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Shakuntla Seetharam

Research Profile

Chemicals & Drugs

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Electrophoresis, Polyacrylamide Gel

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Amino Acid Sequences

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Publications

TOP 3
Rajiv Ahuja; Raghunatha Yammani; Joseph Bauer; Seema Kalra; Shakuntla Seetharam; Bellur Seetharam
Interactions of cubilin with megalin and the product of the amnionless gene (AMN): effect on its stability.
Seema Kalra; Rajiv Ahuja; Elena Mutti; Daniela Veber; Shakuntla Seetharam; Giuseppe Scalabrino; Bellur Seetharam
Cobalamin-mediated regulation of transcobalamin receptor levels in rat organs.
Seema Kalra; Ning Li; Raghunatha R Yammani; Shakuntla Seetharam; Bellur Seetharam
Cobalamin (vitamin B12) binding, phylogeny, and synteny of human transcobalamin.

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All Publications

2008: Rajiv Ahuja; Raghunatha Yammani; Joseph Bauer; Seema Kalra; Shakuntla Seetharam; Bellur Seetharam
Interactions of cubilin with megalin and the product of the amnionless gene (AMN): effect on its stability.
The Biochemical journal 2008;410(2):301-8.
2007: Seema Kalra; Rajiv Ahuja; Elena Mutti; Daniela Veber; Shakuntla Seetharam; Giuseppe Scalabrino; Bellur Seetharam
Cobalamin-mediated regulation of transcobalamin receptor levels in rat organs.
Archives of biochemistry and biophysics 2007;463(1):128-32.
2004: Seema Kalra; Ning Li; Raghunatha R Yammani; Shakuntla Seetharam; Bellur Seetharam
Cobalamin (vitamin B12) binding, phylogeny, and synteny of human transcobalamin.
Archives of biochemistry and biophysics 2004;431(2):189-96.
2004: Seema Kalra; Shakuntla Seetharam; Raghunatha R Yammani; Bellur Seetharam
Rat transcobalamin: cloning and regulation of mRNA expression.
The Journal of physiology 2004;556(Pt 2):623-35.
2003: Seema Kalra; Ning Li; Shakuntla Seetharam; David H Alpers; Bellur Seetharam
Function and stability of human transcobalamin II: role of intramolecular disulfide bonds C98-C291 and C147-C187.
American journal of physiology. Cell physiology 2003;285(1):C150-60.
2003: Raghunatha R Yammani; Shakuntla Seetharam; Nancy M Dahms; Bellur Seetharam
Transcobalamin II receptor interacts with megalin in the renal apical brush border membrane.
The Journal of membrane biology 2003;193(1):57-66.
2003: Sravan K Vanamala; Shakuntla Seetharam; Raghunatha R Yammani; Bellur Seetharam
Human transcobalamin II receptor binds to Staphylococcus aureus protein A: implications as to its structure and function.
Archives of biochemistry and biophysics 2003;411(2):204-14.
2002: Raghunatha R Yammani; Mukut Sharma; Shakuntla Seetharam; John E Moulder; Nancy M Dahms; Bellur Seetharam
Loss of albumin and megalin binding to renal cubilin in rats results in albuminuria after total body irradiation.
American journal of physiology. Regulatory, integrative and comparative physiology 2002;283(2):R339-46.
2001: Raghunatha R Yammani; Shakuntla Seetharam; Bellur Seetharam
Identification and characterization of two distinct ligand binding regions of cubilin.
The Journal of biological chemistry 2001;276(48):44777-84.
2001: Raghunatha R Yammani; Shakuntla Seetharam; Bellur Seetharam
Cubilin and megalin expression and their interaction in the rat intestine: effect of thyroidectomy.
American journal of physiology. Endocrinology and metabolism 2001;281(5):E900-7.
1998: Santanu Bose; Steven J Chapin; Shakuntla Seetharam; Jimmy B Feix; Keith E Mostov; Bellur Seetharam
Brefeldin A (BFA) inhibits basolateral membrane (BLM) delivery and dimerization of transcobalamin II receptor in human intestinal epithelial Caco-2 cells. BFA effects on BLM cholesterol content.
The Journal of biological chemistry 1998;273(26):16163-9.
1998: Ning Li; Shakuntla Seetharam; Bellur Seetharam
Characterization of the human transcobalamin II promoter. A proximal GC/GT box is a dominant negative element.
The Journal of biological chemistry 1998;273(26):16104-11.
1997: Santanu Bose; Shakuntla Seetharam; Nancy M Dahms; Bellur Seetharam
Bipolar functional expression of transcobalamin II receptor in human intestinal epithelial Caco-2 cells.
The Journal of biological chemistry 1997;272(6):3538-43.
1996: Santanu Bose; Jimmy B Feix; Shakuntla Seetharam; Bellur Seetharam
Dimerization of transcobalamin II receptor. Requirement of a structurally ordered lipid bilayer.
The Journal of biological chemistry 1996;271(20):11718-25.
1996: Santanu Bose; R Komorowski; Shakuntla Seetharam; B Gilfix; D S Rosenblatt; Bellur Seetharam
In vitro and in vivo inactivation of transcobalamin II receptor by its antiserum.
The Journal of biological chemistry 1996;271(8):4195-200.
1995: Santanu Bose; Shakuntla Seetharam; Timothy G Hammond; Bellur Seetharam
Regulation of expression of transcobalamin II receptor in the rat.
The Biochemical journal 1995;310 ( Pt 3)():923-9.
1995: Santanu Bose; Shakuntla Seetharam; Bellur Seetharam
Membrane expression and interactions of human transcobalamin II receptor.
The Journal of biological chemistry 1995;270(14):8152-7.
1995: Ning Li; Shakuntla Seetharam; Bellur Seetharam
Genomic structure of human transcobalamin II: comparison to human intrinsic factor and transcobalamin I.
Biochemical and biophysical research communications 1995;208(2):756-64.
1994: Kalathur S Ramanujam; Shakuntla Seetharam; Nancy M Dahms; Bellur Seetharam
Effect of processing inhibitors on cobalamin (vitamin B12) transcytosis in polarized opossum kidney cells.
Archives of biochemistry and biophysics 1994;315(1):8-15.
1994: Ning Li; G K Sood; Shakuntla Seetharam; Bellur Seetharam
Polymorphism of human transcobalamin II: substitution of proline and/or glutamine residues by arginine.
Biochimica et biophysica acta 1994;1219(2):515-20.
1994: Ning Li; D S Rosenblatt; Barton A. Kamen; Shakuntla Seetharam; Bellur Seetharam
Identification of two mutant alleles of transcobalamin II in an affected family.
Human molecular genetics 1994;3(10):1835-40.
1994: Ning Li; Shakuntla Seetharam; D S Rosenblatt; Bellur Seetharam
Expression of transcobalamin II mRNA in human tissues and cultured fibroblasts from normal and transcobalamin II-deficient patients.
The Biochemical journal 1994;301 ( Pt 2)():585-90.
1993: Kalathur S Ramanujam; Shakuntla Seetharam; Bellur Seetharam
Intrinsic factor-cobalamin receptor activity in a marsupial, the American opossum (Didelphis virginiana).
Comparative biochemistry and physiology. Comparative physiology 1993;104(4):771-5.
1993: Kalathur S Ramanujam; Shakuntla Seetharam; Bellur Seetharam
Regulated expression of intrinsic factor-cobalamin receptor by rat visceral yolk sac and placental membranes.
Biochimica et biophysica acta 1993;1146(2):243-6.
1993: Ning Li; Shakuntla Seetharam; Jan Lindemans; D H Alpers; F Arwert; Bellur Seetharam
Isolation and sequence analysis of variant forms of human transcobalamin II.
Biochimica et biophysica acta 1993;1172(1-2):21-30.
1992: Shakuntla Seetharam; Kalathur S Ramanujam; Bellur Seetharam
Synthesis and brush border expression of intrinsic factor-cobalamin receptor from rat renal cortex.
The Journal of biological chemistry 1992;267(11):7421-7.
1992: Shakuntla Seetharam; Kalathur S Ramanujam; Bellur Seetharam
Intrinsic factor receptor activity and cobalamin transport in bile duct-ligated rats.
The American journal of physiology 1992;262(2 Pt 1):G210-5.
1992: Kalathur S Ramanujam; Shakuntla Seetharam; Bellur Seetharam
Leupeptin and ammonium chloride inhibit intrinsic factor mediated transcytosis of [57Co]cobalamin across polarized renal epithelial cells.
Biochemical and biophysical research communications 1992;182(2):439-46.
1991: Shakuntla Seetharam; Nancy M Dahms; Ning Li; Bellur Seetharam
Functional expression of transcobalamin II cDNA in Xenopus laevis oocytes.
Biochemical and biophysical research communications 1991;181(3):1151-5.
1991: Bellur Seetharam; Kalathur S Ramanujam; Shakuntla Seetharam; Ning Li; J C Fyfe
Normal and abnormal physiology of intrinsic factor mediated absorption of cobalamin (vitamin B12).
Indian journal of biochemistry & biophysics 1991;28(5-6):324-30.
1991: Kalathur S Ramanujam; Shakuntla Seetharam; Bellur Seetharam
Synthesis and secretion of cobalamin binding proteins by opossum kidney cells.
Biochemical and biophysical research communications 1991;179(1):543-50.
1991: Kalathur S Ramanujam; Shakuntla Seetharam; Nancy M Dahms; Bellur Seetharam
Functional expression of intrinsic factor-cobalamin receptor by renal proximal tubular epithelial cells.
The Journal of biological chemistry 1991;266(20):13135-40.
1991: Shakuntla Seetharam; Nancy M Dahms; Ning Li; Kalathur S Ramanujam; Bellur Seetharam
In vitro translation and expression of renal intrinsic factor-cobalamin receptor.
Biochemical and biophysical research communications 1991;177(2):751-6.
1991: Kalathur S Ramanujam; Shakuntla Seetharam; M Ramasamy; Bellur Seetharam
Expression of cobalamin transport proteins and cobalamin transcytosis by colon adenocarcinoma cells.
The American journal of physiology 1991;260(3 Pt 1):G416-22.
1990: Kalathur S Ramanujam; Shakuntla Seetharam; M Ramasamy; Bellur Seetharam
Renal brush border membrane bound intrinsic factor.
Biochimica et biophysica acta 1990;1030(1):157-64.