FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Cynthia Sears

Research Profile

Living Beings

Chemicals & Drugs

Disorders

Anatomy

Geographic Areas

Brazil

Concepts & Ideas

Co-author Network

Publications

TOP 3
Christine Dejea; Elizabeth C Wick; Cynthia L Sears
Bacterial oncogenesis in the colon.
Elizabeth C Wick; Christine A Iacobuzio-Donahue; Robert E LeBlanc; Guillermo Ortega; Drew M Pardoll; Elizabeth A Platz; Chelsea Robinson; Cynthia L Sears
Shift from pStat6 to pStat3 predominance is associated with inflammatory bowel disease-associated dysplasia.
Cynthia L Sears
In celebration of Sydney M. Finegold, M.D.: bacteroides fragilis in the colon: the good & the bad.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Cynthia Sears (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Christine Dejea; Elizabeth C Wick; Cynthia L Sears
Bacterial oncogenesis in the colon.
Future microbiology 2013;8(4):445-60.
2012: Elizabeth C Wick; Christine A Iacobuzio-Donahue; Robert E LeBlanc; Guillermo Ortega; Drew M Pardoll; Elizabeth A Platz; Chelsea Robinson; Cynthia L Sears
Shift from pStat6 to pStat3 predominance is associated with inflammatory bowel disease-associated dysplasia.
Inflammatory bowel diseases 2012;18(7):1267-74.
2012: Cynthia L Sears
In celebration of Sydney M. Finegold, M.D.: bacteroides fragilis in the colon: the good & the bad.
Anaerobe 2012;18(2):192-6.
2011: Heather M O'Hagan; Cynthia L Sears; Subhojit Sen; Leander Van Neste; Wei Wang; Yang W Zhang; Yi Cai; Robert A Casero; Eriko G Clements; Christina Destefano Shields; Hariharan Easwaran; Stella S Lee; Stephen B Baylin
Oxidative damage targets complexes containing DNA methyltransferases, SIRT1, and polycomb members to promoter CpG Islands.
Cancer cell 2011;20(5):606-19.
2011: Andrew C Goodwin; Amy Hacker-Prietz; David L Huso; Tracy Murray-Stewart; Shervin Rabizadeh; Cynthia L Sears; Christina E Destefano Shields; Patrick M Woster; Shaoguang Wu; XinQun Wu; Robert A Casero
Polyamine catabolism contributes to enterotoxigenic Bacteroides fragilis-induced colon tumorigenesis.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(37):15354-9.
2011: Cynthia L Sears; Drew M Pardoll
Perspective: alpha-bugs, their microbial partners, and the link to colon cancer.
The Journal of infectious diseases 2011;203(3):306-11.
2010: Elizabeth C Wick; Cynthia L Sears
Bacteroides spp. and diarrhea.
Current opinion in infectious diseases 2010;23(5):470-4.
2010: Cynthia L Sears; Sara E Cosgrove
IV or not IV? Just one of the antibiotic questions in Whipple's disease.
Gastroenterology 2010;138(2):422-6.
2010: Franck Housseau; Cynthia L Sears
Enterotoxigenic Bacteroides fragilis (ETBF)-mediated colitis in Min (Apc+/-) mice: a human commensal-based murine model of colon carcinogenesis.
Cell cycle (Georgetown, Tex.) 2010;9(1):3-5.
2009: Shaoguang Wu; Ki-Jong Rhee; Emilia Albesiano; Shervin Rabizadeh; Xinqun Wu; Hung-Rong Yen; David L Huso; frederick brancati; Elizabeth C Wick; Florencia McAllister; Franck Housseau; Drew M Pardoll; Cynthia L Sears
A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses.
Nature medicine 2009;15(9):1016-22.
2009: Cynthia L Sears
Enterotoxigenic Bacteroides fragilis: a rogue among symbiotes.
Clinical microbiology reviews 2009;22(2):349-69, Table of Contents.
2009: Ki-Jong Rhee; Shaoguang Wu; Xinqun Wu; David L Huso; Baktiar O Karim; Augusto A. Franco-Mora; Shervin Rabizadeh; Jonathan E Golub; Lauren E Mathews; Jai Shin; Ryan Sartor; Douglas Golenbock; Abdel Rahim A Hamad; Christine M Gan; Franck Housseau; Cynthia L Sears
Induction of persistent colitis by a human commensal, enterotoxigenic Bacteroides fragilis, in wild-type C57BL/6 mice.
Infection and immunity 2009;77(4):1708-18.
2008: Maria A Said; Trish M Perl; Cynthia L Sears
Healthcare epidemiology: gastrointestinal flu: norovirus in health care and long-term care facilities.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2008;47(9):1202-8.
2008: Cynthia L Sears; Salequl Islam; Amit Saha; Maleka Arjumand; Nur Haque Alam; A S G Faruque; M A Salam; Jai Shin; David Hecht; Andrej Weintraub; RICHARD SACK; Firdausi Qadri
Association of enterotoxigenic Bacteroides fragilis infection with inflammatory diarrhea.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2008;47(6):797-803.
2008: Anita Kohli; Oluma Bushen; Relana C Pinkerton; Eric Houpt; Robert D Newman; Cynthia L Sears; Aldo A M Lima; Richard L Guerrant
Giardia duodenalis assemblage, clinical presentation and markers of intestinal inflammation in Brazilian children.
Transactions of the Royal Society of Tropical Medicine and Hygiene 2008;102(7):718-25.
2008: Shervin Rabizadeh; Cynthia L Sears
New horizons for the infectious diseases specialist: how gut microflora promote health and disease.
Current infectious disease reports 2008;10(2):92-8.
2007: ARUNA SUBRAMANIAN; Cynthia L Sears
Infectious diarrhea in transplant recipients: current challenges and future directions.
Transplant infectious disease : an official journal of the Transplantation Society 2007;9(4):263-4.
2007: Shervin Rabizadeh; Ki-Jong Rhee; Shaoguang Wu; David L Huso; Christine M Gan; Jonathan E Golub; XinQun Wu; Ming Zhang; Cynthia L Sears
Enterotoxigenic bacteroides fragilis: a potential instigator of colitis.
Inflammatory bowel diseases 2007;13(12):1475-83.
2007: Ashwin Balagopal; Cynthia L Sears
Clostridium difficile: new therapeutic options.
Current opinion in pharmacology 2007;7(5):455-8.
2007: Toni M Antalis; Terez Shea-Donohue; Stefanie N Vogel; Cynthia L Sears; Alessio Fasano
Mechanisms of disease: protease functions in intestinal mucosal pathobiology.
Nature clinical practice. Gastroenterology & hepatology 2007;4(7):393-402.
2007: Shaoguang Wu; Ki-Jong Rhee; Ming Zhang; Augusto A. Franco-Mora; Cynthia L Sears
Bacteroides fragilis toxin stimulates intestinal epithelial cell shedding and gamma-secretase-dependent E-cadherin cleavage.
Journal of cell science 2007;120(Pt 11):1944-52.
2007: Oluma Bushen; Anita Kohli; Relana C Pinkerton; Kate Dupnik; Robert D Newman; Cynthia L Sears; Ronald Fayer; Aldo A M Lima; Richard L Guerrant
Heavy cryptosporidial infections in children in northeast Brazil: comparison of Cryptosporidium hominis and Cryptosporidium parvum.
Transactions of the Royal Society of Tropical Medicine and Hygiene 2007;101(4):378-84.
2007: Cynthia L Sears; Beth D Kirkpatrick
Is nitazoxanide an effective treatment for patients with acquired immune deficiency syndrome-related cryptosporidiosis?
Nature clinical practice. Gastroenterology & hepatology 2007;4(3):136-7.
2007: Simy L Buckwold; Nadja B Shoemaker; Cynthia L Sears; Augusto A. Franco-Mora
Identification and characterization of conjugative transposons CTn86 and CTn9343 in Bacteroides fragilis strains.
Applied and environmental microbiology 2007;73(1):53-63.
2006: Kristine ERICA Johnson; Cheleste M Thorpe; Cynthia L Sears
The emerging clinical importance of non-O157 Shiga toxin-producing Escherichia coli.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2006;43(12):1587-95.
2006: Cynthia L Sears; Simy L Buckwold; Jai W Shin; Augusto A. Franco-Mora
The C-terminal region of Bacteroides fragilis toxin is essential to its biological activity.
Infection and immunity 2006;74(10):5595-601.
2006: Shaoguang Wu; Jai Shin; Guangming Zhang; Mitchell Cohen; Augusto A. Franco-Mora; Cynthia L Sears
The Bacteroides fragilis toxin binds to a specific intestinal epithelial cell receptor.
Infection and immunity 2006;74(9):5382-90.
2006: Beth D Kirkpatrick; Francine Noel; Patricia D Rouzier; Jan L Powell; Jean William Pape; Gyrlande Bois; W Kemper Alston; Catherine J Larsson; Katherine M Tenney; Cassandra Ventrone; Cheryl Powden; Meera Sreenivasan; Cynthia L Sears
Childhood cryptosporidiosis is associated with a persistent systemic inflammatory response.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2006;43(5):604-8.
2006: Beth D Kirkpatrick; Christopher D Huston; D Wagner; Francine Noel; P Rouzier; Jean William Pape; Gyrlande Bois; Catherine J Larsson; W Kemper Alston; Katherine M Tenney; Cheryl Powden; J Patrick O'Neill; Cynthia L Sears
Serum mannose-binding lectin deficiency is associated with cryptosporidiosis in young Haitian children.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2006;43(3):289-94.
2006: Shelley S Magill; Christine Shields; Cynthia L Sears; Michael A Choti; William G Merz
Triazole cross-resistance among Candida spp.: case report, occurrence among bloodstream isolates, and implications for antifungal therapy.
Journal of clinical microbiology 2006;44(2):529-35.
2005: Cynthia L Sears
A dynamic partnership: celebrating our gut flora.
Anaerobe 2005;11(5):247-51.
2005: Augusto A. Franco-Mora; Simy L Buckwold; Jai W Shin; Miguel Ascon; Cynthia L Sears
Mutation of the zinc-binding metalloprotease motif affects Bacteroides fragilis toxin activity but does not affect propeptide processing.
Infection and immunity 2005;73(8):5273-7.
2004: Shaoguang Wu; Jan Powell; Nes Mathioudakis; Sheryl Kane; Ellen Fernandez; Cynthia L Sears
Bacteroides fragilis enterotoxin induces intestinal epithelial cell secretion of interleukin-8 through mitogen-activated protein kinases and a tyrosine kinase-regulated nuclear factor-kappaB pathway.
Infection and immunity 2004;72(10):5832-9.
2004: Lisa A Spacek; Bryan P Hurley; David W K Acheson; Alexander Granok; Allan Currie; Kirk Doing; Cynthia L Sears
Shiga toxin-producing Escherichia coli as a possible etiological agent of chronic diarrhea.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2004;39(5):e46-8.
2003: Shaoguang Wu; Patrice J Morin; Djik Maouyo; Cynthia L Sears
Bacteroides fragilis enterotoxin induces c-Myc expression and cellular proliferation.
Gastroenterology 2003;124(2):392-400.
2002: Augusto A. Franco-Mora; Rodney K Cheng; Alan Goodman; Cynthia L Sears
Modulation of bft expression by the Bacteroides fragilis pathogenicity island and its flanking region.
Molecular microbiology 2002;45(4):1067-77.
2002: Beth D Kirkpatrick; Michelle M Daniels; Sonic Jean; Jean William Pape; Christopher Karp; Benjamin Littenberg; Daniel W Fitzgerald; Howard M Lederman; James P Nataro; Cynthia L Sears
Cryptosporidiosis stimulates an inflammatory intestinal response in malnourished Haitian children.
The Journal of infectious diseases 2002;186(1):94-101.
2002: Shaoguang Wu; Lawrence A Dreyfus; Arthur tzianabos; Chika Hayashi; Cynthia L Sears
Diversity of the metalloprotease toxin produced by enterotoxigenic Bacteroides fragilis.
Infection and immunity 2002;70(5):2463-71.
2001: Cynthia L Sears
The toxins of Bacteroides fragilis.
Toxicon : official journal of the International Society on Toxinology 2001;39(11):1737-46.
2001: David W K Acheson; Cynthia L Sears
Dangers of empiric oral ciprofloxacin in the treatment of acute inflammatory diarrhea in children.
The Pediatric infectious disease journal 2001;20(8):817-8.
2001: Robert D Newman; Sean Moore; Aldo A M Lima; James P Nataro; Richard L Guerrant; Cynthia L Sears
A longitudinal study of Giardia lamblia infection in north-east Brazilian children.
Tropical medicine & international health : TM & IH 2001;6(8):624-34.
2001: James P Nataro; Cynthia L Sears
Infectious causes of persistent diarrhea.
The Pediatric infectious disease journal 2001;20(2):195-6.
2001: Fernando Navarro-García; Adrian Canizalez-Roman; J Luna; Cynthia L Sears; James P Nataro
Plasmid-encoded toxin of enteroaggregative Escherichia coli is internalized by epithelial cells.
Infection and immunity 2001;69(2):1053-60.
2000: Cynthia L Sears
Molecular physiology and pathophysiology of tight junctions V. assault of the tight junction by enteric pathogens.
American journal of physiology. Gastrointestinal and liver physiology 2000;279(6):G1129-34.
2000: Michele Trucksis; T L Conn; Steven Wasserman; Cynthia L Sears
Vibrio cholerae ACE stimulates Ca(2+)-dependent Cl(-)/HCO(3)(-) secretion in T84 cells in vitro.
American journal of physiology. Cell physiology 2000;279(3):C567-77.
2000: Aldo A M Lima; Sean Moore; MS Barboza; A M Soares; M A Schleupner; Robert D Newman; Cynthia L Sears; James P Nataro; D P Fedorko; T Wuhib; John B Schorling; Richard L Guerrant
Persistent diarrhea signals a critical period of increased diarrhea burdens and nutritional shortfalls: a prospective cohort study among children in northeastern Brazil.
The Journal of infectious diseases 2000;181(5):1643-51.
1999: Augusto A. Franco-Mora; R K Cheng; G T Chung; Shaoguang Wu; Hee-Bok Oh; Cynthia L Sears
Molecular evolution of the pathogenicity island of enterotoxigenic Bacteroides fragilis strains.
Journal of bacteriology 1999;181(21):6623-33.
1999: G T Chung; Augusto A. Franco-Mora; Shaoguang Wu; Gi-Eun Rhie; R Cheng; Hee-Bok Oh; Cynthia L Sears
Identification of a third metalloprotease toxin gene in extraintestinal isolates of Bacteroides fragilis.
Infection and immunity 1999;67(9):4945-9.
1999: Robert D Newman; Cynthia L Sears; Sean Moore; James P Nataro; T Wuhib; D A Agnew; Richard L Guerrant; Aldo A M Lima
Longitudinal study of Cryptosporidium infection in children in northeastern Brazil.
The Journal of infectious diseases 1999;180(1):167-75.
1999: Fernando Navarro-García; Cynthia L Sears; Carlos Eslava; Alejandro Cravioto; James P Nataro
Cytoskeletal effects induced by pet, the serine protease enterotoxin of enteroaggregative Escherichia coli.
Infection and immunity 1999;67(5):2184-92.
1999: Martin Riegler; M Lotz; Cynthia L Sears; Charalabos Pothoulakis; Ignazio Castagliuolo; C C Wang; R Sedivy; T Sogukoglu; Enrico P Cosentini; Georg Bischof; Wolfgang Feil; Bela Teleky; Gerhard Hamilton; J Thomas LaMont; Etienne Wenzl
Bacteroides fragilis toxin 2 damages human colonic mucosa in vitro.
Gut 1999;44(4):504-10.
1998: J A Lumadue; Yukari C Manabe; Richard D Moore; P C Belitsos; Cynthia L Sears; Douglas P Clark
A clinicopathologic analysis of AIDS-related cryptosporidiosis.
AIDS (London, England) 1998;12(18):2459-66.
1998: Shaoguang Wu; K C Lim; Judy Huang; RF Saidi; Cynthia L Sears
Bacteroides fragilis enterotoxin cleaves the zonula adherens protein, E-cadherin.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(25):14979-84.
1998: Yukari C Manabe; Douglas P Clark; Richard D Moore; J A Lumadue; H R Dahlman; P C Belitsos; Richard E Chaisson; Cynthia L Sears
Cryptosporidiosis in patients with AIDS: correlates of disease and survival.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1998;27(3):536-42.
1998: D G Agnew; Aldo A M Lima; Robert D Newman; T Wuhib; Richard D Moore; Richard L Guerrant; Cynthia L Sears
Cryptosporidiosis in northeastern Brazilian children: association with increased diarrhea morbidity.
The Journal of infectious diseases 1998;177(3):754-60.
1997: F G Chambers; S S Koshy; RF Saidi; Douglas P Clark; Richard D Moore; Cynthia L Sears
Bacteroides fragilis toxin exhibits polar activity on monolayers of human intestinal epithelial cells (T84 cells) in vitro.
Infection and immunity 1997;65(9):3561-70.
1997: A E Fiore; J M Michalski; R G Russell; Cynthia L Sears; James B Kaper
Cloning, characterization, and chromosomal mapping of a phospholipase (lecithinase) produced by Vibrio cholerae.
Infection and immunity 1997;65(8):3112-7.
1997: Augusto A. Franco-Mora; L M Mundy; Michele Trucksis; Shaoguang Wu; James B Kaper; Cynthia L Sears
Cloning and characterization of the Bacteroides fragilis metalloprotease toxin gene.
Infection and immunity 1997;65(3):1007-13.
1997: RF Saidi; K Jaeger; MH Montrose; Shaoguang Wu; Cynthia L Sears
Bacteroides fragilis toxin rearranges the actin cytoskeleton of HT29/C1 cells without direct proteolysis of actin or decrease in F-actin content.
Cell motility and the cytoskeleton 1997;37(2):159-65.
1996: L L Braga; Aldo A M Lima; Cynthia L Sears; Robert D Newman; T Wuhib; C A Paiva; Richard L Guerrant; Barbara J Mann
Seroepidemiology of Entamoeba histolytica in a slum in northeastern Brazil.
The American journal of tropical medicine and hygiene 1996;55(6):693-7.
1996: R F Saidi; Cynthia L Sears
Bacteroides fragilis toxin rapidly intoxicates human intestinal epithelial cells (HT29/C1) in vitro.
Infection and immunity 1996;64(12):5029-34.
1996: S S Koshy; MH Montrose; Cynthia L Sears
Human intestinal epithelial cells swell and demonstrate actin rearrangement in response to the metalloprotease toxin of Bacteroides fragilis.
Infection and immunity 1996;64(12):5022-8.
1996: James P Nataro; Susan Hicks; A D Phillips; P A Vial; Cynthia L Sears
T84 cells in culture as a model for enteroaggregative Escherichia coli pathogenesis.
Infection and immunity 1996;64(11):4761-8.
1996: N P O'Grady; Cynthia L Sears
Therapeutic dilemmas in the care of a human immunodeficiency virus-infected patient with vasculitis: case report.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1996;23(3):659-61.
1996: Firdausi Qadri; M G Mohi; A Chowdhury; Khorshed Alam; Tasnim Azim; Cynthia L Sears; RICHARD SACK; M J Albert
Monoclonal antibodies to the enterotoxin of Bacteroides fragilis: production, characterization, and immunodiagnostic application.
Clinical and diagnostic laboratory immunology 1996;3(5):608-10.
1996: Linda M Mundy; Cynthia L Sears
Detection of toxin production by Bacteroides fragilis: assay development and screening of extraintestinal clinical isolates.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1996;23(2):269-76.
1996: Douglas P Clark; Cynthia L Sears
The pathogenesis of cryptosporidiosis.
Parasitology today (Personal ed.) 1996;12(6):221-5.
1996: Cynthia L Sears; James B Kaper
Enteric bacterial toxins: mechanisms of action and linkage to intestinal secretion.
Microbiological reviews 1996;60(1):167-215.
1995: Cynthia L Sears; F Firoozmand; A Mellander; F G Chambers; I G Eromar; Alice G M Bot; Bob J Scholte; Hugo R de Jonge; Mark Donowitz
Genistein and tyrphostin 47 stimulate CFTR-mediated Cl- secretion in T84 cell monolayers.
The American journal of physiology 1995;269(6 Pt 1):G874-82.
1995: Cynthia L Sears; L L Myers; Audrey Lazenby; R L Van Tassell
Enterotoxigenic Bacteroides fragilis.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1995;20 Suppl 2():S142-8.
1995: L K Dropulic; JO LESLIE; Lois Eldred; Jonathan M Zenilman; Cynthia L Sears
Clinical manifestations and risk factors of Pseudomonas aeruginosa infection in patients with AIDS.
The Journal of infectious diseases 1995;171(4):930-7.
1995: V H San Joaquin; J C Griffis; C Lee; Cynthia L Sears
Association of Bacteroides fragilis with childhood diarrhea.
Scandinavian journal of infectious diseases 1995;27(3):211-5.
1994: Robert D Newman; S X Zu; T Wuhib; Aldo A M Lima; Richard L Guerrant; Cynthia L Sears
Household epidemiology of Cryptosporidium parvum infection in an urban community in northeast Brazil.
Annals of internal medicine 1994;120(6):500-5.
1994: Cynthia L Sears; R L Guerrant
Cryptosporidiosis: the complexity of intestinal pathophysiology.
Gastroenterology 1994;106(1):252-4.
1993: William R Bishai; Cynthia L Sears
Food poisoning syndromes.
Gastroenterology clinics of North America 1993;22(3):579-608.
1993: Robert D Newman; K L Jaeger; T Wuhib; Aldo A M Lima; Richard L Guerrant; Cynthia L Sears
Evaluation of an antigen capture enzyme-linked immunosorbent assay for detection of Cryptosporidium oocysts.
Journal of clinical microbiology 1993;31(8):2080-4.
1993: Robert D Newman; T Wuhib; Aldo A M Lima; Richard L Guerrant; Cynthia L Sears
Environmental sources of Cryptosporidium in an urban slum in northeastern Brazil.
The American journal of tropical medicine and hygiene 1993;49(2):270-5.
1992: J K Crane; M S Wehner; E J Bolen; Julianne J Sando; Joel Linden; Richard L Guerrant; Cynthia L Sears
Regulation of intestinal guanylate cyclase by the heat-stable enterotoxin of Escherichia coli (STa) and protein kinase C.
Infection and immunity 1992;60(12):5004-12.
1992: John G Bartlett; P C Belitsos; Cynthia L Sears
AIDS enteropathy.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1992;15(4):726-35.
1983: M E Charlson; R P Cohen; Cynthia L Sears
General medicine consultation. Lessons from a clinical service.
The American journal of medicine 1983;75(1):121-8.
1983: Cynthia L Sears; M E Charlson
The effectiveness of a consultation. Compliance with initial recommendations.
The American journal of medicine 1983;74(5):870-6.