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Tom Sculley

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Human Herpesvirus 4

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Paul K Lovelock; Ee Ming Wong; Carl Sprung; Anna Marsh; Karen Hobson; Juliet D French; Melissa C Southey; Tom Sculley; Nirmala Pandeya; Melissa A Brown; Georgia Chenevix-Trench; Amanda B Spurdle; Michael McKay
Prediction of BRCA1 and BRCA2 mutation status using post-irradiation assays of lymphoblastoid cell lines is compromised by inter-cell-line phenotypic variability.
Wayne A Schroder; Marion Buck; Nicole Cloonan; John F Hancock; Andreas Suhrbier; Tom Sculley; Gillian Bushell
Human Sin1 contains Ras-binding and pleckstrin homology domains and suppresses Ras signalling.
Marion Buck; Andrew Burgess; Roslynn Stirzaker; Kenia G Krauer; Tom Sculley
Epstein-Barr virus nuclear antigen 3A contains six nuclear-localization signals.

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All Publications

2007: Paul K Lovelock; Ee Ming Wong; Carl Sprung; Anna Marsh; Karen Hobson; Juliet D French; Melissa C Southey; Tom Sculley; Nirmala Pandeya; Melissa A Brown; Georgia Chenevix-Trench; Amanda B Spurdle; Michael McKay
Prediction of BRCA1 and BRCA2 mutation status using post-irradiation assays of lymphoblastoid cell lines is compromised by inter-cell-line phenotypic variability.
Breast cancer research and treatment 2007;104(3):257-66.
2007: Wayne A Schroder; Marion Buck; Nicole Cloonan; John F Hancock; Andreas Suhrbier; Tom Sculley; Gillian Bushell
Human Sin1 contains Ras-binding and pleckstrin homology domains and suppresses Ras signalling.
Cellular signalling 2007;19(6):1279-89.
2006: Marion Buck; Andrew Burgess; Roslynn Stirzaker; Kenia G Krauer; Tom Sculley
Epstein-Barr virus nuclear antigen 3A contains six nuclear-localization signals.
The Journal of general virology 2006;87(Pt 10):2879-84.
2006: Maria A Frias; Carson C Thoreen; Jacob D Jaffe; Wayne A Schroder; Tom Sculley; Steven A Carr; David M Sabatini
mSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s.
Current biology : CB 2006;16(18):1865-70.
2006: Andrew Burgess; Marion Buck; Kenia G Krauer; Tom Sculley
Nuclear localization of the Epstein-Barr virus EBNA3B protein.
The Journal of general virology 2006;87(Pt 4):789-93.
2005: Wayne A Schroder; Gillian Bushell; Tom Sculley
The human stress-activated protein kinase-interacting 1 gene encodes JNK-binding proteins.
Cellular signalling 2005;17(6):761-7.
2004: Wayne A Schroder; Nicole Cloonan; Gillian Bushell; Tom Sculley
Alternative polyadenylation and splicing of mRNAs transcribed from the human Sin1 gene.
Gene 2004;339():17-23.
2004: Kenia G Krauer; Andrew Burgess; Marion Buck; James Flanagan; Tom Sculley; Brian Gabrielli
The EBNA-3 gene family proteins disrupt the G2/M checkpoint.
Oncogene 2004;23(7):1342-53.
2004: A Blood; C J Edwards; H H Ishii; Betty Pat; G Bryson; Tom Sculley; Glenda Gobe
Epstein-Barr virus-mediated protection against etoposide-induced apoptosis in BJA-B B cell lymphoma cells: role of Bcl-2 and caspase proteins.
Archives of virology 2004;149(2):289-302.
2004: Kenia G Krauer; Marion Buck; Deanna K Belzer; James Flanagan; Grace M Chojnowski; Tom Sculley
The Epstein-Barr virus nuclear antigen-6 protein co-localizes with EBNA-3 and survival of motor neurons protein.
Virology 2004;318(1):280-94.
2004: Kenia G Krauer; Marion Buck; James Flanagan; Deanna K Belzer; Tom Sculley
Identification of the nuclear localization signals within the Epstein-Barr virus EBNA-6 protein.
The Journal of general virology 2004;85(Pt 1):165-72.
2003: James Flanagan; Jaap Middeldorp; Tom Sculley
Localization of the Epstein-Barr virus protein LMP 1 to exosomes.
The Journal of general virology 2003;84(Pt 7):1871-9.
2002: Wayne A Schroder; Norbert Kienzle; Gillian Bushell; Tom Sculley
Antiserum raised against the Epstein-Barr virus BARF0 protein reacts to HLA-DR beta chain.
Archives of virology 2002;147(4):723-9.
2002: Tom Sculley; Marion Buck; Brian Gabrielli; Peter G Parsons; Kenia G Krauer
A histone deacetylase inhibitor, azelaic bishydroxamic acid, shows cytotoxicity on Epstein-Barr virus transformed B-cell lines: a potential therapy for posttransplant lymphoproliferative disease.
Transplantation 2002;73(2):271-9.
1999: Kenia G Krauer; Marion Buck; Tom Sculley
Characterization of the transcriptional repressor RBP in Epstein-Barr virus-transformed B cells.
The Journal of general virology 1999;80 ( Pt 12)():3217-26.
1999: Norbert Kienzle; Marion Buck; S Greco; Kenia G Krauer; Tom Sculley
Epstein-Barr virus-encoded RK-BARF0 protein expression.
Journal of virology 1999;73(10):8902-6.
1999: Norbert Kienzle; Tom Sculley; S Greco; Rajiv Khanna
Cutting edge: silencing virus-specific cytotoxic T cell-mediated immune recognition by differential splicing: a novel implication of RNA processing for antigen presentation.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(12):6963-6.
1999: Marion Buck; S Cross; Kenia G Krauer; Norbert Kienzle; Tom Sculley
A-type and B-type Epstein-Barr virus differ in their ability to spontaneously enter the lytic cycle.
The Journal of general virology 1999;80 ( Pt 2)():441-5.
1999: Norbert Kienzle; DB Young; D Liaskou; Marion Buck; S Greco; Tom Sculley
Intron retention may regulate expression of Epstein-Barr virus nuclear antigen 3 family genes.
Journal of virology 1999;73(2):1195-204.
1998: Kenia G Krauer; Deanna K Belzer; D Liaskou; Marion Buck; S Cross; T Honjo; Tom Sculley
Regulation of interleukin-1beta transcription by Epstein-Barr virus involves a number of latent proteins via their interaction with RBP.
Virology 1998;252(2):418-30.
1998: Norbert Kienzle; Tom Sculley; L Poulsen; Marion Buck; S Cross; Nancy Raab-Traub; Rajiv Khanna
Identification of a cytotoxic T-lymphocyte response to the novel BARF0 protein of Epstein-Barr virus: a critical role for antigen expression.
Journal of virology 1998;72(8):6614-20.
1997: DB Young; Kenia G Krauer; Norbert Kienzle; Tom Sculley
Both A type and B type Epstein-Barr virus nuclear antigen 6 interact with RBP-2N.
The Journal of general virology 1997;78 ( Pt 7)():1671-4.
1997: Norbert Kienzle; S Cross; DB Young; Ihor Misko; Tom Sculley; C S Abrams
Evidence that the expression and phosphorylation status of pleckstrin is modulated by Epstein-Barr virus in human B lymphocytes.
Blood 1997;89(9):3488-90.
1997: K L Fries; Tom Sculley; Jennifer Webster-Cyriaque; P Rajadurai; R H Sadler; Nancy Raab-Traub
Identification of a novel protein encoded by the BamHI A region of the Epstein-Barr virus.
Journal of virology 1997;71(4):2765-71.
1996: Kenia G Krauer; Norbert Kienzle; D B Young; Tom Sculley
Epstein-Barr nuclear antigen-3 and -4 interact with RBP-2N, a major isoform of RBP-J kappa in B lymphocytes.
Virology 1996;226(2):346-53.
1996: B M Kerr; Norbert Kienzle; Jacqueline M Burrows; S Cross; Sharon L Silins; Marion Buck; E M Benson; B Coupar; Denis Moss; Tom Sculley
Identification of type B-specific and cross-reactive cytotoxic T-lymphocyte responses to Epstein-Barr virus.
Journal of virology 1996;70(12):8858-64.
1996: Norbert Kienzle; D Young; Sharon L Silins; Tom Sculley
Induction of pleckstrin by the Epstein-Barr virus nuclear antigen 3 family.
Virology 1996;224(1):167-74.
1996: Jacqueline M Burrows; Rajiv Khanna; Tom Sculley; M P Alpers; Denis Moss; Scott R Burrows
Identification of a naturally occurring recombinant Epstein-Barr virus isolate from New Guinea that encodes both type 1 and type 2 nuclear antigen sequences.
Journal of virology 1996;70(7):4829-33.
1996: Norbert Kienzle; D Young; S Zehntner; G Bushell; Tom Sculley
DNaseI treatment is a prerequisite for the amplification of cDNA from episomal-based genes.
BioTechniques 1996;20(4):612-6.
1996: Jacqueline M Burrows; Scott R Burrows; L M Poulsen; Tom Sculley; Denis Moss; Rajiv Khanna
Unusually high frequency of Epstein-Barr virus genetic variants in Papua New Guinea that can escape cytotoxic T-cell recognition: implications for virus evolution.
Journal of virology 1996;70(4):2490-6.
1995: Sharon L Silins; Tom Sculley
Burkitt's lymphoma cells are resistant to programmed cell death in the presence of the Epstein-Barr virus latent antigen EBNA-4.
International journal of cancer. Journal international du cancer 1995;60(1):65-72.
1994: V P Argaet; Christopher W Schmidt; Scott R Burrows; Sharon L Silins; Michael Kurilla; D L Doolan; Andreas Suhrbier; Denis Moss; Elliott Kieff; Tom Sculley; Ihor Misko
Dominant selection of an invariant T cell antigen receptor in response to persistent infection by Epstein-Barr virus.
The Journal of experimental medicine 1994;180(6):2335-40.
1994: A Apolloni; Tom Sculley
Detection of A-type and B-type Epstein-Barr virus in throat washings and lymphocytes.
Virology 1994;202(2):978-81.
1994: Sharon L Silins; Tom Sculley
Modulation of vimentin, the CD40 activation antigen and Burkitt's lymphoma antigen (CD77) by the Epstein-Barr virus nuclear antigen EBNA-4.
Virology 1994;202(1):16-24.
1994: M T Kyaw-Tanner; D Esmore; Scott R Burrows; E M Benson; Tom Sculley
Epstein-Barr virus-specific cytotoxic T cell response in cardiac transplant recipients.
Transplantation 1994;57(11):1611-7.
1994: C Aitken; S K Sengupta; C Aedes; Denis Moss; Tom Sculley
Heterogeneity within the Epstein-Barr virus nuclear antigen 2 gene in different strains of Epstein-Barr virus.
The Journal of general virology 1994;75 ( Pt 1)():95-100.
1993: Rajiv Khanna; Scott R Burrows; Andreas Suhrbier; C A Jacob; H Griffin; Ihor Misko; Tom Sculley; Martin Rowe; A B Rickinson; Denis Moss
EBV peptide epitope sensitization restores human cytotoxic T cell recognition of Burkitt's lymphoma cells. Evidence for a critical role for ICAM-2.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(11):5154-62.
1993: M J Boyle; Tom Sculley; R Penny; William A Sewell; M Tschuchnigg; M F Berger; David A Cooper
The role of Epstein-Barr virus subtypes in human immunodeficiency virus-associated lymphoma.
Leukemia & lymphoma 1993;10(1-2):17-23.
1993: M J Boyle; E Vasak; M Tschuchnigg; J J Turner; Tom Sculley; R Penny; David A Cooper; B Tindall; William A Sewell
Subtypes of Epstein-Barr virus (EBV) in Hodgkin's disease: association between B-type EBV and immunocompromise.
Blood 1993;81(2):468-74.
1992: M T Kyaw; L Hurren; L Evans; D J Moss; David A Cooper; E Benson; D Esmore; Tom Sculley
Expression of B-type Epstein-Barr virus in HIV-infected patients and cardiac transplant recipients.
AIDS research and human retroviruses 1992;8(11):1869-74.
1992: Rajiv Khanna; Scott R Burrows; Michael Kurilla; C A Jacob; Ihor Misko; Tom Sculley; Elliott Kieff; Denis Moss
Localization of Epstein-Barr virus cytotoxic T cell epitopes using recombinant vaccinia: implications for vaccine development.
The Journal of experimental medicine 1992;176(1):169-76.
1992: Sharon L Silins; V P Argaet; Tom Sculley
Isolation of Epstein-Barr virus genomes using pulse-field gel electrophoresis.
Nucleic acids research 1992;20(11):2901.
1992: Denis Moss; Scott R Burrows; Rajiv Khanna; Ihor Misko; Tom Sculley
Immune surveillance against Epstein-Barr virus.
Seminars in immunology 1992;4(2):97-104.
1992: M J Boyle; Tom Sculley; David A Cooper; J J Turner; R Penny; William A Sewell
Epstein-Barr virus and HIV play no direct role in persistent generalized lymphadenopathy syndrome.
Clinical and experimental immunology 1992;87(3):357-61.
1992: Ihor Misko; C Schmidt; Margo Honeyman; T D Soszynski; Tom Sculley; Scott R Burrows; Denis Moss; K Burman
Failure of Epstein-Barr virus-specific cytotoxic T lymphocytes to lyse B cells transformed with the B95-8 strain is mapped to an epitope that associates with the HLA-B8 antigen.
Clinical and experimental immunology 1992;87(1):65-70.
1992: A Apolloni; D Moss; R Stumm; S Burrows; A Suhrbier; Ihor Misko; C Schmidt; Tom Sculley
Sequence variation of cytotoxic T cell epitopes in different isolates of Epstein-Barr virus.
European journal of immunology 1992;22(1):183-9.
1991: M J Boyle; William A Sewell; Tom Sculley; A Apolloni; J J Turner; C E Swanson; R Penny; David A Cooper
Subtypes of Epstein-Barr virus in human immunodeficiency virus-associated non-Hodgkin lymphoma.
Blood 1991;78(11):3004-11.
1991: Rajiv Khanna; C A Jacob; Scott R Burrows; Michael Kurilla; Elliott Kieff; Ihor Misko; Tom Sculley; Denis Moss
Expression of Epstein-Barr virus nuclear antigens in anti-IgM-stimulated B cells following recombinant vaccinia infection and their recognition by human cytotoxic T cells.
Immunology 1991;74(3):504-10.
1991: C Schmidt; Scott R Burrows; Tom Sculley; Denis Moss; Ihor Misko
Nonresponsiveness to an immunodominant Epstein-Barr virus-encoded cytotoxic T-lymphocyte epitope in nuclear antigen 3A: implications for vaccine strategies.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(21):9478-82.
1991: C Schmidt; Scott R Burrows; Denis Moss; Tom Sculley; Ihor Misko
Oligopeptide induction of a secondary cytotoxic T-cell response to Epstein-Barr virus in vitro.
Scandinavian journal of immunology 1991;33(4):411-20.
1991: Ihor Misko; Tom Sculley; C Schmidt; Denis Moss; T Soszynski; K Burman
Composite response of naive T cells to stimulation with the autologous lymphoblastoid cell line is mediated by CD4 cytotoxic T cell clones and includes an Epstein-Barr virus-specific component.
Cellular immunology 1991;132(2):295-307.
1991: Ihor Misko; C Schmidt; Denis Moss; Scott R Burrows; Tom Sculley
Cytotoxic T lymphocyte discrimination between type A Epstein-Barr virus transformants is mapped to an immunodominant epitope in EBNA 3.
The Journal of general virology 1991;72 ( Pt 2)():405-9.
1991: S J Robbins; J H Pope; Tom Sculley
Western blot analysis of antibody specificities in subacute sclerosing panencephalitis: reactivity to measles virus proteins produced in persistently infected cells.
Intervirology 1991;32(1):52-8.
1991: Denis Moss; Ihor Misko; Tom Sculley; A Apolloni; Rajiv Khanna; Scott R Burrows
Immune regulation of Epstein-Barr virus (EBV): EBV nuclear antigen as a target for EBV-specific T cell lysis.
Springer seminars in immunopathology 1991;13(2):147-56.
1990: Ihor Misko; C Schmidt; N Martin; Denis Moss; Tom Sculley; S Burrows; K J Burman
Lymphokine-activated killer (LAK) cells discriminate between Epstein-Barr virus (EBV)-positive Burkitt's lymphoma cells.
International journal of cancer. Journal international du cancer 1990;46(3):399-404.
1990: Tom Sculley; A Apolloni; L Hurren; Denis Moss; David A Cooper
Coinfection with A- and B-type Epstein-Barr virus in human immunodeficiency virus-positive subjects.
The Journal of infectious diseases 1990;162(3):643-8.
1990: Scott R Burrows; Ihor Misko; Tom Sculley; C Schmidt; Denis Moss
An Epstein-Barr virus-specific cytotoxic T-cell epitope present on A- and B-type transformants.
Journal of virology 1990;64(8):3974-6.
1990: Scott R Burrows; Ihor Misko; Tom Sculley; C Schmidt; D Gang; Denis Moss
Patterns of reactivity of Epstein-Barr virus-specific T cells in A-type donor cultures after reactivation with autologous A- or B-type transformants.
Cellular immunology 1990;127(1):47-55.
1990: Scott R Burrows; Tom Sculley; Ihor Misko; C Schmidt; Denis Moss
An Epstein-Barr virus-specific cytotoxic T cell epitope in EBV nuclear antigen 3 (EBNA 3).
The Journal of experimental medicine 1990;171(1):345-9.
1989: Tom Sculley; A Apolloni; R Stumm; Denis Moss; N Mueller-Lantczh; Ihor Misko; David A Cooper
Expression of Epstein-Barr virus nuclear antigens 3, 4, and 6 are altered in cell lines containing B-type virus.
Virology 1989;171(2):401-8.
1988: Tom Sculley; S M Cross; P Borrow; David A Cooper
Prevalence of antibodies to Epstein-Barr virus nuclear antigen 2B in persons infected with the human immunodeficiency virus.
The Journal of infectious diseases 1988;158(1):186-92.
1988: Denis Moss; Ihor Misko; Scott R Burrows; K Burman; R McCarthy; Tom Sculley
Cytotoxic T-cell clones discriminate between A- and B-type Epstein-Barr virus transformants.
Nature 1988;331(6158):719-21.
1988: Tom Sculley; D G Sculley; J H Pope; G W Bornkamm; G M Lenoir; A B Rickinson
Epstein-Barr virus nuclear antigens 1 and 2 in Burkitt lymphoma cell lines containing either 'A'- or 'B'-type virus.
Intervirology 1988;29(2):77-85.
1987: Tom Sculley; D J Moss; R A Hazelton; J H Pope
Detection of Epstein-Barr virus strain variants in lymphoblastoid cell lines 'spontaneously' derived from patients with rheumatoid arthritis, infectious mononucleosis and normal controls.
The Journal of general virology 1987;68 ( Pt 8)():2069-78.
1987: K F Wu; Tom Sculley; J H Pope; K A Ellem
[Partial purification and characterization of the tumor growth inhibitor derived from human fibroblast-like cell lines].
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 1987;9(1):7-12.
1986: D G Sculley; Tom Sculley; J H Pope
Reactions of sera from patients with rheumatoid arthritis, systemic lupus erythematosus and infectious mononucleosis to Epstein-Barr virus-induced polypeptides.
The Journal of general virology 1986;67 ( Pt 10)():2253-8.
1986: Tom Sculley; J H Pope; R A Hazelton
Correlation between the presence of antibodies to the Epstein-Barr virus nuclear antigen type 2 and antibodies to the rheumatoid arthritis nuclear antigen in patients with rheumatoid arthritis.
Arthritis and rheumatism 1986;29(8):964-70.
1986: D J Moss; Tom Sculley; J H Pope
Induction of Epstein-Barr virus nuclear antigens.
Journal of virology 1986;58(3):988-90.
1985: Tom Sculley; D G Sculley; J H Pope
Identification of Epstein-Barr virus-induced polypeptides in P3HR-1 cells by protein immunoblot.
The Journal of general virology 1985;66 ( Pt 5)():1113-22.
1984: Tom Sculley; P J Walker; D J Moss; J H Pope
Identification of multiple Epstein-Barr virus-induced nuclear antigens with sera from patients with rheumatoid arthritis.
Journal of virology 1984;52(1):88-93.