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Didier Blanot

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Chemicals & Drugs

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Escherichia coli

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Mireille Hervé; Andreja Kovač; Dominique Mengin-Lecreulx; Delphine Patin; Hélène Barreteau; Boris Brus; Cécile Cardoso; Stanislav Gobec; Didier Blanot
Synthetic tripeptides as alternate substrates of murein peptide ligase (Mpl).
Matthieu Fonvielle; Maxime Lecerf; Dénia Mellal; Dominique Mengin-Lecreulx; Delphine Patin; Marco Santarem; Matthieu Sollogoub; Michel Arthur; Didier Blanot; Ahmed Bouhss; Mélanie Ethève-Quelquejeu
Efficient access to peptidyl-RNA conjugates for picomolar inhibition of non-ribosomal FemX(Wv) aminoacyl transferase.
Thierry Touzé; Delphine Patin; Emmanuelle Sacco; Michel Arthur; Aurélie Barnéoud-Arnoulet; Hélène Barreteau; Didier Blanot; Ahmed Bouhss; Denis Duché; Meriem El Ghachi; Roland Lloubès; Dominique Mengin-Lecreulx
Colicin M, a peptidoglycan lipid-II-degrading enzyme: potential use for antibacterial means?

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All Publications

2013: Mireille Hervé; Andreja Kovač; Dominique Mengin-Lecreulx; Delphine Patin; Hélène Barreteau; Boris Brus; Cécile Cardoso; Stanislav Gobec; Didier Blanot
Synthetic tripeptides as alternate substrates of murein peptide ligase (Mpl).
Biochimie 2013;95(6):1120-6.
2013: Matthieu Fonvielle; Maxime Lecerf; Dénia Mellal; Dominique Mengin-Lecreulx; Delphine Patin; Marco Santarem; Matthieu Sollogoub; Michel Arthur; Didier Blanot; Ahmed Bouhss; Mélanie Ethève-Quelquejeu
Efficient access to peptidyl-RNA conjugates for picomolar inhibition of non-ribosomal FemX(Wv) aminoacyl transferase.
Chemistry (Weinheim an der Bergstrasse, Germany) 2013;19(4):1357-63.
2012: Thierry Touzé; Delphine Patin; Emmanuelle Sacco; Michel Arthur; Aurélie Barnéoud-Arnoulet; Hélène Barreteau; Didier Blanot; Ahmed Bouhss; Denis Duché; Meriem El Ghachi; Roland Lloubès; Dominique Mengin-Lecreulx
Colicin M, a peptidoglycan lipid-II-degrading enzyme: potential use for antibacterial means?
Biochemical Society transactions 2012;40(6):1522-7.
2012: Hélène Barreteau; Didier Blanot; Ahmed Bouhss; Martine Fourgeaud; Marc Graille; Nathalie Josseaume; Jean-Luc Mainardi; Dominique Mengin-Lecreulx; Delphine Patin; Mounira Tiouajni; Michel Arthur; Herman van Tilbeurgh; Thierry Touzé
Functional and structural characterization of PaeM, a colicin M-like bacteriocin produced by Pseudomonas aeruginosa.
The Journal of biological chemistry 2012;287(44):37395-405.
2012: Hélène Barreteau; Audrey Boniface; Stanislav Gobec; Mireille Hervé; Jan Humljan; Danijel Kikelj; Dominique Mengin-Lecreulx; Lucija Peterlin-Mašič; Izidor Sosič; Tihomir Tomašić; Samo Turk; Nace Zidar; Didier Blanot
MurD enzymes from different bacteria: evaluation of inhibitors.
Biochemical pharmacology 2012;84(5):625-32.
2012: Hélène Barreteau; Didier Blanot; Ahmed Bouhss; Mark Brooks; Denis Duché; Meriem El Ghachi; Fabien Gérard; Roland Lloubès; Delphine Patin; Emmanuelle Sacco; Thierry Touzé; Herman van Tilbeurgh; Michel Arthur; Aurélie Barnéoud-Arnoulet; Dominique Mengin-Lecreulx
Characterization of colicin M and its orthologs targeting bacterial cell wall peptidoglycan biosynthesis.
Microbial drug resistance (Larchmont, N.Y.) 2012;18(3):222-9.
2012: Delphine Patin; Julieanne Bostock; Ian Chopra; Dominique Mengin-Lecreulx; Didier Blanot
Biochemical characterisation of the chlamydial MurF ligase, and possible sequence of the chlamydial peptidoglycan pentapeptide stem.
Archives of microbiology 2012;194(6):505-12.
2012: Delphine Patin; Thierry Touzé; Michel Arthur; Geneviève Auger; Hélène Barreteau; Ahmed Bouhss; Muriel Crouvoisier; Sophie Magnet; Dominique Mengin-Lecreulx; Didier Blanot
Colicin M hydrolyses branched lipids II from Gram-positive bacteria.
Biochimie 2012;94(4):985-90.
2012: Tihomir Tomašić; Didier Blanot; Stanislav Gobec; Danijel Kikelj; Gerhard Klebe; Andreja Kovač; Lucija Peterlin Mašič
Virtual screening for potential inhibitors of bacterial MurC and MurD ligases.
Journal of molecular modeling 2012;18(3):1063-72.
2011: Nace Zidar; Roman Šink; Didier Blanot; Carlos A Contreras-Martel; Andréa Dessen; Stanislav Gobec; Andreja Kovač; Lucija Peterlin Mašič; Delphine Patin; Manica Müller Premru; Tihomir Tomašić; Anamarija Zega; Danijel Kikelj
New 5-benzylidenethiazolidin-4-one inhibitors of bacterial MurD ligase: design, synthesis, crystal structures, and biological evaluation.
European journal of medicinal chemistry 2011;46(11):5512-23.
2011: Tihomir Tomašić; Mihael Simčič; Didier Blanot; Stanislav Gobec; Simona Golic Grdadolnik; Danijel Kikelj; Andreja Kovač; Lucija Peterlin Mašič
Novel 2-thioxothiazolidin-4-one inhibitors of bacterial MurD ligase targeting D-Glu- and diphosphate-binding sites.
European journal of medicinal chemistry 2011;46(9):3964-75.
2011: Tihomir Tomasić; Anamarija Zega; Nace Zidar; Manica Müller-Premru; Roman Sink; Didier Blanot; Carlos A Contreras-Martel; Andréa Dessen; Stanislav Gobec; Danijel Kikelj; Andreja Kovac; Lucija Peterlin Masic
Structure-based design of a new series of D-glutamic acid based inhibitors of bacterial UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase (MurD).
Journal of medicinal chemistry 2011;54(13):4600-10.
2011: Izidor Sosič; Hélène Barreteau; Mihael Simčič; Roman Sink; Jozko Cesar; Anamarija Zega; Simona Golic Grdadolnik; Carlos A Contreras-Martel; Andréa Dessen; Ana Amoroso; Bernard Joris; Didier Blanot; Stanislav Gobec
Second-generation sulfonamide inhibitors of D-glutamic acid-adding enzyme: activity optimisation with conformationally rigid analogues of D-glutamic acid.
European journal of medicinal chemistry 2011;46(7):2880-94.
2011: Fabien Gérard; Mark A Brooks; Hélène Barreteau; Thierry Touzé; Marc Graille; Ahmed Bouhss; Didier Blanot; Herman van Tilbeurgh; Dominique Mengin-Lecreulx
X-ray structure and site-directed mutagenesis analysis of the Escherichia coli colicin M immunity protein.
Journal of bacteriology 2011;193(1):205-14.
2010: Delphine Patin; Audrey Boniface; Andreja Kovač; Mireille Hervé; Sébastien Dementin; Hélène Barreteau; Dominique Mengin-Lecreulx; Didier Blanot
Purification and biochemical characterization of Mur ligases from Staphylococcus aureus.
Biochimie 2010;92(12):1793-800.
2010: Nace Zidar; Tihomir Tomasić; Roman Sink; Veronika Rupnik; Andreja Kovac; Samo Turk; Delphine Patin; Didier Blanot; Carlos A Contreras-Martel; Andréa Dessen; Manica Müller-Premru; Anamarija Zega; Stanislav Gobec; Lucija Peterlin-Masic; Danijel Kikelj
Discovery of novel 5-benzylidenerhodanine and 5-benzylidenethiazolidine-2,4-dione inhibitors of MurD ligase.
Journal of medicinal chemistry 2010;53(18):6584-94.
2010: Hélène Barreteau; Ahmed Bouhss; Fabien Gérard; Denis Duché; Boubekeur Boussaid; Didier Blanot; Roland Lloubès; Dominique Mengin-Lecreulx; Thierry Touzé
Deciphering the catalytic domain of colicin M, a peptidoglycan lipid II-degrading enzyme.
The Journal of biological chemistry 2010;285(16):12378-89.
2010: Emmanuelle Sacco; Jean-Emmanuel Hugonnet; Nathalie Josseaume; Julie Cremniter; Lionel Dubost; Arul Marie; Delphine Patin; Didier Blanot; Louis B Rice; Jean-Luc Mainardi; Michel Arthur
Activation of the L,D-transpeptidation peptidoglycan cross-linking pathway by a metallo-D,D-carboxypeptidase in Enterococcus faecium.
Molecular microbiology 2010;75(4):874-85.
2010: Tihomir Tomasić; Nace Zidar; Andreja Kovac; Samo Turk; Mihael Simcic; Didier Blanot; Manica Müller-Premru; Metka Filipic; Simona Golic Grdadolnik; Anamarija Zega; Marko Anderluh; Stanislav Gobec; Danijel Kikelj; Lucija Peterlin-Masic
5-Benzylidenethiazolidin-4-ones as multitarget inhibitors of bacterial Mur ligases.
ChemMedChem 2010;5(2):286-95.
2009: Delphine Patin; Julieanne M Bostock; Didier Blanot; Dominique Mengin-Lecreulx; Ian Chopra
Functional and biochemical analysis of the Chlamydia trachomatis ligase MurE.
Journal of bacteriology 2009;191(24):7430-5.
2009: Matej Sova; Andreja Kovac; Samo Turk; Martina Hrast; Didier Blanot; Stanislav Gobec
Phosphorylated hydroxyethylamines as novel inhibitors of the bacterial cell wall biosynthesis enzymes MurC to MurF.
Bioorganic chemistry 2009;37(6):217-22.
2009: Bayan Al-Dabbagh; Didier Blanot; Dominique Mengin-Lecreulx; Ahmed Bouhss
Preparative enzymatic synthesis of polyprenyl-pyrophosphoryl-N-acetylglucosamine, an essential lipid intermediate for the biosynthesis of various bacterial cell envelope polymers.
Analytical biochemistry 2009;391(2):163-5.
2009: Audrey Boniface; Claudine Parquet; Michel Arthur; Dominique Mengin-Lecreulx; Didier Blanot
The elucidation of the structure of Thermotoga maritima peptidoglycan reveals two novel types of cross-link.
The Journal of biological chemistry 2009;284(33):21856-62.
2009: Hélène Barreteau; Ahmed Bouhss; Martine Fourgeaud; Jean-Luc Mainardi; Thierry Touzé; Fabien Gérard; Didier Blanot; Michel Arthur; Dominique Mengin-Lecreulx
Human- and plant-pathogenic Pseudomonas species produce bacteriocins exhibiting colicin M-like hydrolase activity towards peptidoglycan precursors.
Journal of bacteriology 2009;191(11):3657-64.
2009: Samo Turk; Andreja Kovac; Audrey Boniface; Julieanne M Bostock; Ian Chopra; Didier Blanot; Stanislav Gobec
Discovery of new inhibitors of the bacterial peptidoglycan biosynthesis enzymes MurD and MurF by structure-based virtual screening.
Bioorganic & medicinal chemistry 2009;17(5):1884-9.
2009: Hélène Barreteau; Sophie Magnet; Meriem El Ghachi; Thierry Touzé; Michel Arthur; Dominique Mengin-Lecreulx; Didier Blanot
Quantitative high-performance liquid chromatography analysis of the pool levels of undecaprenyl phosphate and its derivatives in bacterial membranes.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2009;877(3):213-20.
2009: Tihomir Tomasić; Nace Zidar; Veronika Rupnik; Andreja Kovac; Didier Blanot; Stanislav Gobec; Danijel Kikelj; Lucija Peterlin Masic
Synthesis and biological evaluation of new glutamic acid-based inhibitors of MurD ligase.
Bioorganic & medicinal chemistry letters 2009;19(1):153-7.
2009: Nhat Khai Bui; Joe Gray; Heinz Schwarz; Peter Schumann; Didier Blanot; Waldemar Vollmer
The peptidoglycan sacculus of Myxococcus xanthus has unusual structural features and is degraded during glycerol-induced myxospore development.
Journal of bacteriology 2009;191(2):494-505.
2008: Roman Sink; Andreja Kovac; Tihomir Tomasić; Veronika Rupnik; Audrey Boniface; Julieanne Bostock; Ian Chopra; Didier Blanot; Lucija Peterlin Masic; Stanislav Gobec; Anamarija Zega
Synthesis and biological evaluation of N-acylhydrazones as inhibitors of MurC and MurD ligases.
ChemMedChem 2008;3(9):1362-70.
2008: Bayan Al-Dabbagh; Xavier Henry; Meriem El Ghachi; Geneviève Auger; Didier Blanot; Claudine Parquet; Dominique Mengin-Lecreulx; Ahmed Bouhss
Active site mapping of MraY, a member of the polyprenyl-phosphate N-acetylhexosamine 1-phosphate transferase superfamily, catalyzing the first membrane step of peptidoglycan biosynthesis.
Biochemistry 2008;47(34):8919-28.
2008: Thierry Touzé; Didier Blanot; Dominique Mengin-Lecreulx
Substrate specificity and membrane topology of Escherichia coli PgpB, an undecaprenyl pyrophosphate phosphatase.
The Journal of biological chemistry 2008;283(24):16573-83.
2008: Nico Marr; Alina Tirsoaga; Didier Blanot; Rachel Fernandez; Martine Caroff
Glucosamine found as a substituent of both phosphate groups in Bordetella lipid A backbones: role of a BvgAS-activated ArnT ortholog.
Journal of bacteriology 2008;190(12):4281-90.
2008: Marie Lavollay; Michel Arthur; Martine Fourgeaud; lionel dubost; Arul Marie; Nicolas Veziris; Didier Blanot; Laurent Gutmann; Jean-Luc Mainardi
The peptidoglycan of stationary-phase Mycobacterium tuberculosis predominantly contains cross-links generated by L,D-transpeptidation.
Journal of bacteriology 2008;190(12):4360-6.
2008: Cédric Absalon; Kassem Hamze; Didier Blanot; Claude Frehel; Rut Carballido-Lopez; Barry I Holland; Jean Van Heijenoort; Simone J Séror
The GTPase CpgA is implicated in the deposition of the peptidoglycan sacculus in Bacillus subtilis.
Journal of bacteriology 2008;190(10):3786-90.
2008: Hélène Barreteau; Andreja Kovac; Audrey Boniface; Martin Sova; Stanislav Gobec; Didier Blanot
Cytoplasmic steps of peptidoglycan biosynthesis.
FEMS microbiology reviews 2008;32(2):168-207.
2008: Waldemar Vollmer; Didier Blanot; Miguel A de Pedro
Peptidoglycan structure and architecture.
FEMS microbiology reviews 2008;32(2):149-67.
2008: Michel Nuevo; Geneviève Auger; Didier Blanot; Louis d'Hendecourt
A detailed study of the amino acids produced from the vacuum UV irradiation of interstellar ice analogs.
Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 2008;38(1):37-56.
2008: Rok Frlan; Andreja Kovac; Didier Blanot; Stanislav Gobec; Slavko Pecar; Ales Obreza
Design and synthesis of novel N-benzylidenesulfonohydrazide inhibitors of MurC and MurD as potential antibacterial agents.
Molecules (Basel, Switzerland) 2008;13(1):11-30.
2007: Muriel Crouvoisier; Geneviève Auger; Didier Blanot; Dominique Mengin-Lecreulx
Role of the amino acid invariants in the active site of MurG as evaluated by site-directed mutagenesis.
Biochimie 2007;89(12):1498-508.
2007: Miha Kotnik; Jan Humljan; Carlos A Contreras-Martel; Marko Oblak; Katja Kristan; Mireille Hervé; Didier Blanot; Uros Urleb; Stanislav Gobec; Andréa Dessen; Tom Solmajer
Structural and functional characterization of enantiomeric glutamic acid derivatives as potential transition state analogue inhibitors of MurD ligase.
Journal of molecular biology 2007;370(1):107-15.
2007: Mireille Hervé; Audrey Boniface; Stanislav Gobec; Didier Blanot; Dominique Mengin-Lecreulx
Biochemical characterization and physiological properties of Escherichia coli UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase.
Journal of bacteriology 2007;189(11):3987-95.
2007: Katja Strancar; Audrey Boniface; Didier Blanot; Stanislav Gobec
Phosphinate inhibitors of UDP-N-acetylmuramoyl-L-alanyl-D-glutamate: L-lysine ligase (MurE).
Archiv der Pharmazie 2007;340(3):127-34.
2006: Meriem El Ghachi; Ahmed Bouhss; Hélène Barreteau; Thierry Touzé; Geneviève Auger; Didier Blanot; Dominique Mengin-Lecreulx
Colicin M exerts its bacteriolytic effect via enzymatic degradation of undecaprenyl phosphate-linked peptidoglycan precursors.
The Journal of biological chemistry 2006;281(32):22761-72.
2006: Audrey Boniface; Ahmed Bouhss; Dominique Mengin-Lecreulx; Didier Blanot
The MurE synthetase from Thermotoga maritima is endowed with an unusual D-lysine adding activity.
The Journal of biological chemistry 2006;281(23):15680-6.
2006: Anna Zaidman-Rémy; Mireille Hervé; Mickael Poidevin; Sebastien Pili-Floury; Min-Sung Kim; Didier Blanot; Byung-Ha Oh; Ryu Ueda; Dominique Mengin-Lecreulx; Bruno Lemaitre
The Drosophila amidase PGRP-LB modulates the immune response to bacterial infection.
Immunity 2006;24(4):463-73.
2006: Claudine Fraipont; Frédéric Sapunaric; Astrid Zervosen; Geneviève Auger; Bart Devreese; Thierry Lioux; Didier Blanot; Dominique Mengin-Lecreulx; Piet Herdewijn; Jozef Van Beeumen; Jean-Marie Frère; Martine Nguyen-Distèche
Glycosyl transferase activity of the Escherichia coli penicillin-binding protein 1b: specificity profile for the substrate.
Biochemistry 2006;45(12):4007-13.
2006: Katja Strancar; Didier Blanot; Stanislav Gobec
Design, synthesis and structure-activity relationships of new phosphinate inhibitors of MurD.
Bioorganic & medicinal chemistry letters 2006;16(2):343-8.
2005: Luca Guardabassi; Bruno Perichon; Jean Van Heijenoort; Didier Blanot; Patrice Courvalin
Glycopeptide resistance vanA operons in Paenibacillus strains isolated from soil.
Antimicrobial agents and chemotherapy 2005;49(10):4227-33.
2004: Leonardo Travassos; Stephen E Girardin; Dana J Philpott; Didier Blanot; Marie-Anne Nahori; Catherine Werts; Ivo G Boneca
Toll-like receptor 2-dependent bacterial sensing does not occur via peptidoglycan recognition.
EMBO reports 2004;5(10):1000-6.
2004: Ana Arbeloa; Jean-Emmanuel Hugonnet; Anne-Charlotte Sentilhes; Nathalie Josseaume; Lionel Dubost; Christelle Monsempes; Didier Blanot; Jean-Paul Brouard; Michel Arthur
Synthesis of mosaic peptidoglycan cross-bridges by hybrid peptidoglycan assembly pathways in gram-positive bacteria.
The Journal of biological chemistry 2004;279(40):41546-56.
2004: Meriem El Ghachi; Ahmed Bouhss; Didier Blanot; Dominique Mengin-Lecreulx
The bacA gene of Escherichia coli encodes an undecaprenyl pyrophosphate phosphatase activity.
The Journal of biological chemistry 2004;279(29):30106-13.
2004: Ahmed Bouhss; Muriel Crouvoisier; Didier Blanot; Dominique Mengin-Lecreulx
Purification and characterization of the bacterial MraY translocase catalyzing the first membrane step of peptidoglycan biosynthesis.
The Journal of biological chemistry 2004;279(29):29974-80.
2004: G Matrajt; Didier Blanot
Properties of synthetic ferrihydrite as an amino acid adsorbent and a promoter of peptide bond formation.
Amino acids 2004;26(2):153-8.
2004: Thérèse Stachyra; Christophe Dini; Paul Ferrari; Ahmed Bouhss; Jean Van Heijenoort; Dominique Mengin-Lecreulx; Didier Blanot; Jacques Biton; Dominique Le Beller
Fluorescence detection-based functional assay for high-throughput screening for MraY.
Antimicrobial agents and chemotherapy 2004;48(3):897-902.
2003: Lars Hesse; Julieanne M Bostock; Sébastien Dementin; Didier Blanot; Dominique Mengin-Lecreulx; Ian Chopra
Functional and biochemical analysis of Chlamydia trachomatis MurC, an enzyme displaying UDP-N-acetylmuramate:amino acid ligase activity.
Journal of bacteriology 2003;185(22):6507-12.
2003: Stephen E Girardin; Leonardo Travassos; Mireille Hervé; Didier Blanot; Ivo G Boneca; Dana J Philpott; Philippe J Sansonetti; Dominique Mengin-Lecreulx
Peptidoglycan molecular requirements allowing detection by Nod1 and Nod2.
The Journal of biological chemistry 2003;278(43):41702-8.
2003: Sabrina Biarrotte-Sorin; Antoine P Maillard; Jean Delettré; Wladimir Sougakoff; Didier Blanot; Karine Blondeau; Jean-Emmanuel Hugonnet; Claudine MAYER; Michel Arthur
Crystallization and preliminary X-ray analysis of Weissella viridescens FemX UDP-MurNAc-pentapeptide:l-alanine ligase.
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 6):1055-7.
2003: Geneviève Auger; Jean Van Heijenoort; Dominique Mengin-Lecreulx; Didier Blanot
A MurG assay which utilises a synthetic analogue of lipid I.
FEMS microbiology letters 2003;219(1):115-9.
2002: Jean-Luc Mainardi; Véronique Morel; Martine Fourgeaud; Julie Cremniter; Didier Blanot; Raymond Legrand; Claude Frehel; Michel Arthur; Jean Van Heijenoort; Laurent Gutmann
Balance between two transpeptidation mechanisms determines the expression of beta-lactam resistance in Enterococcus faecium.
The Journal of biological chemistry 2002;277(39):35801-7.
2002: Ahmed Bouhss; Sébastien Dementin; Jean Van Heijenoort; Claudine Parquet; Didier Blanot
MurC and MurD synthetases of peptidoglycan biosynthesis: borohydride trapping of acyl-phosphate intermediates.
Methods in enzymology 2002;354():189-96.
2001: Sébastien Dementin; Ahmed Bouhss; Geneviève Auger; Claudine Parquet; Dominique Mengin-Lecreulx; Otto Dideberg; Jean Van Heijenoort; Didier Blanot
Evidence of a functional requirement for a carbamoylated lysine residue in MurD, MurE and MurF synthetases as established by chemical rescue experiments.
European journal of biochemistry / FEBS 2001;268(22):5800-7.
2001: Luis A Augusto; K Le Blay; Geneviève Auger; Didier Blanot; Richard Chaby
Interaction of bacterial lipopolysaccharide with mouse surfactant protein C inserted into lipid vesicles.
American journal of physiology. Lung cellular and molecular physiology 2001;281(4):L776-85.
2001: Stanislav Gobec; Uros Urleb; Geneviève Auger; Didier Blanot
Synthesis and biochemical evaluation of some novel N-acyl phosphono- and phosphinoalanine derivatives as potential inhibitors of the D-glutamic acid-adding enzyme.
Die Pharmazie 2001;56(4):295-7.
2000: JA Bertrand; E Fanchon; Lydie Martin; Laurent Chantalat; Geneviève Auger; Didier Blanot; Jean Van Heijenoort; Otto Dideberg
"Open" structures of MurD: domain movements and structural similarities with folylpolyglutamate synthetase.
Journal of molecular biology 2000;301(5):1257-66.
1999: Dominique Mengin-Lecreulx; TJ Falla; Didier Blanot; Jean Van Heijenoort; D J Adams; Ian Chopra
Expression of the Staphylococcus aureus UDP-N-acetylmuramoyl- L-alanyl-D-glutamate:L-lysine ligase in Escherichia coli and effects on peptidoglycan biosynthesis and cell growth.
Journal of bacteriology 1999;181(19):5909-14.
1999: Ahmed Bouhss; Sébastien Dementin; Claudine Parquet; Dominique Mengin-Lecreulx; JA Bertrand; Dominique Le Beller; Otto Dideberg; Jean Van Heijenoort; Didier Blanot
Role of the ortholog and paralog amino acid invariants in the active site of the UDP-MurNAc-L-alanine:D-glutamate ligase (MurD).
Biochemistry 1999;38(38):12240-7.
1999: Ahmed Bouhss; Sébastien Dementin; Jean Van Heijenoort; Claudine Parquet; Didier Blanot
Formation of adenosine 5'-tetraphosphate from the acyl phosphate intermediate: a difference between the MurC and MurD synthetases of Escherichia coli.
FEBS letters 1999;453(1-2):15-9.
1999: JA Bertrand; Geneviève Auger; Lydie Martin; E Fanchon; Didier Blanot; Dominique Le Beller; Jean Van Heijenoort; Otto Dideberg
Determination of the MurD mechanism through crystallographic analysis of enzyme complexes.
Journal of molecular biology 1999;289(3):579-90.
1999: L Jolly; P Ferrari; Didier Blanot; Jean Van Heijenoort; Florence Fassy; Dominique Mengin-Lecreulx
Reaction mechanism of phosphoglucosamine mutase from Escherichia coli.
European journal of biochemistry / FEBS 1999;262(1):202-10.
1998: Geneviève Auger; Lydie Martin; J Bertrand; P Ferrari; E Fanchon; S Vaganay; Y Pétillot; Jean Van Heijenoort; Didier Blanot; Otto Dideberg
Large-scale preparation, purification, and crystallization of UDP-N-acetylmuramoyl-L-alanine: D-glutamate ligase from Escherichia coli.
Protein expression and purification 1998;13(1):23-9.
1998: F Nosal; A Masson; Raymond Legrand; Didier Blanot; Bernard SCHOOT; Jean Van Heijenoort; Claudine Parquet
Site-directed mutagenesis and chemical modification of the two cysteine residues of the UDP-N-acetylmuramoyl:L-alanine ligase of Escherichia coli.
FEBS letters 1998;426(3):309-13.
1997: Ahmed Bouhss; Dominique Mengin-Lecreulx; Didier Blanot; Jean Van Heijenoort; Claudine Parquet
Invariant amino acids in the Mur peptide synthetases of bacterial peptidoglycan synthesis and their modification by site-directed mutagenesis in the UDP-MurNAc:L-alanine ligase from Escherichia coli.
Biochemistry 1997;36(39):11556-63.
1997: JA Bertrand; Geneviève Auger; E Fanchon; Lydie Martin; Didier Blanot; Jean Van Heijenoort; Otto Dideberg
Crystal structure of UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase from Escherichia coli.
The EMBO journal 1997;16(12):3416-25.
1996: Geneviève Auger; Jean Van Heijenoort; J C Vederas; Didier Blanot
Effect of analogues of diaminopimelic acid on the meso-diaminopimelate-adding enzyme from Escherichia coli.
FEBS letters 1996;391(1-2):171-4.
1996: S Vaganay; M E Tanner; Jean Van Heijenoort; Didier Blanot
Study of the reaction mechanism of the D-glutamic acid-adding enzyme from Escherichia coli.
Microbial drug resistance (Larchmont, N.Y.) 1996;2(1):51-4.
1996: D Liger; A Masson; Didier Blanot; Jean Van Heijenoort; Claudine Parquet
Study of the overproduced uridine-diphosphate-N-acetylmuramate:L-alanine ligase from Escherichia coli.
Microbial drug resistance (Larchmont, N.Y.) 1996;2(1):25-7.
1995: D Liger; A Masson; Didier Blanot; Jean Van Heijenoort; Claudine Parquet
Over-production, purification and properties of the uridine-diphosphate-N-acetylmuramate:L-alanine ligase from Escherichia coli.
European journal of biochemistry / FEBS 1995;230(1):80-7.
1994: D Billot-Klein; Didier Blanot; Laurent Gutmann; Jean Van Heijenoort
Association constants for the binding of vancomycin and teicoplanin to N-acetyl-D-alanyl-D-alanine and N-acetyl-D-alanyl-D-serine.
The Biochemical journal 1994;304 ( Pt 3)():1021-2.
1994: Dominique Mengin-Lecreulx; Didier Blanot; Jean Van Heijenoort
Replacement of diaminopimelic acid by cystathionine or lanthionine in the peptidoglycan of Escherichia coli.
Journal of bacteriology 1994;176(14):4321-7.
1994: F Pratviel-Sosa; Francine Acher; F Trigalo; Didier Blanot; Robert Azerad; Jean Van Heijenoort
Effect of various analogues of D-glutamic acid on the D-glutamate-adding enzyme from Escherichia coli.
FEMS microbiology letters 1994;115(2-3):223-8.
1991: D Liger; Didier Blanot; Jean Van Heijenoort
Effect of various alanine analogues on the L-alanine-adding enzyme from Escherichia coli.
FEMS microbiology letters 1991;64(1):111-5.
1991: P Le Roux; Didier Blanot; Dominique Mengin-Lecreulx; Jean Van Heijenoort
Peptides containing 2-aminopimelic acid. Synthesis and study of in vitro effects on bacterial cells.
International journal of peptide and protein research 1991;37(2):103-11.
1990: C Michaud; Dominique Mengin-Lecreulx; Jean Van Heijenoort; Didier Blanot
Over-production, purification and properties of the uridine-diphosphate-N-acetylmuramoyl-L-alanyl-D-glutamate: meso-2,6-diaminopimelate ligase from Escherichia coli.
European journal of biochemistry / FEBS 1990;194(3):853-61.
1990: C Michaud; Claudine Parquet; B Flouret; Didier Blanot; Jean Van Heijenoort
Revised interpretation of the sequence containing the murE gene encoding the UDP-N-acetylmuramyl-tripeptide synthetase of Escherichia coli.
The Biochemical journal 1990;269(1):277-8.
1989: Geneviève Auger; Didier Blanot; Jean Van Heijenoort; C Nadal; M F Gournay; J J Winchenne; G A Boffa; P Lambin; P Maes; A Tartar
Purification and partial characterization of a hepatocyte antiproliferative glycopeptide.
Journal of cellular biochemistry 1989;40(4):439-51.
1988: M Abo-Ghalia; M Flegel; Didier Blanot; Jean Van Heijenoort
Synthesis of inhibitors of the meso-diaminopimelate-adding enzyme from Escherichia coli.
International journal of peptide and protein research 1988;32(3):208-22.
1988: Dominique Mengin-Lecreulx; C Michaud; C Richaud; Didier Blanot; Jean Van Heijenoort
Incorporation of LL-diaminopimelic acid into peptidoglycan of Escherichia coli mutants lacking diaminopimelate epimerase encoded by dapF.
Journal of bacteriology 1988;170(5):2031-9.
1987: C Michaud; Didier Blanot; B Flouret; Jean Van Heijenoort
Partial purification and specificity studies of the D-glutamate-adding and D-alanyl-D-alanine-adding enzymes from Escherichia coli K12.
European journal of biochemistry / FEBS 1987;166(3):631-7.
1987: Geneviève Auger; Didier Blanot; M Magnin; L N Gastinel; J M Pléau; M Dardenne; J F Bach
Synthesis and biological activity of eight thymulin analogues.
Biological chemistry Hoppe-Seyler 1987;368(5):463-70.
1985: M Abo-Ghalia; C Michaud; Didier Blanot; Jean Van Heijenoort
Specificity of the uridine-diphosphate-N-acetylmuramyl-L-alanyl-D-glutamate: meso-2,6-diaminopimelate synthetase from Escherichia coli.
European journal of biochemistry / FEBS 1985;153(1):81-7.
1984: Geneviève Auger; Didier Blanot
Synthesis of tritiated tuftsin and macrophage inhibitory tripeptide via acetylenic intermediates.
International journal of peptide and protein research 1984;24(1):60-5.
1983: Geneviève Auger; Didier Blanot; Jean Van Heijenoort; C Nadal; M F Gournay
Partial purification of rat and human serum factors inhibiting the G1-S transition in rat hepatocytes.
European journal of biochemistry / FEBS 1983;133(2):363-9.
1982: Geneviève Auger; Didier Blanot; E Bricas; J M Pléau; M Dardenne; J F Bach
Synthesis of an immunogenic conjugate and of two 125I-labelled derivatives of the "facteur thymique sérique".
Hoppe-Seyler's Zeitschrift für physiologische Chemie 1982;363(3):331-5.
1981: D Kaiserlian; A Dujic; M Dardenne; J F Bach; Didier Blanot; E Bricas
Prolongation of murine skin grafts by FTS and its synthetic analogues.
Clinical and experimental immunology 1981;45(2):338-43.
1980: J Martinez; Didier Blanot; Geneviève Auger; A Sasaki; E Bricas
Synthesis of analogs of the serum thymic nonapeptide, "facteur thymique serique" (FTS). Part II.
International journal of peptide and protein research 1980;16(4):267-79.