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Rony Seger

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Ludmila Sviridonov; Zhong Yao; Tali Hana Bar-Lev; Masha Dobkin-Bekman; Linor Formishell; Marcelo G Kazanietz; Shani Kravchook; Fiorenza Przedecki; Liat Rahamim-Ben Navi; Rony Seger; Boris Shterntal; Zvi Naor
Differential signaling of the GnRH receptor in pituitary gonadotrope cell lines and prostate cancer cell lines.
Ido Ben-Ami; Zvi Naor; Zhong Yao; Rony Seger
Gq protein-induced apoptosis is mediated by AKT kinase inhibition that leads to protein kinase C-induced c-Jun N-terminal kinase activation.
Alexander Plotnikov; Dana Chuderland; Yael Karamansha; Oded Livnah; Rony Seger
Nuclear extracellular signal-regulated kinase 1 and 2 translocation is mediated by casein kinase 2 and accelerated by autophosphorylation.

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All Publications

2013: Ludmila Sviridonov; Zhong Yao; Tali Hana Bar-Lev; Masha Dobkin-Bekman; Linor Formishell; Marcelo G Kazanietz; Shani Kravchook; Fiorenza Przedecki; Liat Rahamim-Ben Navi; Rony Seger; Boris Shterntal; Zvi Naor
Differential signaling of the GnRH receptor in pituitary gonadotrope cell lines and prostate cancer cell lines.
Molecular and cellular endocrinology 2013;369(1-2):107-18.
2011: Ido Ben-Ami; Zvi Naor; Zhong Yao; Rony Seger
Gq protein-induced apoptosis is mediated by AKT kinase inhibition that leads to protein kinase C-induced c-Jun N-terminal kinase activation.
The Journal of biological chemistry 2011;286(35):31022-31.
2011: Alexander Plotnikov; Dana Chuderland; Yael Karamansha; Oded Livnah; Rony Seger
Nuclear extracellular signal-regulated kinase 1 and 2 translocation is mediated by casein kinase 2 and accelerated by autophosphorylation.
Molecular and cellular biology 2011;31(17):3515-30.
2011: Abraham Amsterdam; Alon Ben-Arie; Diana Prus; Calanit Raanan; Letizia Schreiber; Elias Shezen; Yasmin Slilat; Rony Seger
Nuclear localization of phosphorylated ERK1 and ERK2 as markers for the progression of ovarian cancer.
International journal of oncology 2011;39(3):649-56.
2011: Elke Burgermeister; Henrik Einwächter; Teresa Friedrich; Ivana Hitkova; Aurel Perren; Ivonne Regel; Christoph Röcken; Roland M Schmid; Rony Seger; Matthew B Wright; Wolfgang Zimmermann; Matthias P A Ebert
The Ras inhibitors caveolin-1 and docking protein 1 activate peroxisome proliferator-activated receptor γ through spatial relocalization at helix 7 of its ligand-binding domain.
Molecular and cellular biology 2011;31(16):3497-510.
2011: Amir Schajnovitz; Tomer Itkin; Gabriele D'Uva; Alexander Kalinkovich; Karin Golan; Aya Ludin; Dror Cohen; Ziv Shulman; Abraham Avigdor; Arnon Nagler; Orit Kollet; Rony Seger; Tsvee Lapidot
CXCL12 secretion by bone marrow stromal cells is dependent on cell contact and mediated by connexin-43 and connexin-45 gap junctions.
Nature immunology 2011;12(5):391-8.
2011: Inbal Wortzel; Rony Seger
The ERK Cascade: Distinct Functions within Various Subcellular Organelles.
Genes & cancer 2011;2(3):195-209.
2011: Alexander Konson; Sunila Pradeep; Cosimo Walter D'Acunto; Rony Seger
Pigment epithelium-derived factor and its phosphomimetic mutant induce JNK-dependent apoptosis and p38-mediated migration arrest.
The Journal of biological chemistry 2011;286(5):3540-51.
2010: Masha Dobkin-Bekman; Liat Rahamin-Ben Navi; Liat Rahamim Ben-Navi; Boris Shterntal; Ludmila Sviridonov; Fiorenza Przedecki; Michal Naidich-Exler; Chaya Brodie; Rony Seger; Zvi Naor
Differential role of PKC isoforms in GnRH and phorbol 12-myristate 13-acetate activation of extracellular signal-regulated kinase and Jun N-terminal kinase.
Endocrinology 2010;151(10):4894-907.
2010: Libbat Tirosh-Finkel; Amit Zeisel; Miriam Brodt-Ivenshitz; Ayelet Shamai; Zhong Yao; Rony Seger; Eytan Domany; Eldad Tzahor
BMP-mediated inhibition of FGF signaling promotes cardiomyocyte differentiation of anterior heart field progenitors.
Development (Cambridge, England) 2010;137(18):2989-3000.
2010: Shlomit Reich-Zeliger; Yaki Eidelstein; David Hagin; Yaron E Antebi; Rony Seger; Yair Reisner
Deletion of alloreactive T cells by veto cytotoxic T lymphocytes is mediated through extracellular signal-regulated kinase phosphorylation.
Transplantation 2010;90(4):380-6.
2010: Oran Erster; Rony Seger; Mordechai Liscovitch
Ligand interaction scan (LIScan) in the study of ERK8.
Biochemical and biophysical research communications 2010;399(1):37-41.
2010: Alexander Konson; Sunila Pradeep; Rony Seger
Phosphomimetic mutants of pigment epithelium-derived factor with enhanced antiangiogenic activity as potent anticancer agents.
Cancer research 2010;70(15):6247-57.
2010: Eldar Zehorai; Zhong Yao; Alexander Plotnikov; Rony Seger
The subcellular localization of MEK and ERK--a novel nuclear translocation signal (NTS) paves a way to the nucleus.
Molecular and cellular endocrinology 2010;314(2):213-20.
2010: Zhong Yao; Seunghee Yoon; Eyal Kalie; Ziv Raviv; Rony Seger
Calcium regulation of EGF-induced ERK5 activation: role of Lad1-MEKK2 interaction.
PloS one 2010;5(9):e12627.
2010: Shiri Procaccia; Sarah Kraus; Rony Seger
Determination of ERK activity: anti-phospho-ERK antibodies and in vitro phosphorylation.
Methods in molecular biology (Clifton, N.J.) 2010;661():39-58.
2010: Yonat Keshet; Rony Seger
The MAP kinase signaling cascades: a system of hundreds of components regulates a diverse array of physiological functions.
Methods in molecular biology (Clifton, N.J.) 2010;661():3-38.
2009: Masha Dobkin-Bekman; Michal Naidich; Liat Rahamim; Fiorenza Przedecki; Tal Almog; Stefan Lim; Philippa Melamed; Ping Liu; Thorsten Wohland; Zhong Yao; Rony Seger; Zvi Naor
A preformed signaling complex mediates GnRH-activated ERK phosphorylation of paxillin and FAK at focal adhesions in L beta T2 gonadotrope cells.
Molecular endocrinology (Baltimore, Md.) 2009;23(11):1850-64.
2009: Zhong Yao; Rony Seger
The ERK signaling cascade--views from different subcellular compartments.
BioFactors (Oxford, England) 2009;35(5):407-16.
2009: Yoav D Shaul; Gilad Gibor; Alexander Plotnikov; Rony Seger
Specific phosphorylation and activation of ERK1c by MEK1b: a unique route in the ERK cascade.
Genes & development 2009;23(15):1779-90.
2008: Dana Chuderland; Alexander Konson; Rony Seger
Identification and characterization of a general nuclear translocation signal in signaling proteins.
Molecular cell 2008;31(6):850-61.
2008: Vered Lev-Goldman; Brenda Mester; Nurit Ben-Aroya; Tamar Hanoch; Barbara Rupp; Tsvetanka Stanoeva; Georg Gescheidt; Rony Seger; Yitzhak Koch; Lev Weiner; Mati Fridkin
Conjugates of gonadotropin releasing hormone (GnRH) with carminic acid: Synthesis, generation of reactive oxygen species (ROS) and biological evaluation.
Bioorganic & medicinal chemistry 2008;16(14):6789-98.
2008: Tal Almog; Shlomi Lazar; N Reiss; Nir Etkovitz; Eyal Milch; Nir Rahamim; Masha Dobkin-Bekman; Ronit Rotem; Moshe Kalina; Jacob Ramon; Arieh Raziel; Haim Breitbart; Haim Brietbart; Rony Seger; Zvi Naor
Identification of extracellular signal-regulated kinase 1/2 and p38 MAPK as regulators of human sperm motility and acrosome reaction and as predictors of poor spermatozoan quality.
The Journal of biological chemistry 2008;283(21):14479-89.
2008: Dana Chuderland; Goldie Marmor; Alla Shainskaya; Rony Seger
Calcium-mediated interactions regulate the subcellular localization of extracellular signal-regulated kinases.
The Journal of biological chemistry 2008;283(17):11176-88.
2008: Dana Chuderland; Rony Seger
Calcium regulates ERK signaling by modulating its protein-protein interactions.
Communicative & integrative biology 2008;1(1):4-5.
2007: Sarit Bendetz-Nezer; Rony Seger
Role of non-phosphorylated activation loop residues in determining ERK2 dephosphorylation, activity, and subcellular localization.
The Journal of biological chemistry 2007;282(34):25114-22.
2007: Joseph Friedman; Sarah Kraus; Yirmi Hauptman; Yoni Schiff; Rony Seger
Mechanism of short-term ERK activation by electromagnetic fields at mobile phone frequencies.
The Biochemical journal 2007;405(3):559-68.
2007: Yosef Shaul; Rony Seger
The MEK/ERK cascade: from signaling specificity to diverse functions.
Biochimica et biophysica acta 2007;1773(8):1213-26.
2007: Elke Burgermeister; Rony Seger
MAPK kinases as nucleo-cytoplasmic shuttles for PPARgamma.
Cell cycle (Georgetown, Tex.) 2007;6(13):1539-48.
2007: Neil L Spector; Yosef Yarden; Bradley Smith; Ljuba Lyass; Patricia Trusk; Karen Pry; Jason E Hill; Wenle Xia; Rony Seger; Sarah S Bacus
Activation of AMP-activated protein kinase by human EGF receptor 2/EGF receptor tyrosine kinase inhibitor protects cardiac cells.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(25):10607-12.
2007: Elke Burgermeister; Dana Chuderland; Tamar Hanoch; Markus Meyer; Mordechai Liscovitch; Rony Seger
Interaction with MEK causes nuclear export and downregulation of peroxisome proliferator-activated receptor gamma.
Molecular and cellular biology 2007;27(3):803-17.
2007: Malka Cohen-Armon; Leonid Visochek; Dana Rozensal; Adi Kalal; Ilona Geistrikh; Rodika Klein; Sarit Bendetz-Nezer; Zhong Yao; Rony Seger
DNA-independent PARP-1 activation by phosphorylated ERK2 increases Elk1 activity: a link to histone acetylation.
Molecular cell 2007;25(2):297-308.
2006: Eran Perlson; Izhak M. Michaelevski; Noga Kowalsman; Keren Ben-Yaakov; Maya Shaked; Rony Seger; Miriam Eisenstein; Mike Fainzilber
Vimentin binding to phosphorylated Erk sterically hinders enzymatic dephosphorylation of the kinase.
Journal of molecular biology 2006;364(5):938-44.
2006: Hava Ben David; Badiga Venkata Aruna; Rony Seger; Michael Sela; Edna Mozes
A 50-kDa ERK-like protein is up-regulated by a dual altered peptide ligand that suppresses myasthenia gravis-associated responses.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(48):18232-7.
2006: Ido Ben-Ami; Sarit Freimann; Leah Armon; Ada Dantes; Deborah Strassburger; S Friedler; A Raziel; Rony Seger; Raphael Ron-El; Abraham Amsterdam
PGE2 up-regulates EGF-like growth factor biosynthesis in human granulosa cells: new insights into the coordination between PGE2 and LH in ovulation.
Molecular human reproduction 2006;12(10):593-9.
2006: Masha Dobkin-Bekman; Michal Naidich; Adam J Pawson; Robert P Millar; Rony Seger; Zvi Naor
Activation of mitogen-activated protein kinase (MAPK) by GnRH is cell-context dependent.
Molecular and cellular endocrinology 2006;252(1-2):184-90.
2006: Galia Maik-Rachline; Rony Seger
Variable phosphorylation states of pigment-epithelium-derived factor differentially regulate its function.
Blood 2006;107(7):2745-52.
2006: Sarah Kraus; Zvi Naor; Rony Seger
Gonadotropin-releasing hormone in apoptosis of prostate cancer cells.
Cancer letters 2006;234(2):109-23.
2006: Yosef Shaul; Rony Seger
ERK1c regulates Golgi fragmentation during mitosis.
The Journal of cell biology 2006;172(6):885-97.
2006: Seunghee Yoon; Rony Seger
The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions.
Growth factors (Chur, Switzerland) 2006;24(1):21-44.
2006: Yoav Shaul; Rony Seger
The detection of MAPK signaling.
Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.] 2006;Chapter 18():Unit 18.12.
2005: Yoav Shaul; Rony Seger
The detection of MAPK signaling.
Current protocols in cell biology / editorial board, Juan S. Bonifacino ... [et al.] 2005;Chapter 14():Unit 14.3.
2005: Hadara Rubinfeld; Rony Seger
The ERK cascade: a prototype of MAPK signaling.
Molecular biotechnology 2005;31(2):151-74.
2005: Rebeca Tarrab-Hazdai; Tamar Hanoch; Sung Ho Jeon; Henya Pauli; Daniel Gold; Ruth Arnon; Rony Seger
Ecto- and exo-protein kinases in Schistosoma mansoni: regulation of surface phosphorylation by acetylcholine and identification of the alpha subunit of CKII as a major secreted protein kinase.
The Journal of parasitology 2005;91(4):756-63.
2005: Yehudit Posen; Vyacheslav Kalchenko; Rony Seger; Alexander Brandis; Avigdor Scherz; Yoram Salomon
Manipulation of redox signaling in mammalian cells enabled by controlled photogeneration of reactive oxygen species.
Journal of cell science 2005;118(Pt 9):1957-69.
2005: Eran Perlson; Shlomit Hanz; Keren Ben-Yaakov; Yael Segal-Ruder; Rony Seger; Mike Fainzilber
Vimentin-dependent spatial translocation of an activated MAP kinase in injured nerve.
Neuron 2005;45(5):715-26.
2005: Galia Maik-Rachline; Shmuel Shaltiel; Rony Seger
Extracellular phosphorylation converts pigment epithelium-derived factor from a neurotrophic to an antiangiogenic factor.
Blood 2005;105(2):670-8.
2005: Dana Chuderland; Rony Seger
Protein-protein interactions in the regulation of the extracellular signal-regulated kinase.
Molecular biotechnology 2005;29(1):57-74.
2005: Isabelle Petit; Polina Goichberg; Asaf Spiegel; Amnon Peled; Chaya Brodie; Rony Seger; Arnon Nagler; Ronen Alon; Tsvee Lapidot
Atypical PKC-zeta regulates SDF-1-mediated migration and development of human CD34+ progenitor cells.
The Journal of clinical investigation 2005;115(1):168-76.
2004: Daniel M Aebersold; Yosef Shaul; Yuval Yung; Nirit Yarom; Zhong Yao; Tamar Hanoch; Rony Seger
Extracellular signal-regulated kinase 1c (ERK1c), a novel 42-kilodalton ERK, demonstrates unique modes of regulation, localization, and function.
Molecular and cellular biology 2004;24(22):10000-15.
2004: Sarah Kraus; Gal Levy; Tamar Hanoch; Zvi Naor; Rony Seger
Gonadotropin-releasing hormone induces apoptosis of prostate cancer cells: role of c-Jun NH2-terminal kinase, protein kinase B, and extracellular signal-regulated kinase pathways.
Cancer research 2004;64(16):5736-44.
2004: David Bonfil; Dana Chuderland; Sarah Kraus; David Shahbazian; Ilan Friedberg; Rony Seger; Zvi Naor
Extracellular signal-regulated kinase, Jun N-terminal kinase, p38, and c-Src are involved in gonadotropin-releasing hormone-stimulated activity of the glycoprotein hormone follicle-stimulating hormone beta-subunit promoter.
Endocrinology 2004;145(5):2228-44.
2004: ziv raviv; Eyal Kalie; Rony Seger
MEK5 and ERK5 are localized in the nuclei of resting as well as stimulated cells, while MEKK2 translocates from the cytosol to the nucleus upon stimulation.
Journal of cell science 2004;117(Pt 9):1773-84.
2004: Yosef Shaul; Rony Seger
Use of inhibitors in the study of MAPK signaling.
Methods in molecular biology (Clifton, N.J.) 2004;250():113-26.
2004: Sarah Kraus; Rony Seger
Determination of ERK activity: antiphospho-ERK antibodies, in vitro phosphorylation, and in-gel kinase assay.
Methods in molecular biology (Clifton, N.J.) 2004;250():29-48.
2004: Hadara Rubinfeld; Rony Seger
The ERK cascade as a prototype of MAPK signaling pathways.
Methods in molecular biology (Clifton, N.J.) 2004;250():1-28.
2003: Dalia Rivenzon-Segal; Swetlana Boldin-Adamsky; Dalia Seger; Rony Seger; Hadassa Degani
Glycolysis and glucose transporter 1 as markers of response to hormonal therapy in breast cancer.
International journal of cancer. Journal international du cancer 2003;107(2):177-82.
2003: Sarah Kraus; Outhiriaradjou Benard; Zvi Naor; Rony Seger
c-Src is activated by the epidermal growth factor receptor in a pathway that mediates JNK and ERK activation by gonadotropin-releasing hormone in COS7 cells.
The Journal of biological chemistry 2003;278(35):32618-30.
2003: Kimihisa Tajima; Ada Dantes; Zhong Yao; Ksenia Sorokina; Fumikazu Kotsuji; Rony Seger; Abraham Amsterdam
Down-regulation of steroidogenic response to gonadotropins in human and rat preovulatory granulosa cells involves mitogen-activated protein kinase activation and modulation of DAX-1 and steroidogenic factor-1.
The Journal of clinical endocrinology and metabolism 2003;88(5):2288-99.
2003: Abraham Amsterdam; Kimihisa Tajima; V Frajese; Rony Seger
Analysis of signal transduction stimulated by gonadotropins in granulosa cells.
Molecular and cellular endocrinology 2003;202(1-2):77-80.
2003: Liat Ben-Yehoshua Josefsberg; Dalia Galiani; Shlomi Lazar; Orit Kaufman; Rony Seger; Nava Dekel
Maturation-promoting factor governs mitogen-activated protein kinase activation and interphase suppression during meiosis of rat oocytes.
Biology of reproduction 2003;68(4):1282-90.
2003: Dagan Harris; Dana Chuderland; David Bonfil; Sarah Kraus; Rony Seger; Zvi Naor
Extracellular signal-regulated kinase and c-Src, but not Jun N-terminal kinase, are involved in basal and gonadotropin-releasing hormone-stimulated activity of the glycoprotein hormone alpha-subunit promoter.
Endocrinology 2003;144(2):612-22.
2002: Moshe Oren; Alexander Damalas; Tanya Gottlieb; Dan Michael; Jan Taplick; Juan Fernando Martinez Leal; Ruth Maya; Miri Moas; Rony Seger; Yoichi Taya; Avri Ben-Ze'ev
Regulation of p53: intricate loops and delicate balances.
Annals of the New York Academy of Sciences 2002;973():374-83.
2002: Haikun Shi; Carol Asher; Yuval Yung; Luba Kligman; Eitan Reuveny; Rony Seger; Haim Garty
Casein kinase 2 specifically binds to and phosphorylates the carboxy termini of ENaC subunits.
European journal of biochemistry / FEBS 2002;269(18):4551-8.
2002: Moshe Oren; Alexander Damalas; Tanya Gottlieb; Dan Michael; Jan Taplick; Juan Fernando Martinez Leal; Ruth Maya; Miri Moas; Rony Seger; Yoichi Taya; Avri Ben-Ze'ev
Regulation of p53: intricate loops and delicate balances.
Biochemical pharmacology 2002;64(5-6):865-71.
2002: Haikun Shi; Carol Asher; Alexandre Chigaev; Yuval Yung; Eitan Reuveny; Rony Seger; Haim Garty
Interactions of beta and gamma ENaC with Nedd4 can be facilitated by an ERK-mediated phosphorylation.
The Journal of biological chemistry 2002;277(16):13539-47.
2002: Dagan Harris; David Bonfil; Dana Chuderland; Sarah Kraus; Rony Seger; Zvi Naor
Activation of MAPK cascades by GnRH: ERK and Jun N-terminal kinase are involved in basal and GnRH-stimulated activity of the glycoprotein hormone LHbeta-subunit promoter.
Endocrinology 2002;143(3):1018-25.
2002: Abraham Amsterdam; Tamar Hanoch; Ada Dantes; Kimihisa Tajima; Jerome F Strauss; Rony Seger
Mechanisms of gonadotropin desensitization.
Molecular and cellular endocrinology 2002;187(1-2):69-74.
2002: Tanya Gottlieb; Juan Fernando Martinez Leal; Rony Seger; Yoichi Taya; Moshe Oren
Cross-talk between Akt, p53 and Mdm2: possible implications for the regulation of apoptosis.
Oncogene 2002;21(8):1299-303.
2002: Anat Bar-Shira; Sharon Rashi-Elkeles; Liat Zlochover; Lilach Moyal; Nechama I Smorodinsky; Rony Seger; Yosef Shiloh
ATM-dependent activation of the gene encoding MAP kinase phosphatase 5 by radiomimetic DNA damage.
Oncogene 2002;21(5):849-55.
2001: Z Yao; I Flash; ziv raviv; Y Yung; Y Asscher; S Pleban; Rony Seger
Non-regulated and stimulated mechanisms cooperate in the nuclear accumulation of MEK1.
Oncogene 2001;20(52):7588-96.
2001: Sarah Kraus; Zvi Naor; Rony Seger
Intracellular signaling pathways mediated by the gonadotropin-releasing hormone (GnRH) receptor.
Archives of medical research 2001;32(6):499-509.
2001: Yuval Yung; Zhong Yao; D M Aebersold; Tamar Hanoch; Rony Seger
Altered regulation of ERK1b by MEK1 and PTP-SL and modified Elk1 phosphorylation by ERK1b are caused by abrogation of the regulatory C-terminal sequence of ERKs.
The Journal of biological chemistry 2001;276(38):35280-9.
2001: I Wolf; Hadara Rubinfeld; S Yoon; G Marmor; Tamar Hanoch; Rony Seger
Involvement of the activation loop of ERK in the detachment from cytosolic anchoring.
The Journal of biological chemistry 2001;276(27):24490-7.
2001: Alexandre Chigaev; G Lu; Haikun Shi; Carol Asher; R Xu; Hedva Latter; Rony Seger; Haim Garty; Eitan Reuveny
In vitro phosphorylation of COOH termini of the epithelial Na(+) channel and its effects on channel activity in Xenopus oocytes.
American journal of physiology. Renal physiology 2001;280(6):F1030-6.
2001: Dalia Seger; Rony Seger; Shmuel Shaltiel
The CK2 phosphorylation of vitronectin. Promotion of cell adhesion via the alpha(v)beta 3-phosphatidylinositol 3-kinase pathway.
The Journal of biological chemistry 2001;276(20):16998-7006.
2001: Z Yao; Rony Seger
Immunological detection of phosphorylation.
Current protocols in cell biology / editorial board, Juan S. Bonifacino ... [et al.] 2001;Chapter 14():Unit 14.2.
2001: Rony Seger; Tamar Hanoch; R Rosenberg; Ada Dantes; W E Merz; Jerome F Strauss; Abraham Amsterdam
The ERK signaling cascade inhibits gonadotropin-stimulated steroidogenesis.
The Journal of biological chemistry 2001;276(17):13957-64.
2001: Sarah Kraus; Rony Seger; Zvi Fishelson
Involvement of the ERK mitogen-activated protein kinase in cell resistance to complement-mediated lysis.
Clinical and experimental immunology 2001;123(3):366-74.
2001: Outhiriaradjou Benard; Zvi Naor; Rony Seger
Role of dynamin, Src, and Ras in the protein kinase C-mediated activation of ERK by gonadotropin-releasing hormone.
The Journal of biological chemistry 2001;276(7):4554-63.
2001: Annette Brand; S Gil; Rony Seger; Ephraim Yavin
Lipid constituents in oligodendroglial cells alter susceptibility to H2O2-induced apoptotic cell death via ERK activation.
Journal of neurochemistry 2001;76(3):910-8.
2001: Sarah S Bacus; Andrei V Gudkov; M Lowe; Ljuba Lyass; Y Yung; A P Komarov; Khandan Keyomarsi; Yosef Yarden; Rony Seger
Taxol-induced apoptosis depends on MAP kinase pathways (ERK and p38) and is independent of p53.
Oncogene 2001;20(2):147-55.
2001: Sharon Shacham; Dagan Harris; H Ben-Shlomo; I Cohen; David Bonfil; F Przedecki; Hadas Lewy; Israel E Ashkenazi; Rony Seger; Zvi Naor
Mechanism of GnRH receptor signaling on gonadotropin release and gene expression in pituitary gonadotrophs.
Vitamins and hormones 2001;63():63-90.
2000: Y Chen; X Li; Veraragavan Eswarakumar; Rony Seger; Peter Lonai
Fibroblast growth factor (FGF) signaling through PI 3-kinase and Akt/PKB is required for embryoid body differentiation.
Oncogene 2000;19(33):3750-6.
2000: Yuval Yung; Zhong Yao; Tamar Hanoch; Rony Seger
ERK1b, a 46-kDa ERK isoform that is differentially regulated by MEK.
The Journal of biological chemistry 2000;275(21):15799-808.
2000: Meir Shinitzky; Rachel Haimovitz; M Nemas; N Cahana; Ramanaiah Mamillapalli; Rony Seger
Induction of intracellular signalling by cyclic glycerophosphates and their deoxy analogues.
European journal of biochemistry / FEBS 2000;267(9):2547-54.
2000: Zvi Naor; Outhiriaradjou Benard; Rony Seger
Activation of MAPK cascades by G-protein-coupled receptors: the case of gonadotropin-releasing hormone receptor.
Trends in endocrinology and metabolism: TEM 2000;11(3):91-9.
2000: Zhong Yao; Y Dolginov; Tamar Hanoch; Yuval Yung; Gabriela Ridner; Zeev Lando; Dorit Zharhary; Rony Seger
Detection of partially phosphorylated forms of ERK by monoclonal antibodies reveals spatial regulation of ERK activity by phosphatases.
FEBS letters 2000;468(1):37-42.
1999: Hadara Rubinfeld; Tamar Hanoch; Rony Seger
Identification of a cytoplasmic-retention sequence in ERK2.
The Journal of biological chemistry 1999;274(43):30349-52.
1999: Keren Paz; Yan-Fang Liu; Hagai Shorer; Rina Hemi; Derek LeRoith; M Quan; Hannah Kanety; Rony Seger; Yehiel Zick
Phosphorylation of insulin receptor substrate-1 (IRS-1) by protein kinase B positively regulates IRS-1 function.
The Journal of biological chemistry 1999;274(40):28816-22.
1999: Tamar Sapir; A Cahana; Rony Seger; Sergei Nekhai; Orly Reiner
LIS1 is a microtubule-associated phosphoprotein.
European journal of biochemistry / FEBS 1999;265(1):181-8.
1999: Y Arava; Rony Seger; Michael D Walker
GRFbeta, a novel regulator of calcium signaling, is expressed in pancreatic beta cells and brain.
The Journal of biological chemistry 1999;274(35):24449-52.
1999: Rong Xu; Rony Seger; Israel Pecht
Cutting edge: extracellular signal-regulated kinase activates syk: a new potential feedback regulation of Fc epsilon receptor signaling.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(3):1110-4.
1999: Sharon Shacham; M N Cheifetz; Hadas Lewy; Israel E Ashkenazi; Oren M Becker; Rony Seger; Zvi Naor
Mechanism of GnRH receptor signaling: from the membrane to the nucleus.
Annales d'endocrinologie 1999;60(2):79-88.
1999: Hadassa Waterman; Iris Alroy; S Strano; Rony Seger; Yosef Yarden
The C-terminus of the kinase-defective neuregulin receptor ErbB-3 confers mitogenic superiority and dictates endocytic routing.
The EMBO journal 1999;18(12):3348-58.
1999: Irit Shefler; Rony Seger; Ronit Sagi-Eisenberg
Gi-mediated activation of mitogen-activated protein kinase (MAPK) pathway by receptor mimetic basic secretagogues of connective tissue-type mast cells: bifurcation of arachidonic acid-induced release upstream of MAPK.
The Journal of pharmacology and experimental therapeutics 1999;289(3):1654-61.
1999: Iris Alroy; L Soussan; Rony Seger; Yosef Yarden
Neu differentiation factor stimulates phosphorylation and activation of the Sp1 transcription factor.
Molecular and cellular biology 1999;19(3):1961-72.
1999: Anat Oren; A Herschkovitz; Iris Ben-Dror; Vered Holdengreber; Yehuda Ben-Shaul; Rony Seger; Lily Vardimon
The cytoskeletal network controls c-Jun expression and glucocorticoid receptor transcriptional activity in an antagonistic and cell-type-specific manner.
Molecular and cellular biology 1999;19(3):1742-50.
1999: M A Silverman; Outhiriaradjou Benard; Hanna Jaaro; Amir Rattner; Y Citri; Rony Seger
CPG16, a novel protein serine/threonine kinase downstream of cAMP-dependent protein kinase.
The Journal of biological chemistry 1999;274(5):2631-6.
1998: Ronit Pinkas-Kramarski; Maya Shelly; B C Guarino; Ling Mei Wang; Ljuba Lyass; Iris Alroy; M Alimandi; A Kuo; JD Moyer; Sara Lavi; Miriam Eisenstein; BJ Ratzkin; Rony Seger; Sarah S Bacus; JH Pierce; glenn andrews; Yosef Yarden; M Alamandi
ErbB tyrosine kinases and the two neuregulin families constitute a ligand-receptor network.
Molecular and cellular biology 1998;18(10):6090-101.
1998: Justin P Kumar; M Tio; Frank Hsiung; S Akopyan; Limor Gabay; Rony Seger; Ben-Zion Shilo; Kevin Moses
Dissecting the roles of the Drosophila EGF receptor in eye development and MAP kinase activation.
Development (Cambridge, England) 1998;125(19):3875-85.
1998: N L Levi; Tamar Hanoch; Outhiriaradjou Benard; M Rozenblat; Dagan Harris; N Reiss; Zvi Naor; Rony Seger
Stimulation of Jun N-terminal kinase (JNK) by gonadotropin-releasing hormone in pituitary alpha T3-1 cell line is mediated by protein kinase C, c-Src, and CDC42.
Molecular endocrinology (Baltimore, Md.) 1998;12(6):815-24.
1998: D Hevroni; Amir Rattner; M Bundman; D Lederfein; A Gabarah; M Mangelus; M A Silverman; H Kedar; C Naor; M Kornuc; Tamar Hanoch; Rony Seger; Lars E Theill; E Nedivi; G Richter-Levin; Y Citri
Hippocampal plasticity involves extensive gene induction and multiple cellular mechanisms.
Journal of molecular neuroscience : MN 1998;10(2):75-98.
1998: Einat Sadot; Hanna Jaaro; Rony Seger; Irith Ginzburg
Ras-signaling pathways: positive and negative regulation of tau expression in PC12 cells.
Journal of neurochemistry 1998;70(1):428-31.
1997: Limor Gabay; Rony Seger; Ben-Zion Shilo
MAP kinase in situ activation atlas during Drosophila embryogenesis.
Development (Cambridge, England) 1997;124(18):3535-41.
1997: Limor Gabay; Rony Seger; Ben-Zion Shilo
In situ activation pattern of Drosophila EGF receptor pathway during development.
Science (New York, N.Y.) 1997;277(5329):1103-6.
1997: Yuval Yung; Y Dolginov; Zhong Yao; Hadara Rubinfeld; D Michael; Tamar Hanoch; E Roubini; Zeev Lando; Dorit Zharhary; Rony Seger
Detection of ERK activation by a novel monoclonal antibody.
FEBS letters 1997;408(3):292-6.
1997: Hanna Jaaro; Hadara Rubinfeld; Tamar Hanoch; Rony Seger
Nuclear translocation of mitogen-activated protein kinase kinase (MEK1) in response to mitogenic stimulation.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(8):3742-7.
1997: N Reiss; L N Llevi; Sharon Shacham; Dagan Harris; Rony Seger; Zvi Naor
Mechanism of mitogen-activated protein kinase activation by gonadotropin-releasing hormone in the pituitary of alphaT3-1 cell line: differential roles of calcium and protein kinase C.
Endocrinology 1997;138(4):1673-82.
1997: Rachel Goldman; Uriel Zor; R Meller; Sandra Moshonov; G Fürstenberger; Rony Seger
Activation of MAP kinases, cPLA2 and reactive oxygen species formation by EGF and calcium mobilizing agonists in a human keratinocyte cell line.
Advances in experimental medicine and biology 1997;407():289-93.
1996: Ronit Pinkas-Kramarski; L Soussan; Hadassa Waterman; Gil Levkowitz; Iris Alroy; LN Klapper; S Lavi; Rony Seger; B J Ratzkin; Michael Sela; Yosef Yarden
Diversification of Neu differentiation factor and epidermal growth factor signaling by combinatorial receptor interactions.
The EMBO journal 1996;15(10):2452-67.
1996: Devarajan Karunagaran; E Tzahar; Roger R Beerli; X Chen; Diana Graus Porta; B J Ratzkin; Rony Seger; Nancy E Hynes; Yosef Yarden
ErbB-2 is a common auxiliary subunit of NDF and EGF receptors: implications for breast cancer.
The EMBO journal 1996;15(2):254-64.
1995: Rony Seger; Y Biener; R Feinstein; Tamar Hanoch; A Gazit; Yehiel Zick
Differential activation of mitogen-activated protein kinase and S6 kinase signaling pathways by 12-O-tetradecanoylphorbol-13-acetate (TPA) and insulin. Evidence for involvement of a TPA-stimulated protein-tyrosine kinase.
The Journal of biological chemistry 1995;270(47):28325-30.
1995: Zvi Naor; Sharon Shacham; Dagan Harris; Rony Seger; N Reiss
Signal transduction of the gonadotropin releasing hormone (GnRH) receptor: cross-talk of calcium, protein kinase C (PKC), and arachidonic acid.
Cellular and molecular neurobiology 1995;15(5):527-44.
1995: R Schweitzer; M Shaharabany; Rony Seger; Ben-Zion Shilo
Secreted Spitz triggers the DER signaling pathway and is a limiting component in embryonic ventral ectoderm determination.
Genes & development 1995;9(12):1518-29.
1995: Rony Seger; Edwin G Krebs
The MAPK signaling cascade.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1995;9(9):726-35.
1989: Rony Seger; Yehiel Zick; Shmuel Shaltiel
Studying the structure of the intracellular moiety of the insulin receptor with a kinase-splitting membranal proteinase.
The EMBO journal 1989;8(2):435-40.
1988: Rony Seger; Yosef Yarden; O Kashles; D Goldblatt; J Schlessinger; Shmuel Shaltiel
The epidermal growth factor receptor as a substrate for a kinase-splitting membranal proteinase.
The Journal of biological chemistry 1988;263(7):3496-500.