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John Sedat
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49
Agard, David
11
marshall, wallace
8
Dernburg, Abby
6
Belmont, Andrew
5
Braunfeld, Michael
5
Paddy, Michael
5
Fung, Jennifer
5
Gruenbaum, Yosef
4
Straight, Aaron
4
Weiner, Orion
4
Gustafsson, Mats
4
Carlton, Peter
4
Cande, Zacheus
4
Alberts, Bruce
3
Bourne, Henry
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All Publications
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2009: Zheng Shawn Q; Matsuda Atsushi; Braunfeld Michael B; Sedat John W; Agard David A
Dual-axis target mapping and automated sequential acquisition of dual-axis EM tomographic data.
Journal of structural biology 2009;168(2):323-31.
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2008: Chang Henry H; Falick Arnold M; Carlton Peter M; Sedat John W; DeRisi Joseph L; Marletta Michael A
N-terminal processing of proteins exported by malaria parasites.
Molecular and biochemical parasitology 2008;160(2):107-15.
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2008: Schermelleh Lothar; Carlton Peter M; Haase Sebastian; Shao Lin; Winoto Lukman; Kner Peter; Burke Brian; Cardoso M Cristina; Agard David A; Gustafsson Mats G L; Leonhardt Heinrich; Sedat John W
Subdiffraction multicolor imaging of the nuclear periphery with 3D structured illumination microscopy.
Science (New York, N.Y.) 2008;320(5881):1332-6.
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2008: Gustafsson Mats G L; Shao Lin; Carlton Peter M; Wang C J Rachel; Golubovskaya Inna N; Cande W Zacheus; Agard David A; Sedat John W
Three-dimensional resolution doubling in wide-field fluorescence microscopy by structured illumination.
Biophysical journal 2008;94(12):4957-70.
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2008: Shao Lin; Isaac Berith; Uzawa Satoru; Agard David A; Sedat John W; Gustafsson Mats G L
I5S: wide-field light microscopy with 100-nm-scale resolution in three dimensions.
Biophysical journal 2008;94(12):4971-83.
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2008: Pielage Jan; Cheng Ling; Fetter Richard D; Carlton Pete M; Sedat John W; Davis Graeme W
A presynaptic giant ankyrin stabilizes the NMJ through regulation of presynaptic microtubules and transsynaptic cell adhesion.
Neuron 2008;58(2):195-209.
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2008: Wang Xueying; Kam Zvi; Carlton Peter M; Xu Lifeng; Sedat John W; Blackburn Elizabeth H
Rapid telomere motions in live human cells analyzed by highly time-resolved microscopy.
Epigenetics & chromatin 2008;1(1):4.
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2007: König Peter; Braunfeld Michael B; Sedat John W; Agard David A
The three-dimensional structure of in vitro reconstituted Xenopus laevis chromosomes by EM tomography.
Chromosoma 2007;116(4):349-72.
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2007: Hom Erik F Y; Marchis Franck; Lee Timothy K; Haase Sebastian; Agard David A; Sedat John W
AIDA: an adaptive image deconvolution algorithm with application to multi-frame and three-dimensional data.
Journal of the Optical Society of America. A, Optics, image science, and vision 2007;24(6):1580-600.
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2007: Kam Zvi; Kner Peter; Agard David; Sedat John W
Modelling the application of adaptive optics to wide-field microscope live imaging.
Journal of microscopy 2007;226(Pt 1):33-42.
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2007: Krug Roland; Carballido-Gamio Julio; Burghardt Andrew J; Haase Sebastian; Sedat John W; Moss William C; Majumdar Sharmila
Wavelet-based characterization of vertebral trabecular bone structure from magnetic resonance images at 3 T compared with micro-computed tomographic measurements.
Magnetic resonance imaging 2007;25(3):392-8.
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2007: Zheng Shawn Q; Kollman Justin M; Braunfeld Michael B; Sedat John W; Agard David A
Automated acquisition of electron microscopic random conical tilt sets.
Journal of structural biology 2007;157(1):148-55.
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2007: Zheng Shawn Q; Keszthelyi Bettina; Branlund Eric; Lyle John M; Braunfeld Michael B; Sedat John W; Agard David A
UCSF tomography: an integrated software suite for real-time electron microscopic tomographic data collection, alignment, and reconstruction.
Journal of structural biology 2007;157(1):138-47.
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2006: Vazquez Julio; Müller Martin; Pirrotta Vincenzo; Sedat John W
The Mcp element mediates stable long-range chromosome-chromosome interactions in Drosophila.
Molecular biology of the cell 2006;17(5):2158-65.
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2005: Moss W C; Haase S; Lyle J M; Agard D A; Sedat J W
A novel 3D wavelet-based filter for visualizing features in noisy biological data.
Journal of microscopy 2005;219(Pt 2):43-9.
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2005: Harmon Brian; Sedat John
Cell-by-cell dissection of gene expression and chromosomal interactions reveals consequences of nuclear reorganization.
PLoS biology 2005;3(3):e67.
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2004: Lowenstein Michael G; Goddard Thomas D; Sedat John W
Long-range interphase chromosome organization in Drosophila: a study using color barcoded fluorescence in situ hybridization and structural clustering analysis.
Molecular biology of the cell 2004;15(12):5678-92.
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2004: Hanser B M; Gustafsson M G L; Agard D A; Sedat J W
Phase-retrieved pupil functions in wide-field fluorescence microscopy.
Journal of microscopy 2004;216(Pt 1):32-48.
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2004: Zheng Qingxiong S; Braunfeld Michael B; Sedat John W; Agard David A
An improved strategy for automated electron microscopic tomography.
Journal of structural biology 2004;147(2):91-101.
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2003: Hanser Bridget M; Gustafsson Mats G L; Agard David A; Sedat John W
Phase retrieval for high-numerical-aperture optical systems.
Optics letters 2003;28(10):801-3.
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2002: Vazquez Julio; Belmont Andrew S; Sedat John W
The dynamics of homologous chromosome pairing during male Drosophila meiosis.
Current biology : CB 2002;12(17):1473-83.
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2001: Vazquez J; Belmont A S; Sedat J W
Multiple regimes of constrained chromosome motion are regulated in the interphase Drosophila nucleus.
Current biology : CB 2001;11(16):1227-39.
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2001: Marshall W F; Marko J F; Agard D A; Sedat J W
Chromosome elasticity and mitotic polar ejection force measured in living Drosophila embryos by four-dimensional microscopy-based motion analysis.
Current biology : CB 2001;11(8):569-78.
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2001: Grogan J L; Mohrs M; Harmon B; Lacy D A; Sedat J W; Locksley R M
Early transcription and silencing of cytokine genes underlie polarization of T helper cell subsets.
Immunity 2001;14(3):205-15.
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2001: Kam Z; Hanser B; Gustafsson M G; Agard D A; Sedat J W
Computational adaptive optics for live three-dimensional biological imaging.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(7):3790-5.
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2000: Bass H W; Riera-Lizarazu O; Ananiev E V; Bordoli S J; Rines H W; Phillips R L; Sedat J W; Agard D A; Cande W Z
Evidence for the coincident initiation of homolog pairing and synapsis during the telomere-clustering (bouquet) stage of meiotic prophase.
Journal of cell science 2000;113 ( Pt 6)():1033-42.
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2000: Servant G; Weiner O D; Herzmark P; Balla T; Sedat J W; Bourne H R
Polarization of chemoattractant receptor signaling during neutrophil chemotaxis.
Science (New York, N.Y.) 2000;287(5455):1037-40.
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1999: Kalman D; Weiner O D; Goosney D L; Sedat J W; Finlay B B; Abo A; Bishop J M
Enteropathogenic E. coli acts through WASP and Arp2/3 complex to form actin pedestals.
Nature cell biology 1999;1(6):389-91.
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1999: Gustafsson M G; Agard D A; Sedat J W
I5M: 3D widefield light microscopy with better than 100 nm axial resolution.
Journal of microscopy 1999;195(Pt 1):10-6.
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1999: Weiner O D; Servant G; Welch M D; Mitchison T J; Sedat J W; Bourne H R
Spatial control of actin polymerization during neutrophil chemotaxis.
Nature cell biology 1999;1(2):75-81.
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1999: Servant G; Weiner O D; Neptune E R; Sedat J W; Bourne H R
Dynamics of a chemoattractant receptor in living neutrophils during chemotaxis.
Molecular biology of the cell 1999;10(4):1163-78.
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1999: Marshall W F; Sedat J W
Nuclear architecture.
Results and problems in cell differentiation 1999;25():283-301.
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1998: Straight A F; Sedat J W; Murray A W
Time-lapse microscopy reveals unique roles for kinesins during anaphase in budding yeast.
The Journal of cell biology 1998;143(3):687-94.
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1998: Fung J C; Marshall W F; Dernburg A; Agard D A; Sedat J W
Homologous chromosome pairing in Drosophila melanogaster proceeds through multiple independent initiations.
The Journal of cell biology 1998;141(1):5-20.
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1998: Dernburg A F; Sedat J W
Mapping three-dimensional chromosome architecture in situ.
Methods in cell biology 1998;53():187-233.
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1997: Han K F; Sedat J W; Agard D A
Practical image restoration of thick biological specimens using multiple focus levels in transmission electron microscopy.
Journal of structural biology 1997;120(3):237-44.
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1997: Marshall W F; Straight A; Marko J F; Swedlow J; Dernburg A; Belmont A; Murray A W; Agard D A; Sedat J W
Interphase chromosomes undergo constrained diffusional motion in living cells.
Current biology : CB 1997;7(12):930-9.
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1997: Oegema K; Marshall W F; Sedat J W; Alberts B M
Two proteins that cycle asynchronously between centrosomes and nuclear structures: Drosophila CP60 and CP190.
Journal of cell science 1997;110 ( Pt 14)():1573-83.
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1997: Nunnari J; Marshall W F; Straight A; Murray A; Sedat J W; Walter P
Mitochondrial transmission during mating in Saccharomyces cerevisiae is determined by mitochondrial fusion and fission and the intramitochondrial segregation of mitochondrial DNA.
Molecular biology of the cell 1997;8(7):1233-42.
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1997: Straight A F; Marshall W F; Sedat J W; Murray A W
Mitosis in living budding yeast: anaphase A but no metaphase plate.
Science (New York, N.Y.) 1997;277(5325):574-8.
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1997: Marshall W F; Fung J C; Sedat J W
Deconstructing the nucleus: global architecture from local interactions.
Current opinion in genetics & development 1997;7(2):259-63.
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1997: Bass H W; Marshall W F; Sedat J W; Agard D A; Cande W Z
Telomeres cluster de novo before the initiation of synapsis: a three-dimensional spatial analysis of telomere positions before and during meiotic prophase.
The Journal of cell biology 1997;137(1):5-18.
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1997: Kirk K E; Harmon B P; Reichardt I K; Sedat J W; Blackburn E H
Block in anaphase chromosome separation caused by a telomerase template mutation.
Science (New York, N.Y.) 1997;275(5305):1478-81.
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1996: Dernburg A F; Daily D R; Yook K J; Corbin J A; Sedat J W; Sullivan W
Selective loss of sperm bearing a compound chromosome in the Drosophila female.
Genetics 1996;143(4):1629-42.
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1996: Han K F; Gubbens A J; Sedat J W; Agard D A
Optimal strategies for imaging thick biological specimens: exit wavefront reconstruction and energy-filtered imaging.
Journal of microscopy 1996;183(Pt 2):124-32.
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1996: Dernburg A F; Sedat J W; Hawley R S
Direct evidence of a role for heterochromatin in meiotic chromosome segregation.
Cell 1996;86(1):135-46.
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1996: Marshall W F; Dernburg A F; Harmon B; Agard D A; Sedat J W
Specific interactions of chromatin with the nuclear envelope: positional determination within the nucleus in Drosophila melanogaster.
Molecular biology of the cell 1996;7(5):825-42.
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1996: Dernburg A F; Broman K W; Fung J C; Marshall W F; Philips J; Agard D A; Sedat J W
Perturbation of nuclear architecture by long-distance chromosome interactions.
Cell 1996;85(5):745-59.
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1996: Scalettar B A; Swedlow J R; Sedat J W; Agard D A
Dispersion, aberration and deconvolution in multi-wavelength fluorescence images.
Journal of microscopy 1996;182(Pt 1):50-60.
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1996: Paddy M R; Saumweber H; Agard D A; Sedat J W
Time-resolved, in vivo studies of mitotic spindle formation and nuclear lamina breakdown in Drosophila early embryos.
Journal of cell science 1996;109 ( Pt 3)():591-607.
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1996: Fung J C; Liu W; de Ruijter W J; Chen H; Abbey C K; Sedat J W; Agard D A
Toward fully automated high-resolution electron tomography.
Journal of structural biology 1996;116(1):181-9.
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1996: Chen H; Hughes D D; Chan T A; Sedat J W; Agard D A
IVE (Image Visualization Environment): a software platform for all three-dimensional microscopy applications.
Journal of structural biology 1996;116(1):56-60.
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1995: Moritz M; Braunfeld M B; Sedat J W; Alberts B; Agard D A
Microtubule nucleation by gamma-tubulin-containing rings in the centrosome.
Nature 1995;378(6557):638-40.
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1995: Urata Y; Parmelee S J; Agard D A; Sedat J W
A three-dimensional structural dissection of Drosophila polytene chromosomes.
The Journal of cell biology 1995;131(2):279-95.
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1995: Moritz M; Braunfeld M B; Fung J C; Sedat J W; Alberts B M; Agard D A
Three-dimensional structural characterization of centrosomes from early Drosophila embryos.
The Journal of cell biology 1995;130(5):1149-59.
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1995: Han K F; Sedat J W; Agard D A
Mechanism of image formation for thick biological specimens: exit wavefront reconstruction and electron energy-loss spectroscopic imaging.
Journal of microscopy 1995;178(Pt 2):107-19.
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1994: Braunfeld M B; Koster A J; Sedat J W; Agard D A
Cryo automated electron tomography: towards high-resolution reconstructions of plastic-embedded structures.
Journal of microscopy 1994;174(Pt 2):75-84.
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1994: Horowitz R A; Agard D A; Sedat J W; Woodcock C L
The three-dimensional architecture of chromatin in situ: electron tomography reveals fibers composed of a continuously variable zig-zag nucleosomal ribbon.
The Journal of cell biology 1994;125(1):1-10.
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1994: Dawe R K; Sedat J W; Agard D A; Cande W Z
Meiotic chromosome pairing in maize is associated with a novel chromatin organization.
Cell 1994;76(5):901-12.
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1993: Swedlow J R; Agard D A; Sedat J W
Chromosome structure inside the nucleus.
Current opinion in cell biology 1993;5(3):412-6.
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1993: Swedlow J R; Sedat J W; Agard D A
Multiple chromosomal populations of topoisomerase II detected in vivo by time-lapse, three-dimensional wide-field microscopy.
Cell 1993;73(1):97-108.
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1993: Hiraoka Y; Dernburg A F; Parmelee S J; Rykowski M C; Agard D A; Sedat J W
The onset of homologous chromosome pairing during Drosophila melanogaster embryogenesis.
The Journal of cell biology 1993;120(3):591-600.
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1992: Koster A J; Chen H; Sedat J W; Agard D A
Automated microscopy for electron tomography.
Ultramicroscopy 1992;46(1-4):207-27.
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1992: Paddy M R; Agard D A; Sedat J W
An extended view of nuclear lamin structure, function, and dynamics.
Seminars in cell biology 1992;3(4):255-66.
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1991: Kam Z; Minden J S; Agard D A; Sedat J W; Leptin M
Drosophila gastrulation: analysis of cell shape changes in living embryos by three-dimensional fluorescence microscopy.
Development (Cambridge, England) 1991;112(2):365-70.
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1991: Hiraoka Y; Swedlow J R; Paddy M R; Agard D A; Sedat J W
Three-dimensional multiple-wavelength fluorescence microscopy for the structural analysis of biological phenomena.
Seminars in cell biology 1991;2(3):153-65.
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1990: Hiraoka Y; Agard D A; Sedat J W
Temporal and spatial coordination of chromosome movement, spindle formation, and nuclear envelope breakdown during prometaphase in Drosophila melanogaster embryos.
The Journal of cell biology 1990;111(6 Pt 2):2815-28.
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1990: Paddy M R; Belmont A S; Saumweber H; Agard D A; Sedat J W
Interphase nuclear envelope lamins form a discontinuous network that interacts with only a fraction of the chromatin in the nuclear periphery.
Cell 1990;62(1):89-106.
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1990: Hiraoka Y; Sedat J W; Agard D A
Determination of three-dimensional imaging properties of a light microscope system. Partial confocal behavior in epifluorescence microscopy.
Biophysical journal 1990;57(2):325-33.
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1989: Hiraoka Y; Minden J S; Swedlow J R; Sedat J W; Agard D A
Focal points for chromosome condensation and decondensation revealed by three-dimensional in vivo time-lapse microscopy.
Nature 1989;342(6247):293-6.
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1989: Minden J S; Agard D A; Sedat J W; Alberts B M
Direct cell lineage analysis in Drosophila melanogaster by time-lapse, three-dimensional optical microscopy of living embryos.
The Journal of cell biology 1989;109(2):505-16.
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1989: Belmont A S; Braunfeld M B; Sedat J W; Agard D A
Large-scale chromatin structural domains within mitotic and interphase chromosomes in vivo and in vitro.
Chromosoma 1989;98(2):129-43.
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1989: Mathog D; Sedat J W
The three-dimensional organization of polytene nuclei in male Drosophila melanogaster with compound XY or ring X chromosomes.
Genetics 1989;121(2):293-311.
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1989: Shaw P J; Agard D A; Hiraoka Y; Sedat J W
Tilted view reconstruction in optical microscopy. Three-dimensional reconstruction of Drosophila melanogaster embryo nuclei.
Biophysical journal 1989;55(1):101-10.
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1989: Aikens R S; Agard D A; Sedat J W
Solid-state imagers for microscopy.
Methods in cell biology 1989;29():291-313.
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1989: Agard D A; Hiraoka Y; Shaw P; Sedat J W
Fluorescence microscopy in three dimensions.
Methods in cell biology 1989;30():353-77.
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1988: Rykowski M C; Parmelee S J; Agard D A; Sedat J W
Precise determination of the molecular limits of a polytene chromosome band: regulatory sequences for the Notch gene are in the interband.
Cell 1988;54(4):461-72.
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1988: Gruenbaum Y; Landesman Y; Drees B; Bare J W; Saumweber H; Paddy M R; Sedat J W; Smith D E; Benton B M; Fisher P A
Drosophila nuclear lamin precursor Dm0 is translated from either of two developmentally regulated mRNA species apparently encoded by a single gene.
The Journal of cell biology 1988;106(3):585-96.
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1988: Agard D A; Hiraoka Y; Sedat J W
Three-dimensional light microscopy of diploid Drosophila chromosomes.
Cell motility and the cytoskeleton 1988;10(1-2):18-27.
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1987: Hiraoka Y; Sedat J W; Agard D A
The use of a charge-coupled device for quantitative optical microscopy of biological structures.
Science (New York, N.Y.) 1987;238(4823):36-41.
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1987: Belmont A S; Sedat J W; Agard D A
A three-dimensional approach to mitotic chromosome structure: evidence for a complex hierarchical organization.
The Journal of cell biology 1987;105(1):77-92.
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1987: Hochstrasser M; Sedat J W
Three-dimensional organization of Drosophila melanogaster interphase nuclei. II. Chromosome spatial organization and gene regulation.
The Journal of cell biology 1987;104(6):1471-83.
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1987: Hochstrasser M; Sedat J W
Three-dimensional organization of Drosophila melanogaster interphase nuclei. I. Tissue-specific aspects of polytene nuclear architecture.
The Journal of cell biology 1987;104(6):1455-70.
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1986: Hochstrasser M; Mathog D; Gruenbaum Y; Saumweber H; Sedat J W
Spatial organization of chromosomes in the salivary gland nuclei of Drosophila melanogaster.
The Journal of cell biology 1986;102(1):112-23.
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1985: Mathog D; Hochstrasser M; Sedat J W
Light microscope based analysis of three-dimensional structure: applications to the study of Drosophila salivary gland nuclei. I. Data collection and analysis.
Journal of microscopy 1985;137(Pt 3):241-52.
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1984: Dequin R; Saumweber H; Sedat J W
Proteins shifting from the cytoplasm into the nuclei during early embryogenesis of Drosophila melanogaster.
Developmental biology 1984;104(1):37-48.
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1984: Mathog D; Hochstrasser M; Gruenbaum Y; Saumweber H; Sedat J
Characteristic folding pattern of polytene chromosomes in Drosophila salivary gland nuclei.
Nature 1984;308(5958):414-21.
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1984: Gruenbaum Y; Hochstrasser M; Mathog D; Saumweber H; Agard D A; Sedat J W
Spatial organization of the Drosophila nucleus: a three-dimensional cytogenetic study.
Journal of cell science. Supplement 1984;1():223-34.
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1983: Fuchs J P; Giloh H; Kuo C H; Saumweber H; Sedat J
Nuclear structure: determination of the fate of the nuclear envelope in Drosophila during mitosis using monoclonal antibodies.
Journal of cell science 1983;64():331-49.
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1983: Mitchison T J; Sedat J
Localization of antigenic determinants in whole Drosophila embryos.
Developmental biology 1983;99(1):261-4.
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1983: Agard D A; Sedat J W
Three-dimensional architecture of a polytene nucleus.
Nature 1983;302(5910):676-81.
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1982: Kuo C H; Gilon H; Blumenthal A B; Sedat J W
A library of monoclonal antibodies to nuclear proteins from Drosophila melanogaster embryos. Characterization by a cultured cell assay.
Experimental cell research 1982;142(1):141-54.
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1982: Mortin L I; Sedat J W
Structure of Drosophila polytene chromosomes. Evidence for a toroidal organization of the bands.
Journal of cell science 1982;57():73-113.
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1982: Giloh H; Sedat J W
Fluorescence microscopy: reduced photobleaching of rhodamine and fluorescein protein conjugates by n-propyl gallate.
Science (New York, N.Y.) 1982;217(4566):1252-5.
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1982: Urieli-Shoval S; Gruenbaum Y; Sedat J; Razin A
The absence of detectable methylated bases in Drosophila melanogaster DNA.
FEBS letters 1982;146(1):148-52.
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1980: Manuelidis L; Sedat J; Feder R
Soft x-ray lithographic studies of interphase chromosomes.
Annals of the New York Academy of Sciences 1980;342():304-25.
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