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Natalie Searle

Research Profile

Chemicals & Drugs

Phenomena

Living Beings

Mouse

Procedures

Disorders

Malaria

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Publications

TOP 3
Stephen Hindley; Stephen A Ward; Richard C Storr; Natalie L Searle; Patrick G Bray; B Kevin Park; Jill Davies; Paul M O'Neill
Mechanism-based design of parasite-targeted artemisinin derivatives: synthesis and antimalarial activity of new diamine containing analogues.
Paul M O'Neill; Laurence P D Bishop; Natalie L Searle; James L Maggs; Richard C Storr; Stephen A Ward; B Kevin Park; F Mabbs
Biomimetic Fe(II)-mediated degradation of arteflene (Ro-42-1611). The first EPR spin-trapping evidence for the previously postulated secondary carbon-centered cyclohexyl radical.
Paul M O'Neill; Natalie L Searle; K W Kan; Richard C Storr; James L Maggs; Stephen A Ward; Kaylene J Raynes; B Kevin Park
Novel, potent, semisynthetic antimalarial carba analogues of the first-generation 1,2,4-trioxane artemether.

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All Publications

2002: Stephen Hindley; Stephen A Ward; Richard C Storr; Natalie L Searle; Patrick G Bray; B Kevin Park; Jill Davies; Paul M O'Neill
Mechanism-based design of parasite-targeted artemisinin derivatives: synthesis and antimalarial activity of new diamine containing analogues.
Journal of medicinal chemistry 2002;45(5):1052-63.
2000: Paul M O'Neill; Laurence P D Bishop; Natalie L Searle; James L Maggs; Richard C Storr; Stephen A Ward; B Kevin Park; F Mabbs
Biomimetic Fe(II)-mediated degradation of arteflene (Ro-42-1611). The first EPR spin-trapping evidence for the previously postulated secondary carbon-centered cyclohexyl radical.
The Journal of organic chemistry 2000;65(5):1578-82.
1999: Paul M O'Neill; Natalie L Searle; K W Kan; Richard C Storr; James L Maggs; Stephen A Ward; Kaylene J Raynes; B Kevin Park
Novel, potent, semisynthetic antimalarial carba analogues of the first-generation 1,2,4-trioxane artemether.
Journal of medicinal chemistry 1999;42(26):5487-93.

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