primer unblocking, deoxynucleoside triphosphate inhibition, and DNA chain elongation.
Journal of virology 2003;77(6):3871-7.
2002: Peter R Meyer; Suzanne E Matsuura; Adviye A Tolun; Ingrid Pfeifer; Antero G So; John W Mellors; Walter A Scott
Effects of specific zidovudine resistance mutations and substrate structure on nucleotide-dependent primer unblocking by human immunodeficiency virus type 1 reverse transcriptase.
Antimicrobial agents and chemotherapy 2002;46(5):1540-5.
2000: Peter R Meyer; Suzanne E Matsuura; Ray F Schinazi; Antero G So; Walter A Scott
Differential removal of thymidine nucleotide analogues from blocked DNA chains by human immunodeficiency virus reverse transcriptase in the presence of physiological concentrations of 2'-deoxynucleoside triphosphates.
Antimicrobial agents and chemotherapy 2000;44(12):3465-72.
1999: Peter R Meyer; Suzanne E Matsuura; Abdul M Mian; Antero G So; Walter A Scott
A mechanism of AZT resistance: an increase in nucleotide-dependent primer unblocking by mutant HIV-1 reverse transcriptase.
Molecular cell 1999;4(1):35-43.
1998: Peter R Meyer; Suzanne E Matsuura; Antero G So; Walter A Scott
Unblocking of chain-terminated primer by HIV-1 reverse transcriptase through a nucleotide-dependent mechanism.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(23):13471-6.
1998: Susan A Fiscus; Michael D Hughes; Janet L Lathey; T Pi; J Brooks Jackson; Suraiya Rasheed; T Elbeik; R Reichman; AJ Japour; R Byington; Walter A Scott; B P Griffith; David A Katzenstein; Scott M Hammer
Changes in virologic markers as predictors of CD4 cell decline and progression of disease in human immunodeficiency virus type 1-infected adults treated with nucleosides. AIDS Clinical Trials Group Protocol 175 Team.
The Journal of infectious diseases 1998;177(3):625-33.
1998: Janet L Lathey; Michael D Hughes; Susan A Fiscus; T Pi; J Brooks Jackson; Suraiya Rasheed; T Elbeik; R Reichman; AJ Japour; Richard T D'Aquila; Walter A Scott; B P Griffith; Scott M Hammer; David A Katzenstein
Variability and prognostic values of virologic and CD4 cell measures in human immunodeficiency virus type 1-infected patients with 200-500 CD4 cells/mm(3) (ACTG 175). AIDS Clinical Trials Group Protocol 175 Team.
The Journal of infectious diseases 1998;177(3):617-24.
1997: Michael D Hughes; Victoria A Johnson; Martin S Hirsch; J W Bremer; T Elbeik; Alejo Erice; Daniel R Kuritzkes; Walter A Scott; Stephen A Spector; Nesli Basgoz; Margaret A Fischl; Richard T D'Aquila
Monitoring plasma HIV-1 RNA levels in addition to CD4+ lymphocyte count improves assessment of antiretroviral therapeutic response. ACTG 241 Protocol Virology Substudy Team.
Annals of internal medicine 1997;126(12):929-38.
1997: W Tong; C D Lu; S K Sharma; Suzanne E Matsuura; Antero G So; Walter A Scott
Nucleotide-induced stable complex formation by HIV-1 reverse transcriptase.
Biochemistry 1997;36(19):5749-57.
1996: A Unal; Eric Lorenzo; M Brown; Lesley Smith; Suzanne E Matsuura; Gwendolyn B Scott; Walter A Scott
Reverse transcriptase mutations in HIV-1-infected children treated with zidovudine.
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1996;13(2):140-5.
1996: Walter A Scott; Donald J Brambilla; Edward B Siwak; C Beatty; James Bremer; Robert W Coombs; Homayoon Farzadegan; Susan A Fiscus; S M Hammer; F Blaine Hollinger; N Khan; Suraiya Rasheed; Patricia Reichelderfer
Evaluation of an infectivity standard for real-time quality control of human immunodeficiency virus type 1 quantitative micrococulture assays. Participating Laboratories of The AIDS Clinical Trials Group.
Journal of clinical microbiology 1996;34(9):2312-5.
1996: Cecelia Hutto; Y Zhou; J He; Rebeca Benzaquen Geffin; M Hill; Walter A Scott; C Wood
Longitudinal studies of viral sequence, viral phenotype, and immunologic parameters of human immunodeficiency virus type 1 infection in perinatally infected twins with discordant disease courses.
Journal of virology 1996;70(6):3589-98.
1994: Dan Duiculescu; Rebeca Benzaquen Geffin; Gwendolyn B Scott; Walter A Scott
Clinical and immunological correlates of immune-complex-dissociated HIV-1 p24 antigen in HIV-1-infected children.
Journal of acquired immune deficiency syndromes 1994;7(8):807-15.
1994: X Zhan; C K Tan; Walter A Scott; Abdul M Mian; K M Downey; Antero G So
Catalytically distinct conformations of the ribonuclease H of HIV-1 reverse transcriptase by substrate cleavage patterns and inhibition by azidothymidylate and N-ethylmaleimide.
Biochemistry 1994;33(6):1366-72.
1992: Rebeca Benzaquen Geffin; Shenghan Lai; Cecelia Hutto; Gwendolyn B Scott; Walter A Scott; M Master; Wade P Parks
Quantitative analysis of human immunodeficiency virus type 1 antibody reactivity by western immunoblots: evaluation of relative antibody levels in seropositive individuals and mothers.
The Journal of infectious diseases 1992;165(1):111-8.
1989: M Wang; Walter A Scott; K R Rao; J Udey; Gregory Conner; Keith Brew
Recombinant bovine alpha-lactalbumin obtained by limited proteolysis of a fusion protein expressed at high levels in Escherichia coli.
The Journal of biological chemistry 1989;264(35):21116-21.
1989: L M Babé; Keith Brew; S E Matsuura; Walter A Scott
Epitopes on the major capsid protein of simian virus 40.
The Journal of biological chemistry 1989;264(5):2665-71.
1988: Paul C Schiller; J Amin; J Ananthan; M E Brown; Walter A Scott; Richard Voellmy
Cis-acting elements involved in the regulated expression of a human HSP70 gene.
Journal of molecular biology 1988;203(1):97-105.
1988: M E Brown; J Amin; Paul C Schiller; Richard Voellmy; Walter A Scott
Determinants for the DNase I-hypersensitive chromatin structure 5' to a human HSP70 gene.
Journal of molecular biology 1988;203(1):107-17.
1985: R D Gerard; B A Montelone; C F Walter; Jeffrey W Innis; Walter A Scott
Role of specific simian virus 40 sequences in the nuclease-sensitive structure in viral chromatin.
Molecular and cellular biology 1985;5(1):52-8.
1984: Jeffrey W Innis; Walter A Scott
DNA replication and chromatin structure of simian virus 40 insertion mutants.
Molecular and cellular biology 1984;4(8):1499-507.
1983: Jeffrey W Innis; Walter A Scott
Chromatin structure of simian virus 40-pBR322 recombinant plasmids in COS-1 cells.
Molecular and cellular biology 1983;3(12):2203-10.
1982: R D Gerard; M Woodworth-Gutai; Walter A Scott
Deletion mutants which affect the nuclease-sensitive site in simian virus 40 chromatin.
Molecular and cellular biology 1982;2(7):782-8.
1980: D J Wigmore; R W Eaton; Walter A Scott
Endonuclease-sensitive regions in SV40 chromatin from cells infected with duplicated mutants.
Virology 1980;104(2):462-73.