Username

Password

Preview

Sign-in free and Explore the Exciting World of BiomedExperts:

Over 1.500.000 Profiles
More than 1.800 Organizations worldwide
State of the Art Network Visualizations

Manage your own Profile
Locate Experts in your Country/Region
Locate Experts in your 1. and 2. Level Network
Connect to Experts Worldwide

NetworkView

Werner Seeger

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Anatomy

Living Beings

Rabbits
Mice

Disorders

Physiology

Chemicals & Drugs

Procedures

Sign-in to see full Profile

Sign-in to see all Coauthors

Publications

TOP 3
Althaus Mike; Fronius Martin; Buchäckert Yasmin; Vadász István; Clauss Wolfgang G; Seeger Werner; Motterlini Roberto; Morty Rory E
Carbon monoxide rapidly impairs alveolar fluid clearance by inhibiting epithelial sodium channels.
Kolosionek Ewa; Savai Rajkumar; Ghofrani Hossein Ardeschir; Weissmann Norbert; Guenther Andreas; Grimminger Friedrich; Seeger Werner; Banat Gamal Andre; Schermuly Ralph Theo; Pullamsetti Soni Savai
Expression and activity of phosphodiesterase isoforms during epithelial mesenchymal transition: the role of phosphodiesterase 4.
Nguyen Juliane; Reul Regina; Betz Thomas; Dayyoub Eyas; Schmehl Thomas; Gessler Tobias; Bakowsky Udo; Seeger Werner; Kissel Thomas
Nanocomposites of lung surfactant and biodegradable cationic nanoparticles improve transfection efficiency to lung cells.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of Werner Seeger (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2009: Althaus Mike; Fronius Martin; Buchäckert Yasmin; Vadász István; Clauss Wolfgang G; Seeger Werner; Motterlini Roberto; Morty Rory E
Carbon monoxide rapidly impairs alveolar fluid clearance by inhibiting epithelial sodium channels.
American journal of respiratory cell and molecular biology 2009;41(6):639-50.
2009: Kolosionek Ewa; Savai Rajkumar; Ghofrani Hossein Ardeschir; Weissmann Norbert; Guenther Andreas; Grimminger Friedrich; Seeger Werner; Banat Gamal Andre; Schermuly Ralph Theo; Pullamsetti Soni Savai
Expression and activity of phosphodiesterase isoforms during epithelial mesenchymal transition: the role of phosphodiesterase 4.
Molecular biology of the cell 2009;20(22):4751-65.
2009: Nguyen Juliane; Reul Regina; Betz Thomas; Dayyoub Eyas; Schmehl Thomas; Gessler Tobias; Bakowsky Udo; Seeger Werner; Kissel Thomas
Nanocomposites of lung surfactant and biodegradable cationic nanoparticles improve transfection efficiency to lung cells.
Journal of controlled release : official journal of the Controlled Release Society 2009;140(1):47-54.
2009: Reichenberger F; Voswinckel R; Schulz R; Mensch O; Ghofrani H A; Olschewski H; Seeger W
Noninvasive detection of early pulmonary vascular dysfunction in scleroderma.
Respiratory medicine 2009;103(11):1713-8.
2009: Grandel Ulrich; Heygster Diana; Sibelius Ulf; Fink Ludger; Sigel Stefanie; Seeger Werner; Grimminger Friedrich; Hattar Katja
Amplification of lipopolysaccharide-induced cytokine synthesis in non-small cell lung cancer/neutrophil cocultures.
Molecular cancer research : MCR 2009;7(10):1729-35.
2009: Weissmann Norbert; Hackemack Sascha; Dahal Bhola Kumar; Pullamsetti Soni Savai; Savai Rajkumar; Mittal Manish; Fuchs Beate; Medebach Thomas; Dumitrascu Rio; Eickels Martin van; Ghofrani Hossein Ardeschir; Seeger Werner; Grimminger Friedrich; Schermuly Ralph Theo
The soluble guanylate cyclase activator HMR1766 reverses hypoxia-induced experimental pulmonary hypertension in mice.
American journal of physiology. Lung cellular and molecular physiology 2009;297(4):L658-65.
2009: Voswinckel R; Reichenberger F; Gall H; Seeger W; Grimminger F; Ghofrani H A
[Therapy of pulmonary arterial hypertension]
Der Internist 2009;50(9):1101-2, 1104-9.
2009: Roderfeld Martin; Rath Timo; Schulz Richard; Seeger Werner; Tschuschner Annette; Graf Jürgen; Roeb Elke
Serum matrix metalloproteinases in adult CF patients: Relation to pulmonary exacerbation.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society 2009;8(5):338-47.
2009: Cakarova Lidija; Marsh Leigh M; Wilhelm Jochen; Mayer Konstantin; Grimminger Friedrich; Seeger Werner; Lohmeyer Juergen; Herold Susanne
Macrophage tumor necrosis factor-alpha induces epithelial expression of granulocyte-macrophage colony-stimulating factor: impact on alveolar epithelial repair.
American journal of respiratory and critical care medicine 2009;180(6):521-32.
2009: Kleemann Elke; Jekel Norman; Dailey Lea Ann; Roesler Susanne; Fink Ludger; Weissmann Norbert; Schermuly Ralph; Gessler Tobias; Schmehl Thomas; Roberts Clive J; Seeger Werner; Kissel Thomas
Enhanced gene expression and reduced toxicity in mice using polyplexes of low-molecular-weight poly(ethylene imine) for pulmonary gene delivery.
Journal of drug targeting 2009;17(8):638-51.
2009: Roth Markus; Rupp Markus; Hofmann Simone; Mittal Manish; Fuchs Beate; Sommer Natascha; Parajuli Nirmal; Quanz Karin; Schubert Dominic; Dony Eva; Schermuly Ralph Theo; Ghofrani Hossein Ardeschir; Sausbier Ulrike; Rutschmann Katrin; Wilhelm Sarah; Seeger Werner; Ruth Peter; Grimminger Friedrich; Sausbier Matthias; Weissmann Norbert
Heme oxygenase-2 and large-conductance Ca2+-activated K+ channels: lung vascular effects of hypoxia.
American journal of respiratory and critical care medicine 2009;180(4):353-64.
2009: McLaughlin Vallerie V; Badesch David B; Delcroix Marion; Fleming Thomas R; Gaine Sean P; Galiè Nazzareno; Gibbs J Simon R; Kim Nick H; Oudiz Ronald J; Peacock Andrew; Provencher Steeve; Sitbon Olivier; Tapson Victor F; Seeger Werner
End points and clinical trial design in pulmonary arterial hypertension.
Journal of the American College of Cardiology 2009;54(1 Suppl):S97-107.
2009: Laumanns Isabel P; Fink Ludger; Wilhelm Jochen; Wolff Jens-C; Mitnacht-Kraus Rita; Graef-Hoechst Sabine; Stein Maria M; Bohle Rainer M; Klepetko Walter; Hoda Mir A R; Schermuly Ralph T; Grimminger Friedrich; Seeger Werner; Voswinckel Robert
The noncanonical WNT pathway is operative in idiopathic pulmonary arterial hypertension.
American journal of respiratory cell and molecular biology 2009;40(6):683-91.
2009: Königshoff Melanie; Kramer Monika; Balsara Nisha; Wilhelm Jochen; Amarie Oana Veronica; Jahn Andreas; Rose Frank; Fink Ludger; Seeger Werner; Schaefer Liliana; Günther Andreas; Eickelberg Oliver
WNT1-inducible signaling protein-1 mediates pulmonary fibrosis in mice and is upregulated in humans with idiopathic pulmonary fibrosis.
The Journal of clinical investigation 2009;119(4):772-87.
2009: Woyda K; Koebrich S; Reiss I; Rudloff S; Pullamsetti S S; Rühlmann A; Weissmann N; Ghofrani H A; Günther A; Seeger W; Grimminger F; Morty R E; Schermuly R T
Inhibition of phosphodiesterase 4 enhances lung alveolarisation in neonatal mice exposed to hyperoxia.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2009;33(4):861-70.
2009: Reichenberger F; Seeger W; Nitschmann S
[Therapy of mild, but symptomatic pulmonary hypertension]
Der Internist 2009;50(3):374-6.
2009: Marsh Leigh M; Cakarova Lidija; Kwapiszewska Grazyna; von Wulffen Werner; Herold Susanne; Seeger Werner; Lohmeyer Juergen
Surface expression of CD74 by type II alveolar epithelial cells: a potential mechanism for macrophage migration inhibitory factor-induced epithelial repair.
American journal of physiology. Lung cellular and molecular physiology 2009;296(3):L442-52.
2009: Mayer Konstantin; Kiessling Almuth; Ott Juliane; Schaefer Martina Barbara; Hecker Matthias; Henneke Ingrid; Schulz Richard; Günther Andreas; Wang Jingdong; Wu Lijun; Roth Joachim; Seeger Werner; Kang Jing X
Acute lung injury is reduced in fat-1 mice endogenously synthesizing n-3 fatty acids.
American journal of respiratory and critical care medicine 2009;179(6):474-83.
2009: Egemnazarov Bakytbek; Sydykov Akylbek; Schermuly Ralph T; Weissmann Norbert; Stasch Johannes-Peter; Sarybaev Akpai S; Seeger Werner; Grimminger Friedrich; Ghofrani Hossein A
Novel soluble guanylyl cyclase stimulator BAY 41-2272 attenuates ischemia-reperfusion-induced lung injury.
American journal of physiology. Lung cellular and molecular physiology 2009;296(3):L462-9.
2009: Kamlah F; Eul B G; Li S; Lang N; Marsh L M; Seeger W; Grimminger F; Rose F; Hänze J
Intravenous injection of siRNA directed against hypoxia-inducible factors prolongs survival in a Lewis lung carcinoma cancer model.
Cancer gene therapy 2009;16(3):195-205.
2009: Voswinckel Robert; Reichenberger Frank; Gall Henning; Schmehl Thomas; Gessler Tobias; Schermuly Ralph Theo; Grimminger Friedrich; Rubin Lewis J; Seeger Werner; Ghofrani Hossein A; Olschewski Horst
Metered dose inhaler delivery of treprostinil for the treatment of pulmonary hypertension.
Pulmonary pharmacology & therapeutics 2009;22(1):50-6.
2009: Beck-Broichsitter Moritz; Gauss Julia; Packhaeuser Claudia B; Lahnstein Kerstin; Schmehl Thomas; Seeger Werner; Kissel Thomas; Gessler Tobias
Pulmonary drug delivery with aerosolizable nanoparticles in an ex vivo lung model.
International journal of pharmaceutics 2009;367(1-2):169-78.
2009: Markart Philipp; Luboeinski Thomas; Korfei Martina; Schmidt Reinhold; Wygrecka Malgorzata; Mahavadi Poornima; Mayer Konstantin; Wilhelm Jochen; Seeger Werner; Guenther Andreas; Ruppert Clemens
Alveolar oxidative stress is associated with elevated levels of nonenzymatic low-molecular-weight antioxidants in patients with different forms of chronic fibrosing interstitial lung diseases.
Antioxidants & redox signaling 2009;11(2):227-40.
2009: Zaslona Zbigniew; Wilhelm Jochen; Cakarova Lidija; Marsh Leigh M; Seeger Werner; Lohmeyer Jürgen; von Wulffen Werner
Transcriptome profiling of primary murine monocytes, lung macrophages and lung dendritic cells reveals a distinct expression of genes involved in cell trafficking.
Respiratory research 2009;10():2.
2008: Ruppert Clemens; Mahavadi Poornima; Wygrecka Malgorzata; Weaver Timothy E; Magdolen Viktor; Idell Steven; Preissner Klaus T; Seeger Werner; Günther Andreas; Markart Philipp
Recombinant production of a hybrid plasminogen activator composed of surfactant protein B and low-molecular-weight urokinase.
Thrombosis and haemostasis 2008;100(6):1185-92.
2008: Sommer N; Dietrich A; Schermuly R T; Ghofrani H A; Gudermann T; Schulz R; Seeger W; Grimminger F; Weissmann N
Regulation of hypoxic pulmonary vasoconstriction: basic mechanisms.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2008;32(6):1639-51.
2008: Schaefer M B; Pose A; Ott J; Hecker M; Behnk A; Schulz R; Weissmann N; Günther A; Seeger W; Mayer K
Peroxisome proliferator-activated receptor-alpha reduces inflammation and vascular leakage in a murine model of acute lung injury.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2008;32(5):1344-53.
2008: Kiss Ladislau; Bier Jens; Röder Yasmin; Weissmann Norbert; Grimminger Friedrich; Seeger Werner
Direct and simultaneous profiling of epoxyeicosatrienoic acid enantiomers by capillary tandem column chiral-phase liquid chromatography with dual online photodiode array and tandem mass spectrometric detection.
Analytical and bioanalytical chemistry 2008;392(4):717-26.
2008: Voswinckel Robert; Reichenberger Frank; Enke Beate; Kreckel Andre; Krick Stefanie; Gall Henning; Schermuly Ralph Theo; Grimminger Friedrich; Rubin Lewis J; Olschewski Horst; Seeger Werner; Ghofrani Hossein A
Acute effects of the combination of sildenafil and inhaled treprostinil on haemodynamics and gas exchange in pulmonary hypertension.
Pulmonary pharmacology & therapeutics 2008;21(5):824-32.
2008: Korfei Martina; Ruppert Clemens; Mahavadi Poornima; Henneke Ingrid; Markart Philipp; Koch Miriam; Lang Gyoergy; Fink Ludger; Bohle Rainer-Maria; Seeger Werner; Weaver Timothy E; Guenther Andreas
Epithelial endoplasmic reticulum stress and apoptosis in sporadic idiopathic pulmonary fibrosis.
American journal of respiratory and critical care medicine 2008;178(8):838-46.
2008: Li Shu; Tabar Sarvenaz Shafiei; Malec Viktor; Eul Bastian G; Klepetko Walter; Weissmann Norbert; Grimminger Friedrich; Seeger Werner; Rose Frank; Hänze Jörg
NOX4 regulates ROS levels under normoxic and hypoxic conditions, triggers proliferation, and inhibits apoptosis in pulmonary artery adventitial fibroblasts.
Antioxidants & redox signaling 2008;10(10):1687-98.
2008: Sevilla-Pérez J; Königshoff M; Kwapiszewska G; Amarie O V; Seeger W; Weissmann N; Schermuly R T; Morty R E; Eickelberg O
Shroom expression is attenuated in pulmonary arterial hypertension.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2008;32(4):871-80.
2008: Schermuly R T; Stasch J-P; Pullamsetti S S; Middendorff R; Müller D; Schlüter K-D; Dingendorf A; Hackemack S; Kolosionek E; Kaulen C; Dumitrascu R; Weissmann N; Mittendorf J; Klepetko W; Seeger W; Ghofrani H A; Grimminger F
Expression and function of soluble guanylate cyclase in pulmonary arterial hypertension.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2008;32(4):881-91.
2008: Kwapiszewska Grazyna; Wygrecka Malgorzata; Marsh Leigh M; Schmitt Sigrid; Trösser Roger; Wilhelm Jochen; Helmus Katja; Eul Bastian; Zakrzewicz Anna; Ghofrani Hossein A; Schermuly Ralph T; Bohle Rainer M; Grimminger Friedrich; Seeger Werner; Eickelberg Oliver; Fink Ludger; Weissmann Norbert
Fhl-1, a new key protein in pulmonary hypertension.
Circulation 2008;118(11):1183-94.
2008: Lis Stefanie; Krieger Stephan; Hennig Dorothee; Röder Christian; Kirsch Peter; Seeger Werner; Gallhofer Bernd; Schulz Richard
Executive functions and cognitive subprocesses in patients with obstructive sleep apnoea.
Journal of sleep research 2008;17(3):271-80.
2008: Ahlbrecht Katrin; Schmitz Judith; Seay Ulrike; Schwarz Christine; Mittnacht-Kraus Rita; Gaumann Andreas; Haberberger Rainer V; Herold Susanne; Breier Georg; Grimminger Friedrich; Seeger Werner; Voswinckel Robert
Spatiotemporal expression of flk-1 in pulmonary epithelial cells during lung development.
American journal of respiratory cell and molecular biology 2008;39(2):163-70.
2008: Lai Ying-Ju; Pullamsetti Soni Savai; Dony Eva; Weissmann Norbert; Butrous Ghazwan; Banat Gamal-Andre; Ghofrani Hossein Ardeschir; Seeger Werner; Grimminger Friedrich; Schermuly Ralph Theo
Role of the prostanoid EP4 receptor in iloprost-mediated vasodilatation in pulmonary hypertension.
American journal of respiratory and critical care medicine 2008;178(2):188-96.
2008: Yu Haiying; Königshoff Melanie; Jayachandran Aparna; Handley Dan; Seeger Werner; Kaminski Naftali; Eickelberg Oliver
Transgelin is a direct target of TGF-beta/Smad3-dependent epithelial cell migration in lung fibrosis.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(6):1778-89.
2008: Vadász István; Schermuly Ralph T; Ghofrani Hossein A; Rummel Sebastian; Wehner Susan; Mühldorfer Inge; Schäfer Klaus P; Seeger Werner; Morty Rory E; Grimminger Friedrich; Weissmann Norbert
The lectin-like domain of tumor necrosis factor-alpha improves alveolar fluid balance in injured isolated rabbit lungs.
Critical care medicine 2008;36(5):1543-50.
2008: Gessler Tobias; Seeger Werner; Schmehl Thomas
Inhaled prostanoids in the therapy of pulmonary hypertension.
Journal of aerosol medicine and pulmonary drug delivery 2008;21(1):1-12.
2008: Mayer Konstantin; Seeger Werner
Fish oil in critical illness.
Current opinion in clinical nutrition and metabolic care 2008;11(2):121-7.
2008: Dony E; Lai Y-J; Dumitrascu R; Pullamsetti S S; Savai R; Ghofrani H A; Weissmann N; Schudt C; Flockerzi D; Seeger W; Grimminger F; Schermuly R T
Partial reversal of experimental pulmonary hypertension by phosphodiesterase-3/4 inhibition.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2008;31(3):599-610.
2008: Lahnstein Kerstin; Schmehl Thomas; Rüsch Ute; Rieger Monika; Seeger Werner; Gessler Tobias
Pulmonary absorption of aerosolized fluorescent markers in the isolated rabbit lung.
International journal of pharmaceutics 2008;351(1-2):158-64.
2008: Schulz R; Eisele H-J; Reichenberger F; Seeger W
[Obstructive sleep apnoea and metabolic syndrome]
Pneumologie (Stuttgart, Germany) 2008;62(2):88-91.
2008: Vadász István; Dada Laura A; Briva Arturo; Trejo Humberto E; Welch Lynn C; Chen Jiwang; Tóth Péter T; Lecuona Emilia; Witters Lee A; Schumacker Paul T; Chandel Navdeep S; Seeger Werner; Sznajder Jacob I
AMP-activated protein kinase regulates CO2-induced alveolar epithelial dysfunction in rats and human cells by promoting Na,K-ATPase endocytosis.
The Journal of clinical investigation 2008;118(2):752-62.
2008: Alejandre-Alcázar Miguel A; Michiels-Corsten Matthias; Vicencio Alfin G; Reiss Irwin; Ryu Julie; de Krijger Ronald R; Haddad Gabriel G; Tibboel Dick; Seeger Werner; Eickelberg Oliver; Morty Rory E
TGF-beta signaling is dynamically regulated during the alveolarization of rodent and human lungs.
Developmental dynamics : an official publication of the American Association of Anatomists 2008;237(1):259-69.
2008: Kiss Ladislau; Röder Yasmin; Bier Jens; Weissmann Norbert; Seeger Werner; Grimminger Friedrich
Direct eicosanoid profiling of the hypoxic lung by comprehensive analysis via capillary liquid chromatography with dual online photodiode-array and tandem mass-spectrometric detection.
Analytical and bioanalytical chemistry 2008;390(2):697-714.
2008: Kitowska Kamila; Zakrzewicz Dariusz; Königshoff Melanie; Chrobak Izabella; Grimminger Friedrich; Seeger Werner; Bulau Patrick; Eickelberg Oliver
Functional role and species-specific contribution of arginases in pulmonary fibrosis.
American journal of physiology. Lung cellular and molecular physiology 2008;294(1):L34-45.
2008: Cabanski Maciej; Steinmüller Mirko; Marsh Leigh M; Surdziel Ewa; Seeger Werner; Lohmeyer Jürgen
PKR regulates TLR2/TLR4-dependent signaling in murine alveolar macrophages.
American journal of respiratory cell and molecular biology 2008;38(1):26-31.
2008: Dumitrascu Rio; Koebrich Silke; Dony Eva; Weissmann Norbert; Savai Rajkumar; Pullamsetti Soni S; Ghofrani Hossein A; Samidurai Arun; Traupe Horst; Seeger Werner; Grimminger Friedrich; Schermuly Ralph T
Characterization of a murine model of monocrotaline pyrrole-induced acute lung injury.
BMC pulmonary medicine 2008;8():25.
2008: Königshoff Melanie; Balsara Nisha; Pfaff Eva-Maria; Kramer Monika; Chrobak Izabella; Seeger Werner; Eickelberg Oliver
Functional Wnt signaling is increased in idiopathic pulmonary fibrosis.
PloS one 2008;3(5):e2142.
2008: Kouri Fotini M; Queisser Markus A; Königshoff Melanie; Chrobak Izabella; Preissner Klaus T; Seeger Werner; Eickelberg Oliver
Plasminogen activator inhibitor type 1 inhibits smooth muscle cell proliferation in pulmonary arterial hypertension.
The international journal of biochemistry & cell biology 2008;40(9):1872-82.
2007: Königshoff Melanie; Wilhelm Anke; Jahn Andreas; Sedding Daniel; Amarie Oana Veronica; Eul Bastian; Seeger Werner; Fink Ludger; Günther Andreas; Eickelberg Oliver; Rose Frank
The angiotensin II receptor 2 is expressed and mediates angiotensin II signaling in lung fibrosis.
American journal of respiratory cell and molecular biology 2007;37(6):640-50.
2007: Reichenberger Frank; Kohstall Markus G; Seeger Timon; Olschewski Horst; Grimminger Friedrich; Seeger Werner; Ghofrani Hossein A
Effect of sildenafil on hypoxia-induced changes in pulmonary circulation and right ventricular function.
Respiratory physiology & neurobiology 2007;159(2):196-201.
2007: von Wulffen Werner; Steinmueller Mirko; Herold Susanne; Marsh Leigh M; Bulau Patrick; Seeger Werner; Welte Tobias; Lohmeyer Jürgen; Maus Ulrich A
Lung dendritic cells elicited by Fms-like tyrosine 3-kinase ligand amplify the lung inflammatory response to lipopolysaccharide.
American journal of respiratory and critical care medicine 2007;176(9):892-901.
2007: Reichenberger F; Voswinckel R; Enke B; Rutsch M; El Fechtali E; Schmehl T; Olschewski H; Schermuly R; Weissmann N; Ghofrani H A; Grimminger F; Mayer E; Seeger W
Long-term treatment with sildenafil in chronic thromboembolic pulmonary hypertension.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2007;30(5):922-7.
2007: Alejandre-Alcázar Miguel A; Shalamanov Petar D; Amarie Oana V; Sevilla-Pérez Julia; Seeger Werner; Eickelberg Oliver; Morty Rory E
Temporal and spatial regulation of bone morphogenetic protein signaling in late lung development.
Developmental dynamics : an official publication of the American Association of Anatomists 2007;236(10):2825-35.
2007: Weissmann Norbert; Gerigk Boris; Kocer Ozlem; Nollen Matthias; Hackemack Sascha; Ghofrani Hossein Ardeschir; Schermuly Ralph Theo; Butrous Ghazwan; Schulz Andreas; Roth Markus; Seeger Werner; Grimminger Friedrich
Hypoxia-induced pulmonary hypertension: different impact of iloprost, sildenafil, and nitric oxide.
Respiratory medicine 2007;101(10):2125-32.
2007: Mittal Manish; Roth Markus; König Peter; Hofmann Simone; Dony Eva; Goyal Parag; Selbitz Anne-Christin; Schermuly Ralph Theo; Ghofrani Hossein Ardeschir; Kwapiszewska Grazyna; Kummer Wolfgang; Klepetko Walter; Hoda Mir Ali Reza; Fink Ludger; Hänze Jörg; Seeger Werner; Grimminger Friedrich; Schmidt Harald H H W; Weissmann Norbert
Hypoxia-dependent regulation of nonphagocytic NADPH oxidase subunit NOX4 in the pulmonary vasculature.
Circulation research 2007;101(3):258-67.
2007: Morty Rory E; Eickelberg Oliver; Seeger Werner
Alveolar fluid clearance in acute lung injury: what have we learned from animal models and clinical studies?
Intensive care medicine 2007;33(7):1229-40.
2007: Markart Philipp; Ruppert Clemens; Wygrecka Malgorzata; Colaris Thorsten; Dahal Bhola; Walmrath Dieter; Harbach Heinz; Wilhelm Jochen; Seeger Werner; Schmidt Reinhold; Guenther Andreas
Patients with ARDS show improvement but not normalisation of alveolar surface activity with surfactant treatment: putative role of neutral lipids.
Thorax 2007;62(7):588-94.
2007: Zakrzewicz Anna; Hecker Matthias; Marsh Leigh M; Kwapiszewska Grazyna; Nejman Bozena; Long Lu; Seeger Werner; Schermuly Ralph T; Morrell Nicholas W; Morty Rory E; Eickelberg Oliver
Receptor for activated C-kinase 1, a novel interaction partner of type II bone morphogenetic protein receptor, regulates smooth muscle cell proliferation in pulmonary arterial hypertension.
Circulation 2007;115(23):2957-68.
2007: Lasch H G; Seeger W
[The development of internal medicine. Observations within the context of all medicine and future prospects]
Der Internist 2007;48 Suppl 1():S13-6.
2007: Zakrzewicz A; Kouri F M; Nejman B; Kwapiszewska G; Hecker M; Sandu R; Dony E; Seeger W; Schermuly R T; Eickelberg O; Morty R E
The transforming growth factor-beta/Smad2,3 signalling axis is impaired in experimental pulmonary hypertension.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2007;29(6):1094-104.
2007: Wygrecka M; Markart P; Ruppert C; Petri K; Preissner K T; Seeger W; Guenther A
Cellular origin of pro-coagulant and (anti)-fibrinolytic factors in bleomycin-injured lungs.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2007;29(6):1105-14.
2007: Hänze Jörg; Weissmann Norbert; Grimminger Friedrich; Seeger Werner; Rose Frank
Cellular and molecular mechanisms of hypoxia-inducible factor driven vascular remodeling.
Thrombosis and haemostasis 2007;97(5):774-87.
2007: Schermuly Ralph Theo; Pullamsetti Soni Savai; Kwapiszewska Grazyna; Dumitrascu Rio; Tian Xia; Weissmann Norbert; Ghofrani Hossein Ardeschir; Kaulen Christina; Dunkern Torsten; Schudt Christian; Voswinckel Robert; Zhou Jiang; Samidurai Arun; Klepetko Walter; Paddenberg Renate; Kummer Wolfgang; Seeger Werner; Grimminger Friedrich
Phosphodiesterase 1 upregulation in pulmonary arterial hypertension: target for reverse-remodeling therapy.
Circulation 2007;115(17):2331-9.
2007: Morty Rory E; Nejman Bozena; Kwapiszewska Grazyna; Hecker Matthias; Zakrzewicz Anka; Kouri Fotini M; Peters Dorothea M; Dumitrascu Rio; Seeger Werner; Knaus Petra; Schermuly Ralph T; Eickelberg Oliver
Dysregulated bone morphogenetic protein signaling in monocrotaline-induced pulmonary arterial hypertension.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(5):1072-8.
2007: Maus Ulrich A; Backi Myriam; Winter Christine; Srivastava Mrigank; Schwarz Matthias K; Rückle Thomas; Paton James C; Briles David; Mack Matthias; Welte Tobias; Maus Regina; Bohle Rainer M; Seeger Werner; Rommel Christian; Hirsch Emilio; Lohmeyer Jürgen; Preissner Klaus T
Importance of phosphoinositide 3-kinase gamma in the host defense against pneumococcal infection.
American journal of respiratory and critical care medicine 2007;175(9):958-66.
2007: Greschus Susanne; Savai Rajkumar; Wolf Joachim Claudius; Rose Frank; Seeger Werner; Fitzgerald Paul; Traupe Horst
Non-invasive screening of lung nodules in mice comparing a novel volumetric computed tomography with a clinical multislice CT.
Oncology reports 2007;17(4):707-12.
2007: Günther A; Enke B; Markart P; Hammerl P; Morr H; Behr J; Stähler G; Seeger W; Grimminger F; Leconte I; Roux S; Ghofrani H-A
Safety and tolerability of bosentan in idiopathic pulmonary fibrosis: an open label study.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2007;29(4):713-9.
2007: Schaefer Martina Barbara; Ott Juliane; Mohr Andrea; Bi Ming Hua; Grosz Andrea; Weissmann Norbert; Ishii Satoshi; Grimminger Friedrich; Seeger Werner; Mayer Konstantin
Immunomodulation by n-3- versus n-6-rich lipid emulsions in murine acute lung injury--role of platelet-activating factor receptor.
Critical care medicine 2007;35(2):544-54.
2007: Alejandre-Alcázar Miguel A; Kwapiszewska Grazyna; Reiss Irwin; Amarie Oana V; Marsh Leigh M; Sevilla-Pérez Julia; Wygrecka Malgorzata; Eul Bastian; Köbrich Silke; Hesse Mareike; Schermuly Ralph T; Seeger Werner; Eickelberg Oliver; Morty Rory E
Hyperoxia modulates TGF-beta/BMP signaling in a mouse model of bronchopulmonary dysplasia.
American journal of physiology. Lung cellular and molecular physiology 2007;292(2):L537-49.
2007: Markart P; Ruppert C; Wygrecka M; Schmidt R; Korfei M; Harbach H; Theruvath I; Pison U; Seeger W; Guenther A; Witt H
Surfactant protein C mutations in sporadic forms of idiopathic interstitial pneumonias.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2007;29(1):134-7.
2007: Schmidt Reinhold; Markart Philipp; Ruppert Clemens; Wygrecka Malgorzata; Kuchenbuch Tim; Walmrath Dieter; Seeger Werner; Guenther Andreas
Time-dependent changes in pulmonary surfactant function and composition in acute respiratory distress syndrome due to pneumonia or aspiration.
Respiratory research 2007;8():55.
2007: Schermuly Ralph T; Pullamsetti Soni S; Breitenbach Susanne C; Weissmann Norbert; Ghofrani Hossein A; Grimminger Friedrich; Nilius Sigrid M; Schrör Karsten; Kirchrath Jutta M; Seeger Werner; Rose Frank
Iloprost-induced desensitization of the prostacyclin receptor in isolated rabbit lungs.
Respiratory research 2007;8():4.
2006: Weissmann Norbert; Dietrich Alexander; Fuchs Beate; Kalwa Hermann; Ay Mahmut; Dumitrascu Rio; Olschewski Andrea; Storch Ursula; Mederos y Schnitzler Michael; Ghofrani Hossein Ardeschir; Schermuly Ralph Theo; Pinkenburg Olaf; Seeger Werner; Grimminger Friedrich; Gudermann Thomas
Classical transient receptor potential channel 6 (TRPC6) is essential for hypoxic pulmonary vasoconstriction and alveolar gas exchange.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(50):19093-8.
2006: Krishnaveni Manda S; Hansen Jakob Lerche; Seeger Werner; Morty Rory E; Sheikh Søren P; Eickelberg Oliver
Constitutive homo- and hetero-oligomerization of TbetaRII-B, an alternatively spliced variant of the mouse TGF-beta type II receptor.
Biochemical and biophysical research communications 2006;351(3):651-7.
2006: Voswinckel Robert; Enke Beate; Reichenberger Frank; Kohstall Markus; Kreckel Andree; Krick Stefanie; Gall Henning; Gessler Tobias; Schmehl Thomas; Ghofrani Hossein A; Schermuly Ralph Theo; Grimminger Friedrich; Rubin Lewis J; Seeger Werner; Olschewski Horst
Favorable effects of inhaled treprostinil in severe pulmonary hypertension: results from randomized controlled pilot studies.
Journal of the American College of Cardiology 2006;48(8):1672-81.
2006: Ghofrani Hossein A; Voswinckel Robert; Reichenberger Frank; Weissmann Norbert; Schermuly Ralph T; Seeger Werner; Grimminger Friedrich
Hypoxia- and non-hypoxia-related pulmonary hypertension - established and new therapies.
Cardiovascular research 2006;72(1):30-40.
2006: Ruppert Clemens; Bagheri Ariane; Markart Philipp; Schmidt Reinhold; Seeger Werner; Günther Andreas
Liver carboxylesterase cleaves surfactant protein (SP-) B and promotes surfactant subtype conversion.
Biochemical and biophysical research communications 2006;348(4):1449-54.
2006: Schmidt Reinhold; Markart Philipp; Ruppert Clemens; Temmesfeld Bettina; Nass Robert; Lohmeyer Jürgen; Seeger Werner; Günther Andreas
Pulmonary surfactant in patients with Pneumocystis pneumonia and acquired immunodeficiency syndrome.
Critical care medicine 2006;34(9):2370-6.
2006: Reichenberger F; Voswinckel R; Steveling E; Enke B; Kreckel A; Olschewski H; Grimminger F; Seeger W; Ghofrani H A
Sildenafil treatment for portopulmonary hypertension.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2006;28(3):563-7.
2006: Weissmann Norbert; Sommer Natascha; Schermuly Ralph Theo; Ghofrani Hossein Ardeschir; Seeger Werner; Grimminger Friedrich
Oxygen sensors in hypoxic pulmonary vasoconstriction.
Cardiovascular research 2006;71(4):620-9.
2006: Herold Susanne; von Wulffen Werner; Steinmueller Mirko; Pleschka Stephan; Kuziel William A; Mack Matthias; Srivastava Mrigank; Seeger Werner; Maus Ulrich A; Lohmeyer Juergen
Alveolar epithelial cells direct monocyte transepithelial migration upon influenza virus infection: impact of chemokines and adhesion molecules.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(3):1817-24.
2006: Maus Ulrich A; Janzen Simeon; Wall Gerhard; Srivastava Mrigank; Blackwell Timothy S; Christman John W; Seeger Werner; Welte Tobias; Lohmeyer Jürgen
Resident alveolar macrophages are replaced by recruited monocytes in response to endotoxin-induced lung inflammation.
American journal of respiratory cell and molecular biology 2006;35(2):227-35.
2006: Markart P; Seeger W; Günther A
[Differential therapy of pulmonary fibrosis]
Der Internist 2006;47 Suppl 1():S26-32.
2006: Wilhelm Jochen; Muyal Jai Prakash; Best Johannes; Kwapiszewska Grazyna; Stein Maria Magdalena; Seeger Werner; Bohle Rainer Maria; Fink Ludger
Systematic comparison of the T7-IVT and SMART-based RNA preamplification techniques for DNA microarray experiments.
Clinical chemistry 2006;52(6):1161-7.
2006: Ghofrani H A; Schermuly R T; Weissmann N; Seeger W; Grimminger F
[Reverse remodeling -- paradigm shift in the treatment of pulmonary hypertension]
Deutsche medizinische Wochenschrift (1946) 2006;131(16):871-4.
2006: Voswinckel R; Ahlbrecht K; Wolff J C; Weissmann N; Fehrenbach H; Yildirim A O; Grimminger F; Seeger W
[Pulmonary tissue regeneration -- a hope for the future]
Deutsche medizinische Wochenschrift (1946) 2006;131(16):865-8.
2006: Schulz Richard; Grebe Mathias; Eisele Hans-Joachim; Mayer Konstantin; Weissmann Norbert; Seeger Werner
[Obstructive sleep apnea-related cardiovascular disease]
Medizinische Klinik (Munich, Germany : 1983) 2006;101(4):321-7.
2006: Günther Andreas; Markart Philipp; Eickelberg Oliver; Seeger Werner
[Pulmonary fibrosis--a therapeutic dilemma?]
Medizinische Klinik (Munich, Germany : 1983) 2006;101(4):308-12.
2006: Pullamsetti Soni Savai; Maring Daniel; Ghofrani Hossein Ardeschir; Mayer Konstantin; Weissmann Norbert; Rosengarten Bernhard; Lehner Martin; Schudt Christian; Boer Rainer; Grimminger Friedrich; Seeger Werner; Schermuly Ralph Theo
Effect of nitric oxide synthase (NOS) inhibition on macro- and microcirculation in a model of rat endotoxic shock.
Thrombosis and haemostasis 2006;95(4):720-7.
2006: Olschewski Andrea; Li Yingji; Tang Bi; Hanze Jörg; Eul Bastian; Bohle Rainer M; Wilhelm Jochen; Morty Rory E; Brau Michael E; Weir E Kenneth; Kwapiszewska Grazyna; Klepetko Walter; Seeger Werner; Olschewski Horst
Impact of TASK-1 in human pulmonary artery smooth muscle cells.
Circulation research 2006;98(8):1072-80.
2006: Mayer K; Schaefer M; Walmrath H; Grimminger F; Seeger W
[Nutrition and immunonutrition in septic patients]
Der Internist 2006;47(4):374, 376-82.
2006: Grebe Mathias; Eisele Hans Joachim; Weissmann Norbert; Schaefer Christian; Tillmanns Harald; Seeger Werner; Schulz Richard
Antioxidant vitamin C improves endothelial function in obstructive sleep apnea.
American journal of respiratory and critical care medicine 2006;173(8):897-901.
2006: Weissmann Norbert; Zeller Stefanie; Schäfer Rolf U; Turowski Carmen; Ay Mahmut; Quanz Karin; Ghofrani Hossein A; Schermuly Ralph T; Fink Ludger; Seeger Werner; Grimminger Friedrich
Impact of mitochondria and NADPH oxidases on acute and sustained hypoxic pulmonary vasoconstriction.
American journal of respiratory cell and molecular biology 2006;34(4):505-13.
2006: Renigunta Aparna; Krasteva Gabriela; König Peter; Rose Frank; Klepetko Walter; Grimminger Friedrich; Seeger Werner; Hänze Jörg
DNA transfer into human lung cells is improved with Tat-RGD peptide by caveoli-mediated endocytosis.
Bioconjugate chemistry 2006;17(2):327-34.
2006: Savai Rajkumar; Schermuly Ralph Theo; Schneider Michael; Pullamsetti Soni Savai; Grimminger Friedrich; Seeger Werner; Banat Gamal-Andre
Hybrid-primed lymphocytes and hybrid vaccination prevent tumor growth of lewis lung carcinoma in mice.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2006;29(2):175-87.
2006: Hattar Katja; Grandel Ulrich; Moeller Alexander; Fink Ludger; Iglhaut Julia; Hartung Thomas; Morath Siegfried; Seeger Werner; Grimminger Friedrich; Sibelius Ulf
Lipoteichoic acid (LTA) from Staphylococcus aureus stimulates human neutrophil cytokine release by a CD14-dependent, Toll-like-receptor-independent mechanism: Autocrine role of tumor necrosis factor-[alpha] in mediating LTA-induced interleukin-8 generation.
Critical care medicine 2006;34(3):835-41.
2006: Schulz Richard; Flötotto Christiane; Jahn Andreas; Eisele Hans Joachim; Weissmann Norbert; Seeger Werner; Rose Frank
Circulating adrenomedullin in obstructive sleep apnoea.
Journal of sleep research 2006;15(1):89-95.
2006: Mayer Konstantin; Schaefer Martina B; Seeger Werner
Fish oil in the critically ill: from experimental to clinical data.
Current opinion in clinical nutrition and metabolic care 2006;9(2):140-8.
2006: Renigunta Aparna; Hild Christiane; Rose Frank; Klepetko Walter; Grimminger Friedrich; Seeger Werner; Hänze Jörg
Human RELMbeta is a mitogenic factor in lung cells and induced in hypoxia.
FEBS letters 2006;580(3):900-3.
2006: Dumitrascu Rio; Weissmann Norbert; Ghofrani Hossein Ardeschir; Dony Eva; Beuerlein Knut; Schmidt Harald; Stasch Johannes-Peter; Gnoth Mark Jean; Seeger Werner; Grimminger Friedrich; Schermuly Ralph Theo
Activation of soluble guanylate cyclase reverses experimental pulmonary hypertension and vascular remodeling.
Circulation 2006;113(2):286-95.
2006: Grandel Ulrich; Benkelmann Robin; Buerke Michael; Kiss Ladislau; Hattar Katja; Mayer Konstantin; Heep Martina; Seeger Werner; Grimminger Friedrich; Sibelius Ulf
Free arachidonic versus eicosapentaenoic acid differentially influences the potency of bacterial exotoxins to provoke myocardial depression in isolated rat hearts.
Critical care medicine 2006;34(1):118-26.
2006: Eul Bastian; Rose Frank; Krick Stefanie; Savai Rajkumar; Goyal Parag; Klepetko Walter; Grimminger Friedrich; Weissmann Norbert; Seeger Werner; Hänze Jörg
Impact of HIF-1alpha and HIF-2alpha on proliferation and migration of human pulmonary artery fibroblasts in hypoxia.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(1):163-5.
2006: Schermuly Ralph Theo; Schulz Andreas; Ghofrani Hossein Ardeschir; Breitenbach Christina Susanne; Weissmann Norbert; Hildebrand Michael; Kurz Julia; Grimminger Friedrich; Seeger Werner
Comparison of pharmacokinetics and vasodilatory effect of nebulized and infused iloprost in experimental pulmonary hypertension: rapid tolerance development.
Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine 2006;19(3):353-63.
2006: Weissmann Norbert; Schermuly Ralph T; Ghofrani Hossein A; Hänze Jörg; Goyal Parag; Grimminger Friedrich; Seeger Werner
Hypoxic pulmonary vasoconstriction--triggered by an increase in reactive oxygen species?
Novartis Foundation symposium 2006;272():196-208; discussion 208-17.
2006: Steinmüller Mirko; Srivastava Mrigank; Kuziel William A; Christman John W; Seeger Werner; Welte Tobias; Lohmeyer Jürgen; Maus Ulrich A
Endotoxin induced peritonitis elicits monocyte immigration into the lung: implications on alveolar space inflammatory responsiveness.
Respiratory research 2006;7():30.
2006: Rosengarten B; Schermuly R T; Voswinckel R; Kohstall M G; Olschewski H; Weissmann N; Seeger W; Kaps M; Grimminger F; Ghofrani H A
Sildenafil improves dynamic vascular function in the brain: studies in patients with pulmonary hypertension.
Cerebrovascular diseases (Basel, Switzerland) 2006;21(3):194-200.
2005: Seay Ulrike; Sedding Daniel; Krick Stefanie; Hecker Matthias; Seeger Werner; Eickelberg Oliver
Transforming growth factor-beta-dependent growth inhibition in primary vascular smooth muscle cells is p38-dependent.
The Journal of pharmacology and experimental therapeutics 2005;315(3):1005-12.
2005: Morty Rory E; Vadász István; Bulau Patrick; Dive Vincent; Oliveira Vitor; Seeger Werner; Juliano Luiz
Tropolysin, a new oligopeptidase from African trypanosomes.
Biochemistry 2005;44(44):14658-69.
2005: Schermuly Ralph Theo; Dony Eva; Ghofrani Hossein Ardeschir; Pullamsetti Soni; Savai Rajkumar; Roth Markus; Sydykov Akylbek; Lai Ying Ju; Weissmann Norbert; Seeger Werner; Grimminger Friedrich
Reversal of experimental pulmonary hypertension by PDGF inhibition.
The Journal of clinical investigation 2005;115(10):2811-21.
2005: Savai Rajkumar; Wolf Joachim C; Greschus Susanne; Eul Bastian G; Schermuly Ralph T; Hänze Jörg; Voswinckel Robert; Langheinrich Alexander C; Grimminger Friedrich; Traupe Horst; Seeger Werner; Rose Frank
Analysis of tumor vessel supply in Lewis lung carcinoma in mice by fluorescent microsphere distribution and imaging with micro- and flat-panel computed tomography.
The American journal of pathology 2005;167(4):937-46.
2005: Vadász István; Morty Rory E; Olschewski Andrea; Königshoff Melanie; Kohstall Markus G; Ghofrani Hossein A; Grimminger Friedrich; Seeger Werner
Thrombin impairs alveolar fluid clearance by promoting endocytosis of Na+,K+-ATPase.
American journal of respiratory cell and molecular biology 2005;33(4):343-54.
2005: Hattar Katja; van Bürck Sandra; Bickenbach Annette; Grandel Ulrich; Maus Ulrich; Lohmeyer Jürgen; Csernok Elena; Hartung Thomas; Seeger Werner; Grimminger Friedrich; Sibelius Ulf
Anti-proteinase 3 antibodies (c-ANCA) prime CD14-dependent leukocyte activation.
Journal of leukocyte biology 2005;78(4):992-1000.
2005: Weissmann Norbert; Manz Daniel; Buchspies Daniela; Keller Stephan; Mehling Tanja; Voswinckel Robert; Quanz Karin; Ghofrani Hossein A; Schermuly Ralph T; Fink Ludger; Seeger Werner; Gassmann Max; Grimminger Friedrich
Congenital erythropoietin over-expression causes "anti-pulmonary hypertensive" structural and functional changes in mice, both in normoxia and hypoxia.
Thrombosis and haemostasis 2005;94(3):630-8.
2005: Friese Georg; Lohmeyer Jürgen; Seeger Werner; Grimminger Friedrich; Ghofrani Hossein Ardeschir
[HIV-associated pulmonary hypertension ]
Herz 2005;30(6):481-5.
2005: Markart P; Hundack L; Ghofrani A; Grimminger F; Seeger W; Günther A
[Idiopathic interstitial pneumonias: pathomechanisms and therapeutic options]
Pneumologie (Stuttgart, Germany) 2005;59(8):554-61.
2005: Grandel Ulrich; Hopf Michael; Buerke Michael; Hattar Katja; Heep Martina; Fink Ludger; Bohle Rainer M; Morath Siegfried; Hartung Thomas; Pullamsetti Soni; Schermuly Ralph T; Seeger Werner; Grimminger Friedrich; Sibelius Ulf
Mechanisms of cardiac depression caused by lipoteichoic acids from Staphylococcus aureus in isolated rat hearts.
Circulation 2005;112(5):691-8.
2005: Srivastava Mrigank; Jung Steffen; Wilhelm Jochen; Fink Ludger; Bühling Frank; Welte Tobias; Bohle Rainer M; Seeger Werner; Lohmeyer Jürgen; Maus Ulrich A
The inflammatory versus constitutive trafficking of mononuclear phagocytes into the alveolar space of mice is associated with drastic changes in their gene expression profiles.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(3):1884-93.
2005: Savai Rajkumar; Schermuly Ralph Theo; Voswinckel Robert; Renigunta Aparna; Reichmann Bernd; Eul Bastian; Grimminger Friedrich; Seeger Werner; Rose Frank; Hänze Jörg
HIF-1alpha attenuates tumor growth in spite of augmented vascularization in an A549 adenocarcinoma mouse model.
International journal of oncology 2005;27(2):393-400.
2005: Schermuly Ralph Theo; Yilmaz Hüseyin; Ghofrani Hossein Ardeschir; Woyda Kathrin; Pullamsetti Soni; Schulz Andreas; Gessler Tobias; Dumitrascu Rio; Weissmann Norbert; Grimminger Friedrich; Seeger Werner
Inhaled iloprost reverses vascular remodeling in chronic experimental pulmonary hypertension.
American journal of respiratory and critical care medicine 2005;172(3):358-63.
2005: Eickelberg O; Seeger W
[Pulmonary hypertension: pathophysiology, genetics and functional genomics]
Der Internist 2005;46(7):759-68.
2005: Pullamsetti Soni; Kiss Ladislau; Ghofrani Hossein Ardeschir; Voswinckel Robert; Haredza Peter; Klepetko Walter; Aigner Clemens; Fink Ludger; Muyal Jai Prakash; Weissmann Norbert; Grimminger Friedrich; Seeger Werner; Schermuly Ralph Theo
Increased levels and reduced catabolism of asymmetric and symmetric dimethylarginines in pulmonary hypertension.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(9):1175-7.
2005: Seeger W
[Pneumology -- from phthisiology to regenerative medicine]
Deutsche medizinische Wochenschrift (1946) 2005;130(25-26):1543-6.
2005: Krick Stefanie; Hänze Jörg; Eul Bastian; Savai Rajkumar; Seay Ulrike; Grimminger Friedrich; Lohmeyer Jürgen; Klepetko Walter; Seeger Werner; Rose Frank
Hypoxia-driven proliferation of human pulmonary artery fibroblasts: cross-talk between HIF-1alpha and an autocrine angiotensin system.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(7):857-9.
2005: Krick Stefanie; Eul Bastian G; Hänze Jörg; Savai Rajkumar; Grimminger Friedrich; Seeger Werner; Rose Frank
Role of hypoxia-inducible factor-1alpha in hypoxia-induced apoptosis of primary alveolar epithelial type II cells.
American journal of respiratory cell and molecular biology 2005;32(5):395-403.
2005: Schulz R; Eisele H J; Weissmann N; Seeger W
[Pulmonary hypertension and sleep-related breathing disorders]
Pneumologie (Stuttgart, Germany) 2005;59(4):270-4.
2005: Goyal Parag; Weissmann Norbert; Rose Frank; Grimminger Friedrich; Schäfers Hans J; Seeger Werner; Hänze Jörg
Identification of novel Nox4 splice variants with impact on ROS levels in A549 cells.
Biochemical and biophysical research communications 2005;329(1):32-9.
2005: Olschewski H; Ghofrani A; Enke B; Reichenberger F; Voswinckel R; Kreckel A; Ghofrani S; Wiedemann R; Schulz R; Grimminger F; Seeger W
[Therapy of pulmonary arterial hypertension]
Der Internist 2005;46(3):341-9.
2005: Morty Rory E; Pellé Roger; Vadász István; Uzcanga Graciela L; Seeger Werner; Bubis José
Oligopeptidase B from Trypanosoma evansi. A parasite peptidase that inactivates atrial natriuretic factor in the bloodstream of infected hosts.
The Journal of biological chemistry 2005;280(12):10925-37.
2005: Vadász István; Morty Rory E; Kohstall Markus G; Olschewski Andrea; Grimminger Friedrich; Seeger Werner; Ghofrani Hossein A
Oleic acid inhibits alveolar fluid reabsorption: a role in acute respiratory distress syndrome?
American journal of respiratory and critical care medicine 2005;171(5):469-79.
2005: Schulz R; Eisele H J; Seeger W
Nocturnal atrial fibrillation in a patient with obstructive sleep apnoea.
Thorax 2005;60(2):174.
2005: Maus Ulrich A; Wellmann Sandra; Hampl Christine; Kuziel William A; Srivastava Mrigank; Mack Matthias; Everhart M Brett; Blackwell Timothy S; Christman John W; Schlöndorff Detlef; Bohle Rainer M; Seeger Werner; Lohmeyer Jürgen
CCR2-positive monocytes recruited to inflamed lungs downregulate local CCL2 chemokine levels.
American journal of physiology. Lung cellular and molecular physiology 2005;288(2):L350-8.
2005: Schulz R; Seeger W; Fegbeutel C; Hüsken H; Bödeker R H; Tillmanns H; Grebe M
Changes in extracranial arteries in obstructive sleep apnoea.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2005;25(1):69-74.
2005: Pullamsetti Soni; Krick Stefanie; Yilmaz Hüseyin; Ghofrani Hossein Ardeschir; Schudt Christian; Weissmann Norbert; Fuchs Beate; Seeger Werner; Grimminger Friedrich; Schermuly Ralph Theo
Inhaled tolafentrine reverses pulmonary vascular remodeling via inhibition of smooth muscle cell migration.
Respiratory research 2005;6():128.
2005: Kwapiszewska Grazyna; Wilhelm Jochen; Wolff Stephanie; Laumanns Isabel; Koenig Inke R; Ziegler Andreas; Seeger Werner; Bohle Rainer M; Weissmann Norbert; Fink Ludger
Expression profiling of laser-microdissected intrapulmonary arteries in hypoxia-induced pulmonary hypertension.
Respiratory research 2005;6():109.
2005: Weissmann Norbert; Kuzkaya Nermin; Fuchs Beate; Tiyerili Vedat; Schäfer Rolf U; Schütte Hartwig; Ghofrani Hossein A; Schermuly Ralph T; Schudt Christian; Sydykov Akylbek; Egemnazarow Bakytbek; Seeger Werner; Grimminger Friedrich
Detection of reactive oxygen species in isolated, perfused lungs by electron spin resonance spectroscopy.
Respiratory research 2005;6():86.
2005: Schermuly Ralph Theo; Inholte Christiane; Ghofrani Hossein Ardeschir; Gall Henning; Weissmann Norbert; Weidenbach Andreas; Seeger Werner; Grimminger Friedrich
Lung vasodilatory response to inhaled iloprost in experimental pulmonary hypertension: amplification by different type phosphodiesterase inhibitors.
Respiratory research 2005;6():76.
2004: Bode Lars; Kunz Clemens; Muhly-Reinholz Marion; Mayer Konstantin; Seeger Werner; Rudloff Silvia
Inhibition of monocyte, lymphocyte, and neutrophil adhesion to endothelial cells by human milk oligosaccharides.
Thrombosis and haemostasis 2004;92(6):1402-10.
2004: Kwapiszewska Grazyna; Meyer Markus; Bogumil Ralf; Bohle Rainer M; Seeger Werner; Weissmann Norbert; Fink Ludger
Identification of proteins in laser-microdissected small cell numbers by SELDI-TOF and Tandem MS.
BMC biotechnology 2004;4():30.
2004: Schmidt R; Luboeinski T; Markart P; Ruppert C; Daum C; Grimminger F; Seeger W; Günther A
Alveolar antioxidant status in patients with acute respiratory distress syndrome.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2004;24(6):994-9.
2004: Ghofrani Hossein A; Voswinckel Robert; Reichenberger Frank; Olschewski Horst; Haredza Peter; Karadas Burcu; Schermuly Ralph T; Weissmann Norbert; Seeger Werner; Grimminger Friedrich
Differences in hemodynamic and oxygenation responses to three different phosphodiesterase-5 inhibitors in patients with pulmonary arterial hypertension: a randomized prospective study.
Journal of the American College of Cardiology 2004;44(7):1488-96.
2004: Voswinckel R; Motejl V; Fehrenbach A; Wegmann M; Mehling T; Fehrenbach H; Seeger W
Characterisation of post-pneumonectomy lung growth in adult mice.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2004;24(4):524-32.
2004: Wygrecka Malgorzata; Markart Philipp; Ruppert Clemens; Kuchenbuch Tim; Fink Ludger; Bohle Rainer Maria; Grimminger Friedrich; Seeger Werner; Günther Andreas
Compartment- and cell-specific expression of coagulation and fibrinolysis factors in the murine lung undergoing inhalational versus intravenous endotoxin application.
Thrombosis and haemostasis 2004;92(3):529-40.
2004: Ghofrani Hossein A; Reichenberger Frank; Kohstall Markus G; Mrosek Eike H; Seeger Timon; Olschewski Horst; Seeger Werner; Grimminger Friedrich
Sildenafil increased exercise capacity during hypoxia at low altitudes and at Mount Everest base camp: a randomized, double-blind, placebo-controlled crossover trial.
Annals of internal medicine 2004;141(3):169-77.
2004: Maus Ulrich A; Srivastava Mrigank; Paton James C; Mack Matthias; Everhart M Brett; Blackwell Timothy S; Christman John W; Schlöndorff Detlef; Seeger Werner; Lohmeyer Jürgen
Pneumolysin-induced lung injury is independent of leukocyte trafficking into the alveolar space.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(2):1307-12.
2004: Seeger W; Schulz R
[Inhalation combination therapy in chronic obstructive lung disease. TRISTAN-study]
Der Internist 2004;45(6):727-8.
2004: Olschewski Horst; Rose Frank; Schermuly Ralph; Ghofrani H Ardeschir; Enke Beate; Olschewski Andrea; Seeger Werner
Prostacyclin and its analogues in the treatment of pulmonary hypertension.
Pharmacology & therapeutics 2004;102(2):139-53.
2004: Goyal Parag; Weissmann Norbert; Grimminger Friedrich; Hegel Cornelia; Bader Lucius; Rose Frank; Fink Ludger; Ghofrani Hossein A; Schermuly Ralph T; Schmidt Harald H H W; Seeger Werner; Hänze Jörg
Upregulation of NAD(P)H oxidase 1 in hypoxia activates hypoxia-inducible factor 1 via increase in reactive oxygen species.
Free radical biology & medicine 2004;36(10):1279-88.
2004: Schermuly Ralph Theo; Kreisselmeier Klaus Peter; Ghofrani Hossein Ardeschir; Samidurai Arun; Pullamsetti Soni; Weissmann Norbert; Schudt Christian; Ermert Leander; Seeger Werner; Grimminger Friedrich
Antiremodeling effects of iloprost and the dual-selective phosphodiesterase 3/4 inhibitor tolafentrine in chronic experimental pulmonary hypertension.
Circulation research 2004;94(8):1101-8.
2004: Weissmann Norbert; Vogels Henrik; Schermuly Ralph T; Ghofrani Hossein A; Hänze Jörg; Fink Ludger; Rose Frank; Seeger Werner; Grimminger Friedrich
Measurement of exhaled hydrogen peroxide from rabbit lungs.
Biological chemistry 2004;385(3-4):259-64.
2004: Schmidt Reinhold; Ruppert Clemens; Markart Philipp; Lübke Norbert; Ermert Leander; Weissmann Norbert; Breithecker Andreas; Ermert Monika; Seeger Werner; Günther Andreas
Changes in pulmonary surfactant function and composition in bleomycin-induced pneumonitis and fibrosis.
Toxicology and applied pharmacology 2004;195(2):218-31.
2004: Ghofrani H A; Friese G; Discher T; Olschewski H; Schermuly R T; Weissmann N; Seeger W; Grimminger F; Lohmeyer J
Inhaled iloprost is a potent acute pulmonary vasodilator in HIV-related severe pulmonary hypertension.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2004;23(2):321-6.
2004: Günther Andreas; Balser Markus; Schmidt Reinhold; Markart Philipp; Olk Alexander; Börgermann Jochen; Splittgerber Fred H; Seeger Werner; Friedrich Ivar
Surfactant abnormalities after single lung transplantation in dogs: impact of bronchoscopic surfactant administration.
The Journal of thoracic and cardiovascular surgery 2004;127(2):344-54.
2004: Friedrich Ivar; Börgermann Jochen; Splittgerber Fred H; Brinkmann Matthias; Reidemeister J Christoph; Silber Rolf E; Seeger Werner; Schmidt Reinhold; Günther Andreas
Bronchoscopic surfactant administration preserves gas exchange and pulmonary compliance after single lung transplantation in dogs.
The Journal of thoracic and cardiovascular surgery 2004;127(2):335-43.
2004: Weissmann Norbert; Akkayagil Ercan; Quanz Karin; Schermuly Ralph Theo; Ghofrani Hossein Ardeschir; Fink Ludger; Hänze Jörg; Rose Frank; Seeger Werner; Grimminger Friedrich
Basic features of hypoxic pulmonary vasoconstriction in mice.
Respiratory physiology & neurobiology 2004;139(2):191-202.
2004: Schmidt Reinhold; Schäfer Christoph; Luboeinski Thomas; Löckinger Alexander; Hermle Gerd; Grimminger Friedrich; Seeger Werner; Ghofrani Ardeschir; Schütte Hartwig; Günther Andreas
Increase in alveolar antioxidant levels in hyperoxic and anoxic ventilated rabbit lungs during ischemia.
Free radical biology & medicine 2004;36(1):78-89.
2004: Schulz Richard; Fegbeutel Christine; Olschewski Horst; Rose Frank; Schäfers Hans-Joachim; Seeger Werner
Reversal of nocturnal periodic breathing in primary pulmonary hypertension after lung transplantation.
Chest 2004;125(1):344-7.
2004: Muth H; Maus U; Wygrecka M; Lohmeyer J; Grimminger F; Seeger W; Günther A
Pro- and antifibrinolytic properties of human pulmonary microvascular versus artery endothelial cells: impact of endotoxin and tumor necrosis factor-alpha.
Critical care medicine 2004;32(1):217-26.
2004: Schermuly Ralph T; Kreisselmeier Klaus P; Ghofrani Hossein A; Yilmaz Hüseyin; Butrous Ghazwan; Ermert Leander; Ermert Monika; Weissmann Norbert; Rose Frank; Guenther Andreas; Walmrath Dieter; Seeger Werner; Grimminger Friedrich
Chronic sildenafil treatment inhibits monocrotaline-induced pulmonary hypertension in rats.
American journal of respiratory and critical care medicine 2004;169(1):39-45.
2003: Hänze Jörg; Eul Bastian G; Savai Rajkumar; Krick Stefanie; Goyal Parag; Grimminger Friedrich; Seeger Werner; Rose Frank
RNA interference for HIF-1alpha inhibits its downstream signalling and affects cellular proliferation.
Biochemical and biophysical research communications 2003;312(3):571-7.
2003: Günther Andreas; Lübke Norbert; Ermert Monika; Schermuly Ralph T; Weissmann Norbert; Breithecker Andreas; Markart Philipp; Ruppert Clemens; Quanz Karin; Ermert Leander; Grimminger Friedrich; Seeger Werner
Prevention of bleomycin-induced lung fibrosis by aerosolization of heparin or urokinase in rabbits.
American journal of respiratory and critical care medicine 2003;168(11):1358-65.
2003: Weissmann Norbert; Ebert Nadine; Ahrens Marit; Ghofrani Hossein A; Schermuly Ralph T; Hänze Jörg; Fink Ludger; Rose Frank; Conzen Jörg; Seeger Werner; Grimminger Friedrich
Effects of mitochondrial inhibitors and uncouplers on hypoxic vasoconstriction in rabbit lungs.
American journal of respiratory cell and molecular biology 2003;29(6):721-32.
2003: Mayer Konstantin; Meyer Sandra; Reinholz-Muhly Marion; Maus Ulrich; Merfels Martina; Lohmeyer Jürgen; Grimminger Friedrich; Seeger Werner
Short-time infusion of fish oil-based lipid emulsions, approved for parenteral nutrition, reduces monocyte proinflammatory cytokine generation and adhesive interaction with endothelium in humans.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(9):4837-43.
2003: Mayer Konstantin; Fegbeutel Christine; Hattar Katja; Sibelius Ulf; Krämer Hans-Joachim; Heuer Kai-Uwe; Temmesfeld-Wollbrück Bettina; Gokorsch Stephanie; Grimminger Friedrich; Seeger Werner
Omega-3 vs. omega-6 lipid emulsions exert differential influence on neutrophils in septic shock patients: impact on plasma fatty acids and lipid mediator generation.
Intensive care medicine 2003;29(9):1472-81.
2003: Schermuly R T; Leuchte H; Ghofrani H A; Weissmann N; Rose F; Kohstall M; Olschewski H; Schudt C; Grimminger F; Seeger W; Walmrath D
Zardaverine and aerosolised iloprost in a model of acute respiratory failure.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2003;22(2):342-7.
2003: Voswinckel Robert; Ziegelhoeffer Tibor; Heil Matthias; Kostin Sawa; Breier Georg; Mehling Tanja; Haberberger Rainer; Clauss Matthias; Gaumann Andreas; Schaper Wolfgang; Seeger Werner
Circulating vascular progenitor cells do not contribute to compensatory lung growth.
Circulation research 2003;93(4):372-9.
2003: Ghofrani Hossein A; Rose Frank; Schermuly Ralph T; Olschewski Horst; Wiedemann Ralph; Kreckel André; Weissmann Norbert; Ghofrani Stefanie; Enke Beate; Seeger Werner; Grimminger Friedrich
Oral sildenafil as long-term adjunct therapy to inhaled iloprost in severe pulmonary arterial hypertension.
Journal of the American College of Cardiology 2003;42(1):158-64.
2003: Ermert M; Pantazis C; Duncker H-R; Grimminger F; Seeger W; Ermert L
In situ localization of TNFalpha/beta, TACE and TNF receptors TNF-R1 and TNF-R2 in control and LPS-treated lung tissue.
Cytokine 2003;22(3-4):89-100.
2003: Ruppert Clemens; Pucker Carolin; Markart Philipp; Seibold Kerstin; Bagheri Ariane; Grimminger Fritz; Seeger Werner; Günther Andreas
Impact of surface tension on the conversion rate of large to small surfactant aggregates.
Biophysical chemistry 2003;104(1):229-38.
2003: Mayer Konstantin; Gokorsch Stephanie; Fegbeutel Christine; Hattar Katja; Rosseau Simone; Walmrath Dieter; Seeger Werner; Grimminger Friedrich
Parenteral nutrition with fish oil modulates cytokine response in patients with sepsis.
American journal of respiratory and critical care medicine 2003;167(10):1321-8.
2003: Schulz Richard; Fegbeutel Christine; Althoff Andre; Traupe Horst; Grimminger Friedrich; Seeger Werner
Central sleep apnoea and unilateral diaphragmatic paralysis associated with vertebral artery compression of the medulla oblongata.
Journal of neurology 2003;250(4):503-5.
2003: Ghofrani Hossein A; Schermuly Ralph T; Rose Frank; Wiedemann Ralph; Kohstall Markus G; Kreckel André; Olschewski Horst; Weissmann Norbert; Enke Beate; Ghofrani Stefanie; Seeger Werner; Grimminger Friedrich
Sildenafil for long-term treatment of nonoperable chronic thromboembolic pulmonary hypertension.
American journal of respiratory and critical care medicine 2003;167(8):1139-41.
2003: Schütte Hartwig; Schell Alexander; Schäfer Christoph; Ghofrani Ardeschir; Theo Schermuly Ralph; Seeger Werner; Grimminger Friedrich
Subthreshold doses of nebulized prostacyclin and rolipram synergistaically protect against lung ischemia-reperfusion.
Transplantation 2003;75(6):814-21.
2003: Ermert Monika; Kuttner Daniel; Eisenhardt Nils; Dierkes Christian; Seeger Werner; Ermert Leander
Cyclooxygenase-2-dependent and thromboxane-dependent vascular and bronchial responses are regulated via p38 mitogen-activated protein kinase in control and endotoxin-primed rat lungs.
Laboratory investigation; a journal of technical methods and pathology 2003;83(3):333-47.
2003: Sibelius Ulf; Grandel Ulrich; Buerke Michael; Kiss Ladislau; Klingenberger Pascal; Heep Martina; Bournelis Emmanoyil; Seeger Werner; Grimminger Friedrich
Leukotriene-mediated coronary vasoconstriction and loss of myocardial contractility evoked by low doses of Escherichia coli hemolysin in perfused rat hearts.
Critical care medicine 2003;31(3):683-8.
2003: Maus Ulrich A; Waelsch Katharina; Kuziel William A; Delbeck Tim; Mack Matthias; Blackwell Timothy S; Christman John W; Schlöndorff Detlef; Seeger Werner; Lohmeyer Jürgen
Monocytes are potent facilitators of alveolar neutrophil emigration during lung inflammation: role of the CCL2-CCR2 axis.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(6):3273-8.
2003: Weissmann Norbert; Nollen Matthias; Gerigk Boris; Ardeschir Ghofrani Hossein; Schermuly Ralph Theo; Gunther Andreas; Quanz Karin; Fink Ludger; Hänze Jörg; Rose Frank; Seeger Werner; Grimminger Friedrich
Downregulation of hypoxic vasoconstriction by chronic hypoxia in rabbits: effects of nitric oxide.
American journal of physiology. Heart and circulatory physiology 2003;284(3):H931-8.
2003: Friedrich Bernd; Schmidt Reinhold; Reiss Irwin; Günther Andreas; Seeger Werner; Müller Matthias; Thul Joseph; Schranz Dietmar; Gortner Ludwig
Changes in biochemical and biophysical surfactant properties with cardiopulmonary bypass in children.
Critical care medicine 2003;31(1):284-90.
2003: Ruppert Clemens; Markart Philipp; Schmidt Reinhold; Grimminger Friedrich; Seeger Werner; Lehr Claus-Michael; Günther Andreas
Chemical crosslinking of urokinase to pulmonary surfactant protein B for targeting alveolar fibrin.
Thrombosis and haemostasis 2003;89(1):53-64.
2003: Ruppert Clemens; Pucker Carolin; Markart Philipp; Schmidt Reinhold; Grimminger Fritz; Seeger Werner; Stürzebecher Jörg; Günther Andreas
Selective inhibition of large-to-small surfactant aggregate conversion by serine protease inhibitors of the bis-benzamidine type.
American journal of respiratory cell and molecular biology 2003;28(1):95-102.
2003: Markart Philipp; Ruppert Clemens; Grimminger Friedrich; Seeger Werner; Günther Andreas
Fibrinolysis-inhibitory capacity of clot-embedded surfactant is enhanced by SP-B and SP-C.
American journal of physiology. Lung cellular and molecular physiology 2003;284(1):L69-76.
2002: Olschewski H; Ghofrani A; Wiedemann R; Rose F; Enke B; Gessler T; Voswinckel R; Kohstall M; Grimminger F; Seeger W
[Pulmonary hypertension]
Der Internist 2002;43(12):1498, 1501-9.
2002: Maus U; Henning S; Wenschuh H; Mayer K; Seeger W; Lohmeyer J
Role of endothelial MCP-1 in monocyte adhesion to inflamed human endothelium under physiological flow.
American journal of physiology. Heart and circulatory physiology 2002;283(6):H2584-91.
2002: Ghofrani H A; Olschewski H; Seeger W; Grimminger F
[Sildenafil for treatment of severe pulmonary hypertension and commencing right-heart failure]
Pneumologie (Stuttgart, Germany) 2002;56(11):665-72.
2002: Ghofrani Hossein A; Rose Frank; Schermuly Ralph T; Olschewski Horst; Wiedemann Ralph; Weissmann Norbert; Schudt Christian; Tenor Herrmann; Seeger Werner; Grimminger Friedrich
Amplification of the pulmonary vasodilatory response to inhaled iloprost by subthreshold phosphodiesterase types 3 and 4 inhibition in severe pulmonary hypertension.
Critical care medicine 2002;30(11):2489-92.
2002: Schermuly Ralph Theo; Schulz Andreas; Ghofrani Hossein Ardeschir; Meidow Arne; Rose Frank; Roehl Axel; Weissmann Norbert; Hildebrand Michael; Kurz Julia; Grimminger Friedrich; Walmrath Dieter; Seeger Werner
Pharmacokinetics and metabolism of infused versus inhaled iloprost in isolated rabbit lungs.
The Journal of pharmacology and experimental therapeutics 2002;303(2):741-5.
2002: Schmidt R; Meier U; Markart P; Grimminger F; Velcovsky H G; Morr H; Seeger W; Günther A
Altered fatty acid composition of lung surfactant phospholipids in interstitial lung disease.
American journal of physiology. Lung cellular and molecular physiology 2002;283(5):L1079-85.
2002: Sibelius Ulf; Hattar Katja; Hoffmann Sabine; Mayer Konstantin; Grandel Ulrich; Schenkel Angelika; Seeger Werner; Grimminger Friedrich
Distinct pathways of lipopolysaccharide priming of human neutrophil respiratory burst: role of lipid mediator synthesis and sensitivity to interleukin-10.
Critical care medicine 2002;30(10):2306-12.
2002: Rose Frank; Grimminger Friedrich; Appel Jutta; Heller Mathias; Pies Volker; Weissmann Norbert; Fink Ludger; Schmidt Sebastian; Krick Stefanie; Camenisch Gieri; Gassmann Max; Seeger Werner; Hänze Jörg
Hypoxic pulmonary artery fibroblasts trigger proliferation of vascular smooth muscle cells: role of hypoxia-inducible transcription factors.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(12):1660-1.
2002: Ghofrani Hossein Ardeschir; Wiedemann Ralph; Rose Frank; Schermuly Ralph T; Olschewski Horst; Weissmann Norbert; Gunther Andreas; Walmrath Dieter; Seeger Werner; Grimminger Friedrich
Sildenafil for treatment of lung fibrosis and pulmonary hypertension: a randomised controlled trial.
Lancet 2002;360(9337):895-900.
2002: Maus Ulrich; von Grote Karen; Kuziel William A; Mack Matthias; Miller Edmund J; Cihak Josef; Stangassinger Manfred; Maus Regina; Schlöndorff Detlef; Seeger Werner; Lohmeyer Jürgen
The role of CC chemokine receptor 2 in alveolar monocyte and neutrophil immigration in intact mice.
American journal of respiratory and critical care medicine 2002;166(3):268-73.
2002: Rose Frank; Guthmann Bernd; Tenenbaum Tobias; Fink Ludger; Ghofrani Ardeschir; Weissmann Norbert; König Peter; Ermert Leander; Dahlem Gabriele; Haenze Joerg; Kummer Wolfgang; Seeger Werner; Grimminger Friedrich
Apical, but not basolateral, endotoxin preincubation protects alveolar epithelial cells against hydrogen peroxide-induced loss of barrier function: the role of nitric oxide synthesis.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(3):1474-81.
2002: Mayer Konstantin; Merfels Martina; Muhly-Reinholz Marion; Gokorsch Stephanie; Rosseau Simone; Lohmeyer Jürgen; Schwarzer Nicole; Krüll Matthias; Suttorp Norbert; Grimminger Friedrich; Seeger Werner
Omega-3 fatty acids suppress monocyte adhesion to human endothelial cells: role of endothelial PAF generation.
American journal of physiology. Heart and circulatory physiology 2002;283(2):H811-8.
2002: Ruppert Clemens; Schmidt Reinhold; Grimminger Friedrich; Suzuki Yasuhiro; Seeger Werner; Lehr Claus-Michael; Günther Andreas
Chemical coupling of a monoclonal antisurfactant protein-B antibody to human urokinase for targeting surfactant-incorporating alveolar fibrin.
Bioconjugate chemistry 2002;13(4):804-11.
2002: Hattar Katja; Bickenbach Annette; Csernok Elena; Rosseau Simone; Grandel Ulrich; Seeger Werner; Grimminger Friedrich; Sibelius Ulf
Wegener's granulomatosis: antiproteinase 3 antibodies induce monocyte cytokine and prostanoid release-role of autocrine cell activation.
Journal of leukocyte biology 2002;71(6):996-1004.
2002: Mayer Konstantin; Schmidt Reinhold; Muhly-Reinholz Marion; Bögeholz Tina; Gokorsch Stephanie; Grimminger Friedrich; Seeger Werner
In vitro mimicry of essential fatty acid deficiency in human endothelial cells by TNFalpha impact of omega-3 versus omega-6 fatty acids.
Journal of lipid research 2002;43(6):944-51.
2002: Maus Ulrich A; Koay M Audrey; Delbeck Tim; Mack Matthias; Ermert Monika; Ermert Leander; Blackwell Timothy S; Christman John W; Schlöndorff Detlef; Seeger Werner; Lohmeyer Jürgen
Role of resident alveolar macrophages in leukocyte traffic into the alveolar air space of intact mice.
American journal of physiology. Lung cellular and molecular physiology 2002;282(6):L1245-52.
2002: Walmrath D; Grimminger F; Pappert D; Knothe C; Obertacke U; Benzing A; Günther A; Schmehl T; Leuchte H; Seeger W
Bronchoscopic administration of bovine natural surfactant in ARDS and septic shock: impact on gas exchange and haemodynamics.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2002;19(5):805-10.
2002: Günther A; Schmidt R; Harodt J; Schmehl T; Walmrath D; Ruppert C; Grimminger F; Seeger W
Bronchoscopic administration of bovine natural surfactant in ARDS and septic shock: impact on biophysical and biochemical surfactant properties.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2002;19(5):797-804.
2002: Mayser Peter; Mayer Konstantin; Mahloudjian Mojgan; Benzing Steffen; Krämer Hans-Joachim; Schill Wolf-Bernhard; Seeger Werner; Grimminger Friedrich
A double-blind, randomized, placebo-controlled trial of n-3 versus n-6 fatty acid-based lipid infusion in atopic dermatitis.
JPEN. Journal of parenteral and enteral nutrition 2002;26(3):151-8.
2002: Ghofrani H A; Wiedemann R; Rose F; Weissmann N; Schermuly R T; Quanz K; Grimminger F; Seeger W; Olschewski H
Lung cGMP release subsequent to NO inhalation in pulmonary hypertension: responders versus nonresponders.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2002;19(4):664-71.
2002: Schulz R; Baseler G; Ghofrani H A; Grimminger F; Olschewski H; Seeger W
Nocturnal periodic breathing in primary pulmonary hypertension.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2002;19(4):658-63.
2002: Ermert Monika; Ruppert Clemens; Günther Andreas; Duncker Hans-Rainer; Seeger Werner; Ermert Leander
Cell-specific nitric oxide synthase-isoenzyme expression and regulation in response to endotoxin in intact rat lungs.
Laboratory investigation; a journal of technical methods and pathology 2002;82(4):425-41.
2002: Ghofrani Hossein Ardeschir; Wiedemann Ralph; Rose Frank; Olschewski Horst; Schermuly Ralph Theo; Weissmann Norbert; Seeger Werner; Grimminger Friedrich
Combination therapy with oral sildenafil and inhaled iloprost for severe pulmonary hypertension.
Annals of internal medicine 2002;136(7):515-22.
2002: Hattar Katja; Grandel Ulrich; Bickenbach Annette; Schwarting Andreas; Mayet Werner-Johannes; Bux Jürgen; Jessen Sönke; Fischer Claus; Seeger Werner; Grimminger Friedrich; Sibelius Ulf
Interaction of antibodies to proteinase 3 (classic anti-neutrophil cytoplasmic antibody) with human renal tubular epithelial cells: impact on signaling events and inflammatory mediator generation.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(6):3057-64.
2002: Hänze Jörg; Groneberg David A; Rose Frank; Hanisch Anika; Dötsch Jörg; Peiser Christian; Seeger Werner; Rascher Wolfgang; Fischer Axel; Grimminger Friedrich
Genomic organization and regulation of a human 7-helix transmembrane receptor which is expressed in pulmonary epithelial cells and induced in hypoxia.
Biochemical and biophysical research communications 2002;291(5):1160-5.
2002: Grandel Ulrich; Reutemann Mathias; Kiss Ladislau; Buerke Michael; Fink Ludger; Bournelis Emmanoyil; Heep Martina; Seeger Werner; Grimminger Friedrich; Sibelius Ulf
Staphylococcal alpha-toxin provokes neutrophil-dependent cardiac dysfunction: role of ICAM-1 and cys-leukotrienes.
American journal of physiology. Heart and circulatory physiology 2002;282(3):H1157-65.
2002: Schmidt Reinhold; Steinhilber Wolfram; Ruppert Clemens; Daum Christina; Grimminger Friedrich; Seeger Werner; Günther Andreas
An ELISA technique for quantification of surfactant apoprotein (SP)-C in bronchoalveolar lavage fluid.
American journal of respiratory and critical care medicine 2002;165(4):470-4.
2002: Rose Frank; Dahlem Gabriele; Guthmann Bernd; Grimminger Friedrich; Maus Ulrich; Hänze Jörg; Duemmer Nils; Grandel Ulrich; Seeger Werner; Ghofrani Hossein Ardeschir
Mediator generation and signaling events in alveolar epithelial cells attacked by S. aureus alpha-toxin.
American journal of physiology. Lung cellular and molecular physiology 2002;282(2):L207-14.
2002: Mayer K; Grimm H; Grimminger F; Seeger W
Parenteral nutrition with n-3 lipids in sepsis.
The British journal of nutrition 2002;87 Suppl 1():S69-75.
2002: Fink Ludger; Kohlhoff Stephanie; Stein Maria Magdalena; Hänze Jörg; Weissmann Norbert; Rose Frank; Akkayagil Ercan; Manz Daniel; Grimminger Friedrich; Seeger Werner; Bohle Rainer Maria
cDNA array hybridization after laser-assisted microdissection from nonneoplastic tissue.
The American journal of pathology 2002;160(1):81-90.
2002: Maus Ulrich; Huwe Julia; Ermert Leander; Ermert Monika; Seeger Werner; Lohmeyer Jügen
Molecular pathways of monocyte emigration into the alveolar air space of intact mice.
American journal of respiratory and critical care medicine 2002;165(1):95-100.
2002: Schulz Richard; Hummel Christoph; Heinemann Sabine; Seeger Werner; Grimminger Friedrich
Serum levels of vascular endothelial growth factor are elevated in patients with obstructive sleep apnea and severe nighttime hypoxia.
American journal of respiratory and critical care medicine 2002;165(1):67-70.
2002: Gessler Tobias; Schmehl Thomas; Olschewski Horst; Grimminger Friedrich; Seeger Werner
Aerosolized vasodilators in pulmonary hypertension.
Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine 2002;15(2):117-22.
2001: Olschewski H; Rose F; Grünig E; Ghofrani H A; Walmrath D; Schulz R; Schermuly R; Grimminger F; Seeger W
Cellular pathophysiology and therapy of pulmonary hypertension.
The Journal of laboratory and clinical medicine 2001;138(6):367-77.
2001: Schermuly R T; Roehl A; Weissmann N; Ghofrani H A; Leuchte H; Grimminger F; Seeger W; Walmrath D
Combination of nonspecific PDE inhibitors with inhaled prostacyclin in experimental pulmonary hypertension.
American journal of physiology. Lung cellular and molecular physiology 2001;281(6):L1361-8.
2001: Schermuly R T; Krupnik E; Tenor H; Schudt C; Weissmann N; Rose F; Grimminger F; Seeger W; Walmrath D; Ghofrani H A
Coaerosolization of phosphodiesterase inhibitors markedly enhances the pulmonary vasodilatory response to inhaled iloprost in experimental pulmonary hypertension. Maintenance of lung selectivity.
American journal of respiratory and critical care medicine 2001;164(9):1694-700.
2001: Olschewski H; Olschewski A; Rose F; Schermuly R; Schütte H; Weissmann N; Seeger W; Grimminger F
Physiologic basis for the treatment of pulmonary hypertension.
The Journal of laboratory and clinical medicine 2001;138(5):287-97.
2001: Schütte H; Witzenrath M; Mayer K; Rosseau S; Seeger W; Grimminger F
Short-term "preconditioning" with inhaled nitric oxide protects rabbit lungs against ischemia-reperfusion injury.
Transplantation 2001;72(8):1363-70.
2001: Wiedemann R; Ghofrani H A; Weissmann N; Schermuly R; Quanz K; Grimminger F; Seeger W; Olschewski H
Atrial natriuretic peptide in severe primary and nonprimary pulmonary hypertension: response to iloprost inhalation.
Journal of the American College of Cardiology 2001;38(4):1130-6.
2001: Schermuly R T; Weissmann N; Enke B; Ghofrani H A; Forssmann W G; Grimminger F; Seeger W; Walmrath D
Urodilatin, a natriuretic peptide stimulating particulate guanylate cyclase, and the phosphodiesterase 5 inhibitor dipyridamole attenuate experimental pulmonary hypertension: synergism upon coapplication.
American journal of respiratory cell and molecular biology 2001;25(2):219-25.
2001: Schütte H; Mayer K; Burger H; Witzenrath M; Gessler T; Seeger W; Grimminger F
Endogenous nitric oxide synthesis and vascular leakage in ischemic-reperfused rabbit lungs.
American journal of respiratory and critical care medicine 2001;164(3):412-8.
2001: Maus U; Huwe J; Maus R; Seeger W; Lohmeyer J
Alveolar JE/MCP-1 and endotoxin synergize to provoke lung cytokine upregulation, sequential neutrophil and monocyte influx, and vascular leakage in mice.
American journal of respiratory and critical care medicine 2001;164(3):406-11.
2001: Schütte H; Löckinger A; Seeger W; Grimminger F
Aerosolized PGE1, PGI2 and nitroprusside protect against vascular leakage in lung ischaemia-reperfusion.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2001;18(1):15-22.
2001: Schulz R; Olschewski H; Grimminger F; Seeger W
[Obstructive sleep apnea and cardiovascular diseases--hypothesis on the pathophysiological interlinks]
Pneumologie (Stuttgart, Germany) 2001;55(6):295-301.
2001: Hattar K; Fink L; Fietzner K; Himmel B; Grimminger F; Seeger W; Sibelius U
Cell density regulates neutrophil IL-8 synthesis: role of IL-1 receptor antagonist and soluble TNF receptors.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(10):6287-93.
2001: Ghofrani H A; Kohstall M G; Weissmann N; Schmehl T; Schermuly R T; Seeger W; Grimminger F
Alveolar epithelial barrier functions in ventilated perfused rabbit lungs.
American journal of physiology. Lung cellular and molecular physiology 2001;280(5):L896-904.
2001: Schermuly R T; Günther A; Ermert M; Ermert L; Ghofrani H A; Weissmann N; Grimminger F; Seeger W; Walmrath D
Conebulization of surfactant and urokinase restores gas exchange in perfused lungs with alveolar fibrin formation.
American journal of physiology. Lung cellular and molecular physiology 2001;280(4):L792-800.
2001: Weissmann N; Winterhalder S; Nollen M; Voswinckel R; Quanz K; Ghofrani H A; Schermuly R T; Seeger W; Grimminger F
NO and reactive oxygen species are involved in biphasic hypoxic vasoconstriction of isolated rabbit lungs.
American journal of physiology. Lung cellular and molecular physiology 2001;280(4):L638-45.
2001: Maus U; Seeger W; Lohmeyer J
Impact of a phosphorothioate oligodeoxynucleotide MCP-1 on NF-kappaB, AP-1, SP1 and NF-kappaB, and AP-1 subunit composition in human pulmonary endothelial cells.
Antisense & nucleic acid drug development 2001;11(1):59-64.
2001: Rose F; Zeller S A; Chakraborty T; Domann E; Machleidt T; Kronke M; Seeger W; Grimminger F; Sibelius U
Human endothelial cell activation and mediator release in response to Listeria monocytogenes virulence factors.
Infection and immunity 2001;69(2):897-905.
2001: Ermert L; Hocke A C; Duncker H R; Seeger W; Ermert M
Comparison of different detection methods in quantitative microdensitometry.
The American journal of pathology 2001;158(2):407-17.
2001: Gessler T; Schmehl T; Hoeper M M; Rose F; Ghofrani H A; Olschewski H; Grimminger F; Seeger W
Ultrasonic versus jet nebulization of iloprost in severe pulmonary hypertension.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2001;17(1):14-9.
2001: Löckinger A; Schütte H; Walmrath D; Seeger W; Grimminger F
Protection against gas exchange abnormalities by pre-aerosolized PGE1, iloprost and nitroprusside in lung ischemia-reperfusion.
Transplantation 2001;71(2):185-93.
2001: Schmidt R; Meier U; Yabut-Perez M; Walmrath D; Grimminger F; Seeger W; Günther A
Alteration of fatty acid profiles in different pulmonary surfactant phospholipids in acute respiratory distress syndrome and severe pneumonia.
American journal of respiratory and critical care medicine 2001;163(1):95-100.
2001: Hattar K; Sibelius U; Bickenbach A; Csernok E; Seeger W; Grimminger F
Subthreshold concentrations of anti-proteinase 3 antibodies (c-ANCA) specifically prime human neutrophils for fMLP-induced leukotriene synthesis and chemotaxis.
Journal of leukocyte biology 2001;69(1):89-97.
2001: Grandel U; Sibelius U; Schrickel J; Schmidt D; Buerke M; Fink L; Bournelis E; Heep M; Mayer K; Bohle R M; Seeger W; Grimminger F
Biosynthesis of constitutive nitric oxide synthase-derived nitric oxide attenuates coronary vasoconstriction and myocardial depression in a model of septic heart failure induced by Staphylococcus aureus alpha-toxin.
Critical care medicine 2001;29(1):1-7.
2001: Maus U; Herold S; Muth H; Maus R; Ermert L; Ermert M; Weissmann N; Rosseau S; Seeger W; Grimminger F; Lohmeyer J
Monocytes recruited into the alveolar air space of mice show a monocytic phenotype but upregulate CD14.
American journal of physiology. Lung cellular and molecular physiology 2001;280(1):L58-68.
2001: Günther A; Ruppert C; Schmidt R; Markart P; Grimminger F; Walmrath D; Seeger W
Surfactant alteration and replacement in acute respiratory distress syndrome.
Respiratory research 2001;2(6):353-64.
2000: Schulz R; Olschewski H; Grimminger F; Seeger W
[Prevalence of stroke and transitory ischemic attacks in obstructive sleep apnea: a retrospective analyis so f 187 consecutive patients]
Pneumologie (Stuttgart, Germany) 2000;54(12):575-9.
2000: Schulz R; Schmidt D; Blum A; Lopes-Ribeiro X; Lücke C; Mayer K; Olschewski H; Seeger W; Grimminger F
Decreased plasma levels of nitric oxide derivatives in obstructive sleep apnoea: response to CPAP therapy.
Thorax 2000;55(12):1046-51.
2000: Grandel U; Fink L; Blum A; Heep M; Buerke M; Kraemer H J; Mayer K; Bohle R M; Seeger W; Grimminger F; Sibelius U
Endotoxin-induced myocardial tumor necrosis factor-alpha synthesis depresses contractility of isolated rat hearts: evidence for a role of sphingosine and cyclooxygenase-2-derived thromboxane production.
Circulation 2000;102(22):2758-64.
2000: Fink L; Kinfe T; Seeger W; Ermert L; Kummer W; Bohle R M
Immunostaining for cell picking and real-time mRNA quantitation.
The American journal of pathology 2000;157(5):1459-66.
2000: Weissmann N; Tadic A; Hänze J; Rose F; Winterhalder S; Nollen M; Schermuly R T; Ghofrani H A; Seeger W; Grimminger F
Hypoxic vasoconstriction in intact lungs: a role for NADPH oxidase-derived H(2)O(2)?
American journal of physiology. Lung cellular and molecular physiology 2000;279(4):L683-90.
2000: Schütte H; Witzenrath M; Mayer K; Weissmann N; Schell A; Rosseau S; Seeger W; Grimminger F
The PDE inhibitor zaprinast enhances NO-mediated protection against vascular leakage in reperfused lungs.
American journal of physiology. Lung cellular and molecular physiology 2000;279(3):L496-502.
2000: Schulz R; Mahmoudi S; Hattar K; Sibelius U; Olschewski H; Mayer K; Seeger W; Grimminger F
Enhanced release of superoxide from polymorphonuclear neutrophils in obstructive sleep apnea. Impact of continuous positive airway pressure therapy.
American journal of respiratory and critical care medicine 2000;162(2 Pt 1):566-70.
2000: Klemm A; Tschernig T; Ermert L; Althoff A; Merkle M; Gebert A; Ermert M; Seeger W; Pabst R
Blockade of leucocyte function-associated antigen-1 (LFA-1) decreases lymphocyte trapping in the normal pulmonary vasculature: studies in the isolated buffer-perfused rat lung.
Clinical and experimental immunology 2000;121(2):375-83.
2000: Weissmann N; Voswinckel R; Tadic A; Hardebusch T; Ghofrani H A; Schermuly R T; Seeger W; Grimminger F
Nitric oxide (NO)-dependent but not NO-independent guanylate cyclase activation attenuates hypoxic vasoconstriction in rabbit lungs.
American journal of respiratory cell and molecular biology 2000;23(2):222-7.
2000: Rose F; Kiss L; Grimminger F; Mayer K; Grandel U; Seeger W; Bieniek E; Sibelius U
E. coli hemolysin-induced lipid mediator metabolism in alveolar macrophages: impact of eicosapentaenoic acid.
American journal of physiology. Lung cellular and molecular physiology 2000;279(1):L100-9.
2000: Rosseau S; Hammerl P; Maus U; Walmrath H D; Schütte H; Grimminger F; Seeger W; Lohmeyer J
Phenotypic characterization of alveolar monocyte recruitment in acute respiratory distress syndrome.
American journal of physiology. Lung cellular and molecular physiology 2000;279(1):L25-35.
2000: Rose F; Heuer K U; Sibelius U; Hombach-Klonisch S; Kiss L; Seeger W; Grimminger F
Targeting lipopolysaccharides by the nontoxic polymyxin B nonapeptide sensitizes resistant Escherichia coli to the bactericidal effect of human neutrophils.
The Journal of infectious diseases 2000;182(1):191-9.
2000: Olschewski H; Seeger W
[Treatment of pulmonary artery hypertension]
Pneumologie (Stuttgart, Germany) 2000;54(6):222-4.
2000: Maus U A; Herold S; Schlingensiepen K H; Schlingensiepen R; Dormayr T; Rosseau S; Maus R; Seeger W; Lohmeyer J
Antisense oligomers for selective suppression of MCP-1 synthesis in human pulmonary endothelial cells.
Antisense & nucleic acid drug development 2000;10(3):185-93.
2000: Günther A; Mosavi P; Ruppert C; Heinemann S; Temmesfeld B; Velcovsky H G; Morr H; Grimminger F; Walmrath D; Seeger W
Enhanced tissue factor pathway activity and fibrin turnover in the alveolar compartment of patients with interstitial lung disease.
Thrombosis and haemostasis 2000;83(6):853-60.
2000: Kiss L; Schütte H; Mayer K; Grimm H; Padberg W; Seeger W; Grimminger F
Synthesis of arachidonic acid-derived lipoxygenase and cytochrome P450 products in the intact human lung vasculature.
American journal of respiratory and critical care medicine 2000;161(6):1917-23.
2000: Ermert M; Merkle M; Mootz R; Grimminger F; Seeger W; Ermert L
Endotoxin priming of the cyclooxygenase-2-thromboxane axis in isolated rat lungs.
American journal of physiology. Lung cellular and molecular physiology 2000;278(6):L1195-203.
2000: Ermert L; Ermert M; Merkle M; Goppelt-Struebe M; Duncker H R; Grimminger F; Seeger W
Rat pulmonary cyclooxygenase-2 expression in response to endotoxin challenge: differential regulation in the various types of cells in the lung.
The American journal of pathology 2000;156(4):1275-87.
2000: Ermert L; Ermert M; Duncker H R; Grimminger F; Seeger W
In situ localization and regulation of thromboxane A(2) synthase in normal and LPS-primed lungs.
American journal of physiology. Lung cellular and molecular physiology 2000;278(4):L744-53.
2000: Fink L; Kinfe T; Stein M M; Ermert L; Hänze J; Kummer W; Seeger W; Bohle R M
Immunostaining and laser-assisted cell picking for mRNA analysis.
Laboratory investigation; a journal of technical methods and pathology 2000;80(3):327-33.
2000: Olschewski H; Ghofrani H A; Schmehl T; Winkler J; Wilkens H; Höper M M; Behr J; Kleber F X; Seeger W
Inhaled iloprost to treat severe pulmonary hypertension. An uncontrolled trial. German PPH Study Group.
Annals of internal medicine 2000;132(6):435-43.
2000: Günther A; Mosavi P; Heinemann S; Ruppert C; Muth H; Markart P; Grimminger F; Walmrath D; Temmesfeld-Wollbrück B; Seeger W
Alveolar fibrin formation caused by enhanced procoagulant and depressed fibrinolytic capacities in severe pneumonia. Comparison with the acute respiratory distress syndrome.
American journal of respiratory and critical care medicine 2000;161(2 Pt 1):454-62.
2000: Grimminger F; Mayer K; Kiss L; Walmrath D; Seeger W
PAF-induced synthesis of tetraenoic and pentaenoic leukotrienes in the isolated rabbit lung.
American journal of physiology. Lung cellular and molecular physiology 2000;278(2):L268-75.
2000: Schermuly R T; Roehl A; Weissmann N; Ghofrani H A; Schudt C; Tenor H; Grimminger F; Seeger W; Walmrath D
Subthreshold doses of specific phosphodiesterase type 3 and 4 inhibitors enhance the pulmonary vasodilatory response to nebulized prostacyclin with improvement in gas exchange.
The Journal of pharmacology and experimental therapeutics 2000;292(2):512-20.
2000: Schermuly R T; Günther A; Weissmann N; Ghofrani H A; Seeger W; Grimminger F; Walmrath D
Differential impact of ultrasonically nebulized versus tracheal-instilled surfactant on ventilation-perfusion (VA/Q) mismatch in a model of acute lung injury.
American journal of respiratory and critical care medicine 2000;161(1):152-9.
2000: Sibelius U; Grandel U; Buerke M; Mueller D; Kiss L; Kraemer H J; Braun-Dullaeus R; Haberbosch W; Seeger W; Grimminger F
Staphylococcal alpha-toxin provokes coronary vasoconstriction and loss in myocardial contractility in perfused rat hearts: role of thromboxane generation.
Circulation 2000;101(1):78-85.
2000: Rosseau S; Selhorst J; Wiechmann K; Leissner K; Maus U; Mayer K; Grimminger F; Seeger W; Lohmeyer J
Monocyte migration through the alveolar epithelial barrier: adhesion molecule mechanisms and impact of chemokines.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(1):427-35.
2000: Bohle R M; Hartmann E; Kinfe T; Ermert L; Seeger W; Fink L
Cell type-specific mRNA quantitation in non-neoplastic tissues after laser-assisted cell picking.
Pathobiology : journal of immunopathology, molecular and cellular biology 2000;68(4-5):191-5.
1999: Seeger W
[Pneumology. From the diagnosis of pulmonary functions to molecular medicine]
Deutsche medizinische Wochenschrift (1946) 1999;124(51-52):1566-9.
1999: Günther A; Markart P; Kalinowski M; Ruppert C; Grimminger F; Seeger W
Cleavage of surfactant-incorporating fibrin by different fibrinolytic agents. Kinetics of lysis and rescue of surface activity.
American journal of respiratory cell and molecular biology 1999;21(6):738-45.
1999: Schermuly R T; Ghofrani H A; Enke B; Weissmann N; Grimminger F; Seeger W; Schudt C; Walmrath D
Low-dose systemic phosphodiesterase inhibitors amplify the pulmonary vasodilatory response to inhaled prostacyclin in experimental pulmonary hypertension.
American journal of respiratory and critical care medicine 1999;160(5 Pt 1):1500-6.
1999: Rosseau S; Hammerl P; Maus U; Günther A; Seeger W; Grimminger F; Lohmeyer J
Surfactant protein A down-regulates proinflammatory cytokine production evoked by Candida albicans in human alveolar macrophages and monocytes.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(8):4495-502.
1999: Hermle G; Schütte H; Walmrath D; Geiger K; Seeger W; Grimminger F
Ventilation-perfusion mismatch after lung ischemia-reperfusion. Protective effect of nitric oxide.
American journal of respiratory and critical care medicine 1999;160(4):1179-87.
1999: Mayer K; Temmesfeld-Wollbrück B; Friedland A; Olschewski H; Reich M; Seeger W; Grimminger A F
Severe microcirculatory abnormalities elicited by E. coli hemolysin in the rabbit ileum mucosa.
American journal of respiratory and critical care medicine 1999;160(4):1171-8.
1999: Günther A; Schmidt R; Nix F; Yabut-Perez M; Guth C; Rosseau S; Siebert C; Grimminger F; Morr H; Velcovsky H G; Seeger W
Surfactant abnormalities in idiopathic pulmonary fibrosis, hypersensitivity pneumonitis and sarcoidosis.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1999;14(3):565-73.
1999: Rose F; Zwick K; Ghofrani H A; Sibelius U; Seeger W; Walmrath D; Grimminger F
Prostacyclin enhances stretch-induced surfactant secretion in alveolar epithelial type II cells.
American journal of respiratory and critical care medicine 1999;160(3):846-51.
1999: Olschewski H; Ghofrani H A; Walmrath D; Schermuly R; Temmesfeld-Wollbruck B; Grimminger F; Seeger W
Inhaled prostacyclin and iloprost in severe pulmonary hypertension secondary to lung fibrosis.
American journal of respiratory and critical care medicine 1999;160(2):600-7.
1999: Grimminger F; Olschewski H; Seeger W
[Vasotropic therapy and artificial respiration for pulmonary hypertension]
Der Internist 1999;40(7):747-55.
1999: Olschewski H; Seeger W; Grimminger F
[Physiology and physiopathology of the pulmonary circulation]
Der Internist 1999;40(7):696-709.
1999: Lohmeyer J; Friedrich J; Grimminger F; Maus U; Tenter R; Morr H; Velcovsky H G; Seeger W; Rosseau S
Expression of mucosa-related integrin alphaEbeta7 on alveolar T cells in interstitial lung diseases.
Clinical and experimental immunology 1999;116(2):340-6.
1999: Seeger W
[Pneumology]
Der Internist 1999;40(4):391-400.
1999: Fink L; Stahl U; Ermert L; Kummer W; Seeger W; Bohle R M
Rat porphobilinogen deaminase gene: a pseudogene-free internal standard for laser-assisted cell picking.
BioTechniques 1999;26(3):510-6.
1999: Sibelius U; Schulz E C; Rose F; Hattar K; Jacobs T; Weiss S; Chakraborty T; Seeger W; Grimminger F
Role of Listeria monocytogenes exotoxins listeriolysin and phosphatidylinositol-specific phospholipase C in activation of human neutrophils.
Infection and immunity 1999;67(3):1125-30.
1999: Maus U; Rosseau S; Mandrakas N; Schlingensiepen R; Maus R; Muth H; Grimminger F; Seeger W; Lohmeyer J
Cationic lipids employed for antisense oligodeoxynucleotide transport may inhibit vascular cell adhesion molecule-1 expression in human endothelial cells: a word of caution.
Antisense & nucleic acid drug development 1999;9(1):71-80.
1999: Weissmann N; Voswinckel R; Hardebusch T; Rosseau S; Ghofrani H A; Schermuly R; Seeger W; Grimminger F
Evidence for a role of protein kinase C in hypoxic pulmonary vasoconstriction.
The American journal of physiology 1999;276(1 Pt 1):L90-5.
1999: Günther A; Schmidt R; Feustel A; Meier U; Pucker C; Ermert M; Seeger W
Surfactant subtype conversion is related to loss of surfactant apoprotein B and surface activity in large surfactant aggregates. Experimental and clinical studies.
American journal of respiratory and critical care medicine 1999;159(1):244-51.
1998: Grimm H; Grimminger F; Korom S; Seeger W
Use of fish oil to prevent graft rejection.
The Proceedings of the Nutrition Society 1998;57(4):577-85.
1998: Weissmann N; Seeger W; Conzen J; Kiss L; Grimminger F
Effects of arachidonic acid metabolism on hypoxic vasoconstriction in rabbit lungs.
European journal of pharmacology 1998;356(2-3):231-7.
1998: Ermert L; Ermert M; Althoff A; Merkle M; Grimminger F; Seeger W
Vasoregulatory prostanoid generation proceeds via cyclooxygenase-2 in noninflamed rat lungs.
The Journal of pharmacology and experimental therapeutics 1998;286(3):1309-14.
1998: Kiss L; Bieniek E; Weissmann N; Schutte H; Sibelius U; Gunther A; Bier J; Mayer K; Henneking K; Padberg W; Grimm H; Seeger W; Grimminger F
Simultaneous analysis of 4- and 5-series lipoxygenase and cytochrome P450 products from different biological sources by reversed-phase high-performance liquid chromatographic technique.
Analytical biochemistry 1998;261(1):16-28.
1998: Glocker F X; Krauss J K; Deuschl G; Seeger W; Lücking C H
Hemifacial spasm due to posterior fossa tumors: the impact of tumor location on electrophysiological findings.
Clinical neurology and neurosurgery 1998;100(2):104-11.
1998: Olschewski H; Ghofrani H A; Walmrath D; Temmesfeld-Wollbrück B; Grimminger F; Seeger W
Recovery from circulatory shock in severe primary pulmonary hypertension (PPH) with aerosolization of iloprost.
Intensive care medicine 1998;24(6):631-4.
1998: Weissmann N; Grimminger F; Voswinckel R; Conzen J; Seeger W
Nitro blue tetrazolium inhibits but does not mimic hypoxic vasoconstriction in isolated rabbit lungs.
The American journal of physiology 1998;274(5 Pt 1):L721-7.
1998: Temmesfeld-Wollbrück B; Szalay A; Mayer K; Olschewski H; Seeger W; Grimminger F
Abnormalities of gastric mucosal oxygenation in septic shock: partial responsiveness to dopexamine.
American journal of respiratory and critical care medicine 1998;157(5 Pt 1):1586-92.
1998: Mayser P; Mrowietz U; Arenberger P; Bartak P; Buchvald J; Christophers E; Jablonska S; Salmhofer W; Schill W B; Krämer H J; Schlotzer E; Mayer K; Seeger W; Grimminger F
Omega-3 fatty acid-based lipid infusion in patients with chronic plaque psoriasis: results of a double-blind, randomized, placebo-controlled, multicenter trial.
Journal of the American Academy of Dermatology 1998;38(4):539-47.
1998: Ermert L; Ermert M; Goppelt-Struebe M; Walmrath D; Grimminger F; Steudel W; Ghofrani H A; Homberger C; Duncker H; Seeger W
Cyclooxygenase isoenzyme localization and mRNA expression in rat lungs.
American journal of respiratory cell and molecular biology 1998;18(4):479-88.
1998: Mayer K; Seeger W; Grimminger F
Clinical use of lipids to control inflammatory disease.
Current opinion in clinical nutrition and metabolic care 1998;1(2):179-84.
1998: Maus U; Rosseau S; Knies U; Seeger W; Lohmeyer J
Expression of pro-inflammatory cytokines by flow-sorted alveolar macrophages in severe pneumonia.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1998;11(3):534-41.
1998: Schütte H; Mayer K; Gessler T; Rühl M; Schlaudraff J; Burger H; Seeger W; Grimminger F
Nitric oxide biosynthesis in an exotoxin-induced septic lung model: role of cNOS and impact on pulmonary hemodynamics.
American journal of respiratory and critical care medicine 1998;157(2):498-504.
1998: Sibelius U; Hattar K; Schenkel A; Noll T; Csernok E; Gross W L; Mayet W J; Piper H M; Seeger W; Grimminger F
Wegener's granulomatosis: anti-proteinase 3 antibodies are potent inductors of human endothelial cell signaling and leakage response.
The Journal of experimental medicine 1998;187(4):497-503.
1998: Olschewski H; Walmrath D; Schermuly R; Ghofrani H A; Grimminger F; Seeger W
[Prostacyclin and iloprost in aerosol form in severe pulmonary hypertension]
Pneumologie (Stuttgart, Germany) 1998;52(1):3-7.
1998: Schütte H; Hermle G; Seeger W; Grimminger F
Vascular distension and continued ventilation are protective in lung ischemia/reperfusion.
American journal of respiratory and critical care medicine 1998;157(1):171-7.
1997: Schütte H; Rosseau S; Czymek R; Ermert L; Walmrath D; Krämer H J; Seeger W; Grimminger F
Synergism between endotoxin priming and exotoxin challenge in provoking severe vascular leakage in rabbit lungs.
American journal of respiratory and critical care medicine 1997;156(3 Pt 1):819-24.
1997: Schermuly R; Schmehl T; Günther A; Grimminger F; Seeger W; Walmrath D
Ultrasonic nebulization for efficient delivery of surfactant in a model of acute lung injury. Impact on gas exchange.
American journal of respiratory and critical care medicine 1997;156(2 Pt 1):445-53.
1997: Schütte H; Grimminger F; Otterbein J; Spriestersbach R; Mayer K; Walmrath D; Seeger W
Efficiency of aerosolized nitric oxide donor drugs to achieve sustained pulmonary vasodilation.
The Journal of pharmacology and experimental therapeutics 1997;282(2):985-94.
1997: Grimminger F; Rose F; Sibelius U; Meinhardt M; Pötzsch B; Spriestersbach R; Bhakdi S; Suttorp N; Seeger W
Human endothelial cell activation and mediator release in response to the bacterial exotoxins Escherichia coli hemolysin and staphylococcal alpha-toxin.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(4):1909-16.
1997: Steudel W; Krämer H J; Degner D; Rosseau S; Schütte H; Walmrath D; Seeger W
Endotoxin priming of thromboxane-related vasoconstrictor responses in perfused rabbit lungs.
Journal of applied physiology (Bethesda, Md. : 1985) 1997;83(1):18-24.
1997: Grimminger F; Mayer K; Seeger W
[Is there a reliable immunotherapy in infection?]
Der Internist 1997;38(6):541-52.
1997: Walmrath D; Olschewski H; Grimminger F; Seeger W
[NO and alternative inhalational therapy approaches in pulmonary hypertension]
Der Internist 1997;38(5):453-60.
1997: Walmrath D; Schermuly R; Pilch J; Grimminger F; Seeger W
Effects of inhaled versus intravenous vasodilators in experimental pulmonary hypertension.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1997;10(5):1084-92.
1997: Krauss J K; Seeger W; Jankovic J
Cervical dystonia associated with tumors of the posterior fossa.
Movement disorders : official journal of the Movement Disorder Society 1997;12(3):443-7.
1997: Temmesfeld-Wollbrueck B; Heinrichs C; Szalay A; Seeger W
Granulomatous gastritis in Wegener's disease: differentiation from Crohn's disease supported by a positive test for antineutrophil antibodies.
Gut 1997;40(4):550-3.
1997: Temmesfeld-Wollbrück B; Szalay A; Olschewski H; Grimminger F; Seeger W
Advantage of buffered solutions or automated capnometry in air-filled balloons for use in gastric tonometry.
Intensive care medicine 1997;23(4):423-7.
1997: Maus U; Rosseau S; Seeger W; Lohmeyer J
Separation of human alveolar macrophages by flow cytometry.
The American journal of physiology 1997;272(3 Pt 1):L566-71.
1997: Grimminger F; Mayer K; Kiss L; Wahn H; Walmrath D; Seeger W
Synthesis of 4- and 5-series leukotrienes in the lung microvasculature challenged with Escherichia coli hemolysin: critical dependence on exogenous free fatty acid supply.
American journal of respiratory cell and molecular biology 1997;16(3):317-24.
1997: Rosseau S; Guenther A; Seeger W; Lohmeyer J
Phagocytosis of viable Candida albicans by alveolar macrophages: lack of opsonin function of surfactant protein A.
The Journal of infectious diseases 1997;175(2):421-8.
1997: Ermert L; Duncker H R; Brückner H; Grimminger F; Hansen T; Rössig R; Aktories K; Seeger W
Ultrastructural changes of lung capillary endothelium in response to botulinum C2 toxin.
Journal of applied physiology (Bethesda, Md. : 1985) 1997;82(2):382-8.
1997: Grimminger F; Wahn H; Mayer K; Kiss L; Walmrath D; Seeger W
Impact of arachidonic versus eicosapentaenoic acid on exotonin-induced lung vascular leakage: relation to 4-series versus 5-series leukotriene generation.
American journal of respiratory and critical care medicine 1997;155(2):513-9.
1996: Sibelius U; Chakraborty T; Krögel B; Wolf J; Rose F; Schmidt R; Wehland J; Seeger W; Grimminger F
The listerial exotoxins listeriolysin and phosphatidylinositol-specific phospholipase C synergize to elicit endothelial cell phosphoinositide metabolism.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(9):4055-60.
1996: Krämer H J; Stevens J; Grimminger F; Seeger W
Fish oil fatty acids and human platelets: dose-dependent decrease in dienoic and increase in trienoic thromboxane generation.
Biochemical pharmacology 1996;52(8):1211-7.
1996: Grimminger F; Hattar K; Papavassilis C; Temmesfeld B; Csernok E; Gross W L; Seeger W; Sibelius U
Neutrophil activation by anti-proteinase 3 antibodies in Wegener's granulomatosis: role of exogenous arachidonic acid and leukotriene B4 generation.
The Journal of experimental medicine 1996;184(4):1567-72.
1996: Schütte H; Lohmeyer J; Rosseau S; Ziegler S; Siebert C; Kielisch H; Pralle H; Grimminger F; Morr H; Seeger W
Bronchoalveolar and systemic cytokine profiles in patients with ARDS, severe pneumonia and cardiogenic pulmonary oedema.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1996;9(9):1858-67.
1996: Krauss J K; Droste D W; Vach W; Regel J P; Orszagh M; Borremans J J; Tietz A; Seeger W
Cerebrospinal fluid shunting in idiopathic normal-pressure hydrocephalus of the elderly: effect of periventricular and deep white matter lesions.
Neurosurgery 1996;39(2):292-9; discussion 299-300.
1996: Walmrath D; Ghofrani H A; Grimminger F; Seeger W
Synergism of alveolar endotoxin "priming" and intravascular exotoxin challenge in lung injury.
American journal of respiratory and critical care medicine 1996;154(2 Pt 1):460-8.
1996: Borremans J J; Krauss J K; Fanardjian R V; Seeger W
Hemichorea-hemiballism associated with an ipsilateral intraventricular cyst after resection of a meningioma.
Parkinsonism & related disorders 1996;2(3):155-9.
1996: Walmrath D; Günther A; Ghofrani H A; Schermuly R; Schneider T; Grimminger F; Seeger W
Bronchoscopic surfactant administration in patients with severe adult respiratory distress syndrome and sepsis.
American journal of respiratory and critical care medicine 1996;154(1):57-62.
1996: Bux J; Becker F; Seeger W; Kilpatrick D; Chapman J; Waters A
Transfusion-related acute lung injury due to HLA-A2-specific antibodies in recipient and NB1-specific antibodies in donor blood.
British journal of haematology 1996;93(3):707-13.
1996: Olschewski H; Walmrath D; Schermuly R; Ghofrani A; Grimminger F; Seeger W
Aerosolized prostacyclin and iloprost in severe pulmonary hypertension.
Annals of internal medicine 1996;124(9):820-4.
1996: Walmrath D; Schneider T; Schermuly R; Olschewski H; Grimminger F; Seeger W
Direct comparison of inhaled nitric oxide and aerosolized prostacyclin in acute respiratory distress syndrome.
American journal of respiratory and critical care medicine 1996;153(3):991-6.
1996: Sibelius U; Rose F; Chakraborty T; Darji A; Wehland J; Weiss S; Seeger W; Grimminger F
Listeriolysin is a potent inducer of the phosphatidylinositol response and lipid mediator generation in human endothelial cells.
Infection and immunity 1996;64(2):674-6.
1996: Schmehl T; Gebhart J; Schütte H; Scharmann A; Seeger W
On-line laser-photometric monitoring of aerosol deposition in ventilated rabbit lungs.
Journal of applied physiology (Bethesda, Md. : 1985) 1996;80(1):351-6.
1996: Ermert L; Rössig R; Hansen T; Schütte H; Aktories K; Seeger W
Differential role of actin in lung endothelial and epithelial barrier properties in perfused rabbit lungs.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1996;9(1):93-9.
1996: Ghofrani H A; Rosseau S; Walmrath D; Kaddus W; Kramer A; Grimminger F; Lohmeyer J; Seeger W
Compartmentalized lung cytokine release in response to intravascular and alveolar endotoxin challenge.
The American journal of physiology 1996;270(1 Pt 1):L62-8.
1996: Grimminger F; Grimm H; Führer D; Papavassilis C; Lindemann G; Blecher C; Mayer K; Tabesch F; Krämer H J; Stevens J; Seeger W
Omega-3 lipid infusion in a heart allotransplant model. Shift in fatty acid and lipid mediator profiles and prolongation of transplant survival.
Circulation 1996;93(2):365-71.
1996: Günther A; Siebert C; Schmidt R; Ziegler S; Grimminger F; Yabut M; Temmesfeld B; Walmrath D; Morr H; Seeger W
Surfactant alterations in severe pneumonia, acute respiratory distress syndrome, and cardiogenic lung edema.
American journal of respiratory and critical care medicine 1996;153(1):176-84.
1996: Bertalanffy H; Gilsbach J M; Mayfrank L; Klein H M; Kawase T; Seeger W
Microsurgical management of ventral and ventrolateral foramen magnum meningiomas.
Acta neurochirurgica. Supplement 1996;65():82-5.
1995: Krauss J K; Wakhloo A K; Nobbe F; Tränkle R; Mundinger F; Seeger W
Lesion of dentatothalamic pathways in severe post-traumatic tremor.
Neurological research 1995;17(6):409-16.
1995: Seeger W; Walmrath D; Grimminger F
[New supportive therapy measures in acute lung failure]
Der Internist 1995;36(12):1139-49.
1995: Günther A; Kalinowski M; Rosseau S; Seeger W
Surfactant incorporation markedly alters mechanical properties of a fibrin clot.
American journal of respiratory cell and molecular biology 1995;13(6):712-8.
1995: Krämer H J; Schmidt R; Günther A; Becker G; Suzuki Y; Seeger W
ELISA technique for quantification of surfactant protein B (SP-B) in bronchoalveolar lavage fluid.
American journal of respiratory and critical care medicine 1995;152(5 Pt 1):1540-4.
1995: Seeger W; Walmrath D; Grimminger F
[ARDS. Intensive therapy of acute lung failure]
Der Internist 1995;36(8):785-801.
1995: Seeger W; Hansen T; Rössig R; Schmehl T; Schütte H; Krämer H J; Walmrath D; Weissmann N; Grimminger F; Suttorp N
Hydrogen peroxide-induced increase in lung endothelial and epithelial permeability--effect of adenylate cyclase stimulation and phosphodiesterase inhibition.
Microvascular research 1995;50(1):1-17.
1995: Grimminger F; Wahn H; Kramer H J; Stevens J; Mayer K; Walmrath D; Seeger W
Differential influence of arachidonic vs. eicosapentaenoic acid on experimental pulmonary hypertension.
The American journal of physiology 1995;268(6 Pt 2):H2252-9.
1995: Ermert L; Brückner H; Walmrath D; Grimminger F; Aktories K; Suttorp N; Duncker H R; Seeger W
Role of endothelial cytoskeleton in high-permeability edema due to botulinum C2 toxin in perfused rabbit lungs.
The American journal of physiology 1995;268(5 Pt 1):L753-61.
1995: Grimminger F; Weissmann N; Spriestersbach R; Becker E; Rosseau S; Seeger W
Effects of NADPH oxidase inhibitors on hypoxic vasoconstriction in buffer-perfused rabbit lungs.
The American journal of physiology 1995;268(5 Pt 1):L747-52.
1995: Weissmann N; Grimminger F; Walmrath D; Seeger W
Hypoxic vasoconstriction in buffer-perfused rabbit lungs.
Respiration physiology 1995;100(2):159-69.
1995: Seeger W; Lasch H G
[Respiratory insufficiency]
Der Internist 1995;36(4):318-26.
1995: Grimminger F; Spriestersbach R; Weissmann N; Walmrath D; Seeger W
Nitric oxide generation and hypoxic vasoconstriction in buffer-perfused rabbit lungs.
Journal of applied physiology (Bethesda, Md. : 1985) 1995;78(4):1509-15.
1995: Spriestersbach R; Grimminger F; Weissmann N; Walmrath D; Seeger W
On-line measurement of nitric oxide generation in buffer-perfused rabbit lungs.
Journal of applied physiology (Bethesda, Md. : 1985) 1995;78(4):1502-8.
1995: Walmrath D; Schneider T; Pilch J; Schermuly R; Grimminger F; Seeger W
Effects of aerosolized prostacyclin in severe pneumonia. Impact of fibrosis.
American journal of respiratory and critical care medicine 1995;151(3 Pt 1):724-30.
1995: Schmolling J; Seeger W; Jensen A
Liquid movements in ventilated and perfused isolated lungs of fetal sheep at 0.87, 0.90, and 0.95 of term.
Reproduction, fertility, and development 1995;7(5):1345-50.
1995: Krauss J K; Droste D W; Bohus M; Regel J P; Scheremet R; Riemann D; Seeger W
The relation of intracranial pressure B-waves to different sleep stages in patients with suspected normal pressure hydrocephalus.
Acta neurochirurgica 1995;136(3-4):195-203.
1995: Sure U; Bertalanffy H; Isenmann S; Brandner S; Berghorn W J; Seeger W; Aguzzi A
Secondary manifestation of medulloblastoma: metastases and local recurrences in 66 patients.
Acta neurochirurgica 1995;136(3-4):117-26.
1995: Krauss J K; Paduch T; Mundinger F; Seeger W
Parkinsonism and rest tremor secondary to supratentorial tumours sparing the basal ganglia.
Acta neurochirurgica 1995;133(1-2):22-9.
1995: Sure U; Berghorn W J; Bertalanffy H; Wakabayashi T; Yoshida J; Sugita K; Seeger W
Staging, scoring and grading of medulloblastoma. A postoperative prognosis predicting system based on the cases of a single institute.
Acta neurochirurgica 1995;132(1-3):59-65.
1995: Temmesfeld-Wollbrück B; Walmrath D; Grimminger F; Seeger W
Prevention and therapy of the adult respiratory distress syndrome.
Lung 1995;173(3):139-64.
1994: Günther A; Kalinowski M; Elssner A; Seeger W
Clot-embedded natural surfactant: kinetics of fibrinolysis and surface activity.
The American journal of physiology 1994;267(5 Pt 1):L618-24.
1994: Walmrath D; Ghofrani H A; Rosseau S; Schütte H; Cramer A; Kaddus W; Grimminger F; Bhakdi S; Seeger W
Endotoxin "priming" potentiates lung vascular abnormalities in response to Escherichia coli hemolysin: an example of synergism between endo- and exotoxin.
The Journal of experimental medicine 1994;180(4):1437-43.
1994: Rosseau S; Seeger W; Pralle H; Lohmeyer J
Phagocytosis of viable Candida albicans by alveolar macrophages: flow cytometric quantification.
The American journal of physiology 1994;267(2 Pt 1):L211-7.
1994: Ermert L; Duncker H R; Rosseau S; Schütte H; Seeger W
Morphometric analysis of pulmonary intracapillary leukocyte pools in ex vivo-perfused rabbit lungs.
The American journal of physiology 1994;267(1 Pt 1):L64-70.
1994: Lohmeyer J; Friedrich J; Rosseau S; Pralle H; Seeger W
Multiparameter flow cytometric analysis of inflammatory cells contained in bronchoalveolar lavage fluid.
Journal of immunological methods 1994;172(1):59-70.
1994: Walmrath D; Pilch J; Scharmann M; Grimminger F; Seeger W
Severe VA/Q mismatch in perfused lungs evoked by sequential challenge with endotoxin and E. coli hemolysin.
Journal of applied physiology (Bethesda, Md. : 1985) 1994;76(3):1020-30.
1994: Seeger W; Walmrath D; Grimminger F; Rosseau S; Schütte H; Krämer H J; Ermert L; Kiss L
Adult respiratory distress syndrome: model systems using isolated perfused rabbit lungs.
Methods in enzymology 1994;233():549-84.
1993: Walmrath D; Griebner M; Kolb B; Grimminger F; Galanos C; Schade U; Seeger W
Endotoxin primes perfused rabbit lungs for enhanced vasoconstrictor response to staphylococcal alpha-toxin.
The American review of respiratory disease 1993;148(5):1179-86.
1993: Temmesfeld-Wollbrück B; Morr H; Suttorp N; Altmannsberger M; Seeger W
[Three cases of a fulminant course of idiopathic pulmonary fibrosis (Hamman-Rich syndrome)]
Pneumologie (Stuttgart, Germany) 1993;47(10):573-8.
1993: Grimminger F; Mayer K; Krämer H J; Stevens J; Walmrath D; Seeger W
Differential vasoconstrictor potencies of free fatty acids in the lung vasculature: 2-versus 3-series prostanoid generation.
The Journal of pharmacology and experimental therapeutics 1993;267(1):259-65.
1993: Walmrath D; Schneider T; Pilch J; Grimminger F; Seeger W
Aerosolised prostacyclin in adult respiratory distress syndrome.
Lancet 1993;342(8877):961-2.
1993: Seeger W; Grube C; Günther A
Proteolytic cleavage of fibrinogen: amplification of its surfactant inhibitory capacity.
American journal of respiratory cell and molecular biology 1993;9(3):239-47.
1993: Günther A; Bleyl H; Seeger W
Apoprotein-based synthetic surfactants inhibit plasmic cleavage of fibrinogen in vitro.
The American journal of physiology 1993;265(2 Pt 1):L186-92.
1993: Seeger W; Elssner A; Günther A; Krämer H J; Kalinowski H O
Lung surfactant phospholipids associate with polymerizing fibrin: loss of surface activity.
American journal of respiratory cell and molecular biology 1993;9(2):213-20.
1993: Seeger W; Grube C; Günther A; Schmidt R
Surfactant inhibition by plasma proteins: differential sensitivity of various surfactant preparations.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1993;6(7):971-7.
1993: Krauss J K; Wakhloo A K; Scheremet R; Seeger W
Facial myokymia and spastic paretic facial contracture as the result of anaplastic pontocerebellar glioma.
Neurosurgery 1993;32(6):1031-4.
1993: Bertalanffy H; Bechtel S; Seeger W
Regional exposure of cerebral convexity lesions.
Neurochirurgia 1993;36(3):81-6.
1993: Seeger W
[Prevention of acute lung failure (ARDS)]
Medizinische Klinik (Munich, Germany : 1983) 1993;88(4):231-46.
1993: Walmrath D; Scharmann M; König R; Pilch J; Grimminger F; Seeger W
Staphylococcal alpha-toxin induced ventilation-perfusion mismatch in isolated blood-free perfused rabbit lungs.
Journal of applied physiology (Bethesda, Md. : 1985) 1993;74(4):1972-80.
1993: Krauss J K; Bertalanffy H; Schwechheimer K; Müller A; Seeger W
Ventral brain stem schwannoma at the entry zone of the hypoglossal nerve.
Neurochirurgia 1993;36(2):66-9.
1993: Seeger W; Günther A; Walmrath H D; Grimminger F; Lasch H G
Alveolar surfactant and adult respiratory distress syndrome. Pathogenetic role and therapeutic prospects.
The Clinical investigator 1993;71(3):177-90.
1993: Ermert L; Seeger W; Duncker H R
Computer-assisted morphometry of the intracapillary leukocyte pool in the rabbit lung.
Cell and tissue research 1993;271(3):469-76.
1992: Seeger W; Grimminger F; Walmrath D
[ARDS: possible role of bacterial exotoxin]
Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS 1992;27(5):310-4.
1992: Bertalanffy H; Kühn G; Scheremet R; Seeger W
Indications for surgery and prognosis in patients with cerebral cavernous angiomas.
Neurologia medico-chirurgica 1992;32(9):659-66.
1992: Grimminger F; Dürr U; Seeger W
Ligand-operated synthesis of 4-series and 5-series leukotrienes in human neutrophils: critical dependence on exogenous free fatty acid supply.
Molecular pharmacology 1992;41(4):757-66.
1992: Seeger W; Günther A; Thede C
Differential sensitivity to fibrinogen inhibition of SP-C- vs. SP-B-based surfactants.
The American journal of physiology 1992;262(3 Pt 1):L286-91.
1992: Ermert L; Rousseau S; Schütte H; Birkemeyer R G; Grimminger F; Bhakdi S; Duncker H R; Seeger W
Induction of severe vascular leakage by low doses of Escherichia coli hemolysin in perfused rabbit lungs.
Laboratory investigation; a journal of technical methods and pathology 1992;66(3):362-9.
1992: Grimminger F; von Kürten I; Walmrath D; Seeger W
Type II alveolar epithelial eicosanoid metabolism: predominance of cyclooxygenase pathways and transcellular lipoxygenase metabolism in co-culture with neutrophils.
American journal of respiratory cell and molecular biology 1992;6(1):9-16.
1992: Walmrath D; König R; Ernst C; Brückner H; Grimminger F; Seeger W
Ventilation-perfusion relationships in isolated blood-free perfused rabbit lungs.
Journal of applied physiology (Bethesda, Md. : 1985) 1992;72(1):374-82.
1992: Laborde G; Gilsbach J M; Harders A; Seeger W
Experience with the infratentorial supracerebellar approach in lesions of the quadrigeminal region, posterior third ventricle, culmen cerebelli, and cerebellar peduncle.
Acta neurochirurgica 1992;114(3-4):135-8.
1991: Bertalanffy H; Seeger W
The dorsolateral, suboccipital, transcondylar approach to the lower clivus and anterior portion of the craniocervical junction.
Neurosurgery 1991;29(6):815-21.
1991: Walmrath D; Schneider U; Kreusler B; Grimminger F; Ennis M; Seeger W
Intravascular anti-IgE challenge in perfused lungs: mediator release and vascular pressor response.
Journal of applied physiology (Bethesda, Md. : 1985) 1991;71(6):2499-506.
1991: Grimminger F; Sibelius U; Bhakdi S; Suttorp N; Seeger W
Escherichia coli hemolysin is a potent inductor of phosphoinositide hydrolysis and related metabolic responses in human neutrophils.
The Journal of clinical investigation 1991;88(5):1531-9.
1991: Schütte H; Rosseau S; Walmrath D; Grimminger F; Ernst C; Seeger W
Neutrophil passage through isolated perfused rabbit lungs.
The American journal of physiology 1991;261(4 Pt 2):H1317-23.
1991: Grimminger F; Sibelius U; Aktories K; Suttorp N; Seeger W
Inhibition of cytoskeletal rearrangement by botulinum C2 toxin amplifies ligand-evoked lipid mediator generation in human neutrophils.
Molecular pharmacology 1991;40(4):563-71.
1991: Grimminger F; Sibelius U; Aktories K; Just I; Seeger W
Suppression of cytoskeletal rearrangement in activated human neutrophils by botulinum C2 toxin. Impact on cellular signal transduction.
The Journal of biological chemistry 1991;266(29):19276-82.
1991: Grimminger F; Scholz C; Bhakdi S; Seeger W
Subhemolytic doses of Escherichia coli hemolysin evoke large quantities of lipoxygenase products in human neutrophils.
The Journal of biological chemistry 1991;266(22):14262-9.
1991: Grimminger F; Sibelius U; Seeger W
Amplification of LTB4 generation in AM-PMN cocultures: transcellular 5-lipoxygenase metabolism.
The American journal of physiology 1991;261(2 Pt 1):L195-203.
1991: Suttorp N; Polley M; Seybold J; Schnittler H; Seeger W; Grimminger F; Aktories K
Adenosine diphosphate-ribosylation of G-actin by botulinum C2 toxin increases endothelial permeability in vitro.
The Journal of clinical investigation 1991;87(5):1575-84.
1991: Seeger W; Obernitz R; Thomas M; Walmrath D; Suttorn N; Holland I B; Grimminger F; Eberspächer B; Hugo F; Bhakdi S
Lung vascular injury after administration of viable hemolysin-forming Escherichia coli in isolated rabbit lungs.
The American review of respiratory disease 1991;143(4 Pt 1):797-805.
1991: Grimminger F; Kreusler B; Schneider U; von Witzleben E; Walmrath D; Neppert J; Seeger W
Human leukoagglutinating antibody evokes cooperative leukotriene synthesis in pulmonary microvasculature. Model of transfusion-related acute lung injury.
Circulation research 1991;68(2):503-12.
1991: Grimminger F; Walmrath D; Walter H; Lutz F; Seeger W
Induction of vascular injury by Pseudomonas aeruginosa cytotoxin in rabbit lungs is associated with the generation of different leukotrienes and hydroxyeicosatetraenoic acids.
The Journal of infectious diseases 1991;163(2):362-70.
1991: Seeger W; Hübel J; Klapettek K; Pison U; Obertacke U; Joka T; Roka L
Procoagulant activity in bronchoalveolar lavage of severely traumatized patients--relation to the development of acute respiratory distress.
Thrombosis research 1991;61(1):53-64.
1991: Seeger W; Thede C; Günther A; Grube C
Surface properties and sensitivity to protein-inhibition of a recombinant apoprotein C-based phospholipid mixture in vitro--comparison to natural surfactant.
Biochimica et biophysica acta 1991;1081(1):45-52.
1991: Bertalanffy H; Gilsbach J M; Eggert H R; Seeger W
Microsurgery of deep-seated cavernous angiomas: report of 26 cases.
Acta neurochirurgica 1991;108(3-4):91-9.
1991: de Vries J; Gilsbach J; Seeger W
Technical improvements in the lateral suboccipital approach for neurovascular decompression of the trigeminal and facial nerves.
Acta neurochirurgica 1991;111(1-2):64-7.
1991: Seeger W; Grimminger F; Barden M; Becker G; Lohmeyer J; Heinrich D; Lasch H G
Omega-oxidized leukotriene B4 detected in the broncho-alveolar lavage fluid of patients with non-cardiogenic pulmonary edema, but not in those with cardiogenic edema.
Intensive care medicine 1991;17(1):1-6.
1990: Suttorp N; Flöer B; Schnittler H; Seeger W; Bhakdi S
Effects of Escherichia coli hemolysin on endothelial cell function.
Infection and immunity 1990;58(11):3796-801.
1990: Seeger W; Schneider U; Kreusler B; von Witzleben E; Walmrath D; Grimminger F; Neppert J
Reproduction of transfusion-related acute lung injury in an ex vivo lung model.
Blood 1990;76(7):1438-44.
1990: Grimminger F; Thomas M; Obernitz R; Walmrath D; Bhakdi S; Seeger W
Inflammatory lipid mediator generation elicited by viable hemolysin-forming Escherichia coli in lung vasculature.
The Journal of experimental medicine 1990;172(4):1115-25.
1990: Seeger W; Birkemeyer R G; Ermert L; Suttorp N; Bhakdi S; Duncker H R
Staphylococcal alpha-toxin-induced vascular leakage in isolated perfused rabbit lungs.
Laboratory investigation; a journal of technical methods and pathology 1990;63(3):341-9.
1990: Grimminger F; Walmrath D; Birkemeyer R G; Bhakdi S; Seeger W
Leukotriene and hydroxyeicosatetraenoic acid generation elicited by low doses of Escherichia coli hemolysin in rabbit lungs.
Infection and immunity 1990;58(8):2659-63.
1990: Grimminger F; Kreusler B; Schneider U; Becker G; Seeger W
Influence of microvascular adherence on neutrophil leukotriene generation. Evidence for cooperative eicosanoid synthesis.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(5):1866-72.
1990: Seeger W; Pison U; Buchhorn R; Obertacke U; Joka T
Surfactant abnormalities and adult respiratory failure.
Lung 1990;168 Suppl():891-902.
1989: Suttorp N; Fuchs T; Seeger W; Wilke A; Drenckhahn D
Role of Ca2+ and Mg2+ for endothelial permeability of water and albumin in vitro.
Laboratory investigation; a journal of technical methods and pathology 1989;61(2):183-91.
1989: Seeger W; Walter H; Suttorp N; Muhly M; Bhakdi S
Thromboxane-mediated hypertension and vascular leakage evoked by low doses of Escherichia coli hemolysin in rabbit lungs.
The Journal of clinical investigation 1989;84(1):220-7.
1989: Seeger W; Hartmann R; Neuhoff H; Bhakdi S
Local complement activation, thromboxane-mediated vasoconstriction, and vascular leakage in isolated lungs. Role of the terminal complement sequence.
The American review of respiratory disease 1989;139(1):88-99.
1989: Seeger W; Walter H; Neuhof H; Suttorp N; Bhakdi S
Escherichia coli hemolysin causes thromboxane-mediated hypertension and vascular leakage in rabbit lungs.
Progress in clinical and biological research 1989;308():67-72.
1989: Seeger W; Hartmann R; Neuhof H; Bhakdi S
In-situ complement activation, pulmonary hypertension and vascular leakage in rabbit lungs--the role of the terminal complement complex.
Progress in clinical and biological research 1989;308():283-9.
1989: Chiou S M; Eggert H R; Laborde G; Seeger W
Microsurgical unilateral approaches for spinal tumour surgery: eight years' experience in 256 primary operated patients.
Acta neurochirurgica 1989;100(3-4):127-33.
1989: Suttorp N; Seeger W; Neuhof H
Stimulation of arachidonate metabolism by endotoxin and the terminal complement complex C5b-8.
Progress in clinical and biological research 1989;301():217-21.
1989: Suttorp N; Seeger W; Neuhof H
Effects of bacterial exo- and endotoxins on endothelial arachidonate metabolism.
Progress in clinical and biological research 1989;308():119-25.
1989: Neuhof H; Hoffmann C; Seeger W; Suttorp N; Fritz H
Proteases as mediators of pulmonary vascular permeability.
Progress in clinical and biological research 1989;308():305-14.
1989: Suttorp N; Hessz T; Fuchs T; Seeger W; Drenckhahn D; Neuhof H
Effects of bacterial toxins and calcium-ionophores on endothelial permeability in vitro.
Progress in clinical and biological research 1989;308():127-31.
1988: Grimminger F; Menger M; Becker G; Seeger W
Potentiation of leukotriene production following sequestration of neutrophils in isolated lungs: indirect evidence for intercellular leukotriene A4 transfer.
Blood 1988;72(5):1687-92.
1988: Grimminger F; Becker G; Seeger W
High yield enzymatic conversion of intravascular leukotriene A4 in blood-free perfused lungs.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(7):2431-6.
1988: Suttorp N; Hessz T; Seeger W; Wilke A; Koob R; Lutz F; Drenckhahn D
Bacterial exotoxins and endothelial permeability for water and albumin in vitro.
The American journal of physiology 1988;255(3 Pt 1):C368-76.
1988: Seeger W; Moser U; Roka L
Effects of alpha-tocopherol, its carboxylic acid chromane compound and two novel antioxidant isoflavanones on prostaglandin H synthase activity and autodeactivation.
Naunyn-Schmiedeberg's archives of pharmacology 1988;338(1):74-81.
1988: Seeger W; Remy N E; Neuhof H
A highly sensitive gas chromatographic method does not detect exhalation of volatile hydrocarbons from isolated ventilated lungs under massive peroxidative stress.
Experimental lung research 1988;14(3):387-401.
1988: Seeger W; Neuhof H; Hall J; Roka L
Pulmonary vasoconstrictor response to soluble fibrin in isolated lungs: possible role of thromboxane generation.
Circulation research 1988;62(4):651-9.
1987: Seeger W; Menger M; Walmrath D; Becker G; Grimminger F; Neuhof H
Arachidonic acid lipoxygenase pathways and increased vascular permeability in isolated rabbit lungs.
The American review of respiratory disease 1987;136(4):964-72.
1987: Seeger W; Lasch H G
Septic lung.
Reviews of infectious diseases 1987;9 Suppl 5():S570-9.
1987: Seeger W; Ziegler A; Wolf H R
Serum alpha-tocopherol levels after high-dose enteral vitamin E administration in patients with acute respiratory failure.
Intensive care medicine 1987;13(6):395-400.
1986: Neuhof H; Seeger W; Wolf H R
Generation of mediators by limited proteolysis during blood coagulation and fibrinolysis--its pathogenetic role in the adult respiratory distress syndrome (ARDS).
Resuscitation 1986;14(1-2):23-32.
1985: Seeger W; Ernst C; Walmrath D; Neuhof H; Roka L
Influence of the thromboxane antagonist BM 13.177 on the arachidonic acid-induced increase in pulmonary vascular resistance and permeability in rabbit lungs.
Thrombosis research 1985;40(6):793-805.
1985: Seeger W; Lepper H; Wolf H R; Neuhof H
Alteration of alveolar surfactant function after exposure to oxidative stress and to oxygenated and native arachidonic acid in vitro.
Biochimica et biophysica acta 1985;835(1):58-67.
1985: Seeger W; Stöhr G; Wolf H R; Neuhof H
Alteration of surfactant function due to protein leakage: special interaction with fibrin monomer.
Journal of applied physiology (Bethesda, Md. : 1985) 1985;58(2):326-38.
1983: Seeger W; Wolf H R; Neuhof H
[Disorder of alveolar surface tension in relation to the development of edema in isolated rabbit lungs]
Praxis und Klinik der Pneumologie 1983;37 Suppl 1():753-6.
1983: Seeger W; Wolf H R; Neuhof H; Ròka L
[Arachidonic acid metabolites as mediators of an increase in resistance and a barrier disorder in pulmonary microcirculation]
Praxis und Klinik der Pneumologie 1983;37 Suppl 1():728-31.
1983: Eggert H R; Scheremet R; Seeger W; Gaitzsch J
Unilateral microsurgical approaches to extramedullary spinal tumours. Operative technique and results.
Acta neurochirurgica 1983;67(3-4):245-53.
1983: Seeger W; Wolf H R; Stähler G; Neuhof H
Alteration of pressure-volume characteristics due to different types of edema induction in isolated rabbit lungs.
Respiration; international review of thoracic diseases 1983;44(4):273-81.
1983: Seeger W; Neuhof H; Graubert E; Wolf H; Roka L
Comparative influence of the Ca-ionophore A 23187, bradykinin, kallidin and eledoisin on the rabbit pulmonary vasculature with special reference to arachidonate metabolism.
Advances in experimental medicine and biology 1983;156():533-51.
1983: Seeger W; Wolf H R; Neuhof H; Roka L
Release and oxygenation of arachidonic acid: nonspecific triggering and pathophysiological consequences in isolated rabbit lungs.
Advances in prostaglandin, thromboxane, and leukotriene research 1983;12():99-105.
1983: Seeger W; Wolf H; Graubert E; Moser U; Neuhof H; Roka L
Influence of aprotinin and gabexate mesilate on arachidonic acid release by the Ca-ionophore A 23187 in the lung.
Advances in experimental medicine and biology 1983;156():553-67.
1982: Neuhof H; Seeger W; Wolf H; Róka L; Lasch H G
[Consumptive coagulopathy and lung function]
Der Internist 1982;23(8):457-62.
1982: Seeger W; Wolf H; Stähler G; Neuhof H; Róka L
Influence of tocopherol, its chromane compound, phytyl chains and superoxide dismutase on increased vascular resistance and permeability due to arachidonate metabolism in isolated rabbit lung.
Prostaglandins 1982;23(2):175-84.
1982: Seeger W; Wolf H; Stähler G; Neuhof H; Róka L
Increased pulmonary vascular resistance and permeability due to arachidonate metabolism in isolated rabbit lungs.
Prostaglandins 1982;23(2):157-73.
1981: Seeger W; Wolf H; Stähler G; Neuhof H; Róka L
[Increase of pulmonary vascular resistance and permeability due to the metabolism of free arachidonic acid (author's transl)]
Klinische Wochenschrift 1981;59(9):459-61.
1981: Wolf H; Seeger W; Stähler G; Neuhof H; Róka L
[The antioxidative chromane structure of alpha-tocopherol protects against the consequences of arachidonic acid release in the pulmonary vascular bed (author's transl)]
Klinische Wochenschrift 1981;59(9):463-5.

Sign-in to see more

Sign-in free and Explore the Exciting World of BiomedExperts:

NetworkView

Werner Seeger

Research Profile (preview)

Anatomy

Living Beings

Disorders

Physiology

Chemicals & Drugs

Procedures

Network (preview)

Publications

Sign in free and see...

Visualized networks:

GeoTargeted Searches:

Research Profiles:

Geonetwork of Werner Seeger (preview)

All Publications