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Christopher Secombes

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
47
Zou, Jun
23
Wang, Tiehui
20
Collet, Bertrand
15
Bird, Steve
15
Cunningham, Charles
14
Laing, Kerry
13
Scapigliati, Giuseppe
12
Buonocore, Francesco
10
Bols, Niels
10
Ellis, Anthony
9
Holland, Jason
9
Rowley, Andrew
7
Peddie, Scott
6
Randelli, Elisa
6
Hong, Suhee

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Publications

TOP 3
Casadei Elisa; Wang Tiehui; Zou Jun; González Vecino Jose L; Wadsworth Simon; Secombes Christopher J
Characterization of three novel beta-defensin antimicrobial peptides in rainbow trout (Oncorhynchus mykiss).
Díaz-Rosales P; Bird S; Wang T H; Fujiki K; Davidson W S; Zou J; Secombes C J
Rainbow trout interleukin-2: cloning, expression and bioactivity analysis.
Gao Q; Nie P; Thompson K D; Adams A; Wang T; Secombes C J; Zou J
The search for the IFN-gamma receptor in fish: Functional and expression analysis of putative binding and signalling chains in rainbow trout Oncorhynchus mykiss.

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All Publications

2009: Casadei Elisa; Wang Tiehui; Zou Jun; González Vecino Jose L; Wadsworth Simon; Secombes Christopher J
Characterization of three novel beta-defensin antimicrobial peptides in rainbow trout (Oncorhynchus mykiss).
Molecular immunology 2009;46(16):3358-66.
2009: Díaz-Rosales P; Bird S; Wang T H; Fujiki K; Davidson W S; Zou J; Secombes C J
Rainbow trout interleukin-2: cloning, expression and bioactivity analysis.
Fish & shellfish immunology 2009;27(3):414-22.
2009: Gao Q; Nie P; Thompson K D; Adams A; Wang T; Secombes C J; Zou J
The search for the IFN-gamma receptor in fish: Functional and expression analysis of putative binding and signalling chains in rainbow trout Oncorhynchus mykiss.
Developmental and comparative immunology 2009;33(8):920-31.
2009: Wang Tiehui; Bird Steve; Koussounadis Antonis; Holland Jason W; Carrington Allison; Zou Jun; Secombes Christopher J
Identification of a novel IL-1 cytokine family member in teleost fish.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(2):962-74.
2009: Wang Tiehui; Secombes Christopher J
Identification and expression analysis of two fish-specific IL-6 cytokine family members, the ciliary neurotrophic factor (CNTF)-like and M17 genes, in rainbow trout Oncorhynchus mykiss.
Molecular immunology 2009;46(11-12):2290-8.
2009: Corripio-Miyar Yolanda; Zou Jun; Richmond Heather; Secombes Chris J
Identification of interleukin-22 in gadoids and examination of its expression level in vaccinated fish.
Molecular immunology 2009;46(10):2098-106.
2009: Chang Mingxian; Nie Pin; Collet Bertrand; Secombes Christopher J; Zou Jun
Identification of an additional two-cysteine containing type I interferon in rainbow trout Oncorhynchus mykiss provides evidence of a major gene duplication event within this gene family in teleosts.
Immunogenetics 2009;61(4):315-25.
2009: Østergaard Anders E; Martin Samuel A M; Wang Tiehui; Stet René J M; Secombes Christopher J
Rainbow trout (Oncorhynchus mykiss) possess multiple novel immunoglobulin-like transcripts containing either an ITAM or ITIMs.
Developmental and comparative immunology 2009;33(4):525-32.
2009: Casani Daniela; Randelli Elisa; Costantini Susan; Facchiano Angelo M; Zou Jun; Martin Sam; Secombes Chris J; Scapigliati Giuseppe; Buonocore Francesco
Molecular characterisation and structural analysis of an interferon homologue in sea bass (Dicentrarchus labrax L.).
Molecular immunology 2009;46(5):943-52.
2008: Holland J W; Bird S; Williamson B; Woudstra C; Mustafa A; Wang T; Zou J; Blaney S C; Collet B; Secombes C J
Molecular characterization of IRF3 and IRF7 in rainbow trout, Oncorhynchus mykiss: functional analysis and transcriptional modulation.
Molecular immunology 2008;46(2):269-85.
2008: Secombes Chris
Will advances in fish immunology change vaccination strategies?
Fish & shellfish immunology 2008;25(4):409-16.
2008: Wang Tiehui; Hanington Patrick C; Belosevic Miodrag; Secombes Christopher J
Two macrophage colony-stimulating factor genes exist in fish that differ in gene organization and are differentially expressed.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(5):3310-22.
2008: Castro Rosario; Martin Samuel A M; Bird Steve; Lamas Jesús; Secombes Christopher J
Characterisation of gamma-interferon responsive promoters in fish.
Molecular immunology 2008;45(12):3454-62.
2008: Buonocore Francesco; Randelli Elisa; Casani Daniela; Guerra Laura; Picchietti Simona; Costantini Susan; Facchiano Angelo M; Zou Jun; Secombes Chris J; Scapigliati Giuseppe
A CD4 homologue in sea bass (Dicentrarchus labrax): molecular characterization and structural analysis.
Molecular immunology 2008;45(11):3168-77.
2008: Kono Tomoya; Bird Steve; Sonoda Kohei; Savan Ram; Secombes Christopher J; Sakai Masahiro
Characterization and expression analysis of an interleukin-7 homologue in the Japanese pufferfish, Takifugu rubripes.
The FEBS journal 2008;275(6):1213-26.
2008: Wang Tiehui; Secombes Christopher J
Rainbow trout suppressor of cytokine signalling (SOCS)-1, 2 and 3: molecular identification, expression and modulation.
Molecular immunology 2008;45(5):1449-57.
2008: Harun Nor Omaima; Zou Jun; Zhang Yang-An; Nie Pin; Secombes Chris J
The biological effects of rainbow trout (Oncorhynchus mykiss) recombinant interleukin-8.
Developmental and comparative immunology 2008;32(6):673-81.
2007: Martin S A M; Taggart J B; Seear P; Bron J E; Talbot R; Teale A J; Sweeney G E; Høyheim B; Houlihan D F; Tocher D R; Zou J; Secombes C J
Interferon type I and type II responses in an Atlantic salmon (Salmo salar) SHK-1 cell line by the salmon TRAITS/SGP microarray.
Physiological genomics 2007;32(1):33-44.
2007: Jørgensen Jorunn B; Johansen Audny; Hegseth Marit N; Zou Jun; Robertsen Børre; Collet Bertrand; Secombes Christopher J
A recombinant CHSE-214 cell line expressing an Mx1 promoter-reporter system responds to both interferon type I and type II from salmonids and represents a versatile tool to study the IFN-system in teleost fish.
Fish & shellfish immunology 2007;23(6):1294-303.
2007: Hanington Patrick C; Wang Tiehui; Secombes Christopher J; Belosevic Miodrag
Growth factors of lower vertebrates: characterization of goldfish (Carassius auratus L.) macrophage colony-stimulating factor-1.
The Journal of biological chemistry 2007;282(44):31865-72.
2007: Carrington Allison C; Secombes Christopher J
CpG oligodeoxynucleotides up-regulate antibacterial systems and induce protection against bacterial challenge in rainbow trout (Oncorhynchus mykiss).
Fish & shellfish immunology 2007;23(4):781-92.
2007: Mulder I E; Wadsworth S; Secombes C J
Cytokine expression in the intestine of rainbow trout (Oncorhynchus mykiss) during infection with Aeromonas salmonicida.
Fish & shellfish immunology 2007;23(4):747-59.
2007: Zou Jun; Tafalla Carolina; Truckle Jonathan; Secombes Chris J
Identification of a second group of type I IFNs in fish sheds light on IFN evolution in vertebrates.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(6):3859-71.
2007: Nascimento Diana S; Pereira Pedro J B; Reis Marta I R; do Vale Ana; Zou Jun; Silva Manuel T; Secombes Christopher J; dos Santos Nuno M S
Molecular cloning and expression analysis of sea bass (Dicentrarchus labrax L.) tumor necrosis factor-alpha (TNF-alpha).
Fish & shellfish immunology 2007;23(3):701-10.
2007: Wang Tiehui; Holland Jason W; Carrington Allison; Zou Jun; Secombes Christopher J
Molecular and functional characterization of IL-15 in rainbow trout Oncorhynchus mykiss: a potent inducer of IFN-gamma expression in spleen leukocytes.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(3):1475-88.
2007: Corripio-Miyar Y; Mazorra de Quero C; Treasurer J W; Ford L; Smith P D; Secombes C J
Vaccination experiments in the gadoid haddock, Melanogrammus aeglefinus L., against the bacterial pathogen Vibrio anguillarum.
Veterinary immunology and immunopathology 2007;118(1-2):147-53.
2007: Corripio-Miyar Y; Bird S; Treasurer J W; Secombes C J
RAG-1 and IgM genes, markers for early development of the immune system in the gadoid haddock, Melanogrammus aeglefinus, L.
Fish & shellfish immunology 2007;23(1):71-85.
2007: Martin Samuel A M; Mohanty Bimal P; Cash Phillip; Houlihan Dominic F; Secombes Christopher J
Proteome analysis of the Atlantic salmon (Salmo salar) cell line SHK-1 following recombinant IFN-gamma stimulation.
Proteomics 2007;7(13):2275-86.
2007: Nascimento Diana S; do Vale Ana; Tomás Ana M; Zou Jun; Secombes Christopher J; dos Santos Nuno M S
Cloning, promoter analysis and expression in response to bacterial exposure of sea bass (Dicentrarchus labrax L.) interleukin-12 p40 and p35 subunits.
Molecular immunology 2007;44(9):2277-91.
2007: McBeath A J A; Snow M; Secombes C J; Ellis A E; Collet B
Expression kinetics of interferon and interferon-induced genes in Atlantic salmon (Salmo salar) following infection with infectious pancreatic necrosis virus and infectious salmon anaemia virus.
Fish & shellfish immunology 2007;22(3):230-41.
2007: Corripio-Miyar Y; Bird S; Tsamopoulos K; Secombes C J
Cloning and expression analysis of two pro-inflammatory cytokines, IL-1 beta and IL-8, in haddock (Melanogrammus aeglefinus).
Molecular immunology 2007;44(6):1361-73.
2007: Collet Bertrand; Munro Eann S; Gahlawat Suresh; Acosta Felix; Garcia Jose; Roemelt Christina; Zou Jun; Secombes Christopher J; Ellis Anthony E
Infectious pancreatic necrosis virus suppresses type I interferon signalling in rainbow trout gonad cell line but not in Atlantic salmon macrophages.
Fish & shellfish immunology 2007;22(1-2):44-56.
2007: Roca Francisco J; Cayuela María L; Secombes Chris J; Meseguer José; Mulero Victoriano
Post-transcriptional regulation of cytokine genes in fish: A role for conserved AU-rich elements located in the 3'-untranslated region of their mRNAs.
Molecular immunology 2007;44(4):472-8.
2007: Zou Jun; Mercier Claire; Koussounadis Antonis; Secombes Chris
Discovery of multiple beta-defensin like homologues in teleost fish.
Molecular immunology 2007;44(4):638-47.
2007: Shao Cui-Ying; Secombes Chris J; Porter Andrew J
Rapid isolation of IgNAR variable single-domain antibody fragments from a shark synthetic library.
Molecular immunology 2007;44(4):656-65.
2007: Martin Samuel A M; Zou Jun; Houlihan Dominic F; Secombes Christopher J
Directional responses following recombinant cytokine stimulation of rainbow trout (Oncorhynchus mykiss) RTS-11 macrophage cells as revealed by transcriptome profiling.
BMC genomics 2007;8():150.
2006: Laing Kerry J; Zou Jun J; Purcell Maureen K; Phillips Ruth; Secombes Christopher J; Hansen John D
Evolution of the CD4 family: teleost fish possess two divergent forms of CD4 in addition to lymphocyte activation gene-3.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(6):3939-51.
2006: Carrington Allison C; Secombes Christopher J
A review of CpGs and their relevance to aquaculture.
Veterinary immunology and immunopathology 2006;112(3-4):87-101.
2006: Benedetti S; Randelli E; Buonocore F; Zou J; Secombes C J; Scapigliati G
Evolution of cytokine responses: IL-1beta directly affects intracellular Ca2+ concentration of teleost fish leukocytes through a receptor-mediated mechanism.
Cytokine 2006;34(1-2):9-16.
2006: Martin S A M; Blaney S C; Houlihan D F; Secombes C J
Transcriptome response following administration of a live bacterial vaccine in Atlantic salmon (Salmo salar).
Molecular immunology 2006;43(11):1900-11.
2006: Buonocore Francesco; Randelli Elisa; Bird Steve; Secombes Chris J; Costantini Susan; Facchiano Angelo; Mazzini Massimo; Scapigliati Giuseppe
The CD8alpha from sea bass (Dicentrarchus labrax L.): Cloning, expression and 3D modelling.
Fish & shellfish immunology 2006;20(4):637-46.
2006: Kono Tomoya; Zou Jun; Bird Steve; Savan Ram; Sakai Masahiro; Secombes Christopher J
Identification and expression analysis of lymphotoxin-beta like homologues in rainbow trout Oncorhynchus mykiss.
Molecular immunology 2006;43(9):1390-401.
2006: McBeath Alastair J A; Collet Bertrand; Paley Richard; Duraffour Sophie; Aspehaug Vidar; Biering Eirik; Secombes Christopher J; Snow Michael
Identification of an interferon antagonist protein encoded by segment 7 of infectious salmon anaemia virus.
Virus research 2006;115(2):176-84.
2006: Chang Chin-I; Zhang Yong-An; Zou Jun; Nie Pin; Secombes Christopher J
Two cathelicidin genes are present in both rainbow trout (Oncorhynchus mykiss) and atlantic salmon (Salmo salar).
Antimicrobial agents and chemotherapy 2006;50(1):185-95.
2006: Bird S; Zou J; Secombes C J
Advances in fish cytokine biology give clues to the evolution of a complex network.
Current pharmaceutical design 2006;12(24):3051-69.
2006: Reddick Jennifer I; Goostrey Anna; Secombes Chris J
Cloning of iNOS in the small spotted catshark (Scyliorhinus canicula).
Developmental and comparative immunology 2006;30(11):1009-22.
2006: Robertsen Børre; Zou Jun; Secombes Chris; Leong Jo-Ann
Molecular and expression analysis of an interferon-gamma-inducible guanylate-binding protein from rainbow trout (Oncorhynchus mykiss).
Developmental and comparative immunology 2006;30(11):1023-33.
2005: Quabius Elgar Susanne; Krupp Guido; Secombes Christopher J
Polychlorinated biphenyl 126 affects expression of genes involved in stress-immune interaction in primary cultures of rainbow trout anterior kidney cells.
Environmental toxicology and chemistry / SETAC 2005;24(12):3053-60.
2005: Buonocore Francesco; Forlenza Maria; Randelli Elisa; Benedetti Stefania; Bossù Paola; Meloni Sabrina; Secombes Christopher J; Mazzini Massimo; Scapigliati Giuseppe
Biological activity of sea bass (Dicentrarchus labrax L.) recombinant interleukin-1beta.
Marine biotechnology (New York, N.Y.) 2005;7(6):609-17.
2005: Zou Jun; Carrington Allison; Collet Bertrand; Dijkstra Johannes Martinus; Yoshiura Yasutoshi; Bols Niels; Secombes Chris
Identification and bioactivities of IFN-gamma in rainbow trout Oncorhynchus mykiss: the first Th1-type cytokine characterized functionally in fish.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(4):2484-94.
2005: Boshra Hani; Wang Tiehui; Hove-Madsen Leif; Hansen John; Li Jun; Matlapudi Anjun; Secombes Christopher J; Tort Lluis; Sunyer J Oriol
Characterization of a C3a receptor in rainbow trout and Xenopus: the first identification of C3a receptors in nonmammalian species.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(4):2427-37.
2005: Chang Chin-I; Pleguezuelos Olga; Zhang Yong-An; Zou Jun; Secombes Christopher J
Identification of a novel cathelicidin gene in the rainbow trout, Oncorhynchus mykiss.
Infection and immunity 2005;73(8):5053-64.
2005: Stansberg Christine; Subramaniam Sumathi; Collet Bertrand; Secombes Christopher J; Cunningham Charles
Cloning of the Atlantic salmon (Salmo salar) IL-1 receptor associated protein.
Fish & shellfish immunology 2005;19(1):53-65.
2005: Taylor Irene S; Adam Berit; Veverková Marie; Tatner Mary F; Low Carol; Secombes Chris; Birkbeck T Harry
T-cell antigen receptor genes in turbot (Scophthalmus maximus L.).
Fish & shellfish immunology 2005;18(5):445-8.
2005: Wang Tiehui; Holland Jason W; Bols Niels; Secombes Christopher J
Cloning and expression of the first nonmammalian interleukin-11 gene in rainbow trout Oncorhynchus mykiss.
The FEBS journal 2005;272(5):1136-47.
2005: Bird Steve; Zou Jun; Kono Tomoya; Sakai Masahiro; Dijkstra Johannes Martinus; Secombes Chris
Characterisation and expression analysis of interleukin 2 (IL-2) and IL-21 homologues in the Japanese pufferfish, Fugu rubripes, following their discovery by synteny.
Immunogenetics 2005;56(12):909-23.
2005: Collet Bertrand; Secombes Christopher J
Construction and analysis of a secreting expression vector for fish cells.
Vaccine 2005;23(13):1534-9.
2005: Secombes C J; Bird S; Zou J
Adaptive immunity in teleosts: cellular immunity.
Developments in biologicals 2005;121():25-32.
2005: Bird Steve; Zou Jun; Savan Ram; Kono Tomoya; Sakai Masahiro; Woo Janet; Secombes Chris
Characterisation and expression analysis of an interleukin 6 homologue in the Japanese pufferfish, Fugu rubripes.
Developmental and comparative immunology 2005;29(9):775-89.
2005: Tafalla C; Coll J; Secombes C J
Expression of genes related to the early immune response in rainbow trout (Oncorhynchus mykiss) after viral haemorrhagic septicemia virus (VHSV) infection.
Developmental and comparative immunology 2005;29(7):615-26.
2005: Goostrey Anna; Jones Gareth; Secombes Christopher J
Isolation and characterization of CXC receptor genes in a range of elasmobranchs.
Developmental and comparative immunology 2005;29(3):229-42.
2004: Ohta Yuko; Landis Eric; Boulay Thomas; Phillips Ruth B; Collet Bertrand; Secombes Chris J; Flajnik Martin F; Hansen John D
Homologs of CD83 from elasmobranch and teleost fish.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(7):4553-60.
2004: Zhang Yong-An; Zou Jun; Chang Chin-I; Secombes Christopher J
Discovery and characterization of two types of liver-expressed antimicrobial peptide 2 (LEAP-2) genes in rainbow trout.
Veterinary immunology and immunopathology 2004;101(3-4):259-69.
2004: Carrington Allison C; Collet Bertrand; Holland Jason W; Secombes Christopher J
CpG oligodeoxynucleotides stimulate immune cell proliferation but not specific antibody production in rainbow trout (Oncorhynchus mykiss).
Veterinary immunology and immunopathology 2004;101(3-4):211-22.
2004: Zou Jun; Yoshiura Yasutoshi; Dijkstra Johannes Martinus; Sakai Masahiro; Ototake Mitsuru; Secombes Chris
Identification of an interferon gamma homologue in Fugu, Takifugu rubripes.
Fish & shellfish immunology 2004;17(4):403-9.
2004: Salinas I; Lockhart K; Bowden T J; Collet B; Secombes C J; Ellis A E
An assessment of immunostimulants as Mx inducers in Atlantic salmon (Salmo salar L.) parr and the effect of temperature on the kinetics of Mx responses.
Fish & shellfish immunology 2004;17(2):159-70.
2004: Laing Kerry J; Secombes Christopher J
Trout CC chemokines: comparison of their sequences and expression patterns.
Molecular immunology 2004;41(8):793-808.
2004: Collet Bertrand; Boudinot Pierre; Benmansour Abdenour; Secombes Christopher J
An Mx1 promoter-reporter system to study interferon pathways in rainbow trout.
Developmental and comparative immunology 2004;28(7-8):793-801.
2004: Zou Jun; Bird Steve; Truckle Jonathan; Bols Niels; Horne Mike; Secombes Chris
Identification and expression analysis of an IL-18 homologue and its alternatively spliced form in rainbow trout (Oncorhynchus mykiss).
European journal of biochemistry / FEBS 2004;271(10):1913-23.
2004: Laing Kerry J; Secombes Christopher J
Chemokines.
Developmental and comparative immunology 2004;28(5):443-60.
2004: Scapigliati Giuseppe; Costantini Susan; Colonna Giovanni; Facchiano Angelo; Buonocore Francesco; Bossù Paola; Cunningham Charles; Holland Jason W; Secombes Christopher J
Modelling of fish interleukin-1 and its receptor.
Developmental and comparative immunology 2004;28(5):429-41.
2004: Secombes Chris; Cunningham Charlie
Cytokines: an evolutionary perspective.
Developmental and comparative immunology 2004;28(5):373-4.
2004: Hong Suhee; Zou Jun; Collet Bertrand; Bols Niels C; Secombes Chris J
Analysis and characterisation of IL-1beta processing in rainbow trout, Oncorhynchus mykiss.
Fish & shellfish immunology 2004;16(3):453-9.
2004: Wang Tiehui; Johnson Niel; Zou Jun; Bols Niels; Secombes Christopher J
Sequencing and expression of the second allele of the interleukin-1beta1 gene in rainbow trout (Oncorhynchus mykiss): identification of a novel SINE in the third intron.
Fish & shellfish immunology 2004;16(3):335-58.
2004: Johansen Audny; Collet Bertrand; Sandaker Elin; Secombes Christopher J; Jørgensen Jorunn B
Quantification of Atlantic salmon type-I interferon using an Mx1 promoter reporter gene assay.
Fish & shellfish immunology 2004;16(2):173-84.
2004: Lindenstrøm Thomas; Secombes Christopher J; Buchmann Kurt
Expression of immune response genes in rainbow trout skin induced by Gyrodactylus derjavini infections.
Veterinary immunology and immunopathology 2004;97(3-4):137-48.
2004: Tafalla C; Aranguren R; Secombes C J; Figueras A; Novoa B
Cloning and analysis of expression of a gilthead sea bream (Sparus aurata) Mx cDNA.
Fish & shellfish immunology 2004;16(1):11-24.
2004: Buonocore Francesco; Mazzini Massimo; Forlenza Maria; Randelli Elisa; Secombes Christopher J; Zou Jun; Scapigliati Giuseppe
Expression in Escherchia coli and purification of sea bass (Dicentrarchus labrax) interleukin 1beta, a possible immunoadjuvant in aquaculture.
Marine biotechnology (New York, N.Y.) 2004;6(1):53-9.
2004: Koussounadis Antonis I; Ritchie David W; Kemp Graham J L; Secombes Chris J
Analysis of fish IL-1beta and derived peptide sequences indicates conserved structures with species-specific IL-1 receptor binding: implications for pharmacological design.
Current pharmaceutical design 2004;10(31):3857-71.
2003: Wang Tiehui; Secombes Christopher J
Complete sequencing and expression of three complement components, C1r, C4 and C1 inhibitor, of the classical activation pathway of the complement system in rainbow trout Oncorhynchus mykiss.
Immunogenetics 2003;55(9):615-28.
2003: Zou J; Secombes C J; Long S; Miller N; Clem L W; Chinchar V G
Molecular identification and expression analysis of tumor necrosis factor in channel catfish (Ictalurus punctatus).
Developmental and comparative immunology 2003;27(10):845-58.
2003: Collet Bertrand; McDonald Colin; Secombes Christopher J
The promoter for the Interferon Regulatory Factor (IRF)-2 in the rainbow trout Oncorhynchus mykiss: cloning and reporter gene activity.
Fish & shellfish immunology 2003;15(5):473-7.
2003: Peddie Scott; McLauchlan Pamela E; Ellis Anthony E; Secombes Christopher J
Effect of intraperitoneally administered IL-1beta-derived peptides on resistance to viral haemorrhagic septicaemia in rainbow trout Oncorhynchus mykiss.
Diseases of aquatic organisms 2003;56(3):195-200.
2003: Zou J; Peddie S; Scapigliati G; Zhang Y; Bols N C; Ellis A E; Secombes C J
Functional characterisation of the recombinant tumor necrosis factors in rainbow trout, Oncorhynchus mykiss.
Developmental and comparative immunology 2003;27(9):813-22.
2003: Hong Suhee; Peddie Scott; Campos-Pérez Juan J; Zou Jun; Secombes Christopher J
The effect of intraperitoneally administered recombinant IL-1beta on immune parameters and resistance to Aeromonas salmonicida in the rainbow trout (Oncorhynchus mykiss).
Developmental and comparative immunology 2003;27(9):801-12.
2003: Stansberg Christine; Subramaniam Sumathi; Olsen Litta; Secombes Christopher J; Cunningham Charles
Cloning and characterisation of a putative ST2L homologue from Atlantic salmon (Salmo salar).
Fish & shellfish immunology 2003;15(3):211-24.
2003: Zou Jun; Clark Melody S; Secombes Chris J
Characterisation, expression and promoter analysis of an interleukin 10 homologue in the puffer fish, Fugu rubripes.
Immunogenetics 2003;55(5):325-35.
2003: Lindenstrøm T; Buchmann K; Secombes C J
Gyrodactylus derjavini infection elicits IL-1beta expression in rainbow trout skin.
Fish & shellfish immunology 2003;15(2):107-15.
2003: McLauchlan P E; Collet B; Ingerslev E; Secombes C J; Lorenzen N; Ellis A E
DNA vaccination against viral haemorrhagic septicaemia (VHS) in rainbow trout: size, dose, route of injection and duration of protection-early protection correlates with Mx expression.
Fish & shellfish immunology 2003;15(1):39-50.
2003: Scapigliati G; Meloni S; Buonocore F; Bossù P; Prugnoli D; Secombes C J
Immunopurification of B lymphocytes from sea bass Dicentrarchus labrax (L.).
Marine biotechnology (New York, N.Y.) 2003;5(3):214-21.
2003: Tafalla C; Aranguren R; Secombes C J; Castrillo J L; Novoa B; Figueras A
Molecular characterisation of sea bream (Sparus aurata) transforming growth factor beta1.
Fish & shellfish immunology 2003;14(5):405-21.
2003: Buonocore Francesco; Prugnoli Daniela; Falasca Cinzia; Secombes Christopher J; Scapigliati Giuseppe
Peculiar gene organisation and incomplete splicing of sea bass (Dicentrarchus labrax L) interleukin-1beta.
Cytokine 2003;21(6):257-64.
2003: Collet Bertrand; Hovens Guido C J; Mazzoni David; Hirono Ikuo; Aoki Takashi; Secombes Christopher J
Cloning and expression analysis of rainbow trout Oncorhynchus mykiss interferon regulatory factor 1 and 2 (IRF-1 and IRF-2).
Developmental and comparative immunology 2003;27(2):111-26.
2003: Holland J W; Gould C R W; Jones C S; Noble L R; Secombes C J
The expression of immune-regulatory genes in rainbow trout, Oncorhynchus mykiss, during a natural outbreak of proliferative kidney disease (PKD).
Parasitology 2003;126 Suppl():S95-102.
2002: Bird Steve; Zou Jun; Wang Tiehui; Munday Barry; Cunningham Charlie; Secombes Chris J
Evolution of interleukin-1beta.
Cytokine & growth factor reviews 2002;13(6):483-502.
2002: Laing Kerry J; Bols Niels; Secombes Christopher J
A CXC chemokine sequence isolated from the rainbow trout Oncorhynchus mykiss resembles the closely related interferon-gamma-inducible chemokines CXCL9, CXCL10 and CXCL11.
European cytokine network 2002;13(4):462-73.
2002: Holland J W; Pottinger T G; Secombes C J
Recombinant interleukin-1 beta activates the hypothalamic-pituitary-interrenal axis in rainbow trout, Oncorhynchus mykiss.
The Journal of endocrinology 2002;175(1):261-7.
2002: Jones Catherine S; Lockyer Anne E; Verspoor Eric; Secombes Christopher J; Noble Leslie R
Towards selective breeding of Atlantic salmon for sea louse resistance: approaches to identify trait markers.
Pest management science 2002;58(6):559-68.
2002: Laing Kerry J; Zou Jun J; Wang Tiehui; Bols Niels; Hirono Ikuo; Aoki Takashi; Secombes Christopher J
Identification and analysis of an interleukin 8-like molecule in rainbow trout Oncorhynchus mykiss.
Developmental and comparative immunology 2002;26(5):433-44.
2002: Subramaniam Sumathi; Stansberg Christine; Olsen Litta; Zou Jun; Secombes Christopher J; Cunningham Charles
Cloning of a Salmo salar interleukin-1 receptor-like cDNA.
Developmental and comparative immunology 2002;26(5):415-31.
2002: Collet Bertrand; Secombes Christopher J
Type I-interferon signalling in fish.
Fish & shellfish immunology 2002;12(5):389-97.
2002: Wang Tiehui; Zou Jun; Cunningham Charles; Secombes Christopher J
Cloning and functional characterisation of the interleukin-1 beta 1 promoter of rainbow trout (Oncorhynchus mykiss).
Biochimica et biophysica acta 2002;1575(1-3):108-16.
2002: Peddie Scott; Zou Jun; Secombes Christopher J
Immunostimulation in the rainbow trout (Oncorhynchus mykiss) following intraperitoneal administration of Ergosan.
Veterinary immunology and immunopathology 2002;86(1-2):101-13.
2002: Bird Steve; Wang Tiehui; Zou Jun; Cunningham Charlie; Secombes Chris J
The first cytokine sequence within cartilaginous fish: IL-1 beta in the small spotted catshark (Scyliorhinus canicula).
Journal of immunology (Baltimore, Md. : 1950) 2002;168(7):3329-40.
2002: Zou J; Wang T; Hirono I; Aoki T; Inagawa H; Honda T; Soma G-I; Ototake M; Nakanishi T; Ellis A E; Secombes C J
Differential expression of two tumor necrosis factor genes in rainbow trout, Oncorhynchus mykiss.
Developmental and comparative immunology 2002;26(2):161-72.
2002: Scapigliati G; Romano N; Buonocore F; Picchietti S; Baldassini M R; Prugnoli D; Galice A; Meloni S; Secombes C J; Mazzini M; Abelli L
The immune system of sea bass, Dicentrarchus labrax, reared in aquaculture.
Developmental and comparative immunology 2002;26(2):151-60.
2001: Cupit P M; Lorenzen N; Strachan G; Kemp G J; Secombes C J; Cunningham C
Neutralisation and binding of VHS virus by monovalent antibody fragments.
Virus research 2001;81(1-2):47-56.
2001: Scapigliati G; Buonocore F; Bird S; Zou J; Pelegrin P; Falasca C; Prugnoli D; Secombes C J
Phylogeny of cytokines: molecular cloning and expression analysis of sea bass Dicentrarchus labrax interleukin-1beta.
Fish & shellfish immunology 2001;11(8):711-26.
2001: Peddie S; Zou J; Cunningham C; Secombes C J
Rainbow trout (Oncorhynchus mykiss) recombinant IL-1beta and derived peptides induce migration of head-kidney leucocytes in vitro.
Fish & shellfish immunology 2001;11(8):697-709.
2001: Jørgensen J B; Zou J; Johansen A; Secombes C J
Immunostimulatory CpG oligodeoxynucleotides stimulate expression of IL-1beta and interferon-like cytokines in rainbow trout macrophages via a chloroquine-sensitive mechanism.
Fish & shellfish immunology 2001;11(8):673-82.
2001: Secombes C J; Wang T; Hong S; Peddie S; Crampe M; Laing K J; Cunningham C; Zou J
Cytokines and innate immunity of fish.
Developmental and comparative immunology 2001;25(8-9):713-23.
2001: Wang T; Ward M; Grabowski P; Secombes C J
Molecular cloning, gene organization and expression of rainbow trout (Oncorhynchus mykiss) inducible nitric oxide synthase (iNOS) gene.
The Biochemical journal 2001;358(Pt 3):747-55.
2001: Lockyer A E; Jones C S; Noble L R; Verspoor E; Holland J; Secombes C J
Isolation and characterisation of a putative interleukin 13 receptor a2 sequence from rainbow trout (Oncorhynchus mykiss).
Fish & shellfish immunology 2001;11(6):541-6.
2001: Hong S; Zou J; Crampe M; Peddie S; Scapigliati G; Bols N; Cunningham C; Secombes C J
The production and bioactivity of rainbow trout (Oncorhynchus mykiss) recombinant IL-1 beta.
Veterinary immunology and immunopathology 2001;81(1-2):1-14.
2001: Stafford J L; McLauchlan P E; Secombes C J; Ellis A E; Belosevic M
Generation of primary monocyte-like cultures from rainbow trout head kidney leukocytes.
Developmental and comparative immunology 2001;25(5-6):447-59.
2001: Laing K J; Holland J; Bonilla S; Cunningham C; Secombes C J
Cloning and sequencing of caspase 6 in rainbow trout, Oncorhynchus mykiss, and analysis of its expression under conditions known to induce apoptosis.
Developmental and comparative immunology 2001;25(4):303-12.
2001: Wang T; Secombes C J
Cloning and expression of a putative common cytokine receptor gamma chain (gammaC) gene in rainbow trout (Oncorhynchus mykiss).
Fish & shellfish immunology 2001;11(3):233-44.
2001: Collet B; Secombes C J
The rainbow trout (Oncorhynchus mykiss) Mx1 promoter. Structural and functional characterization.
European journal of biochemistry / FEBS 2001;268(6):1577-84.
2001: Laing K J; Wang T; Zou J; Holland J; Hong S; Bols N; Hirono I; Aoki T; Secombes C J
Cloning and expression analysis of rainbow trout Oncorhynchus mykiss tumour necrosis factor-alpha.
European journal of biochemistry / FEBS 2001;268(5):1315-22.
2001: Secombes C J; Bird S; Hong S; Laing K J; Zou J
Phylogeny of vertebrate cytokines.
Advances in experimental medicine and biology 2001;484():89-94.
2000: Lorenzen N; Cupit P M; Einer-Jensen K; Lorenzen E; Ahrens P; Secombes C J; Cunningham C
Immunoprophylaxis in fish by injection of mouse antibody genes.
Nature biotechnology 2000;18(11):1177-80.
2000: Henry M A; Secombes C J
The A-layer influences the susceptibility of Aeromonas salmonicida to antibacterial peptides.
Fish & shellfish immunology 2000;10(7):637-42.
2000: Pleguezuelos O; Zou J; Cunningham C; Secombes C J
Cloning, sequencing, and analysis of expression of a second IL-1beta gene in rainbow trout (Oncorhynchus mykiss).
Immunogenetics 2000;51(12):1002-11.
2000: Scapigliati G; Bird S; Secombes C J
Invertebrate and fish cytokines.
European cytokine network 2000;11(3):354-61.
2000: Zou J; Holland J; Pleguezuelos O; Cunningham C; Secombes C J
Factors influencing the expression of interleukin-1 beta in cultured rainbow trout (Oncorhynchus mykiss) leucocytes.
Developmental and comparative immunology 2000;24(6-7):575-82.
2000: Scapigliati G; Romano N; Abelli L; Meloni S; Ficca A G; Buonocore F; Bird S; Secombes C J
Immunopurification of T-cells from sea bass Dicentrarchus labrax (L.).
Fish & shellfish immunology 2000;10(4):329-41.
2000: Laing K J; Cunningham C; Secombes C J
Genes for three different isoforms of transforming growth factor-beta are present in plaice (Pleuronectes platessa) DNA.
Fish & shellfish immunology 2000;10(3):261-71.
2000: Zou J; Bird S; Minter R; Horton J; Cunningham C; Secombes C J
Molecular cloning of the gene for interleukin-1beta from Xenopus laevis and analysis of expression in vivo and in vitro.
Immunogenetics 2000;51(4-5):332-8.
2000: Secombes C J; Pilström L
Evolution of adaptive immunity.
Biologist (London, England) 2000;47(1):44-8.
2000: Lorenzen N; Cupit P M; Secombes C J; Cunningham C
Three monoclonal antibodies to the VHS virus glycoprotein: comparison of reactivity in relation to differences in immunoglobulin variable domain gene sequences.
Fish & shellfish immunology 2000;10(2):129-42.
2000: Campos-Perez J J; Ward M; Grabowski P S; Ellis A E; Secombes C J
The gills are an important site of iNOS expression in rainbow trout Oncorhynchus mykiss after challenge with the gram-positive pathogen Renibacterium salmoninarum.
Immunology 2000;99(1):153-61.
1999: Laing K J; Pilström L; Cunningham C; Secombes C J
TGF-beta3 exists in bony fish.
Veterinary immunology and immunopathology 1999;72(1-2):45-53.
1999: Zou J; Grabowski P S; Cunningham C; Secombes C J
Molecular cloning of interleukin 1beta from rainbow trout Oncorhynchus mykiss reveals no evidence of an ice cut site.
Cytokine 1999;11(8):552-60.
1999: Daniels G D; Zou J; Charlemagne J; Partula S; Cunningham C; Secombes C J
Cloning of two chemokine receptor homologs (CXC-R4 and CC-R7) in rainbow trout Oncorhynchus mykiss.
Journal of leukocyte biology 1999;65(5):684-90.
1999: Zou J; Neumann N F; Holland J W; Belosevic M; Cunningham C; Secombes C J; Rowley A F
Fish macrophages express a cyclo-oxygenase-2 homologue after activation.
The Biochemical journal 1999;340 ( Pt 1)():153-9.
1999: Daniels G D; Secombes C J
Genomic organisation of rainbow trout, Oncorhynchus mykiss TGF-beta.
Developmental and comparative immunology 1999;23(2):139-47.
1999: Zou J; Cunningham C; Secombes C J
The rainbow trout Oncorhynchus mykiss interleukin-1 beta gene has a differ organization to mammals and undergoes incomplete splicing.
European journal of biochemistry / FEBS 1999;259(3):901-8.
1999: Laing K J; Hardie L J; Aartsen W; Grabowski P S; Secombes C J
Expression of an inducible nitric oxide synthase gene in rainbow trout Oncorhynchus mykiss.
Developmental and comparative immunology 1999;23(1):71-85.
1998: Secombes C; Zou J; Daniels G; Cunningham C; Koussounadis A; Kemp G
Rainbow trout cytokine and cytokine receptor genes.
Immunological reviews 1998;166():333-40.
1998: Hardie L J; Laing K J; Daniels G D; Grabowski P S; Cunningham C; Secombes C J
Isolation of the first piscine transforming growth factor beta gene: analysis reveals tissue specific expression and a potential regulatory sequence in rainbow trout (Oncorhynchus mykiss).
Cytokine 1998;10(8):555-63.
1998: Marsden M J; Vaughan L M; Fitzpatrick R M; Foster T J; Secombes C J
Potency testing of a live, genetically attenuated vaccine for salmonids.
Vaccine 1998;16(11-12):1087-94.
1998: Hamdani S H; McMillan D N; Pettersen E F; Wergeland H; Endresen C; Ellis A E; Secombes C J
Isolation of rainbow trout neutrophils with an anti-granulocyte monoclonal antibody.
Veterinary immunology and immunopathology 1998;63(4):369-80.
1997: Davidson G A; Lin S H; Secombes C J; Ellis A E
Detection of specific and 'constitutive' antibody secreting cells in the gills, head kidney and peripheral blood leucocytes of dab (Limanda limanda).
Veterinary immunology and immunopathology 1997;58(3-4):363-74.
1997: Bowden L A; Rainger G E; Holland J W; Knight J; Secombes C J; Rowley A F
Generation and characterisation of monoclonal antibodies against rainbow trout, Oncorhynchus mykiss, leucocytes.
Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology 1997;117(3):291-8.
1996: Riley E M; Young S C; Secombes C J
Immunisation of rainbow trout Oncorhynchus mykiss with a multiple antigen peptide system (MAPS).
Veterinary immunology and immunopathology 1996;55(1-3):243-53.
1996: Marsden M J; Vaughan L M; Foster T J; Secombes C J
A live (delta aroA) Aeromonas salmonicida vaccine for furunculosis preferentially stimulates T-cell responses relative to B-cell responses in rainbow trout (Oncorhynchus mykiss).
Infection and immunity 1996;64(9):3863-9.
1996: Laing K J; Grabowski P S; Belosevic M; Secombes C J
A partial sequence for nitric oxide synthase from a goldfish (Carassius auratus) macrophage cell line.
Immunology and cell biology 1996;74(4):374-9.
1996: Novoa B; Figueras A; Secombes C J
Effects of in vitro addition of infectious pancreatic necrosis virus (IPNV) on rainbow trout Oncorhynchus mykiss leucocyte responses.
Veterinary immunology and immunopathology 1996;51(3-4):365-76.
1996: Novoa B; Figueras A; Ashton I; Secombes C J
In vitro studies on the regulation of rainbow trout (Oncorhynchus mykiss) macrophage respiratory burst activity.
Developmental and comparative immunology 1996;20(3):207-16.
1996: Bell J G; Ashton I; Secombes C J; Weitzel B R; Dick J R; Sargent J R
Dietary lipid affects phospholipid fatty acid compositions, eicosanoid production and immune function in Atlantic salmon (Salmo salar).
Prostaglandins, leukotrienes, and essential fatty acids 1996;54(3):173-82.
1995: Tahir A; Secombes C J
The effects of diesel oil-based drilling mud extracts on immune responses of rainbow trout.
Archives of environmental contamination and toxicology 1995;29(1):27-32.
1995: Jang S I; Hardie L J; Secombes C J
Elevation of rainbow trout Oncorhynchus mykiss macrophage respiratory burst activity with macrophage-derived supernatants.
Journal of leukocyte biology 1995;57(6):943-7.
1994: Ashton I; Clements K; Barrow S E; Secombes C J; Rowley A F
Effects of dietary fatty acids on eicosanoid-generating capacity, fatty acid composition and chemotactic activity of rainbow trout (Oncorhynchus mykiss) leucocytes.
Biochimica et biophysica acta 1994;1214(3):253-62.
1994: Secombes C J; Clements K; Ashton I; Rowley A F
The effect of eicosanoids on rainbow trout, Oncorhynchus mykiss, leucocyte proliferation.
Veterinary immunology and immunopathology 1994;42(3-4):367-78.
1994: Marsden M J; Cox D; Secombes C J
Antigen-induced release of macrophage activating factor from rainbow trout Oncorhynchus mykiss leucocytes.
Veterinary immunology and immunopathology 1994;42(2):199-208.
1994: Bowden L A; Weitzel B; Ashton I P; Secombes C J; Restall C J; Walton T J; Rowley A F
Effect of dietary cholesterol on membrane properties and immune functions in rainbow trout.
Biochemical Society transactions 1994;22(3):339S.
1994: Jang S I; Hardie L J; Secombes C J
Effects of transforming growth factor beta 1 on rainbow trout Oncorhynchus mykiss macrophage respiratory burst activity.
Developmental and comparative immunology 1994;18(4):315-23.
1994: Hardie L J; Chappell L H; Secombes C J
Human tumor necrosis factor alpha influences rainbow trout Oncorhynchus mykiss leucocyte responses.
Veterinary immunology and immunopathology 1994;40(1):73-84.
1994: Hardie L J; Fletcher T C; Secombes C J
Effect of temperature on macrophage activation and the production of macrophage activating factor by rainbow trout (Oncorhynchus mykiss) leucocytes.
Developmental and comparative immunology 1994;18(1):57-66.
1993: Davidson G A; Ellis A E; Secombes C J
Route of immunization influences the generation of antibody secreting cells in the gut of rainbow trout (Oncorhynchus mykiss).
Developmental and comparative immunology 1993;17(4):373-6.
1992: Secombes C J; Cross A R; Sharp G J; Garcia R
NADPH oxidase-like activity in rainbow trout Oncorhynchus mykiss (Walbaum) macrophages.
Developmental and comparative immunology 1992;16(5):405-13.
1992: Sharp G J; Pike A W; Secombes C J
Sequential development of the immune response in rainbow trout [Oncorhynchus mykiss (Walbaum, 1792)] to experimental plerocercoid infections of Diphyllobothrium dendriticum (Nitzsch, 1824).
Parasitology 1992;104 Pt 1():169-78.
1992: Sharp G J; Pettitt T R; Rowley A F; Secombes C J
Lipoxin-induced migration of fish leukocytes.
Journal of leukocyte biology 1992;51(2):140-5.
1991: Whyte S K; Secombes C J; Chappell L H
Studies on the infectivity of Diplostomum spathaceum in rainbow trout (Oncorhynchus mykiss).
Journal of helminthology 1991;65(3):169-78.
1991: Pettitt T R; Rowley A F; Barrow S E; Mallet A I; Secombes C J
Synthesis of lipoxins and other lipoxygenase products by macrophages from the rainbow trout, Oncorhynchus mykiss.
The Journal of biological chemistry 1991;266(14):8720-6.
1991: Rowley A F; Pettitt T R; Secombes C J; Sharp G J; Barrow S E; Mallet A I
Generation and biological activities of lipoxins in the rainbow trout--an overview.
Advances in prostaglandin, thromboxane, and leukotriene research 1991;21B():557-60.
1991: Sharp G J; Pike A W; Secombes C J
Leucocyte migration in rainbow trout (Oncorhynchus mykiss [Walbaum]): optimization of migration conditions and responses to host and pathogen (Diphyllobothrium dendriticum [Nitzsch]) derived chemoattractants.
Developmental and comparative immunology 1991;15(4):295-305.
1991: Secombes C J; Fletcher T C; O'Flynn J A; Costello M J; Stagg R; Houlihan D F
Immunocompetence as a measure of the biological effects of sewage sludge pollution in fish.
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology 1991;100(1-2):133-6.
1990: Sharp G J; Secombes C J; Pike A W
The laboratory maintenance of Diphyllobothrium dendriticum (Nitzsch, 1824).
Parasitology 1990;101 Pt 1():153-61.
1990: Graham S; Secombes C J
Cellular requirements for lymphokine secretion by rainbow trout Salmo gairdneri leucocytes.
Developmental and comparative immunology 1990;14(1):59-68.
1989: Pettitt T R; Rowley A F; Secombes C J
Lipoxins are major lipoxygenase products of rainbow trout macrophages.
FEBS letters 1989;259(1):168-70.
1988: Graham S; Secombes C J
The production of a macrophage-activating factor from rainbow trout Salmo gairdneri leucocytes.
Immunology 1988;65(2):293-7.
1988: Secombes C J; Chung S; Jeffries A H
Superoxide anion production by rainbow trout macrophages detected by the reduction of ferricytochrome C.
Developmental and comparative immunology 1988;12(1):201-6.
1987: Secombes C J
Lymphokine-release from rainbow trout leucocytes stimulated with concanavalin A. Effects upon macrophage spreading and adherence.
Developmental and comparative immunology 1987;11(3):513-20.
1982: Secombes C J; Manning M J; Ellis A E
Localization of immune complexes and heat-aggregated immunoglobulin in the carp Cyprinus carpio L.
Immunology 1982;47(1):101-5.
1982: Secombes C J; Manning M J; Ellis A E
The effect of primary and secondary immunization on the lymphoid tissues of the carp, Cyprinus carpio L.
The Journal of experimental zoology 1982;220(3):277-87.

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