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Siegfried Segaert

Research Profile

Chemicals & Drugs

Anatomy

Disorders

Phenomena

Ultraviolet Rays

Physiology

Cell Differentiation

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Publications

TOP 3
Enno Christophers; Gary Milligan; Charles T Molta; Siegfried Segaert; Robert Boggs
Clinical improvement and satisfaction with biologic therapy in patients with severe plaque psoriasis: results of a European cross-sectional observational study.
Patrice Cacoub; Nicolas Dupin; Geoffrey Dusheiko; Christophe Hézode; Jann Lübbe; Odile Picard; Ramon Pujol; Marc Bourlière; Peter Buggisch; Siegfried Segaert; Bing Thio; Jean-Claude Roujeau
Dermatological side effects of hepatitis C and its treatment: patient management in the era of direct-acting antivirals.
Jean-François Rahier; Michel Moutschen; Alfons Van Gompel; Marc Van Ranst; Edouard Louis; Siegfried Segaert; Pierre Masson; Filip De Keyser
Vaccinations in patients with immune-mediated inflammatory diseases.

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All Publications

2013: Enno Christophers; Gary Milligan; Charles T Molta; Siegfried Segaert; Robert Boggs
Clinical improvement and satisfaction with biologic therapy in patients with severe plaque psoriasis: results of a European cross-sectional observational study.
The Journal of dermatological treatment 2013;24(3):193-8.
2012: Patrice Cacoub; Nicolas Dupin; Geoffrey Dusheiko; Christophe Hézode; Jann Lübbe; Odile Picard; Ramon Pujol; Marc Bourlière; Peter Buggisch; Siegfried Segaert; Bing Thio; Jean-Claude Roujeau
Dermatological side effects of hepatitis C and its treatment: patient management in the era of direct-acting antivirals.
Journal of hepatology 2012;56(2):455-63.
2010: Jean-François Rahier; Michel Moutschen; Alfons Van Gompel; Marc Van Ranst; Edouard Louis; Siegfried Segaert; Pierre Masson; Filip De Keyser
Vaccinations in patients with immune-mediated inflammatory diseases.
Rheumatology (Oxford, England) 2010;49(10):1815-27.
2010: Mario Lacouture; Michael L Maitland; Siegfried Segaert; Ann Setser; Robert Baran; Lindy P Fox; Joel B Epstein; Andrei Barasch; Lawrence Einhorn; Lynne Wagner; Dennis P West; Bernardo L Rapoport; Mark G Kris; Ethan Basch; Beth Eaby; Sandra Kurtin; Elise A Olsen; Alice Chen; Janet E Dancey; Andy Trotti
A proposed EGFR inhibitor dermatologic adverse event-specific grading scale from the MASCC skin toxicity study group.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 2010;18(4):509-22.
2009: Siegfried Segaert; Gabriela Chiritescu; Liesbeth Lemmens; Kristien Dumon; Eric Van Cutsem; Sabine Tejpar
Skin toxicities of targeted therapies.
European journal of cancer (Oxford, England : 1990) 2009;45 Suppl 1():295-308.
2009: H Fidder; F Schnitzler; Marc Ferrante; Maja Noman; K Katsanos; Siegfried Segaert; Liesbet Henckaerts; Gert van Assche; Severine Vermeire; Paul Rutgeerts
Long-term safety of infliximab for the treatment of inflammatory bowel disease: a single-centre cohort study.
Gut 2009;58(4):501-8.
2009: Siegfried Segaert
Etanercept, improved dosage schedules and combinations in the treatment of psoriasis: an update.
Journal of inflammation research 2009;2():29-36.
2009: Kristian Reich; Siegfried Segaert; Peter Van de Kerkhof; Cis Durian; Marie Pierre Boussuge; Laurence Paolozzi; Joseph Wajdula; Robert Boggs
Once-weekly administration of etanercept 50 mg improves patient-reported outcomes in patients with moderate-to-severe plaque psoriasis.
Dermatology (Basel, Switzerland) 2009;219(3):239-49.
2009: P C M van de Kerkhof; V Hoffmann; Alexander Anstey; L Barnes; C Bolduc; K Reich; S Saari; Siegfried Segaert; L Vaillant
A new scalp formulation of calcipotriol plus betamethasone dipropionate compared with each of its active ingredients in the same vehicle for the treatment of scalp psoriasis: a randomized, double-blind, controlled trial.
The British journal of dermatology 2009;160(1):170-6.
2008: Siegfried Segaert
Vitamin D regulation of cathelicidin in the skin: toward a renaissance of vitamin D in dermatology?
The Journal of investigative dermatology 2008;128(4):773-5.
2008: Siegfried Segaert; Thierry Simonart
The epidermal vitamin D system and innate immunity: some more light shed on this unique photoendocrine system?
Dermatology (Basel, Switzerland) 2008;217(1):7-11.
2007: Siegfried Segaert; Eric Van Cutsem
Clinical management of EGFRI dermatologic toxicities: the European perspective.
Oncology (Williston Park, N.Y.) 2007;21(11 Suppl 5):22-6.
2006: Katleen Vantieghem; Petra De Haes; Roger Bouillon; Siegfried Segaert
Dermal fibroblasts pretreated with a sterol Delta7-reductase inhibitor produce 25-hydroxyvitamin D3 upon UVB irradiation.
Journal of photochemistry and photobiology. B, Biology 2006;85(1):72-8.
2006: Katleen Vantieghem; Lut Overbergh; Geert Carmeliet; Petra De Haes; Roger Bouillon; Siegfried Segaert
UVB-induced 1,25(OH)2D3 production and vitamin D activity in intestinal CaCo-2 cells and in THP-1 macrophages pretreated with a sterol Delta7-reductase inhibitor.
Journal of cellular biochemistry 2006;99(1):229-40.
2006: Katleen Vantieghem; Anne-Marie Kissmeyer; Petra De Haes; Roger Bouillon; Siegfried Segaert
UVB-induced production of 1,25-dihydroxyvitamin D3 and vitamin D activity in human keratinocytes pretreated with a sterol delta7-reductase inhibitor.
Journal of cellular biochemistry 2006;98(1):81-92.
2006: Siegfried Segaert; Laëtitia Bouérat Duvold
Calcipotriol cream: a review of its use in the management of psoriasis.
The Journal of dermatological treatment 2006;17(6):327-37.
2005: Siegfried Segaert; Eric Van Cutsem
Clinical signs, pathophysiology and management of skin toxicity during therapy with epidermal growth factor receptor inhibitors.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2005;16(9):1425-33.
2005: Siegfried Segaert; Josep Tabernero; Olivier Chosidow; Thomas Dirschka; Joern Elsner; Luca Mancini; Tim Maughan; Jean-Fran Ois Morere; Armando Santoro; Alberto Sobrero; Eric Van Cutsem; Alison Layton
The management of skin reactions in cancer patients receiving epidermal growth factor receptor targeted therapies.
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2005;3(8):599-606.
2005: Petra De Haes; Marjan Garmyn; Annemieke Verstuyf; Pierre J De Clercq; Maurits Vandewalle; Hugo Degreef; Katleen Vantieghem; Roger Bouillon; Siegfried Segaert
1,25-Dihydroxyvitamin D3 and analogues protect primary human keratinocytes against UVB-induced DNA damage.
Journal of photochemistry and photobiology. B, Biology 2005;78(2):141-8.
2004: Petra De Haes; Marjan Garmyn; Geert Carmeliet; Hugo Degreef; Katleen Vantieghem; Roger Bouillon; Siegfried Segaert
Molecular pathways involved in the anti-apoptotic effect of 1,25-dihydroxyvitamin D3 in primary human keratinocytes.
Journal of cellular biochemistry 2004;93(5):951-67.
2004: Ludwig Missiaen; Luc Raeymaekers; Leonard Dode; Jo Vanoevelen; Kurt Van Baelen; Jan B Parys; Geert Callewaert; Humbert De Smedt; Siegfried Segaert; Frank Wuytack
SPCA1 pumps and Hailey-Hailey disease.
Biochemical and biophysical research communications 2004;322(4):1204-13.
2004: Petra De Haes; Marjan Garmyn; Annemieke Verstuyf; Pierre J De Clercq; Maurits Vandewalle; Katleen Vantieghem; Hugo Degreef; Roger Bouillon; Siegfried Segaert
Two 14-epi analogues of 1,25-dihydroxyvitamin D3 protect human keratinocytes against the effects of UVB.
Archives of dermatological research 2004;295(12):527-34.
2004: Pieter Evenepoel; Miranda Zeegers; Siegfried Segaert; Kathleen Claes; Dirk Kuypers; Bart Maes; Patrick Flamen; Sabine Fransis; Yves Vanrenterghem
Nephrogenic fibrosing dermopathy: a novel, disabling disorder in patients with renal failure.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2004;19(2):469-73.
2003: Petra De Haes; Marjan Garmyn; Hugo Degreef; Katleen Vantieghem; Roger Bouillon; Siegfried Segaert
1,25-Dihydroxyvitamin D3 inhibits ultraviolet B-induced apoptosis, Jun kinase activation, and interleukin-6 production in primary human keratinocytes.
Journal of cellular biochemistry 2003;89(4):663-73.
2000: Siegfried Segaert; Hugo Degreef; Roger Bouillon
Vitamin D receptor expression is linked to cell cycle control in normal human keratinocytes.
Biochemical and biophysical research communications 2000;279(1):89-94.
2000: Annemieke Verstuyf; Siegfried Segaert; Lieve Verlinden; Roger Bouillon; C Mathieu
Recent developments in the use of vitamin D analogues.
Expert opinion on investigational drugs 2000;9(3):443-55.
2000: Siegfried Segaert; Marjan Garmyn; Hugo Degreef; Roger Bouillon
Suppression of vitamin D receptor and induction of retinoid X receptor alpha expression during squamous differentiation of cultured keratinocytes.
The Journal of investigative dermatology 2000;114(3):494-501.
2000: Siegfried Segaert; SJ Courtois; Marjan Garmyn; Hugo Degreef; Roger Bouillon
The flavonoid apigenin suppresses vitamin D receptor expression and vitamin D responsiveness in normal human keratinocytes.
Biochemical and biophysical research communications 2000;268(1):237-41.
1999: Annemieke Verstuyf; Lieve Verlinden; Siegfried Segaert; Evelyne van Etten; C Mathieu; R Bouillon
Nonclassical effects of 1alpha,25-dihydroxyvitamin D(3) and its analogs.
Mineral and electrolyte metabolism 1999;25(4-6):345-8.
1998: Siegfried Segaert; Marjan Garmyn; Hugo Degreef; Roger Bouillon
Anchorage-dependent expression of the vitamin D receptor in normal human keratinocytes.
The Journal of investigative dermatology 1998;111(4):551-8.
1998: Siegfried Segaert; R Bouillon
Vitamin D and regulation of gene expression.
Current opinion in clinical nutrition and metabolic care 1998;1(4):347-54.
1998: Annemieke Verstuyf; Siegfried Segaert; Lieve Verlinden; Kristina Casteels; Roger Bouillon; Chantal Mathieu
Recent developments in the use of vitamin D analogues.
Current opinion in nephrology and hypertension 1998;7(4):397-403.
1998: SJ Courtois; Siegfried Segaert; Hugo Degreef; Roger Bouillon; Marjan Garmyn
Ultraviolet B suppresses vitamin D receptor gene expression in keratinocytes.
Biochemical and biophysical research communications 1998;246(1):64-9.
1998: Roger Bouillon; Geert Carmeliet; Evis Daci; Siegfried Segaert; Annemieke Verstuyf
Vitamin D metabolism and action.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 1998;8 Suppl 2():S13-9.
1997: Siegfried Segaert; Marjan Garmyn; Hugo Degreef; Roger Bouillon
Retinoic acid modulates the anti-proliferative effect of 1,25-dihydroxyvitamin D3 in cultured human epidermal keratinocytes.
The Journal of investigative dermatology 1997;109(1):46-54.
1995: Roger Bouillon; Marjan Garmyn; Annemieke Verstuyf; Siegfried Segaert; Kristina Casteels; Chantal Mathieu
Paracrine role for calcitriol in the immune system and skin creates new therapeutic possibilities for vitamin D analogs.
European journal of endocrinology / European Federation of Endocrine Societies 1995;133(1):7-16.